{"date_created":"2018-12-11T11:49:08Z","month":"10","citation":{"ieee":"R. Assis, A. Kondrashov, E. Koonin, and F. Kondrashov, “Nested genes and increasing organizational complexity of metazoan genomes,” <i>Trends in Genetics</i>, vol. 24, no. 10. Elsevier, pp. 475–478, 2008.","short":"R. Assis, A. Kondrashov, E. Koonin, F. Kondrashov, Trends in Genetics 24 (2008) 475–478.","mla":"Assis, Raquel, et al. “Nested Genes and Increasing Organizational Complexity of Metazoan Genomes.” <i>Trends in Genetics</i>, vol. 24, no. 10, Elsevier, 2008, pp. 475–78, doi:<a href=\"https://doi.org/10.1016/j.tig.2008.08.003\">10.1016/j.tig.2008.08.003</a>.","ama":"Assis R, Kondrashov A, Koonin E, Kondrashov F. Nested genes and increasing organizational complexity of metazoan genomes. <i>Trends in Genetics</i>. 2008;24(10):475-478. doi:<a href=\"https://doi.org/10.1016/j.tig.2008.08.003\">10.1016/j.tig.2008.08.003</a>","apa":"Assis, R., Kondrashov, A., Koonin, E., &#38; Kondrashov, F. (2008). Nested genes and increasing organizational complexity of metazoan genomes. <i>Trends in Genetics</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.tig.2008.08.003\">https://doi.org/10.1016/j.tig.2008.08.003</a>","ista":"Assis R, Kondrashov A, Koonin E, Kondrashov F. 2008. Nested genes and increasing organizational complexity of metazoan genomes. Trends in Genetics. 24(10), 475–478.","chicago":"Assis, Raquel, Alexey Kondrashov, Eugene Koonin, and Fyodor Kondrashov. “Nested Genes and Increasing Organizational Complexity of Metazoan Genomes.” <i>Trends in Genetics</i>. Elsevier, 2008. <a href=\"https://doi.org/10.1016/j.tig.2008.08.003\">https://doi.org/10.1016/j.tig.2008.08.003</a>."},"day":"01","page":"475 - 478","year":"2008","status":"public","publisher":"Elsevier","date_published":"2008-10-01T00:00:00Z","type":"journal_article","extern":1,"volume":24,"date_updated":"2021-01-12T08:21:49Z","publist_id":"6743","intvolume":"        24","title":"Nested genes and increasing organizational complexity of metazoan genomes","quality_controlled":0,"doi":"10.1016/j.tig.2008.08.003","author":[{"full_name":"Assis, Raquel","first_name":"Raquel","last_name":"Assis"},{"full_name":"Kondrashov, Alexey S","first_name":"Alexey","last_name":"Kondrashov"},{"last_name":"Koonin","full_name":"Koonin, Eugene V","first_name":"Eugene"},{"full_name":"Fyodor Kondrashov","first_name":"Fyodor","orcid":"0000-0001-8243-4694","last_name":"Kondrashov","id":"44FDEF62-F248-11E8-B48F-1D18A9856A87"}],"_id":"907","abstract":[{"text":"The most common form of protein-coding gene overlap in eukaryotes is a simple nested structure, whereby one gene is embedded in an intron of another. Analysis of nested protein-coding genes in vertebrates, fruit flies and nematodes revealed substantially higher rates of evolutionary gains than losses. The accumulation of nested gene structures could not be attributed to any obvious functional relationships between the genes involved and represents an increase of the organizational complexity of animal genomes via a neutral process.","lang":"eng"}],"publication":"Trends in Genetics","publication_status":"published","issue":"10"}