{"file_date_updated":"2020-07-14T12:47:10Z","oa":1,"user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","ddc":["004","519","576"],"external_id":{"isi":["000461126500071"]},"status":"public","project":[{"grant_number":"279307","_id":"2581B60A-B435-11E9-9278-68D0E5697425","call_identifier":"FP7","name":"Quantitative Graph Games: Theory and Applications"},{"_id":"2584A770-B435-11E9-9278-68D0E5697425","grant_number":"P 23499-N23","call_identifier":"FWF","name":"Modern Graph Algorithmic Techniques in Formal Verification"},{"grant_number":"S 11407_N23","_id":"25832EC2-B435-11E9-9278-68D0E5697425","call_identifier":"FWF","name":"Rigorous Systems Engineering"}],"date_created":"2018-12-18T13:22:58Z","month":"06","citation":{"chicago":"Pavlogiannis, Andreas, Josef Tkadlec, Krishnendu Chatterjee, and Martin A. Nowak. “Construction of Arbitrarily Strong Amplifiers of Natural Selection Using Evolutionary Graph Theory.” <i>Communications Biology</i>. Springer Nature, 2018. <a href=\"https://doi.org/10.1038/s42003-018-0078-7\">https://doi.org/10.1038/s42003-018-0078-7</a>.","ista":"Pavlogiannis A, Tkadlec J, Chatterjee K, Nowak MA. 2018. Construction of arbitrarily strong amplifiers of natural selection using evolutionary graph theory. Communications Biology. 1(1), 71.","apa":"Pavlogiannis, A., Tkadlec, J., Chatterjee, K., &#38; Nowak, M. A. (2018). Construction of arbitrarily strong amplifiers of natural selection using evolutionary graph theory. <i>Communications Biology</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s42003-018-0078-7\">https://doi.org/10.1038/s42003-018-0078-7</a>","short":"A. Pavlogiannis, J. Tkadlec, K. Chatterjee, M.A. Nowak, Communications Biology 1 (2018).","ama":"Pavlogiannis A, Tkadlec J, Chatterjee K, Nowak MA. Construction of arbitrarily strong amplifiers of natural selection using evolutionary graph theory. <i>Communications Biology</i>. 2018;1(1). doi:<a href=\"https://doi.org/10.1038/s42003-018-0078-7\">10.1038/s42003-018-0078-7</a>","mla":"Pavlogiannis, Andreas, et al. “Construction of Arbitrarily Strong Amplifiers of Natural Selection Using Evolutionary Graph Theory.” <i>Communications Biology</i>, vol. 1, no. 1, 71, Springer Nature, 2018, doi:<a href=\"https://doi.org/10.1038/s42003-018-0078-7\">10.1038/s42003-018-0078-7</a>.","ieee":"A. Pavlogiannis, J. Tkadlec, K. Chatterjee, and M. A. Nowak, “Construction of arbitrarily strong amplifiers of natural selection using evolutionary graph theory,” <i>Communications Biology</i>, vol. 1, no. 1. Springer Nature, 2018."},"article_processing_charge":"No","department":[{"_id":"KrCh"}],"abstract":[{"text":"Because of the intrinsic randomness of the evolutionary process, a mutant with a fitness advantage has some chance to be selected but no certainty. Any experiment that searches for advantageous mutants will lose many of them due to random drift. It is therefore of great interest to find population structures that improve the odds of advantageous mutants. Such structures are called amplifiers of natural selection: they increase the probability that advantageous mutants are selected. Arbitrarily strong amplifiers guarantee the selection of advantageous mutants, even for very small fitness advantage. Despite intensive research over the past decade, arbitrarily strong amplifiers have remained rare. Here we show how to construct a large variety of them. Our amplifiers are so simple that they could be useful in biotechnology, when optimizing biological molecules, or as a diagnostic tool, when searching for faster dividing cells or viruses. They could also occur in natural population structures.","lang":"eng"}],"article_number":"71","publication":"Communications Biology","publication_status":"published","related_material":{"record":[{"relation":"part_of_dissertation","status":"public","id":"7196"},{"relation":"popular_science","id":"5559","status":"public"}]},"author":[{"last_name":"Pavlogiannis","id":"49704004-F248-11E8-B48F-1D18A9856A87","first_name":"Andreas","full_name":"Pavlogiannis, Andreas","orcid":"0000-0002-8943-0722"},{"full_name":"Tkadlec, Josef","first_name":"Josef","orcid":"0000-0002-1097-9684","last_name":"Tkadlec","id":"3F24CCC8-F248-11E8-B48F-1D18A9856A87"},{"id":"2E5DCA20-F248-11E8-B48F-1D18A9856A87","last_name":"Chatterjee","orcid":"0000-0002-4561-241X","full_name":"Chatterjee, Krishnendu","first_name":"Krishnendu"},{"full_name":"Nowak, Martin A.","first_name":"Martin A.","last_name":"Nowak"}],"doi":"10.1038/s42003-018-0078-7","_id":"5751","isi":1,"publication_identifier":{"issn":["2399-3642"]},"type":"journal_article","has_accepted_license":"1","volume":1,"date_updated":"2024-02-21T13:48:42Z","date_published":"2018-06-14T00:00:00Z","tmp":{"short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"day":"14","ec_funded":1,"publisher":"Springer Nature","year":"2018","oa_version":"Published Version","issue":"1","title":"Construction of arbitrarily strong amplifiers of natural selection using evolutionary graph theory","scopus_import":"1","quality_controlled":"1","language":[{"iso":"eng"}],"intvolume":"         1","pubrep_id":"1045","file":[{"date_updated":"2020-07-14T12:47:10Z","creator":"dernst","file_id":"5752","file_name":"2018_CommBiology_Pavlogiannis.pdf","relation":"main_file","access_level":"open_access","checksum":"a9db825fa3b64a51ff3de035ec973b3e","date_created":"2018-12-18T13:37:04Z","file_size":1804194,"content_type":"application/pdf"}]}