{"date_updated":"2023-04-19T09:49:52Z","pmid":1,"article_processing_charge":"No","month":"12","day":"01","type":"journal_article","abstract":[{"lang":"eng","text":"We review the various factors that limit adaptation by natural selection. Recent discussion of constraints on selection and, conversely, of the factors that enhance 'evolvability', have concentrated on the kinds of variation that can be produced. Here, we emphasise that adaptation depends on how the various evolutionary processes shape variation in populations. We survey the limits that population genetics places on adaptive evolution, and discuss the relationship between disparate literatures. BioEssays 22:1075-1084, 2000. (C) 2000 John Wiley and Sons, Inc."}],"issue":"12","extern":"1","date_published":"2000-12-01T00:00:00Z","publication_status":"published","scopus_import":"1","publisher":"Wiley-Blackwell","user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17","date_created":"2018-12-11T12:07:58Z","oa_version":"None","status":"public","quality_controlled":"1","title":"Limits to natural selection","publication_identifier":{"issn":["0265-9247"]},"external_id":{"pmid":["11084623"]},"doi":"10.1002/1521-1878(200012)22:12&lt;1075::AID-BIES5&gt;3.0.CO;2-M","page":"1075 - 1084","publication":"BioEssays","author":[{"first_name":"Nicholas H","last_name":"Barton","full_name":"Barton, Nicholas H","id":"4880FE40-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8548-5240"},{"full_name":"Partridge, Linda","first_name":"Linda","last_name":"Partridge"}],"language":[{"iso":"eng"}],"_id":"4273","article_type":"original","citation":{"ieee":"N. H. Barton and L. Partridge, “Limits to natural selection,” <i>BioEssays</i>, vol. 22, no. 12. Wiley-Blackwell, pp. 1075–1084, 2000.","mla":"Barton, Nicholas H., and Linda Partridge. “Limits to Natural Selection.” <i>BioEssays</i>, vol. 22, no. 12, Wiley-Blackwell, 2000, pp. 1075–84, doi:<a href=\"https://doi.org/10.1002/1521-1878(200012)22:12&#38;lt;1075::AID-BIES5&#38;gt;3.0.CO;2-M\">10.1002/1521-1878(200012)22:12&#38;lt;1075::AID-BIES5&#38;gt;3.0.CO;2-M</a>.","short":"N.H. Barton, L. Partridge, BioEssays 22 (2000) 1075–1084.","ama":"Barton NH, Partridge L. Limits to natural selection. <i>BioEssays</i>. 2000;22(12):1075-1084. doi:<a href=\"https://doi.org/10.1002/1521-1878(200012)22:12&#38;lt;1075::AID-BIES5&#38;gt;3.0.CO;2-M\">10.1002/1521-1878(200012)22:12&#38;lt;1075::AID-BIES5&#38;gt;3.0.CO;2-M</a>","chicago":"Barton, Nicholas H, and Linda Partridge. “Limits to Natural Selection.” <i>BioEssays</i>. Wiley-Blackwell, 2000. <a href=\"https://doi.org/10.1002/1521-1878(200012)22:12&#38;lt;1075::AID-BIES5&#38;gt;3.0.CO;2-M\">https://doi.org/10.1002/1521-1878(200012)22:12&#38;lt;1075::AID-BIES5&#38;gt;3.0.CO;2-M</a>.","ista":"Barton NH, Partridge L. 2000. Limits to natural selection. BioEssays. 22(12), 1075–1084.","apa":"Barton, N. H., &#38; Partridge, L. (2000). Limits to natural selection. <i>BioEssays</i>. Wiley-Blackwell. <a href=\"https://doi.org/10.1002/1521-1878(200012)22:12&#38;lt;1075::AID-BIES5&#38;gt;3.0.CO;2-M\">https://doi.org/10.1002/1521-1878(200012)22:12&#38;lt;1075::AID-BIES5&#38;gt;3.0.CO;2-M</a>"},"year":"2000","publist_id":"1818","volume":22,"intvolume":"        22","acknowledgement":"We thank Brian Charlesworth, Toby Johnson, and two anonymous referees for helpful discussions and criticism of the manuscript."}