{"oa":1,"oa_version":"Published Version","user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17","date_created":"2018-12-11T12:07:54Z","publisher":"Genetics Society of America","scopus_import":"1","title":"Associations between cytoplasmic and nuclear loci in hybridizing populations","quality_controlled":"1","status":"public","type":"journal_article","day":"01","month":"11","article_processing_charge":"No","pmid":1,"date_updated":"2023-06-06T12:19:54Z","date_published":"2002-11-01T00:00:00Z","extern":"1","publication_status":"published","issue":"3","main_file_link":[{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1462324/","open_access":"1"}],"abstract":[{"text":"We extend current multilocus models to describe the effects of migration, recombination, selection, and nonrandom mating on sets of genes in diploids with varied modes of inheritance, allowing us to consider the patterns of nuclear and cytonuclear associations (disequilibria) under various models of migration. We show the relationship between the multilocus notation recently presented by Kirkpatrick, Johnson, and Barton (developed from previous work by Barton and Turelli) and the cytonuclear parameterization of Asmussen, Arnold, and Avise and extend this notation to describe associations between cytoplasmic elements and multiple nuclear genes. Under models with sexual symmetry, both nuclear-nuclear and cytonuclear disequilibria are equivalent. They differ, however, in cases involving some type of sexual asymmetry, which is then reflected in the asymmetric inheritance of cytoplasmic markers. An example given is the case of different migration rates in males and females; simulations using 2, 3, 4, or 5 unlinked autosomal markers with a maternally inherited cytoplasmic marker illustrate how nuclear-nuclear and cytonuclear associations can be used to separately estimate female and male migration rates. The general framework developed here allows us to investigate conditions where associations between loci with different modes of inheritance are not equivalent and to use this nonequivalence to test for deviations from simple models of admixture. ","lang":"eng"}],"intvolume":"       162","publist_id":"1836","volume":162,"year":"2002","acknowledgement":"The authors thank Toby Johnson for his helpful comments on this manuscript. This work was supported by a National Science Foundation NATO postdoctoral fellowship and National Science Foundation grants DEB-9813335 and DEB-0108242 to M.E.O.; N.H.B. gratefully acknowledges the support of the Darwin Trust of Edinburgh and the National Environmental Research Council.","page":"1469 - 1485","doi":"10.1093/genetics/162.3.1469","author":[{"last_name":"Orive","first_name":"Maria","full_name":"Orive, Maria"},{"first_name":"Nicholas H","last_name":"Barton","full_name":"Barton, Nicholas H","id":"4880FE40-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8548-5240"}],"publication":"Genetics","external_id":{"pmid":["12454089"]},"publication_identifier":{"issn":["0016-6731"]},"article_type":"original","citation":{"ieee":"M. Orive and N. H. Barton, “Associations between cytoplasmic and nuclear loci in hybridizing populations,” <i>Genetics</i>, vol. 162, no. 3. Genetics Society of America, pp. 1469–1485, 2002.","mla":"Orive, Maria, and Nicholas H. Barton. “Associations between Cytoplasmic and Nuclear Loci in Hybridizing Populations.” <i>Genetics</i>, vol. 162, no. 3, Genetics Society of America, 2002, pp. 1469–85, doi:<a href=\"https://doi.org/10.1093/genetics/162.3.1469\">10.1093/genetics/162.3.1469</a>.","short":"M. Orive, N.H. Barton, Genetics 162 (2002) 1469–1485.","ama":"Orive M, Barton NH. Associations between cytoplasmic and nuclear loci in hybridizing populations. <i>Genetics</i>. 2002;162(3):1469-1485. doi:<a href=\"https://doi.org/10.1093/genetics/162.3.1469\">10.1093/genetics/162.3.1469</a>","chicago":"Orive, Maria, and Nicholas H Barton. “Associations between Cytoplasmic and Nuclear Loci in Hybridizing Populations.” <i>Genetics</i>. Genetics Society of America, 2002. <a href=\"https://doi.org/10.1093/genetics/162.3.1469\">https://doi.org/10.1093/genetics/162.3.1469</a>.","apa":"Orive, M., &#38; Barton, N. H. (2002). Associations between cytoplasmic and nuclear loci in hybridizing populations. <i>Genetics</i>. Genetics Society of America. <a href=\"https://doi.org/10.1093/genetics/162.3.1469\">https://doi.org/10.1093/genetics/162.3.1469</a>","ista":"Orive M, Barton NH. 2002. Associations between cytoplasmic and nuclear loci in hybridizing populations. Genetics. 162(3), 1469–1485."},"language":[{"iso":"eng"}],"_id":"4259"}