{"title":"A Bond for a Lifetime: Employing Membrane Nanotubes from Living Cells to Determine Receptor-Ligand Kinetics","author":[{"last_name":"Krieg","first_name":"Michael","full_name":"Krieg, Michael"},{"first_name":"Jonne","full_name":"Helenius, Jonne","last_name":"Helenius"},{"id":"39427864-F248-11E8-B48F-1D18A9856A87","last_name":"Heisenberg","orcid":"0000-0002-0912-4566","full_name":"Heisenberg, Carl-Philipp J","first_name":"Carl-Philipp J"},{"full_name":"Mueller, Daniel","first_name":"Daniel","last_name":"Mueller"}],"doi":"10.1002/anie.200803552","_id":"4180","oa_version":"None","abstract":[{"text":"(Figure Presented) The name's Bond: Separated cells form membranous nanotubes whose tips are tethered by adhesive bonds (see picture). The lifetime of receptor-ligand interactions can be measured by using membrane nanotubes of living cells as constant force actuators. Because the nanotubes are extruded from living cells at conditions approaching the physiological, cellular processes can be both studied and utilized. ","lang":"eng"}],"issue":"50","publication":"Angewandte Chemie - International Edition","publication_status":"published","type":"journal_article","extern":"1","volume":47,"publist_id":"1939","date_updated":"2021-01-12T07:55:06Z","language":[{"iso":"eng"}],"intvolume":"        47","day":"01","page":"9775 - 9777","status":"public","publisher":"Wiley-Blackwell","year":"2008","date_published":"2008-12-01T00:00:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_processing_charge":"No","date_created":"2018-12-11T12:07:26Z","month":"12","citation":{"ista":"Krieg M, Helenius J, Heisenberg C-PJ, Mueller D. 2008. A Bond for a Lifetime: Employing Membrane Nanotubes from Living Cells to Determine Receptor-Ligand Kinetics. Angewandte Chemie - International Edition. 47(50), 9775–9777.","chicago":"Krieg, Michael, Jonne Helenius, Carl-Philipp J Heisenberg, and Daniel Mueller. “A Bond for a Lifetime: Employing Membrane Nanotubes from Living Cells to Determine Receptor-Ligand Kinetics.” <i>Angewandte Chemie - International Edition</i>. Wiley-Blackwell, 2008. <a href=\"https://doi.org/10.1002/anie.200803552\">https://doi.org/10.1002/anie.200803552</a>.","apa":"Krieg, M., Helenius, J., Heisenberg, C.-P. J., &#38; Mueller, D. (2008). A Bond for a Lifetime: Employing Membrane Nanotubes from Living Cells to Determine Receptor-Ligand Kinetics. <i>Angewandte Chemie - International Edition</i>. Wiley-Blackwell. <a href=\"https://doi.org/10.1002/anie.200803552\">https://doi.org/10.1002/anie.200803552</a>","short":"M. Krieg, J. Helenius, C.-P.J. Heisenberg, D. Mueller, Angewandte Chemie - International Edition 47 (2008) 9775–9777.","mla":"Krieg, Michael, et al. “A Bond for a Lifetime: Employing Membrane Nanotubes from Living Cells to Determine Receptor-Ligand Kinetics.” <i>Angewandte Chemie - International Edition</i>, vol. 47, no. 50, Wiley-Blackwell, 2008, pp. 9775–77, doi:<a href=\"https://doi.org/10.1002/anie.200803552\">10.1002/anie.200803552</a>.","ama":"Krieg M, Helenius J, Heisenberg C-PJ, Mueller D. A Bond for a Lifetime: Employing Membrane Nanotubes from Living Cells to Determine Receptor-Ligand Kinetics. <i>Angewandte Chemie - International Edition</i>. 2008;47(50):9775-9777. doi:<a href=\"https://doi.org/10.1002/anie.200803552\">10.1002/anie.200803552</a>","ieee":"M. Krieg, J. Helenius, C.-P. J. Heisenberg, and D. Mueller, “A Bond for a Lifetime: Employing Membrane Nanotubes from Living Cells to Determine Receptor-Ligand Kinetics,” <i>Angewandte Chemie - International Edition</i>, vol. 47, no. 50. Wiley-Blackwell, pp. 9775–9777, 2008."}}