{"abstract":[{"lang":"eng","text":"The shuttling of leukocytes between the bloodstream and interstitial tissues involves different locomotion strategies that are governed by locally presented soluble and cell-bound signals. Recent studies have furthered our understanding of the rapidly advancing field of leukocyte migration, particularly regarding cellular and subcellular events at the level of the venular wall. Furthermore, emerging cellular models are now addressing the transition from an adherent mode to a non-adherent state, incorporating mechanisms that support an efficient migratory profile of leukocytes in the interstitial tissue beyond the venular wall."}],"issue":"5","publication":"Nature Reviews Molecular Cell Biology","publication_status":"published","quality_controlled":0,"title":"Breaching multiple barriers: leukocyte motility through venular walls and the interstitium","_id":"3956","doi":"10.1038/nrm2889","author":[{"last_name":"Nourshargh","full_name":"Nourshargh, Sussan","first_name":"Sussan"},{"last_name":"Hordijk","first_name":"Peter","full_name":"Hordijk, Peter L"},{"full_name":"Michael Sixt","first_name":"Michael K","orcid":"0000-0002-6620-9179","last_name":"Sixt","id":"41E9FBEA-F248-11E8-B48F-1D18A9856A87"}],"intvolume":"        11","extern":1,"type":"journal_article","date_updated":"2021-01-12T07:53:27Z","publist_id":"2170","volume":11,"date_published":"2010-05-01T00:00:00Z","day":"01","status":"public","publisher":"Nature Publishing Group","year":"2010","page":"366 - 378","month":"05","date_created":"2018-12-11T12:06:06Z","citation":{"apa":"Nourshargh, S., Hordijk, P., &#38; Sixt, M. K. (2010). Breaching multiple barriers: leukocyte motility through venular walls and the interstitium. <i>Nature Reviews Molecular Cell Biology</i>. Nature Publishing Group. <a href=\"https://doi.org/10.1038/nrm2889\">https://doi.org/10.1038/nrm2889</a>","ista":"Nourshargh S, Hordijk P, Sixt MK. 2010. Breaching multiple barriers: leukocyte motility through venular walls and the interstitium. Nature Reviews Molecular Cell Biology. 11(5), 366–378.","chicago":"Nourshargh, Sussan, Peter Hordijk, and Michael K Sixt. “Breaching Multiple Barriers: Leukocyte Motility through Venular Walls and the Interstitium.” <i>Nature Reviews Molecular Cell Biology</i>. Nature Publishing Group, 2010. <a href=\"https://doi.org/10.1038/nrm2889\">https://doi.org/10.1038/nrm2889</a>.","ieee":"S. Nourshargh, P. Hordijk, and M. K. Sixt, “Breaching multiple barriers: leukocyte motility through venular walls and the interstitium,” <i>Nature Reviews Molecular Cell Biology</i>, vol. 11, no. 5. Nature Publishing Group, pp. 366–378, 2010.","ama":"Nourshargh S, Hordijk P, Sixt MK. Breaching multiple barriers: leukocyte motility through venular walls and the interstitium. <i>Nature Reviews Molecular Cell Biology</i>. 2010;11(5):366-378. doi:<a href=\"https://doi.org/10.1038/nrm2889\">10.1038/nrm2889</a>","mla":"Nourshargh, Sussan, et al. “Breaching Multiple Barriers: Leukocyte Motility through Venular Walls and the Interstitium.” <i>Nature Reviews Molecular Cell Biology</i>, vol. 11, no. 5, Nature Publishing Group, 2010, pp. 366–78, doi:<a href=\"https://doi.org/10.1038/nrm2889\">10.1038/nrm2889</a>.","short":"S. Nourshargh, P. Hordijk, M.K. Sixt, Nature Reviews Molecular Cell Biology 11 (2010) 366–378."}}