{"title":"A small number of open Ca(2+) channels trigger transmitter release at a central GABAergic synapse","quality_controlled":0,"author":[{"last_name":"Bucurenciu","first_name":"Iancu","full_name":"Bucurenciu, Iancu"},{"last_name":"Bischofberger","first_name":"Josef","full_name":"Bischofberger, Josef"},{"id":"353C1B58-F248-11E8-B48F-1D18A9856A87","last_name":"Jonas","orcid":"0000-0001-5001-4804","first_name":"Peter M","full_name":"Peter Jonas"}],"doi":"10.1038/nn.2461 ","_id":"3829","abstract":[{"text":"To determine the number of open Ca(2+) channels necessary for transmitter release at the inhibitory basket cell-granule cell synapse in rat hippocampus, we combined presynaptic Ca(2+) imaging, recording of postsynaptic currents and modeling. We found that that the opening of three or fewer Ca(2+) channels triggered transmitter release. Furthermore, a small number of Ca(2+) channels were able to evoke release with high temporal precision, despite stochastic Ca(2+) channel opening.","lang":"eng"}],"issue":"1","publication_status":"published","publication":"Nature Neuroscience","type":"journal_article","extern":1,"volume":13,"publist_id":"2380","date_updated":"2021-01-12T07:52:29Z","intvolume":"        13","day":"01","page":"19 - 21","publisher":"Nature Publishing Group","status":"public","year":"2010","date_published":"2010-01-01T00:00:00Z","date_created":"2018-12-11T12:05:24Z","month":"01","citation":{"apa":"Bucurenciu, I., Bischofberger, J., &#38; Jonas, P. M. (2010). A small number of open Ca(2+) channels trigger transmitter release at a central GABAergic synapse. <i>Nature Neuroscience</i>. Nature Publishing Group. <a href=\"https://doi.org/10.1038/nn.2461 \">https://doi.org/10.1038/nn.2461 </a>","chicago":"Bucurenciu, Iancu, Josef Bischofberger, and Peter M Jonas. “A Small Number of Open Ca(2+) Channels Trigger Transmitter Release at a Central GABAergic Synapse.” <i>Nature Neuroscience</i>. Nature Publishing Group, 2010. <a href=\"https://doi.org/10.1038/nn.2461 \">https://doi.org/10.1038/nn.2461 </a>.","ista":"Bucurenciu I, Bischofberger J, Jonas PM. 2010. A small number of open Ca(2+) channels trigger transmitter release at a central GABAergic synapse. Nature Neuroscience. 13(1), 19–21.","ieee":"I. Bucurenciu, J. Bischofberger, and P. M. Jonas, “A small number of open Ca(2+) channels trigger transmitter release at a central GABAergic synapse,” <i>Nature Neuroscience</i>, vol. 13, no. 1. Nature Publishing Group, pp. 19–21, 2010.","mla":"Bucurenciu, Iancu, et al. “A Small Number of Open Ca(2+) Channels Trigger Transmitter Release at a Central GABAergic Synapse.” <i>Nature Neuroscience</i>, vol. 13, no. 1, Nature Publishing Group, 2010, pp. 19–21, doi:<a href=\"https://doi.org/10.1038/nn.2461 \">10.1038/nn.2461 </a>.","ama":"Bucurenciu I, Bischofberger J, Jonas PM. A small number of open Ca(2+) channels trigger transmitter release at a central GABAergic synapse. <i>Nature Neuroscience</i>. 2010;13(1):19-21. doi:<a href=\"https://doi.org/10.1038/nn.2461 \">10.1038/nn.2461 </a>","short":"I. Bucurenciu, J. Bischofberger, P.M. Jonas, Nature Neuroscience 13 (2010) 19–21."}}