{"title":"Modeling network dynamics: the lac operon, a case study","quality_controlled":0,"status":"public","year":"2003","publisher":"Rockefeller University Press","intvolume":"       161","oa":1,"volume":161,"publist_id":"2475","date_created":"2018-12-11T12:04:58Z","_id":"3752","main_file_link":[{"url":"http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172934/?tool=pubmed","open_access":"1"}],"abstract":[{"lang":"eng","text":"We use the lac operon in Escherichia coli as a prototype system to illustrate the current state, applicability, and limitations of modeling the dynamics of cellular networks. We integrate three different levels of description (molecular, cellular, and that of cell population) into a single model, which seems to capture many experimental aspects of the system."}],"extern":1,"date_published":"2003-01-12T00:00:00Z","citation":{"ieee":"J. Vilar, C. C. Guet, and S. Leibler, “Modeling network dynamics: the lac operon, a case study,” <i>Journal of Cell Biology</i>, vol. 161, no. 3. Rockefeller University Press, pp. 471–476, 2003.","mla":"Vilar, Jose, et al. “Modeling Network Dynamics: The Lac Operon, a Case Study.” <i>Journal of Cell Biology</i>, vol. 161, no. 3, Rockefeller University Press, 2003, pp. 471–76, doi:<a href=\"https://doi.org/10.1083/jcb.200301125\">10.1083/jcb.200301125</a>.","short":"J. Vilar, C.C. Guet, S. Leibler, Journal of Cell Biology 161 (2003) 471–476.","ama":"Vilar J, Guet CC, Leibler S. Modeling network dynamics: the lac operon, a case study. <i>Journal of Cell Biology</i>. 2003;161(3):471-476. doi:<a href=\"https://doi.org/10.1083/jcb.200301125\">10.1083/jcb.200301125</a>","ista":"Vilar J, Guet CC, Leibler S. 2003. Modeling network dynamics: the lac operon, a case study. Journal of Cell Biology. 161(3), 471–476.","chicago":"Vilar, Jose, Calin C Guet, and Stanislas Leibler. “Modeling Network Dynamics: The Lac Operon, a Case Study.” <i>Journal of Cell Biology</i>. Rockefeller University Press, 2003. <a href=\"https://doi.org/10.1083/jcb.200301125\">https://doi.org/10.1083/jcb.200301125</a>.","apa":"Vilar, J., Guet, C. C., &#38; Leibler, S. (2003). Modeling network dynamics: the lac operon, a case study. <i>Journal of Cell Biology</i>. Rockefeller University Press. <a href=\"https://doi.org/10.1083/jcb.200301125\">https://doi.org/10.1083/jcb.200301125</a>"},"publication_status":"published","issue":"3","month":"01","date_updated":"2021-01-12T07:51:57Z","type":"journal_article","author":[{"full_name":"Vilar,Jose M","first_name":"Jose","last_name":"Vilar"},{"last_name":"Guet","first_name":"Calin C","id":"47F8433E-F248-11E8-B48F-1D18A9856A87","full_name":"Calin Guet","orcid":"0000-0001-6220-2052"},{"first_name":"Stanislas","last_name":"Leibler","full_name":"Leibler, Stanislas"}],"publication":"Journal of Cell Biology","day":"12","doi":"10.1083/jcb.200301125","page":"471 - 476"}