{"day":"01","type":"journal_article","date_updated":"2021-12-15T15:16:50Z","month":"12","article_processing_charge":"No","issue":"3","date_published":"1979-12-01T00:00:00Z","publication_status":"published","extern":"1","abstract":[{"lang":"eng","text":"The effect of a cline as a barrier to gene flow at closely linked, weakly selected loci is investigated using a continuous diffusion model. It is shown that a linked cline induces a step in the frequency of a neutral allele, which is proportional to the gradient in neutral allele frequency and to the inverse of the recombination rate. A barrier to dispersal or a local region of low abundance has a similar effect (Nagylaki, 1976). The cline will block the flow of neutral alleles over a region of chromosome roughly 2s/t map units long. However, a slightly advantageous allele will be little affected, and must be very tightly linked to be delayed for long."}],"main_file_link":[{"url":"https://www.nature.com/articles/hdy197986","open_access":"1"}],"date_created":"2018-12-11T12:04:33Z","user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","oa":1,"oa_version":"Published Version","scopus_import":"1","publisher":"Springer Nature","status":"public","title":"Gene flow past a cline","quality_controlled":"1","doi":"10.1038/hdy.1979.86","page":"333 - 339","author":[{"orcid":"0000-0002-8548-5240","full_name":"Barton, Nicholas H","id":"4880FE40-F248-11E8-B48F-1D18A9856A87","first_name":"Nicholas H","last_name":"Barton"}],"publication":"Heredity","publication_identifier":{"eissn":["1365-2540"],"issn":["0018-067X"]},"citation":{"short":"N.H. Barton, Heredity 43 (1979) 333–339.","ista":"Barton NH. 1979. Gene flow past a cline. Heredity. 43(3), 333–339.","chicago":"Barton, Nicholas H. “Gene Flow Past a Cline.” <i>Heredity</i>. Springer Nature, 1979. <a href=\"https://doi.org/10.1038/hdy.1979.86\">https://doi.org/10.1038/hdy.1979.86</a>.","apa":"Barton, N. H. (1979). Gene flow past a cline. <i>Heredity</i>. Springer Nature. <a href=\"https://doi.org/10.1038/hdy.1979.86\">https://doi.org/10.1038/hdy.1979.86</a>","ama":"Barton NH. Gene flow past a cline. <i>Heredity</i>. 1979;43(3):333-339. doi:<a href=\"https://doi.org/10.1038/hdy.1979.86\">10.1038/hdy.1979.86</a>","ieee":"N. H. Barton, “Gene flow past a cline,” <i>Heredity</i>, vol. 43, no. 3. Springer Nature, pp. 333–339, 1979.","mla":"Barton, Nicholas H. “Gene Flow Past a Cline.” <i>Heredity</i>, vol. 43, no. 3, Springer Nature, 1979, pp. 333–39, doi:<a href=\"https://doi.org/10.1038/hdy.1979.86\">10.1038/hdy.1979.86</a>."},"article_type":"original","language":[{"iso":"eng"}],"_id":"3673","volume":43,"publist_id":"2710","intvolume":"        43","year":"1979","acknowledgement":"I would like to thank Dr G. M. Hewitt for stimulating discussions, and for his comments on the manuscript. This work was supported by the Natural Environmental Research Council.\r\n"}