{"abstract":[{"text":"We investigate the probability of fixation of a chromosome rearrangement in a subdivided population, concentrating on the limit where migration is so large relative to selection (m ≫ s) that the population can be thought of as being continuously distributed. We study two demes, and one- and two-dimensional populations. For two demes, the probability of fixation in the limit of high migration approximates that of a population with twice the size of a single deme: migration therefore greatly reduces the fixation probability. However, this behavior does not extend to a large array of demes. Then, the fixation probability depends primarily on neighborhood size (Nb), and may be appreciable even with strong selection and free gene flow (≈exp(-B·Nb) in one dimension, ≈exp(-B\\cdotNb) in two dimensions). Our results are close to those for the more tractable case of a polygenic character under disruptive selection.","lang":"eng"}],"publisher":"Wiley-Blackwell","user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17","external_id":{"pmid":["28568824"]},"page":"499 - 517","oa_version":"None","pmid":1,"publication":"Evolution","doi":"10.1111/j.1558-5646.1991.tb04326.x","date_updated":"2022-03-02T10:37:19Z","day":"01","extern":"1","language":[{"iso":"eng"}],"year":"1991","main_file_link":[{"url":"http://www.jstor.org/stable/2409908"}],"publist_id":"2735","article_type":"original","publication_identifier":{"issn":["0014-3820"],"eissn":["1558-5646"]},"intvolume":" 45","month":"05","author":[{"full_name":"Barton, Nicholas H","orcid":"0000-0002-8548-5240","id":"4880FE40-F248-11E8-B48F-1D18A9856A87","last_name":"Barton","first_name":"Nicholas H"},{"first_name":"Shahin","last_name":"Rouhani","full_name":"Rouhani, Shahin"}],"citation":{"short":"N.H. Barton, S. Rouhani, Evolution 45 (1991) 499–517.","chicago":"Barton, Nicholas H, and Shahin Rouhani. “The Probability of Fixation of a New Karyotype in a Continuous Population.” Evolution. Wiley-Blackwell, 1991. https://doi.org/10.1111/j.1558-5646.1991.tb04326.x.","ama":"Barton NH, Rouhani S. The probability of fixation of a new karyotype in a continuous population. Evolution. 1991;45(3):499-517. doi:10.1111/j.1558-5646.1991.tb04326.x","ieee":"N. H. Barton and S. Rouhani, “The probability of fixation of a new karyotype in a continuous population,” Evolution, vol. 45, no. 3. Wiley-Blackwell, pp. 499–517, 1991.","ista":"Barton NH, Rouhani S. 1991. The probability of fixation of a new karyotype in a continuous population. Evolution. 45(3), 499–517.","mla":"Barton, Nicholas H., and Shahin Rouhani. “The Probability of Fixation of a New Karyotype in a Continuous Population.” Evolution, vol. 45, no. 3, Wiley-Blackwell, 1991, pp. 499–517, doi:10.1111/j.1558-5646.1991.tb04326.x.","apa":"Barton, N. H., & Rouhani, S. (1991). The probability of fixation of a new karyotype in a continuous population. Evolution. Wiley-Blackwell. https://doi.org/10.1111/j.1558-5646.1991.tb04326.x"},"title":"The probability of fixation of a new karyotype in a continuous population","date_published":"1991-05-01T00:00:00Z","date_created":"2018-12-11T12:04:25Z","issue":"3","type":"journal_article","article_processing_charge":"No","status":"public","_id":"3648","quality_controlled":"1","publication_status":"published","volume":45}