{"publist_id":"2865","language":[{"iso":"eng"}],"intvolume":"        21","scopus_import":"1","quality_controlled":"1","title":"Reliability and state dependence of pyramidal cell-interneuron synapses in the hippocampus: an ensemble approach in the behaving rat","oa_version":"None","issue":"1","pmid":1,"day":"01","publisher":"Elsevier","year":"1998","article_type":"original","date_published":"1998-07-01T00:00:00Z","extern":"1","type":"journal_article","date_updated":"2022-08-29T14:03:55Z","volume":21,"publication_identifier":{"issn":["0896-6273"]},"_id":"3521","doi":"10.1016/S0896-6273(00)80525-5","author":[{"id":"3FA14672-F248-11E8-B48F-1D18A9856A87","last_name":"Csicsvari","orcid":"0000-0002-5193-4036","first_name":"Jozsef L","full_name":"Csicsvari, Jozsef L"},{"last_name":"Hirase","first_name":"Hajima","full_name":"Hirase, Hajima"},{"full_name":"Czurkó, András","first_name":"András","last_name":"Czurkó"},{"last_name":"Buzsáki","full_name":"Buzsáki, György","first_name":"György"}],"abstract":[{"lang":"eng","text":"Spike transmission probability between pyramidal cells and interneurons in the CA1 pyramidal layer was investigated in the behaving rat by the simultaneous recording of neuronal ensembles. Population synchrony was strongest during sharp wave (SPW) bursts. However, the increase was three times larger for pyramidal cells than for interneurons. The contribution of single pyramidal cells to the discharge of interneurons was often large (up to 0.6 probability), as assessed by the presence of significant (&lt;3 ms) peaks in the cross-correlogram. Complex-spike bursts were more effective than single spikes. Single cell contribution was higher between SPW bursts than during SPWs or theta activity. Hence, single pyramidal cells can reliably discharge interneurons, and the probability of spike transmission is behavior dependent."}],"publication":"Neuron","publication_status":"published","acknowledgement":"We thank C. King, R. Miles, M. Recce, and the anonymous reviewers for their constructive comments on the manuscript. This work was supported by the National Institutes of Health (NS34994, MH54671 1P41RR09754), the Human Frontier Science Program, and the Whitehall Foundation.","article_processing_charge":"No","month":"07","date_created":"2018-12-11T12:03:46Z","citation":{"apa":"Csicsvari, J. L., Hirase, H., Czurkó, A., &#38; Buzsáki, G. (1998). Reliability and state dependence of pyramidal cell-interneuron synapses in the hippocampus: an ensemble approach in the behaving rat. <i>Neuron</i>. Elsevier. <a href=\"https://doi.org/10.1016/S0896-6273(00)80525-5\">https://doi.org/10.1016/S0896-6273(00)80525-5</a>","chicago":"Csicsvari, Jozsef L, Hajima Hirase, András Czurkó, and György Buzsáki. “Reliability and State Dependence of Pyramidal Cell-Interneuron Synapses in the Hippocampus: An Ensemble Approach in the Behaving Rat.” <i>Neuron</i>. Elsevier, 1998. <a href=\"https://doi.org/10.1016/S0896-6273(00)80525-5\">https://doi.org/10.1016/S0896-6273(00)80525-5</a>.","ista":"Csicsvari JL, Hirase H, Czurkó A, Buzsáki G. 1998. Reliability and state dependence of pyramidal cell-interneuron synapses in the hippocampus: an ensemble approach in the behaving rat. Neuron. 21(1), 179–189.","ieee":"J. L. Csicsvari, H. Hirase, A. Czurkó, and G. Buzsáki, “Reliability and state dependence of pyramidal cell-interneuron synapses in the hippocampus: an ensemble approach in the behaving rat,” <i>Neuron</i>, vol. 21, no. 1. Elsevier, pp. 179–189, 1998.","short":"J.L. Csicsvari, H. Hirase, A. Czurkó, G. Buzsáki, Neuron 21 (1998) 179–189.","ama":"Csicsvari JL, Hirase H, Czurkó A, Buzsáki G. Reliability and state dependence of pyramidal cell-interneuron synapses in the hippocampus: an ensemble approach in the behaving rat. <i>Neuron</i>. 1998;21(1):179-189. doi:<a href=\"https://doi.org/10.1016/S0896-6273(00)80525-5\">10.1016/S0896-6273(00)80525-5</a>","mla":"Csicsvari, Jozsef L., et al. “Reliability and State Dependence of Pyramidal Cell-Interneuron Synapses in the Hippocampus: An Ensemble Approach in the Behaving Rat.” <i>Neuron</i>, vol. 21, no. 1, Elsevier, 1998, pp. 179–89, doi:<a href=\"https://doi.org/10.1016/S0896-6273(00)80525-5\">10.1016/S0896-6273(00)80525-5</a>."},"external_id":{"pmid":["9697862 "]},"status":"public","page":"179 - 189","user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17"}