{"intvolume":"         4","language":[{"iso":"eng"}],"publist_id":"2927","issue":"3","oa_version":"None","main_file_link":[{"url":"https://www.sciencedirect.com/science/article/pii/0959438894900981?via%3Dihub"}],"title":"Mechanisms shaping glutamate-mediated excitatory postsynaptic currents in the CNS","quality_controlled":"1","scopus_import":"1","pmid":1,"date_published":"1994-06-01T00:00:00Z","year":"1994","publisher":"Elsevier","article_type":"original","day":"01","publication_identifier":{"issn":["0959-4388"]},"volume":4,"date_updated":"2022-06-03T11:26:52Z","type":"journal_article","extern":"1","publication":"Current Opinion in Neurobiology","publication_status":"published","abstract":[{"text":"Excitatory postsynaptic currents in neurones of the central nervous system have a dual-component time course that results from the co-activation of AMPA/kainate-type and NMDA-type glutamate receptors. New approaches in electrophysiology and molecular biology have provided a better understanding of the factors that determine the kinectics of excitatory postsynaptic currents. Recent studies suggest that the time course of neurotransmitter concentration in the synaptic cleft, the gating properties of the native channels, and the glutamate receptor subunit composition all appear to be important factors.","lang":"eng"}],"author":[{"first_name":"Peter M","full_name":"Jonas, Peter M","orcid":"0000-0001-5001-4804","last_name":"Jonas","id":"353C1B58-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Spruston, Nelson","first_name":"Nelson","last_name":"Spruston"}],"doi":"10.1016/0959-4388(94)90098-1","_id":"3460","citation":{"short":"P.M. Jonas, N. Spruston, Current Opinion in Neurobiology 4 (1994) 366–372.","mla":"Jonas, Peter M., and Nelson Spruston. “Mechanisms Shaping Glutamate-Mediated Excitatory Postsynaptic Currents in the CNS.” <i>Current Opinion in Neurobiology</i>, vol. 4, no. 3, Elsevier, 1994, pp. 366–72, doi:<a href=\"https://doi.org/10.1016/0959-4388(94)90098-1\">10.1016/0959-4388(94)90098-1</a>.","ama":"Jonas PM, Spruston N. Mechanisms shaping glutamate-mediated excitatory postsynaptic currents in the CNS. <i>Current Opinion in Neurobiology</i>. 1994;4(3):366-372. doi:<a href=\"https://doi.org/10.1016/0959-4388(94)90098-1\">10.1016/0959-4388(94)90098-1</a>","ieee":"P. M. Jonas and N. Spruston, “Mechanisms shaping glutamate-mediated excitatory postsynaptic currents in the CNS,” <i>Current Opinion in Neurobiology</i>, vol. 4, no. 3. Elsevier, pp. 366–372, 1994.","chicago":"Jonas, Peter M, and Nelson Spruston. “Mechanisms Shaping Glutamate-Mediated Excitatory Postsynaptic Currents in the CNS.” <i>Current Opinion in Neurobiology</i>. Elsevier, 1994. <a href=\"https://doi.org/10.1016/0959-4388(94)90098-1\">https://doi.org/10.1016/0959-4388(94)90098-1</a>.","ista":"Jonas PM, Spruston N. 1994. Mechanisms shaping glutamate-mediated excitatory postsynaptic currents in the CNS. Current Opinion in Neurobiology. 4(3), 366–372.","apa":"Jonas, P. M., &#38; Spruston, N. (1994). Mechanisms shaping glutamate-mediated excitatory postsynaptic currents in the CNS. <i>Current Opinion in Neurobiology</i>. Elsevier. <a href=\"https://doi.org/10.1016/0959-4388(94)90098-1\">https://doi.org/10.1016/0959-4388(94)90098-1</a>"},"date_created":"2018-12-11T12:03:27Z","month":"06","article_processing_charge":"No","acknowledgement":"We thank JGG Borst, N Burnashev, M Häusser, G Stuart and A Viilarroel for critically reading the manuscript and E von Kitzing and A Roth for doing the simulations and for many helpful discussions. Supported by the Deutsche Forschungsgemeinschaft (SFB 317-B14) and the Alexander von Humboldt Foundation. ","user_id":"ea97e931-d5af-11eb-85d4-e6957dddbf17","page":"366 - 372","status":"public","external_id":{"pmid":["7522678 "]}}