{"citation":{"ieee":"J. Mravec <i>et al.</i>, “Interaction of PIN and PGP transport mechanisms in auxin distribution-dependent development,” <i>Development</i>, vol. 135, no. 20. Company of Biologists, pp. 3345–3354, 2008.","mla":"Mravec, Jozef, et al. “Interaction of PIN and PGP Transport Mechanisms in Auxin Distribution-Dependent Development.” <i>Development</i>, vol. 135, no. 20, Company of Biologists, 2008, pp. 3345–54, doi:<a href=\"https://doi.org/10.1242/dev.021071\">10.1242/dev.021071</a>.","short":"J. Mravec, M. Kubeš, A. Bielach, V. Gaykova, J. Petrášek, P. Skůpa, S. Chand, E. Benková, E. Zažímalová, J. Friml, Development 135 (2008) 3345–3354.","ama":"Mravec J, Kubeš M, Bielach A, et al. Interaction of PIN and PGP transport mechanisms in auxin distribution-dependent development. <i>Development</i>. 2008;135(20):3345-3354. doi:<a href=\"https://doi.org/10.1242/dev.021071\">10.1242/dev.021071</a>","ista":"Mravec J, Kubeš M, Bielach A, Gaykova V, Petrášek J, Skůpa P, Chand S, Benková E, Zažímalová E, Friml J. 2008. Interaction of PIN and PGP transport mechanisms in auxin distribution-dependent development. Development. 135(20), 3345–3354.","chicago":"Mravec, Jozef, Martin Kubeš, Agnieszka Bielach, Vassilena Gaykova, Jan Petrášek, Petr Skůpa, Suresh Chand, Eva Benková, Eva Zažímalová, and Jiří Friml. “Interaction of PIN and PGP Transport Mechanisms in Auxin Distribution-Dependent Development.” <i>Development</i>. Company of Biologists, 2008. <a href=\"https://doi.org/10.1242/dev.021071\">https://doi.org/10.1242/dev.021071</a>.","apa":"Mravec, J., Kubeš, M., Bielach, A., Gaykova, V., Petrášek, J., Skůpa, P., … Friml, J. (2008). Interaction of PIN and PGP transport mechanisms in auxin distribution-dependent development. <i>Development</i>. Company of Biologists. <a href=\"https://doi.org/10.1242/dev.021071\">https://doi.org/10.1242/dev.021071</a>"},"date_published":"2008-10-15T00:00:00Z","extern":1,"publication_status":"published","issue":"20","_id":"3044","abstract":[{"text":"The signalling molecule auxin controls plant morphogenesis via its activity gradients, which are produced by intercellular auxin transport. Cellular auxin efflux is the rate-limiting step in this process and depends on PIN and phosphoglycoprotein (PGP) auxin transporters. Mutual roles for these proteins in auxin transport are unclear, as is the significance of their interactions for plant development. Here, we have analysed the importance of the functional interaction between PIN- and PGP-dependent auxin transport in development. We show by analysis of inducible overexpression lines that PINs and PGPs define distinct auxin transport mechanisms: both mediate auxin efflux but they play diverse developmental roles. Components of both systems are expressed during embryogenesis, organogenesis and tropisms, and they interact genetically in both synergistic and antagonistic fashions. A concerted action of PIN- and PGP-dependent efflux systems is required for asymmetric auxin distribution during these processes. We propose a model in which PGP-mediated efflux controls auxin levels in auxin channel-forming cells and, thus, auxin availability for PIN-dependent vectorial auxin movement.","lang":"eng"}],"type":"journal_article","day":"15","publication":"Development","author":[{"first_name":"Jozef","last_name":"Mravec","full_name":"Mravec, Jozef"},{"last_name":"Kubeš","first_name":"Martin","full_name":"Kubeš, Martin"},{"full_name":"Bielach, Agnieszka","first_name":"Agnieszka","last_name":"Bielach"},{"last_name":"Gaykova","first_name":"Vassilena","full_name":"Gaykova, Vassilena"},{"full_name":"Petrášek, Jan","last_name":"Petrášek","first_name":"Jan"},{"last_name":"Skůpa","first_name":"Petr","full_name":"Skůpa, Petr"},{"full_name":"Chand, Suresh","last_name":"Chand","first_name":"Suresh"},{"orcid":"0000-0002-8510-9739","first_name":"Eva","last_name":"Benková","full_name":"Eva Benková","id":"38F4F166-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Eva","last_name":"Zažímalová","full_name":"Zažímalová, Eva"},{"orcid":"0000-0002-8302-7596","id":"4159519E-F248-11E8-B48F-1D18A9856A87","full_name":"Jirí Friml","first_name":"Jirí","last_name":"Friml"}],"page":"3345 - 3354","doi":"10.1242/dev.021071","month":"10","date_updated":"2021-01-12T07:40:39Z","title":"Interaction of PIN and PGP transport mechanisms in auxin distribution-dependent development","quality_controlled":0,"status":"public","intvolume":"       135","date_created":"2018-12-11T12:01:02Z","publist_id":"3658","volume":135,"year":"2008","publisher":"Company of Biologists"}