{"publist_id":"3695","volume":311,"date_created":"2018-12-11T12:00:50Z","intvolume":"       311","publisher":"American Association for the Advancement of Science","year":"2006","status":"public","title":"A molecular framework for plant regeneration","quality_controlled":0,"doi":"10.1126/science.1121790","page":"385 - 388","day":"20","publication":"Science","author":[{"last_name":"Xu","first_name":"Jian","full_name":"Xu, Jian"},{"full_name":"Hofhuis, Hugo","last_name":"Hofhuis","first_name":"Hugo"},{"last_name":"Heidstra","first_name":"Renze","full_name":"Heidstra, Renze"},{"full_name":"Sauer, Michael","first_name":"Michael","last_name":"Sauer"},{"orcid":"0000-0002-8302-7596","id":"4159519E-F248-11E8-B48F-1D18A9856A87","full_name":"Jirí Friml","first_name":"Jirí","last_name":"Friml"},{"first_name":"Ben","last_name":"Scheres","full_name":"Scheres, Ben"}],"type":"journal_article","date_updated":"2021-01-12T07:40:25Z","month":"01","issue":"5759","extern":1,"citation":{"mla":"Xu, Jian, et al. “A Molecular Framework for Plant Regeneration.” <i>Science</i>, vol. 311, no. 5759, American Association for the Advancement of Science, 2006, pp. 385–88, doi:<a href=\"https://doi.org/10.1126/science.1121790\">10.1126/science.1121790</a>.","ieee":"J. Xu, H. Hofhuis, R. Heidstra, M. Sauer, J. Friml, and B. Scheres, “A molecular framework for plant regeneration,” <i>Science</i>, vol. 311, no. 5759. American Association for the Advancement of Science, pp. 385–388, 2006.","ista":"Xu J, Hofhuis H, Heidstra R, Sauer M, Friml J, Scheres B. 2006. A molecular framework for plant regeneration. Science. 311(5759), 385–388.","chicago":"Xu, Jian, Hugo Hofhuis, Renze Heidstra, Michael Sauer, Jiří Friml, and Ben Scheres. “A Molecular Framework for Plant Regeneration.” <i>Science</i>. American Association for the Advancement of Science, 2006. <a href=\"https://doi.org/10.1126/science.1121790\">https://doi.org/10.1126/science.1121790</a>.","apa":"Xu, J., Hofhuis, H., Heidstra, R., Sauer, M., Friml, J., &#38; Scheres, B. (2006). A molecular framework for plant regeneration. <i>Science</i>. American Association for the Advancement of Science. <a href=\"https://doi.org/10.1126/science.1121790\">https://doi.org/10.1126/science.1121790</a>","ama":"Xu J, Hofhuis H, Heidstra R, Sauer M, Friml J, Scheres B. A molecular framework for plant regeneration. <i>Science</i>. 2006;311(5759):385-388. doi:<a href=\"https://doi.org/10.1126/science.1121790\">10.1126/science.1121790</a>","short":"J. Xu, H. Hofhuis, R. Heidstra, M. Sauer, J. Friml, B. Scheres, Science 311 (2006) 385–388."},"date_published":"2006-01-20T00:00:00Z","publication_status":"published","abstract":[{"lang":"eng","text":"Plants and some animals have a profound capacity to regenerate organs from adult tissues. Molecular mechanisms for regeneration have, however, been largely unexplored. Here we investigate a local regeneration response in Arabidopsis roots. Laser-induced wounding disrupts the flow of auxin-a cell-fate-instructive plant hormone-in root tips, and we demonstrate that resulting cell-fate changes require the PLETHORA, SHORTROOT, and SCARECROW transcription factors. These transcription factors regulate the expression and polar position of PIN auxin efflux-facilitating membrane proteins to reconstitute auxin transport in renewed root tips. Thus, a regeneration mechanism using embryonic root stem-cell patterning factors first responds to and subsequently stabilizes a new hormone distribution."}],"_id":"3008"}