{"intvolume":"     14137","volume":14137,"year":"2023","file_date_updated":"2024-02-16T08:26:32Z","acknowledgement":"This work was supported by the Czech Foundation grant No. GA22-10845S, Grant Agency of Masaryk University grant No. MUNI/G/1771/2020, and the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie Grant Agreement No. 101034413.","ddc":["000"],"project":[{"grant_number":"101034413","name":"IST-BRIDGE: International postdoctoral program","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","call_identifier":"H2020"}],"page":"18-35","doi":"10.1007/978-3-031-42697-1_2","publication":"21st International Conference on Computational Methods in Systems Biology","author":[{"first_name":"Nikola","last_name":"Beneš","full_name":"Beneš, Nikola"},{"full_name":"Brim, Luboš","first_name":"Luboš","last_name":"Brim"},{"orcid":"0000-0003-1993-0331","first_name":"Samuel","last_name":"Pastva","full_name":"Pastva, Samuel","id":"07c5ea74-f61c-11ec-a664-aa7c5d957b2b"},{"first_name":"David","last_name":"Šafránek","full_name":"Šafránek, David"},{"first_name":"Eva","last_name":"Šmijáková","full_name":"Šmijáková, Eva"}],"has_accepted_license":"1","publication_identifier":{"eissn":["1611-3349"],"isbn":["9783031426964"],"issn":["0302-9743"]},"ec_funded":1,"citation":{"ieee":"N. Beneš, L. Brim, S. Pastva, D. Šafránek, and E. Šmijáková, “Phenotype control of partially specified boolean networks,” in <i>21st International Conference on Computational Methods in Systems Biology</i>, Luxembourg City, Luxembourg, 2023, vol. 14137, pp. 18–35.","mla":"Beneš, Nikola, et al. “Phenotype Control of Partially Specified Boolean Networks.” <i>21st International Conference on Computational Methods in Systems Biology</i>, vol. 14137, Springer Nature, 2023, pp. 18–35, doi:<a href=\"https://doi.org/10.1007/978-3-031-42697-1_2\">10.1007/978-3-031-42697-1_2</a>.","short":"N. Beneš, L. Brim, S. Pastva, D. Šafránek, E. Šmijáková, in:, 21st International Conference on Computational Methods in Systems Biology, Springer Nature, 2023, pp. 18–35.","ista":"Beneš N, Brim L, Pastva S, Šafránek D, Šmijáková E. 2023. Phenotype control of partially specified boolean networks. 21st International Conference on Computational Methods in Systems Biology. CMSB: Computational Methods in Systems Biology, LNBI, vol. 14137, 18–35.","apa":"Beneš, N., Brim, L., Pastva, S., Šafránek, D., &#38; Šmijáková, E. (2023). Phenotype control of partially specified boolean networks. In <i>21st International Conference on Computational Methods in Systems Biology</i> (Vol. 14137, pp. 18–35). Luxembourg City, Luxembourg: Springer Nature. <a href=\"https://doi.org/10.1007/978-3-031-42697-1_2\">https://doi.org/10.1007/978-3-031-42697-1_2</a>","chicago":"Beneš, Nikola, Luboš Brim, Samuel Pastva, David Šafránek, and Eva Šmijáková. “Phenotype Control of Partially Specified Boolean Networks.” In <i>21st International Conference on Computational Methods in Systems Biology</i>, 14137:18–35. Springer Nature, 2023. <a href=\"https://doi.org/10.1007/978-3-031-42697-1_2\">https://doi.org/10.1007/978-3-031-42697-1_2</a>.","ama":"Beneš N, Brim L, Pastva S, Šafránek D, Šmijáková E. Phenotype control of partially specified boolean networks. In: <i>21st International Conference on Computational Methods in Systems Biology</i>. Vol 14137. Springer Nature; 2023:18-35. doi:<a href=\"https://doi.org/10.1007/978-3-031-42697-1_2\">10.1007/978-3-031-42697-1_2</a>"},"conference":{"location":"Luxembourg City, Luxembourg","end_date":"2023-09-15","name":"CMSB: Computational Methods in Systems Biology","start_date":"2023-09-13"},"language":[{"iso":"eng"}],"_id":"14411","oa":1,"oa_version":"Submitted Version","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_created":"2023-10-08T22:01:18Z","publisher":"Springer Nature","scopus_import":"1","title":"Phenotype control of partially specified boolean networks","quality_controlled":"1","status":"public","alternative_title":["LNBI"],"file":[{"checksum":"6f71bdaedb770b52380222fd9f4d7937","relation":"main_file","creator":"spastva","access_level":"open_access","file_name":"cmsb2023.pdf","content_type":"application/pdf","date_updated":"2024-02-16T08:26:32Z","file_size":691582,"date_created":"2024-02-16T08:26:32Z","success":1,"file_id":"14997"}],"type":"conference","day":"09","month":"09","article_processing_charge":"No","tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"date_updated":"2024-02-20T09:02:04Z","date_published":"2023-09-09T00:00:00Z","publication_status":"published","department":[{"_id":"ToHe"}],"abstract":[{"lang":"eng","text":"Partially specified Boolean networks (PSBNs) represent a promising framework for the qualitative modelling of biological systems in which the logic of interactions is not completely known. Phenotype control aims to stabilise the network in states exhibiting specific traits.\r\nIn this paper, we define the phenotype control problem in the context of asynchronous PSBNs and propose a novel semi-symbolic algorithm for solving this problem with permanent variable perturbations."}]}