{"date_published":"2023-10-01T00:00:00Z","publication_status":"published","issue":"2","department":[{"_id":"JiFr"}],"abstract":[{"text":"The 3′,5′-cyclic adenosine monophosphate (cAMP) is a versatile second messenger in many mammalian signaling pathways. However, its role in plants remains not well-recognized. Recent discovery of adenylate cyclase (AC) activity for transport inhibitor response 1/auxin-signaling F-box proteins (TIR1/AFB) auxin receptors and the demonstration of its importance for canonical auxin signaling put plant cAMP research back into spotlight. This insight briefly summarizes the well-established cAMP signaling pathways in mammalian cells and describes the turbulent and controversial history of plant cAMP research highlighting the major progress and the unresolved points. We also briefly review the current paradigm of auxin signaling to provide a background for the discussion on the AC activity of TIR1/AFB auxin receptors and its potential role in transcriptional auxin signaling as well as impact of these discoveries on plant cAMP research in general.","lang":"eng"}],"type":"journal_article","file":[{"file_id":"14898","success":1,"file_size":974464,"date_created":"2024-01-29T11:21:43Z","date_updated":"2024-01-29T11:21:43Z","content_type":"application/pdf","file_name":"2023_NewPhytologist_Qi.pdf","access_level":"open_access","creator":"dernst","relation":"main_file","checksum":"6d9bbd45b8e7bb3ceee2586d447bacb2"}],"day":"01","month":"10","article_processing_charge":"Yes (via OA deal)","pmid":1,"date_updated":"2024-01-29T11:21:55Z","tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"title":"Tale of cAMP as a second messenger in auxin signaling and beyond","quality_controlled":"1","status":"public","oa_version":"Published Version","oa":1,"date_created":"2023-07-23T22:01:13Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publisher":"Wiley","scopus_import":"1","citation":{"short":"L. Qi, J. Friml, New Phytologist 240 (2023) 489–495.","ama":"Qi L, Friml J. Tale of cAMP as a second messenger in auxin signaling and beyond. <i>New Phytologist</i>. 2023;240(2):489-495. doi:<a href=\"https://doi.org/10.1111/nph.19123\">10.1111/nph.19123</a>","chicago":"Qi, Linlin, and Jiří Friml. “Tale of CAMP as a Second Messenger in Auxin Signaling and Beyond.” <i>New Phytologist</i>. Wiley, 2023. <a href=\"https://doi.org/10.1111/nph.19123\">https://doi.org/10.1111/nph.19123</a>.","ista":"Qi L, Friml J. 2023. Tale of cAMP as a second messenger in auxin signaling and beyond. New Phytologist. 240(2), 489–495.","apa":"Qi, L., &#38; Friml, J. (2023). Tale of cAMP as a second messenger in auxin signaling and beyond. <i>New Phytologist</i>. Wiley. <a href=\"https://doi.org/10.1111/nph.19123\">https://doi.org/10.1111/nph.19123</a>","ieee":"L. Qi and J. Friml, “Tale of cAMP as a second messenger in auxin signaling and beyond,” <i>New Phytologist</i>, vol. 240, no. 2. Wiley, pp. 489–495, 2023.","mla":"Qi, Linlin, and Jiří Friml. “Tale of CAMP as a Second Messenger in Auxin Signaling and Beyond.” <i>New Phytologist</i>, vol. 240, no. 2, Wiley, 2023, pp. 489–95, doi:<a href=\"https://doi.org/10.1111/nph.19123\">10.1111/nph.19123</a>."},"article_type":"original","_id":"13266","language":[{"iso":"eng"}],"has_accepted_license":"1","author":[{"orcid":"0000-0001-5187-8401","last_name":"Qi","first_name":"Linlin","full_name":"Qi, Linlin","id":"44B04502-A9ED-11E9-B6FC-583AE6697425"},{"orcid":"0000-0002-8302-7596","id":"4159519E-F248-11E8-B48F-1D18A9856A87","full_name":"Friml, Jiří","first_name":"Jiří","last_name":"Friml"}],"publication":"New Phytologist","page":"489-495","doi":"10.1111/nph.19123","external_id":{"isi":["001026321500001"],"pmid":["37434303"]},"publication_identifier":{"eissn":["1469-8137"],"issn":["0028-646X"]},"isi":1,"acknowledgement":"We gratefully acknowledge our brave colleagues, whose excellent efforts kept the plant cAMP research going in the last two decades. The authors were financially supported by the Austrian Science Fund (FWF): I 6123 and P 37051-B.","file_date_updated":"2024-01-29T11:21:43Z","project":[{"_id":"bd76d395-d553-11ed-ba76-f678c14f9033","name":"Peptide receptor complexes for auxin canalization and regeneration in Arabidopsis","grant_number":"I06123"},{"grant_number":"P37051","_id":"7bcece63-9f16-11ee-852c-ae94e099eeb6","name":"Guanylate cyclase activity of TIR1/AFBs auxin receptors"}],"ddc":["580"],"intvolume":"       240","volume":240,"year":"2023"}