{"date_published":"2021-01-15T00:00:00Z","article_type":"letter_note","publisher":"American Chemical Society","year":"2021","day":"15","pmid":1,"issue":"2","oa_version":"Published Version","main_file_link":[{"url":"https://doi.org/10.1021/acs.orglett.0c04026","open_access":"1"}],"quality_controlled":"1","scopus_import":"1","title":"Visible-light-mediated oxidative debenzylation enables the use of benzyl ethers as temporary protecting groups","intvolume":"        23","language":[{"iso":"eng"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa":1,"status":"public","page":"514-518","external_id":{"pmid":["33400534"]},"citation":{"ieee":"C. Cavedon, E. T. Sletten, A. Madani, O. Niemeyer, P. H. Seeberger, and B. Pieber, “Visible-light-mediated oxidative debenzylation enables the use of benzyl ethers as temporary protecting groups,” <i>Organic Letters</i>, vol. 23, no. 2. American Chemical Society, pp. 514–518, 2021.","short":"C. Cavedon, E.T. Sletten, A. Madani, O. Niemeyer, P.H. Seeberger, B. Pieber, Organic Letters 23 (2021) 514–518.","mla":"Cavedon, Cristian, et al. “Visible-Light-Mediated Oxidative Debenzylation Enables the Use of Benzyl Ethers as Temporary Protecting Groups.” <i>Organic Letters</i>, vol. 23, no. 2, American Chemical Society, 2021, pp. 514–18, doi:<a href=\"https://doi.org/10.1021/acs.orglett.0c04026\">10.1021/acs.orglett.0c04026</a>.","ama":"Cavedon C, Sletten ET, Madani A, Niemeyer O, Seeberger PH, Pieber B. Visible-light-mediated oxidative debenzylation enables the use of benzyl ethers as temporary protecting groups. <i>Organic Letters</i>. 2021;23(2):514-518. doi:<a href=\"https://doi.org/10.1021/acs.orglett.0c04026\">10.1021/acs.orglett.0c04026</a>","apa":"Cavedon, C., Sletten, E. T., Madani, A., Niemeyer, O., Seeberger, P. H., &#38; Pieber, B. (2021). Visible-light-mediated oxidative debenzylation enables the use of benzyl ethers as temporary protecting groups. <i>Organic Letters</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acs.orglett.0c04026\">https://doi.org/10.1021/acs.orglett.0c04026</a>","ista":"Cavedon C, Sletten ET, Madani A, Niemeyer O, Seeberger PH, Pieber B. 2021. Visible-light-mediated oxidative debenzylation enables the use of benzyl ethers as temporary protecting groups. Organic Letters. 23(2), 514–518.","chicago":"Cavedon, Cristian, Eric T. Sletten, Amiera Madani, Olaf Niemeyer, Peter H. Seeberger, and Bartholomäus Pieber. “Visible-Light-Mediated Oxidative Debenzylation Enables the Use of Benzyl Ethers as Temporary Protecting Groups.” <i>Organic Letters</i>. American Chemical Society, 2021. <a href=\"https://doi.org/10.1021/acs.orglett.0c04026\">https://doi.org/10.1021/acs.orglett.0c04026</a>."},"month":"01","date_created":"2022-08-25T11:13:05Z","article_processing_charge":"No","publication":"Organic Letters","publication_status":"published","abstract":[{"text":"The cleavage of benzyl ethers by catalytic hydrogenolysis or Birch reduction suffers from poor functional group compatibility and limits their use as a protecting group. The visible-light-mediated debenzylation disclosed here renders benzyl ethers temporary protective groups, enabling new orthogonal protection strategies. Using 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) as a stoichiometric or catalytic photooxidant, benzyl ethers can be cleaved in the presence of azides, alkenes, and alkynes. The reaction time can be reduced from hours to minutes in continuous flow.","lang":"eng"}],"_id":"11981","author":[{"last_name":"Cavedon","full_name":"Cavedon, Cristian","first_name":"Cristian"},{"last_name":"Sletten","full_name":"Sletten, Eric T.","first_name":"Eric T."},{"full_name":"Madani, Amiera","first_name":"Amiera","last_name":"Madani"},{"last_name":"Niemeyer","full_name":"Niemeyer, Olaf","first_name":"Olaf"},{"last_name":"Seeberger","first_name":"Peter H.","full_name":"Seeberger, Peter H."},{"last_name":"Pieber","id":"93e5e5b2-0da6-11ed-8a41-af589a024726","full_name":"Pieber, Bartholomäus","first_name":"Bartholomäus","orcid":"0000-0001-8689-388X"}],"doi":"10.1021/acs.orglett.0c04026","publication_identifier":{"issn":["1523-7060"],"eissn":["1523-7052"]},"date_updated":"2023-02-21T10:10:16Z","volume":23,"extern":"1","type":"journal_article"}