Daria E Siekhaus
Siekhaus Group
30 Publications
2023 | Published | Journal Article | IST-REx-ID: 13316 |

J. Y. Toshima et al., “The yeast endocytic early/sorting compartment exists as an independent sub-compartment within the trans-Golgi network,” eLife, vol. 12. eLife Sciences Publications, 2023.
[Published Version]
View
| Files available
| DOI
| WoS
| PubMed | Europe PMC
2023 | Published | Journal Article | IST-REx-ID: 14316 |

M. Nagano, K. Aoshima, H. Shimamura, D. E. Siekhaus, J. Y. Toshima, and J. Toshima, “Distinct role of TGN-resident clathrin adaptors for Vps21p activation in the TGN-endosome trafficking pathway,” Journal of Cell Science, vol. 136, no. 17. The Company of Biologists, 2023.
[Preprint]
View
| DOI
| Download Preprint (ext.)
| PubMed | Europe PMC
2022 | Published | Journal Article | IST-REx-ID: 12080 |

M. Enshoji et al., “Eps15/Pan1p is a master regulator of the late stages of the endocytic pathway,” Journal of Cell Biology, vol. 221, no. 10. Rockefeller University Press, 2022.
[Published Version]
View
| Files available
| DOI
| WoS
| PubMed | Europe PMC
2022 | Published | Journal Article | IST-REx-ID: 10614 |

V. Belyaeva et al., “Fos regulates macrophage infiltration against surrounding tissue resistance by a cortical actin-based mechanism in Drosophila,” PLoS Biology, vol. 20, no. 1. Public Library of Science, p. e3001494, 2022.
[Published Version]
View
| Files available
| DOI
| WoS
| PubMed | Europe PMC
2022 | Published | Journal Article | IST-REx-ID: 10712 |

M. Roblek et al., “The solute carrier MFSD1 decreases β1 integrin’s activation status and thus tumor metastasis,” Frontiers in Oncology, vol. 12. Frontiers, 2022.
[Published Version]
View
| Files available
| DOI
| WoS
2022 | Published | Journal Article | IST-REx-ID: 10713 |

M. Akhmanova et al., “Cell division in tissues enables macrophage infiltration,” Science, vol. 376, no. 6591. American Association for the Advancement of Science, pp. 394–396, 2022.
[Preprint]
View
| DOI
| Download Preprint (ext.)
| WoS
| PubMed | Europe PMC
2022 | Published | Journal Article | IST-REx-ID: 10714 |

E. T. Martin et al., “A translation control module coordinates germline stem cell differentiation with ribosome biogenesis during Drosophila oogenesis,” Developmental Cell, vol. 57, no. 7. Elsevier, p. 883–900.e10, 2022.
[Preprint]
View
| DOI
| Download Preprint (ext.)
| WoS
2022 | Published | Journal Article | IST-REx-ID: 10918 |

S. Emtenani et al., “Macrophage mitochondrial bioenergetics and tissue invasion are boosted by an Atossa-Porthos axis in Drosophila,” The Embo Journal, vol. 41. Embo Press, 2022.
[Published Version]
View
| Files available
| DOI
| WoS
2021 | Published | Journal Article | IST-REx-ID: 9363 |

Á. Inglés Prieto et al., “Optogenetic delivery of trophic signals in a genetic model of Parkinson’s disease,” PLoS genetics, vol. 17, no. 4. Public Library of Science, p. e1009479, 2021.
[Published Version]
View
| Files available
| DOI
| WoS
2020 | Submitted | Preprint | IST-REx-ID: 8557 |

V. Belyaeva et al., “Cortical actin properties controlled by Drosophila Fos aid macrophage infiltration against surrounding tissue resistance,” bioRxiv. .
[Preprint]
View
| Files available
| DOI
| Download Preprint (ext.)
2020 | Published | Journal Article | IST-REx-ID: 7466 |

K. Kierdorf et al., “Muscle function and homeostasis require cytokine inhibition of AKT activity in Drosophila,” eLife, vol. 9. eLife Sciences Publications, 2020.
[Published Version]
View
| Files available
| DOI
| WoS
2019 | Published | Journal Article | IST-REx-ID: 8 |

G. Trébuchet et al., “The Repo homeodomain transcription factor suppresses hematopoiesis in Drosophila and preserves the glial fate,” Journal of Neuroscience, vol. 39, no. 2. Society for Neuroscience, pp. 238–255, 2019.
[Published Version]
View
| Files available
| DOI
| WoS
| PubMed | Europe PMC
2019 | Published | Journal Article | IST-REx-ID: 6187 |

K. Valosková et al., “A conserved major facilitator superfamily member orchestrates a subset of O-glycosylation to aid macrophage tissue invasion,” eLife, vol. 8. eLife Sciences Publications, 2019.
[Published Version]
View
| Files available
| DOI
| WoS
2019 | Published | Journal Article | IST-REx-ID: 7097 |

M. Nagano, J. Y. Toshima, D. E. Siekhaus, and J. Toshima, “Rab5-mediated endosome formation is regulated at the trans-Golgi network,” Communications Biology, vol. 2, no. 1. Springer Nature, 2019.
[Published Version]
View
| Files available
| DOI
| WoS
2018 | Published | Journal Article | IST-REx-ID: 308 |

A. Ratheesh et al., “Drosophila TNF modulates tissue tension in the embryo to facilitate macrophage invasive migration,” Developmental Cell, vol. 45, no. 3. Elsevier, pp. 331–346, 2018.
[Published Version]
View
| Files available
| DOI
| Download Published Version (ext.)
| WoS
| PubMed | Europe PMC
2018 | Published | Journal Article | IST-REx-ID: 544 |

A. György et al., “Tools allowing independent visualization and genetic manipulation of Drosophila melanogaster macrophages and surrounding tissues,” G3: Genes, Genomes, Genetics, vol. 8, no. 3. Genetics Society of America, pp. 845–857, 2018.
[Published Version]
View
| Files available
| DOI
| WoS
2018 | Published | Journal Article | IST-REx-ID: 620 |

W. Yamamoto et al., “Distinct roles for plasma membrane PtdIns 4 P and PtdIns 4 5 P2 during yeast receptor mediated endocytosis,” Journal of Cell Science, vol. 131, no. 1. Company of Biologists, 2018.
[Published Version]
View
| DOI
| Download Published Version (ext.)
| WoS
| PubMed | Europe PMC
2017 | Published | Journal Article | IST-REx-ID: 751 |

Y. Matsubayashi et al., “A moving source of matrix components is essential for De Novo basement membrane formation,” Current Biology, vol. 27, no. 22. Cell Press, p. 3526–3534e.4, 2017.
[Published Version]
View
| Files available
| DOI
| WoS
2016 | Published | Journal Article | IST-REx-ID: 1475 |

J. Toshima et al., “Yeast Eps15-like endocytic protein Pan1p regulates the interaction between endocytic vesicles, endosomes and the actin cytoskeleton,” eLife, vol. 5, no. February 2016. eLife Sciences Publications, 2016.
[Published Version]
View
| Files available
| DOI
2016 | Published | Journal Article | IST-REx-ID: 1476 |

J. Toshima et al., “Srv2/CAP is required for polarized actin cable assembly and patch internalization during clathrin-mediated endocytosis,” Journal of Cell Science, vol. 129, no. 2. Company of Biologists, pp. 367–379, 2016.
[Published Version]
View
| Files available
| DOI
2015 | Published | Journal Article | IST-REx-ID: 1712 |

A. Ratheesh, V. Belyaeva, and D. E. Siekhaus, “Drosophila immune cell migration and adhesion during embryonic development and larval immune responses,” Current Opinion in Cell Biology, vol. 36, no. 10. Elsevier, pp. 71–79, 2015.
[Published Version]
View
| Files available
| DOI
2015 | Published | Journal Article | IST-REx-ID: 2025 |

D. Kawada et al., “The yeast Arf-GAP Glo3p is required for the endocytic recycling of cell surface proteins,” Biochimica et Biophysica Acta - Molecular Cell Research, vol. 1853, no. 1. Elsevier, pp. 144–156, 2015.
[Submitted Version]
View
| Files available
| DOI
2014 | Published | Journal Article | IST-REx-ID: 2024 |

J. Toshima et al., “Bifurcation of the endocytic pathway into Rab5-dependent and -independent transport to the vacuole,” Nature Communications, vol. 5. Nature Publishing Group, 2014.
[Submitted Version]
View
| Files available
| DOI
2010 | Published | Journal Article | IST-REx-ID: 3153
D. E. Siekhaus, M. Haesemeyer, O. Moffitt, and R. Lehmann, “RhoL controls invasion and Rap1 localization during immune cell transmigration in Drosophila,” Nature Cell Biology, vol. 12, no. 6. Nature Publishing Group, pp. 605–610, 2010.
View
| Download (ext.)
2003 | Published | Journal Article | IST-REx-ID: 3151
L. Rayburn et al., “Amontillado, the Drosophila homolog of the prohormone processing protease PC2, is required during embryogenesis and early larval development,” Genetics, vol. 163, no. 1. Genetics Society of America, pp. 227–237, 2003.
View
2000 | Published | Journal Article | IST-REx-ID: 3149 |

J. Hwang, D. E. Siekhaus, R. Fuller, P. Taghert, and I. Lindberg, “Interaction of Drosophila melanogaster prohormone convertase 2 and 7B2: Insect cell specific processing and secretion,” Journal of Biological Chemistry, vol. 275, no. 23. American Society for Biochemistry and Molecular Biology, pp. 17886–17893, 2000.
[Published Version]
View
| DOI
| Download Published Version (ext.)
| PubMed | Europe PMC
1999 | Published | Journal Article | IST-REx-ID: 3148 |

D. E. Siekhaus and R. Fuller, “A role for amontillado the Drosophila homolog of the neuropeptide precursor processing protease PC2 in triggering hatching behavior,” Journal of Neuroscience, vol. 19, no. 16. Society for Neuroscience, pp. 6942–6954, 1999.
[Published Version]
View
| DOI
| Download Published Version (ext.)
| PubMed | Europe PMC
Grants
30 Publications
2023 | Published | Journal Article | IST-REx-ID: 13316 |

J. Y. Toshima et al., “The yeast endocytic early/sorting compartment exists as an independent sub-compartment within the trans-Golgi network,” eLife, vol. 12. eLife Sciences Publications, 2023.
[Published Version]
View
| Files available
| DOI
| WoS
| PubMed | Europe PMC
2023 | Published | Journal Article | IST-REx-ID: 14316 |

M. Nagano, K. Aoshima, H. Shimamura, D. E. Siekhaus, J. Y. Toshima, and J. Toshima, “Distinct role of TGN-resident clathrin adaptors for Vps21p activation in the TGN-endosome trafficking pathway,” Journal of Cell Science, vol. 136, no. 17. The Company of Biologists, 2023.
[Preprint]
View
| DOI
| Download Preprint (ext.)
| PubMed | Europe PMC
2022 | Published | Journal Article | IST-REx-ID: 12080 |

M. Enshoji et al., “Eps15/Pan1p is a master regulator of the late stages of the endocytic pathway,” Journal of Cell Biology, vol. 221, no. 10. Rockefeller University Press, 2022.
[Published Version]
View
| Files available
| DOI
| WoS
| PubMed | Europe PMC
2022 | Published | Journal Article | IST-REx-ID: 10614 |

V. Belyaeva et al., “Fos regulates macrophage infiltration against surrounding tissue resistance by a cortical actin-based mechanism in Drosophila,” PLoS Biology, vol. 20, no. 1. Public Library of Science, p. e3001494, 2022.
[Published Version]
View
| Files available
| DOI
| WoS
| PubMed | Europe PMC
2022 | Published | Journal Article | IST-REx-ID: 10712 |

M. Roblek et al., “The solute carrier MFSD1 decreases β1 integrin’s activation status and thus tumor metastasis,” Frontiers in Oncology, vol. 12. Frontiers, 2022.
[Published Version]
View
| Files available
| DOI
| WoS
2022 | Published | Journal Article | IST-REx-ID: 10713 |

M. Akhmanova et al., “Cell division in tissues enables macrophage infiltration,” Science, vol. 376, no. 6591. American Association for the Advancement of Science, pp. 394–396, 2022.
[Preprint]
View
| DOI
| Download Preprint (ext.)
| WoS
| PubMed | Europe PMC
2022 | Published | Journal Article | IST-REx-ID: 10714 |

E. T. Martin et al., “A translation control module coordinates germline stem cell differentiation with ribosome biogenesis during Drosophila oogenesis,” Developmental Cell, vol. 57, no. 7. Elsevier, p. 883–900.e10, 2022.
[Preprint]
View
| DOI
| Download Preprint (ext.)
| WoS
2022 | Published | Journal Article | IST-REx-ID: 10918 |

S. Emtenani et al., “Macrophage mitochondrial bioenergetics and tissue invasion are boosted by an Atossa-Porthos axis in Drosophila,” The Embo Journal, vol. 41. Embo Press, 2022.
[Published Version]
View
| Files available
| DOI
| WoS
2021 | Published | Journal Article | IST-REx-ID: 9363 |

Á. Inglés Prieto et al., “Optogenetic delivery of trophic signals in a genetic model of Parkinson’s disease,” PLoS genetics, vol. 17, no. 4. Public Library of Science, p. e1009479, 2021.
[Published Version]
View
| Files available
| DOI
| WoS
2020 | Submitted | Preprint | IST-REx-ID: 8557 |

V. Belyaeva et al., “Cortical actin properties controlled by Drosophila Fos aid macrophage infiltration against surrounding tissue resistance,” bioRxiv. .
[Preprint]
View
| Files available
| DOI
| Download Preprint (ext.)
2020 | Published | Journal Article | IST-REx-ID: 7466 |

K. Kierdorf et al., “Muscle function and homeostasis require cytokine inhibition of AKT activity in Drosophila,” eLife, vol. 9. eLife Sciences Publications, 2020.
[Published Version]
View
| Files available
| DOI
| WoS
2019 | Published | Journal Article | IST-REx-ID: 8 |

G. Trébuchet et al., “The Repo homeodomain transcription factor suppresses hematopoiesis in Drosophila and preserves the glial fate,” Journal of Neuroscience, vol. 39, no. 2. Society for Neuroscience, pp. 238–255, 2019.
[Published Version]
View
| Files available
| DOI
| WoS
| PubMed | Europe PMC
2019 | Published | Journal Article | IST-REx-ID: 6187 |

K. Valosková et al., “A conserved major facilitator superfamily member orchestrates a subset of O-glycosylation to aid macrophage tissue invasion,” eLife, vol. 8. eLife Sciences Publications, 2019.
[Published Version]
View
| Files available
| DOI
| WoS
2019 | Published | Journal Article | IST-REx-ID: 7097 |

M. Nagano, J. Y. Toshima, D. E. Siekhaus, and J. Toshima, “Rab5-mediated endosome formation is regulated at the trans-Golgi network,” Communications Biology, vol. 2, no. 1. Springer Nature, 2019.
[Published Version]
View
| Files available
| DOI
| WoS
2018 | Published | Journal Article | IST-REx-ID: 308 |

A. Ratheesh et al., “Drosophila TNF modulates tissue tension in the embryo to facilitate macrophage invasive migration,” Developmental Cell, vol. 45, no. 3. Elsevier, pp. 331–346, 2018.
[Published Version]
View
| Files available
| DOI
| Download Published Version (ext.)
| WoS
| PubMed | Europe PMC
2018 | Published | Journal Article | IST-REx-ID: 544 |

A. György et al., “Tools allowing independent visualization and genetic manipulation of Drosophila melanogaster macrophages and surrounding tissues,” G3: Genes, Genomes, Genetics, vol. 8, no. 3. Genetics Society of America, pp. 845–857, 2018.
[Published Version]
View
| Files available
| DOI
| WoS
2018 | Published | Journal Article | IST-REx-ID: 620 |

W. Yamamoto et al., “Distinct roles for plasma membrane PtdIns 4 P and PtdIns 4 5 P2 during yeast receptor mediated endocytosis,” Journal of Cell Science, vol. 131, no. 1. Company of Biologists, 2018.
[Published Version]
View
| DOI
| Download Published Version (ext.)
| WoS
| PubMed | Europe PMC
2017 | Published | Journal Article | IST-REx-ID: 751 |

Y. Matsubayashi et al., “A moving source of matrix components is essential for De Novo basement membrane formation,” Current Biology, vol. 27, no. 22. Cell Press, p. 3526–3534e.4, 2017.
[Published Version]
View
| Files available
| DOI
| WoS
2016 | Published | Journal Article | IST-REx-ID: 1475 |

J. Toshima et al., “Yeast Eps15-like endocytic protein Pan1p regulates the interaction between endocytic vesicles, endosomes and the actin cytoskeleton,” eLife, vol. 5, no. February 2016. eLife Sciences Publications, 2016.
[Published Version]
View
| Files available
| DOI
2016 | Published | Journal Article | IST-REx-ID: 1476 |

J. Toshima et al., “Srv2/CAP is required for polarized actin cable assembly and patch internalization during clathrin-mediated endocytosis,” Journal of Cell Science, vol. 129, no. 2. Company of Biologists, pp. 367–379, 2016.
[Published Version]
View
| Files available
| DOI
2015 | Published | Journal Article | IST-REx-ID: 1712 |

A. Ratheesh, V. Belyaeva, and D. E. Siekhaus, “Drosophila immune cell migration and adhesion during embryonic development and larval immune responses,” Current Opinion in Cell Biology, vol. 36, no. 10. Elsevier, pp. 71–79, 2015.
[Published Version]
View
| Files available
| DOI
2015 | Published | Journal Article | IST-REx-ID: 2025 |

D. Kawada et al., “The yeast Arf-GAP Glo3p is required for the endocytic recycling of cell surface proteins,” Biochimica et Biophysica Acta - Molecular Cell Research, vol. 1853, no. 1. Elsevier, pp. 144–156, 2015.
[Submitted Version]
View
| Files available
| DOI
2014 | Published | Journal Article | IST-REx-ID: 2024 |

J. Toshima et al., “Bifurcation of the endocytic pathway into Rab5-dependent and -independent transport to the vacuole,” Nature Communications, vol. 5. Nature Publishing Group, 2014.
[Submitted Version]
View
| Files available
| DOI
2010 | Published | Journal Article | IST-REx-ID: 3153
D. E. Siekhaus, M. Haesemeyer, O. Moffitt, and R. Lehmann, “RhoL controls invasion and Rap1 localization during immune cell transmigration in Drosophila,” Nature Cell Biology, vol. 12, no. 6. Nature Publishing Group, pp. 605–610, 2010.
View
| Download (ext.)
2003 | Published | Journal Article | IST-REx-ID: 3151
L. Rayburn et al., “Amontillado, the Drosophila homolog of the prohormone processing protease PC2, is required during embryogenesis and early larval development,” Genetics, vol. 163, no. 1. Genetics Society of America, pp. 227–237, 2003.
View
2000 | Published | Journal Article | IST-REx-ID: 3149 |

J. Hwang, D. E. Siekhaus, R. Fuller, P. Taghert, and I. Lindberg, “Interaction of Drosophila melanogaster prohormone convertase 2 and 7B2: Insect cell specific processing and secretion,” Journal of Biological Chemistry, vol. 275, no. 23. American Society for Biochemistry and Molecular Biology, pp. 17886–17893, 2000.
[Published Version]
View
| DOI
| Download Published Version (ext.)
| PubMed | Europe PMC
1999 | Published | Journal Article | IST-REx-ID: 3148 |

D. E. Siekhaus and R. Fuller, “A role for amontillado the Drosophila homolog of the neuropeptide precursor processing protease PC2 in triggering hatching behavior,” Journal of Neuroscience, vol. 19, no. 16. Society for Neuroscience, pp. 6942–6954, 1999.
[Published Version]
View
| DOI
| Download Published Version (ext.)
| PubMed | Europe PMC