---
_id: '12115'
acknowledgement: This work was supported by European Commission’s Seventh Framework
  Programme under Grant Agreement No. 279113 (OCTIPS; www.octips.eu).
article_processing_charge: No
article_type: original
author:
- first_name: Jacek
  full_name: Glajzer, Jacek
  last_name: Glajzer
- first_name: Dan Cacsire
  full_name: Castillo-Tong, Dan Cacsire
  last_name: Castillo-Tong
- first_name: Rolf
  full_name: Richter, Rolf
  last_name: Richter
- first_name: Ignace
  full_name: Vergote, Ignace
  last_name: Vergote
- first_name: Hagen
  full_name: Kulbe, Hagen
  last_name: Kulbe
- first_name: Adriaan
  full_name: Vanderstichele, Adriaan
  last_name: Vanderstichele
- first_name: Ilary
  full_name: Ruscito, Ilary
  last_name: Ruscito
- first_name: Fabian
  full_name: Trillsch, Fabian
  last_name: Trillsch
- first_name: Alexander
  full_name: Mustea, Alexander
  last_name: Mustea
- first_name: Caroline
  full_name: Kreuzinger, Caroline
  id: 382077BA-F248-11E8-B48F-1D18A9856A87
  last_name: Kreuzinger
- first_name: Charlie
  full_name: Gourley, Charlie
  last_name: Gourley
- first_name: Hani
  full_name: Gabra, Hani
  last_name: Gabra
- first_name: Eliane T.
  full_name: Taube, Eliane T.
  last_name: Taube
- first_name: Oliver
  full_name: Dorigo, Oliver
  last_name: Dorigo
- first_name: David
  full_name: Horst, David
  last_name: Horst
- first_name: Carlotta
  full_name: Keunecke, Carlotta
  last_name: Keunecke
- first_name: Joanna
  full_name: Baum, Joanna
  last_name: Baum
- first_name: Timothy
  full_name: Angelotti, Timothy
  last_name: Angelotti
- first_name: Jalid
  full_name: Sehouli, Jalid
  last_name: Sehouli
- first_name: Elena Ioana
  full_name: Braicu, Elena Ioana
  last_name: Braicu
citation:
  ama: 'Glajzer J, Castillo-Tong DC, Richter R, et al. ASO Visual Abstract: Impact
    of BRCA mutation status on tumor dissemination pattern, surgical outcome, and
    patient survival in primary and recurrent high-grade serous ovarian cancer (HGSOC).
    A multicenter, retrospective study of the ovarian cancer therapy—innovative models
    prolong survival (OCTIPS) consortium. <i>Annals of Surgical Oncology</i>. 2023;30:46-47.
    doi:<a href="https://doi.org/10.1245/s10434-022-12681-z">10.1245/s10434-022-12681-z</a>'
  apa: 'Glajzer, J., Castillo-Tong, D. C., Richter, R., Vergote, I., Kulbe, H., Vanderstichele,
    A., … Braicu, E. I. (2023). ASO Visual Abstract: Impact of BRCA mutation status
    on tumor dissemination pattern, surgical outcome, and patient survival in primary
    and recurrent high-grade serous ovarian cancer (HGSOC). A multicenter, retrospective
    study of the ovarian cancer therapy—innovative models prolong survival (OCTIPS)
    consortium. <i>Annals of Surgical Oncology</i>. Springer Nature. <a href="https://doi.org/10.1245/s10434-022-12681-z">https://doi.org/10.1245/s10434-022-12681-z</a>'
  chicago: 'Glajzer, Jacek, Dan Cacsire Castillo-Tong, Rolf Richter, Ignace Vergote,
    Hagen Kulbe, Adriaan Vanderstichele, Ilary Ruscito, et al. “ASO Visual Abstract:
    Impact of BRCA Mutation Status on Tumor Dissemination Pattern, Surgical Outcome,
    and Patient Survival in Primary and Recurrent High-Grade Serous Ovarian Cancer
    (HGSOC). A Multicenter, Retrospective Study of the Ovarian Cancer Therapy—Innovative
    Models Prolong Survival (OCTIPS) Consortium.” <i>Annals of Surgical Oncology</i>.
    Springer Nature, 2023. <a href="https://doi.org/10.1245/s10434-022-12681-z">https://doi.org/10.1245/s10434-022-12681-z</a>.'
  ieee: 'J. Glajzer <i>et al.</i>, “ASO Visual Abstract: Impact of BRCA mutation status
    on tumor dissemination pattern, surgical outcome, and patient survival in primary
    and recurrent high-grade serous ovarian cancer (HGSOC). A multicenter, retrospective
    study of the ovarian cancer therapy—innovative models prolong survival (OCTIPS)
    consortium,” <i>Annals of Surgical Oncology</i>, vol. 30. Springer Nature, pp.
    46–47, 2023.'
  ista: 'Glajzer J, Castillo-Tong DC, Richter R, Vergote I, Kulbe H, Vanderstichele
    A, Ruscito I, Trillsch F, Mustea A, Kreuzinger C, Gourley C, Gabra H, Taube ET,
    Dorigo O, Horst D, Keunecke C, Baum J, Angelotti T, Sehouli J, Braicu EI. 2023.
    ASO Visual Abstract: Impact of BRCA mutation status on tumor dissemination pattern,
    surgical outcome, and patient survival in primary and recurrent high-grade serous
    ovarian cancer (HGSOC). A multicenter, retrospective study of the ovarian cancer
    therapy—innovative models prolong survival (OCTIPS) consortium. Annals of Surgical
    Oncology. 30, 46–47.'
  mla: 'Glajzer, Jacek, et al. “ASO Visual Abstract: Impact of BRCA Mutation Status
    on Tumor Dissemination Pattern, Surgical Outcome, and Patient Survival in Primary
    and Recurrent High-Grade Serous Ovarian Cancer (HGSOC). A Multicenter, Retrospective
    Study of the Ovarian Cancer Therapy—Innovative Models Prolong Survival (OCTIPS)
    Consortium.” <i>Annals of Surgical Oncology</i>, vol. 30, Springer Nature, 2023,
    pp. 46–47, doi:<a href="https://doi.org/10.1245/s10434-022-12681-z">10.1245/s10434-022-12681-z</a>.'
  short: J. Glajzer, D.C. Castillo-Tong, R. Richter, I. Vergote, H. Kulbe, A. Vanderstichele,
    I. Ruscito, F. Trillsch, A. Mustea, C. Kreuzinger, C. Gourley, H. Gabra, E.T.
    Taube, O. Dorigo, D. Horst, C. Keunecke, J. Baum, T. Angelotti, J. Sehouli, E.I.
    Braicu, Annals of Surgical Oncology 30 (2023) 46–47.
date_created: 2023-01-12T11:56:22Z
date_published: 2023-01-01T00:00:00Z
date_updated: 2023-09-05T15:18:36Z
day: '01'
department:
- _id: JoDa
doi: 10.1245/s10434-022-12681-z
external_id:
  isi:
  - '000879151800001'
intvolume: '        30'
isi: 1
keyword:
- Oncology
- Surgery
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1245/s10434-022-12681-z
month: '01'
oa: 1
oa_version: Published Version
page: 46-47
publication: Annals of Surgical Oncology
publication_identifier:
  eissn:
  - 1534-4681
  issn:
  - 1068-9265
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
  record:
  - id: '12205'
    relation: other
    status: public
scopus_import: '1'
status: public
title: 'ASO Visual Abstract: Impact of BRCA mutation status on tumor dissemination
  pattern, surgical outcome, and patient survival in primary and recurrent high-grade
  serous ovarian cancer (HGSOC). A multicenter, retrospective study of the ovarian
  cancer therapy—innovative models prolong survival (OCTIPS) consortium'
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 30
year: '2023'
...
---
_id: '12159'
abstract:
- lang: eng
  text: The term “haplotype block” is commonly used in the developing field of haplotype-based
    inference methods. We argue that the term should be defined based on the structure
    of the Ancestral Recombination Graph (ARG), which contains complete information
    on the ancestry of a sample. We use simulated examples to demonstrate key features
    of the relationship between haplotype blocks and ancestral structure, emphasizing
    the stochasticity of the processes that generate them. Even the simplest cases
    of neutrality or of a “hard” selective sweep produce a rich structure, often missed
    by commonly used statistics. We highlight a number of novel methods for inferring
    haplotype structure, based on the full ARG, or on a sequence of trees, and illustrate
    how they can be used to define haplotype blocks using an empirical data set. While
    the advent of new, computationally efficient methods makes it possible to apply
    these concepts broadly, they (and additional new methods) could benefit from adding
    features to explore haplotype blocks, as we define them. Understanding and applying
    the concept of the haplotype block will be essential to fully exploit long and
    linked-read sequencing technologies.
acknowledgement: 'We thank the Barton group for useful discussion and feedback during
  the writing of this article. Comments from Roger Butlin, Molly Schumer''s Group,
  the tskit development team, editors and three reviewers greatly improved the manuscript.
  Funding was provided by SCAS (Natural Sciences Programme, Knut and Alice Wallenberg
  Foundation), an FWF Wittgenstein grant (PT1001Z211), an FWF standalone grant (grant
  P 32166), and an ERC Advanced Grant. YFC was supported by the Max Planck Society
  and an ERC Proof of Concept Grant #101069216 (HAPLOTAGGING).'
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Daria
  full_name: Shipilina, Daria
  id: 428A94B0-F248-11E8-B48F-1D18A9856A87
  last_name: Shipilina
  orcid: 0000-0002-1145-9226
- first_name: Arka
  full_name: Pal, Arka
  id: 6AAB2240-CA9A-11E9-9C1A-D9D1E5697425
  last_name: Pal
  orcid: 0000-0002-4530-8469
- first_name: Sean
  full_name: Stankowski, Sean
  id: 43161670-5719-11EA-8025-FABC3DDC885E
  last_name: Stankowski
- first_name: Yingguang Frank
  full_name: Chan, Yingguang Frank
  last_name: Chan
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
citation:
  ama: Shipilina D, Pal A, Stankowski S, Chan YF, Barton NH. On the origin and structure
    of haplotype blocks. <i>Molecular Ecology</i>. 2023;32(6):1441-1457. doi:<a href="https://doi.org/10.1111/mec.16793">10.1111/mec.16793</a>
  apa: Shipilina, D., Pal, A., Stankowski, S., Chan, Y. F., &#38; Barton, N. H. (2023).
    On the origin and structure of haplotype blocks. <i>Molecular Ecology</i>. Wiley.
    <a href="https://doi.org/10.1111/mec.16793">https://doi.org/10.1111/mec.16793</a>
  chicago: Shipilina, Daria, Arka Pal, Sean Stankowski, Yingguang Frank Chan, and
    Nicholas H Barton. “On the Origin and Structure of Haplotype Blocks.” <i>Molecular
    Ecology</i>. Wiley, 2023. <a href="https://doi.org/10.1111/mec.16793">https://doi.org/10.1111/mec.16793</a>.
  ieee: D. Shipilina, A. Pal, S. Stankowski, Y. F. Chan, and N. H. Barton, “On the
    origin and structure of haplotype blocks,” <i>Molecular Ecology</i>, vol. 32,
    no. 6. Wiley, pp. 1441–1457, 2023.
  ista: Shipilina D, Pal A, Stankowski S, Chan YF, Barton NH. 2023. On the origin
    and structure of haplotype blocks. Molecular Ecology. 32(6), 1441–1457.
  mla: Shipilina, Daria, et al. “On the Origin and Structure of Haplotype Blocks.”
    <i>Molecular Ecology</i>, vol. 32, no. 6, Wiley, 2023, pp. 1441–57, doi:<a href="https://doi.org/10.1111/mec.16793">10.1111/mec.16793</a>.
  short: D. Shipilina, A. Pal, S. Stankowski, Y.F. Chan, N.H. Barton, Molecular Ecology
    32 (2023) 1441–1457.
date_created: 2023-01-12T12:09:17Z
date_published: 2023-03-01T00:00:00Z
date_updated: 2023-08-16T08:18:47Z
day: '01'
ddc:
- '570'
department:
- _id: NiBa
doi: 10.1111/mec.16793
external_id:
  isi:
  - '000900762000001'
  pmid:
  - '36433653'
file:
- access_level: open_access
  checksum: b10e0f8fa3dc4d72aaf77a557200978a
  content_type: application/pdf
  creator: dernst
  date_created: 2023-08-16T08:15:41Z
  date_updated: 2023-08-16T08:15:41Z
  file_id: '14062'
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  relation: main_file
  success: 1
file_date_updated: 2023-08-16T08:15:41Z
has_accepted_license: '1'
intvolume: '        32'
isi: 1
issue: '6'
keyword:
- Genetics
- Ecology
- Evolution
- Behavior and Systematics
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
page: 1441-1457
pmid: 1
project:
- _id: 05959E1C-7A3F-11EA-A408-12923DDC885E
  grant_number: P32166
  name: The maintenance of alternative adaptive peaks in snapdragons
- _id: 25F42A32-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: Z211
  name: The Wittgenstein Prize
- _id: bd6958e0-d553-11ed-ba76-86eba6a76c00
  grant_number: '101055327'
  name: Understanding the evolution of continuous genomes
publication: Molecular Ecology
publication_identifier:
  eissn:
  - 1365-294X
  issn:
  - 0962-1083
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: On the origin and structure of haplotype blocks
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 32
year: '2023'
...
---
_id: '12162'
abstract:
- lang: eng
  text: Homeostatic balance in the intestinal epithelium relies on a fast cellular
    turnover, which is coordinated by an intricate interplay between biochemical signalling,
    mechanical forces and organ geometry. We review recent modelling approaches that
    have been developed to understand different facets of this remarkable homeostatic
    equilibrium. Existing models offer different, albeit complementary, perspectives
    on the problem. First, biomechanical models aim to explain the local and global
    mechanical stresses driving cell renewal as well as tissue shape maintenance.
    Second, compartmental models provide insights into the conditions necessary to
    keep a constant flow of cells with well-defined ratios of cell types, and how
    perturbations can lead to an unbalance of relative compartment sizes. A third
    family of models address, at the cellular level, the nature and regulation of
    stem fate choices that are necessary to fuel cellular turnover. We also review
    how these different approaches are starting to be integrated together across scales,
    to provide quantitative predictions and new conceptual frameworks to think about
    the dynamics of cell renewal in complex tissues.
acknowledgement: "This work received funding from the ERC under the European Union’s
  Horizon 2020 research and innovation programme (grant agreement No. 851288 to E.H.).\r\nB.
  C-M wants to acknowledge the support of the field of excellence Complexity of Life,
  in Basic Research and Innovation of the University of Graz."
article_processing_charge: Yes (via OA deal)
article_type: review
author:
- first_name: Bernat
  full_name: Corominas-Murtra, Bernat
  id: 43BE2298-F248-11E8-B48F-1D18A9856A87
  last_name: Corominas-Murtra
  orcid: 0000-0001-9806-5643
- first_name: Edouard B
  full_name: Hannezo, Edouard B
  id: 3A9DB764-F248-11E8-B48F-1D18A9856A87
  last_name: Hannezo
  orcid: 0000-0001-6005-1561
citation:
  ama: Corominas-Murtra B, Hannezo EB. Modelling the dynamics of mammalian gut homeostasis.
    <i>Seminars in Cell &#38; Developmental Biology</i>. 2023;150-151:58-65. doi:<a
    href="https://doi.org/10.1016/j.semcdb.2022.11.005">10.1016/j.semcdb.2022.11.005</a>
  apa: Corominas-Murtra, B., &#38; Hannezo, E. B. (2023). Modelling the dynamics of
    mammalian gut homeostasis. <i>Seminars in Cell &#38; Developmental Biology</i>.
    Elsevier. <a href="https://doi.org/10.1016/j.semcdb.2022.11.005">https://doi.org/10.1016/j.semcdb.2022.11.005</a>
  chicago: Corominas-Murtra, Bernat, and Edouard B Hannezo. “Modelling the Dynamics
    of Mammalian Gut Homeostasis.” <i>Seminars in Cell &#38; Developmental Biology</i>.
    Elsevier, 2023. <a href="https://doi.org/10.1016/j.semcdb.2022.11.005">https://doi.org/10.1016/j.semcdb.2022.11.005</a>.
  ieee: B. Corominas-Murtra and E. B. Hannezo, “Modelling the dynamics of mammalian
    gut homeostasis,” <i>Seminars in Cell &#38; Developmental Biology</i>, vol. 150–151.
    Elsevier, pp. 58–65, 2023.
  ista: Corominas-Murtra B, Hannezo EB. 2023. Modelling the dynamics of mammalian
    gut homeostasis. Seminars in Cell &#38; Developmental Biology. 150–151, 58–65.
  mla: Corominas-Murtra, Bernat, and Edouard B. Hannezo. “Modelling the Dynamics of
    Mammalian Gut Homeostasis.” <i>Seminars in Cell &#38; Developmental Biology</i>,
    vol. 150–151, Elsevier, 2023, pp. 58–65, doi:<a href="https://doi.org/10.1016/j.semcdb.2022.11.005">10.1016/j.semcdb.2022.11.005</a>.
  short: B. Corominas-Murtra, E.B. Hannezo, Seminars in Cell &#38; Developmental Biology
    150–151 (2023) 58–65.
date_created: 2023-01-12T12:09:47Z
date_published: 2023-12-02T00:00:00Z
date_updated: 2024-01-16T13:22:32Z
day: '02'
ddc:
- '570'
department:
- _id: EdHa
doi: 10.1016/j.semcdb.2022.11.005
ec_funded: 1
external_id:
  isi:
  - '001053522200001'
  pmid:
  - '36470715'
file:
- access_level: open_access
  checksum: c619887cf130f4649bf3035417186004
  content_type: application/pdf
  creator: dernst
  date_created: 2024-01-08T10:16:04Z
  date_updated: 2024-01-08T10:16:04Z
  file_id: '14741'
  file_name: 2023_SeminarsCellDevBiology_CorominasMurtra.pdf
  file_size: 1343750
  relation: main_file
  success: 1
file_date_updated: 2024-01-08T10:16:04Z
has_accepted_license: '1'
isi: 1
keyword:
- Cell Biology
- Developmental Biology
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
page: 58-65
pmid: 1
project:
- _id: 05943252-7A3F-11EA-A408-12923DDC885E
  call_identifier: H2020
  grant_number: '851288'
  name: Design Principles of Branching Morphogenesis
publication: Seminars in Cell & Developmental Biology
publication_identifier:
  issn:
  - 1084-9521
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Modelling the dynamics of mammalian gut homeostasis
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 150-151
year: '2023'
...
---
_id: '12163'
abstract:
- lang: eng
  text: Small GTPases play essential roles in the organization of eukaryotic cells.
    In recent years, it has become clear that their intracellular functions result
    from intricate biochemical networks of the GTPase and their regulators that dynamically
    bind to a membrane surface. Due to the inherent complexities of their interactions,
    however, revealing the underlying mechanisms of action is often difficult to achieve
    from in vivo studies. This review summarizes in vitro reconstitution approaches
    developed to obtain a better mechanistic understanding of how small GTPase activities
    are regulated in space and time.
acknowledgement: The authors acknowledge support from IST Austria and helpful comments
  from the anonymous reviewers that helped to improve this manuscript. We apologize
  to the authors of primary literature and outstanding research not cited here due
  to space restraints.
article_processing_charge: Yes (via OA deal)
article_type: review
author:
- first_name: Martin
  full_name: Loose, Martin
  id: 462D4284-F248-11E8-B48F-1D18A9856A87
  last_name: Loose
  orcid: 0000-0001-7309-9724
- first_name: Albert
  full_name: Auer, Albert
  id: 3018E8C2-F248-11E8-B48F-1D18A9856A87
  last_name: Auer
  orcid: 0000-0002-3580-2906
- first_name: Gabriel
  full_name: Brognara, Gabriel
  id: D96FFDA0-A884-11E9-9968-DC26E6697425
  last_name: Brognara
- first_name: Hanifatul R
  full_name: Budiman, Hanifatul R
  id: 55380f95-15b2-11ec-abd3-aff8e230696b
  last_name: Budiman
- first_name: Lukasz M
  full_name: Kowalski, Lukasz M
  id: e3a512e2-4bbe-11eb-a68a-e3857a7844c2
  last_name: Kowalski
- first_name: Ivana
  full_name: Matijevic, Ivana
  id: 83c17ce3-15b2-11ec-abd3-f486545870bd
  last_name: Matijevic
citation:
  ama: Loose M, Auer A, Brognara G, Budiman HR, Kowalski LM, Matijevic I. In vitro
    reconstitution of small GTPase regulation. <i>FEBS Letters</i>. 2023;597(6):762-777.
    doi:<a href="https://doi.org/10.1002/1873-3468.14540">10.1002/1873-3468.14540</a>
  apa: Loose, M., Auer, A., Brognara, G., Budiman, H. R., Kowalski, L. M., &#38; Matijevic,
    I. (2023). In vitro reconstitution of small GTPase regulation. <i>FEBS Letters</i>.
    Wiley. <a href="https://doi.org/10.1002/1873-3468.14540">https://doi.org/10.1002/1873-3468.14540</a>
  chicago: Loose, Martin, Albert Auer, Gabriel Brognara, Hanifatul R Budiman, Lukasz
    M Kowalski, and Ivana Matijevic. “In Vitro Reconstitution of Small GTPase Regulation.”
    <i>FEBS Letters</i>. Wiley, 2023. <a href="https://doi.org/10.1002/1873-3468.14540">https://doi.org/10.1002/1873-3468.14540</a>.
  ieee: M. Loose, A. Auer, G. Brognara, H. R. Budiman, L. M. Kowalski, and I. Matijevic,
    “In vitro reconstitution of small GTPase regulation,” <i>FEBS Letters</i>, vol.
    597, no. 6. Wiley, pp. 762–777, 2023.
  ista: Loose M, Auer A, Brognara G, Budiman HR, Kowalski LM, Matijevic I. 2023. In
    vitro reconstitution of small GTPase regulation. FEBS Letters. 597(6), 762–777.
  mla: Loose, Martin, et al. “In Vitro Reconstitution of Small GTPase Regulation.”
    <i>FEBS Letters</i>, vol. 597, no. 6, Wiley, 2023, pp. 762–77, doi:<a href="https://doi.org/10.1002/1873-3468.14540">10.1002/1873-3468.14540</a>.
  short: M. Loose, A. Auer, G. Brognara, H.R. Budiman, L.M. Kowalski, I. Matijevic,
    FEBS Letters 597 (2023) 762–777.
date_created: 2023-01-12T12:09:58Z
date_published: 2023-03-01T00:00:00Z
date_updated: 2023-08-16T08:32:29Z
day: '01'
ddc:
- '570'
department:
- _id: MaLo
doi: 10.1002/1873-3468.14540
external_id:
  isi:
  - '000891573000001'
  pmid:
  - '36448231'
file:
- access_level: open_access
  checksum: 7492244d3f9c5faa1347ef03f6e5bc84
  content_type: application/pdf
  creator: dernst
  date_created: 2023-08-16T08:31:04Z
  date_updated: 2023-08-16T08:31:04Z
  file_id: '14063'
  file_name: 2023_FEBSLetters_Loose.pdf
  file_size: 3148143
  relation: main_file
  success: 1
file_date_updated: 2023-08-16T08:31:04Z
has_accepted_license: '1'
intvolume: '       597'
isi: 1
issue: '6'
keyword:
- Cell Biology
- Genetics
- Molecular Biology
- Biochemistry
- Structural Biology
- Biophysics
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
page: 762-777
pmid: 1
publication: FEBS Letters
publication_identifier:
  eissn:
  - 1873-3468
  issn:
  - 0014-5793
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: In vitro reconstitution of small GTPase regulation
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 597
year: '2023'
...
---
_id: '12164'
abstract:
- lang: eng
  text: 'A shared-memory counter is a widely-used and well-studied concurrent object.
    It supports two operations: An Inc operation that increases its value by 1 and
    a Read operation that returns its current value. In Jayanti et al (SIAM J Comput,
    30(2), 2000), Jayanti, Tan and Toueg proved a linear lower bound on the worst-case
    step complexity of obstruction-free implementations, from read-write registers,
    of a large class of shared objects that includes counters. The lower bound leaves
    open the question of finding counter implementations with sub-linear amortized
    step complexity. In this work, we address this gap. We show that n-process, wait-free
    and linearizable counters can be implemented from read-write registers with O(log2n)
    amortized step complexity. This is the first counter algorithm from read-write
    registers that provides sub-linear amortized step complexity in executions of
    arbitrary length. Since a logarithmic lower bound on the amortized step complexity
    of obstruction-free counter implementations exists, our upper bound is within
    a logarithmic factor of the optimal. The worst-case step complexity of the construction
    remains linear, which is optimal. This is obtained thanks to a new max register
    construction with O(logn) amortized step complexity in executions of arbitrary
    length in which the value stored in the register does not grow too quickly. We
    then leverage an existing counter algorithm by Aspnes, Attiya and Censor-Hillel
    [1] in which we “plug” our max register implementation to show that it remains
    linearizable while achieving O(log2n) amortized step complexity.'
acknowledgement: A preliminary version of this work appeared in DISC’19. Mirza Ahad
  Baig, Alessia Milani and Corentin Travers are supported by ANR projects Descartes
  and FREDDA. Mirza Ahad Baig is supported by UMI Relax. Danny Hendler is supported
  by the Israel Science Foundation (Grants 380/18 and 1425/22).
article_processing_charge: No
article_type: original
author:
- first_name: Mirza Ahad
  full_name: Baig, Mirza Ahad
  id: 3EDE6DE4-AA5A-11E9-986D-341CE6697425
  last_name: Baig
- first_name: Danny
  full_name: Hendler, Danny
  last_name: Hendler
- first_name: Alessia
  full_name: Milani, Alessia
  last_name: Milani
- first_name: Corentin
  full_name: Travers, Corentin
  last_name: Travers
citation:
  ama: Baig MA, Hendler D, Milani A, Travers C. Long-lived counters with polylogarithmic
    amortized step complexity. <i>Distributed Computing</i>. 2023;36:29-43. doi:<a
    href="https://doi.org/10.1007/s00446-022-00439-5">10.1007/s00446-022-00439-5</a>
  apa: Baig, M. A., Hendler, D., Milani, A., &#38; Travers, C. (2023). Long-lived
    counters with polylogarithmic amortized step complexity. <i>Distributed Computing</i>.
    Springer Nature. <a href="https://doi.org/10.1007/s00446-022-00439-5">https://doi.org/10.1007/s00446-022-00439-5</a>
  chicago: Baig, Mirza Ahad, Danny Hendler, Alessia Milani, and Corentin Travers.
    “Long-Lived Counters with Polylogarithmic Amortized Step Complexity.” <i>Distributed
    Computing</i>. Springer Nature, 2023. <a href="https://doi.org/10.1007/s00446-022-00439-5">https://doi.org/10.1007/s00446-022-00439-5</a>.
  ieee: M. A. Baig, D. Hendler, A. Milani, and C. Travers, “Long-lived counters with
    polylogarithmic amortized step complexity,” <i>Distributed Computing</i>, vol.
    36. Springer Nature, pp. 29–43, 2023.
  ista: Baig MA, Hendler D, Milani A, Travers C. 2023. Long-lived counters with polylogarithmic
    amortized step complexity. Distributed Computing. 36, 29–43.
  mla: Baig, Mirza Ahad, et al. “Long-Lived Counters with Polylogarithmic Amortized
    Step Complexity.” <i>Distributed Computing</i>, vol. 36, Springer Nature, 2023,
    pp. 29–43, doi:<a href="https://doi.org/10.1007/s00446-022-00439-5">10.1007/s00446-022-00439-5</a>.
  short: M.A. Baig, D. Hendler, A. Milani, C. Travers, Distributed Computing 36 (2023)
    29–43.
date_created: 2023-01-12T12:10:08Z
date_published: 2023-03-01T00:00:00Z
date_updated: 2023-08-16T08:39:36Z
day: '01'
department:
- _id: KrPi
doi: 10.1007/s00446-022-00439-5
external_id:
  isi:
  - '000890138700001'
intvolume: '        36'
isi: 1
keyword:
- Computational Theory and Mathematics
- Computer Networks and Communications
- Hardware and Architecture
- Theoretical Computer Science
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://drops.dagstuhl.de/opus/volltexte/2019/11310/
month: '03'
oa: 1
oa_version: Preprint
page: 29-43
publication: Distributed Computing
publication_identifier:
  eissn:
  - 1432-0452
  issn:
  - 0178-2770
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Long-lived counters with polylogarithmic amortized step complexity
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 36
year: '2023'
...
---
_id: '12165'
abstract:
- lang: eng
  text: It may come as a surprise that a phenomenon as ubiquitous and prominent as
    the transition from laminar to turbulent flow has resisted combined efforts by
    physicists, engineers and mathematicians, and remained unresolved for almost one
    and a half centuries. In recent years, various studies have proposed analogies
    to directed percolation, a well-known universality class in statistical mechanics,
    which describes a non-equilibrium phase transition from a fluctuating active phase
    into an absorbing state. It is this unlikely relation between the multiscale,
    high-dimensional dynamics that signify the transition process in virtually all
    flows of practical relevance, and the arguably most basic non-equilibrium phase
    transition, that so far has mainly been the subject of model studies, which I
    review in this Perspective.
article_processing_charge: No
article_type: original
author:
- first_name: Björn
  full_name: Hof, Björn
  id: 3A374330-F248-11E8-B48F-1D18A9856A87
  last_name: Hof
  orcid: 0000-0003-2057-2754
citation:
  ama: Hof B. Directed percolation and the transition to turbulence. <i>Nature Reviews
    Physics</i>. 2023;5:62-72. doi:<a href="https://doi.org/10.1038/s42254-022-00539-y">10.1038/s42254-022-00539-y</a>
  apa: Hof, B. (2023). Directed percolation and the transition to turbulence. <i>Nature
    Reviews Physics</i>. Springer Nature. <a href="https://doi.org/10.1038/s42254-022-00539-y">https://doi.org/10.1038/s42254-022-00539-y</a>
  chicago: Hof, Björn. “Directed Percolation and the Transition to Turbulence.” <i>Nature
    Reviews Physics</i>. Springer Nature, 2023. <a href="https://doi.org/10.1038/s42254-022-00539-y">https://doi.org/10.1038/s42254-022-00539-y</a>.
  ieee: B. Hof, “Directed percolation and the transition to turbulence,” <i>Nature
    Reviews Physics</i>, vol. 5. Springer Nature, pp. 62–72, 2023.
  ista: Hof B. 2023. Directed percolation and the transition to turbulence. Nature
    Reviews Physics. 5, 62–72.
  mla: Hof, Björn. “Directed Percolation and the Transition to Turbulence.” <i>Nature
    Reviews Physics</i>, vol. 5, Springer Nature, 2023, pp. 62–72, doi:<a href="https://doi.org/10.1038/s42254-022-00539-y">10.1038/s42254-022-00539-y</a>.
  short: B. Hof, Nature Reviews Physics 5 (2023) 62–72.
date_created: 2023-01-12T12:10:18Z
date_published: 2023-01-01T00:00:00Z
date_updated: 2023-08-01T12:50:48Z
day: '01'
department:
- _id: BjHo
doi: 10.1038/s42254-022-00539-y
external_id:
  isi:
  - '000890148700002'
intvolume: '         5'
isi: 1
keyword:
- General Physics and Astronomy
language:
- iso: eng
month: '01'
oa_version: None
page: 62-72
publication: Nature Reviews Physics
publication_identifier:
  eissn:
  - 2522-5820
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Directed percolation and the transition to turbulence
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 5
year: '2023'
...
---
_id: '12172'
abstract:
- lang: eng
  text: In industrial reactors and equipment, non-ideality is quite a common phenomenon
    rather than an exception. These deviations from ideality impact the process's
    overall efficiency and the effectiveness of the equipment. To recognize the associated
    non-ideality, one needs to have enough understanding of the formulation of the
    equations and in-depth knowledge of the residence time distribution (RTD) data
    of real reactors. In the current work, step input and pulse input were used to
    create RTD data for Cascade continuous stirred tank reactors (CSTRs). For the
    aforementioned configuration, experiments were run at various flow rates to validate
    the developed characteristic equations. To produce RTD data, distilled water was
    utilized as the flowing fluid, and NaOH was the tracer substance. The ideal behavior
    of tracer concentration exits age distribution, and cumulative fraction for each
    setup and each input was plotted and experimental results were compared with perfect
    behavior. Deviation of concentration exit age distribution and cumulative fractional
    distribution from ideal behavior is more in pulse input as compared to a step
    input. For ideal cases, the exit age distribution curve and cumulative fraction
    curves are independent of the type of input. But a significant difference was
    observed for the two cases, which may be due to non-measurable fluctuations in
    volumetric flow rate, non-achievement of instant injection of tracer in case of
    pulse input, and slight variations in the sampling period. Further, with increasing
    flow rate, concentration, exit age, and cumulative fractional curves shifted upward,
    and this behavior matches with the actual case.
article_processing_charge: No
article_type: original
author:
- first_name: Bushra
  full_name: Khatoon, Bushra
  last_name: Khatoon
- first_name: Shoaib
  full_name: Kamil, Shoaib
  id: 185a19af-dc7d-11ea-9b2f-8eb2201959e9
  last_name: Kamil
- first_name: Hitesh
  full_name: Babu, Hitesh
  last_name: Babu
- first_name: M.
  full_name: Siraj Alam, M.
  last_name: Siraj Alam
citation:
  ama: 'Khatoon B, Kamil S, Babu H, Siraj Alam M. Experimental analysis of Cascade
    CSTRs with step and pulse inputs. <i>Materials Today: Proceedings</i>. 2023;78(Part
    1):40-47. doi:<a href="https://doi.org/10.1016/j.matpr.2022.11.037">10.1016/j.matpr.2022.11.037</a>'
  apa: 'Khatoon, B., Kamil, S., Babu, H., &#38; Siraj Alam, M. (2023). Experimental
    analysis of Cascade CSTRs with step and pulse inputs. <i>Materials Today: Proceedings</i>.
    Elsevier. <a href="https://doi.org/10.1016/j.matpr.2022.11.037">https://doi.org/10.1016/j.matpr.2022.11.037</a>'
  chicago: 'Khatoon, Bushra, Shoaib Kamil, Hitesh Babu, and M. Siraj Alam. “Experimental
    Analysis of Cascade CSTRs with Step and Pulse Inputs.” <i>Materials Today: Proceedings</i>.
    Elsevier, 2023. <a href="https://doi.org/10.1016/j.matpr.2022.11.037">https://doi.org/10.1016/j.matpr.2022.11.037</a>.'
  ieee: 'B. Khatoon, S. Kamil, H. Babu, and M. Siraj Alam, “Experimental analysis
    of Cascade CSTRs with step and pulse inputs,” <i>Materials Today: Proceedings</i>,
    vol. 78, no. Part 1. Elsevier, pp. 40–47, 2023.'
  ista: 'Khatoon B, Kamil S, Babu H, Siraj Alam M. 2023. Experimental analysis of
    Cascade CSTRs with step and pulse inputs. Materials Today: Proceedings. 78(Part
    1), 40–47.'
  mla: 'Khatoon, Bushra, et al. “Experimental Analysis of Cascade CSTRs with Step
    and Pulse Inputs.” <i>Materials Today: Proceedings</i>, vol. 78, no. Part 1, Elsevier,
    2023, pp. 40–47, doi:<a href="https://doi.org/10.1016/j.matpr.2022.11.037">10.1016/j.matpr.2022.11.037</a>.'
  short: 'B. Khatoon, S. Kamil, H. Babu, M. Siraj Alam, Materials Today: Proceedings
    78 (2023) 40–47.'
date_created: 2023-01-12T12:11:26Z
date_published: 2023-03-20T00:00:00Z
date_updated: 2023-08-16T09:08:11Z
day: '20'
department:
- _id: BjHo
doi: 10.1016/j.matpr.2022.11.037
intvolume: '        78'
issue: Part 1
keyword:
- General Medicine
language:
- iso: eng
month: '03'
oa_version: None
page: 40-47
publication: 'Materials Today: Proceedings'
publication_identifier:
  issn:
  - 2214-7853
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Experimental analysis of Cascade CSTRs with step and pulse inputs
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 78
year: '2023'
...
---
_id: '12183'
abstract:
- lang: eng
  text: We consider a gas of n bosonic particles confined in a box [−ℓ/2,ℓ/2]3 with
    Neumann boundary conditions. We prove Bose–Einstein condensation in the Gross–Pitaevskii
    regime, with an optimal bound on the condensate depletion. Moreover, our lower
    bound for the ground state energy in a small box [−ℓ/2,ℓ/2]3 implies (via Neumann
    bracketing) a lower bound for the ground state energy of N bosons in a large box
    [−L/2,L/2]3 with density ρ=N/L3 in the thermodynamic limit.
acknowledgement: Funding from the European Union’s Horizon 2020 research and innovation
  programme under the ERC grant agreement No 694227 is gratefully acknowledged.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Chiara
  full_name: Boccato, Chiara
  id: 342E7E22-F248-11E8-B48F-1D18A9856A87
  last_name: Boccato
- first_name: Robert
  full_name: Seiringer, Robert
  id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
  last_name: Seiringer
  orcid: 0000-0002-6781-0521
citation:
  ama: Boccato C, Seiringer R. The Bose Gas in a box with Neumann boundary conditions.
    <i>Annales Henri Poincare</i>. 2023;24:1505-1560. doi:<a href="https://doi.org/10.1007/s00023-022-01252-3">10.1007/s00023-022-01252-3</a>
  apa: Boccato, C., &#38; Seiringer, R. (2023). The Bose Gas in a box with Neumann
    boundary conditions. <i>Annales Henri Poincare</i>. Springer Nature. <a href="https://doi.org/10.1007/s00023-022-01252-3">https://doi.org/10.1007/s00023-022-01252-3</a>
  chicago: Boccato, Chiara, and Robert Seiringer. “The Bose Gas in a Box with Neumann
    Boundary Conditions.” <i>Annales Henri Poincare</i>. Springer Nature, 2023. <a
    href="https://doi.org/10.1007/s00023-022-01252-3">https://doi.org/10.1007/s00023-022-01252-3</a>.
  ieee: C. Boccato and R. Seiringer, “The Bose Gas in a box with Neumann boundary
    conditions,” <i>Annales Henri Poincare</i>, vol. 24. Springer Nature, pp. 1505–1560,
    2023.
  ista: Boccato C, Seiringer R. 2023. The Bose Gas in a box with Neumann boundary
    conditions. Annales Henri Poincare. 24, 1505–1560.
  mla: Boccato, Chiara, and Robert Seiringer. “The Bose Gas in a Box with Neumann
    Boundary Conditions.” <i>Annales Henri Poincare</i>, vol. 24, Springer Nature,
    2023, pp. 1505–60, doi:<a href="https://doi.org/10.1007/s00023-022-01252-3">10.1007/s00023-022-01252-3</a>.
  short: C. Boccato, R. Seiringer, Annales Henri Poincare 24 (2023) 1505–1560.
date_created: 2023-01-15T23:00:52Z
date_published: 2023-05-01T00:00:00Z
date_updated: 2023-08-16T11:34:03Z
day: '01'
department:
- _id: RoSe
doi: 10.1007/s00023-022-01252-3
ec_funded: 1
external_id:
  arxiv:
  - '2205.15284'
  isi:
  - '000910751800002'
intvolume: '        24'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2205.15284
month: '05'
oa: 1
oa_version: Preprint
page: 1505-1560
project:
- _id: 25C6DC12-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '694227'
  name: Analysis of quantum many-body systems
publication: Annales Henri Poincare
publication_identifier:
  issn:
  - 1424-0637
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: The Bose Gas in a box with Neumann boundary conditions
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 24
year: '2023'
...
---
_id: '12205'
abstract:
- lang: eng
  text: "Background: This study seeks to evaluate the impact of breast cancer (BRCA)
    gene status on tumor dissemination pattern, surgical outcome and survival in a
    multicenter cohort of paired primary ovarian cancer (pOC) and recurrent ovarian
    cancer (rOC).\r\n\r\nPatients and Methods: Medical records and follow-up data
    from 190 patients were gathered retrospectively. All patients had surgery at pOC
    and at least one further rOC surgery at four European high-volume centers. Patients
    were divided into one cohort with confirmed mutation for BRCA1 and/or BRCA2 (BRCAmut)
    and a second cohort with BRCA wild type or unknown (BRCAwt). Patterns of tumor
    presentation, surgical outcome and survival data were analyzed between the two
    groups.\r\n\r\nResults: Patients with BRCAmut disease were on average 4 years
    younger and had significantly more tumor involvement upon diagnosis. Patients
    with BRCAmut disease showed higher debulking rates at all stages. Multivariate
    analysis showed that only patient age had significant predictive value for complete
    tumor resection in pOC. At rOC, however, only BRCAmut status significantly correlated
    with optimal debulking. Patients with BRCAmut disease showed significantly prolonged
    overall survival (OS) by 24.3 months. Progression-free survival (PFS) was prolonged
    in the BRCAmut group at all stages as well, reaching statistical significance
    during recurrence.\r\n\r\nConclusions: Patients with BRCAmut disease showed a
    more aggressive course of disease with earlier onset and more extensive tumor
    dissemination at pOC. However, surgical outcome and OS were significantly better
    in patients with BRCAmut disease compared with patients with BRCAwt disease. We
    therefore propose to consider BRCAmut status in regard to patient selection for
    cytoreductive surgery, especially in rOC."
acknowledgement: "E.I.B. is a Feodor Lynen fellow of the Humboldt Foundation and a
  participant of the Charité Clinical Scientist Program funded by the Charité Universitätsmedizin
  Berlin and the Berlin Institute of Health. This work was supported by European Commission’s
  Seventh Framework Programme under grant agreement no. 279113 (OCTIPS; www.octips.eu).\r\nOpen
  Access funding enabled and organized by Projekt DEAL."
article_processing_charge: No
article_type: original
author:
- first_name: Jacek
  full_name: Glajzer, Jacek
  last_name: Glajzer
- first_name: Dan Cacsire
  full_name: Castillo-Tong, Dan Cacsire
  last_name: Castillo-Tong
- first_name: Rolf
  full_name: Richter, Rolf
  last_name: Richter
- first_name: Ignace
  full_name: Vergote, Ignace
  last_name: Vergote
- first_name: Hagen
  full_name: Kulbe, Hagen
  last_name: Kulbe
- first_name: Adriaan
  full_name: Vanderstichele, Adriaan
  last_name: Vanderstichele
- first_name: Ilary
  full_name: Ruscito, Ilary
  last_name: Ruscito
- first_name: Fabian
  full_name: Trillsch, Fabian
  last_name: Trillsch
- first_name: Alexander
  full_name: Mustea, Alexander
  last_name: Mustea
- first_name: Caroline
  full_name: Kreuzinger, Caroline
  id: 382077BA-F248-11E8-B48F-1D18A9856A87
  last_name: Kreuzinger
- first_name: Charlie
  full_name: Gourley, Charlie
  last_name: Gourley
- first_name: Hani
  full_name: Gabra, Hani
  last_name: Gabra
- first_name: Eliane T.
  full_name: Taube, Eliane T.
  last_name: Taube
- first_name: Oliver
  full_name: Dorigo, Oliver
  last_name: Dorigo
- first_name: David
  full_name: Horst, David
  last_name: Horst
- first_name: Carlotta
  full_name: Keunecke, Carlotta
  last_name: Keunecke
- first_name: Joanna
  full_name: Baum, Joanna
  last_name: Baum
- first_name: Timothy
  full_name: Angelotti, Timothy
  last_name: Angelotti
- first_name: Jalid
  full_name: Sehouli, Jalid
  last_name: Sehouli
- first_name: Elena Ioana
  full_name: Braicu, Elena Ioana
  last_name: Braicu
citation:
  ama: 'Glajzer J, Castillo-Tong DC, Richter R, et al. Impact of BRCA mutation status
    on tumor dissemination pattern, surgical outcome and patient survival in primary
    and recurrent high-grade serous ovarian cancer: A multicenter retrospective study
    by the Ovarian Cancer Therapy-Innovative Models Prolong Survival (OCTIPS) consortium.
    <i>Annals of Surgical Oncology</i>. 2023;30:35-45. doi:<a href="https://doi.org/10.1245/s10434-022-12459-3">10.1245/s10434-022-12459-3</a>'
  apa: 'Glajzer, J., Castillo-Tong, D. C., Richter, R., Vergote, I., Kulbe, H., Vanderstichele,
    A., … Braicu, E. I. (2023). Impact of BRCA mutation status on tumor dissemination
    pattern, surgical outcome and patient survival in primary and recurrent high-grade
    serous ovarian cancer: A multicenter retrospective study by the Ovarian Cancer
    Therapy-Innovative Models Prolong Survival (OCTIPS) consortium. <i>Annals of Surgical
    Oncology</i>. Springer Nature. <a href="https://doi.org/10.1245/s10434-022-12459-3">https://doi.org/10.1245/s10434-022-12459-3</a>'
  chicago: 'Glajzer, Jacek, Dan Cacsire Castillo-Tong, Rolf Richter, Ignace Vergote,
    Hagen Kulbe, Adriaan Vanderstichele, Ilary Ruscito, et al. “Impact of BRCA Mutation
    Status on Tumor Dissemination Pattern, Surgical Outcome and Patient Survival in
    Primary and Recurrent High-Grade Serous Ovarian Cancer: A Multicenter Retrospective
    Study by the Ovarian Cancer Therapy-Innovative Models Prolong Survival (OCTIPS) Consortium.”
    <i>Annals of Surgical Oncology</i>. Springer Nature, 2023. <a href="https://doi.org/10.1245/s10434-022-12459-3">https://doi.org/10.1245/s10434-022-12459-3</a>.'
  ieee: 'J. Glajzer <i>et al.</i>, “Impact of BRCA mutation status on tumor dissemination
    pattern, surgical outcome and patient survival in primary and recurrent high-grade
    serous ovarian cancer: A multicenter retrospective study by the Ovarian Cancer
    Therapy-Innovative Models Prolong Survival (OCTIPS) consortium,” <i>Annals of
    Surgical Oncology</i>, vol. 30. Springer Nature, pp. 35–45, 2023.'
  ista: 'Glajzer J, Castillo-Tong DC, Richter R, Vergote I, Kulbe H, Vanderstichele
    A, Ruscito I, Trillsch F, Mustea A, Kreuzinger C, Gourley C, Gabra H, Taube ET,
    Dorigo O, Horst D, Keunecke C, Baum J, Angelotti T, Sehouli J, Braicu EI. 2023.
    Impact of BRCA mutation status on tumor dissemination pattern, surgical outcome
    and patient survival in primary and recurrent high-grade serous ovarian cancer:
    A multicenter retrospective study by the Ovarian Cancer Therapy-Innovative Models
    Prolong Survival (OCTIPS) consortium. Annals of Surgical Oncology. 30, 35–45.'
  mla: 'Glajzer, Jacek, et al. “Impact of BRCA Mutation Status on Tumor Dissemination
    Pattern, Surgical Outcome and Patient Survival in Primary and Recurrent High-Grade
    Serous Ovarian Cancer: A Multicenter Retrospective Study by the Ovarian Cancer
    Therapy-Innovative Models Prolong Survival (OCTIPS) Consortium.” <i>Annals of
    Surgical Oncology</i>, vol. 30, Springer Nature, 2023, pp. 35–45, doi:<a href="https://doi.org/10.1245/s10434-022-12459-3">10.1245/s10434-022-12459-3</a>.'
  short: J. Glajzer, D.C. Castillo-Tong, R. Richter, I. Vergote, H. Kulbe, A. Vanderstichele,
    I. Ruscito, F. Trillsch, A. Mustea, C. Kreuzinger, C. Gourley, H. Gabra, E.T.
    Taube, O. Dorigo, D. Horst, C. Keunecke, J. Baum, T. Angelotti, J. Sehouli, E.I.
    Braicu, Annals of Surgical Oncology 30 (2023) 35–45.
date_created: 2023-01-16T09:44:36Z
date_published: 2023-01-01T00:00:00Z
date_updated: 2023-09-05T15:18:37Z
day: '01'
ddc:
- '610'
department:
- _id: JoDa
doi: 10.1245/s10434-022-12459-3
external_id:
  isi:
  - '000852125500006'
file:
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  date_updated: 2023-02-02T13:01:20Z
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  file_size: 365865
  relation: main_file
  success: 1
file_date_updated: 2023-02-02T13:01:20Z
has_accepted_license: '1'
intvolume: '        30'
isi: 1
keyword:
- Oncology
- Surgery
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: 35-45
publication: Annals of Surgical Oncology
publication_identifier:
  eissn:
  - 1534-4681
  issn:
  - 1068-9265
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
  record:
  - id: '12115'
    relation: other
    status: public
scopus_import: '1'
status: public
title: 'Impact of BRCA mutation status on tumor dissemination pattern, surgical outcome
  and patient survival in primary and recurrent high-grade serous ovarian cancer:
  A multicenter retrospective study by the Ovarian Cancer Therapy-Innovative Models
  Prolong Survival (OCTIPS) consortium'
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  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 30
year: '2023'
...
---
_id: '12287'
abstract:
- lang: eng
  text: We present criteria for establishing a triangulation of a manifold. Given
    a manifold M, a simplicial complex A, and a map H from the underlying space of
    A to M, our criteria are presented in local coordinate charts for M, and ensure
    that H is a homeomorphism. These criteria do not require a differentiable structure,
    or even an explicit metric on M. No Delaunay property of A is assumed. The result
    provides a triangulation guarantee for algorithms that construct a simplicial
    complex by working in local coordinate patches. Because the criteria are easily
    verified in such a setting, they are expected to be of general use.
acknowledgement: "This work has been funded by the European Research Council under
  the European Union’s ERC Grant Agreement number 339025 GUDHI (Algorithmic Foundations
  of Geometric Understanding in Higher Dimensions). Arijit Ghosh is supported by Ramanujan
  Fellowship (No. SB/S2/RJN-064/2015). Part of this work was done when Arijit Ghosh
  was a Researcher at Max-Planck-Institute for Informatics, Germany, supported by
  the IndoGerman Max Planck Center for Computer Science (IMPECS). Mathijs Wintraecken
  also received funding from the European Union’s Horizon 2020 research and innovation
  programme under the Marie Skłodowska-Curie grant agreement No. 754411 and the Austrian
  Science Fund (FWF): M-3073. A part of the results described in this paper were presented
  at SoCG 2018 and in [3]. \r\nOpen access funding provided by the Austrian Science
  Fund (FWF)."
article_processing_charge: No
article_type: original
author:
- first_name: Jean-Daniel
  full_name: Boissonnat, Jean-Daniel
  last_name: Boissonnat
- first_name: Ramsay
  full_name: Dyer, Ramsay
  last_name: Dyer
- first_name: Arijit
  full_name: Ghosh, Arijit
  last_name: Ghosh
- first_name: Mathijs
  full_name: Wintraecken, Mathijs
  id: 307CFBC8-F248-11E8-B48F-1D18A9856A87
  last_name: Wintraecken
  orcid: 0000-0002-7472-2220
citation:
  ama: Boissonnat J-D, Dyer R, Ghosh A, Wintraecken M. Local criteria for triangulating
    general manifolds. <i>Discrete &#38; Computational Geometry</i>. 2023;69:156-191.
    doi:<a href="https://doi.org/10.1007/s00454-022-00431-7">10.1007/s00454-022-00431-7</a>
  apa: Boissonnat, J.-D., Dyer, R., Ghosh, A., &#38; Wintraecken, M. (2023). Local
    criteria for triangulating general manifolds. <i>Discrete &#38; Computational
    Geometry</i>. Springer Nature. <a href="https://doi.org/10.1007/s00454-022-00431-7">https://doi.org/10.1007/s00454-022-00431-7</a>
  chicago: Boissonnat, Jean-Daniel, Ramsay Dyer, Arijit Ghosh, and Mathijs Wintraecken.
    “Local Criteria for Triangulating General Manifolds.” <i>Discrete &#38; Computational
    Geometry</i>. Springer Nature, 2023. <a href="https://doi.org/10.1007/s00454-022-00431-7">https://doi.org/10.1007/s00454-022-00431-7</a>.
  ieee: J.-D. Boissonnat, R. Dyer, A. Ghosh, and M. Wintraecken, “Local criteria for
    triangulating general manifolds,” <i>Discrete &#38; Computational Geometry</i>,
    vol. 69. Springer Nature, pp. 156–191, 2023.
  ista: Boissonnat J-D, Dyer R, Ghosh A, Wintraecken M. 2023. Local criteria for triangulating
    general manifolds. Discrete &#38; Computational Geometry. 69, 156–191.
  mla: Boissonnat, Jean-Daniel, et al. “Local Criteria for Triangulating General Manifolds.”
    <i>Discrete &#38; Computational Geometry</i>, vol. 69, Springer Nature, 2023,
    pp. 156–91, doi:<a href="https://doi.org/10.1007/s00454-022-00431-7">10.1007/s00454-022-00431-7</a>.
  short: J.-D. Boissonnat, R. Dyer, A. Ghosh, M. Wintraecken, Discrete &#38; Computational
    Geometry 69 (2023) 156–191.
date_created: 2023-01-16T10:04:06Z
date_published: 2023-01-01T00:00:00Z
date_updated: 2023-08-01T12:47:32Z
day: '01'
ddc:
- '510'
department:
- _id: HeEd
doi: 10.1007/s00454-022-00431-7
ec_funded: 1
external_id:
  isi:
  - '000862193600001'
file:
- access_level: open_access
  checksum: 46352e0ee71e460848f88685ca852681
  content_type: application/pdf
  creator: dernst
  date_created: 2023-02-02T11:01:10Z
  date_updated: 2023-02-02T11:01:10Z
  file_id: '12488'
  file_name: 2023_DiscreteCompGeometry_Boissonnat.pdf
  file_size: 582850
  relation: main_file
  success: 1
file_date_updated: 2023-02-02T11:01:10Z
has_accepted_license: '1'
intvolume: '        69'
isi: 1
keyword:
- Computational Theory and Mathematics
- Discrete Mathematics and Combinatorics
- Geometry and Topology
- Theoretical Computer Science
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: 156-191
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '754411'
  name: ISTplus - Postdoctoral Fellowships
- _id: fc390959-9c52-11eb-aca3-afa58bd282b2
  grant_number: M03073
  name: Learning and triangulating manifolds via collapses
publication: Discrete & Computational Geometry
publication_identifier:
  eissn:
  - 1432-0444
  issn:
  - 0179-5376
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Local criteria for triangulating general manifolds
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 69
year: '2023'
...
---
_id: '12313'
abstract:
- lang: eng
  text: Let P be a nontorsion point on an elliptic curve defined over a number field
    K and consider the sequence {Bn}n∈N of the denominators of x(nP). We prove that
    every term of the sequence of the Bn has a primitive divisor for n greater than
    an effectively computable constant that we will explicitly compute. This constant
    will depend only on the model defining the curve.
acknowledgement: "This paper is part of the author’s PhD thesis at Università of Pisa.
  Moreover, this\r\nproject has received funding from the European Union’s Horizon
  2020 research\r\nand innovation programme under the Marie Skłodowska-Curie Grant
  Agreement\r\nNo. 101034413. I thank the referee for many helpful comments."
article_processing_charge: Yes (in subscription journal)
article_type: original
arxiv: 1
author:
- first_name: Matteo
  full_name: Verzobio, Matteo
  id: 7aa8f170-131e-11ed-88e1-a9efd01027cb
  last_name: Verzobio
  orcid: 0000-0002-0854-0306
citation:
  ama: Verzobio M. Some effectivity results for primitive divisors of elliptic divisibility 
    sequences. <i>Pacific Journal of Mathematics</i>. 2023;325(2):331-351. doi:<a
    href="https://doi.org/10.2140/pjm.2023.325.331">10.2140/pjm.2023.325.331</a>
  apa: Verzobio, M. (2023). Some effectivity results for primitive divisors of elliptic
    divisibility  sequences. <i>Pacific Journal of Mathematics</i>. Mathematical Sciences
    Publishers. <a href="https://doi.org/10.2140/pjm.2023.325.331">https://doi.org/10.2140/pjm.2023.325.331</a>
  chicago: Verzobio, Matteo. “Some Effectivity Results for Primitive Divisors of Elliptic
    Divisibility  Sequences.” <i>Pacific Journal of Mathematics</i>. Mathematical
    Sciences Publishers, 2023. <a href="https://doi.org/10.2140/pjm.2023.325.331">https://doi.org/10.2140/pjm.2023.325.331</a>.
  ieee: M. Verzobio, “Some effectivity results for primitive divisors of elliptic
    divisibility  sequences,” <i>Pacific Journal of Mathematics</i>, vol. 325, no.
    2. Mathematical Sciences Publishers, pp. 331–351, 2023.
  ista: Verzobio M. 2023. Some effectivity results for primitive divisors of elliptic
    divisibility  sequences. Pacific Journal of Mathematics. 325(2), 331–351.
  mla: Verzobio, Matteo. “Some Effectivity Results for Primitive Divisors of Elliptic
    Divisibility  Sequences.” <i>Pacific Journal of Mathematics</i>, vol. 325, no.
    2, Mathematical Sciences Publishers, 2023, pp. 331–51, doi:<a href="https://doi.org/10.2140/pjm.2023.325.331">10.2140/pjm.2023.325.331</a>.
  short: M. Verzobio, Pacific Journal of Mathematics 325 (2023) 331–351.
date_created: 2023-01-16T11:46:19Z
date_published: 2023-11-03T00:00:00Z
date_updated: 2023-12-13T11:18:14Z
day: '03'
ddc:
- '510'
department:
- _id: TiBr
doi: 10.2140/pjm.2023.325.331
ec_funded: 1
external_id:
  arxiv:
  - '2001.02987'
  isi:
  - '001104766900001'
file:
- access_level: open_access
  checksum: b6218d16a72742d8bb38d6fc3c9bb8c6
  content_type: application/pdf
  creator: dernst
  date_created: 2023-11-13T09:50:41Z
  date_updated: 2023-11-13T09:50:41Z
  file_id: '14525'
  file_name: 2023_PacificJourMaths_Verzobio.pdf
  file_size: 389897
  relation: main_file
  success: 1
file_date_updated: 2023-11-13T09:50:41Z
has_accepted_license: '1'
intvolume: '       325'
isi: 1
issue: '2'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
page: 331-351
project:
- _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c
  call_identifier: H2020
  grant_number: '101034413'
  name: 'IST-BRIDGE: International postdoctoral program'
publication: Pacific Journal of Mathematics
publication_identifier:
  eissn:
  - 0030-8730
publication_status: published
publisher: Mathematical Sciences Publishers
quality_controlled: '1'
scopus_import: '1'
status: public
title: Some effectivity results for primitive divisors of elliptic divisibility  sequences
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 325
year: '2023'
...
---
_id: '12329'
abstract:
- lang: eng
  text: In this article, we develop two independent and new approaches to model epidemic
    spread in a network. Contrary to the most studied models, those developed here
    allow for contacts with different probabilities of transmitting the disease (transmissibilities).
    We then examine each of these models using some mean field type approximations.
    The first model looks at the late-stage effects of an epidemic outbreak and allows
    for the computation of the probability that a given vertex was infected. This
    computation is based on a mean field approximation and only depends on the number
    of contacts and their transmissibilities. This approach shares many similarities
    with percolation models in networks. The second model we develop is a dynamic
    model which we analyze using a mean field approximation which highly reduces the
    dimensionality of the system. In particular, the original system which individually
    analyses each vertex of the network is reduced to one with as many equations as
    different transmissibilities. Perhaps the greatest contribution of this article
    is the observation that, in both these models, the existence and size of an epidemic
    outbreak are linked to the properties of a matrix which we call the R-matrix.
    This is a generalization of the basic reproduction number which more precisely
    characterizes the main routes of infection.
acknowledgement: Gonçalo Oliveira is supported by the NOMIS Foundation, Fundação Serrapilheira
  1812-27395, by CNPq grants 428959/2018-0 and 307475/2018-2, and by FAPERJ through
  the grant Jovem Cientista do Nosso Estado E-26/202.793/2019.
article_number: '468'
article_processing_charge: No
article_type: original
author:
- first_name: Arturo
  full_name: Gómez, Arturo
  last_name: Gómez
- first_name: Goncalo
  full_name: Oliveira, Goncalo
  id: 58abbde8-f455-11eb-a497-98c8fd71b905
  last_name: Oliveira
citation:
  ama: Gómez A, Oliveira G. New approaches to epidemic modeling on networks. <i>Scientific
    Reports</i>. 2023;13. doi:<a href="https://doi.org/10.1038/s41598-022-19827-9">10.1038/s41598-022-19827-9</a>
  apa: Gómez, A., &#38; Oliveira, G. (2023). New approaches to epidemic modeling on
    networks. <i>Scientific Reports</i>. Springer Nature. <a href="https://doi.org/10.1038/s41598-022-19827-9">https://doi.org/10.1038/s41598-022-19827-9</a>
  chicago: Gómez, Arturo, and Goncalo Oliveira. “New Approaches to Epidemic Modeling
    on Networks.” <i>Scientific Reports</i>. Springer Nature, 2023. <a href="https://doi.org/10.1038/s41598-022-19827-9">https://doi.org/10.1038/s41598-022-19827-9</a>.
  ieee: A. Gómez and G. Oliveira, “New approaches to epidemic modeling on networks,”
    <i>Scientific Reports</i>, vol. 13. Springer Nature, 2023.
  ista: Gómez A, Oliveira G. 2023. New approaches to epidemic modeling on networks.
    Scientific Reports. 13, 468.
  mla: Gómez, Arturo, and Goncalo Oliveira. “New Approaches to Epidemic Modeling on
    Networks.” <i>Scientific Reports</i>, vol. 13, 468, Springer Nature, 2023, doi:<a
    href="https://doi.org/10.1038/s41598-022-19827-9">10.1038/s41598-022-19827-9</a>.
  short: A. Gómez, G. Oliveira, Scientific Reports 13 (2023).
date_created: 2023-01-22T23:00:55Z
date_published: 2023-01-10T00:00:00Z
date_updated: 2023-08-01T12:31:40Z
day: '10'
ddc:
- '510'
department:
- _id: TaHa
doi: 10.1038/s41598-022-19827-9
external_id:
  isi:
  - '001003345000051'
file:
- access_level: open_access
  checksum: a8b83739f4a951e83e0b2a778f03b327
  content_type: application/pdf
  creator: dernst
  date_created: 2023-01-23T07:53:23Z
  date_updated: 2023-01-23T07:53:23Z
  file_id: '12336'
  file_name: 2023_ScientificReports_Gomez.pdf
  file_size: 2167792
  relation: main_file
  success: 1
file_date_updated: 2023-01-23T07:53:23Z
has_accepted_license: '1'
intvolume: '        13'
isi: 1
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
publication: Scientific Reports
publication_identifier:
  eissn:
  - 2045-2322
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: New approaches to epidemic modeling on networks
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 13
year: '2023'
...
---
_id: '12330'
abstract:
- lang: eng
  text: 'The design and implementation of efficient concurrent data structures has
    seen significant attention. However, most of this work has focused on concurrent
    data structures providing good worst-case guarantees, although, in real workloads,
    objects are often accessed at different rates. Efficient distribution-adaptive
    data structures, such as splay-trees, are known in the sequential case; however,
    they often are hard to translate efficiently to the concurrent case. We investigate
    distribution-adaptive concurrent data structures, and propose a new design called
    the splay-list. At a high level, the splay-list is similar to a standard skip-list,
    with the key distinction that the height of each element adapts dynamically to
    its access rate: popular elements “move up,” whereas rarely-accessed elements
    decrease in height. We show that the splay-list provides order-optimal amortized
    complexity bounds for a subset of operations, while being amenable to efficient
    concurrent implementation. Experiments show that the splay-list can leverage distribution-adaptivity
    for performance, and can outperform the only previously-known distribution-adaptive
    concurrent design in certain workloads.'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Vitalii
  full_name: Aksenov, Vitalii
  id: 2980135A-F248-11E8-B48F-1D18A9856A87
  last_name: Aksenov
- first_name: Dan-Adrian
  full_name: Alistarh, Dan-Adrian
  id: 4A899BFC-F248-11E8-B48F-1D18A9856A87
  last_name: Alistarh
  orcid: 0000-0003-3650-940X
- first_name: Alexandra
  full_name: Drozdova, Alexandra
  last_name: Drozdova
- first_name: Amirkeivan
  full_name: Mohtashami, Amirkeivan
  last_name: Mohtashami
citation:
  ama: 'Aksenov V, Alistarh D-A, Drozdova A, Mohtashami A. The splay-list: A distribution-adaptive
    concurrent skip-list. <i>Distributed Computing</i>. 2023;36:395-418. doi:<a href="https://doi.org/10.1007/s00446-022-00441-x">10.1007/s00446-022-00441-x</a>'
  apa: 'Aksenov, V., Alistarh, D.-A., Drozdova, A., &#38; Mohtashami, A. (2023). The
    splay-list: A distribution-adaptive concurrent skip-list. <i>Distributed Computing</i>.
    Springer Nature. <a href="https://doi.org/10.1007/s00446-022-00441-x">https://doi.org/10.1007/s00446-022-00441-x</a>'
  chicago: 'Aksenov, Vitalii, Dan-Adrian Alistarh, Alexandra Drozdova, and Amirkeivan
    Mohtashami. “The Splay-List: A Distribution-Adaptive Concurrent Skip-List.” <i>Distributed
    Computing</i>. Springer Nature, 2023. <a href="https://doi.org/10.1007/s00446-022-00441-x">https://doi.org/10.1007/s00446-022-00441-x</a>.'
  ieee: 'V. Aksenov, D.-A. Alistarh, A. Drozdova, and A. Mohtashami, “The splay-list:
    A distribution-adaptive concurrent skip-list,” <i>Distributed Computing</i>, vol.
    36. Springer Nature, pp. 395–418, 2023.'
  ista: 'Aksenov V, Alistarh D-A, Drozdova A, Mohtashami A. 2023. The splay-list:
    A distribution-adaptive concurrent skip-list. Distributed Computing. 36, 395–418.'
  mla: 'Aksenov, Vitalii, et al. “The Splay-List: A Distribution-Adaptive Concurrent
    Skip-List.” <i>Distributed Computing</i>, vol. 36, Springer Nature, 2023, pp.
    395–418, doi:<a href="https://doi.org/10.1007/s00446-022-00441-x">10.1007/s00446-022-00441-x</a>.'
  short: V. Aksenov, D.-A. Alistarh, A. Drozdova, A. Mohtashami, Distributed Computing
    36 (2023) 395–418.
date_created: 2023-01-22T23:00:55Z
date_published: 2023-09-01T00:00:00Z
date_updated: 2025-07-22T14:06:00Z
day: '01'
department:
- _id: DaAl
doi: 10.1007/s00446-022-00441-x
external_id:
  arxiv:
  - '2008.01009'
  isi:
  - '000913424000001'
  oaworkID:
  - w4390499170
intvolume: '        36'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2008.01009
month: '09'
oa: 1
oa_version: Preprint
oaworkID: 1
page: 395-418
publication: Distributed Computing
publication_identifier:
  eissn:
  - 1432-0452
  issn:
  - 0178-2770
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'The splay-list: A distribution-adaptive concurrent skip-list'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 36
year: '2023'
...
---
_id: '12331'
abstract:
- lang: eng
  text: High carrier mobility is critical to improving thermoelectric performance
    over a broad temperature range. However, traditional doping inevitably deteriorates
    carrier mobility. Herein, we develop a strategy for fine tuning of defects to
    improve carrier mobility. To begin, n-type PbTe is created by compensating for
    the intrinsic Pb vacancy in bare PbTe. Excess Pb2+ reduces vacancy scattering,
    resulting in a high carrier mobility of ∼3400 cm2 V–1 s–1. Then, excess Ag is
    introduced to compensate for the remaining intrinsic Pb vacancies. We find that
    excess Ag exhibits a dynamic doping process with increasing temperatures, increasing
    both the carrier concentration and carrier mobility throughout a wide temperature
    range; specifically, an ultrahigh carrier mobility ∼7300 cm2 V–1 s–1 is obtained
    for Pb1.01Te + 0.002Ag at 300 K. Moreover, the dynamic doping-induced high carrier
    concentration suppresses the bipolar thermal conductivity at high temperatures.
    The final step is using iodine to optimize the carrier concentration to ∼1019
    cm–3. Ultimately, a maximum ZT value of ∼1.5 and a large average ZTave value of
    ∼1.0 at 300–773 K are obtained for Pb1.01Te0.998I0.002 + 0.002Ag. These findings
    demonstrate that fine tuning of defects with <0.5% impurities can remarkably enhance
    carrier mobility and improve thermoelectric performance.
acknowledgement: The National Key Research and Development Program of China (2018YFA0702100),
  the Basic Science Center Project of the National Natural Science Foundation of China
  (51788104), the National Natural Science Foundation of China (51571007 and 51772012),
  the Beijing Natural Science Foundation (JQ18004), the 111 Project (B17002), the
  National Science Fund for Distinguished Young Scholars (51925101), and the FWF “Lise
  Meitner Fellowship” (grant agreement M2889-N). Open Access is funded by the Austrian
  Science Fund (FWF).
article_processing_charge: No
article_type: original
author:
- first_name: Siqi
  full_name: Wang, Siqi
  last_name: Wang
- first_name: Cheng
  full_name: Chang, Cheng
  id: 9E331C2E-9F27-11E9-AE48-5033E6697425
  last_name: Chang
  orcid: 0000-0002-9515-4277
- first_name: Shulin
  full_name: Bai, Shulin
  last_name: Bai
- first_name: Bingchao
  full_name: Qin, Bingchao
  last_name: Qin
- first_name: Yingcai
  full_name: Zhu, Yingcai
  last_name: Zhu
- first_name: Shaoping
  full_name: Zhan, Shaoping
  last_name: Zhan
- first_name: Junqing
  full_name: Zheng, Junqing
  last_name: Zheng
- first_name: Shuwei
  full_name: Tang, Shuwei
  last_name: Tang
- first_name: Li Dong
  full_name: Zhao, Li Dong
  last_name: Zhao
citation:
  ama: Wang S, Chang C, Bai S, et al. Fine tuning of defects enables high carrier
    mobility and enhanced thermoelectric performance of n-type PbTe. <i>Chemistry
    of Materials</i>. 2023;35(2):755-763. doi:<a href="https://doi.org/10.1021/acs.chemmater.2c03542">10.1021/acs.chemmater.2c03542</a>
  apa: Wang, S., Chang, C., Bai, S., Qin, B., Zhu, Y., Zhan, S., … Zhao, L. D. (2023).
    Fine tuning of defects enables high carrier mobility and enhanced thermoelectric
    performance of n-type PbTe. <i>Chemistry of Materials</i>. American Chemical Society.
    <a href="https://doi.org/10.1021/acs.chemmater.2c03542">https://doi.org/10.1021/acs.chemmater.2c03542</a>
  chicago: Wang, Siqi, Cheng Chang, Shulin Bai, Bingchao Qin, Yingcai Zhu, Shaoping
    Zhan, Junqing Zheng, Shuwei Tang, and Li Dong Zhao. “Fine Tuning of Defects Enables
    High Carrier Mobility and Enhanced Thermoelectric Performance of N-Type PbTe.”
    <i>Chemistry of Materials</i>. American Chemical Society, 2023. <a href="https://doi.org/10.1021/acs.chemmater.2c03542">https://doi.org/10.1021/acs.chemmater.2c03542</a>.
  ieee: S. Wang <i>et al.</i>, “Fine tuning of defects enables high carrier mobility
    and enhanced thermoelectric performance of n-type PbTe,” <i>Chemistry of Materials</i>,
    vol. 35, no. 2. American Chemical Society, pp. 755–763, 2023.
  ista: Wang S, Chang C, Bai S, Qin B, Zhu Y, Zhan S, Zheng J, Tang S, Zhao LD. 2023.
    Fine tuning of defects enables high carrier mobility and enhanced thermoelectric
    performance of n-type PbTe. Chemistry of Materials. 35(2), 755–763.
  mla: Wang, Siqi, et al. “Fine Tuning of Defects Enables High Carrier Mobility and
    Enhanced Thermoelectric Performance of N-Type PbTe.” <i>Chemistry of Materials</i>,
    vol. 35, no. 2, American Chemical Society, 2023, pp. 755–63, doi:<a href="https://doi.org/10.1021/acs.chemmater.2c03542">10.1021/acs.chemmater.2c03542</a>.
  short: S. Wang, C. Chang, S. Bai, B. Qin, Y. Zhu, S. Zhan, J. Zheng, S. Tang, L.D.
    Zhao, Chemistry of Materials 35 (2023) 755–763.
date_created: 2023-01-22T23:00:55Z
date_published: 2023-01-24T00:00:00Z
date_updated: 2023-08-14T12:57:44Z
day: '24'
ddc:
- '540'
department:
- _id: MaIb
doi: 10.1021/acs.chemmater.2c03542
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title: Fine tuning of defects enables high carrier mobility and enhanced thermoelectric
  performance of n-type PbTe
tmp:
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  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 35
year: '2023'
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abstract:
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  text: Regulation of the Arp2/3 complex is required for productive nucleation of
    branched actin networks. An emerging aspect of regulation is the incorporation
    of subunit isoforms into the Arp2/3 complex. Specifically, both ArpC5 subunit
    isoforms, ArpC5 and ArpC5L, have been reported to fine-tune nucleation activity
    and branch junction stability. We have combined reverse genetics and cellular
    structural biology to describe how ArpC5 and ArpC5L differentially affect cell
    migration. Both define the structural stability of ArpC1 in branch junctions and,
    in turn, by determining protrusion characteristics, affect protein dynamics and
    actin network ultrastructure. ArpC5 isoforms also affect the positioning of members
    of the Ena/Vasodilator-stimulated phosphoprotein (VASP) family of actin filament
    elongators, which mediate ArpC5 isoform–specific effects on the actin assembly
    level. Our results suggest that ArpC5 and Ena/VASP proteins are part of a signaling
    pathway enhancing cell migration.</jats:p>
acknowledged_ssus:
- _id: ScienComp
- _id: LifeSc
- _id: Bio
- _id: EM-Fac
acknowledgement: "We would like to thank K. von Peinen and B. Denker (Helmholtz Centre
  for Infection Research, Braunschweig, Germany) for experimental and technical assistance,
  respectively.\r\nThis research was supported by the Scientific Service Units (SSUs)
  of ISTA through resources provided by Scientific Computing (SciComp), the Life Science
  Facility (LSF), the Imaging and Optics facility (IOF), and the Electron Microscopy
  Facility (EMF). We acknowledge support from ISTA and from the Austrian Science Fund
  (FWF) (P33367) to F.K.M.S., from the Research Training Group GRK2223 and the Helmholtz
  Society to K.R,. and from the Deutsche Forschungsgemeinschaft (DFG) to J.F. and
  K.R."
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  id: 404F5528-F248-11E8-B48F-1D18A9856A87
  last_name: Fäßler
  orcid: 0000-0001-7149-769X
- first_name: Manjunath
  full_name: Javoor, Manjunath
  id: 305ab18b-dc7d-11ea-9b2f-b58195228ea2
  last_name: Javoor
- first_name: Julia
  full_name: Datler, Julia
  id: 3B12E2E6-F248-11E8-B48F-1D18A9856A87
  last_name: Datler
  orcid: 0000-0002-3616-8580
- first_name: Hermann
  full_name: Döring, Hermann
  last_name: Döring
- first_name: Florian
  full_name: Hofer, Florian
  id: b9d234ba-9e33-11ed-95b6-cd561df280e6
  last_name: Hofer
- first_name: Georgi A
  full_name: Dimchev, Georgi A
  id: 38C393BE-F248-11E8-B48F-1D18A9856A87
  last_name: Dimchev
  orcid: 0000-0001-8370-6161
- first_name: Victor-Valentin
  full_name: Hodirnau, Victor-Valentin
  id: 3661B498-F248-11E8-B48F-1D18A9856A87
  last_name: Hodirnau
- first_name: Jan
  full_name: Faix, Jan
  last_name: Faix
- first_name: Klemens
  full_name: Rottner, Klemens
  last_name: Rottner
- first_name: Florian KM
  full_name: Schur, Florian KM
  id: 48AD8942-F248-11E8-B48F-1D18A9856A87
  last_name: Schur
  orcid: 0000-0003-4790-8078
citation:
  ama: Fäßler F, Javoor M, Datler J, et al. ArpC5 isoforms regulate Arp2/3 complex–dependent
    protrusion through differential Ena/VASP positioning. <i>Science Advances</i>.
    2023;9(3). doi:<a href="https://doi.org/10.1126/sciadv.add6495">10.1126/sciadv.add6495</a>
  apa: Fäßler, F., Javoor, M., Datler, J., Döring, H., Hofer, F., Dimchev, G. A.,
    … Schur, F. K. (2023). ArpC5 isoforms regulate Arp2/3 complex–dependent protrusion
    through differential Ena/VASP positioning. <i>Science Advances</i>. American Association
    for the Advancement of Science. <a href="https://doi.org/10.1126/sciadv.add6495">https://doi.org/10.1126/sciadv.add6495</a>
  chicago: Fäßler, Florian, Manjunath Javoor, Julia Datler, Hermann Döring, Florian
    Hofer, Georgi A Dimchev, Victor-Valentin Hodirnau, Jan Faix, Klemens Rottner,
    and Florian KM Schur. “ArpC5 Isoforms Regulate Arp2/3 Complex–Dependent Protrusion
    through Differential Ena/VASP Positioning.” <i>Science Advances</i>. American
    Association for the Advancement of Science, 2023. <a href="https://doi.org/10.1126/sciadv.add6495">https://doi.org/10.1126/sciadv.add6495</a>.
  ieee: F. Fäßler <i>et al.</i>, “ArpC5 isoforms regulate Arp2/3 complex–dependent
    protrusion through differential Ena/VASP positioning,” <i>Science Advances</i>,
    vol. 9, no. 3. American Association for the Advancement of Science, 2023.
  ista: Fäßler F, Javoor M, Datler J, Döring H, Hofer F, Dimchev GA, Hodirnau V-V,
    Faix J, Rottner K, Schur FK. 2023. ArpC5 isoforms regulate Arp2/3 complex–dependent
    protrusion through differential Ena/VASP positioning. Science Advances. 9(3),
    add6495.
  mla: Fäßler, Florian, et al. “ArpC5 Isoforms Regulate Arp2/3 Complex–Dependent Protrusion
    through Differential Ena/VASP Positioning.” <i>Science Advances</i>, vol. 9, no.
    3, add6495, American Association for the Advancement of Science, 2023, doi:<a
    href="https://doi.org/10.1126/sciadv.add6495">10.1126/sciadv.add6495</a>.
  short: F. Fäßler, M. Javoor, J. Datler, H. Döring, F. Hofer, G.A. Dimchev, V.-V.
    Hodirnau, J. Faix, K. Rottner, F.K. Schur, Science Advances 9 (2023).
date_created: 2023-01-23T07:26:42Z
date_published: 2023-01-20T00:00:00Z
date_updated: 2023-11-21T08:05:35Z
day: '20'
ddc:
- '570'
department:
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- _id: EM-Fac
doi: 10.1126/sciadv.add6495
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title: ArpC5 isoforms regulate Arp2/3 complex–dependent protrusion through differential
  Ena/VASP positioning
tmp:
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type: journal_article
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...
---
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abstract:
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  text: Statistics of natural scenes are not uniform - their structure varies dramatically
    from ground to sky. It remains unknown whether these non-uniformities are reflected
    in the large-scale organization of the early visual system and what benefits such
    adaptations would confer. Here, by relying on the efficient coding hypothesis,
    we predict that changes in the structure of receptive fields across visual space
    increase the efficiency of sensory coding. We show experimentally that, in agreement
    with our predictions, receptive fields of retinal ganglion cells change their
    shape along the dorsoventral retinal axis, with a marked surround asymmetry at
    the visual horizon. Our work demonstrates that, according to principles of efficient
    coding, the panoramic structure of natural scenes is exploited by the retina across
    space and cell-types.
acknowledged_ssus:
- _id: ScienComp
- _id: PreCl
- _id: LifeSc
- _id: Bio
acknowledgement: We thank Hiroki Asari for sharing the dataset of naturalistic images,
  Anton Sumser for sharing visual stimulus code, Yoav Ben Simon for initial explorative
  work with the generation of AAVs, and Tomas Vega-Zuñiga for help with immunostainings.
  We also thank Gasper Tkacik and members of the Neuroethology group for their comments
  on the manuscript. This research was supported by the Scientific Service Units of
  IST Austria through resources provided by Scientific Computing, the Preclinical
  Facility, the Lab Support Facility, and the Imaging and Optics Facility. This work
  was supported by European Union Horizon 2020 Marie Skłodowska-Curie grant 665385
  (DG), Austrian Science Fund (FWF) stand-alone grant P 34015 (WM), Human Frontiers
  Science Program LT000256/2018-L (AS), EMBO ALTF 1098-2017 (AS) and the European
  Research Council Starting Grant 756502 (MJ).
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Divyansh
  full_name: Gupta, Divyansh
  id: 2A485EBE-F248-11E8-B48F-1D18A9856A87
  last_name: Gupta
  orcid: 0000-0001-7400-6665
- first_name: Wiktor F
  full_name: Mlynarski, Wiktor F
  id: 358A453A-F248-11E8-B48F-1D18A9856A87
  last_name: Mlynarski
- first_name: Anton L
  full_name: Sumser, Anton L
  id: 3320A096-F248-11E8-B48F-1D18A9856A87
  last_name: Sumser
  orcid: 0000-0002-4792-1881
- first_name: Olga
  full_name: Symonova, Olga
  id: 3C0C7BC6-F248-11E8-B48F-1D18A9856A87
  last_name: Symonova
  orcid: 0000-0003-2012-9947
- first_name: Jan
  full_name: Svaton, Jan
  id: f7f724c3-9d6f-11ed-9f44-e5c5f3a5bee2
  last_name: Svaton
  orcid: 0000-0002-6198-2939
- first_name: Maximilian A
  full_name: Jösch, Maximilian A
  id: 2BD278E6-F248-11E8-B48F-1D18A9856A87
  last_name: Jösch
  orcid: 0000-0002-3937-1330
citation:
  ama: Gupta D, Mlynarski WF, Sumser AL, Symonova O, Svaton J, Jösch MA. Panoramic
    visual statistics shape retina-wide organization of receptive fields. <i>Nature
    Neuroscience</i>. 2023;26:606-614. doi:<a href="https://doi.org/10.1038/s41593-023-01280-0">10.1038/s41593-023-01280-0</a>
  apa: Gupta, D., Mlynarski, W. F., Sumser, A. L., Symonova, O., Svaton, J., &#38;
    Jösch, M. A. (2023). Panoramic visual statistics shape retina-wide organization
    of receptive fields. <i>Nature Neuroscience</i>. Springer Nature. <a href="https://doi.org/10.1038/s41593-023-01280-0">https://doi.org/10.1038/s41593-023-01280-0</a>
  chicago: Gupta, Divyansh, Wiktor F Mlynarski, Anton L Sumser, Olga Symonova, Jan
    Svaton, and Maximilian A Jösch. “Panoramic Visual Statistics Shape Retina-Wide
    Organization of Receptive Fields.” <i>Nature Neuroscience</i>. Springer Nature,
    2023. <a href="https://doi.org/10.1038/s41593-023-01280-0">https://doi.org/10.1038/s41593-023-01280-0</a>.
  ieee: D. Gupta, W. F. Mlynarski, A. L. Sumser, O. Symonova, J. Svaton, and M. A.
    Jösch, “Panoramic visual statistics shape retina-wide organization of receptive
    fields,” <i>Nature Neuroscience</i>, vol. 26. Springer Nature, pp. 606–614, 2023.
  ista: Gupta D, Mlynarski WF, Sumser AL, Symonova O, Svaton J, Jösch MA. 2023. Panoramic
    visual statistics shape retina-wide organization of receptive fields. Nature Neuroscience.
    26, 606–614.
  mla: Gupta, Divyansh, et al. “Panoramic Visual Statistics Shape Retina-Wide Organization
    of Receptive Fields.” <i>Nature Neuroscience</i>, vol. 26, Springer Nature, 2023,
    pp. 606–14, doi:<a href="https://doi.org/10.1038/s41593-023-01280-0">10.1038/s41593-023-01280-0</a>.
  short: D. Gupta, W.F. Mlynarski, A.L. Sumser, O. Symonova, J. Svaton, M.A. Jösch,
    Nature Neuroscience 26 (2023) 606–614.
date_created: 2023-01-23T14:14:19Z
date_published: 2023-04-01T00:00:00Z
date_updated: 2023-10-04T11:41:05Z
day: '01'
ddc:
- '570'
department:
- _id: GradSch
- _id: MaJö
doi: 10.1038/s41593-023-01280-0
ec_funded: 1
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  grant_number: '665385'
  name: International IST Doctoral Program
- _id: 626c45b5-2b32-11ec-9570-e509828c1ba6
  grant_number: P34015
  name: Efficient coding with biophysical realism
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  call_identifier: H2020
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  name: Circuits of Visual Attention
- _id: 266D407A-B435-11E9-9278-68D0E5697425
  grant_number: LT000256
  name: Neuronal networks of salience and spatial detection in the murine superior
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abstract:
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  text: 'Statistics of natural scenes are not uniform - their structure varies dramatically
    from ground to sky. It remains unknown whether these non-uniformities are reflected
    in the large-scale organization of the early visual system and what benefits such
    adaptations would confer. Here, by relying on the efficient coding hypothesis,
    we predict that changes in the structure of receptive fields across visual space
    increase the efficiency of sensory coding. We show experimentally that, in agreement
    with our predictions, receptive fields of retinal ganglion cells change their
    shape along the dorsoventral retinal axis, with a marked surround asymmetry at
    the visual horizon. Our work demonstrates that, according to principles of efficient
    coding, the panoramic structure of natural scenes is exploited by the retina across
    space and cell-types. '
acknowledged_ssus:
- _id: ScienComp
- _id: M-Shop
- _id: Bio
- _id: PreCl
- _id: LifeSc
article_processing_charge: No
author:
- first_name: Divyansh
  full_name: Gupta, Divyansh
  id: 2A485EBE-F248-11E8-B48F-1D18A9856A87
  last_name: Gupta
  orcid: 0000-0001-7400-6665
- first_name: Anton L
  full_name: Sumser, Anton L
  id: 3320A096-F248-11E8-B48F-1D18A9856A87
  last_name: Sumser
  orcid: 0000-0002-4792-1881
- first_name: Maximilian A
  full_name: Jösch, Maximilian A
  id: 2BD278E6-F248-11E8-B48F-1D18A9856A87
  last_name: Jösch
  orcid: 0000-0002-3937-1330
citation:
  ama: 'Gupta D, Sumser AL, Jösch MA. Research Data for: Panoramic visual statistics
    shape retina-wide organization of receptive fields. 2023. doi:<a href="https://doi.org/10.15479/AT:ISTA:12370">10.15479/AT:ISTA:12370</a>'
  apa: 'Gupta, D., Sumser, A. L., &#38; Jösch, M. A. (2023). Research Data for: Panoramic
    visual statistics shape retina-wide organization of receptive fields. Institute
    of Science and Technology Austria. <a href="https://doi.org/10.15479/AT:ISTA:12370">https://doi.org/10.15479/AT:ISTA:12370</a>'
  chicago: 'Gupta, Divyansh, Anton L Sumser, and Maximilian A Jösch. “Research Data
    for: Panoramic Visual Statistics Shape Retina-Wide Organization of Receptive Fields.”
    Institute of Science and Technology Austria, 2023. <a href="https://doi.org/10.15479/AT:ISTA:12370">https://doi.org/10.15479/AT:ISTA:12370</a>.'
  ieee: 'D. Gupta, A. L. Sumser, and M. A. Jösch, “Research Data for: Panoramic visual
    statistics shape retina-wide organization of receptive fields.” Institute of Science
    and Technology Austria, 2023.'
  ista: 'Gupta D, Sumser AL, Jösch MA. 2023. Research Data for: Panoramic visual statistics
    shape retina-wide organization of receptive fields, Institute of Science and Technology
    Austria, <a href="https://doi.org/10.15479/AT:ISTA:12370">10.15479/AT:ISTA:12370</a>.'
  mla: 'Gupta, Divyansh, et al. <i>Research Data for: Panoramic Visual Statistics
    Shape Retina-Wide Organization of Receptive Fields</i>. Institute of Science and
    Technology Austria, 2023, doi:<a href="https://doi.org/10.15479/AT:ISTA:12370">10.15479/AT:ISTA:12370</a>.'
  short: D. Gupta, A.L. Sumser, M.A. Jösch, (2023).
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  id: 3C0C7BC6-F248-11E8-B48F-1D18A9856A87
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  id: f7f724c3-9d6f-11ed-9f44-e5c5f3a5bee2
  last_name: Svaton
date_created: 2023-01-25T12:45:18Z
date_published: 2023-01-26T00:00:00Z
date_updated: 2023-10-04T11:41:04Z
day: '26'
ddc:
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department:
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- _id: MaJö
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project:
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  call_identifier: H2020
  grant_number: '665385'
  name: International IST Doctoral Program
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publisher: Institute of Science and Technology Austria
related_material:
  record:
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    relation: used_in_publication
    status: public
status: public
title: 'Research Data for: Panoramic visual statistics shape retina-wide organization
  of receptive fields'
tmp:
  image: /images/cc_by_nc_sa.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC
    BY-NC-SA 4.0)
  short: CC BY-NC-SA (4.0)
type: research_data
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2023'
...
---
_id: '12407'
abstract:
- lang: eng
  text: "As the complexity and criticality of software increase every year, so does
    the importance of run-time monitoring. Third-party monitoring, with limited knowledge
    of the monitored software, and best-effort monitoring, which keeps pace with the
    monitored software, are especially valuable, yet underexplored areas of run-time
    monitoring. Most existing monitoring frameworks do not support their combination
    because they either require access to the monitored code for instrumentation purposes
    or the processing of all observed events, or both.\r\n\r\nWe present a middleware
    framework, VAMOS, for the run-time monitoring of software which is explicitly
    designed to support third-party and best-effort scenarios. The design goals of
    VAMOS are (i) efficiency (keeping pace at low overhead), (ii) flexibility (the
    ability to monitor black-box code through a variety of different event channels,
    and the connectability to monitors written in different specification languages),
    and (iii) ease-of-use. To achieve its goals, VAMOS combines aspects of event broker
    and event recognition systems with aspects of stream processing systems.\r\n\r\nWe
    implemented a prototype toolchain for VAMOS and conducted experiments including
    a case study of monitoring for data races. The results indicate that VAMOS enables
    writing useful yet efficient monitors, is compatible with a variety of event sources
    and monitor specifications, and simplifies key aspects of setting up a monitoring
    system from scratch."
acknowledgement: "This work was supported in part by the ERC-2020-AdG 101020093. \r\nThe
  authors would like to thank the anonymous FASE reviewers for their valuable feedback
  and suggestions."
alternative_title:
- IST Austria Technical Report
article_processing_charge: No
author:
- first_name: Marek
  full_name: Chalupa, Marek
  id: 87e34708-d6c6-11ec-9f5b-9391e7be2463
  last_name: Chalupa
- first_name: Fabian
  full_name: Mühlböck, Fabian
  id: 6395C5F6-89DF-11E9-9C97-6BDFE5697425
  last_name: Mühlböck
  orcid: 0000-0003-1548-0177
- first_name: Stefanie
  full_name: Muroya Lei, Stefanie
  id: a376de31-8972-11ed-ae7b-d0251c13c8ff
  last_name: Muroya Lei
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000-0002-2985-7724
citation:
  ama: 'Chalupa M, Mühlböck F, Muroya Lei S, Henzinger TA. <i>VAMOS: Middleware for
    Best-Effort Third-Party Monitoring</i>. Institute of Science and Technology Austria;
    2023. doi:<a href="https://doi.org/10.15479/AT:ISTA:12407">10.15479/AT:ISTA:12407</a>'
  apa: 'Chalupa, M., Mühlböck, F., Muroya Lei, S., &#38; Henzinger, T. A. (2023).
    <i>VAMOS: Middleware for Best-Effort Third-Party Monitoring</i>. Institute of
    Science and Technology Austria. <a href="https://doi.org/10.15479/AT:ISTA:12407">https://doi.org/10.15479/AT:ISTA:12407</a>'
  chicago: 'Chalupa, Marek, Fabian Mühlböck, Stefanie Muroya Lei, and Thomas A Henzinger.
    <i>VAMOS: Middleware for Best-Effort Third-Party Monitoring</i>. Institute of
    Science and Technology Austria, 2023. <a href="https://doi.org/10.15479/AT:ISTA:12407">https://doi.org/10.15479/AT:ISTA:12407</a>.'
  ieee: 'M. Chalupa, F. Mühlböck, S. Muroya Lei, and T. A. Henzinger, <i>VAMOS: Middleware
    for Best-Effort Third-Party Monitoring</i>. Institute of Science and Technology
    Austria, 2023.'
  ista: 'Chalupa M, Mühlböck F, Muroya Lei S, Henzinger TA. 2023. VAMOS: Middleware
    for Best-Effort Third-Party Monitoring, Institute of Science and Technology Austria,
    38p.'
  mla: 'Chalupa, Marek, et al. <i>VAMOS: Middleware for Best-Effort Third-Party Monitoring</i>.
    Institute of Science and Technology Austria, 2023, doi:<a href="https://doi.org/10.15479/AT:ISTA:12407">10.15479/AT:ISTA:12407</a>.'
  short: 'M. Chalupa, F. Mühlböck, S. Muroya Lei, T.A. Henzinger, VAMOS: Middleware
    for Best-Effort Third-Party Monitoring, Institute of Science and Technology Austria,
    2023.'
date_created: 2023-01-27T03:18:08Z
date_published: 2023-01-27T00:00:00Z
date_updated: 2023-04-25T07:19:06Z
day: '27'
ddc:
- '005'
department:
- _id: ToHe
doi: 10.15479/AT:ISTA:12407
ec_funded: 1
file:
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  date_updated: 2023-01-27T03:18:34Z
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  file_size: 662409
  relation: main_file
  success: 1
file_date_updated: 2023-01-27T03:18:34Z
has_accepted_license: '1'
keyword:
- runtime monitoring
- best effort
- third party
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: '38'
project:
- _id: 62781420-2b32-11ec-9570-8d9b63373d4d
  call_identifier: H2020
  grant_number: '101020093'
  name: Vigilant Algorithmic Monitoring of Software
publication_identifier:
  eissn:
  - 2664-1690
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
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    relation: later_version
    status: public
status: public
title: 'VAMOS: Middleware for Best-Effort Third-Party Monitoring'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2023'
...
---
_id: '12421'
abstract:
- lang: eng
  text: The actin cytoskeleton plays a key role in cell migration and cellular morphodynamics
    in most eukaryotes. The ability of the actin cytoskeleton to assemble and disassemble
    in a spatiotemporally controlled manner allows it to form higher-order structures,
    which can generate forces required for a cell to explore and navigate through
    its environment. It is regulated not only via a complex synergistic and competitive
    interplay between actin-binding proteins (ABP), but also by filament biochemistry
    and filament geometry. The lack of structural insights into how geometry and ABPs
    regulate the actin cytoskeleton limits our understanding of the molecular mechanisms
    that define actin cytoskeleton remodeling and, in turn, impact emerging cell migration
    characteristics. With the advent of cryo-electron microscopy (cryo-EM) and advanced
    computational methods, it is now possible to define these molecular mechanisms
    involving actin and its interactors at both atomic and ultra-structural levels
    in vitro and in cellulo. In this review, we will provide an overview of the available
    cryo-EM methods, applicable to further our understanding of the actin cytoskeleton,
    specifically in the context of cell migration. We will discuss how these methods
    have been employed to elucidate ABP- and geometry-defined regulatory mechanisms
    in initiating, maintaining, and disassembling cellular actin networks in migratory
    protrusions.
acknowledgement: 'We apologize for not being able to mention and cite additional excellent
  work that would have fit the scope of this review, due to space restraints. We thank
  Jesse Hansen for comments on the manuscript. We acknowledge support from the Austrian
  Science Fund (FWF): P33367 and the Institute of Science and Technology Austria.'
article_processing_charge: No
article_type: original
author:
- first_name: Florian
  full_name: Fäßler, Florian
  id: 404F5528-F248-11E8-B48F-1D18A9856A87
  last_name: Fäßler
  orcid: 0000-0001-7149-769X
- first_name: Manjunath
  full_name: Javoor, Manjunath
  id: 305ab18b-dc7d-11ea-9b2f-b58195228ea2
  last_name: Javoor
- first_name: Florian KM
  full_name: Schur, Florian KM
  id: 48AD8942-F248-11E8-B48F-1D18A9856A87
  last_name: Schur
  orcid: 0000-0003-4790-8078
citation:
  ama: Fäßler F, Javoor M, Schur FK. Deciphering the molecular mechanisms of actin
    cytoskeleton regulation in cell migration using cryo-EM. <i>Biochemical Society
    Transactions</i>. 2023;51(1):87-99. doi:<a href="https://doi.org/10.1042/bst20220221">10.1042/bst20220221</a>
  apa: Fäßler, F., Javoor, M., &#38; Schur, F. K. (2023). Deciphering the molecular
    mechanisms of actin cytoskeleton regulation in cell migration using cryo-EM. <i>Biochemical
    Society Transactions</i>. Portland Press. <a href="https://doi.org/10.1042/bst20220221">https://doi.org/10.1042/bst20220221</a>
  chicago: Fäßler, Florian, Manjunath Javoor, and Florian KM Schur. “Deciphering the
    Molecular Mechanisms of Actin Cytoskeleton Regulation in Cell Migration Using
    Cryo-EM.” <i>Biochemical Society Transactions</i>. Portland Press, 2023. <a href="https://doi.org/10.1042/bst20220221">https://doi.org/10.1042/bst20220221</a>.
  ieee: F. Fäßler, M. Javoor, and F. K. Schur, “Deciphering the molecular mechanisms
    of actin cytoskeleton regulation in cell migration using cryo-EM,” <i>Biochemical
    Society Transactions</i>, vol. 51, no. 1. Portland Press, pp. 87–99, 2023.
  ista: Fäßler F, Javoor M, Schur FK. 2023. Deciphering the molecular mechanisms of
    actin cytoskeleton regulation in cell migration using cryo-EM. Biochemical Society
    Transactions. 51(1), 87–99.
  mla: Fäßler, Florian, et al. “Deciphering the Molecular Mechanisms of Actin Cytoskeleton
    Regulation in Cell Migration Using Cryo-EM.” <i>Biochemical Society Transactions</i>,
    vol. 51, no. 1, Portland Press, 2023, pp. 87–99, doi:<a href="https://doi.org/10.1042/bst20220221">10.1042/bst20220221</a>.
  short: F. Fäßler, M. Javoor, F.K. Schur, Biochemical Society Transactions 51 (2023)
    87–99.
date_created: 2023-01-27T10:08:19Z
date_published: 2023-02-01T00:00:00Z
date_updated: 2023-08-01T12:55:32Z
day: '01'
ddc:
- '570'
department:
- _id: FlSc
doi: 10.1042/bst20220221
external_id:
  isi:
  - '000926043100001'
file:
- access_level: open_access
  checksum: 4e7069845e3dad22bb44fb71ec624c60
  content_type: application/pdf
  creator: dernst
  date_created: 2023-03-16T07:58:16Z
  date_updated: 2023-03-16T07:58:16Z
  file_id: '12728'
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  file_size: 10045006
  relation: main_file
  success: 1
file_date_updated: 2023-03-16T07:58:16Z
has_accepted_license: '1'
intvolume: '        51'
isi: 1
issue: '1'
keyword:
- Biochemistry
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
page: 87-99
project:
- _id: 9B954C5C-BA93-11EA-9121-9846C619BF3A
  grant_number: P33367
  name: Structure and isoform diversity of the Arp2/3 complex
publication: Biochemical Society Transactions
publication_identifier:
  eissn:
  - 1470-8752
  issn:
  - 0300-5127
publication_status: published
publisher: Portland Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Deciphering the molecular mechanisms of actin cytoskeleton regulation in cell
  migration using cryo-EM
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 51
year: '2023'
...
---
_id: '12427'
abstract:
- lang: eng
  text: 'Let k be a number field and X a smooth, geometrically integral quasi-projective
    variety over k. For any linear algebraic group G over k and any G-torsor g : Z
    → X, we observe that if the étale-Brauer obstruction is the only one for strong
    approximation off a finite set of places S for all twists of Z by elements in
    H^1(k, G), then the étale-Brauer obstruction is the only one for strong approximation
    off a finite set of places S for X. As an application, we show that any homogeneous
    space of the form G/H with G a connected linear algebraic group over k satisfies
    strong approximation off the infinite places with étale-Brauer obstruction, under
    some compactness assumptions when k is totally real. We also prove more refined
    strong approximation results for homogeneous spaces of the form G/H with G semisimple
    simply connected and H finite, using the theory of torsors and descent.'
article_processing_charge: No
article_type: original
author:
- first_name: Francesca
  full_name: Balestrieri, Francesca
  id: 3ACCD756-F248-11E8-B48F-1D18A9856A87
  last_name: Balestrieri
citation:
  ama: Balestrieri F. Some remarks on strong approximation and applications to homogeneous
    spaces of linear algebraic groups. <i>Proceedings of the American Mathematical
    Society</i>. 2023;151(3):907-914. doi:<a href="https://doi.org/10.1090/proc/15239">10.1090/proc/15239</a>
  apa: Balestrieri, F. (2023). Some remarks on strong approximation and applications
    to homogeneous spaces of linear algebraic groups. <i>Proceedings of the American
    Mathematical Society</i>. American Mathematical Society. <a href="https://doi.org/10.1090/proc/15239">https://doi.org/10.1090/proc/15239</a>
  chicago: Balestrieri, Francesca. “Some Remarks on Strong Approximation and Applications
    to Homogeneous Spaces of Linear Algebraic Groups.” <i>Proceedings of the American
    Mathematical Society</i>. American Mathematical Society, 2023. <a href="https://doi.org/10.1090/proc/15239">https://doi.org/10.1090/proc/15239</a>.
  ieee: F. Balestrieri, “Some remarks on strong approximation and applications to
    homogeneous spaces of linear algebraic groups,” <i>Proceedings of the American
    Mathematical Society</i>, vol. 151, no. 3. American Mathematical Society, pp.
    907–914, 2023.
  ista: Balestrieri F. 2023. Some remarks on strong approximation and applications
    to homogeneous spaces of linear algebraic groups. Proceedings of the American
    Mathematical Society. 151(3), 907–914.
  mla: Balestrieri, Francesca. “Some Remarks on Strong Approximation and Applications
    to Homogeneous Spaces of Linear Algebraic Groups.” <i>Proceedings of the American
    Mathematical Society</i>, vol. 151, no. 3, American Mathematical Society, 2023,
    pp. 907–14, doi:<a href="https://doi.org/10.1090/proc/15239">10.1090/proc/15239</a>.
  short: F. Balestrieri, Proceedings of the American Mathematical Society 151 (2023)
    907–914.
date_created: 2023-01-29T23:00:58Z
date_published: 2023-01-01T00:00:00Z
date_updated: 2023-08-01T13:03:32Z
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doi: 10.1090/proc/15239
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title: Some remarks on strong approximation and applications to homogeneous spaces
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type: journal_article
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year: '2023'
...
