---
_id: '5402'
abstract:
- lang: eng
text: "Linearizability requires that the outcome of calls by competing threads to
a concurrent data structure is the same as some sequential execution where each
thread has exclusive access to the data structure. In an ordered data structure,
such as a queue or a stack, linearizability is ensured by requiring threads commit
in the order dictated by the sequential semantics of the data structure; e.g.,
in a concurrent queue implementation a dequeue can only remove the oldest element.
\r\nIn this paper, we investigate the impact of this strict ordering, by comparing
what linearizability allows to what existing implementations do. We first give
an operational definition for linearizability which allows us to build the most
general linearizable implementation as a transition system for any given sequential
specification. We then use this operational definition to categorize linearizable
implementations based on whether they are bound or free. In a bound implementation,
whenever all threads observe the same logical state, the updates to the logical
state and the temporal order of commits coincide. All existing queue implementations
we know of are bound. We then proceed to present, to the best of our knowledge,
the first ever free queue implementation. Our experiments show that free implementations
have the potential for better performance by suffering less from contention."
alternative_title:
- IST Austria Technical Report
author:
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Ali
full_name: Sezgin, Ali
id: 4C7638DA-F248-11E8-B48F-1D18A9856A87
last_name: Sezgin
citation:
ama: Henzinger TA, Sezgin A. How Free Is Your Linearizable Concurrent Data Structure?
IST Austria; 2013. doi:10.15479/AT:IST-2013-123-v1-1
apa: Henzinger, T. A., & Sezgin, A. (2013). How free is your linearizable
concurrent data structure? IST Austria. https://doi.org/10.15479/AT:IST-2013-123-v1-1
chicago: Henzinger, Thomas A, and Ali Sezgin. How Free Is Your Linearizable Concurrent
Data Structure? IST Austria, 2013. https://doi.org/10.15479/AT:IST-2013-123-v1-1.
ieee: T. A. Henzinger and A. Sezgin, How free is your linearizable concurrent
data structure? IST Austria, 2013.
ista: Henzinger TA, Sezgin A. 2013. How free is your linearizable concurrent data
structure?, IST Austria, 16p.
mla: Henzinger, Thomas A., and Ali Sezgin. How Free Is Your Linearizable Concurrent
Data Structure? IST Austria, 2013, doi:10.15479/AT:IST-2013-123-v1-1.
short: T.A. Henzinger, A. Sezgin, How Free Is Your Linearizable Concurrent Data
Structure?, IST Austria, 2013.
date_created: 2018-12-12T11:39:07Z
date_published: 2013-06-12T00:00:00Z
date_updated: 2020-07-14T23:04:47Z
day: '12'
ddc:
- '000'
- '004'
department:
- _id: ToHe
doi: 10.15479/AT:IST-2013-123-v1-1
file:
- access_level: open_access
checksum: ce580605ae9756a8c99d7b403ebb8eed
content_type: application/pdf
creator: system
date_created: 2018-12-12T11:53:19Z
date_updated: 2020-07-14T12:46:45Z
file_id: '5480'
file_name: IST-2013-123-v1+1_main-concur2013.pdf
file_size: 249790
relation: main_file
file_date_updated: 2020-07-14T12:46:45Z
has_accepted_license: '1'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
page: '16'
publication_identifier:
issn:
- 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '123'
status: public
title: How free is your linearizable concurrent data structure?
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2013'
...
---
_id: '5403'
abstract:
- lang: eng
text: 'We consider concurrent games played by two-players on a finite state graph,
where in every round the players simultaneously choose a move, and the current
state along with the joint moves determine the successor state. We study the most
fundamental objective for concurrent games, namely, mean-payoff or limit-average
objective, where a reward is associated to every transition, and the goal of player
1 is to maximize the long-run average of the rewards, and the objective of player
2 is strictly the opposite (i.e., the games are zero-sum). The path constraint
for player 1 could be qualitative, i.e., the mean-payoff is the maximal reward,
or arbitrarily close to it; or quantitative, i.e., a given threshold between the
minimal and maximal reward. We consider the computation of the almost-sure (resp.
positive) winning sets, where player 1 can ensure that the path constraint is
satisfied with probability 1 (resp. positive probability). Almost-sure winning
with qualitative constraint exactly corresponds to the question whether there
exists a strategy to ensure that the payoff is the maximal reward of the game.
Our main results for qualitative path constraints are as follows: (1) we establish
qualitative determinacy results that show for every state either player 1 has
a strategy to ensure almost-sure (resp. positive) winning against all player-2
strategies or player 2 has a spoiling strategy to falsify almost-sure (resp. positive)
winning against all player-1 strategies; (2) we present optimal strategy complexity
results that precisely characterize the classes of strategies required for almost-sure
and positive winning for both players; and (3) we present quadratic time algorithms
to compute the almost-sure and the positive winning sets, matching the best known
bound of the algorithms for much simpler problems (such as reachability objectives).
For quantitative constraints we show that a polynomial time solution for the almost-sure
or the positive winning set would imply a solution to a long-standing open problem
(of solving the value problem of mean-payoff games) that is not known to be in
polynomial time.'
alternative_title:
- IST Austria Technical Report
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Rasmus
full_name: Ibsen-Jensen, Rasmus
id: 3B699956-F248-11E8-B48F-1D18A9856A87
last_name: Ibsen-Jensen
orcid: 0000-0003-4783-0389
citation:
ama: Chatterjee K, Ibsen-Jensen R. Qualitative Analysis of Concurrent Mean-Payoff
Games. IST Austria; 2013. doi:10.15479/AT:IST-2013-126-v1-1
apa: Chatterjee, K., & Ibsen-Jensen, R. (2013). Qualitative analysis of concurrent
mean-payoff games. IST Austria. https://doi.org/10.15479/AT:IST-2013-126-v1-1
chicago: Chatterjee, Krishnendu, and Rasmus Ibsen-Jensen. Qualitative Analysis
of Concurrent Mean-Payoff Games. IST Austria, 2013. https://doi.org/10.15479/AT:IST-2013-126-v1-1.
ieee: K. Chatterjee and R. Ibsen-Jensen, Qualitative analysis of concurrent mean-payoff
games. IST Austria, 2013.
ista: Chatterjee K, Ibsen-Jensen R. 2013. Qualitative analysis of concurrent mean-payoff
games, IST Austria, 33p.
mla: Chatterjee, Krishnendu, and Rasmus Ibsen-Jensen. Qualitative Analysis of
Concurrent Mean-Payoff Games. IST Austria, 2013, doi:10.15479/AT:IST-2013-126-v1-1.
short: K. Chatterjee, R. Ibsen-Jensen, Qualitative Analysis of Concurrent Mean-Payoff
Games, IST Austria, 2013.
date_created: 2018-12-12T11:39:08Z
date_published: 2013-07-03T00:00:00Z
date_updated: 2023-02-23T12:22:53Z
day: '03'
ddc:
- '000'
- '005'
department:
- _id: KrCh
doi: 10.15479/AT:IST-2013-126-v1-1
file:
- access_level: open_access
checksum: 063868c665beec37bf28160e2a695746
content_type: application/pdf
creator: system
date_created: 2018-12-12T11:53:49Z
date_updated: 2020-07-14T12:46:45Z
file_id: '5510'
file_name: IST-2013-126-v1+1_soda_full.pdf
file_size: 434523
relation: main_file
file_date_updated: 2020-07-14T12:46:45Z
has_accepted_license: '1'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: '33'
publication_identifier:
issn:
- 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '126'
related_material:
record:
- id: '524'
relation: later_version
status: public
status: public
title: Qualitative analysis of concurrent mean-payoff games
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2013'
...
---
_id: '5404'
abstract:
- lang: eng
text: 'We study finite-state two-player (zero-sum) concurrent mean-payoff games
played on a graph. We focus on the important sub-class of ergodic games where
all states are visited infinitely often with probability 1. The algorithmic study
of ergodic games was initiated in a seminal work of Hoffman and Karp in 1966,
but all basic complexity questions have remained unresolved. Our main results
for ergodic games are as follows: We establish (1) an optimal exponential bound
on the patience of stationary strategies (where patience of a distribution is
the inverse of the smallest positive probability and represents a complexity measure
of a stationary strategy); (2) the approximation problem lie in FNP; (3) the approximation
problem is at least as hard as the decision problem for simple stochastic games
(for which NP and coNP is the long-standing best known bound). We show that the
exact value can be expressed in the existential theory of the reals, and also
establish square-root sum hardness for a related class of games.'
alternative_title:
- IST Austria Technical Report
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Rasmus
full_name: Ibsen-Jensen, Rasmus
id: 3B699956-F248-11E8-B48F-1D18A9856A87
last_name: Ibsen-Jensen
orcid: 0000-0003-4783-0389
citation:
ama: Chatterjee K, Ibsen-Jensen R. The Complexity of Ergodic Games. IST Austria;
2013. doi:10.15479/AT:IST-2013-127-v1-1
apa: Chatterjee, K., & Ibsen-Jensen, R. (2013). The complexity of ergodic
games. IST Austria. https://doi.org/10.15479/AT:IST-2013-127-v1-1
chicago: Chatterjee, Krishnendu, and Rasmus Ibsen-Jensen. The Complexity of Ergodic
Games. IST Austria, 2013. https://doi.org/10.15479/AT:IST-2013-127-v1-1.
ieee: K. Chatterjee and R. Ibsen-Jensen, The complexity of ergodic games.
IST Austria, 2013.
ista: Chatterjee K, Ibsen-Jensen R. 2013. The complexity of ergodic games, IST Austria,
29p.
mla: Chatterjee, Krishnendu, and Rasmus Ibsen-Jensen. The Complexity of Ergodic
Games. IST Austria, 2013, doi:10.15479/AT:IST-2013-127-v1-1.
short: K. Chatterjee, R. Ibsen-Jensen, The Complexity of Ergodic Games, IST Austria,
2013.
date_created: 2018-12-12T11:39:08Z
date_published: 2013-07-03T00:00:00Z
date_updated: 2023-02-23T10:30:55Z
day: '03'
ddc:
- '000'
- '005'
department:
- _id: KrCh
doi: 10.15479/AT:IST-2013-127-v1-1
file:
- access_level: open_access
checksum: 79ee5e677a82611ce06e0360c69d494a
content_type: application/pdf
creator: system
date_created: 2018-12-12T11:53:35Z
date_updated: 2020-07-14T12:46:45Z
file_id: '5496'
file_name: IST-2013-127-v1+1_ergodic.pdf
file_size: 517275
relation: main_file
file_date_updated: 2020-07-14T12:46:45Z
has_accepted_license: '1'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: '29'
publication_identifier:
issn:
- 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '127'
related_material:
record:
- id: '2162'
relation: later_version
status: public
status: public
title: The complexity of ergodic games
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2013'
...
---
_id: '5405'
abstract:
- lang: eng
text: "The theory of graph games is the foundation for modeling and synthesizing
reactive processes. In the synthesis of stochastic processes, we use 2-1/2-player
games where some transitions of the game graph are controlled by two adversarial
players, the System and the Environment, and the other transitions are determined
probabilistically. We consider 2-1/2-player games where the objective of the System
is the conjunction of a qualitative objective (specified as a parity condition)
and a quantitative objective (specified as a mean-payoff condition). We establish
that the problem of deciding whether the System can ensure that the probability
to satisfy the mean-payoff parity objective is at least a given threshold is in
NP ∩ coNP, matching the best known bound in the special case of 2-player games
(where all transitions are deterministic) with only parity objectives, or with
only mean-payoff objectives. We present an algorithm running\r\nin time O(d ·
n^{2d}·MeanGame) to compute the set of almost-sure winning states from which the
objective\r\ncan be ensured with probability 1, where n is the number of states
of the game, d the number of priorities\r\nof the parity objective, and MeanGame
is the complexity to compute the set of almost-sure winning states\r\nin 2-1/2-player
mean-payoff games. Our results are useful in the synthesis of stochastic reactive
systems\r\nwith both functional requirement (given as a qualitative objective)
and performance requirement (given\r\nas a quantitative objective)."
alternative_title:
- IST Austria Technical Report
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Laurent
full_name: Doyen, Laurent
last_name: Doyen
- first_name: Hugo
full_name: Gimbert, Hugo
last_name: Gimbert
- first_name: Youssouf
full_name: Oualhadj, Youssouf
last_name: Oualhadj
citation:
ama: Chatterjee K, Doyen L, Gimbert H, Oualhadj Y. Perfect-Information Stochastic
Mean-Payoff Parity Games. IST Austria; 2013. doi:10.15479/AT:IST-2013-128-v1-1
apa: Chatterjee, K., Doyen, L., Gimbert, H., & Oualhadj, Y. (2013). Perfect-information
stochastic mean-payoff parity games. IST Austria. https://doi.org/10.15479/AT:IST-2013-128-v1-1
chicago: Chatterjee, Krishnendu, Laurent Doyen, Hugo Gimbert, and Youssouf Oualhadj.
Perfect-Information Stochastic Mean-Payoff Parity Games. IST Austria, 2013.
https://doi.org/10.15479/AT:IST-2013-128-v1-1.
ieee: K. Chatterjee, L. Doyen, H. Gimbert, and Y. Oualhadj, Perfect-information
stochastic mean-payoff parity games. IST Austria, 2013.
ista: Chatterjee K, Doyen L, Gimbert H, Oualhadj Y. 2013. Perfect-information stochastic
mean-payoff parity games, IST Austria, 22p.
mla: Chatterjee, Krishnendu, et al. Perfect-Information Stochastic Mean-Payoff
Parity Games. IST Austria, 2013, doi:10.15479/AT:IST-2013-128-v1-1.
short: K. Chatterjee, L. Doyen, H. Gimbert, Y. Oualhadj, Perfect-Information Stochastic
Mean-Payoff Parity Games, IST Austria, 2013.
date_created: 2018-12-12T11:39:09Z
date_published: 2013-07-08T00:00:00Z
date_updated: 2023-02-23T10:33:08Z
day: '08'
ddc:
- '000'
- '005'
- '510'
department:
- _id: KrCh
doi: 10.15479/AT:IST-2013-128-v1-1
file:
- access_level: open_access
checksum: ede787a10e74e4f7db302fab8f12f3ca
content_type: application/pdf
creator: system
date_created: 2018-12-12T11:53:54Z
date_updated: 2020-07-14T12:46:45Z
file_id: '5516'
file_name: IST-2013-128-v1+1_full_stoch_mpp.pdf
file_size: 387467
relation: main_file
file_date_updated: 2020-07-14T12:46:45Z
has_accepted_license: '1'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: '22'
publication_identifier:
issn:
- 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '128'
related_material:
record:
- id: '2212'
relation: later_version
status: public
status: public
title: Perfect-information stochastic mean-payoff parity games
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2013'
...
---
_id: '5406'
abstract:
- lang: eng
text: 'We consider the distributed synthesis problem fortemporal logic specifications.
Traditionally, the problem has been studied for LTL, and the previous results
show that the problem is decidable iff there is no information fork in the architecture.
We consider the problem for fragments of LTLand our main results are as follows:
(1) We show that the problem is undecidable for architectures with information
forks even for the fragment of LTL with temporal operators restricted to next
and eventually. (2) For specifications restricted to globally along with non-nested
next operators, we establish decidability (in EXPSPACE) for star architectures
where the processes receive disjoint inputs, whereas we establish undecidability
for architectures containing an information fork-meet structure. (3)Finally, we
consider LTL without the next operator, and establish decidability (NEXPTIME-complete)
for all architectures for a fragment that consists of a set of safety assumptions,
and a set of guarantees where each guarantee is a safety, reachability, or liveness
condition.'
alternative_title:
- IST Austria Technical Report
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Jan
full_name: Otop, Jan
id: 2FC5DA74-F248-11E8-B48F-1D18A9856A87
last_name: Otop
- first_name: Andreas
full_name: Pavlogiannis, Andreas
id: 49704004-F248-11E8-B48F-1D18A9856A87
last_name: Pavlogiannis
orcid: 0000-0002-8943-0722
citation:
ama: Chatterjee K, Henzinger TA, Otop J, Pavlogiannis A. Distributed Synthesis
for LTL Fragments. IST Austria; 2013. doi:10.15479/AT:IST-2013-130-v1-1
apa: Chatterjee, K., Henzinger, T. A., Otop, J., & Pavlogiannis, A. (2013).
Distributed synthesis for LTL Fragments. IST Austria. https://doi.org/10.15479/AT:IST-2013-130-v1-1
chicago: Chatterjee, Krishnendu, Thomas A Henzinger, Jan Otop, and Andreas Pavlogiannis.
Distributed Synthesis for LTL Fragments. IST Austria, 2013. https://doi.org/10.15479/AT:IST-2013-130-v1-1.
ieee: K. Chatterjee, T. A. Henzinger, J. Otop, and A. Pavlogiannis, Distributed
synthesis for LTL Fragments. IST Austria, 2013.
ista: Chatterjee K, Henzinger TA, Otop J, Pavlogiannis A. 2013. Distributed synthesis
for LTL Fragments, IST Austria, 11p.
mla: Chatterjee, Krishnendu, et al. Distributed Synthesis for LTL Fragments.
IST Austria, 2013, doi:10.15479/AT:IST-2013-130-v1-1.
short: K. Chatterjee, T.A. Henzinger, J. Otop, A. Pavlogiannis, Distributed Synthesis
for LTL Fragments, IST Austria, 2013.
date_created: 2018-12-12T11:39:09Z
date_published: 2013-07-08T00:00:00Z
date_updated: 2023-02-21T17:01:26Z
day: '08'
ddc:
- '005'
department:
- _id: KrCh
- _id: ToHe
doi: 10.15479/AT:IST-2013-130-v1-1
file:
- access_level: open_access
checksum: 855513ebaf6f72228800c5fdb522f93c
content_type: application/pdf
creator: system
date_created: 2018-12-12T11:54:18Z
date_updated: 2020-07-14T12:46:45Z
file_id: '5540'
file_name: IST-2013-130-v1+1_Distributed_Synthesis.pdf
file_size: 467895
relation: main_file
file_date_updated: 2020-07-14T12:46:45Z
has_accepted_license: '1'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: '11'
publication_identifier:
issn:
- 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '130'
related_material:
record:
- id: '1376'
relation: later_version
status: public
status: public
title: Distributed synthesis for LTL Fragments
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2013'
...
---
_id: '5408'
abstract:
- lang: eng
text: "We consider two-player partial-observation stochastic games where player
1 has partial observation and player 2 has perfect observation. The winning condition
we study are omega-regular conditions specified as parity objectives. The qualitative
analysis problem given a partial-observation stochastic game and a parity objective
asks whether there is a strategy to ensure that the objective is satisfied with
probability 1 (resp. positive probability). While the qualitative analysis problems
are known to be undecidable even for very special cases of parity objectives,
they were shown to be decidable in 2EXPTIME under finite-memory strategies. We
improve the complexity and show that the qualitative analysis problems for partial-observation
stochastic parity games under finite-memory strategies are \r\nEXPTIME-complete;
and also establish optimal (exponential) memory bounds for finite-memory strategies
required for qualitative analysis. "
alternative_title:
- IST Austria Technical Report
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Laurent
full_name: Doyen, Laurent
last_name: Doyen
- first_name: Sumit
full_name: Nain, Sumit
last_name: Nain
- first_name: Moshe
full_name: Vardi, Moshe
last_name: Vardi
citation:
ama: Chatterjee K, Doyen L, Nain S, Vardi M. The Complexity of Partial-Observation
Stochastic Parity Games with Finite-Memory Strategies. IST Austria; 2013.
doi:10.15479/AT:IST-2013-141-v1-1
apa: Chatterjee, K., Doyen, L., Nain, S., & Vardi, M. (2013). The complexity
of partial-observation stochastic parity games with finite-memory strategies.
IST Austria. https://doi.org/10.15479/AT:IST-2013-141-v1-1
chicago: Chatterjee, Krishnendu, Laurent Doyen, Sumit Nain, and Moshe Vardi. The
Complexity of Partial-Observation Stochastic Parity Games with Finite-Memory Strategies.
IST Austria, 2013. https://doi.org/10.15479/AT:IST-2013-141-v1-1.
ieee: K. Chatterjee, L. Doyen, S. Nain, and M. Vardi, The complexity of partial-observation
stochastic parity games with finite-memory strategies. IST Austria, 2013.
ista: Chatterjee K, Doyen L, Nain S, Vardi M. 2013. The complexity of partial-observation
stochastic parity games with finite-memory strategies, IST Austria, 17p.
mla: Chatterjee, Krishnendu, et al. The Complexity of Partial-Observation Stochastic
Parity Games with Finite-Memory Strategies. IST Austria, 2013, doi:10.15479/AT:IST-2013-141-v1-1.
short: K. Chatterjee, L. Doyen, S. Nain, M. Vardi, The Complexity of Partial-Observation
Stochastic Parity Games with Finite-Memory Strategies, IST Austria, 2013.
date_created: 2018-12-12T11:39:10Z
date_published: 2013-09-12T00:00:00Z
date_updated: 2023-02-23T10:33:11Z
day: '12'
ddc:
- '000'
- '005'
department:
- _id: KrCh
doi: 10.15479/AT:IST-2013-141-v1-1
file:
- access_level: open_access
checksum: 226bc791124f8d3138379778ce834e86
content_type: application/pdf
creator: system
date_created: 2018-12-12T11:53:16Z
date_updated: 2020-07-14T12:46:46Z
file_id: '5477'
file_name: IST-2013-141-v1+1_main-tech-rpt.pdf
file_size: 300481
relation: main_file
file_date_updated: 2020-07-14T12:46:46Z
has_accepted_license: '1'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
page: '17'
publication_identifier:
issn:
- 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '141'
related_material:
record:
- id: '2213'
relation: later_version
status: public
status: public
title: The complexity of partial-observation stochastic parity games with finite-memory
strategies
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2013'
...
---
_id: '5409'
abstract:
- lang: eng
text: "The edit distance between two (untimed) traces is the minimum cost of a sequence
of edit operations (insertion, deletion, or substitution) needed to transform
one trace to the other. Edit distances have been extensively studied in the untimed
setting, and form the basis for approximate matching of sequences in different
domains such as coding theory, parsing, and speech recognition. \r\nIn this paper,
we lift the study of edit distances from untimed languages to the timed setting.
We define an edit distance between timed words which incorporates both the edit
distance between the untimed words and the absolute difference in timestamps.
Our edit distance between two timed words is computable in polynomial time. Further,
we show that the edit distance between a timed word and a timed language generated
by a timed automaton, defined as the edit distance between the word and the closest
word in the language, is PSPACE-complete. While computing the edit distance between
two timed automata is undecidable, we show that the approximate version, where
we decide if the edit distance between two timed automata is either less than
a given parameter or more than delta away from the parameter, for delta>0, can
be solved in exponential space and is EXPSPACE-hard. Our definitions and techniques
can be generalized to the setting of hybrid systems, and we show analogous decidability
results for rectangular automata."
alternative_title:
- IST Austria Technical Report
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Rasmus
full_name: Ibsen-Jensen, Rasmus
id: 3B699956-F248-11E8-B48F-1D18A9856A87
last_name: Ibsen-Jensen
orcid: 0000-0003-4783-0389
- first_name: Rupak
full_name: Majumdar, Rupak
last_name: Majumdar
citation:
ama: Chatterjee K, Ibsen-Jensen R, Majumdar R. Edit Distance for Timed Automata.
IST Austria; 2013. doi:10.15479/AT:IST-2013-144-v1-1
apa: Chatterjee, K., Ibsen-Jensen, R., & Majumdar, R. (2013). Edit distance
for timed automata. IST Austria. https://doi.org/10.15479/AT:IST-2013-144-v1-1
chicago: Chatterjee, Krishnendu, Rasmus Ibsen-Jensen, and Rupak Majumdar. Edit
Distance for Timed Automata. IST Austria, 2013. https://doi.org/10.15479/AT:IST-2013-144-v1-1.
ieee: K. Chatterjee, R. Ibsen-Jensen, and R. Majumdar, Edit distance for timed
automata. IST Austria, 2013.
ista: Chatterjee K, Ibsen-Jensen R, Majumdar R. 2013. Edit distance for timed automata,
IST Austria, 12p.
mla: Chatterjee, Krishnendu, et al. Edit Distance for Timed Automata. IST
Austria, 2013, doi:10.15479/AT:IST-2013-144-v1-1.
short: K. Chatterjee, R. Ibsen-Jensen, R. Majumdar, Edit Distance for Timed Automata,
IST Austria, 2013.
date_created: 2018-12-12T11:39:10Z
date_published: 2013-10-30T00:00:00Z
date_updated: 2023-02-23T10:33:18Z
day: '30'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.15479/AT:IST-2013-144-v1-1
file:
- access_level: open_access
checksum: 0f7633081ba8299c543322f0ad08571f
content_type: application/pdf
creator: system
date_created: 2018-12-12T11:53:08Z
date_updated: 2020-07-14T12:46:46Z
file_id: '5469'
file_name: IST-2013-144-v1+1_main.pdf
file_size: 336377
relation: main_file
file_date_updated: 2020-07-14T12:46:46Z
has_accepted_license: '1'
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
page: '12'
publication_identifier:
issn:
- 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '144'
related_material:
record:
- id: '2216'
relation: later_version
status: public
status: public
title: Edit distance for timed automata
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2013'
...
---
_id: '5410'
abstract:
- lang: eng
text: "Board games, like Tic-Tac-Toe and CONNECT-4, play an important role not only
in development of mathematical and logical skills, but also in emotional and social
development. In this paper, we address the problem of generating targeted starting
positions for such games. This can facilitate new approaches for bringing novice
players to mastery, and also leads to discovery of interesting game variants.
\r\nOur approach generates starting states of varying hardness levels for player
1 in a two-player board game, given rules of the board game, the desired number
of steps required for player 1 to win, and the expertise levels of the two players.
Our approach leverages symbolic methods and iterative simulation to efficiently
search the extremely large state space. We present experimental results that include
discovery of states of varying hardness levels for several simple grid-based board
games. Also, the presence of such states for standard game variants like Tic-Tac-Toe
on board size 4x4 opens up new games to be played that have not been played for
ages since the default start state is heavily biased. "
alternative_title:
- IST Austria Technical Report
author:
- first_name: Umair
full_name: Ahmed, Umair
last_name: Ahmed
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Sumit
full_name: Gulwani, Sumit
last_name: Gulwani
citation:
ama: Ahmed U, Chatterjee K, Gulwani S. Automatic Generation of Alternative Starting
Positions for Traditional Board Games. IST Austria; 2013. doi:10.15479/AT:IST-2013-146-v1-1
apa: Ahmed, U., Chatterjee, K., & Gulwani, S. (2013). Automatic generation
of alternative starting positions for traditional board games. IST Austria.
https://doi.org/10.15479/AT:IST-2013-146-v1-1
chicago: Ahmed, Umair, Krishnendu Chatterjee, and Sumit Gulwani. Automatic Generation
of Alternative Starting Positions for Traditional Board Games. IST Austria,
2013. https://doi.org/10.15479/AT:IST-2013-146-v1-1.
ieee: U. Ahmed, K. Chatterjee, and S. Gulwani, Automatic generation of alternative
starting positions for traditional board games. IST Austria, 2013.
ista: Ahmed U, Chatterjee K, Gulwani S. 2013. Automatic generation of alternative
starting positions for traditional board games, IST Austria, 13p.
mla: Ahmed, Umair, et al. Automatic Generation of Alternative Starting Positions
for Traditional Board Games. IST Austria, 2013, doi:10.15479/AT:IST-2013-146-v1-1.
short: U. Ahmed, K. Chatterjee, S. Gulwani, Automatic Generation of Alternative
Starting Positions for Traditional Board Games, IST Austria, 2013.
date_created: 2018-12-12T11:39:10Z
date_published: 2013-12-03T00:00:00Z
date_updated: 2023-02-23T10:00:50Z
day: '03'
ddc:
- '000'
- '005'
department:
- _id: KrCh
doi: 10.15479/AT:IST-2013-146-v1-1
file:
- access_level: open_access
checksum: 409f3aaaf1184e4057b89cbb449dac80
content_type: application/pdf
creator: system
date_created: 2018-12-12T11:54:06Z
date_updated: 2020-07-14T12:46:46Z
file_id: '5528'
file_name: IST-2013-146-v1+1_main.pdf
file_size: 818189
relation: main_file
file_date_updated: 2020-07-14T12:46:46Z
has_accepted_license: '1'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
page: '13'
publication_identifier:
issn:
- 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '146'
related_material:
record:
- id: '1481'
relation: later_version
status: public
status: public
title: Automatic generation of alternative starting positions for traditional board
games
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2013'
...
---
_id: '5747'
article_processing_charge: No
author:
- first_name: Cezara
full_name: Dragoi, Cezara
id: 2B2B5ED0-F248-11E8-B48F-1D18A9856A87
last_name: Dragoi
- first_name: Ashutosh
full_name: Gupta, Ashutosh
id: 335E5684-F248-11E8-B48F-1D18A9856A87
last_name: Gupta
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
citation:
ama: 'Dragoi C, Gupta A, Henzinger TA. Automatic Linearizability Proofs of Concurrent
Objects with Cooperating Updates. In: Computer Aided Verification. Vol
8044. CAV. Berlin, Heidelberg: Springer Berlin Heidelberg; 2013:174-190. doi:10.1007/978-3-642-39799-8_11'
apa: 'Dragoi, C., Gupta, A., & Henzinger, T. A. (2013). Automatic Linearizability
Proofs of Concurrent Objects with Cooperating Updates. In Computer Aided Verification
(Vol. 8044, pp. 174–190). Berlin, Heidelberg: Springer Berlin Heidelberg. https://doi.org/10.1007/978-3-642-39799-8_11'
chicago: 'Dragoi, Cezara, Ashutosh Gupta, and Thomas A Henzinger. “Automatic Linearizability
Proofs of Concurrent Objects with Cooperating Updates.” In Computer Aided Verification,
8044:174–90. CAV. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. https://doi.org/10.1007/978-3-642-39799-8_11.'
ieee: 'C. Dragoi, A. Gupta, and T. A. Henzinger, “Automatic Linearizability Proofs
of Concurrent Objects with Cooperating Updates,” in Computer Aided Verification,
vol. 8044, Berlin, Heidelberg: Springer Berlin Heidelberg, 2013, pp. 174–190.'
ista: 'Dragoi C, Gupta A, Henzinger TA. 2013.Automatic Linearizability Proofs of
Concurrent Objects with Cooperating Updates. In: Computer Aided Verification.
vol. 8044, 174–190.'
mla: Dragoi, Cezara, et al. “Automatic Linearizability Proofs of Concurrent Objects
with Cooperating Updates.” Computer Aided Verification, vol. 8044, Springer
Berlin Heidelberg, 2013, pp. 174–90, doi:10.1007/978-3-642-39799-8_11.
short: C. Dragoi, A. Gupta, T.A. Henzinger, in:, Computer Aided Verification, Springer
Berlin Heidelberg, Berlin, Heidelberg, 2013, pp. 174–190.
conference:
end_date: 2013-07-19
location: Saint Petersburg, Russia
name: CAV 2013
start_date: 2013-07-13
date_created: 2018-12-18T13:10:21Z
date_published: 2013-01-01T00:00:00Z
date_updated: 2023-09-05T14:16:07Z
ddc:
- '005'
department:
- _id: ToHe
doi: 10.1007/978-3-642-39799-8_11
ec_funded: 1
file:
- access_level: open_access
checksum: a901cc6b71db08b61c0d4c0cbacc6287
content_type: application/pdf
creator: dernst
date_created: 2018-12-18T13:13:33Z
date_updated: 2020-07-14T12:47:10Z
file_id: '5748'
file_name: 2013_CAV_Dragoi.pdf
file_size: 236480
relation: main_file
file_date_updated: 2020-07-14T12:47:10Z
has_accepted_license: '1'
intvolume: ' 8044'
language:
- iso: eng
oa: 1
oa_version: None
page: 174-190
place: Berlin, Heidelberg
project:
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '267989'
name: Quantitative Reactive Modeling
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S 11407_N23
name: Rigorous Systems Engineering
publication: Computer Aided Verification
publication_identifier:
eissn:
- 1611-3349
isbn:
- '9783642397981'
- '9783642397998'
issn:
- 0302-9743
publication_status: published
publisher: Springer Berlin Heidelberg
pubrep_id: '195'
quality_controlled: '1'
scopus_import: '1'
series_title: CAV
status: public
title: Automatic Linearizability Proofs of Concurrent Objects with Cooperating Updates
type: book_chapter
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 8044
year: '2013'
...
---
_id: '6440'
abstract:
- lang: eng
text: In order to guarantee that each method of a data structure updates the logical
state exactly once, al-most all non-blocking implementations employ Compare-And-Swap
(CAS) based synchronization. For FIFO queue implementations this translates into concurrent enqueue or dequeue methods
competing among themselves to update the same variable, the tail or the head,
respectively, leading to high contention and poor scalability. Recent non-blocking
queue implementations try to alleviate high contentionby increasing the number
of contention points, all the while using CAS-based synchronization. Furthermore,
obtaining a wait-free implementation with competition is achieved by additional
synchronization which leads to further degradation of performance.In this paper
we formalize the notion of competitiveness of a synchronizing statement which
can beused as a measure for the scalability of concurrent implementations. We
present a new queue implementation, the Speculative Pairing (SP) queue, which,
as we show, decreases competitiveness by using Fetch-And-Increment (FAI) instead
of CAS. We prove that the SP queue is linearizable and lock-free.We also show
that replacing CAS with FAI leads to wait-freedom for dequeue methods without
an adverse effect on performance. In fact, our experiments suggest that the SP
queue can perform and scale better than the state-of-the-art queue implementations.
alternative_title:
- IST Austria Technical Report
author:
- first_name: Thomas A
full_name: Henzinger, Thomas A
id: 40876CD8-F248-11E8-B48F-1D18A9856A87
last_name: Henzinger
orcid: 0000−0002−2985−7724
- first_name: Hannes
full_name: Payer, Hannes
last_name: Payer
- first_name: Ali
full_name: Sezgin, Ali
id: 4C7638DA-F248-11E8-B48F-1D18A9856A87
last_name: Sezgin
citation:
ama: Henzinger TA, Payer H, Sezgin A. Replacing Competition with Cooperation
to Achieve Scalable Lock-Free FIFO Queues . IST Austria; 2013. doi:10.15479/AT:IST-2013-124-v1-1
apa: Henzinger, T. A., Payer, H., & Sezgin, A. (2013). Replacing competition
with cooperation to achieve scalable lock-free FIFO queues . IST Austria.
https://doi.org/10.15479/AT:IST-2013-124-v1-1
chicago: Henzinger, Thomas A, Hannes Payer, and Ali Sezgin. Replacing Competition
with Cooperation to Achieve Scalable Lock-Free FIFO Queues . IST Austria,
2013. https://doi.org/10.15479/AT:IST-2013-124-v1-1.
ieee: T. A. Henzinger, H. Payer, and A. Sezgin, Replacing competition with cooperation
to achieve scalable lock-free FIFO queues . IST Austria, 2013.
ista: Henzinger TA, Payer H, Sezgin A. 2013. Replacing competition with cooperation
to achieve scalable lock-free FIFO queues , IST Austria, 23p.
mla: Henzinger, Thomas A., et al. Replacing Competition with Cooperation to Achieve
Scalable Lock-Free FIFO Queues . IST Austria, 2013, doi:10.15479/AT:IST-2013-124-v1-1.
short: T.A. Henzinger, H. Payer, A. Sezgin, Replacing Competition with Cooperation
to Achieve Scalable Lock-Free FIFO Queues , IST Austria, 2013.
date_created: 2019-05-13T14:13:27Z
date_published: 2013-06-13T00:00:00Z
date_updated: 2020-07-14T23:06:19Z
day: '13'
ddc:
- '000'
- '005'
department:
- _id: ToHe
doi: 10.15479/AT:IST-2013-124-v1-1
file:
- access_level: open_access
checksum: a219ba4eada6cd62befed52262ee15d4
content_type: application/pdf
creator: dernst
date_created: 2019-05-13T14:11:39Z
date_updated: 2020-07-14T12:47:30Z
file_id: '6441'
file_name: 2013_TechRep_Henzinger.pdf
file_size: 549684
relation: main_file
file_date_updated: 2020-07-14T12:47:30Z
has_accepted_license: '1'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
page: '23'
publication_identifier:
issn:
- 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '124'
status: public
title: 'Replacing competition with cooperation to achieve scalable lock-free FIFO
queues '
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2013'
...
---
_id: '827'
abstract:
- lang: eng
text: As sessile organisms, plants have to be able to adapt to a continuously changing
environment. Plants that perceive some of these changes as stress signals activate
signaling pathways to modulate their development and to enable them to survive.
The complex responses to environmental cues are to a large extent mediated by
plant hormones that together orchestrate the final plant response. The phytohormone
cytokinin is involved in many plant developmental processes. Recently, it has
been established that cytokinin plays an important role in stress responses, but
does not act alone. Indeed, the hormonal control of plant development and stress
adaptation is the outcome of a complex network of multiple synergistic and antagonistic
interactions between various hormones. Here, we review the recent findings on
the cytokinin function as part of this hormonal network. We focus on the importance
of the crosstalk between cytokinin and other hormones, such as abscisic acid,
jasmonate, salicylic acid, ethylene, and auxin in the modulation of plant development
and stress adaptation. Finally, the impact of the current research in the biotechnological
industry will be discussed.
article_number: '451'
author:
- first_name: José
full_name: O'Brien, José
last_name: O'Brien
- first_name: Eva
full_name: Benková, Eva
id: 38F4F166-F248-11E8-B48F-1D18A9856A87
last_name: Benková
orcid: 0000-0002-8510-9739
citation:
ama: O’Brien J, Benková E. Cytokinin cross talking during biotic and abiotic stress
responses. Frontiers in Plant Science. 2013;4. doi:10.3389/fpls.2013.00451
apa: O’Brien, J., & Benková, E. (2013). Cytokinin cross talking during biotic
and abiotic stress responses. Frontiers in Plant Science. Frontiers Research
Foundation. https://doi.org/10.3389/fpls.2013.00451
chicago: O’Brien, José, and Eva Benková. “Cytokinin Cross Talking during Biotic
and Abiotic Stress Responses.” Frontiers in Plant Science. Frontiers Research
Foundation, 2013. https://doi.org/10.3389/fpls.2013.00451.
ieee: J. O’Brien and E. Benková, “Cytokinin cross talking during biotic and abiotic
stress responses,” Frontiers in Plant Science, vol. 4. Frontiers Research
Foundation, 2013.
ista: O’Brien J, Benková E. 2013. Cytokinin cross talking during biotic and abiotic
stress responses. Frontiers in Plant Science. 4, 451.
mla: O’Brien, José, and Eva Benková. “Cytokinin Cross Talking during Biotic and
Abiotic Stress Responses.” Frontiers in Plant Science, vol. 4, 451, Frontiers
Research Foundation, 2013, doi:10.3389/fpls.2013.00451.
short: J. O’Brien, E. Benková, Frontiers in Plant Science 4 (2013).
date_created: 2018-12-11T11:48:43Z
date_published: 2013-11-19T00:00:00Z
date_updated: 2021-01-12T08:17:50Z
day: '19'
ddc:
- '580'
department:
- _id: EvBe
doi: 10.3389/fpls.2013.00451
ec_funded: 1
file:
- access_level: open_access
checksum: fdc25ddd1bf9a99b99f662cdbafeddd4
content_type: application/pdf
creator: dernst
date_created: 2019-01-31T10:40:38Z
date_updated: 2020-07-14T12:48:11Z
file_id: '5903'
file_name: 2013_FrontiersPlant_OBrien.pdf
file_size: 953299
relation: main_file
file_date_updated: 2020-07-14T12:48:11Z
has_accepted_license: '1'
intvolume: ' 4'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
project:
- _id: 253FCA6A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '207362'
name: Hormonal cross-talk in plant organogenesis
publication: Frontiers in Plant Science
publication_status: published
publisher: Frontiers Research Foundation
publist_id: '6821'
quality_controlled: '1'
scopus_import: 1
status: public
title: Cytokinin cross talking during biotic and abiotic stress responses
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 4
year: '2013'
...
---
_id: '828'
abstract:
- lang: eng
text: The plant root system is essential for providing anchorage to the soil, supplying
minerals and water, and synthesizing metabolites. It is a dynamic organ modulated
by external cues such as environmental signals, water and nutrients availability,
salinity and others. Lateral roots (LRs) are initiated from the primary root post-embryonically,
after which they progress through discrete developmental stages which can be independently
controlled, providing a high level of plasticity during root system formation.
Within this review, main contributions are presented, from the classical forward
genetic screens to the more recent high-throughput approaches, combined with computer
model predictions, dissecting how LRs and thereby root system architecture is
established and developed.
article_number: '537'
author:
- first_name: Candela
full_name: Cuesta, Candela
id: 33A3C818-F248-11E8-B48F-1D18A9856A87
last_name: Cuesta
orcid: 0000-0003-1923-2410
- first_name: Krzysztof T
full_name: Wabnik, Krzysztof T
id: 4DE369A4-F248-11E8-B48F-1D18A9856A87
last_name: Wabnik
orcid: 0000-0001-7263-0560
- first_name: Eva
full_name: Benková, Eva
id: 38F4F166-F248-11E8-B48F-1D18A9856A87
last_name: Benková
orcid: 0000-0002-8510-9739
citation:
ama: Cuesta C, Wabnik KT, Benková E. Systems approaches to study root architecture
dynamics. Frontiers in Plant Science. 2013;4. doi:10.3389/fpls.2013.00537
apa: Cuesta, C., Wabnik, K. T., & Benková, E. (2013). Systems approaches to
study root architecture dynamics. Frontiers in Plant Science. Frontiers
Research Foundation. https://doi.org/10.3389/fpls.2013.00537
chicago: Cuesta, Candela, Krzysztof T Wabnik, and Eva Benková. “Systems Approaches
to Study Root Architecture Dynamics.” Frontiers in Plant Science. Frontiers
Research Foundation, 2013. https://doi.org/10.3389/fpls.2013.00537.
ieee: C. Cuesta, K. T. Wabnik, and E. Benková, “Systems approaches to study root
architecture dynamics,” Frontiers in Plant Science, vol. 4. Frontiers Research
Foundation, 2013.
ista: Cuesta C, Wabnik KT, Benková E. 2013. Systems approaches to study root architecture
dynamics. Frontiers in Plant Science. 4, 537.
mla: Cuesta, Candela, et al. “Systems Approaches to Study Root Architecture Dynamics.”
Frontiers in Plant Science, vol. 4, 537, Frontiers Research Foundation,
2013, doi:10.3389/fpls.2013.00537.
short: C. Cuesta, K.T. Wabnik, E. Benková, Frontiers in Plant Science 4 (2013).
date_created: 2018-12-11T11:48:43Z
date_published: 2013-12-26T00:00:00Z
date_updated: 2021-01-12T08:17:52Z
day: '26'
ddc:
- '580'
department:
- _id: EvBe
doi: 10.3389/fpls.2013.00537
ec_funded: 1
file:
- access_level: open_access
checksum: 0185b3c4d7df9a94bd3ce5a66d213506
content_type: application/pdf
creator: dernst
date_created: 2019-01-31T10:36:43Z
date_updated: 2020-07-14T12:48:11Z
file_id: '5902'
file_name: 2013_FrontiersPlant_Cuesta.pdf
file_size: 710835
relation: main_file
file_date_updated: 2020-07-14T12:48:11Z
has_accepted_license: '1'
intvolume: ' 4'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
project:
- _id: 253FCA6A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '207362'
name: Hormonal cross-talk in plant organogenesis
publication: Frontiers in Plant Science
publication_status: published
publisher: Frontiers Research Foundation
publist_id: '6820'
quality_controlled: '1'
scopus_import: 1
status: public
title: Systems approaches to study root architecture dynamics
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 4
year: '2013'
...
---
_id: '9459'
abstract:
- lang: eng
text: Nucleosome remodelers of the DDM1/Lsh family are required for DNA methylation
of transposable elements, but the reason for this is unknown. How DDM1 interacts
with other methylation pathways, such as small-RNA-directed DNA methylation (RdDM),
which is thought to mediate plant asymmetric methylation through DRM enzymes,
is also unclear. Here, we show that most asymmetric methylation is facilitated
by DDM1 and mediated by the methyltransferase CMT2 separately from RdDM. We find
that heterochromatic sequences preferentially require DDM1 for DNA methylation
and that this preference depends on linker histone H1. RdDM is instead inhibited
by heterochromatin and absolutely requires the nucleosome remodeler DRD1. Together,
DDM1 and RdDM mediate nearly all transposon methylation and collaborate to repress
transposition and regulate the methylation and expression of genes. Our results
indicate that DDM1 provides DNA methyltransferases access to H1-containing heterochromatin
to allow stable silencing of transposable elements in cooperation with the RdDM
pathway.
article_processing_charge: No
article_type: original
author:
- first_name: Assaf
full_name: Zemach, Assaf
last_name: Zemach
- first_name: M. Yvonne
full_name: Kim, M. Yvonne
last_name: Kim
- first_name: Ping-Hung
full_name: Hsieh, Ping-Hung
last_name: Hsieh
- first_name: Devin
full_name: Coleman-Derr, Devin
last_name: Coleman-Derr
- first_name: Leor
full_name: Eshed-Williams, Leor
last_name: Eshed-Williams
- first_name: Ka
full_name: Thao, Ka
last_name: Thao
- first_name: Stacey L.
full_name: Harmer, Stacey L.
last_name: Harmer
- first_name: Daniel
full_name: Zilberman, Daniel
id: 6973db13-dd5f-11ea-814e-b3e5455e9ed1
last_name: Zilberman
orcid: 0000-0002-0123-8649
citation:
ama: Zemach A, Kim MY, Hsieh P-H, et al. The Arabidopsis nucleosome remodeler DDM1
allows DNA methyltransferases to access H1-containing heterochromatin. Cell.
2013;153(1):193-205. doi:10.1016/j.cell.2013.02.033
apa: Zemach, A., Kim, M. Y., Hsieh, P.-H., Coleman-Derr, D., Eshed-Williams, L.,
Thao, K., … Zilberman, D. (2013). The Arabidopsis nucleosome remodeler DDM1 allows
DNA methyltransferases to access H1-containing heterochromatin. Cell. Elsevier.
https://doi.org/10.1016/j.cell.2013.02.033
chicago: Zemach, Assaf, M. Yvonne Kim, Ping-Hung Hsieh, Devin Coleman-Derr, Leor
Eshed-Williams, Ka Thao, Stacey L. Harmer, and Daniel Zilberman. “The Arabidopsis
Nucleosome Remodeler DDM1 Allows DNA Methyltransferases to Access H1-Containing
Heterochromatin.” Cell. Elsevier, 2013. https://doi.org/10.1016/j.cell.2013.02.033.
ieee: A. Zemach et al., “The Arabidopsis nucleosome remodeler DDM1 allows
DNA methyltransferases to access H1-containing heterochromatin,” Cell,
vol. 153, no. 1. Elsevier, pp. 193–205, 2013.
ista: Zemach A, Kim MY, Hsieh P-H, Coleman-Derr D, Eshed-Williams L, Thao K, Harmer
SL, Zilberman D. 2013. The Arabidopsis nucleosome remodeler DDM1 allows DNA methyltransferases
to access H1-containing heterochromatin. Cell. 153(1), 193–205.
mla: Zemach, Assaf, et al. “The Arabidopsis Nucleosome Remodeler DDM1 Allows DNA
Methyltransferases to Access H1-Containing Heterochromatin.” Cell, vol.
153, no. 1, Elsevier, 2013, pp. 193–205, doi:10.1016/j.cell.2013.02.033.
short: A. Zemach, M.Y. Kim, P.-H. Hsieh, D. Coleman-Derr, L. Eshed-Williams, K.
Thao, S.L. Harmer, D. Zilberman, Cell 153 (2013) 193–205.
date_created: 2021-06-04T12:23:28Z
date_published: 2013-03-28T00:00:00Z
date_updated: 2021-12-14T08:25:35Z
day: '28'
department:
- _id: DaZi
doi: 10.1016/j.cell.2013.02.033
extern: '1'
external_id:
pmid:
- '23540698'
intvolume: ' 153'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1016/j.cell.2013.02.033
month: '03'
oa: 1
oa_version: Published Version
page: 193-205
pmid: 1
publication: Cell
publication_identifier:
eissn:
- 1097-4172
issn:
- 0092-8674
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: The Arabidopsis nucleosome remodeler DDM1 allows DNA methyltransferases to
access H1-containing heterochromatin
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 153
year: '2013'
...
---
_id: '9481'
abstract:
- lang: eng
text: Arabidopsis thaliana endosperm, a transient tissue that nourishes the embryo,
exhibits extensive localized DNA demethylation on maternally inherited chromosomes.
Demethylation mediates parent-of-origin–specific (imprinted) gene expression but
is apparently unnecessary for the extensive accumulation of maternally biased
small RNA (sRNA) molecules detected in seeds. Endosperm DNA in the distantly related
monocots rice and maize is likewise locally hypomethylated, but whether this hypomethylation
is generally parent-of-origin specific is unknown. Imprinted expression of sRNA
also remains uninvestigated in monocot seeds. Here, we report high-coverage sequencing
of the Kitaake rice cultivar that enabled us to show that localized hypomethylation
in rice endosperm occurs solely on the maternal genome, preferring regions of
high DNA accessibility. Maternally expressed imprinted genes are enriched for
hypomethylation at putative promoter regions and transcriptional termini and paternally
expressed genes at promoters and gene bodies, mirroring our recent results in
A. thaliana. However, unlike in A. thaliana, rice endosperm sRNA populations are
dominated by specific strong sRNA-producing loci, and imprinted 24-nt sRNAs are
expressed from both parental genomes and correlate with hypomethylation. Overlaps
between imprinted sRNA loci and imprinted genes expressed from opposite alleles
suggest that sRNAs may regulate genomic imprinting. Whereas sRNAs in seedling
tissues primarily originate from small class II (cut-and-paste) transposable elements,
those in endosperm are more uniformly derived, including sequences from other
transposon classes, as well as genic and intergenic regions. Our data indicate
that the endosperm exhibits a unique pattern of sRNA expression and suggest that
localized hypomethylation of maternal endosperm DNA is conserved in flowering
plants.
article_processing_charge: No
article_type: original
author:
- first_name: Jessica A.
full_name: Rodrigues, Jessica A.
last_name: Rodrigues
- first_name: Randy
full_name: Ruan, Randy
last_name: Ruan
- first_name: Toshiro
full_name: Nishimura, Toshiro
last_name: Nishimura
- first_name: Manoj K.
full_name: Sharma, Manoj K.
last_name: Sharma
- first_name: Rita
full_name: Sharma, Rita
last_name: Sharma
- first_name: Pamela C
full_name: Ronald, Pamela C
last_name: Ronald
- first_name: Robert L.
full_name: Fischer, Robert L.
last_name: Fischer
- first_name: Daniel
full_name: Zilberman, Daniel
id: 6973db13-dd5f-11ea-814e-b3e5455e9ed1
last_name: Zilberman
orcid: 0000-0002-0123-8649
citation:
ama: Rodrigues JA, Ruan R, Nishimura T, et al. Imprinted expression of genes and
small RNA is associated with localized hypomethylation of the maternal genome
in rice endosperm. Proceedings of the National Academy of Sciences. 2013;110(19):7934-7939.
doi:10.1073/pnas.1306164110
apa: Rodrigues, J. A., Ruan, R., Nishimura, T., Sharma, M. K., Sharma, R., Ronald,
P. C., … Zilberman, D. (2013). Imprinted expression of genes and small RNA is
associated with localized hypomethylation of the maternal genome in rice endosperm.
Proceedings of the National Academy of Sciences. National Academy of Sciences.
https://doi.org/10.1073/pnas.1306164110
chicago: Rodrigues, Jessica A., Randy Ruan, Toshiro Nishimura, Manoj K. Sharma,
Rita Sharma, Pamela C Ronald, Robert L. Fischer, and Daniel Zilberman. “Imprinted
Expression of Genes and Small RNA Is Associated with Localized Hypomethylation
of the Maternal Genome in Rice Endosperm.” Proceedings of the National Academy
of Sciences. National Academy of Sciences, 2013. https://doi.org/10.1073/pnas.1306164110.
ieee: J. A. Rodrigues et al., “Imprinted expression of genes and small RNA
is associated with localized hypomethylation of the maternal genome in rice endosperm,”
Proceedings of the National Academy of Sciences, vol. 110, no. 19. National
Academy of Sciences, pp. 7934–7939, 2013.
ista: Rodrigues JA, Ruan R, Nishimura T, Sharma MK, Sharma R, Ronald PC, Fischer
RL, Zilberman D. 2013. Imprinted expression of genes and small RNA is associated
with localized hypomethylation of the maternal genome in rice endosperm. Proceedings
of the National Academy of Sciences. 110(19), 7934–7939.
mla: Rodrigues, Jessica A., et al. “Imprinted Expression of Genes and Small RNA
Is Associated with Localized Hypomethylation of the Maternal Genome in Rice Endosperm.”
Proceedings of the National Academy of Sciences, vol. 110, no. 19, National
Academy of Sciences, 2013, pp. 7934–39, doi:10.1073/pnas.1306164110.
short: J.A. Rodrigues, R. Ruan, T. Nishimura, M.K. Sharma, R. Sharma, P.C. Ronald,
R.L. Fischer, D. Zilberman, Proceedings of the National Academy of Sciences 110
(2013) 7934–7939.
date_created: 2021-06-07T07:31:02Z
date_published: 2013-05-07T00:00:00Z
date_updated: 2021-12-14T08:26:44Z
day: '07'
department:
- _id: DaZi
doi: 10.1073/pnas.1306164110
extern: '1'
external_id:
pmid:
- '23613580'
intvolume: ' 110'
issue: '19'
keyword:
- Multidisciplinary
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1073/pnas.1306164110
month: '05'
oa: 1
oa_version: Published Version
page: 7934-7939
pmid: 1
publication: Proceedings of the National Academy of Sciences
publication_identifier:
eissn:
- 1091-6490
issn:
- 0027-8424
publication_status: published
publisher: National Academy of Sciences
quality_controlled: '1'
scopus_import: '1'
status: public
title: Imprinted expression of genes and small RNA is associated with localized hypomethylation
of the maternal genome in rice endosperm
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 110
year: '2013'
...
---
_id: '9520'
abstract:
- lang: eng
text: Plants undergo alternation of generation in which reproductive cells develop
in the plant body ("sporophytic generation") and then differentiate into a multicellular
gamete-forming "gametophytic generation." Different populations of helper cells
assist in this transgenerational journey, with somatic tissues supporting early
development and single nurse cells supporting gametogenesis. New data reveal a
two-way relationship between early reproductive cells and their helpers involving
complex epigenetic and signaling networks determining cell number and fate. Later,
the egg cell plays a central role in specifying accessory cells, whereas in both
gametophytes, companion cells contribute non-cell-autonomously to the epigenetic
landscape of the gamete genomes.
article_processing_charge: No
article_type: review
author:
- first_name: Xiaoqi
full_name: Feng, Xiaoqi
id: e0164712-22ee-11ed-b12a-d80fcdf35958
last_name: Feng
orcid: 0000-0002-4008-1234
- first_name: Daniel
full_name: Zilberman, Daniel
id: 6973db13-dd5f-11ea-814e-b3e5455e9ed1
last_name: Zilberman
orcid: 0000-0002-0123-8649
- first_name: Hugh
full_name: Dickinson, Hugh
last_name: Dickinson
citation:
ama: 'Feng X, Zilberman D, Dickinson H. A conversation across generations: Soma-germ
cell crosstalk in plants. Developmental Cell. 2013;24(3):215-225. doi:10.1016/j.devcel.2013.01.014'
apa: 'Feng, X., Zilberman, D., & Dickinson, H. (2013). A conversation across
generations: Soma-germ cell crosstalk in plants. Developmental Cell. Elsevier.
https://doi.org/10.1016/j.devcel.2013.01.014'
chicago: 'Feng, Xiaoqi, Daniel Zilberman, and Hugh Dickinson. “A Conversation across
Generations: Soma-Germ Cell Crosstalk in Plants.” Developmental Cell. Elsevier,
2013. https://doi.org/10.1016/j.devcel.2013.01.014.'
ieee: 'X. Feng, D. Zilberman, and H. Dickinson, “A conversation across generations:
Soma-germ cell crosstalk in plants,” Developmental Cell, vol. 24, no. 3.
Elsevier, pp. 215–225, 2013.'
ista: 'Feng X, Zilberman D, Dickinson H. 2013. A conversation across generations:
Soma-germ cell crosstalk in plants. Developmental Cell. 24(3), 215–225.'
mla: 'Feng, Xiaoqi, et al. “A Conversation across Generations: Soma-Germ Cell Crosstalk
in Plants.” Developmental Cell, vol. 24, no. 3, Elsevier, 2013, pp. 215–25,
doi:10.1016/j.devcel.2013.01.014.'
short: X. Feng, D. Zilberman, H. Dickinson, Developmental Cell 24 (2013) 215–225.
date_created: 2021-06-08T06:14:50Z
date_published: 2013-02-11T00:00:00Z
date_updated: 2023-05-08T11:00:59Z
day: '11'
department:
- _id: DaZi
- _id: XiFe
doi: 10.1016/j.devcel.2013.01.014
extern: '1'
external_id:
pmid:
- '23410937'
intvolume: ' 24'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1016/j.devcel.2013.01.014
month: '02'
oa: 1
oa_version: Published Version
page: 215-225
pmid: 1
publication: Developmental Cell
publication_identifier:
eissn:
- 1878-1551
issn:
- 1534-5807
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'A conversation across generations: Soma-germ cell crosstalk in plants'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 24
year: '2013'
...
---
_id: '9749'
abstract:
- lang: eng
text: Cooperative behavior, where one individual incurs a cost to help another,
is a wide spread phenomenon. Here we study direct reciprocity in the context of
the alternating Prisoner's Dilemma. We consider all strategies that can be implemented
by one and two-state automata. We calculate the payoff matrix of all pairwise
encounters in the presence of noise. We explore deterministic selection dynamics
with and without mutation. Using different error rates and payoff values, we observe
convergence to a small number of distinct equilibria. Two of them are uncooperative
strict Nash equilibria representing always-defect (ALLD) and Grim. The third equilibrium
is mixed and represents a cooperative alliance of several strategies, dominated
by a strategy which we call Forgiver. Forgiver cooperates whenever the opponent
has cooperated; it defects once when the opponent has defected, but subsequently
Forgiver attempts to re-establish cooperation even if the opponent has defected
again. Forgiver is not an evolutionarily stable strategy, but the alliance, which
it rules, is asymptotically stable. For a wide range of parameter values the most
commonly observed outcome is convergence to the mixed equilibrium, dominated by
Forgiver. Our results show that although forgiving might incur a short-term loss
it can lead to a long-term gain. Forgiveness facilitates stable cooperation in
the presence of exploitation and noise.
article_processing_charge: No
author:
- first_name: Benjamin
full_name: Zagorsky, Benjamin
last_name: Zagorsky
- first_name: Johannes
full_name: Reiter, Johannes
id: 4A918E98-F248-11E8-B48F-1D18A9856A87
last_name: Reiter
orcid: 0000-0002-0170-7353
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Martin
full_name: Nowak, Martin
last_name: Nowak
citation:
ama: Zagorsky B, Reiter J, Chatterjee K, Nowak M. Forgiver triumphs in alternating
prisoner’s dilemma . 2013. doi:10.1371/journal.pone.0080814.s001
apa: Zagorsky, B., Reiter, J., Chatterjee, K., & Nowak, M. (2013). Forgiver
triumphs in alternating prisoner’s dilemma . Public Library of Science. https://doi.org/10.1371/journal.pone.0080814.s001
chicago: Zagorsky, Benjamin, Johannes Reiter, Krishnendu Chatterjee, and Martin
Nowak. “Forgiver Triumphs in Alternating Prisoner’s Dilemma .” Public Library
of Science, 2013. https://doi.org/10.1371/journal.pone.0080814.s001.
ieee: B. Zagorsky, J. Reiter, K. Chatterjee, and M. Nowak, “Forgiver triumphs in
alternating prisoner’s dilemma .” Public Library of Science, 2013.
ista: Zagorsky B, Reiter J, Chatterjee K, Nowak M. 2013. Forgiver triumphs in alternating
prisoner’s dilemma , Public Library of Science, 10.1371/journal.pone.0080814.s001.
mla: Zagorsky, Benjamin, et al. Forgiver Triumphs in Alternating Prisoner’s Dilemma
. Public Library of Science, 2013, doi:10.1371/journal.pone.0080814.s001.
short: B. Zagorsky, J. Reiter, K. Chatterjee, M. Nowak, (2013).
date_created: 2021-07-28T15:45:07Z
date_published: 2013-12-12T00:00:00Z
date_updated: 2023-02-23T10:34:39Z
day: '12'
department:
- _id: KrCh
doi: 10.1371/journal.pone.0080814.s001
month: '12'
oa_version: Published Version
publisher: Public Library of Science
related_material:
record:
- id: '2247'
relation: used_in_publication
status: public
status: public
title: 'Forgiver triumphs in alternating prisoner''s dilemma '
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2013'
...
---
_id: '9751'
abstract:
- lang: eng
text: High relatedness among interacting individuals has generally been considered
a precondition for the evolution of altruism. However, kin-selection theory also
predicts the evolution of altruism when relatedness is low, as long as the cost
of the altruistic act is minor compared to its benefit. Here, we demonstrate evidence
for a low-cost altruistic act in bacteria. We investigated Escherichia coli responding
to the attack of an obligately lytic phage by committing suicide in order to prevent
parasite transmission to nearby relatives. We found that bacterial suicide provides
large benefits to survivors at marginal costs to committers. The cost of suicide
was low because infected cells are moribund, rapidly dying upon phage infection,
such that no more opportunity for reproduction remains. As a consequence of its
marginal cost, host suicide was selectively favoured even when relatedness between
committers and survivors approached zero. Altogether, our findings demonstrate
that low-cost suicide can evolve with ease, represents an effective host-defence
strategy, and seems to be widespread among microbes. Moreover, low-cost suicide
might also occur in higher organisms as exemplified by infected social insect
workers leaving the colony to die in isolation.
article_processing_charge: No
author:
- first_name: Dominik
full_name: Refardt, Dominik
last_name: Refardt
- first_name: Tobias
full_name: Bergmiller, Tobias
id: 2C471CFA-F248-11E8-B48F-1D18A9856A87
last_name: Bergmiller
orcid: 0000-0001-5396-4346
- first_name: Rolf
full_name: Kümmerli, Rolf
last_name: Kümmerli
citation:
ama: 'Refardt D, Bergmiller T, Kümmerli R. Data from: Altruism can evolve when relatedness
is low: evidence from bacteria committing suicide upon phage infection. 2013.
doi:10.5061/dryad.b1q2n'
apa: 'Refardt, D., Bergmiller, T., & Kümmerli, R. (2013). Data from: Altruism
can evolve when relatedness is low: evidence from bacteria committing suicide
upon phage infection. Dryad. https://doi.org/10.5061/dryad.b1q2n'
chicago: 'Refardt, Dominik, Tobias Bergmiller, and Rolf Kümmerli. “Data from: Altruism
Can Evolve When Relatedness Is Low: Evidence from Bacteria Committing Suicide
upon Phage Infection.” Dryad, 2013. https://doi.org/10.5061/dryad.b1q2n.'
ieee: 'D. Refardt, T. Bergmiller, and R. Kümmerli, “Data from: Altruism can evolve
when relatedness is low: evidence from bacteria committing suicide upon phage
infection.” Dryad, 2013.'
ista: 'Refardt D, Bergmiller T, Kümmerli R. 2013. Data from: Altruism can evolve
when relatedness is low: evidence from bacteria committing suicide upon phage
infection, Dryad, 10.5061/dryad.b1q2n.'
mla: 'Refardt, Dominik, et al. Data from: Altruism Can Evolve When Relatedness
Is Low: Evidence from Bacteria Committing Suicide upon Phage Infection. Dryad,
2013, doi:10.5061/dryad.b1q2n.'
short: D. Refardt, T. Bergmiller, R. Kümmerli, (2013).
date_created: 2021-07-30T08:08:09Z
date_published: 2013-03-21T00:00:00Z
date_updated: 2023-10-18T06:43:22Z
day: '21'
department:
- _id: CaGu
doi: 10.5061/dryad.b1q2n
main_file_link:
- open_access: '1'
url: https://doi.org/10.5061/dryad.b1q2n
month: '03'
oa: 1
oa_version: Published Version
publisher: Dryad
related_material:
record:
- id: '2853'
relation: used_in_publication
status: public
status: public
title: 'Data from: Altruism can evolve when relatedness is low: evidence from bacteria
committing suicide upon phage infection'
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2013'
...
---
_id: '9754'
abstract:
- lang: eng
text: Short-read sequencing technologies have in principle made it feasible to draw
detailed inferences about the recent history of any organism. In practice, however,
this remains challenging due to the difficulty of genome assembly in most organisms
and the lack of statistical methods powerful enough to discriminate among recent,
non-equilibrium histories. We address both the assembly and inference challenges.
We develop a bioinformatic pipeline for generating outgroup-rooted alignments
of orthologous sequence blocks from de novo low-coverage short-read data for a
small number of genomes, and show how such sequence blocks can be used to fit
explicit models of population divergence and admixture in a likelihood framework.
To illustrate our approach, we reconstruct the Pleistocene history of an oak-feeding
insect (the oak gallwasp Biorhiza pallida) which, in common with many other taxa,
was restricted during Pleistocene ice ages to a longitudinal series of southern
refugia spanning theWestern Palaearctic. Our analysis of sequence blocks sampled
from a single genome from each of three major glacial refugia reveals support
for an unexpected history dominated by recent admixture. Despite the fact that
80% of the genome is affected by admixture during the last glacial cycle, we are
able to infer the deeper divergence history of these populations. These inferences
are robust to variation in block length, mutation model, and the sampling location
of individual genomes within refugia. This combination of de novo assembly and
numerical likelihood calculation provides a powerful framework for estimating
recent population history that can be applied to any organism without the need
for prior genetic resources.
article_processing_charge: No
author:
- first_name: Jack
full_name: Hearn, Jack
last_name: Hearn
- first_name: Graham
full_name: Stone, Graham
last_name: Stone
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
- first_name: Konrad
full_name: Lohse, Konrad
last_name: Lohse
- first_name: Lynsey
full_name: Bunnefeld, Lynsey
last_name: Bunnefeld
citation:
ama: 'Hearn J, Stone G, Barton NH, Lohse K, Bunnefeld L. Data from: Likelihood-based
inference of population history from low coverage de novo genome assemblies. 2013.
doi:10.5061/dryad.r3r60'
apa: 'Hearn, J., Stone, G., Barton, N. H., Lohse, K., & Bunnefeld, L. (2013).
Data from: Likelihood-based inference of population history from low coverage
de novo genome assemblies. Dryad. https://doi.org/10.5061/dryad.r3r60'
chicago: 'Hearn, Jack, Graham Stone, Nicholas H Barton, Konrad Lohse, and Lynsey
Bunnefeld. “Data from: Likelihood-Based Inference of Population History from Low
Coverage de Novo Genome Assemblies.” Dryad, 2013. https://doi.org/10.5061/dryad.r3r60.'
ieee: 'J. Hearn, G. Stone, N. H. Barton, K. Lohse, and L. Bunnefeld, “Data from:
Likelihood-based inference of population history from low coverage de novo genome
assemblies.” Dryad, 2013.'
ista: 'Hearn J, Stone G, Barton NH, Lohse K, Bunnefeld L. 2013. Data from: Likelihood-based
inference of population history from low coverage de novo genome assemblies, Dryad,
10.5061/dryad.r3r60.'
mla: 'Hearn, Jack, et al. Data from: Likelihood-Based Inference of Population
History from Low Coverage de Novo Genome Assemblies. Dryad, 2013, doi:10.5061/dryad.r3r60.'
short: J. Hearn, G. Stone, N.H. Barton, K. Lohse, L. Bunnefeld, (2013).
date_created: 2021-07-30T08:31:22Z
date_published: 2013-10-01T00:00:00Z
date_updated: 2023-02-23T10:31:17Z
day: '01'
department:
- _id: NiBa
doi: 10.5061/dryad.r3r60
main_file_link:
- open_access: '1'
url: https://doi.org/10.5061/dryad.r3r60
month: '10'
oa: 1
oa_version: Published Version
publisher: Dryad
related_material:
record:
- id: '2170'
relation: used_in_publication
status: public
status: public
title: 'Data from: Likelihood-based inference of population history from low coverage
de novo genome assemblies'
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2013'
...
---
_id: '10896'
abstract:
- lang: eng
text: Under physiological conditions the brain, via the purine salvage pathway,
reuses the preformed purine bases hypoxanthine, derived from ATP degradation,
and adenine (Ade), derived from polyamine synthesis, to restore its ATP pool.
However, the massive degradation of ATP during ischemia, although providing valuable
neuroprotective adenosine, results in the accumulation and loss of diffusible
purine metabolites and thereby leads to a protracted reduction in the post-ischemic
ATP pool size. In vivo, this may both limit the ability to deploy ATP-dependent
reparative mechanisms and reduce the subsequent availability of adenosine, whilst
in brain slices results in tissue with substantially lower levels of ATP than
in vivo. In the present review, we describe the mechanisms by which brain tissue
replenishes its ATP, how this can be improved with the clinically tolerated chemicals
D-ribose and adenine, and the functional, and potential therapeutic, implications
of doing so.
acknowledgement: We are grateful to Research into Ageing/Ageing UK and The Dunhill
Trust for funding SzN’s graduate studies, and to Prof Nicholas Dale for his valuable
input.
article_processing_charge: No
author:
- first_name: Stephanie
full_name: zur Nedden, Stephanie
id: 3C77F464-F248-11E8-B48F-1D18A9856A87
last_name: zur Nedden
- first_name: Alexander S.
full_name: Doney, Alexander S.
last_name: Doney
- first_name: Bruno G.
full_name: Frenguelli, Bruno G.
last_name: Frenguelli
citation:
ama: 'zur Nedden S, Doney AS, Frenguelli BG. The double-edged sword: Gaining Adenosine
at the expense of ATP. How to balance the books. In: Masino S, Boison D, eds.
Adenosine. 1st ed. New York: Springer; 2012:109-129. doi:10.1007/978-1-4614-3903-5_6'
apa: 'zur Nedden, S., Doney, A. S., & Frenguelli, B. G. (2012). The double-edged
sword: Gaining Adenosine at the expense of ATP. How to balance the books. In S.
Masino & D. Boison (Eds.), Adenosine (1st ed., pp. 109–129). New York:
Springer. https://doi.org/10.1007/978-1-4614-3903-5_6'
chicago: 'Nedden, Stephanie zur, Alexander S. Doney, and Bruno G. Frenguelli. “The
Double-Edged Sword: Gaining Adenosine at the Expense of ATP. How to Balance the
Books.” In Adenosine, edited by Susan Masino and Detlev Boison, 1st ed.,
109–29. New York: Springer, 2012. https://doi.org/10.1007/978-1-4614-3903-5_6.'
ieee: 'S. zur Nedden, A. S. Doney, and B. G. Frenguelli, “The double-edged sword:
Gaining Adenosine at the expense of ATP. How to balance the books,” in Adenosine,
1st ed., S. Masino and D. Boison, Eds. New York: Springer, 2012, pp. 109–129.'
ista: 'zur Nedden S, Doney AS, Frenguelli BG. 2012.The double-edged sword: Gaining
Adenosine at the expense of ATP. How to balance the books. In: Adenosine. , 109–129.'
mla: 'zur Nedden, Stephanie, et al. “The Double-Edged Sword: Gaining Adenosine at
the Expense of ATP. How to Balance the Books.” Adenosine, edited by Susan
Masino and Detlev Boison, 1st ed., Springer, 2012, pp. 109–29, doi:10.1007/978-1-4614-3903-5_6.'
short: S. zur Nedden, A.S. Doney, B.G. Frenguelli, in:, S. Masino, D. Boison (Eds.),
Adenosine, 1st ed., Springer, New York, 2012, pp. 109–129.
date_created: 2022-03-21T07:16:12Z
date_published: 2012-07-23T00:00:00Z
date_updated: 2022-06-21T11:51:58Z
day: '23'
department:
- _id: HaJa
doi: 10.1007/978-1-4614-3903-5_6
edition: '1'
editor:
- first_name: Susan
full_name: Masino, Susan
last_name: Masino
- first_name: Detlev
full_name: Boison, Detlev
last_name: Boison
language:
- iso: eng
month: '07'
oa_version: None
page: 109-129
place: New York
publication: Adenosine
publication_identifier:
eisbn:
- '9781461439035'
isbn:
- '9781461439028'
publication_status: published
publisher: Springer
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'The double-edged sword: Gaining Adenosine at the expense of ATP. How to balance
the books'
type: book_chapter
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2012'
...
---
_id: '10903'
abstract:
- lang: eng
text: We propose a logic-based framework for automated reasoning about sequential
programs manipulating singly-linked lists and arrays with unbounded data. We introduce
the logic SLAD, which allows combining shape constraints, written in a fragment
of Separation Logic, with data and size constraints. We address the problem of
checking the entailment between SLAD formulas, which is crucial in performing
pre-post condition reasoning. Although this problem is undecidable in general
for SLAD, we propose a sound and powerful procedure that is able to solve this
problem for a large class of formulas, beyond the capabilities of existing techniques
and tools. We prove that this procedure is complete, i.e., it is actually a decision
procedure for this problem, for an important fragment of SLAD including known
decidable logics. We implemented this procedure and shown its preciseness and
its efficiency on a significant benchmark of formulas.
acknowledgement: This work has been partially supported by the French ANR project
Veridyc
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Ahmed
full_name: Bouajjani, Ahmed
last_name: Bouajjani
- first_name: Cezara
full_name: Dragoi, Cezara
id: 2B2B5ED0-F248-11E8-B48F-1D18A9856A87
last_name: Dragoi
- first_name: Constantin
full_name: Enea, Constantin
last_name: Enea
- first_name: Mihaela
full_name: Sighireanu, Mihaela
last_name: Sighireanu
citation:
ama: 'Bouajjani A, Dragoi C, Enea C, Sighireanu M. Accurate invariant checking for
programs manipulating lists and arrays with infinite data. In: Automated Technology
for Verification and Analysis. Vol 7561. LNCS. Berlin, Heidelberg: Springer;
2012:167-182. doi:10.1007/978-3-642-33386-6_14'
apa: 'Bouajjani, A., Dragoi, C., Enea, C., & Sighireanu, M. (2012). Accurate
invariant checking for programs manipulating lists and arrays with infinite data.
In Automated Technology for Verification and Analysis (Vol. 7561, pp. 167–182).
Berlin, Heidelberg: Springer. https://doi.org/10.1007/978-3-642-33386-6_14'
chicago: 'Bouajjani, Ahmed, Cezara Dragoi, Constantin Enea, and Mihaela Sighireanu.
“Accurate Invariant Checking for Programs Manipulating Lists and Arrays with Infinite
Data.” In Automated Technology for Verification and Analysis, 7561:167–82.
LNCS. Berlin, Heidelberg: Springer, 2012. https://doi.org/10.1007/978-3-642-33386-6_14.'
ieee: A. Bouajjani, C. Dragoi, C. Enea, and M. Sighireanu, “Accurate invariant checking
for programs manipulating lists and arrays with infinite data,” in Automated
Technology for Verification and Analysis, Thiruvananthapuram, India, 2012,
vol. 7561, pp. 167–182.
ista: 'Bouajjani A, Dragoi C, Enea C, Sighireanu M. 2012. Accurate invariant checking
for programs manipulating lists and arrays with infinite data. Automated Technology
for Verification and Analysis. ATVA: Automated Technology for Verification and
AnalysisLNCS, LNCS, vol. 7561, 167–182.'
mla: Bouajjani, Ahmed, et al. “Accurate Invariant Checking for Programs Manipulating
Lists and Arrays with Infinite Data.” Automated Technology for Verification
and Analysis, vol. 7561, Springer, 2012, pp. 167–82, doi:10.1007/978-3-642-33386-6_14.
short: A. Bouajjani, C. Dragoi, C. Enea, M. Sighireanu, in:, Automated Technology
for Verification and Analysis, Springer, Berlin, Heidelberg, 2012, pp. 167–182.
conference:
end_date: 2012-10-06
location: Thiruvananthapuram, India
name: 'ATVA: Automated Technology for Verification and Analysis'
start_date: 2012-10-03
date_created: 2022-03-21T07:58:39Z
date_published: 2012-10-15T00:00:00Z
date_updated: 2023-09-05T14:07:24Z
day: '15'
department:
- _id: ToHe
doi: 10.1007/978-3-642-33386-6_14
intvolume: ' 7561'
language:
- iso: eng
month: '10'
oa_version: None
page: 167-182
place: Berlin, Heidelberg
publication: Automated Technology for Verification and Analysis
publication_identifier:
eisbn:
- '9783642333866'
eissn:
- 1611-3349
isbn:
- '9783642333859'
issn:
- 0302-9743
publication_status: published
publisher: Springer
quality_controlled: '1'
scopus_import: '1'
series_title: LNCS
status: public
title: Accurate invariant checking for programs manipulating lists and arrays with
infinite data
type: conference
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 7561
year: '2012'
...