---
_id: '1502'
abstract:
- lang: eng
  text: We extend the theory of input-output conformance with operators for merge
    and quotient. The former is useful when testing against multiple requirements
    or views. The latter can be used to generate tests for patches of an already tested
    system. Both operators can combine systems with different action alphabets, which
    is usually the case when constructing complex systems and specifications from
    parts, for instance different views as well as newly defined functionality of
    a~previous version of the system.
acknowledgement: "This research was funded in part by the European Research Council
  (ERC) under grant agreement 267989 (QUAREM), by the Austrian Science Fund (FWF)
  projects S11402-N23(RiSE) and Z211-N23 (Wittgestein Award), by People Programme
  (Marie Curie Actions) of the European Union's Seventh Framework Programme (FP7/2007-2013)
  under REA grant agreement 291734, and by the ARTEMIS JU under grant agreement 295373
  (nSafeCer).  Jan Křetínský has been partially supported by the Czech Science Foundation,
  grant No.  P202/12/G061.  Nikola Beneš has been supported by the\r\nMEYS project
  No. CZ.1.07/2.3.00/30.0009 Employment of Newly Graduated Doctors of Science for
  Scientific Excellence."
alternative_title:
- 'Proceedings of the 18th International ACM SIGSOFT Symposium on Component-Based
  Software Engineering '
author:
- first_name: Nikola
  full_name: Beneš, Nikola
  last_name: Beneš
- first_name: Przemyslaw
  full_name: Daca, Przemyslaw
  id: 49351290-F248-11E8-B48F-1D18A9856A87
  last_name: Daca
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000−0002−2985−7724
- first_name: Jan
  full_name: Kretinsky, Jan
  id: 44CEF464-F248-11E8-B48F-1D18A9856A87
  last_name: Kretinsky
  orcid: 0000-0002-8122-2881
- first_name: Dejan
  full_name: Nickovic, Dejan
  last_name: Nickovic
citation:
  ama: 'Beneš N, Daca P, Henzinger TA, Kretinsky J, Nickovic D. Complete composition
    operators for IOCO-testing theory. In: ACM; 2015:101-110. doi:<a href="https://doi.org/10.1145/2737166.2737175">10.1145/2737166.2737175</a>'
  apa: 'Beneš, N., Daca, P., Henzinger, T. A., Kretinsky, J., &#38; Nickovic, D. (2015).
    Complete composition operators for IOCO-testing theory (pp. 101–110). Presented
    at the CBSE: Component-Based Software Engineering , Montreal, QC, Canada: ACM.
    <a href="https://doi.org/10.1145/2737166.2737175">https://doi.org/10.1145/2737166.2737175</a>'
  chicago: Beneš, Nikola, Przemyslaw Daca, Thomas A Henzinger, Jan Kretinsky, and
    Dejan Nickovic. “Complete Composition Operators for IOCO-Testing Theory,” 101–10.
    ACM, 2015. <a href="https://doi.org/10.1145/2737166.2737175">https://doi.org/10.1145/2737166.2737175</a>.
  ieee: 'N. Beneš, P. Daca, T. A. Henzinger, J. Kretinsky, and D. Nickovic, “Complete
    composition operators for IOCO-testing theory,” presented at the CBSE: Component-Based
    Software Engineering , Montreal, QC, Canada, 2015, pp. 101–110.'
  ista: 'Beneš N, Daca P, Henzinger TA, Kretinsky J, Nickovic D. 2015. Complete composition
    operators for IOCO-testing theory. CBSE: Component-Based Software Engineering
    , Proceedings of the 18th International ACM SIGSOFT Symposium on Component-Based
    Software Engineering , , 101–110.'
  mla: Beneš, Nikola, et al. <i>Complete Composition Operators for IOCO-Testing Theory</i>.
    ACM, 2015, pp. 101–10, doi:<a href="https://doi.org/10.1145/2737166.2737175">10.1145/2737166.2737175</a>.
  short: N. Beneš, P. Daca, T.A. Henzinger, J. Kretinsky, D. Nickovic, in:, ACM, 2015,
    pp. 101–110.
conference:
  end_date: 2015-05-08
  location: Montreal, QC, Canada
  name: 'CBSE: Component-Based Software Engineering '
  start_date: 2015-05-04
date_created: 2018-12-11T11:52:24Z
date_published: 2015-05-01T00:00:00Z
date_updated: 2023-09-07T11:58:33Z
day: '01'
ddc:
- '000'
department:
- _id: ToHe
- _id: KrCh
doi: 10.1145/2737166.2737175
ec_funded: 1
file:
- access_level: open_access
  checksum: c6ce681035c163a158751f240cb7d389
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:17:46Z
  date_updated: 2020-07-14T12:44:59Z
  file_id: '5303'
  file_name: IST-2016-625-v1+1_conf-cbse-BenesDHKN15.pdf
  file_size: 467561
  relation: main_file
file_date_updated: 2020-07-14T12:44:59Z
has_accepted_license: '1'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Submitted Version
page: 101 - 110
project:
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '267989'
  name: Quantitative Reactive Modeling
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: S 11407_N23
  name: Rigorous Systems Engineering
- _id: 25F42A32-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: Z211
  name: The Wittgenstein Prize
- _id: 25681D80-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '291734'
  name: International IST Postdoc Fellowship Programme
publication_identifier:
  isbn:
  - 978-1-4503-3471-6
publication_status: published
publisher: ACM
publist_id: '5676'
pubrep_id: '625'
quality_controlled: '1'
related_material:
  record:
  - id: '1155'
    relation: dissertation_contains
    status: public
scopus_import: 1
status: public
title: Complete composition operators for IOCO-testing theory
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2015'
...
---
_id: '1505'
abstract:
- lang: eng
  text: This paper is aimed at deriving the universality of the largest eigenvalue
    of a class of high-dimensional real or complex sample covariance matrices of the
    form W N =Σ 1/2XX∗Σ 1/2 . Here, X = (xij )M,N is an M× N random matrix with independent
    entries xij , 1 ≤ i M,≤ 1 ≤ j ≤ N such that Exij = 0, E|xij |2 = 1/N . On dimensionality,
    we assume that M = M(N) and N/M → d ε (0, ∞) as N ∞→. For a class of general deterministic
    positive-definite M × M matrices Σ , under some additional assumptions on the
    distribution of xij 's, we show that the limiting behavior of the largest eigenvalue
    of W N is universal, via pursuing a Green function comparison strategy raised
    in [Probab. Theory Related Fields 154 (2012) 341-407, Adv. Math. 229 (2012) 1435-1515]
    by Erd″os, Yau and Yin for Wigner matrices and extended by Pillai and Yin [Ann.
    Appl. Probab. 24 (2014) 935-1001] to sample covariance matrices in the null case
    (&amp;Epsi = I ). Consequently, in the standard complex case (Ex2 ij = 0), combing
    this universality property and the results known for Gaussian matrices obtained
    by El Karoui in [Ann. Probab. 35 (2007) 663-714] (nonsingular case) and Onatski
    in [Ann. Appl. Probab. 18 (2008) 470-490] (singular case), we show that after
    an appropriate normalization the largest eigenvalue of W N converges weakly to
    the type 2 Tracy-Widom distribution TW2 . Moreover, in the real case, we show
    that whenΣ is spiked with a fixed number of subcritical spikes, the type 1 Tracy-Widom
    limit TW1 holds for the normalized largest eigenvalue of W N , which extends a
    result of Féral and Péché in [J. Math. Phys. 50 (2009) 073302] to the scenario
    of nondiagonal Σ and more generally distributed X . In summary, we establish the
    Tracy-Widom type universality for the largest eigenvalue of generally distributed
    sample covariance matrices under quite light assumptions on &amp;Sigma . Applications
    of these limiting results to statistical signal detection and structure recognition
    of separable covariance matrices are also discussed.
acknowledgement: "B.Z. was supported  in  part  by  NSFC  Grant  11071213,  ZJNSF
  \ Grant  R6090034  and  SRFDP  Grant 20100101110001. P.G. was supported in part
  by the Ministry of Education, Singapore, under Grant ARC 14/11. Z.W. was supported
  \ in  part  by  the  Ministry  of  Education,  Singapore,  under  Grant  ARC  14/11,
  \ and  by a Grant R-155-000-131-112 at the National University of Singapore\r\n"
author:
- first_name: Zhigang
  full_name: Bao, Zhigang
  id: 442E6A6C-F248-11E8-B48F-1D18A9856A87
  last_name: Bao
  orcid: 0000-0003-3036-1475
- first_name: Guangming
  full_name: Pan, Guangming
  last_name: Pan
- first_name: Wang
  full_name: Zhou, Wang
  last_name: Zhou
citation:
  ama: Bao Z, Pan G, Zhou W. Universality for the largest eigenvalue of sample covariance
    matrices with general population. <i>Annals of Statistics</i>. 2015;43(1):382-421.
    doi:<a href="https://doi.org/10.1214/14-AOS1281">10.1214/14-AOS1281</a>
  apa: Bao, Z., Pan, G., &#38; Zhou, W. (2015). Universality for the largest eigenvalue
    of sample covariance matrices with general population. <i>Annals of Statistics</i>.
    Institute of Mathematical Statistics. <a href="https://doi.org/10.1214/14-AOS1281">https://doi.org/10.1214/14-AOS1281</a>
  chicago: Bao, Zhigang, Guangming Pan, and Wang Zhou. “Universality for the Largest
    Eigenvalue of Sample Covariance Matrices with General Population.” <i>Annals of
    Statistics</i>. Institute of Mathematical Statistics, 2015. <a href="https://doi.org/10.1214/14-AOS1281">https://doi.org/10.1214/14-AOS1281</a>.
  ieee: Z. Bao, G. Pan, and W. Zhou, “Universality for the largest eigenvalue of sample
    covariance matrices with general population,” <i>Annals of Statistics</i>, vol.
    43, no. 1. Institute of Mathematical Statistics, pp. 382–421, 2015.
  ista: Bao Z, Pan G, Zhou W. 2015. Universality for the largest eigenvalue of sample
    covariance matrices with general population. Annals of Statistics. 43(1), 382–421.
  mla: Bao, Zhigang, et al. “Universality for the Largest Eigenvalue of Sample Covariance
    Matrices with General Population.” <i>Annals of Statistics</i>, vol. 43, no. 1,
    Institute of Mathematical Statistics, 2015, pp. 382–421, doi:<a href="https://doi.org/10.1214/14-AOS1281">10.1214/14-AOS1281</a>.
  short: Z. Bao, G. Pan, W. Zhou, Annals of Statistics 43 (2015) 382–421.
date_created: 2018-12-11T11:52:25Z
date_published: 2015-02-01T00:00:00Z
date_updated: 2021-01-12T06:51:14Z
day: '01'
department:
- _id: LaEr
doi: 10.1214/14-AOS1281
intvolume: '        43'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1304.5690
month: '02'
oa: 1
oa_version: Preprint
page: 382 - 421
publication: Annals of Statistics
publication_status: published
publisher: Institute of Mathematical Statistics
publist_id: '5672'
quality_controlled: '1'
status: public
title: Universality for the largest eigenvalue of sample covariance matrices with
  general population
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 43
year: '2015'
...
---
_id: '1506'
abstract:
- lang: eng
  text: Consider the square random matrix An = (aij)n,n, where {aij:= a(n)ij , i,
    j = 1, . . . , n} is a collection of independent real random variables with means
    zero and variances one. Under the additional moment condition supn max1≤i,j ≤n
    Ea4ij &lt;∞, we prove Girko's logarithmic law of det An in the sense that as n→∞
    log | detAn| ? (1/2) log(n-1)! d/→√(1/2) log n N(0, 1).
author:
- first_name: Zhigang
  full_name: Bao, Zhigang
  id: 442E6A6C-F248-11E8-B48F-1D18A9856A87
  last_name: Bao
  orcid: 0000-0003-3036-1475
- first_name: Guangming
  full_name: Pan, Guangming
  last_name: Pan
- first_name: Wang
  full_name: Zhou, Wang
  last_name: Zhou
citation:
  ama: Bao Z, Pan G, Zhou W. The logarithmic law of random determinant. <i>Bernoulli</i>.
    2015;21(3):1600-1628. doi:<a href="https://doi.org/10.3150/14-BEJ615">10.3150/14-BEJ615</a>
  apa: Bao, Z., Pan, G., &#38; Zhou, W. (2015). The logarithmic law of random determinant.
    <i>Bernoulli</i>. Bernoulli Society for Mathematical Statistics and Probability.
    <a href="https://doi.org/10.3150/14-BEJ615">https://doi.org/10.3150/14-BEJ615</a>
  chicago: Bao, Zhigang, Guangming Pan, and Wang Zhou. “The Logarithmic Law of Random
    Determinant.” <i>Bernoulli</i>. Bernoulli Society for Mathematical Statistics
    and Probability, 2015. <a href="https://doi.org/10.3150/14-BEJ615">https://doi.org/10.3150/14-BEJ615</a>.
  ieee: Z. Bao, G. Pan, and W. Zhou, “The logarithmic law of random determinant,”
    <i>Bernoulli</i>, vol. 21, no. 3. Bernoulli Society for Mathematical Statistics
    and Probability, pp. 1600–1628, 2015.
  ista: Bao Z, Pan G, Zhou W. 2015. The logarithmic law of random determinant. Bernoulli.
    21(3), 1600–1628.
  mla: Bao, Zhigang, et al. “The Logarithmic Law of Random Determinant.” <i>Bernoulli</i>,
    vol. 21, no. 3, Bernoulli Society for Mathematical Statistics and Probability,
    2015, pp. 1600–28, doi:<a href="https://doi.org/10.3150/14-BEJ615">10.3150/14-BEJ615</a>.
  short: Z. Bao, G. Pan, W. Zhou, Bernoulli 21 (2015) 1600–1628.
date_created: 2018-12-11T11:52:25Z
date_published: 2015-08-01T00:00:00Z
date_updated: 2021-01-12T06:51:14Z
day: '01'
department:
- _id: LaEr
doi: 10.3150/14-BEJ615
intvolume: '        21'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: http://arxiv.org/abs/1208.5823
month: '08'
oa: 1
oa_version: Preprint
page: 1600 - 1628
publication: Bernoulli
publication_status: published
publisher: Bernoulli Society for Mathematical Statistics and Probability
publist_id: '5671'
quality_controlled: '1'
status: public
title: The logarithmic law of random determinant
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 21
year: '2015'
...
---
_id: '1508'
abstract:
- lang: eng
  text: We consider generalized Wigner ensembles and general β-ensembles with analytic
    potentials for any β ≥ 1. The recent universality results in particular assert
    that the local averages of consecutive eigenvalue gaps in the bulk of the spectrum
    are universal in the sense that they coincide with those of the corresponding
    Gaussian β-ensembles. In this article, we show that local averaging is not necessary
    for this result, i.e. we prove that the single gap distributions in the bulk are
    universal. In fact, with an additional step, our result can be extended to any
    C4(ℝ) potential.
author:
- first_name: László
  full_name: Erdös, László
  id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
  last_name: Erdös
  orcid: 0000-0001-5366-9603
- first_name: Horng
  full_name: Yau, Horng
  last_name: Yau
citation:
  ama: Erdös L, Yau H. Gap universality of generalized Wigner and β ensembles. <i>Journal
    of the European Mathematical Society</i>. 2015;17(8):1927-2036. doi:<a href="https://doi.org/10.4171/JEMS/548">10.4171/JEMS/548</a>
  apa: Erdös, L., &#38; Yau, H. (2015). Gap universality of generalized Wigner and
    β ensembles. <i>Journal of the European Mathematical Society</i>. European Mathematical
    Society. <a href="https://doi.org/10.4171/JEMS/548">https://doi.org/10.4171/JEMS/548</a>
  chicago: Erdös, László, and Horng Yau. “Gap Universality of Generalized Wigner and
    β Ensembles.” <i>Journal of the European Mathematical Society</i>. European Mathematical
    Society, 2015. <a href="https://doi.org/10.4171/JEMS/548">https://doi.org/10.4171/JEMS/548</a>.
  ieee: L. Erdös and H. Yau, “Gap universality of generalized Wigner and β ensembles,”
    <i>Journal of the European Mathematical Society</i>, vol. 17, no. 8. European
    Mathematical Society, pp. 1927–2036, 2015.
  ista: Erdös L, Yau H. 2015. Gap universality of generalized Wigner and β ensembles.
    Journal of the European Mathematical Society. 17(8), 1927–2036.
  mla: Erdös, László, and Horng Yau. “Gap Universality of Generalized Wigner and β
    Ensembles.” <i>Journal of the European Mathematical Society</i>, vol. 17, no.
    8, European Mathematical Society, 2015, pp. 1927–2036, doi:<a href="https://doi.org/10.4171/JEMS/548">10.4171/JEMS/548</a>.
  short: L. Erdös, H. Yau, Journal of the European Mathematical Society 17 (2015)
    1927–2036.
date_created: 2018-12-11T11:52:26Z
date_published: 2015-08-01T00:00:00Z
date_updated: 2021-01-12T06:51:15Z
day: '01'
department:
- _id: LaEr
doi: 10.4171/JEMS/548
intvolume: '        17'
issue: '8'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: http://arxiv.org/abs/1211.3786
month: '08'
oa: 1
oa_version: Preprint
page: 1927 - 2036
publication: Journal of the European Mathematical Society
publication_status: published
publisher: European Mathematical Society
publist_id: '5669'
quality_controlled: '1'
scopus_import: 1
status: public
title: Gap universality of generalized Wigner and β ensembles
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 17
year: '2015'
...
---
_id: '1509'
abstract:
- lang: eng
  text: The Auxin Binding Protein1 (ABP1) has been identified based on its ability
    to bind auxin with high affinity and studied for a long time as a prime candidate
    for the extracellular auxin receptor responsible for mediating in particular the
    fast non-transcriptional auxin responses. However, the contradiction between the
    embryo-lethal phenotypes of the originally described Arabidopsis T-DNA insertional
    knock-out alleles (abp1-1 and abp1-1s) and the wild type-like phenotypes of other
    recently described loss-of-function alleles (abp1-c1 and abp1-TD1) questions the
    biological importance of ABP1 and relevance of the previous genetic studies. Here
    we show that there is no hidden copy of the ABP1 gene in the Arabidopsis genome
    but the embryo-lethal phenotypes of abp1-1 and abp1-1s alleles are very similar
    to the knock-out phenotypes of the neighboring gene, BELAYA SMERT (BSM). Furthermore,
    the allelic complementation test between bsm and abp1 alleles shows that the embryo-lethality
    in the abp1-1 and abp1-1s alleles is caused by the off-target disruption of the
    BSM locus by the T-DNA insertions. This clarifies the controversy of different
    phenotypes among published abp1 knock-out alleles and asks for reflections on
    the developmental role of ABP1.
acknowledgement: "This work was supported by ERC Independent Research grant (ERC-2011-StG-20101109-PSDP
  to JF). JM internship was supported by the grant “Action Austria – Slovakia”.\r\nData
  associated with the article are available under the terms of the Creative Commons
  Zero \"No rights reserved\" data waiver (CC0 1.0 Public domain dedication). \r\n\r\nData
  availability: \r\nF1000Research: Dataset 1. Dataset 1, 10.5256/f1000research.7143.d104552\r\n\r\nF1000Research:
  Dataset 2. Dataset 2, 10.5256/f1000research.7143.d104553\r\n\r\nF1000Research: Dataset
  3. Dataset 3, 10.5256/f1000research.7143.d104554"
article_processing_charge: No
author:
- first_name: Jaroslav
  full_name: Michalko, Jaroslav
  id: 483727CA-F248-11E8-B48F-1D18A9856A87
  last_name: Michalko
- first_name: Marta
  full_name: Dravecka, Marta
  id: 4342E402-F248-11E8-B48F-1D18A9856A87
  last_name: Dravecka
  orcid: 0000-0002-2519-8004
- first_name: Tobias
  full_name: Bollenbach, Tobias
  id: 3E6DB97A-F248-11E8-B48F-1D18A9856A87
  last_name: Bollenbach
  orcid: 0000-0003-4398-476X
- first_name: Jirí
  full_name: Friml, Jirí
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
citation:
  ama: Michalko J, Lukacisinova M, Bollenbach MT, Friml J. Embryo-lethal phenotypes
    in early abp1 mutants are due to disruption of the neighboring BSM gene. <i>F1000
    Research </i>. 2015;4. doi:<a href="https://doi.org/10.12688/f1000research.7143.1">10.12688/f1000research.7143.1</a>
  apa: Michalko, J., Lukacisinova, M., Bollenbach, M. T., &#38; Friml, J. (2015).
    Embryo-lethal phenotypes in early abp1 mutants are due to disruption of the neighboring
    BSM gene. <i>F1000 Research </i>. F1000 Research. <a href="https://doi.org/10.12688/f1000research.7143.1">https://doi.org/10.12688/f1000research.7143.1</a>
  chicago: Michalko, Jaroslav, Marta Lukacisinova, Mark Tobias Bollenbach, and Jiří
    Friml. “Embryo-Lethal Phenotypes in Early Abp1 Mutants Are Due to Disruption of
    the Neighboring BSM Gene.” <i>F1000 Research </i>. F1000 Research, 2015. <a href="https://doi.org/10.12688/f1000research.7143.1">https://doi.org/10.12688/f1000research.7143.1</a>.
  ieee: J. Michalko, M. Lukacisinova, M. T. Bollenbach, and J. Friml, “Embryo-lethal
    phenotypes in early abp1 mutants are due to disruption of the neighboring BSM
    gene,” <i>F1000 Research </i>, vol. 4. F1000 Research, 2015.
  ista: Michalko J, Lukacisinova M, Bollenbach MT, Friml J. 2015. Embryo-lethal phenotypes
    in early abp1 mutants are due to disruption of the neighboring BSM gene. F1000
    Research . 4.
  mla: Michalko, Jaroslav, et al. “Embryo-Lethal Phenotypes in Early Abp1 Mutants
    Are Due to Disruption of the Neighboring BSM Gene.” <i>F1000 Research </i>, vol.
    4, F1000 Research, 2015, doi:<a href="https://doi.org/10.12688/f1000research.7143.1">10.12688/f1000research.7143.1</a>.
  short: J. Michalko, M. Lukacisinova, M.T. Bollenbach, J. Friml, F1000 Research  4
    (2015).
date_created: 2018-12-11T11:52:26Z
date_published: 2015-10-01T00:00:00Z
date_updated: 2025-05-07T11:12:30Z
day: '01'
ddc:
- '570'
department:
- _id: JiFr
- _id: ToBo
doi: 10.12688/f1000research.7143.1
ec_funded: 1
file:
- access_level: open_access
  checksum: 8beae5cbe988e1060265ae7de2ee8306
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:16:12Z
  date_updated: 2020-07-14T12:44:59Z
  file_id: '5198'
  file_name: IST-2016-497-v1+1_10.12688_f1000research.7143.1_20151102.pdf
  file_size: 4414248
  relation: main_file
file_date_updated: 2020-07-14T12:44:59Z
has_accepted_license: '1'
intvolume: '         4'
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
project:
- _id: 25716A02-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '282300'
  name: Polarity and subcellular dynamics in plants
publication: 'F1000 Research '
publication_status: published
publisher: F1000 Research
publist_id: '5668'
pubrep_id: '497'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Embryo-lethal phenotypes in early abp1 mutants are due to disruption of the
  neighboring BSM gene
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 4
year: '2015'
...
---
_id: '1510'
abstract:
- lang: eng
  text: 'The concept of well group in a special but important case captures homological
    properties of the zero set of a continuous map f from K to R^n on a compact space
    K that are invariant with respect to perturbations of f. The perturbations are
    arbitrary continuous maps within L_infty distance r from f for a given r &gt;
    0. The main drawback of the approach is that the computability of well groups
    was shown only when dim K = n or n = 1. Our contribution to the theory of well
    groups is twofold: on the one hand we improve on the computability issue, but
    on the other hand we present a range of examples where the well groups are incomplete
    invariants, that is, fail to capture certain important robust properties of the
    zero set. For the first part, we identify a computable subgroup of the well group
    that is obtained by cap product with the pullback of the orientation of R^n by
    f. In other words, well groups can be algorithmically approximated from below.
    When f is smooth and dim K &lt; 2n-2, our approximation of the (dim K-n)th well
    group is exact. For the second part, we find examples of maps f, f'' from K to
    R^n with all well groups isomorphic but whose perturbations have different zero
    sets. We discuss on a possible replacement of the well groups of vector valued
    maps by an invariant of a better descriptive power and computability status. '
alternative_title:
- LIPIcs
author:
- first_name: Peter
  full_name: Franek, Peter
  id: 473294AE-F248-11E8-B48F-1D18A9856A87
  last_name: Franek
- first_name: Marek
  full_name: Krcál, Marek
  id: 33E21118-F248-11E8-B48F-1D18A9856A87
  last_name: Krcál
citation:
  ama: 'Franek P, Krcál M. On computability and triviality of well groups. In: Vol
    34. Schloss Dagstuhl - Leibniz-Zentrum für Informatik; 2015:842-856. doi:<a href="https://doi.org/10.4230/LIPIcs.SOCG.2015.842">10.4230/LIPIcs.SOCG.2015.842</a>'
  apa: 'Franek, P., &#38; Krcál, M. (2015). On computability and triviality of well
    groups (Vol. 34, pp. 842–856). Presented at the SoCG: Symposium on Computational
    Geometry, Eindhoven, Netherlands: Schloss Dagstuhl - Leibniz-Zentrum für Informatik.
    <a href="https://doi.org/10.4230/LIPIcs.SOCG.2015.842">https://doi.org/10.4230/LIPIcs.SOCG.2015.842</a>'
  chicago: Franek, Peter, and Marek Krcál. “On Computability and Triviality of Well
    Groups,” 34:842–56. Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2015. <a
    href="https://doi.org/10.4230/LIPIcs.SOCG.2015.842">https://doi.org/10.4230/LIPIcs.SOCG.2015.842</a>.
  ieee: 'P. Franek and M. Krcál, “On computability and triviality of well groups,”
    presented at the SoCG: Symposium on Computational Geometry, Eindhoven, Netherlands,
    2015, vol. 34, pp. 842–856.'
  ista: 'Franek P, Krcál M. 2015. On computability and triviality of well groups.
    SoCG: Symposium on Computational Geometry, LIPIcs, vol. 34, 842–856.'
  mla: Franek, Peter, and Marek Krcál. <i>On Computability and Triviality of Well
    Groups</i>. Vol. 34, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2015,
    pp. 842–56, doi:<a href="https://doi.org/10.4230/LIPIcs.SOCG.2015.842">10.4230/LIPIcs.SOCG.2015.842</a>.
  short: P. Franek, M. Krcál, in:, Schloss Dagstuhl - Leibniz-Zentrum für Informatik,
    2015, pp. 842–856.
conference:
  end_date: 2015-06-25
  location: Eindhoven, Netherlands
  name: 'SoCG: Symposium on Computational Geometry'
  start_date: 2015-06-22
date_created: 2018-12-11T11:52:26Z
date_published: 2015-06-11T00:00:00Z
date_updated: 2023-02-21T17:02:57Z
day: '11'
ddc:
- '510'
department:
- _id: UlWa
- _id: HeEd
doi: 10.4230/LIPIcs.SOCG.2015.842
ec_funded: 1
file:
- access_level: open_access
  checksum: 49eb5021caafaabe5356c65b9c5f8c9c
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:13:19Z
  date_updated: 2020-07-14T12:44:59Z
  file_id: '5001'
  file_name: IST-2016-503-v1+1_32.pdf
  file_size: 623563
  relation: main_file
file_date_updated: 2020-07-14T12:44:59Z
has_accepted_license: '1'
intvolume: '        34'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
page: 842 - 856
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '291734'
  name: International IST Postdoc Fellowship Programme
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
publist_id: '5667'
pubrep_id: '503'
quality_controlled: '1'
related_material:
  record:
  - id: '1408'
    relation: later_version
    status: public
scopus_import: 1
status: public
title: On computability and triviality of well groups
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 34
year: '2015'
...
---
_id: '1511'
abstract:
- lang: eng
  text: 'The fact that the complete graph K_5 does not embed in the plane has been
    generalized in two independent directions. On the one hand, the solution of the
    classical Heawood problem for graphs on surfaces established that the complete
    graph K_n embeds in a closed surface M if and only if (n-3)(n-4) is at most 6b_1(M),
    where b_1(M) is the first Z_2-Betti number of M. On the other hand, Van Kampen
    and Flores proved that the k-skeleton of the n-dimensional simplex (the higher-dimensional
    analogue of K_{n+1}) embeds in R^{2k} if and only if n is less or equal to 2k+2.
    Two decades ago, Kuhnel conjectured that the k-skeleton of the n-simplex embeds
    in a compact, (k-1)-connected 2k-manifold with kth Z_2-Betti number b_k only if
    the following generalized Heawood inequality holds: binom{n-k-1}{k+1} is at most
    binom{2k+1}{k+1} b_k. This is a common generalization of the case of graphs on
    surfaces as well as the Van Kampen--Flores theorem. In the spirit of Kuhnel''s
    conjecture, we prove that if the k-skeleton of the n-simplex embeds in a 2k-manifold
    with kth Z_2-Betti number b_k, then n is at most 2b_k binom{2k+2}{k} + 2k + 5.
    This bound is weaker than the generalized Heawood inequality, but does not require
    the assumption that M is (k-1)-connected. Our proof uses a result of Volovikov
    about maps that satisfy a certain homological triviality condition.'
acknowledgement: "The work by Z. P. was partially supported by the Charles University
  Grant SVV-2014-260103. The\r\nwork by Z. P. and M. T. was partially supported by
  the project CE-ITI (GACR P202/12/G061) of\r\nthe Czech Science Foundation and by
  the ERC Advanced Grant No. 267165. Part of the research\r\nwork of M. T. was conducted
  at IST Austria, supported by an IST Fellowship. The work by U.W.\r\nwas partially
  supported by the Swiss National Science Foundation (grants SNSF-200020-138230 and\r\nSNSF-PP00P2-138948)."
alternative_title:
- LIPIcs
author:
- first_name: Xavier
  full_name: Goaoc, Xavier
  last_name: Goaoc
- first_name: Isaac
  full_name: Mabillard, Isaac
  id: 32BF9DAA-F248-11E8-B48F-1D18A9856A87
  last_name: Mabillard
- first_name: Pavel
  full_name: Paták, Pavel
  last_name: Paták
- first_name: Zuzana
  full_name: Patakova, Zuzana
  id: 48B57058-F248-11E8-B48F-1D18A9856A87
  last_name: Patakova
  orcid: 0000-0002-3975-1683
- first_name: Martin
  full_name: Tancer, Martin
  id: 38AC689C-F248-11E8-B48F-1D18A9856A87
  last_name: Tancer
  orcid: 0000-0002-1191-6714
- first_name: Uli
  full_name: Wagner, Uli
  id: 36690CA2-F248-11E8-B48F-1D18A9856A87
  last_name: Wagner
  orcid: 0000-0002-1494-0568
citation:
  ama: 'Goaoc X, Mabillard I, Paták P, Patakova Z, Tancer M, Wagner U. On generalized
    Heawood inequalities for manifolds: A Van Kampen–Flores-type nonembeddability
    result. In: Vol 34. Schloss Dagstuhl - Leibniz-Zentrum für Informatik; 2015:476-490.
    doi:<a href="https://doi.org/10.4230/LIPIcs.SOCG.2015.476">10.4230/LIPIcs.SOCG.2015.476</a>'
  apa: 'Goaoc, X., Mabillard, I., Paták, P., Patakova, Z., Tancer, M., &#38; Wagner,
    U. (2015). On generalized Heawood inequalities for manifolds: A Van Kampen–Flores-type
    nonembeddability result (Vol. 34, pp. 476–490). Presented at the SoCG: Symposium
    on Computational Geometry, Eindhoven, Netherlands: Schloss Dagstuhl - Leibniz-Zentrum
    für Informatik. <a href="https://doi.org/10.4230/LIPIcs.SOCG.2015.476">https://doi.org/10.4230/LIPIcs.SOCG.2015.476</a>'
  chicago: 'Goaoc, Xavier, Isaac Mabillard, Pavel Paták, Zuzana Patakova, Martin Tancer,
    and Uli Wagner. “On Generalized Heawood Inequalities for Manifolds: A Van Kampen–Flores-Type
    Nonembeddability Result,” 34:476–90. Schloss Dagstuhl - Leibniz-Zentrum für Informatik,
    2015. <a href="https://doi.org/10.4230/LIPIcs.SOCG.2015.476">https://doi.org/10.4230/LIPIcs.SOCG.2015.476</a>.'
  ieee: 'X. Goaoc, I. Mabillard, P. Paták, Z. Patakova, M. Tancer, and U. Wagner,
    “On generalized Heawood inequalities for manifolds: A Van Kampen–Flores-type nonembeddability
    result,” presented at the SoCG: Symposium on Computational Geometry, Eindhoven,
    Netherlands, 2015, vol. 34, pp. 476–490.'
  ista: 'Goaoc X, Mabillard I, Paták P, Patakova Z, Tancer M, Wagner U. 2015. On generalized
    Heawood inequalities for manifolds: A Van Kampen–Flores-type nonembeddability
    result. SoCG: Symposium on Computational Geometry, LIPIcs, vol. 34, 476–490.'
  mla: 'Goaoc, Xavier, et al. <i>On Generalized Heawood Inequalities for Manifolds:
    A Van Kampen–Flores-Type Nonembeddability Result</i>. Vol. 34, Schloss Dagstuhl
    - Leibniz-Zentrum für Informatik, 2015, pp. 476–90, doi:<a href="https://doi.org/10.4230/LIPIcs.SOCG.2015.476">10.4230/LIPIcs.SOCG.2015.476</a>.'
  short: X. Goaoc, I. Mabillard, P. Paták, Z. Patakova, M. Tancer, U. Wagner, in:,
    Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2015, pp. 476–490.
conference:
  end_date: 2015-06-25
  location: Eindhoven, Netherlands
  name: 'SoCG: Symposium on Computational Geometry'
  start_date: 2015-06-22
date_created: 2018-12-11T11:52:27Z
date_published: 2015-06-11T00:00:00Z
date_updated: 2023-02-23T12:38:00Z
day: '11'
ddc:
- '510'
department:
- _id: UlWa
doi: 10.4230/LIPIcs.SOCG.2015.476
ec_funded: 1
file:
- access_level: open_access
  checksum: 0945811875351796324189312ca29e9e
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:11:18Z
  date_updated: 2020-07-14T12:44:59Z
  file_id: '4871'
  file_name: IST-2016-502-v1+1_42.pdf
  file_size: 636735
  relation: main_file
file_date_updated: 2020-07-14T12:44:59Z
has_accepted_license: '1'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
page: 476 - 490
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '291734'
  name: International IST Postdoc Fellowship Programme
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
publist_id: '5666'
pubrep_id: '502'
quality_controlled: '1'
related_material:
  record:
  - id: '610'
    relation: later_version
    status: public
scopus_import: 1
status: public
title: 'On generalized Heawood inequalities for manifolds: A Van Kampen–Flores-type
  nonembeddability result'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: '34 '
year: '2015'
...
---
_id: '1512'
abstract:
- lang: eng
  text: 'We show that very weak topological assumptions are enough to ensure the existence
    of a Helly-type theorem. More precisely, we show that for any non-negative integers
    b and d there exists an integer h(b,d) such that the following holds. If F is
    a finite family of subsets of R^d such that the ith reduced Betti number (with
    Z_2 coefficients in singular homology) of the intersection of any proper subfamily
    G of F is at most b for every non-negative integer i less or equal to (d-1)/2,
    then F has Helly number at most h(b,d). These topological conditions are sharp:
    not controlling any of these first Betti numbers allow for families with unbounded
    Helly number. Our proofs combine homological non-embeddability results with a
    Ramsey-based approach to build, given an arbitrary simplicial complex K, some
    well-behaved chain map from C_*(K) to C_*(R^d). Both techniques are of independent
    interest.'
acknowledgement: "PP, ZP and MT were partially supported by the Charles University
  Grant GAUK 421511. ZP was\r\npartially supported by the Charles University Grant
  SVV-2014-260103. ZP and MT were partially\r\nsupported by the ERC Advanced Grant
  No. 267165 and by the project CE-ITI (GACR P202/12/G061)\r\nof the Czech Science
  Foundation. UW was partially supported by the Swiss National Science Foundation\r\n(grants
  SNSF-200020-138230 and SNSF-PP00P2-138948). Part of this work was done when XG was
  affiliated with INRIA Nancy Grand-Est and when MT was affiliated with Institutionen
  för matematik, Kungliga Tekniska Högskolan, then IST Austria."
alternative_title:
- LIPIcs
article_processing_charge: No
author:
- first_name: Xavier
  full_name: Goaoc, Xavier
  last_name: Goaoc
- first_name: Pavel
  full_name: Paták, Pavel
  last_name: Paták
- first_name: Zuzana
  full_name: Patakova, Zuzana
  last_name: Patakova
  orcid: 0000-0002-3975-1683
- first_name: Martin
  full_name: Tancer, Martin
  last_name: Tancer
  orcid: 0000-0002-1191-6714
- first_name: Uli
  full_name: Wagner, Uli
  id: 36690CA2-F248-11E8-B48F-1D18A9856A87
  last_name: Wagner
  orcid: 0000-0002-1494-0568
citation:
  ama: 'Goaoc X, Paták P, Patakova Z, Tancer M, Wagner U. Bounding Helly numbers via
    Betti numbers. In: Vol 34. Schloss Dagstuhl - Leibniz-Zentrum für Informatik;
    2015:507-521. doi:<a href="https://doi.org/10.4230/LIPIcs.SOCG.2015.507">10.4230/LIPIcs.SOCG.2015.507</a>'
  apa: 'Goaoc, X., Paták, P., Patakova, Z., Tancer, M., &#38; Wagner, U. (2015). Bounding
    Helly numbers via Betti numbers (Vol. 34, pp. 507–521). Presented at the SoCG:
    Symposium on Computational Geometry, Eindhoven, Netherlands: Schloss Dagstuhl
    - Leibniz-Zentrum für Informatik. <a href="https://doi.org/10.4230/LIPIcs.SOCG.2015.507">https://doi.org/10.4230/LIPIcs.SOCG.2015.507</a>'
  chicago: Goaoc, Xavier, Pavel Paták, Zuzana Patakova, Martin Tancer, and Uli Wagner.
    “Bounding Helly Numbers via Betti Numbers,” 34:507–21. Schloss Dagstuhl - Leibniz-Zentrum
    für Informatik, 2015. <a href="https://doi.org/10.4230/LIPIcs.SOCG.2015.507">https://doi.org/10.4230/LIPIcs.SOCG.2015.507</a>.
  ieee: 'X. Goaoc, P. Paták, Z. Patakova, M. Tancer, and U. Wagner, “Bounding Helly
    numbers via Betti numbers,” presented at the SoCG: Symposium on Computational
    Geometry, Eindhoven, Netherlands, 2015, vol. 34, pp. 507–521.'
  ista: 'Goaoc X, Paták P, Patakova Z, Tancer M, Wagner U. 2015. Bounding Helly numbers
    via Betti numbers. SoCG: Symposium on Computational Geometry, LIPIcs, vol. 34,
    507–521.'
  mla: Goaoc, Xavier, et al. <i>Bounding Helly Numbers via Betti Numbers</i>. Vol.
    34, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2015, pp. 507–21, doi:<a
    href="https://doi.org/10.4230/LIPIcs.SOCG.2015.507">10.4230/LIPIcs.SOCG.2015.507</a>.
  short: X. Goaoc, P. Paták, Z. Patakova, M. Tancer, U. Wagner, in:, Schloss Dagstuhl
    - Leibniz-Zentrum für Informatik, 2015, pp. 507–521.
conference:
  end_date: 2015-06-25
  location: Eindhoven, Netherlands
  name: 'SoCG: Symposium on Computational Geometry'
  start_date: 2015-06-22
date_created: 2018-12-11T11:52:27Z
date_published: 2015-01-01T00:00:00Z
date_updated: 2024-02-28T12:59:37Z
day: '01'
ddc:
- '510'
department:
- _id: UlWa
doi: 10.4230/LIPIcs.SOCG.2015.507
file:
- access_level: open_access
  checksum: e6881df44d87fe0c2529c9f7b2724614
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:10:09Z
  date_updated: 2020-07-14T12:45:00Z
  file_id: '4794'
  file_name: IST-2016-501-v1+1_46.pdf
  file_size: 633712
  relation: main_file
file_date_updated: 2020-07-14T12:45:00Z
has_accepted_license: '1'
intvolume: '        34'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Submitted Version
page: 507 - 521
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
publist_id: '5665'
pubrep_id: '501'
quality_controlled: '1'
related_material:
  record:
  - id: '424'
    relation: later_version
    status: public
scopus_import: '1'
status: public
title: Bounding Helly numbers via Betti numbers
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 34
year: '2015'
...
---
_id: '1513'
abstract:
- lang: eng
  text: "Insects of the order Hemiptera (true bugs) use a wide range of mechanisms
    of sex determination, including genetic sex determination, paternal genome elimination,
    and haplodiploidy. Genetic sex determination, the prevalent mode, is generally
    controlled by a pair of XY sex chromosomes or by an XX/X0 system, but different
    configurations that include additional sex chromosomes are also present. Although
    this diversity of sex determining systems has been extensively studied at the
    cytogenetic level, only the X chromosome of the model pea aphid Acyrthosiphon
    pisum has been analyzed at the genomic level, and little is known about X chromosome
    biology in the rest of the order.\r\n\r\nIn this study, we take advantage of published
    DNA- and RNA-seq data from three additional Hemiptera species to perform a comparative
    analysis of the gene content and expression of the X chromosome throughout this
    clade. We find that, despite showing evidence of dosage compensation, the X chromosomes
    of these species show female-biased expression, and a deficit of male-biased genes,
    in direct contrast to the pea aphid X. We further detect an excess of shared gene
    content between these very distant species, suggesting that despite the diversity
    of sex determining systems, the same chromosomal element is used as the X throughout
    a large portion of the order. "
article_processing_charge: No
author:
- first_name: Arka
  full_name: Pal, Arka
  id: 6AAB2240-CA9A-11E9-9C1A-D9D1E5697425
  last_name: Pal
- first_name: Beatriz
  full_name: Vicoso, Beatriz
  id: 49E1C5C6-F248-11E8-B48F-1D18A9856A87
  last_name: Vicoso
  orcid: 0000-0002-4579-8306
citation:
  ama: 'Pal A, Vicoso B. The X chromosome of hemipteran insects: Conservation, dosage
    compensation and sex-biased expression. <i>Genome Biology and Evolution</i>. 2015;7(12):3259-3268.
    doi:<a href="https://doi.org/10.1093/gbe/evv215">10.1093/gbe/evv215</a>'
  apa: 'Pal, A., &#38; Vicoso, B. (2015). The X chromosome of hemipteran insects:
    Conservation, dosage compensation and sex-biased expression. <i>Genome Biology
    and Evolution</i>. Oxford University Press. <a href="https://doi.org/10.1093/gbe/evv215">https://doi.org/10.1093/gbe/evv215</a>'
  chicago: 'Pal, Arka, and Beatriz Vicoso. “The X Chromosome of Hemipteran Insects:
    Conservation, Dosage Compensation and Sex-Biased Expression.” <i>Genome Biology
    and Evolution</i>. Oxford University Press, 2015. <a href="https://doi.org/10.1093/gbe/evv215">https://doi.org/10.1093/gbe/evv215</a>.'
  ieee: 'A. Pal and B. Vicoso, “The X chromosome of hemipteran insects: Conservation,
    dosage compensation and sex-biased expression,” <i>Genome Biology and Evolution</i>,
    vol. 7, no. 12. Oxford University Press, pp. 3259–3268, 2015.'
  ista: 'Pal A, Vicoso B. 2015. The X chromosome of hemipteran insects: Conservation,
    dosage compensation and sex-biased expression. Genome Biology and Evolution. 7(12),
    3259–3268.'
  mla: 'Pal, Arka, and Beatriz Vicoso. “The X Chromosome of Hemipteran Insects: Conservation,
    Dosage Compensation and Sex-Biased Expression.” <i>Genome Biology and Evolution</i>,
    vol. 7, no. 12, Oxford University Press, 2015, pp. 3259–68, doi:<a href="https://doi.org/10.1093/gbe/evv215">10.1093/gbe/evv215</a>.'
  short: A. Pal, B. Vicoso, Genome Biology and Evolution 7 (2015) 3259–3268.
date_created: 2018-12-11T11:52:27Z
date_published: 2015-12-01T00:00:00Z
date_updated: 2021-01-12T06:51:18Z
day: '01'
ddc:
- '570'
department:
- _id: BeVi
doi: 10.1093/gbe/evv215
ec_funded: 1
file:
- access_level: open_access
  checksum: 2b56b8c2e2a1d4cc3c9cb8daba26dd9b
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:17:29Z
  date_updated: 2020-07-14T12:45:00Z
  file_id: '5284'
  file_name: IST-2016-496-v1+1_Genome_Biol_Evol-2015-Pal-3259-68.pdf
  file_size: 858027
  relation: main_file
file_date_updated: 2020-07-14T12:45:00Z
has_accepted_license: '1'
intvolume: '         7'
issue: '12'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
page: 3259 - 3268
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '291734'
  name: International IST Postdoc Fellowship Programme
publication: Genome Biology and Evolution
publication_status: published
publisher: Oxford University Press
publist_id: '5664'
pubrep_id: '496'
quality_controlled: '1'
scopus_import: 1
status: public
title: 'The X chromosome of hemipteran insects: Conservation, dosage compensation
  and sex-biased expression'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 7
year: '2015'
...
---
_id: '1517'
abstract:
- lang: eng
  text: "We study the large deviation rate functional for the empirical distribution
    of independent Brownian particles with drift. In one dimension, it has been shown
    by Adams, Dirr, Peletier and Zimmer that this functional is asymptotically equivalent
    (in the sense of Γ-convergence) to the Jordan-Kinderlehrer-Otto functional arising
    in the Wasserstein gradient flow structure of the Fokker-Planck equation. In higher
    dimensions, part of this statement (the lower bound) has been recently proved
    by Duong, Laschos and Renger, but the upper bound remained open, since the proof
    of Duong et al relies on regularity properties of optimal transport maps that
    are restricted to one dimension. In this note we present a new proof of the upper
    bound, thereby generalising the result of Adams et al to arbitrary dimensions.\r\n"
article_number: '89'
author:
- first_name: Matthias
  full_name: Erbar, Matthias
  last_name: Erbar
- first_name: Jan
  full_name: Maas, Jan
  id: 4C5696CE-F248-11E8-B48F-1D18A9856A87
  last_name: Maas
  orcid: 0000-0002-0845-1338
- first_name: Michiel
  full_name: Renger, Michiel
  last_name: Renger
citation:
  ama: Erbar M, Maas J, Renger M. From large deviations to Wasserstein gradient flows
    in multiple dimensions. <i>Electronic Communications in Probability</i>. 2015;20.
    doi:<a href="https://doi.org/10.1214/ECP.v20-4315">10.1214/ECP.v20-4315</a>
  apa: Erbar, M., Maas, J., &#38; Renger, M. (2015). From large deviations to Wasserstein
    gradient flows in multiple dimensions. <i>Electronic Communications in Probability</i>.
    Institute of Mathematical Statistics. <a href="https://doi.org/10.1214/ECP.v20-4315">https://doi.org/10.1214/ECP.v20-4315</a>
  chicago: Erbar, Matthias, Jan Maas, and Michiel Renger. “From Large Deviations to
    Wasserstein Gradient Flows in Multiple Dimensions.” <i>Electronic Communications
    in Probability</i>. Institute of Mathematical Statistics, 2015. <a href="https://doi.org/10.1214/ECP.v20-4315">https://doi.org/10.1214/ECP.v20-4315</a>.
  ieee: M. Erbar, J. Maas, and M. Renger, “From large deviations to Wasserstein gradient
    flows in multiple dimensions,” <i>Electronic Communications in Probability</i>,
    vol. 20. Institute of Mathematical Statistics, 2015.
  ista: Erbar M, Maas J, Renger M. 2015. From large deviations to Wasserstein gradient
    flows in multiple dimensions. Electronic Communications in Probability. 20, 89.
  mla: Erbar, Matthias, et al. “From Large Deviations to Wasserstein Gradient Flows
    in Multiple Dimensions.” <i>Electronic Communications in Probability</i>, vol.
    20, 89, Institute of Mathematical Statistics, 2015, doi:<a href="https://doi.org/10.1214/ECP.v20-4315">10.1214/ECP.v20-4315</a>.
  short: M. Erbar, J. Maas, M. Renger, Electronic Communications in Probability 20
    (2015).
date_created: 2018-12-11T11:52:29Z
date_published: 2015-11-29T00:00:00Z
date_updated: 2021-01-12T06:51:19Z
day: '29'
ddc:
- '519'
department:
- _id: JaMa
doi: 10.1214/ECP.v20-4315
file:
- access_level: open_access
  checksum: 135741c17d3e1547ca696b6fbdcd559c
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:10:39Z
  date_updated: 2020-07-14T12:45:00Z
  file_id: '4828'
  file_name: IST-2016-494-v1+1_4315-23820-1-PB.pdf
  file_size: 230525
  relation: main_file
file_date_updated: 2020-07-14T12:45:00Z
has_accepted_license: '1'
intvolume: '        20'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
publication: Electronic Communications in Probability
publication_status: published
publisher: Institute of Mathematical Statistics
publist_id: '5660'
pubrep_id: '494'
quality_controlled: '1'
scopus_import: 1
status: public
title: From large deviations to Wasserstein gradient flows in multiple dimensions
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 20
year: '2015'
...
---
_id: '1519'
abstract:
- lang: eng
  text: Evolutionary biologists have an array of powerful theoretical techniques that
    can accurately predict changes in the genetic composition of populations. Changes
    in gene frequencies and genetic associations between loci can be tracked as they
    respond to a wide variety of evolutionary forces. However, it is often less clear
    how to decompose these various forces into components that accurately reflect
    the underlying biology. Here, we present several issues that arise in the definition
    and interpretation of selection and selection coefficients, focusing on insights
    gained through the examination of selection coefficients in multilocus notation.
    Using this notation, we discuss how its flexibility-which allows different biological
    units to be identified as targets of selection-is reflected in the interpretation
    of the coefficients that the notation generates. In many situations, it can be
    difficult to agree on whether loci can be considered to be under &quot;direct&quot;
    versus &quot;indirect&quot; selection, or to quantify this selection. We present
    arguments for what the terms direct and indirect selection might best encompass,
    considering a range of issues, from viability and sexual selection to kin selection.
    We show how multilocus notation can discriminate between direct and indirect selection,
    and describe when it can do so.
author:
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
- first_name: Maria
  full_name: Servedio, Maria
  last_name: Servedio
citation:
  ama: Barton NH, Servedio M. The interpretation of selection coefficients. <i>Evolution</i>.
    2015;69(5):1101-1112. doi:<a href="https://doi.org/10.1111/evo.12641">10.1111/evo.12641</a>
  apa: Barton, N. H., &#38; Servedio, M. (2015). The interpretation of selection coefficients.
    <i>Evolution</i>. Wiley. <a href="https://doi.org/10.1111/evo.12641">https://doi.org/10.1111/evo.12641</a>
  chicago: Barton, Nicholas H, and Maria Servedio. “The Interpretation of Selection
    Coefficients.” <i>Evolution</i>. Wiley, 2015. <a href="https://doi.org/10.1111/evo.12641">https://doi.org/10.1111/evo.12641</a>.
  ieee: N. H. Barton and M. Servedio, “The interpretation of selection coefficients,”
    <i>Evolution</i>, vol. 69, no. 5. Wiley, pp. 1101–1112, 2015.
  ista: Barton NH, Servedio M. 2015. The interpretation of selection coefficients.
    Evolution. 69(5), 1101–1112.
  mla: Barton, Nicholas H., and Maria Servedio. “The Interpretation of Selection Coefficients.”
    <i>Evolution</i>, vol. 69, no. 5, Wiley, 2015, pp. 1101–12, doi:<a href="https://doi.org/10.1111/evo.12641">10.1111/evo.12641</a>.
  short: N.H. Barton, M. Servedio, Evolution 69 (2015) 1101–1112.
date_created: 2018-12-11T11:52:29Z
date_published: 2015-03-19T00:00:00Z
date_updated: 2021-01-12T06:51:20Z
day: '19'
ddc:
- '570'
department:
- _id: NiBa
doi: 10.1111/evo.12641
ec_funded: 1
file:
- access_level: open_access
  checksum: fd8d23f476bc194419929b72ca265c02
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:10:34Z
  date_updated: 2020-07-14T12:45:00Z
  file_id: '4822'
  file_name: IST-2016-560-v1+1_Interpreting_ML_coefficients_11.2.15_App.pdf
  file_size: 188872
  relation: main_file
- access_level: open_access
  checksum: b774911e70044641d556e258efcb52ef
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:10:35Z
  date_updated: 2020-07-14T12:45:00Z
  file_id: '4823'
  file_name: IST-2016-560-v1+2_Interpreting_ML_coefficients_11.2.15_mainText.pdf
  file_size: 577415
  relation: main_file
file_date_updated: 2020-07-14T12:45:00Z
has_accepted_license: '1'
intvolume: '        69'
issue: '5'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Submitted Version
page: 1101 - 1112
project:
- _id: 25B07788-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '250152'
  name: Limits to selection in biology and in evolutionary computation
publication: Evolution
publication_status: published
publisher: Wiley
publist_id: '5656'
pubrep_id: '560'
quality_controlled: '1'
scopus_import: 1
status: public
title: The interpretation of selection coefficients
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 69
year: '2015'
...
---
_id: '1520'
abstract:
- lang: eng
  text: Creating mechanical automata that can walk in stable and pleasing manners
    is a challenging task that requires both skill and expertise. We propose to use
    computational design to offset the technical difficulties of this process. A simple
    drag-and-drop interface allows casual users to create personalized walking toys
    from a library of pre-defined template mechanisms. Provided with this input, our
    method leverages physical simulation and evolutionary optimization to refine the
    mechanical designs such that the resulting toys are able to walk. The optimization
    process is guided by an intuitive set of objectives that measure the quality of
    the walking motions. We demonstrate our approach on a set of simulated mechanical
    toys with different numbers of legs and various distinct gaits. Two fabricated
    prototypes showcase the feasibility of our designs.
author:
- first_name: Gaurav
  full_name: Bharaj, Gaurav
  last_name: Bharaj
- first_name: Stelian
  full_name: Coros, Stelian
  last_name: Coros
- first_name: Bernhard
  full_name: Thomaszewski, Bernhard
  last_name: Thomaszewski
- first_name: James
  full_name: Tompkin, James
  last_name: Tompkin
- first_name: Bernd
  full_name: Bickel, Bernd
  id: 49876194-F248-11E8-B48F-1D18A9856A87
  last_name: Bickel
  orcid: 0000-0001-6511-9385
- first_name: Hanspeter
  full_name: Pfister, Hanspeter
  last_name: Pfister
citation:
  ama: 'Bharaj G, Coros S, Thomaszewski B, Tompkin J, Bickel B, Pfister H. Computational
    design of walking automata. In: ACM; 2015:93-100. doi:<a href="https://doi.org/10.1145/2786784.2786803">10.1145/2786784.2786803</a>'
  apa: 'Bharaj, G., Coros, S., Thomaszewski, B., Tompkin, J., Bickel, B., &#38; Pfister,
    H. (2015). Computational design of walking automata (pp. 93–100). Presented at
    the SCA: ACM SIGGRAPH/Eurographics Symposium on Computer animation, Los Angeles,
    CA, United States: ACM. <a href="https://doi.org/10.1145/2786784.2786803">https://doi.org/10.1145/2786784.2786803</a>'
  chicago: Bharaj, Gaurav, Stelian Coros, Bernhard Thomaszewski, James Tompkin, Bernd
    Bickel, and Hanspeter Pfister. “Computational Design of Walking Automata,” 93–100.
    ACM, 2015. <a href="https://doi.org/10.1145/2786784.2786803">https://doi.org/10.1145/2786784.2786803</a>.
  ieee: 'G. Bharaj, S. Coros, B. Thomaszewski, J. Tompkin, B. Bickel, and H. Pfister,
    “Computational design of walking automata,” presented at the SCA: ACM SIGGRAPH/Eurographics
    Symposium on Computer animation, Los Angeles, CA, United States, 2015, pp. 93–100.'
  ista: 'Bharaj G, Coros S, Thomaszewski B, Tompkin J, Bickel B, Pfister H. 2015.
    Computational design of walking automata. SCA: ACM SIGGRAPH/Eurographics Symposium
    on Computer animation, 93–100.'
  mla: Bharaj, Gaurav, et al. <i>Computational Design of Walking Automata</i>. ACM,
    2015, pp. 93–100, doi:<a href="https://doi.org/10.1145/2786784.2786803">10.1145/2786784.2786803</a>.
  short: G. Bharaj, S. Coros, B. Thomaszewski, J. Tompkin, B. Bickel, H. Pfister,
    in:, ACM, 2015, pp. 93–100.
conference:
  end_date: 2015-08-09
  location: Los Angeles, CA, United States
  name: 'SCA: ACM SIGGRAPH/Eurographics Symposium on Computer animation'
  start_date: 2015-08-07
date_created: 2018-12-11T11:52:30Z
date_published: 2015-08-01T00:00:00Z
date_updated: 2021-01-12T06:51:21Z
day: '01'
department:
- _id: BeBi
doi: 10.1145/2786784.2786803
language:
- iso: eng
month: '08'
oa_version: None
page: 93 - 100
publication_identifier:
  isbn:
  - 978-1-4503-3496-9
publication_status: published
publisher: ACM
publist_id: '5655'
quality_controlled: '1'
scopus_import: 1
status: public
title: Computational design of walking automata
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2015'
...
---
_id: '1530'
abstract:
- lang: eng
  text: In growing cells, protein synthesis and cell growth are typically not synchronous,
    and, thus, protein concentrations vary over the cell division cycle. We have developed
    a theoretical description of genetic regulatory systems in bacteria that explicitly
    considers the cell division cycle to investigate its impact on gene expression.
    We calculate the cell-to-cell variations arising from cells being at different
    stages in the division cycle for unregulated genes and for basic regulatory mechanisms.
    These variations contribute to the extrinsic noise observed in single-cell experiments,
    and are most significant for proteins with short lifetimes. Negative autoregulation
    buffers against variation of protein concentration over the division cycle, but
    the effect is found to be relatively weak. Stronger buffering is achieved by an
    increased protein lifetime. Positive autoregulation can strongly amplify such
    variation if the parameters are set to values that lead to resonance-like behaviour.
    For cooperative positive autoregulation, the concentration variation over the
    division cycle diminishes the parameter region of bistability and modulates the
    switching times between the two stable states. The same effects are seen for a
    two-gene mutual-repression toggle switch. By contrast, an oscillatory circuit,
    the repressilator, is only weakly affected by the division cycle.
article_number: '066003'
author:
- first_name: Veronika
  full_name: Bierbaum, Veronika
  id: 3FD04378-F248-11E8-B48F-1D18A9856A87
  last_name: Bierbaum
- first_name: Stefan
  full_name: Klumpp, Stefan
  last_name: Klumpp
citation:
  ama: Bierbaum V, Klumpp S. Impact of the cell division cycle on gene circuits. <i>Physical
    Biology</i>. 2015;12(6). doi:<a href="https://doi.org/10.1088/1478-3975/12/6/066003">10.1088/1478-3975/12/6/066003</a>
  apa: Bierbaum, V., &#38; Klumpp, S. (2015). Impact of the cell division cycle on
    gene circuits. <i>Physical Biology</i>. IOP Publishing Ltd. <a href="https://doi.org/10.1088/1478-3975/12/6/066003">https://doi.org/10.1088/1478-3975/12/6/066003</a>
  chicago: Bierbaum, Veronika, and Stefan Klumpp. “Impact of the Cell Division Cycle
    on Gene Circuits.” <i>Physical Biology</i>. IOP Publishing Ltd., 2015. <a href="https://doi.org/10.1088/1478-3975/12/6/066003">https://doi.org/10.1088/1478-3975/12/6/066003</a>.
  ieee: V. Bierbaum and S. Klumpp, “Impact of the cell division cycle on gene circuits,”
    <i>Physical Biology</i>, vol. 12, no. 6. IOP Publishing Ltd., 2015.
  ista: Bierbaum V, Klumpp S. 2015. Impact of the cell division cycle on gene circuits.
    Physical Biology. 12(6), 066003.
  mla: Bierbaum, Veronika, and Stefan Klumpp. “Impact of the Cell Division Cycle on
    Gene Circuits.” <i>Physical Biology</i>, vol. 12, no. 6, 066003, IOP Publishing
    Ltd., 2015, doi:<a href="https://doi.org/10.1088/1478-3975/12/6/066003">10.1088/1478-3975/12/6/066003</a>.
  short: V. Bierbaum, S. Klumpp, Physical Biology 12 (2015).
date_created: 2018-12-11T11:52:33Z
date_published: 2015-09-25T00:00:00Z
date_updated: 2021-01-12T06:51:25Z
day: '25'
department:
- _id: MiSi
doi: 10.1088/1478-3975/12/6/066003
intvolume: '        12'
issue: '6'
language:
- iso: eng
month: '09'
oa_version: None
publication: Physical Biology
publication_status: published
publisher: IOP Publishing Ltd.
publist_id: '5641'
quality_controlled: '1'
scopus_import: 1
status: public
title: Impact of the cell division cycle on gene circuits
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 12
year: '2015'
...
---
_id: '1531'
abstract:
- lang: eng
  text: The Heat Kernel Signature (HKS) is a scalar quantity which is derived from
    the heat kernel of a given shape. Due to its robustness, isometry invariance,
    and multiscale nature, it has been successfully applied in many geometric applications.
    From a more general point of view, the HKS can be considered as a descriptor of
    the metric of a Riemannian manifold. Given a symmetric positive definite tensor
    field we may interpret it as the metric of some Riemannian manifold and thereby
    apply the HKS to visualize and analyze the given tensor data. In this paper, we
    propose a generalization of this approach that enables the treatment of indefinite
    tensor fields, like the stress tensor, by interpreting them as a generator of
    a positive definite tensor field. To investigate the usefulness of this approach
    we consider the stress tensor from the two-point-load model example and from a
    mechanical work piece.
alternative_title:
- Mathematics and Visualization
article_processing_charge: No
author:
- first_name: Valentin
  full_name: Zobel, Valentin
  last_name: Zobel
- first_name: Jan
  full_name: Reininghaus, Jan
  id: 4505473A-F248-11E8-B48F-1D18A9856A87
  last_name: Reininghaus
- first_name: Ingrid
  full_name: Hotz, Ingrid
  last_name: Hotz
citation:
  ama: 'Zobel V, Reininghaus J, Hotz I. Visualizing symmetric indefinite 2D tensor
    fields using The Heat Kernel Signature. In: Hotz I, Schultz T, eds. <i>Visualization
    and Processing of Higher Order Descriptors for Multi-Valued Data</i>. Vol 40.
    1st ed. Springer; 2015:257-267. doi:<a href="https://doi.org/10.1007/978-3-319-15090-1_13">10.1007/978-3-319-15090-1_13</a>'
  apa: Zobel, V., Reininghaus, J., &#38; Hotz, I. (2015). Visualizing symmetric indefinite
    2D tensor fields using The Heat Kernel Signature. In I. Hotz &#38; T. Schultz
    (Eds.), <i>Visualization and Processing of Higher Order Descriptors for Multi-Valued
    Data</i> (1st ed., Vol. 40, pp. 257–267). Springer. <a href="https://doi.org/10.1007/978-3-319-15090-1_13">https://doi.org/10.1007/978-3-319-15090-1_13</a>
  chicago: Zobel, Valentin, Jan Reininghaus, and Ingrid Hotz. “Visualizing Symmetric
    Indefinite 2D Tensor Fields Using The Heat Kernel Signature.” In <i>Visualization
    and Processing of Higher Order Descriptors for Multi-Valued Data</i>, edited by
    Ingrid Hotz and Thomas Schultz, 1st ed., 40:257–67. Springer, 2015. <a href="https://doi.org/10.1007/978-3-319-15090-1_13">https://doi.org/10.1007/978-3-319-15090-1_13</a>.
  ieee: V. Zobel, J. Reininghaus, and I. Hotz, “Visualizing symmetric indefinite 2D
    tensor fields using The Heat Kernel Signature,” in <i>Visualization and Processing
    of Higher Order Descriptors for Multi-Valued Data</i>, 1st ed., vol. 40, I. Hotz
    and T. Schultz, Eds. Springer, 2015, pp. 257–267.
  ista: 'Zobel V, Reininghaus J, Hotz I. 2015.Visualizing symmetric indefinite 2D
    tensor fields using The Heat Kernel Signature. In: Visualization and Processing
    of Higher Order Descriptors for Multi-Valued Data. Mathematics and Visualization,
    vol. 40, 257–267.'
  mla: Zobel, Valentin, et al. “Visualizing Symmetric Indefinite 2D Tensor Fields
    Using The Heat Kernel Signature.” <i>Visualization and Processing of Higher Order
    Descriptors for Multi-Valued Data</i>, edited by Ingrid Hotz and Thomas Schultz,
    1st ed., vol. 40, Springer, 2015, pp. 257–67, doi:<a href="https://doi.org/10.1007/978-3-319-15090-1_13">10.1007/978-3-319-15090-1_13</a>.
  short: V. Zobel, J. Reininghaus, I. Hotz, in:, I. Hotz, T. Schultz (Eds.), Visualization
    and Processing of Higher Order Descriptors for Multi-Valued Data, 1st ed., Springer,
    2015, pp. 257–267.
date_created: 2018-12-11T11:52:33Z
date_published: 2015-01-01T00:00:00Z
date_updated: 2022-06-10T09:50:14Z
day: '01'
department:
- _id: HeEd
doi: 10.1007/978-3-319-15090-1_13
edition: '1'
editor:
- first_name: Ingrid
  full_name: Hotz, Ingrid
  last_name: Hotz
- first_name: Thomas
  full_name: Schultz, Thomas
  last_name: Schultz
intvolume: '        40'
language:
- iso: eng
month: '01'
oa_version: None
page: 257 - 267
publication: Visualization and Processing of Higher Order Descriptors for Multi-Valued
  Data
publication_identifier:
  isbn:
  - 978-3-319-15089-5
publication_status: published
publisher: Springer
publist_id: '5640'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Visualizing symmetric indefinite 2D tensor fields using The Heat Kernel Signature
type: book_chapter
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 40
year: '2015'
...
---
_id: '1532'
abstract:
- lang: eng
  text: Ammonium is the major nitrogen source in some plant ecosystems but is toxic
    at high concentrations, especially when available as the exclusive nitrogen source.
    Ammonium stress rapidly leads to various metabolic and hormonal imbalances that
    ultimately inhibit root and shoot growth in many plant species, including Arabidopsis
    thaliana (L.) Heynh. To identify molecular and genetic factors involved in seedling
    survival with prolonged exclusive NH4+ nutrition, a transcriptomic analysis with
    microarrays was used. Substantial transcriptional differences were most pronounced
    in (NH4)2SO4-grown seedlings, compared with plants grown on KNO3 or NH4NO3. Consistent
    with previous physiological analyses, major differences in the expression modules
    of photosynthesis-related genes, an altered mitochondrial metabolism, differential
    expression of the primary NH4+ assimilation, alteration of transporter gene expression
    and crucial changes in cell wall biosynthesis were found. A major difference in
    plant hormone responses, particularly of auxin but not cytokinin, was striking.
    The activity of the DR5::GUS reporter revealed a dramatically decreased auxin
    response in (NH4)2SO4-grown primary roots. The impaired root growth on (NH4)2SO4
    was partially rescued by exogenous auxin or in specific mutants in the auxin pathway.
    The data suggest that NH4+-induced nutritional and metabolic imbalances can be
    partially overcome by elevated auxin levels.
article_processing_charge: No
article_type: original
author:
- first_name: Huaiyu
  full_name: Yang, Huaiyu
  last_name: Yang
- first_name: Jenny
  full_name: Von Der Fecht Bartenbach, Jenny
  last_name: Von Der Fecht Bartenbach
- first_name: Jirí
  full_name: Friml, Jirí
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
- first_name: Jan
  full_name: Lohmann, Jan
  last_name: Lohmann
- first_name: Benjamin
  full_name: Neuhäuser, Benjamin
  last_name: Neuhäuser
- first_name: Uwe
  full_name: Ludewig, Uwe
  last_name: Ludewig
citation:
  ama: Yang H, Von Der Fecht Bartenbach J, Friml J, Lohmann J, Neuhäuser B, Ludewig
    U. Auxin-modulated root growth inhibition in Arabidopsis thaliana seedlings with
    ammonium as the sole nitrogen source. <i>Functional Plant Biology</i>. 2015;42(3):239-251.
    doi:<a href="https://doi.org/10.1071/FP14171">10.1071/FP14171</a>
  apa: Yang, H., Von Der Fecht Bartenbach, J., Friml, J., Lohmann, J., Neuhäuser,
    B., &#38; Ludewig, U. (2015). Auxin-modulated root growth inhibition in Arabidopsis
    thaliana seedlings with ammonium as the sole nitrogen source. <i>Functional Plant
    Biology</i>. CSIRO. <a href="https://doi.org/10.1071/FP14171">https://doi.org/10.1071/FP14171</a>
  chicago: Yang, Huaiyu, Jenny Von Der Fecht Bartenbach, Jiří Friml, Jan Lohmann,
    Benjamin Neuhäuser, and Uwe Ludewig. “Auxin-Modulated Root Growth Inhibition in
    Arabidopsis Thaliana Seedlings with Ammonium as the Sole Nitrogen Source.” <i>Functional
    Plant Biology</i>. CSIRO, 2015. <a href="https://doi.org/10.1071/FP14171">https://doi.org/10.1071/FP14171</a>.
  ieee: H. Yang, J. Von Der Fecht Bartenbach, J. Friml, J. Lohmann, B. Neuhäuser,
    and U. Ludewig, “Auxin-modulated root growth inhibition in Arabidopsis thaliana
    seedlings with ammonium as the sole nitrogen source,” <i>Functional Plant Biology</i>,
    vol. 42, no. 3. CSIRO, pp. 239–251, 2015.
  ista: Yang H, Von Der Fecht Bartenbach J, Friml J, Lohmann J, Neuhäuser B, Ludewig
    U. 2015. Auxin-modulated root growth inhibition in Arabidopsis thaliana seedlings
    with ammonium as the sole nitrogen source. Functional Plant Biology. 42(3), 239–251.
  mla: Yang, Huaiyu, et al. “Auxin-Modulated Root Growth Inhibition in Arabidopsis
    Thaliana Seedlings with Ammonium as the Sole Nitrogen Source.” <i>Functional Plant
    Biology</i>, vol. 42, no. 3, CSIRO, 2015, pp. 239–51, doi:<a href="https://doi.org/10.1071/FP14171">10.1071/FP14171</a>.
  short: H. Yang, J. Von Der Fecht Bartenbach, J. Friml, J. Lohmann, B. Neuhäuser,
    U. Ludewig, Functional Plant Biology 42 (2015) 239–251.
date_created: 2018-12-11T11:52:34Z
date_published: 2015-03-01T00:00:00Z
date_updated: 2022-05-24T09:02:24Z
day: '01'
department:
- _id: JiFr
doi: 10.1071/FP14171
external_id:
  pmid:
  - '32480670'
intvolume: '        42'
issue: '3'
language:
- iso: eng
month: '03'
oa_version: None
page: 239 - 251
pmid: 1
publication: Functional Plant Biology
publication_identifier:
  issn:
  - 1445-4408
publication_status: published
publisher: CSIRO
publist_id: '5639'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Auxin-modulated root growth inhibition in Arabidopsis thaliana seedlings with
  ammonium as the sole nitrogen source
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 42
year: '2015'
...
---
_id: '1533'
abstract:
- lang: eng
  text: This paper addresses the problem of semantic segmentation, where the possible
    class labels are from a predefined set. We exploit top-down guidance, i.e., the
    coarse localization of the objects and their class labels provided by object detectors.
    For each detected bounding box, figure-ground segmentation is performed and the
    final result is achieved by merging the figure-ground segmentations. The main
    idea of the proposed approach, which is presented in our preliminary work, is
    to reformulate the figure-ground segmentation problem as sparse reconstruction
    pursuing the object mask in a nonparametric manner. The latent segmentation mask
    should be coherent subject to sparse error caused by intra-category diversity;
    thus, the object mask is inferred by making use of sparse representations over
    the training set. To handle local spatial deformations, local patch-level masks
    are also considered and inferred by sparse representations over the spatially
    nearby patches. The sparse reconstruction coefficients and the latent mask are
    alternately optimized by applying the Lasso algorithm and the accelerated proximal
    gradient method. The proposed formulation results in a convex optimization problem;
    thus, the global optimal solution is achieved. In this paper, we provide theoretical
    analysis of the convergence and optimality. We also give an extended numerical
    analysis of the proposed algorithm and a comprehensive comparison with the related
    semantic segmentation methods on the challenging PASCAL visual object class object
    segmentation datasets and the Weizmann horse dataset. The experimental results
    demonstrate that the proposed algorithm achieves a competitive performance when
    compared with the state of the arts.
author:
- first_name: Wei
  full_name: Xia, Wei
  last_name: Xia
- first_name: Csaba
  full_name: Domokos, Csaba
  id: 492DACF8-F248-11E8-B48F-1D18A9856A87
  last_name: Domokos
- first_name: Junjun
  full_name: Xiong, Junjun
  last_name: Xiong
- first_name: Loongfah
  full_name: Cheong, Loongfah
  last_name: Cheong
- first_name: Shuicheng
  full_name: Yan, Shuicheng
  last_name: Yan
citation:
  ama: Xia W, Domokos C, Xiong J, Cheong L, Yan S. Segmentation over detection via
    optimal sparse reconstructions. <i>IEEE Transactions on Circuits and Systems for
    Video Technology</i>. 2015;25(8):1295-1308. doi:<a href="https://doi.org/10.1109/TCSVT.2014.2379972">10.1109/TCSVT.2014.2379972</a>
  apa: Xia, W., Domokos, C., Xiong, J., Cheong, L., &#38; Yan, S. (2015). Segmentation
    over detection via optimal sparse reconstructions. <i>IEEE Transactions on Circuits
    and Systems for Video Technology</i>. IEEE. <a href="https://doi.org/10.1109/TCSVT.2014.2379972">https://doi.org/10.1109/TCSVT.2014.2379972</a>
  chicago: Xia, Wei, Csaba Domokos, Junjun Xiong, Loongfah Cheong, and Shuicheng Yan.
    “Segmentation over Detection via Optimal Sparse Reconstructions.” <i>IEEE Transactions
    on Circuits and Systems for Video Technology</i>. IEEE, 2015. <a href="https://doi.org/10.1109/TCSVT.2014.2379972">https://doi.org/10.1109/TCSVT.2014.2379972</a>.
  ieee: W. Xia, C. Domokos, J. Xiong, L. Cheong, and S. Yan, “Segmentation over detection
    via optimal sparse reconstructions,” <i>IEEE Transactions on Circuits and Systems
    for Video Technology</i>, vol. 25, no. 8. IEEE, pp. 1295–1308, 2015.
  ista: Xia W, Domokos C, Xiong J, Cheong L, Yan S. 2015. Segmentation over detection
    via optimal sparse reconstructions. IEEE Transactions on Circuits and Systems
    for Video Technology. 25(8), 1295–1308.
  mla: Xia, Wei, et al. “Segmentation over Detection via Optimal Sparse Reconstructions.”
    <i>IEEE Transactions on Circuits and Systems for Video Technology</i>, vol. 25,
    no. 8, IEEE, 2015, pp. 1295–308, doi:<a href="https://doi.org/10.1109/TCSVT.2014.2379972">10.1109/TCSVT.2014.2379972</a>.
  short: W. Xia, C. Domokos, J. Xiong, L. Cheong, S. Yan, IEEE Transactions on Circuits
    and Systems for Video Technology 25 (2015) 1295–1308.
date_created: 2018-12-11T11:52:34Z
date_published: 2015-08-01T00:00:00Z
date_updated: 2021-01-12T06:51:26Z
day: '01'
department:
- _id: ChLa
doi: 10.1109/TCSVT.2014.2379972
intvolume: '        25'
issue: '8'
language:
- iso: eng
month: '08'
oa_version: None
page: 1295 - 1308
publication: IEEE Transactions on Circuits and Systems for Video Technology
publication_status: published
publisher: IEEE
publist_id: '5638'
quality_controlled: '1'
scopus_import: 1
status: public
title: Segmentation over detection via optimal sparse reconstructions
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 25
year: '2015'
...
---
_id: '1534'
abstract:
- lang: eng
  text: PIN proteins are auxin export carriers that direct intercellular auxin flow
    and in turn regulate many aspects of plant growth and development including responses
    to environmental changes. The Arabidopsis R2R3-MYB transcription factor FOUR LIPS
    (FLP) and its paralogue MYB88 regulate terminal divisions during stomatal development,
    as well as female reproductive development and stress responses. Here we show
    that FLP and MYB88 act redundantly but differentially in regulating the transcription
    of PIN3 and PIN7 in gravity-sensing cells of primary and lateral roots. On the
    one hand, FLP is involved in responses to gravity stimulation in primary roots,
    whereas on the other, FLP and MYB88 function complementarily in establishing the
    gravitropic set-point angles of lateral roots. Our results support a model in
    which FLP and MYB88 expression specifically determines the temporal-spatial patterns
    of PIN3 and PIN7 transcription that are closely associated with their preferential
    functions during root responses to gravity.
article_number: '8822'
author:
- first_name: Hongzhe
  full_name: Wang, Hongzhe
  last_name: Wang
- first_name: Kezhen
  full_name: Yang, Kezhen
  last_name: Yang
- first_name: Junjie
  full_name: Zou, Junjie
  last_name: Zou
- first_name: Lingling
  full_name: Zhu, Lingling
  last_name: Zhu
- first_name: Zidian
  full_name: Xie, Zidian
  last_name: Xie
- first_name: Miyoterao
  full_name: Morita, Miyoterao
  last_name: Morita
- first_name: Masao
  full_name: Tasaka, Masao
  last_name: Tasaka
- first_name: Jirí
  full_name: Friml, Jirí
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
- first_name: Erich
  full_name: Grotewold, Erich
  last_name: Grotewold
- first_name: Tom
  full_name: Beeckman, Tom
  last_name: Beeckman
- first_name: Steffen
  full_name: Vanneste, Steffen
  last_name: Vanneste
- first_name: Fred
  full_name: Sack, Fred
  last_name: Sack
- first_name: Jie
  full_name: Le, Jie
  last_name: Le
citation:
  ama: Wang H, Yang K, Zou J, et al. Transcriptional regulation of PIN genes by FOUR
    LIPS and MYB88 during Arabidopsis root gravitropism. <i>Nature Communications</i>.
    2015;6. doi:<a href="https://doi.org/10.1038/ncomms9822">10.1038/ncomms9822</a>
  apa: Wang, H., Yang, K., Zou, J., Zhu, L., Xie, Z., Morita, M., … Le, J. (2015).
    Transcriptional regulation of PIN genes by FOUR LIPS and MYB88 during Arabidopsis
    root gravitropism. <i>Nature Communications</i>. Nature Publishing Group. <a href="https://doi.org/10.1038/ncomms9822">https://doi.org/10.1038/ncomms9822</a>
  chicago: Wang, Hongzhe, Kezhen Yang, Junjie Zou, Lingling Zhu, Zidian Xie, Miyoterao
    Morita, Masao Tasaka, et al. “Transcriptional Regulation of PIN Genes by FOUR
    LIPS and MYB88 during Arabidopsis Root Gravitropism.” <i>Nature Communications</i>.
    Nature Publishing Group, 2015. <a href="https://doi.org/10.1038/ncomms9822">https://doi.org/10.1038/ncomms9822</a>.
  ieee: H. Wang <i>et al.</i>, “Transcriptional regulation of PIN genes by FOUR LIPS
    and MYB88 during Arabidopsis root gravitropism,” <i>Nature Communications</i>,
    vol. 6. Nature Publishing Group, 2015.
  ista: Wang H, Yang K, Zou J, Zhu L, Xie Z, Morita M, Tasaka M, Friml J, Grotewold
    E, Beeckman T, Vanneste S, Sack F, Le J. 2015. Transcriptional regulation of PIN
    genes by FOUR LIPS and MYB88 during Arabidopsis root gravitropism. Nature Communications.
    6, 8822.
  mla: Wang, Hongzhe, et al. “Transcriptional Regulation of PIN Genes by FOUR LIPS
    and MYB88 during Arabidopsis Root Gravitropism.” <i>Nature Communications</i>,
    vol. 6, 8822, Nature Publishing Group, 2015, doi:<a href="https://doi.org/10.1038/ncomms9822">10.1038/ncomms9822</a>.
  short: H. Wang, K. Yang, J. Zou, L. Zhu, Z. Xie, M. Morita, M. Tasaka, J. Friml,
    E. Grotewold, T. Beeckman, S. Vanneste, F. Sack, J. Le, Nature Communications
    6 (2015).
date_created: 2018-12-11T11:52:34Z
date_published: 2015-11-18T00:00:00Z
date_updated: 2021-01-12T06:51:26Z
day: '18'
ddc:
- '570'
department:
- _id: JiFr
doi: 10.1038/ncomms9822
ec_funded: 1
file:
- access_level: open_access
  checksum: 3c06735fc7cd7e482ca830cbd26001bf
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:17:07Z
  date_updated: 2020-07-14T12:45:01Z
  file_id: '5259'
  file_name: IST-2016-485-v1+1_ncomms9822.pdf
  file_size: 1852268
  relation: main_file
file_date_updated: 2020-07-14T12:45:01Z
has_accepted_license: '1'
intvolume: '         6'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
project:
- _id: 25716A02-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '282300'
  name: Polarity and subcellular dynamics in plants
publication: Nature Communications
publication_status: published
publisher: Nature Publishing Group
publist_id: '5637'
pubrep_id: '485'
quality_controlled: '1'
scopus_import: 1
status: public
title: Transcriptional regulation of PIN genes by FOUR LIPS and MYB88 during Arabidopsis
  root gravitropism
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 6
year: '2015'
...
---
_id: '1535'
abstract:
- lang: eng
  text: Neuronal and neuroendocrine L-type calcium channels (Cav1.2, Cav1.3) open
    readily at relatively low membrane potentials and allow Ca2+ to enter the cells
    near resting potentials. In this way, Cav1.2 and Cav1.3 shape the action potential
    waveform, contribute to gene expression, synaptic plasticity, neuronal differentiation,
    hormone secretion and pacemaker activity. In the chromaffin cells (CCs) of the
    adrenal medulla, Cav1.3 is highly expressed and is shown to support most of the
    pacemaking current that sustains action potential (AP) firings and part of the
    catecholamine secretion. Cav1.3 forms Ca2+-nanodomains with the fast inactivating
    BK channels and drives the resting SK currents. These latter set the inter-spike
    interval duration between consecutive spikes during spontaneous firing and the
    rate of spike adaptation during sustained depolarizations. Cav1.3 plays also a
    primary role in the switch from “tonic” to “burst” firing that occurs in mouse
    CCs when either the availability of voltage-gated Na channels (Nav) is reduced
    or the β2 subunit featuring the fast inactivating BK channels is deleted. Here,
    we discuss the functional role of these “neuronlike” firing modes in CCs and how
    Cav1.3 contributes to them. The open issue is to understand how these novel firing
    patterns are adapted to regulate the quantity of circulating catecholamines during
    resting condition or in response to acute and chronic stress.
acknowledgement: This work was supported by the Italian MIUR (PRIN 2010/2011 project
  2010JFYFY2) and the University of Torino.
article_processing_charge: No
article_type: original
author:
- first_name: David H
  full_name: Vandael, David H
  id: 3AE48E0A-F248-11E8-B48F-1D18A9856A87
  last_name: Vandael
  orcid: 0000-0001-7577-1676
- first_name: Andrea
  full_name: Marcantoni, Andrea
  last_name: Marcantoni
- first_name: Emilio
  full_name: Carbone, Emilio
  last_name: Carbone
citation:
  ama: Vandael DH, Marcantoni A, Carbone E. Cav1.3 channels as key regulators of neuron-like
    firings and catecholamine release in chromaffin cells. <i>Current Molecular Pharmacology</i>.
    2015;8(2):149-161. doi:<a href="https://doi.org/10.2174/1874467208666150507105443">10.2174/1874467208666150507105443</a>
  apa: Vandael, D. H., Marcantoni, A., &#38; Carbone, E. (2015). Cav1.3 channels as
    key regulators of neuron-like firings and catecholamine release in chromaffin
    cells. <i>Current Molecular Pharmacology</i>. Bentham Science Publishers. <a href="https://doi.org/10.2174/1874467208666150507105443">https://doi.org/10.2174/1874467208666150507105443</a>
  chicago: Vandael, David H, Andrea Marcantoni, and Emilio Carbone. “Cav1.3 Channels
    as Key Regulators of Neuron-like Firings and Catecholamine Release in Chromaffin
    Cells.” <i>Current Molecular Pharmacology</i>. Bentham Science Publishers, 2015.
    <a href="https://doi.org/10.2174/1874467208666150507105443">https://doi.org/10.2174/1874467208666150507105443</a>.
  ieee: D. H. Vandael, A. Marcantoni, and E. Carbone, “Cav1.3 channels as key regulators
    of neuron-like firings and catecholamine release in chromaffin cells,” <i>Current
    Molecular Pharmacology</i>, vol. 8, no. 2. Bentham Science Publishers, pp. 149–161,
    2015.
  ista: Vandael DH, Marcantoni A, Carbone E. 2015. Cav1.3 channels as key regulators
    of neuron-like firings and catecholamine release in chromaffin cells. Current
    Molecular Pharmacology. 8(2), 149–161.
  mla: Vandael, David H., et al. “Cav1.3 Channels as Key Regulators of Neuron-like
    Firings and Catecholamine Release in Chromaffin Cells.” <i>Current Molecular Pharmacology</i>,
    vol. 8, no. 2, Bentham Science Publishers, 2015, pp. 149–61, doi:<a href="https://doi.org/10.2174/1874467208666150507105443">10.2174/1874467208666150507105443</a>.
  short: D.H. Vandael, A. Marcantoni, E. Carbone, Current Molecular Pharmacology 8
    (2015) 149–161.
date_created: 2018-12-11T11:52:35Z
date_published: 2015-10-01T00:00:00Z
date_updated: 2021-01-12T06:51:26Z
day: '01'
department:
- _id: PeJo
doi: 10.2174/1874467208666150507105443
external_id:
  pmid:
  - '25966692'
intvolume: '         8'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384372/
month: '10'
oa: 1
oa_version: Submitted Version
page: 149 - 161
pmid: 1
publication: Current Molecular Pharmacology
publication_status: published
publisher: Bentham Science Publishers
publist_id: '5636'
quality_controlled: '1'
scopus_import: 1
status: public
title: Cav1.3 channels as key regulators of neuron-like firings and catecholamine
  release in chromaffin cells
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 8
year: '2015'
...
---
_id: '1536'
abstract:
- lang: eng
  text: Strigolactones, first discovered as germination stimulants for parasitic weeds
    [1], are carotenoid-derived phytohormones that play major roles in inhibiting
    lateral bud outgrowth and promoting plant-mycorrhizal symbiosis [2-4]. Furthermore,
    strigolactones are involved in the regulation of lateral and adventitious root
    development, root cell division [5, 6], secondary growth [7], and leaf senescence
    [8]. Recently, we discovered the strigolactone transporter Petunia axillaris PLEIOTROPIC
    DRUG RESISTANCE 1 (PaPDR1), which is required for efficient mycorrhizal colonization
    and inhibition of lateral bud outgrowth [9]. However, how strigolactones are transported
    through the plant remained unknown. Here we show that PaPDR1 exhibits a cell-type-specific
    asymmetric localization in different root tissues. In root tips, PaPDR1 is co-expressed
    with the strigolactone biosynthetic gene DAD1 (CCD8), and it is localized at the
    apical membrane of root hypodermal cells, presumably mediating the shootward transport
    of strigolactone. Above the root tip, in the hypodermal passage cells that form
    gates for the entry of mycorrhizal fungi, PaPDR1 is present in the outer-lateral
    membrane, compatible with its postulated function as strigolactone exporter from
    root to soil. Transport studies are in line with our localization studies since
    (1) a papdr1 mutant displays impaired transport of strigolactones out of the root
    tip to the shoot as well as into the rhizosphere and (2) DAD1 expression and PIN1/PIN2
    levels change in plants deregulated for PDR1 expression, suggestive of variations
    in endogenous strigolactone contents. In conclusion, our results indicate that
    the polar localizations of PaPDR1 mediate directional shootward strigolactone
    transport as well as localized exudation into the soil.
acknowledgement: "This work was funded by a grant of the Swiss National Foundation
  to E.M.\r\nWe thank Dr. José María Mateos (University of Zurich) for providing us
  with the vibratome, Prof. Dolf Weijers (Wageningen University, the Netherlands)
  for shipping us his set of ligation-independent cloning vectors, Prof. Bruno Humbel
  (University of Lausanne) for suggestions on GFP-PDR1 detection, and Dr. Undine Krügel
  (University of Zurich) and Prof. Michal Jasinski (Polish Academy of Science) for
  hints on protein quantification."
author:
- first_name: Joëlle
  full_name: Sasse, Joëlle
  last_name: Sasse
- first_name: Sibu
  full_name: Simon, Sibu
  id: 4542EF9A-F248-11E8-B48F-1D18A9856A87
  last_name: Simon
  orcid: 0000-0002-1998-6741
- first_name: Christian
  full_name: Gübeli, Christian
  last_name: Gübeli
- first_name: Guowei
  full_name: Liu, Guowei
  last_name: Liu
- first_name: Xi
  full_name: Cheng, Xi
  last_name: Cheng
- first_name: Jirí
  full_name: Friml, Jirí
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
- first_name: Harro
  full_name: Bouwmeester, Harro
  last_name: Bouwmeester
- first_name: Enrico
  full_name: Martinoia, Enrico
  last_name: Martinoia
- first_name: Lorenzo
  full_name: Borghi, Lorenzo
  last_name: Borghi
citation:
  ama: Sasse J, Simon S, Gübeli C, et al. Asymmetric localizations of the ABC transporter
    PaPDR1 trace paths of directional strigolactone transport. <i>Current Biology</i>.
    2015;25(5):647-655. doi:<a href="https://doi.org/10.1016/j.cub.2015.01.015">10.1016/j.cub.2015.01.015</a>
  apa: Sasse, J., Simon, S., Gübeli, C., Liu, G., Cheng, X., Friml, J., … Borghi,
    L. (2015). Asymmetric localizations of the ABC transporter PaPDR1 trace paths
    of directional strigolactone transport. <i>Current Biology</i>. Cell Press. <a
    href="https://doi.org/10.1016/j.cub.2015.01.015">https://doi.org/10.1016/j.cub.2015.01.015</a>
  chicago: Sasse, Joëlle, Sibu Simon, Christian Gübeli, Guowei Liu, Xi Cheng, Jiří
    Friml, Harro Bouwmeester, Enrico Martinoia, and Lorenzo Borghi. “Asymmetric Localizations
    of the ABC Transporter PaPDR1 Trace Paths of Directional Strigolactone Transport.”
    <i>Current Biology</i>. Cell Press, 2015. <a href="https://doi.org/10.1016/j.cub.2015.01.015">https://doi.org/10.1016/j.cub.2015.01.015</a>.
  ieee: J. Sasse <i>et al.</i>, “Asymmetric localizations of the ABC transporter PaPDR1
    trace paths of directional strigolactone transport,” <i>Current Biology</i>, vol.
    25, no. 5. Cell Press, pp. 647–655, 2015.
  ista: Sasse J, Simon S, Gübeli C, Liu G, Cheng X, Friml J, Bouwmeester H, Martinoia
    E, Borghi L. 2015. Asymmetric localizations of the ABC transporter PaPDR1 trace
    paths of directional strigolactone transport. Current Biology. 25(5), 647–655.
  mla: Sasse, Joëlle, et al. “Asymmetric Localizations of the ABC Transporter PaPDR1
    Trace Paths of Directional Strigolactone Transport.” <i>Current Biology</i>, vol.
    25, no. 5, Cell Press, 2015, pp. 647–55, doi:<a href="https://doi.org/10.1016/j.cub.2015.01.015">10.1016/j.cub.2015.01.015</a>.
  short: J. Sasse, S. Simon, C. Gübeli, G. Liu, X. Cheng, J. Friml, H. Bouwmeester,
    E. Martinoia, L. Borghi, Current Biology 25 (2015) 647–655.
date_created: 2018-12-11T11:52:35Z
date_published: 2015-02-12T00:00:00Z
date_updated: 2021-01-12T06:51:27Z
day: '12'
department:
- _id: JiFr
doi: 10.1016/j.cub.2015.01.015
intvolume: '        25'
issue: '5'
language:
- iso: eng
month: '02'
oa_version: None
page: 647 - 655
publication: Current Biology
publication_status: published
publisher: Cell Press
publist_id: '5635'
quality_controlled: '1'
scopus_import: 1
status: public
title: Asymmetric localizations of the ABC transporter PaPDR1 trace paths of directional
  strigolactone transport
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 25
year: '2015'
...
---
_id: '1537'
abstract:
- lang: eng
  text: 3D amoeboid cell migration is central to many developmental and disease-related
    processes such as cancer metastasis. Here, we identify a unique prototypic amoeboid
    cell migration mode in early zebrafish embryos, termed stable-bleb migration.
    Stable-bleb cells display an invariant polarized balloon-like shape with exceptional
    migration speed and persistence. Progenitor cells can be reversibly transformed
    into stable-bleb cells irrespective of their primary fate and motile characteristics
    by increasing myosin II activity through biochemical or mechanical stimuli. Using
    a combination of theory and experiments, we show that, in stable-bleb cells, cortical
    contractility fluctuations trigger a stochastic switch into amoeboid motility,
    and a positive feedback between cortical flows and gradients in contractility
    maintains stable-bleb cell polarization. We further show that rearward cortical
    flows drive stable-bleb cell migration in various adhesive and non-adhesive environments,
    unraveling a highly versatile amoeboid migration phenotype.
acknowledged_ssus:
- _id: SSU
acknowledgement: 'We would like to thank R. Hausschild and E. Papusheva for technical
  assistance and the service facilities at the IST Austria for continuous support.
  The caRhoA plasmid was a kind gift of T. Kudoh and A. Takesono. We thank M. Piel
  and E. Paluch for exchanging unpublished data. '
author:
- first_name: Verena
  full_name: Ruprecht, Verena
  id: 4D71A03A-F248-11E8-B48F-1D18A9856A87
  last_name: Ruprecht
  orcid: 0000-0003-4088-8633
- first_name: Stefan
  full_name: Wieser, Stefan
  id: 355AA5A0-F248-11E8-B48F-1D18A9856A87
  last_name: Wieser
  orcid: 0000-0002-2670-2217
- first_name: Andrew
  full_name: Callan Jones, Andrew
  last_name: Callan Jones
- first_name: Michael
  full_name: Smutny, Michael
  id: 3FE6E4E8-F248-11E8-B48F-1D18A9856A87
  last_name: Smutny
  orcid: 0000-0002-5920-9090
- first_name: Hitoshi
  full_name: Morita, Hitoshi
  id: 4C6E54C6-F248-11E8-B48F-1D18A9856A87
  last_name: Morita
- first_name: Keisuke
  full_name: Sako, Keisuke
  id: 3BED66BE-F248-11E8-B48F-1D18A9856A87
  last_name: Sako
  orcid: 0000-0002-6453-8075
- first_name: Vanessa
  full_name: Barone, Vanessa
  id: 419EECCC-F248-11E8-B48F-1D18A9856A87
  last_name: Barone
  orcid: 0000-0003-2676-3367
- first_name: Monika
  full_name: Ritsch Marte, Monika
  last_name: Ritsch Marte
- first_name: Michael K
  full_name: Sixt, Michael K
  id: 41E9FBEA-F248-11E8-B48F-1D18A9856A87
  last_name: Sixt
  orcid: 0000-0002-6620-9179
- first_name: Raphaël
  full_name: Voituriez, Raphaël
  last_name: Voituriez
- first_name: Carl-Philipp J
  full_name: Heisenberg, Carl-Philipp J
  id: 39427864-F248-11E8-B48F-1D18A9856A87
  last_name: Heisenberg
  orcid: 0000-0002-0912-4566
citation:
  ama: Ruprecht V, Wieser S, Callan Jones A, et al. Cortical contractility triggers
    a stochastic switch to fast amoeboid cell motility. <i>Cell</i>. 2015;160(4):673-685.
    doi:<a href="https://doi.org/10.1016/j.cell.2015.01.008">10.1016/j.cell.2015.01.008</a>
  apa: Ruprecht, V., Wieser, S., Callan Jones, A., Smutny, M., Morita, H., Sako, K.,
    … Heisenberg, C.-P. J. (2015). Cortical contractility triggers a stochastic switch
    to fast amoeboid cell motility. <i>Cell</i>. Cell Press. <a href="https://doi.org/10.1016/j.cell.2015.01.008">https://doi.org/10.1016/j.cell.2015.01.008</a>
  chicago: Ruprecht, Verena, Stefan Wieser, Andrew Callan Jones, Michael Smutny, Hitoshi
    Morita, Keisuke Sako, Vanessa Barone, et al. “Cortical Contractility Triggers
    a Stochastic Switch to Fast Amoeboid Cell Motility.” <i>Cell</i>. Cell Press,
    2015. <a href="https://doi.org/10.1016/j.cell.2015.01.008">https://doi.org/10.1016/j.cell.2015.01.008</a>.
  ieee: V. Ruprecht <i>et al.</i>, “Cortical contractility triggers a stochastic switch
    to fast amoeboid cell motility,” <i>Cell</i>, vol. 160, no. 4. Cell Press, pp.
    673–685, 2015.
  ista: Ruprecht V, Wieser S, Callan Jones A, Smutny M, Morita H, Sako K, Barone V,
    Ritsch Marte M, Sixt MK, Voituriez R, Heisenberg C-PJ. 2015. Cortical contractility
    triggers a stochastic switch to fast amoeboid cell motility. Cell. 160(4), 673–685.
  mla: Ruprecht, Verena, et al. “Cortical Contractility Triggers a Stochastic Switch
    to Fast Amoeboid Cell Motility.” <i>Cell</i>, vol. 160, no. 4, Cell Press, 2015,
    pp. 673–85, doi:<a href="https://doi.org/10.1016/j.cell.2015.01.008">10.1016/j.cell.2015.01.008</a>.
  short: V. Ruprecht, S. Wieser, A. Callan Jones, M. Smutny, H. Morita, K. Sako, V.
    Barone, M. Ritsch Marte, M.K. Sixt, R. Voituriez, C.-P.J. Heisenberg, Cell 160
    (2015) 673–685.
date_created: 2018-12-11T11:52:35Z
date_published: 2015-02-12T00:00:00Z
date_updated: 2023-09-07T12:05:08Z
day: '12'
ddc:
- '570'
department:
- _id: CaHe
- _id: MiSi
doi: 10.1016/j.cell.2015.01.008
file:
- access_level: open_access
  checksum: 228d3edf40627d897b3875088a0ac51f
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:13:21Z
  date_updated: 2020-07-14T12:45:01Z
  file_id: '5003'
  file_name: IST-2016-484-v1+1_1-s2.0-S0092867415000094-main.pdf
  file_size: 4362653
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file_date_updated: 2020-07-14T12:45:01Z
has_accepted_license: '1'
intvolume: '       160'
issue: '4'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
page: 673 - 685
project:
- _id: 2529486C-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: T 560-B17
  name: Cell- and Tissue Mechanics in Zebrafish Germ Layer Formation
- _id: 2527D5CC-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: I 812-B12
  name: Cell Cortex and Germ Layer Formation in Zebrafish Gastrulation
publication: Cell
publication_status: published
publisher: Cell Press
publist_id: '5634'
pubrep_id: '484'
quality_controlled: '1'
related_material:
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    relation: dissertation_contains
    status: public
scopus_import: 1
status: public
title: Cortical contractility triggers a stochastic switch to fast amoeboid cell motility
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 160
year: '2015'
...
