---
_id: '5809'
abstract:
- lang: eng
  text: A discrete spherical circle is a topologically well-connected 3D circle in
    the integer space, which belongs to a discrete sphere as well as a discrete plane.
    It is one of the most important 3D geometric primitives, but has not possibly
    yet been studied up to its merit. This paper is a maiden exposition of some of
    its elementary properties, which indicates a sense of its profound theoretical
    prospects in the framework of digital geometry. We have shown how different types
    of discretization can lead to forbidden and admissible classes, when one attempts
    to define the discretization of a spherical circle in terms of intersection between
    a discrete sphere and a discrete plane. Several fundamental theoretical results
    have been presented, the algorithm for construction of discrete spherical circles
    has been discussed, and some test results have been furnished to demonstrate its
    practicality and usefulness.
article_processing_charge: No
author:
- first_name: Ranita
  full_name: Biswas, Ranita
  id: 3C2B033E-F248-11E8-B48F-1D18A9856A87
  last_name: Biswas
  orcid: 0000-0002-5372-7890
- first_name: Partha
  full_name: Bhowmick, Partha
  last_name: Bhowmick
- first_name: Valentin E.
  full_name: Brimkov, Valentin E.
  last_name: Brimkov
citation:
  ama: 'Biswas R, Bhowmick P, Brimkov VE. On the connectivity and smoothness of discrete
    spherical circles. In: <i>Combinatorial Image Analysis</i>. Vol 9448. Cham: Springer
    Nature; 2016:86-100. doi:<a href="https://doi.org/10.1007/978-3-319-26145-4_7">10.1007/978-3-319-26145-4_7</a>'
  apa: 'Biswas, R., Bhowmick, P., &#38; Brimkov, V. E. (2016). On the connectivity
    and smoothness of discrete spherical circles. In <i>Combinatorial image analysis</i>
    (Vol. 9448, pp. 86–100). Cham: Springer Nature. <a href="https://doi.org/10.1007/978-3-319-26145-4_7">https://doi.org/10.1007/978-3-319-26145-4_7</a>'
  chicago: 'Biswas, Ranita, Partha Bhowmick, and Valentin E. Brimkov. “On the Connectivity
    and Smoothness of Discrete Spherical Circles.” In <i>Combinatorial Image Analysis</i>,
    9448:86–100. Cham: Springer Nature, 2016. <a href="https://doi.org/10.1007/978-3-319-26145-4_7">https://doi.org/10.1007/978-3-319-26145-4_7</a>.'
  ieee: 'R. Biswas, P. Bhowmick, and V. E. Brimkov, “On the connectivity and smoothness
    of discrete spherical circles,” in <i>Combinatorial image analysis</i>, vol. 9448,
    Cham: Springer Nature, 2016, pp. 86–100.'
  ista: 'Biswas R, Bhowmick P, Brimkov VE. 2016.On the connectivity and smoothness
    of discrete spherical circles. In: Combinatorial image analysis. vol. 9448, 86–100.'
  mla: Biswas, Ranita, et al. “On the Connectivity and Smoothness of Discrete Spherical
    Circles.” <i>Combinatorial Image Analysis</i>, vol. 9448, Springer Nature, 2016,
    pp. 86–100, doi:<a href="https://doi.org/10.1007/978-3-319-26145-4_7">10.1007/978-3-319-26145-4_7</a>.
  short: R. Biswas, P. Bhowmick, V.E. Brimkov, in:, Combinatorial Image Analysis,
    Springer Nature, Cham, 2016, pp. 86–100.
conference:
  end_date: 2015-11-27
  location: Kolkata, India
  name: 'IWCIA: International Workshop on Combinatorial Image Analysis'
  start_date: 2015-11-24
date_created: 2019-01-08T20:45:19Z
date_published: 2016-01-06T00:00:00Z
date_updated: 2022-01-28T08:13:03Z
day: '06'
department:
- _id: HeEd
doi: 10.1007/978-3-319-26145-4_7
extern: '1'
intvolume: '      9448'
language:
- iso: eng
month: '01'
oa_version: None
page: 86-100
place: Cham
publication: Combinatorial image analysis
publication_identifier:
  eisbn:
  - 978-3-319-26145-4
  eissn:
  - 1611-3349
  isbn:
  - 978-3-319-26144-7
  issn:
  - 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: On the connectivity and smoothness of discrete spherical circles
type: book_chapter
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 9448
year: '2016'
...
---
_id: '1431'
abstract:
- lang: eng
  text: The rare socially parasitic butterfly Maculinea alcon occurs in two forms,
    which are characteristic of hygric or xeric habitats and which exploit different
    host plants and host ants. The status of these two forms has been the subject
    of considerable controversy. Populations of the two forms are usually spatially
    distinct, but at Răscruci in Romania both forms occur on the same site (syntopically).
    We examined the genetic differentiation between the two forms using eight microsatellite
    markers, and compared with a nearby hygric site, Şardu. Our results showed that
    while the two forms are strongly differentiated at Răscruci, it is the xeric form
    there that is most similar to the hygric form at Şardu, and Bayesian clustering
    algorithms suggest that these two populations have exchanged genes relatively
    recently. We found strong evidence for population substructuring, caused by high
    within host ant nest relatedness, indicating very limited dispersal of most ovipositing
    females, but not association with particular host ant species. Our results are
    consistent with the results of larger scale phylogeographic studies that suggest
    that the two forms represent local ecotypes specialising on different host plants,
    each with a distinct flowering phenology, providing a temporal rather than spatial
    barrier to gene flow.
article_number: '1865'
author:
- first_name: András
  full_name: Tartally, András
  last_name: Tartally
- first_name: Andreas
  full_name: Kelager, Andreas
  last_name: Kelager
- first_name: Matthias
  full_name: Fürst, Matthias
  id: 393B1196-F248-11E8-B48F-1D18A9856A87
  last_name: Fürst
  orcid: 0000-0002-3712-925X
- first_name: David
  full_name: Nash, David
  last_name: Nash
citation:
  ama: Tartally A, Kelager A, Fürst M, Nash D. Host plant use drives genetic differentiation
    in syntopic populations of Maculinea alcon. <i>PeerJ</i>. 2016;2016(3). doi:<a
    href="https://doi.org/10.7717/peerj.1865">10.7717/peerj.1865</a>
  apa: Tartally, A., Kelager, A., Fürst, M., &#38; Nash, D. (2016). Host plant use
    drives genetic differentiation in syntopic populations of Maculinea alcon. <i>PeerJ</i>.
    PeerJ. <a href="https://doi.org/10.7717/peerj.1865">https://doi.org/10.7717/peerj.1865</a>
  chicago: Tartally, András, Andreas Kelager, Matthias Fürst, and David Nash. “Host
    Plant Use Drives Genetic Differentiation in Syntopic Populations of Maculinea
    Alcon.” <i>PeerJ</i>. PeerJ, 2016. <a href="https://doi.org/10.7717/peerj.1865">https://doi.org/10.7717/peerj.1865</a>.
  ieee: A. Tartally, A. Kelager, M. Fürst, and D. Nash, “Host plant use drives genetic
    differentiation in syntopic populations of Maculinea alcon,” <i>PeerJ</i>, vol.
    2016, no. 3. PeerJ, 2016.
  ista: Tartally A, Kelager A, Fürst M, Nash D. 2016. Host plant use drives genetic
    differentiation in syntopic populations of Maculinea alcon. PeerJ. 2016(3), 1865.
  mla: Tartally, András, et al. “Host Plant Use Drives Genetic Differentiation in
    Syntopic Populations of Maculinea Alcon.” <i>PeerJ</i>, vol. 2016, no. 3, 1865,
    PeerJ, 2016, doi:<a href="https://doi.org/10.7717/peerj.1865">10.7717/peerj.1865</a>.
  short: A. Tartally, A. Kelager, M. Fürst, D. Nash, PeerJ 2016 (2016).
date_created: 2018-12-11T11:51:59Z
date_published: 2016-01-01T00:00:00Z
date_updated: 2021-01-12T06:50:41Z
day: '01'
ddc:
- '570'
department:
- _id: SyCr
doi: 10.7717/peerj.1865
file:
- access_level: open_access
  checksum: c27d898598a1e3d7f629607a309254e1
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:17:19Z
  date_updated: 2020-07-14T12:44:53Z
  file_id: '5272'
  file_name: IST-2016-584-v1+1_peerj-1865.pdf
  file_size: 1216360
  relation: main_file
file_date_updated: 2020-07-14T12:44:53Z
has_accepted_license: '1'
intvolume: '      2016'
issue: '3'
language:
- iso: eng
license: https://creativecommons.org/licenses/by/4.0/
month: '01'
oa: 1
oa_version: Published Version
publication: PeerJ
publication_status: published
publisher: PeerJ
publist_id: '5767'
pubrep_id: '584'
quality_controlled: '1'
scopus_import: 1
status: public
title: Host plant use drives genetic differentiation in syntopic populations of Maculinea
  alcon
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 2016
year: '2016'
...
---
_id: '1432'
abstract:
- lang: eng
  text: CA3–CA3 recurrent excitatory synapses are thought to play a key role in memory
    storage and pattern completion. Whether the plasticity properties of these synapses
    are consistent with their proposed network functions remains unclear. Here, we
    examine the properties of spike timing-dependent plasticity (STDP) at CA3–CA3
    synapses. Low-frequency pairing of excitatory postsynaptic potentials (EPSPs)
    and action potentials (APs) induces long-term potentiation (LTP), independent
    of temporal order. The STDP curve is symmetric and broad (half-width ~150 ms).
    Consistent with these STDP induction properties, AP–EPSP sequences lead to supralinear
    summation of spine [Ca2+] transients. Furthermore, afterdepolarizations (ADPs)
    following APs efficiently propagate into dendrites of CA3 pyramidal neurons, and
    EPSPs summate with dendritic ADPs. In autoassociative network models, storage
    and recall are more robust with symmetric than with asymmetric STDP rules. Thus,
    a specialized STDP induction rule allows reliable storage and recall of information
    in the hippocampal CA3 network.
acknowledgement: 'We thank Jozsef Csicsvari and Nelson Spruston for critically reading
  the manuscript. We also thank A. Schlögl for programming, F. Marr for technical
  assistance and E. Kramberger for manuscript editing. '
article_number: '11552'
author:
- first_name: Rajiv Kumar
  full_name: Mishra, Rajiv Kumar
  id: 46CB58F2-F248-11E8-B48F-1D18A9856A87
  last_name: Mishra
- first_name: Sooyun
  full_name: Kim, Sooyun
  id: 394AB1C8-F248-11E8-B48F-1D18A9856A87
  last_name: Kim
- first_name: José
  full_name: Guzmán, José
  id: 30CC5506-F248-11E8-B48F-1D18A9856A87
  last_name: Guzmán
  orcid: 0000-0003-2209-5242
- first_name: Peter M
  full_name: Jonas, Peter M
  id: 353C1B58-F248-11E8-B48F-1D18A9856A87
  last_name: Jonas
  orcid: 0000-0001-5001-4804
citation:
  ama: Mishra RK, Kim S, Guzmán J, Jonas PM. Symmetric spike timing-dependent plasticity
    at CA3–CA3 synapses optimizes storage and recall in autoassociative networks.
    <i>Nature Communications</i>. 2016;7. doi:<a href="https://doi.org/10.1038/ncomms11552">10.1038/ncomms11552</a>
  apa: Mishra, R. K., Kim, S., Guzmán, J., &#38; Jonas, P. M. (2016). Symmetric spike
    timing-dependent plasticity at CA3–CA3 synapses optimizes storage and recall in
    autoassociative networks. <i>Nature Communications</i>. Nature Publishing Group.
    <a href="https://doi.org/10.1038/ncomms11552">https://doi.org/10.1038/ncomms11552</a>
  chicago: Mishra, Rajiv Kumar, Sooyun Kim, José Guzmán, and Peter M Jonas. “Symmetric
    Spike Timing-Dependent Plasticity at CA3–CA3 Synapses Optimizes Storage and Recall
    in Autoassociative Networks.” <i>Nature Communications</i>. Nature Publishing
    Group, 2016. <a href="https://doi.org/10.1038/ncomms11552">https://doi.org/10.1038/ncomms11552</a>.
  ieee: R. K. Mishra, S. Kim, J. Guzmán, and P. M. Jonas, “Symmetric spike timing-dependent
    plasticity at CA3–CA3 synapses optimizes storage and recall in autoassociative
    networks,” <i>Nature Communications</i>, vol. 7. Nature Publishing Group, 2016.
  ista: Mishra RK, Kim S, Guzmán J, Jonas PM. 2016. Symmetric spike timing-dependent
    plasticity at CA3–CA3 synapses optimizes storage and recall in autoassociative
    networks. Nature Communications. 7, 11552.
  mla: Mishra, Rajiv Kumar, et al. “Symmetric Spike Timing-Dependent Plasticity at
    CA3–CA3 Synapses Optimizes Storage and Recall in Autoassociative Networks.” <i>Nature
    Communications</i>, vol. 7, 11552, Nature Publishing Group, 2016, doi:<a href="https://doi.org/10.1038/ncomms11552">10.1038/ncomms11552</a>.
  short: R.K. Mishra, S. Kim, J. Guzmán, P.M. Jonas, Nature Communications 7 (2016).
date_created: 2018-12-11T11:51:59Z
date_published: 2016-05-13T00:00:00Z
date_updated: 2023-09-07T11:55:25Z
day: '13'
ddc:
- '570'
department:
- _id: PeJo
doi: 10.1038/ncomms11552
ec_funded: 1
file:
- access_level: open_access
  checksum: 7e84d0392348c874d473b62f1042de22
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:18:33Z
  date_updated: 2020-07-14T12:44:53Z
  file_id: '5355'
  file_name: IST-2016-582-v1+1_ncomms11552.pdf
  file_size: 4510512
  relation: main_file
file_date_updated: 2020-07-14T12:44:53Z
has_accepted_license: '1'
intvolume: '         7'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
project:
- _id: 25C26B1E-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: P24909-B24
  name: Mechanisms of transmitter release at GABAergic synapses
- _id: 25C0F108-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '268548'
  name: Nanophysiology of fast-spiking, parvalbumin-expressing GABAergic interneurons
publication: Nature Communications
publication_status: published
publisher: Nature Publishing Group
publist_id: '5766'
pubrep_id: '582'
quality_controlled: '1'
related_material:
  record:
  - id: '1396'
    relation: dissertation_contains
    status: public
scopus_import: 1
status: public
title: Symmetric spike timing-dependent plasticity at CA3–CA3 synapses optimizes storage
  and recall in autoassociative networks
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 7
year: '2016'
...
---
_id: '1434'
abstract:
- lang: eng
  text: We prove that the system of subordination equations, defining the free additive
    convolution of two probability measures, is stable away from the edges of the
    support and blow-up singularities by showing that the recent smoothness condition
    of Kargin is always satisfied. As an application, we consider the local spectral
    statistics of the random matrix ensemble A+UBU⁎A+UBU⁎, where U is a Haar distributed
    random unitary or orthogonal matrix, and A and B   are deterministic matrices.
    In the bulk regime, we prove that the empirical spectral distribution of A+UBU⁎A+UBU⁎
    concentrates around the free additive convolution of the spectral distributions
    of A and B   on scales down to N−2/3N−2/3.
author:
- first_name: Zhigang
  full_name: Bao, Zhigang
  id: 442E6A6C-F248-11E8-B48F-1D18A9856A87
  last_name: Bao
  orcid: 0000-0003-3036-1475
- first_name: László
  full_name: Erdös, László
  id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
  last_name: Erdös
  orcid: 0000-0001-5366-9603
- first_name: Kevin
  full_name: Schnelli, Kevin
  id: 434AD0AE-F248-11E8-B48F-1D18A9856A87
  last_name: Schnelli
  orcid: 0000-0003-0954-3231
citation:
  ama: Bao Z, Erdös L, Schnelli K. Local stability of the free additive convolution.
    <i>Journal of Functional Analysis</i>. 2016;271(3):672-719. doi:<a href="https://doi.org/10.1016/j.jfa.2016.04.006">10.1016/j.jfa.2016.04.006</a>
  apa: Bao, Z., Erdös, L., &#38; Schnelli, K. (2016). Local stability of the free
    additive convolution. <i>Journal of Functional Analysis</i>. Academic Press. <a
    href="https://doi.org/10.1016/j.jfa.2016.04.006">https://doi.org/10.1016/j.jfa.2016.04.006</a>
  chicago: Bao, Zhigang, László Erdös, and Kevin Schnelli. “Local Stability of the
    Free Additive Convolution.” <i>Journal of Functional Analysis</i>. Academic Press,
    2016. <a href="https://doi.org/10.1016/j.jfa.2016.04.006">https://doi.org/10.1016/j.jfa.2016.04.006</a>.
  ieee: Z. Bao, L. Erdös, and K. Schnelli, “Local stability of the free additive convolution,”
    <i>Journal of Functional Analysis</i>, vol. 271, no. 3. Academic Press, pp. 672–719,
    2016.
  ista: Bao Z, Erdös L, Schnelli K. 2016. Local stability of the free additive convolution.
    Journal of Functional Analysis. 271(3), 672–719.
  mla: Bao, Zhigang, et al. “Local Stability of the Free Additive Convolution.” <i>Journal
    of Functional Analysis</i>, vol. 271, no. 3, Academic Press, 2016, pp. 672–719,
    doi:<a href="https://doi.org/10.1016/j.jfa.2016.04.006">10.1016/j.jfa.2016.04.006</a>.
  short: Z. Bao, L. Erdös, K. Schnelli, Journal of Functional Analysis 271 (2016)
    672–719.
date_created: 2018-12-11T11:52:00Z
date_published: 2016-08-01T00:00:00Z
date_updated: 2021-01-12T06:50:42Z
day: '01'
department:
- _id: LaEr
doi: 10.1016/j.jfa.2016.04.006
ec_funded: 1
intvolume: '       271'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: http://arxiv.org/abs/1508.05905
month: '08'
oa: 1
oa_version: Preprint
page: 672 - 719
project:
- _id: 258DCDE6-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '338804'
  name: Random matrices, universality and disordered quantum systems
publication: Journal of Functional Analysis
publication_status: published
publisher: Academic Press
publist_id: '5764'
quality_controlled: '1'
scopus_import: 1
status: public
title: Local stability of the free additive convolution
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 271
year: '2016'
...
---
_id: '1435'
abstract:
- lang: eng
  text: ATP released from neurons and astrocytes during neuronal activity or under
    pathophysiological circumstances is able to influence information flow in neuronal
    circuits by activation of ionotropic P2X and metabotropic P2Y receptors and subsequent
    modulation of cellular excitability, synaptic strength, and plasticity. In the
    present paper we review cellular and network effects of P2Y receptors in the brain.
    We show that P2Y receptors inhibit the release of neurotransmitters, modulate
    voltage- and ligand-gated ion channels, and differentially influence the induction
    of synaptic plasticity in the prefrontal cortex, hippocampus, and cerebellum.
    The findings discussed here may explain how P2Y1 receptor activation during brain
    injury, hypoxia, inflammation, schizophrenia, or Alzheimer's disease leads to
    an impairment of cognitive processes. Hence, it is suggested that the blockade
    of P2Y1 receptors may have therapeutic potential against cognitive disturbances
    in these states.
article_number: '1207393'
author:
- first_name: José
  full_name: Guzmán, José
  id: 30CC5506-F248-11E8-B48F-1D18A9856A87
  last_name: Guzmán
- first_name: Zoltan
  full_name: Gerevich, Zoltan
  last_name: Gerevich
citation:
  ama: 'Guzmán J, Gerevich Z. P2Y receptors in synaptic transmission and plasticity:
    Therapeutic potential in cognitive dysfunction. <i>Neural Plasticity</i>. 2016;2016.
    doi:<a href="https://doi.org/10.1155/2016/1207393">10.1155/2016/1207393</a>'
  apa: 'Guzmán, J., &#38; Gerevich, Z. (2016). P2Y receptors in synaptic transmission
    and plasticity: Therapeutic potential in cognitive dysfunction. <i>Neural Plasticity</i>.
    Hindawi Publishing Corporation. <a href="https://doi.org/10.1155/2016/1207393">https://doi.org/10.1155/2016/1207393</a>'
  chicago: 'Guzmán, José, and Zoltan Gerevich. “P2Y Receptors in Synaptic Transmission
    and Plasticity: Therapeutic Potential in Cognitive Dysfunction.” <i>Neural Plasticity</i>.
    Hindawi Publishing Corporation, 2016. <a href="https://doi.org/10.1155/2016/1207393">https://doi.org/10.1155/2016/1207393</a>.'
  ieee: 'J. Guzmán and Z. Gerevich, “P2Y receptors in synaptic transmission and plasticity:
    Therapeutic potential in cognitive dysfunction,” <i>Neural Plasticity</i>, vol.
    2016. Hindawi Publishing Corporation, 2016.'
  ista: 'Guzmán J, Gerevich Z. 2016. P2Y receptors in synaptic transmission and plasticity:
    Therapeutic potential in cognitive dysfunction. Neural Plasticity. 2016, 1207393.'
  mla: 'Guzmán, José, and Zoltan Gerevich. “P2Y Receptors in Synaptic Transmission
    and Plasticity: Therapeutic Potential in Cognitive Dysfunction.” <i>Neural Plasticity</i>,
    vol. 2016, 1207393, Hindawi Publishing Corporation, 2016, doi:<a href="https://doi.org/10.1155/2016/1207393">10.1155/2016/1207393</a>.'
  short: J. Guzmán, Z. Gerevich, Neural Plasticity 2016 (2016).
date_created: 2018-12-11T11:52:00Z
date_published: 2016-01-01T00:00:00Z
date_updated: 2021-01-12T06:50:43Z
day: '01'
ddc:
- '570'
department:
- _id: PeJo
doi: 10.1155/2016/1207393
file:
- access_level: open_access
  checksum: 8dc5c2f3d44d4775a6e7e3edb0d7a0da
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:09:17Z
  date_updated: 2020-07-14T12:44:54Z
  file_id: '4740'
  file_name: IST-2016-580-v1+1_1207393.pdf
  file_size: 1395180
  relation: main_file
file_date_updated: 2020-07-14T12:44:54Z
has_accepted_license: '1'
intvolume: '      2016'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
publication: Neural Plasticity
publication_status: published
publisher: Hindawi Publishing Corporation
publist_id: '5762'
pubrep_id: '580'
quality_controlled: '1'
scopus_import: 1
status: public
title: 'P2Y receptors in synaptic transmission and plasticity: Therapeutic potential
  in cognitive dysfunction'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 2016
year: '2016'
...
---
_id: '1436'
abstract:
- lang: eng
  text: We study the time evolution of a system of N spinless fermions in R3 which
    interact through a pair potential, e.g., the Coulomb potential. We compare the
    dynamics given by the solution to Schrödinger's equation with the time-dependent
    Hartree-Fock approximation, and we give an estimate for the accuracy of this approximation
    in terms of the kinetic energy of the system. This leads, in turn, to bounds in
    terms of the initial total energy of the system.
author:
- first_name: Volker
  full_name: Bach, Volker
  last_name: Bach
- first_name: Sébastien
  full_name: Breteaux, Sébastien
  last_name: Breteaux
- first_name: Sören P
  full_name: Petrat, Sören P
  id: 40AC02DC-F248-11E8-B48F-1D18A9856A87
  last_name: Petrat
  orcid: 0000-0002-9166-5889
- first_name: Peter
  full_name: Pickl, Peter
  last_name: Pickl
- first_name: Tim
  full_name: Tzaneteas, Tim
  last_name: Tzaneteas
citation:
  ama: Bach V, Breteaux S, Petrat SP, Pickl P, Tzaneteas T. Kinetic energy estimates
    for the accuracy of the time-dependent Hartree-Fock approximation with Coulomb
    interaction. <i>Journal de Mathématiques Pures et Appliquées</i>. 2016;105(1):1-30.
    doi:<a href="https://doi.org/10.1016/j.matpur.2015.09.003">10.1016/j.matpur.2015.09.003</a>
  apa: Bach, V., Breteaux, S., Petrat, S. P., Pickl, P., &#38; Tzaneteas, T. (2016).
    Kinetic energy estimates for the accuracy of the time-dependent Hartree-Fock approximation
    with Coulomb interaction. <i>Journal de Mathématiques Pures et Appliquées</i>.
    Elsevier. <a href="https://doi.org/10.1016/j.matpur.2015.09.003">https://doi.org/10.1016/j.matpur.2015.09.003</a>
  chicago: Bach, Volker, Sébastien Breteaux, Sören P Petrat, Peter Pickl, and Tim
    Tzaneteas. “Kinetic Energy Estimates for the Accuracy of the Time-Dependent Hartree-Fock
    Approximation with Coulomb Interaction.” <i>Journal de Mathématiques Pures et
    Appliquées</i>. Elsevier, 2016. <a href="https://doi.org/10.1016/j.matpur.2015.09.003">https://doi.org/10.1016/j.matpur.2015.09.003</a>.
  ieee: V. Bach, S. Breteaux, S. P. Petrat, P. Pickl, and T. Tzaneteas, “Kinetic energy
    estimates for the accuracy of the time-dependent Hartree-Fock approximation with
    Coulomb interaction,” <i>Journal de Mathématiques Pures et Appliquées</i>, vol.
    105, no. 1. Elsevier, pp. 1–30, 2016.
  ista: Bach V, Breteaux S, Petrat SP, Pickl P, Tzaneteas T. 2016. Kinetic energy
    estimates for the accuracy of the time-dependent Hartree-Fock approximation with
    Coulomb interaction. Journal de Mathématiques Pures et Appliquées. 105(1), 1–30.
  mla: Bach, Volker, et al. “Kinetic Energy Estimates for the Accuracy of the Time-Dependent
    Hartree-Fock Approximation with Coulomb Interaction.” <i>Journal de Mathématiques
    Pures et Appliquées</i>, vol. 105, no. 1, Elsevier, 2016, pp. 1–30, doi:<a href="https://doi.org/10.1016/j.matpur.2015.09.003">10.1016/j.matpur.2015.09.003</a>.
  short: V. Bach, S. Breteaux, S.P. Petrat, P. Pickl, T. Tzaneteas, Journal de Mathématiques
    Pures et Appliquées 105 (2016) 1–30.
date_created: 2018-12-11T11:52:00Z
date_published: 2016-01-01T00:00:00Z
date_updated: 2021-01-12T06:50:43Z
day: '01'
ddc:
- '510'
- '530'
department:
- _id: RoSe
doi: 10.1016/j.matpur.2015.09.003
ec_funded: 1
file:
- access_level: open_access
  checksum: c5afe1f6935bc7f2b546adbde1d31a35
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:10:36Z
  date_updated: 2020-07-14T12:44:54Z
  file_id: '4825'
  file_name: IST-2016-581-v1+1_1-s2.0-S0021782415001191-main.pdf
  file_size: 658491
  relation: main_file
file_date_updated: 2020-07-14T12:44:54Z
has_accepted_license: '1'
intvolume: '       105'
issue: '1'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-nd/4.0/
month: '01'
oa: 1
oa_version: Published Version
page: 1 - 30
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '291734'
  name: International IST Postdoc Fellowship Programme
publication: Journal de Mathématiques Pures et Appliquées
publication_status: published
publisher: Elsevier
publist_id: '5763'
pubrep_id: '581'
quality_controlled: '1'
scopus_import: 1
status: public
title: Kinetic energy estimates for the accuracy of the time-dependent Hartree-Fock
  approximation with Coulomb interaction
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 105
year: '2016'
...
---
_id: '1437'
abstract:
- lang: eng
  text: We study algorithmic questions for concurrent systems where the transitions
    are labeled from a complete, closed semiring, and path properties are algebraic
    with semiring operations. The algebraic path properties can model dataflow analysis
    problems, the shortest path problem, and many other natural problems that arise
    in program analysis. We consider that each component of the concurrent system
    is a graph with constant treewidth, a property satisfied by the controlflow graphs
    of most programs. We allow for multiple possible queries, which arise naturally
    in demand driven dataflow analysis. The study of multiple queries allows us to
    consider the tradeoff between the resource usage of the one-time preprocessing
    and for each individual query. The traditional approach constructs the product
    graph of all components and applies the best-known graph algorithm on the product.
    In this approach, even the answer to a single query requires the transitive closure
    (i.e., the results of all possible queries), which provides no room for tradeoff
    between preprocessing and query time. Our main contributions are algorithms that
    significantly improve the worst-case running time of the traditional approach,
    and provide various tradeoffs depending on the number of queries. For example,
    in a concurrent system of two components, the traditional approach requires hexic
    time in the worst case for answering one query as well as computing the transitive
    closure, whereas we show that with one-time preprocessing in almost cubic time,
    each subsequent query can be answered in at most linear time, and even the transitive
    closure can be computed in almost quartic time. Furthermore, we establish conditional
    optimality results showing that the worst-case running time of our algorithms
    cannot be improved without achieving major breakthroughs in graph algorithms (i.e.,
    improving the worst-case bound for the shortest path problem in general graphs).
    Preliminary experimental results show that our algorithms perform favorably on
    several benchmarks.
alternative_title:
- POPL
arxiv: 1
author:
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Amir
  full_name: Goharshady, Amir
  id: 391365CE-F248-11E8-B48F-1D18A9856A87
  last_name: Goharshady
  orcid: 0000-0003-1702-6584
- first_name: Rasmus
  full_name: Ibsen-Jensen, Rasmus
  id: 3B699956-F248-11E8-B48F-1D18A9856A87
  last_name: Ibsen-Jensen
  orcid: 0000-0003-4783-0389
- first_name: Andreas
  full_name: Pavlogiannis, Andreas
  id: 49704004-F248-11E8-B48F-1D18A9856A87
  last_name: Pavlogiannis
  orcid: 0000-0002-8943-0722
citation:
  ama: 'Chatterjee K, Goharshady AK, Ibsen-Jensen R, Pavlogiannis A. Algorithms for
    algebraic path properties in concurrent systems of constant treewidth components.
    In: Vol 20-22. ACM; 2016:733-747. doi:<a href="https://doi.org/10.1145/2837614.2837624">10.1145/2837614.2837624</a>'
  apa: 'Chatterjee, K., Goharshady, A. K., Ibsen-Jensen, R., &#38; Pavlogiannis, A.
    (2016). Algorithms for algebraic path properties in concurrent systems of constant
    treewidth components (Vol. 20–22, pp. 733–747). Presented at the POPL: Principles
    of Programming Languages, St. Petersburg, FL, USA: ACM. <a href="https://doi.org/10.1145/2837614.2837624">https://doi.org/10.1145/2837614.2837624</a>'
  chicago: Chatterjee, Krishnendu, Amir Kafshdar Goharshady, Rasmus Ibsen-Jensen,
    and Andreas Pavlogiannis. “Algorithms for Algebraic Path Properties in Concurrent
    Systems of Constant Treewidth Components,” 20–22:733–47. ACM, 2016. <a href="https://doi.org/10.1145/2837614.2837624">https://doi.org/10.1145/2837614.2837624</a>.
  ieee: 'K. Chatterjee, A. K. Goharshady, R. Ibsen-Jensen, and A. Pavlogiannis, “Algorithms
    for algebraic path properties in concurrent systems of constant treewidth components,”
    presented at the POPL: Principles of Programming Languages, St. Petersburg, FL,
    USA, 2016, vol. 20–22, pp. 733–747.'
  ista: 'Chatterjee K, Goharshady AK, Ibsen-Jensen R, Pavlogiannis A. 2016. Algorithms
    for algebraic path properties in concurrent systems of constant treewidth components.
    POPL: Principles of Programming Languages, POPL, vol. 20–22, 733–747.'
  mla: Chatterjee, Krishnendu, et al. <i>Algorithms for Algebraic Path Properties
    in Concurrent Systems of Constant Treewidth Components</i>. Vol. 20–22, ACM, 2016,
    pp. 733–47, doi:<a href="https://doi.org/10.1145/2837614.2837624">10.1145/2837614.2837624</a>.
  short: K. Chatterjee, A.K. Goharshady, R. Ibsen-Jensen, A. Pavlogiannis, in:, ACM,
    2016, pp. 733–747.
conference:
  end_date: 2016-01-22
  location: St. Petersburg, FL, USA
  name: 'POPL: Principles of Programming Languages'
  start_date: 2016-01-20
date_created: 2018-12-11T11:52:01Z
date_published: 2016-01-11T00:00:00Z
date_updated: 2024-03-25T23:30:18Z
day: '11'
department:
- _id: KrCh
doi: 10.1145/2837614.2837624
ec_funded: 1
external_id:
  arxiv:
  - '1510.07565'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: http://arxiv.org/abs/1510.07565
month: '01'
oa: 1
oa_version: Preprint
page: 733 - 747
project:
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: S 11407_N23
  name: Rigorous Systems Engineering
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '279307'
  name: 'Quantitative Graph Games: Theory and Applications'
publication_status: published
publisher: ACM
publist_id: '5761'
quality_controlled: '1'
related_material:
  record:
  - id: '5441'
    relation: earlier_version
    status: public
  - id: '5442'
    relation: earlier_version
    status: public
  - id: '821'
    relation: dissertation_contains
    status: public
  - id: '6009'
    relation: later_version
    status: public
  - id: '8934'
    relation: dissertation_contains
    status: public
scopus_import: 1
status: public
title: Algorithms for algebraic path properties in concurrent systems of constant
  treewidth components
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 20-22
year: '2016'
...
---
_id: '1438'
abstract:
- lang: eng
  text: 'In this paper, we consider termination of probabilistic programs with real-valued
    variables. The questions concerned are: (a) qualitative ones that ask (i) whether
    the program terminates with probability 1 (almost-sure termination) and (ii) whether
    the expected termination time is finite (finite termination); (b) quantitative
    ones that ask (i) to approximate the expected termination time (expectation problem)
    and (ii) to compute a bound B such that the probability to terminate after B steps
    decreases exponentially (concentration problem). To solve these questions, we
    utilize the notion of ranking supermartingales which is a powerful approach for
    proving termination of probabilistic programs. In detail, we focus on algorithmic
    synthesis of linear ranking-supermartingales over affine probabilistic programs
    (APP''s) with both angelic and demonic non-determinism. An important subclass
    of APP''s is LRAPP which is defined as the class of all APP''s over which a linear
    ranking-supermartingale exists. Our main contributions are as follows. Firstly,
    we show that the membership problem of LRAPP (i) can be decided in polynomial
    time for APP''s with at most demonic non-determinism, and (ii) is NP-hard and
    in PSPACE for APP''s with angelic non-determinism; moreover, the NP-hardness result
    holds already for APP''s without probability and demonic non-determinism. Secondly,
    we show that the concentration problem over LRAPP can be solved in the same complexity
    as for the membership problem of LRAPP. Finally, we show that the expectation
    problem over LRAPP can be solved in 2EXPTIME and is PSPACE-hard even for APP''s
    without probability and non-determinism (i.e., deterministic programs). Our experimental
    results demonstrate the effectiveness of our approach to answer the qualitative
    and quantitative questions over APP''s with at most demonic non-determinism.'
acknowledgement: 'Supported by the Natural Science Foundation of China (NSFC) under
  Grant No. 61532019 '
alternative_title:
- POPL
arxiv: 1
author:
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Hongfei
  full_name: Fu, Hongfei
  id: 3AAD03D6-F248-11E8-B48F-1D18A9856A87
  last_name: Fu
- first_name: Petr
  full_name: Novotny, Petr
  id: 3CC3B868-F248-11E8-B48F-1D18A9856A87
  last_name: Novotny
- first_name: Rouzbeh
  full_name: Hasheminezhad, Rouzbeh
  last_name: Hasheminezhad
citation:
  ama: 'Chatterjee K, Fu H, Novotný P, Hasheminezhad R. Algorithmic analysis of qualitative
    and quantitative termination problems for affine probabilistic programs. In: Vol
    20-22. ACM; 2016:327-342. doi:<a href="https://doi.org/10.1145/2837614.2837639">10.1145/2837614.2837639</a>'
  apa: 'Chatterjee, K., Fu, H., Novotný, P., &#38; Hasheminezhad, R. (2016). Algorithmic
    analysis of qualitative and quantitative termination problems for affine probabilistic
    programs (Vol. 20–22, pp. 327–342). Presented at the POPL: Principles of Programming
    Languages, St. Petersburg, FL, USA: ACM. <a href="https://doi.org/10.1145/2837614.2837639">https://doi.org/10.1145/2837614.2837639</a>'
  chicago: Chatterjee, Krishnendu, Hongfei Fu, Petr Novotný, and Rouzbeh Hasheminezhad.
    “Algorithmic Analysis of Qualitative and Quantitative Termination Problems for
    Affine Probabilistic Programs,” 20–22:327–42. ACM, 2016. <a href="https://doi.org/10.1145/2837614.2837639">https://doi.org/10.1145/2837614.2837639</a>.
  ieee: 'K. Chatterjee, H. Fu, P. Novotný, and R. Hasheminezhad, “Algorithmic analysis
    of qualitative and quantitative termination problems for affine probabilistic
    programs,” presented at the POPL: Principles of Programming Languages, St. Petersburg,
    FL, USA, 2016, vol. 20–22, pp. 327–342.'
  ista: 'Chatterjee K, Fu H, Novotný P, Hasheminezhad R. 2016. Algorithmic analysis
    of qualitative and quantitative termination problems for affine probabilistic
    programs. POPL: Principles of Programming Languages, POPL, vol. 20–22, 327–342.'
  mla: Chatterjee, Krishnendu, et al. <i>Algorithmic Analysis of Qualitative and Quantitative
    Termination Problems for Affine Probabilistic Programs</i>. Vol. 20–22, ACM, 2016,
    pp. 327–42, doi:<a href="https://doi.org/10.1145/2837614.2837639">10.1145/2837614.2837639</a>.
  short: K. Chatterjee, H. Fu, P. Novotný, R. Hasheminezhad, in:, ACM, 2016, pp. 327–342.
conference:
  end_date: 2016-01-22
  location: St. Petersburg, FL, USA
  name: 'POPL: Principles of Programming Languages'
  start_date: 2016-01-20
date_created: 2018-12-11T11:52:01Z
date_published: 2016-01-11T00:00:00Z
date_updated: 2023-09-19T14:38:41Z
day: '11'
department:
- _id: KrCh
doi: 10.1145/2837614.2837639
ec_funded: 1
external_id:
  arxiv:
  - '1510.08517'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: http://arxiv.org/abs/1510.08517
month: '01'
oa: 1
oa_version: Preprint
page: 327 - 342
project:
- _id: 2584A770-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: P 23499-N23
  name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: S 11407_N23
  name: Rigorous Systems Engineering
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '279307'
  name: 'Quantitative Graph Games: Theory and Applications'
- _id: 25681D80-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '291734'
  name: International IST Postdoc Fellowship Programme
publication_status: published
publisher: ACM
publist_id: '5760'
quality_controlled: '1'
related_material:
  record:
  - id: '5993'
    relation: later_version
    status: public
scopus_import: 1
status: public
title: Algorithmic analysis of qualitative and quantitative termination problems for
  affine probabilistic programs
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 20-22
year: '2016'
...
---
_id: '1439'
abstract:
- lang: eng
  text: Fault-tolerant distributed algorithms play an important role in many critical/high-availability
    applications. These algorithms are notoriously difficult to implement correctly,
    due to asynchronous communication and the occurrence of faults, such as the network
    dropping messages or computers crashing. We introduce PSYNC, a domain specific
    language based on the Heard-Of model, which views asynchronous faulty systems
    as synchronous ones with an adversarial environment that simulates asynchrony
    and faults by dropping messages. We define a runtime system for PSYNC that efficiently
    executes on asynchronous networks. We formalize the relation between the runtime
    system and PSYNC in terms of observational refinement. The high-level lockstep
    abstraction introduced by PSYNC simplifies the design and implementation of fault-tolerant
    distributed algorithms and enables automated formal verification. We have implemented
    an embedding of PSYNC in the SCALA programming language with a runtime system
    for asynchronous networks. We show the applicability of PSYNC by implementing
    several important fault-tolerant distributed algorithms and we compare the implementation
    of consensus algorithms in PSYNC against implementations in other languages in
    terms of code size, runtime efficiency, and verification.
acknowledgement: 'Damien Zufferey was supported by DARPA (Grants FA8650-11-C-7192
  and FA8650-15-C-7564) and NSF (Grant CCF-1138967). '
alternative_title:
- ACM SIGPLAN Notices
author:
- first_name: Cezara
  full_name: Dragoi, Cezara
  id: 2B2B5ED0-F248-11E8-B48F-1D18A9856A87
  last_name: Dragoi
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000−0002−2985−7724
- first_name: Damien
  full_name: Zufferey, Damien
  id: 4397AC76-F248-11E8-B48F-1D18A9856A87
  last_name: Zufferey
  orcid: 0000-0002-3197-8736
citation:
  ama: 'Dragoi C, Henzinger TA, Zufferey D. PSYNC: A partially synchronous language
    for fault-tolerant distributed algorithms. In: Vol 20-22. ACM; 2016:400-415. doi:<a
    href="https://doi.org/10.1145/2837614.2837650">10.1145/2837614.2837650</a>'
  apa: 'Dragoi, C., Henzinger, T. A., &#38; Zufferey, D. (2016). PSYNC: A partially
    synchronous language for fault-tolerant distributed algorithms (Vol. 20–22, pp.
    400–415). Presented at the POPL: Principles of Programming Languages, St. Petersburg,
    FL, USA: ACM. <a href="https://doi.org/10.1145/2837614.2837650">https://doi.org/10.1145/2837614.2837650</a>'
  chicago: 'Dragoi, Cezara, Thomas A Henzinger, and Damien Zufferey. “PSYNC: A Partially
    Synchronous Language for Fault-Tolerant Distributed Algorithms,” 20–22:400–415.
    ACM, 2016. <a href="https://doi.org/10.1145/2837614.2837650">https://doi.org/10.1145/2837614.2837650</a>.'
  ieee: 'C. Dragoi, T. A. Henzinger, and D. Zufferey, “PSYNC: A partially synchronous
    language for fault-tolerant distributed algorithms,” presented at the POPL: Principles
    of Programming Languages, St. Petersburg, FL, USA, 2016, vol. 20–22, pp. 400–415.'
  ista: 'Dragoi C, Henzinger TA, Zufferey D. 2016. PSYNC: A partially synchronous
    language for fault-tolerant distributed algorithms. POPL: Principles of Programming
    Languages, ACM SIGPLAN Notices, vol. 20–22, 400–415.'
  mla: 'Dragoi, Cezara, et al. <i>PSYNC: A Partially Synchronous Language for Fault-Tolerant
    Distributed Algorithms</i>. Vol. 20–22, ACM, 2016, pp. 400–15, doi:<a href="https://doi.org/10.1145/2837614.2837650">10.1145/2837614.2837650</a>.'
  short: C. Dragoi, T.A. Henzinger, D. Zufferey, in:, ACM, 2016, pp. 400–415.
conference:
  end_date: 2016-01-22
  location: St. Petersburg, FL, USA
  name: 'POPL: Principles of Programming Languages'
  start_date: 2016-01-20
date_created: 2018-12-11T11:52:01Z
date_published: 2016-01-11T00:00:00Z
date_updated: 2021-01-12T06:50:45Z
day: '11'
department:
- _id: ToHe
doi: 10.1145/2837614.2837650
ec_funded: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://hal.inria.fr/hal-01251199/
month: '01'
oa: 1
oa_version: Preprint
page: 400 - 415
project:
- _id: 25EE3708-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '267989'
  name: Quantitative Reactive Modeling
- _id: 25F42A32-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: Z211
  name: The Wittgenstein Prize
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: S 11407_N23
  name: Rigorous Systems Engineering
publication_status: published
publisher: ACM
publist_id: '5759'
quality_controlled: '1'
scopus_import: 1
status: public
title: 'PSYNC: A partially synchronous language for fault-tolerant distributed algorithms'
type: conference
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 20-22
year: '2016'
...
---
_id: '1440'
acknowledgement: The author thanks Banerjee et al. (2016) for providing coordinates
  prior to public release and apologizes to colleagues whose work was not cited or
  discussed due to the limited space available. The author is supported by grants
  from EU FP7 (CIG-303564), HFSP (RGY0084_2012), and FWF (W1232).
author:
- first_name: Harald L
  full_name: Janovjak, Harald L
  id: 33BA6C30-F248-11E8-B48F-1D18A9856A87
  last_name: Janovjak
  orcid: 0000-0002-8023-9315
citation:
  ama: 'Janovjak HL. Light at the end of the protein: Crystal structure of a C-terminal
    light-sensing domain. <i>Structure</i>. 2016;24(2):213-215. doi:<a href="https://doi.org/10.1016/j.str.2016.01.002">10.1016/j.str.2016.01.002</a>'
  apa: 'Janovjak, H. L. (2016). Light at the end of the protein: Crystal structure
    of a C-terminal light-sensing domain. <i>Structure</i>. Cell Press. <a href="https://doi.org/10.1016/j.str.2016.01.002">https://doi.org/10.1016/j.str.2016.01.002</a>'
  chicago: 'Janovjak, Harald L. “Light at the End of the Protein: Crystal Structure
    of a C-Terminal Light-Sensing Domain.” <i>Structure</i>. Cell Press, 2016. <a
    href="https://doi.org/10.1016/j.str.2016.01.002">https://doi.org/10.1016/j.str.2016.01.002</a>.'
  ieee: 'H. L. Janovjak, “Light at the end of the protein: Crystal structure of a
    C-terminal light-sensing domain,” <i>Structure</i>, vol. 24, no. 2. Cell Press,
    pp. 213–215, 2016.'
  ista: 'Janovjak HL. 2016. Light at the end of the protein: Crystal structure of
    a C-terminal light-sensing domain. Structure. 24(2), 213–215.'
  mla: 'Janovjak, Harald L. “Light at the End of the Protein: Crystal Structure of
    a C-Terminal Light-Sensing Domain.” <i>Structure</i>, vol. 24, no. 2, Cell Press,
    2016, pp. 213–15, doi:<a href="https://doi.org/10.1016/j.str.2016.01.002">10.1016/j.str.2016.01.002</a>.'
  short: H.L. Janovjak, Structure 24 (2016) 213–215.
date_created: 2018-12-11T11:52:02Z
date_published: 2016-02-02T00:00:00Z
date_updated: 2021-01-12T06:50:46Z
day: '02'
department:
- _id: HaJa
doi: 10.1016/j.str.2016.01.002
ec_funded: 1
intvolume: '        24'
issue: '2'
language:
- iso: eng
month: '02'
oa_version: None
page: 213 - 215
project:
- _id: 255BFFFA-B435-11E9-9278-68D0E5697425
  grant_number: RGY0084/2012
  name: In situ real-time imaging of neurotransmitter signaling using designer optical
    sensors (HFSP Young Investigator)
- _id: 25548C20-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '303564'
  name: Microbial Ion Channels for Synthetic Neurobiology
- _id: 255A6082-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: W1232-B24
  name: Molecular Drug Targets
publication: Structure
publication_status: published
publisher: Cell Press
publist_id: '5756'
quality_controlled: '1'
scopus_import: 1
status: public
title: 'Light at the end of the protein: Crystal structure of a C-terminal light-sensing
  domain'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 24
year: '2016'
...
---
_id: '1441'
abstract:
- lang: eng
  text: 'Optogenetics and photopharmacology enable the spatio-temporal control of
    cell and animal behavior by light. Although red light offers deep-tissue penetration
    and minimal phototoxicity, very few red-light-sensitive optogenetic methods are
    currently available. We have now developed a red-light-induced homodimerization
    domain. We first showed that an optimized sensory domain of the cyanobacterial
    phytochrome 1 can be expressed robustly and without cytotoxicity in human cells.
    We then applied this domain to induce the dimerization of two receptor tyrosine
    kinases—the fibroblast growth factor receptor 1 and the neurotrophin receptor
    trkB. This new optogenetic method was then used to activate the MAPK/ERK pathway
    non-invasively in mammalian tissue and in multicolor cell-signaling experiments.
    The light-controlled dimerizer and red-light-activated receptor tyrosine kinases
    will prove useful to regulate a variety of cellular processes with light. Go deep
    with red: The sensory domain (S) of the cyanobacterial phytochrome 1 (CPH1) was
    repurposed to induce the homodimerization of proteins in living cells by red light.
    By using this domain, light-activated protein kinases were engineered that can
    be activated orthogonally from many fluorescent proteins and through mammalian
    tissue. Pr/Pfr=red-/far-red-absorbing state of CPH1.'
acknowledgement: 'A.I.-P. was supported by a Ramon Areces fellowship, and E.R. by
  the graduate program MolecularDrugTargets (Austrian Science Fund (FWF): W1232) and
  a FemTech fellowship (Austrian Research Promotion Agency: 3580812).'
author:
- first_name: Eva
  full_name: Gschaider-Reichhart, Eva
  id: 3FEE232A-F248-11E8-B48F-1D18A9856A87
  last_name: Gschaider-Reichhart
  orcid: 0000-0002-7218-7738
- first_name: Álvaro
  full_name: Inglés Prieto, Álvaro
  id: 2A9DB292-F248-11E8-B48F-1D18A9856A87
  last_name: Inglés Prieto
  orcid: 0000-0002-5409-8571
- first_name: Alexandra-Madelaine
  full_name: Tichy, Alexandra-Madelaine
  id: 29D8BB2C-F248-11E8-B48F-1D18A9856A87
  last_name: Tichy
- first_name: Catherine
  full_name: Mckenzie, Catherine
  id: 3EEDE19A-F248-11E8-B48F-1D18A9856A87
  last_name: Mckenzie
- first_name: Harald L
  full_name: Janovjak, Harald L
  id: 33BA6C30-F248-11E8-B48F-1D18A9856A87
  last_name: Janovjak
  orcid: 0000-0002-8023-9315
citation:
  ama: Gschaider-Reichhart E, Inglés Prieto Á, Tichy A-M, Mckenzie C, Janovjak HL.
    A phytochrome sensory domain permits receptor activation by red light. <i>Angewandte
    Chemie - International Edition</i>. 2016;55(21):6339-6342. doi:<a href="https://doi.org/10.1002/anie.201601736">10.1002/anie.201601736</a>
  apa: Gschaider-Reichhart, E., Inglés Prieto, Á., Tichy, A.-M., Mckenzie, C., &#38;
    Janovjak, H. L. (2016). A phytochrome sensory domain permits receptor activation
    by red light. <i>Angewandte Chemie - International Edition</i>. Wiley. <a href="https://doi.org/10.1002/anie.201601736">https://doi.org/10.1002/anie.201601736</a>
  chicago: Gschaider-Reichhart, Eva, Álvaro Inglés Prieto, Alexandra-Madelaine Tichy,
    Catherine Mckenzie, and Harald L Janovjak. “A Phytochrome Sensory Domain Permits
    Receptor Activation by Red Light.” <i>Angewandte Chemie - International Edition</i>.
    Wiley, 2016. <a href="https://doi.org/10.1002/anie.201601736">https://doi.org/10.1002/anie.201601736</a>.
  ieee: E. Gschaider-Reichhart, Á. Inglés Prieto, A.-M. Tichy, C. Mckenzie, and H.
    L. Janovjak, “A phytochrome sensory domain permits receptor activation by red
    light,” <i>Angewandte Chemie - International Edition</i>, vol. 55, no. 21. Wiley,
    pp. 6339–6342, 2016.
  ista: Gschaider-Reichhart E, Inglés Prieto Á, Tichy A-M, Mckenzie C, Janovjak HL.
    2016. A phytochrome sensory domain permits receptor activation by red light. Angewandte
    Chemie - International Edition. 55(21), 6339–6342.
  mla: Gschaider-Reichhart, Eva, et al. “A Phytochrome Sensory Domain Permits Receptor
    Activation by Red Light.” <i>Angewandte Chemie - International Edition</i>, vol.
    55, no. 21, Wiley, 2016, pp. 6339–42, doi:<a href="https://doi.org/10.1002/anie.201601736">10.1002/anie.201601736</a>.
  short: E. Gschaider-Reichhart, Á. Inglés Prieto, A.-M. Tichy, C. Mckenzie, H.L.
    Janovjak, Angewandte Chemie - International Edition 55 (2016) 6339–6342.
date_created: 2018-12-11T11:52:02Z
date_published: 2016-05-17T00:00:00Z
date_updated: 2023-09-07T12:49:08Z
day: '17'
ddc:
- '571'
- '576'
department:
- _id: HaJa
doi: 10.1002/anie.201601736
ec_funded: 1
file:
- access_level: open_access
  checksum: 26da07960e57ac4750b54179197ce57f
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:17:03Z
  date_updated: 2020-07-14T12:44:55Z
  file_id: '5255'
  file_name: IST-2017-840-v1+1_reichhart.pdf
  file_size: 1268662
  relation: main_file
file_date_updated: 2020-07-14T12:44:55Z
has_accepted_license: '1'
intvolume: '        55'
issue: '21'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Submitted Version
page: 6339 - 6342
project:
- _id: 25548C20-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '303564'
  name: Microbial Ion Channels for Synthetic Neurobiology
- _id: 255A6082-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: W1232-B24
  name: Molecular Drug Targets
publication: Angewandte Chemie - International Edition
publication_status: published
publisher: Wiley
publist_id: '5755'
pubrep_id: '840'
quality_controlled: '1'
related_material:
  record:
  - id: '418'
    relation: dissertation_contains
    status: public
scopus_import: 1
status: public
title: A phytochrome sensory domain permits receptor activation by red light
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 55
year: '2016'
...
---
_id: '1446'
abstract:
- lang: eng
  text: The accuracy of interdisciplinarity measurements is directly related to the
    quality of the underlying bibliographic data. Existing indicators of interdisciplinarity
    are not capable of reflecting the inaccuracies introduced by incorrect and incomplete
    records because correct and complete bibliographic data can rarely be obtained.
    This is the case for the Rao–Stirling index, which cannot handle references that
    are not categorized into disciplinary fields. We introduce a method that addresses
    this problem. It extends the Rao–Stirling index to acknowledge missing data by
    calculating its interval of uncertainty using computational optimization. The
    evaluation of our method indicates that the uncertainty interval is not only useful
    for estimating the inaccuracy of interdisciplinarity measurements, but it also
    delivers slightly more accurate aggregated interdisciplinarity measurements than
    the Rao–Stirling index.
article_processing_charge: No
author:
- first_name: Maria
  full_name: Calatrava Moreno, Maria
  last_name: Calatrava Moreno
- first_name: Thomas
  full_name: Auzinger, Thomas
  id: 4718F954-F248-11E8-B48F-1D18A9856A87
  last_name: Auzinger
  orcid: 0000-0002-1546-3265
- first_name: Hannes
  full_name: Werthner, Hannes
  last_name: Werthner
citation:
  ama: Calatrava Moreno M, Auzinger T, Werthner H. On the uncertainty of interdisciplinarity
    measurements due to incomplete bibliographic data. <i>Scientometrics</i>. 2016;107(1):213-232.
    doi:<a href="https://doi.org/10.1007/s11192-016-1842-4">10.1007/s11192-016-1842-4</a>
  apa: Calatrava Moreno, M., Auzinger, T., &#38; Werthner, H. (2016). On the uncertainty
    of interdisciplinarity measurements due to incomplete bibliographic data. <i>Scientometrics</i>.
    Springer. <a href="https://doi.org/10.1007/s11192-016-1842-4">https://doi.org/10.1007/s11192-016-1842-4</a>
  chicago: Calatrava Moreno, Maria, Thomas Auzinger, and Hannes Werthner. “On the
    Uncertainty of Interdisciplinarity Measurements Due to Incomplete Bibliographic
    Data.” <i>Scientometrics</i>. Springer, 2016. <a href="https://doi.org/10.1007/s11192-016-1842-4">https://doi.org/10.1007/s11192-016-1842-4</a>.
  ieee: M. Calatrava Moreno, T. Auzinger, and H. Werthner, “On the uncertainty of
    interdisciplinarity measurements due to incomplete bibliographic data,” <i>Scientometrics</i>,
    vol. 107, no. 1. Springer, pp. 213–232, 2016.
  ista: Calatrava Moreno M, Auzinger T, Werthner H. 2016. On the uncertainty of interdisciplinarity
    measurements due to incomplete bibliographic data. Scientometrics. 107(1), 213–232.
  mla: Calatrava Moreno, Maria, et al. “On the Uncertainty of Interdisciplinarity
    Measurements Due to Incomplete Bibliographic Data.” <i>Scientometrics</i>, vol.
    107, no. 1, Springer, 2016, pp. 213–32, doi:<a href="https://doi.org/10.1007/s11192-016-1842-4">10.1007/s11192-016-1842-4</a>.
  short: M. Calatrava Moreno, T. Auzinger, H. Werthner, Scientometrics 107 (2016)
    213–232.
date_created: 2018-12-11T11:52:04Z
date_published: 2016-04-01T00:00:00Z
date_updated: 2021-11-16T08:29:11Z
day: '01'
ddc:
- '000'
department:
- _id: BeBi
doi: 10.1007/s11192-016-1842-4
file:
- access_level: open_access
  checksum: 32d46268588b87d9b686492018e6a2b2
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:10:56Z
  date_updated: 2020-07-14T12:44:55Z
  file_id: '4848'
  file_name: IST-2016-530-v1+1_s11192-016-1842-4.pdf
  file_size: 806035
  relation: main_file
file_date_updated: 2020-07-14T12:44:55Z
has_accepted_license: '1'
intvolume: '       107'
issue: '1'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
page: 213 - 232
publication: Scientometrics
publication_status: published
publisher: Springer
publist_id: '5750'
pubrep_id: '530'
quality_controlled: '1'
related_material:
  link:
  - relation: erratum
    url: https://doi.org/10.1007/s11192-016-1902-9
scopus_import: '1'
status: public
title: On the uncertainty of interdisciplinarity measurements due to incomplete bibliographic
  data
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 107
year: '2016'
...
---
_id: '1448'
abstract:
- lang: eng
  text: We develop a new and systematic method for proving entropic Ricci curvature
    lower bounds for Markov chains on discrete sets. Using different methods, such
    bounds have recently been obtained in several examples (e.g., 1-dimensional birth
    and death chains, product chains, Bernoulli–Laplace models, and random transposition
    models). However, a general method to obtain discrete Ricci bounds had been lacking.
    Our method covers all of the examples above. In addition we obtain new Ricci curvature
    bounds for zero-range processes on the complete graph. The method is inspired
    by recent work of Caputo, Dai Pra and Posta on discrete functional inequalities.
acknowledgement: "Supported by the German Research Foundation through the Collaborative
  Research Center 1060\r\nThe Mathematics of Emergent Effects and the Hausdorff Center
  for Mathematics. Part of this work has been done while M. Fathi visited J. Maas
  at the University of Bonn in July 2014.We would like to thank the referees for their
  careful reading of the manuscript. "
author:
- first_name: Max
  full_name: Fathi, Max
  last_name: Fathi
- first_name: Jan
  full_name: Maas, Jan
  id: 4C5696CE-F248-11E8-B48F-1D18A9856A87
  last_name: Maas
  orcid: 0000-0002-0845-1338
citation:
  ama: Fathi M, Maas J. Entropic Ricci curvature bounds for discrete interacting systems.
    <i>The Annals of Applied Probability</i>. 2016;26(3):1774-1806. doi:<a href="https://doi.org/10.1214/15-AAP1133">10.1214/15-AAP1133</a>
  apa: Fathi, M., &#38; Maas, J. (2016). Entropic Ricci curvature bounds for discrete
    interacting systems. <i>The Annals of Applied Probability</i>. Institute of Mathematical
    Statistics. <a href="https://doi.org/10.1214/15-AAP1133">https://doi.org/10.1214/15-AAP1133</a>
  chicago: Fathi, Max, and Jan Maas. “Entropic Ricci Curvature Bounds for Discrete
    Interacting Systems.” <i>The Annals of Applied Probability</i>. Institute of Mathematical
    Statistics, 2016. <a href="https://doi.org/10.1214/15-AAP1133">https://doi.org/10.1214/15-AAP1133</a>.
  ieee: M. Fathi and J. Maas, “Entropic Ricci curvature bounds for discrete interacting
    systems,” <i>The Annals of Applied Probability</i>, vol. 26, no. 3. Institute
    of Mathematical Statistics, pp. 1774–1806, 2016.
  ista: Fathi M, Maas J. 2016. Entropic Ricci curvature bounds for discrete interacting
    systems. The Annals of Applied Probability. 26(3), 1774–1806.
  mla: Fathi, Max, and Jan Maas. “Entropic Ricci Curvature Bounds for Discrete Interacting
    Systems.” <i>The Annals of Applied Probability</i>, vol. 26, no. 3, Institute
    of Mathematical Statistics, 2016, pp. 1774–806, doi:<a href="https://doi.org/10.1214/15-AAP1133">10.1214/15-AAP1133</a>.
  short: M. Fathi, J. Maas, The Annals of Applied Probability 26 (2016) 1774–1806.
date_created: 2018-12-11T11:52:05Z
date_published: 2016-06-01T00:00:00Z
date_updated: 2021-01-12T06:50:49Z
day: '01'
department:
- _id: JaMa
doi: 10.1214/15-AAP1133
intvolume: '        26'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: http://arxiv.org/abs/1501.00562
month: '06'
oa: 1
oa_version: Preprint
page: 1774 - 1806
publication: The Annals of Applied Probability
publication_status: published
publisher: Institute of Mathematical Statistics
publist_id: '5748'
quality_controlled: '1'
scopus_import: 1
status: public
title: Entropic Ricci curvature bounds for discrete interacting systems
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 26
year: '2016'
...
---
_id: '1475'
abstract:
- lang: eng
  text: The actin cytoskeleton plays important roles in the formation and internalization
    of endocytic vesicles. In yeast, endocytic vesicles move towards early endosomes
    along actin cables, however, the molecular machinery regulating interaction between
    endocytic vesicles and actin cables is poorly understood. The Eps15-like protein
    Pan1p plays a key role in actin-mediated endocytosis and is negatively regulated
    by Ark1 and Prk1 kinases. Here we show that pan1 mutated to prevent phosphorylation
    at all 18 threonines, pan1-18TA, displayed almost the same endocytic defect as
    ark1Δ prk1Δ cells, and contained abnormal actin concentrations including several
    endocytic compartments. Early endosomes were highly localized in the actin concentrations
    and displayed movement along actin cables. The dephosphorylated form of Pan1p
    also caused stable associations between endocytic vesicles and actin cables, and
    between endocytic vesicles and endosomes. Thus Pan1 phosphorylation is part of
    a novel mechanism that regulates endocytic compartment interactions with each
    other and with actin cables.
article_number: e10276
author:
- first_name: Junko
  full_name: Toshima, Junko
  last_name: Toshima
- first_name: Eri
  full_name: Furuya, Eri
  last_name: Furuya
- first_name: Makoto
  full_name: Nagano, Makoto
  last_name: Nagano
- first_name: Chisa
  full_name: Kanno, Chisa
  last_name: Kanno
- first_name: Yuta
  full_name: Sakamoto, Yuta
  last_name: Sakamoto
- first_name: Masashi
  full_name: Ebihara, Masashi
  last_name: Ebihara
- first_name: Daria E
  full_name: Siekhaus, Daria E
  id: 3D224B9E-F248-11E8-B48F-1D18A9856A87
  last_name: Siekhaus
  orcid: 0000-0001-8323-8353
- first_name: Jiro
  full_name: Toshima, Jiro
  last_name: Toshima
citation:
  ama: Toshima J, Furuya E, Nagano M, et al. Yeast Eps15-like endocytic protein Pan1p
    regulates the interaction between endocytic vesicles, endosomes and the actin
    cytoskeleton. <i>eLife</i>. 2016;5(February 2016). doi:<a href="https://doi.org/10.7554/eLife.10276">10.7554/eLife.10276</a>
  apa: Toshima, J., Furuya, E., Nagano, M., Kanno, C., Sakamoto, Y., Ebihara, M.,
    … Toshima, J. (2016). Yeast Eps15-like endocytic protein Pan1p regulates the interaction
    between endocytic vesicles, endosomes and the actin cytoskeleton. <i>ELife</i>.
    eLife Sciences Publications. <a href="https://doi.org/10.7554/eLife.10276">https://doi.org/10.7554/eLife.10276</a>
  chicago: Toshima, Junko, Eri Furuya, Makoto Nagano, Chisa Kanno, Yuta Sakamoto,
    Masashi Ebihara, Daria E Siekhaus, and Jiro Toshima. “Yeast Eps15-like Endocytic
    Protein Pan1p Regulates the Interaction between Endocytic Vesicles, Endosomes
    and the Actin Cytoskeleton.” <i>ELife</i>. eLife Sciences Publications, 2016.
    <a href="https://doi.org/10.7554/eLife.10276">https://doi.org/10.7554/eLife.10276</a>.
  ieee: J. Toshima <i>et al.</i>, “Yeast Eps15-like endocytic protein Pan1p regulates
    the interaction between endocytic vesicles, endosomes and the actin cytoskeleton,”
    <i>eLife</i>, vol. 5, no. February 2016. eLife Sciences Publications, 2016.
  ista: Toshima J, Furuya E, Nagano M, Kanno C, Sakamoto Y, Ebihara M, Siekhaus DE,
    Toshima J. 2016. Yeast Eps15-like endocytic protein Pan1p regulates the interaction
    between endocytic vesicles, endosomes and the actin cytoskeleton. eLife. 5(February
    2016), e10276.
  mla: Toshima, Junko, et al. “Yeast Eps15-like Endocytic Protein Pan1p Regulates
    the Interaction between Endocytic Vesicles, Endosomes and the Actin Cytoskeleton.”
    <i>ELife</i>, vol. 5, no. February 2016, e10276, eLife Sciences Publications,
    2016, doi:<a href="https://doi.org/10.7554/eLife.10276">10.7554/eLife.10276</a>.
  short: J. Toshima, E. Furuya, M. Nagano, C. Kanno, Y. Sakamoto, M. Ebihara, D.E.
    Siekhaus, J. Toshima, ELife 5 (2016).
date_created: 2018-12-11T11:52:14Z
date_published: 2016-02-25T00:00:00Z
date_updated: 2021-01-12T06:50:59Z
day: '25'
ddc:
- '570'
department:
- _id: DaSi
doi: 10.7554/eLife.10276
ec_funded: 1
file:
- access_level: open_access
  checksum: d1cc44870580756ba8badd8e41adfdb5
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:10:08Z
  date_updated: 2020-07-14T12:44:56Z
  file_id: '4793'
  file_name: IST-2016-529-v1+1_elife-10276-v1.pdf
  file_size: 5198001
  relation: main_file
file_date_updated: 2020-07-14T12:44:56Z
has_accepted_license: '1'
intvolume: '         5'
issue: February 2016
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
project:
- _id: 2536F660-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '334077'
  name: Investigating the role of transporters in invasive migration through junctions
publication: eLife
publication_status: published
publisher: eLife Sciences Publications
publist_id: '5721'
pubrep_id: '529'
quality_controlled: '1'
scopus_import: 1
status: public
title: Yeast Eps15-like endocytic protein Pan1p regulates the interaction between
  endocytic vesicles, endosomes and the actin cytoskeleton
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 5
year: '2016'
...
---
_id: '1476'
abstract:
- lang: eng
  text: The dynamic assembly and disassembly of actin filaments is essential for the
    formation and transport of vesicles during endocytosis. In yeast, two types of
    actin structures, namely cortical patches and cytoplasmic cables, play a direct
    role in endocytosis, but how their interaction is regulated remains unclear. Here,
    we show that Srv2/CAP, an evolutionarily conserved actin regulator, is required
    for efficient endocytosis owing to its role in the formation of the actin patches
    that aid initial vesicle invagination and of the actin cables that these move
    along. Deletion of the SRV2 gene resulted in the appearance of aberrant fragmented
    actin cables that frequently moved past actin patches, the sites of endocytosis.
    We find that the C-terminal CARP domain of Srv2p is vitally important for the
    proper assembly of actin patches and cables; we also demonstrate that the N-terminal
    helical folded domain of Srv2 is required for its localization to actin patches,
    specifically to the ADP-actin rich region through an interaction with cofilin.
    These results demonstrate the in vivo roles of Srv2p in the regulation of the
    actin cytoskeleton during clathrin-mediated endocytosis
acknowledgement: We are grateful to Anthony Bretscher (Cornell University, NY) for
  providing the bni1-12 bnr1Δ (Y4135) strain. J.Y.T. was supported by a Japan Society
  for the Promotion of Science (JSPS) KAKENHI grant [grant number 26440067]; the Takeda
  Science Foundation; and the Novartis Foundation (Japan). J.T. was supported by a
  JSPS KAKENHI grant [grant number 25440054]; the Takeda Science Foundation; and the
  Kurata Memorial Hitachi Science and Technology Foundation. D.E.S. was supported
  by the European Union [grant number PCIG12-GA-2012-334077].
author:
- first_name: Junko
  full_name: Toshima, Junko
  last_name: Toshima
- first_name: Chika
  full_name: Horikomi, Chika
  last_name: Horikomi
- first_name: Asuka
  full_name: Okada, Asuka
  last_name: Okada
- first_name: Makiko
  full_name: Hatori, Makiko
  last_name: Hatori
- first_name: Makoto
  full_name: Nagano, Makoto
  last_name: Nagano
- first_name: Atsushi
  full_name: Masuda, Atsushi
  last_name: Masuda
- first_name: Wataru
  full_name: Yamamoto, Wataru
  last_name: Yamamoto
- first_name: Daria E
  full_name: Siekhaus, Daria E
  id: 3D224B9E-F248-11E8-B48F-1D18A9856A87
  last_name: Siekhaus
  orcid: 0000-0001-8323-8353
- first_name: Jiro
  full_name: Toshima, Jiro
  last_name: Toshima
citation:
  ama: Toshima J, Horikomi C, Okada A, et al. Srv2/CAP is required for polarized actin
    cable assembly and patch internalization during clathrin-mediated endocytosis.
    <i>Journal of Cell Science</i>. 2016;129(2):367-379. doi:<a href="https://doi.org/10.1242/jcs.176651">10.1242/jcs.176651</a>
  apa: Toshima, J., Horikomi, C., Okada, A., Hatori, M., Nagano, M., Masuda, A., …
    Toshima, J. (2016). Srv2/CAP is required for polarized actin cable assembly and
    patch internalization during clathrin-mediated endocytosis. <i>Journal of Cell
    Science</i>. Company of Biologists. <a href="https://doi.org/10.1242/jcs.176651">https://doi.org/10.1242/jcs.176651</a>
  chicago: Toshima, Junko, Chika Horikomi, Asuka Okada, Makiko Hatori, Makoto Nagano,
    Atsushi Masuda, Wataru Yamamoto, Daria E Siekhaus, and Jiro Toshima. “Srv2/CAP
    Is Required for Polarized Actin Cable Assembly and Patch Internalization during
    Clathrin-Mediated Endocytosis.” <i>Journal of Cell Science</i>. Company of Biologists,
    2016. <a href="https://doi.org/10.1242/jcs.176651">https://doi.org/10.1242/jcs.176651</a>.
  ieee: J. Toshima <i>et al.</i>, “Srv2/CAP is required for polarized actin cable
    assembly and patch internalization during clathrin-mediated endocytosis,” <i>Journal
    of Cell Science</i>, vol. 129, no. 2. Company of Biologists, pp. 367–379, 2016.
  ista: Toshima J, Horikomi C, Okada A, Hatori M, Nagano M, Masuda A, Yamamoto W,
    Siekhaus DE, Toshima J. 2016. Srv2/CAP is required for polarized actin cable assembly
    and patch internalization during clathrin-mediated endocytosis. Journal of Cell
    Science. 129(2), 367–379.
  mla: Toshima, Junko, et al. “Srv2/CAP Is Required for Polarized Actin Cable Assembly
    and Patch Internalization during Clathrin-Mediated Endocytosis.” <i>Journal of
    Cell Science</i>, vol. 129, no. 2, Company of Biologists, 2016, pp. 367–79, doi:<a
    href="https://doi.org/10.1242/jcs.176651">10.1242/jcs.176651</a>.
  short: J. Toshima, C. Horikomi, A. Okada, M. Hatori, M. Nagano, A. Masuda, W. Yamamoto,
    D.E. Siekhaus, J. Toshima, Journal of Cell Science 129 (2016) 367–379.
date_created: 2018-12-11T11:52:14Z
date_published: 2016-01-15T00:00:00Z
date_updated: 2021-01-12T06:51:00Z
day: '15'
ddc:
- '570'
- '576'
department:
- _id: DaSi
doi: 10.1242/jcs.176651
ec_funded: 1
file:
- access_level: open_access
  checksum: 2da0a09149a9ed956cdf79a95c17f08a
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:11:08Z
  date_updated: 2020-07-14T12:44:56Z
  file_id: '4861'
  file_name: IST-2017-767-v1+1_367.full.pdf
  file_size: 7176912
  relation: main_file
file_date_updated: 2020-07-14T12:44:56Z
has_accepted_license: '1'
intvolume: '       129'
issue: '2'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: 367 - 379
project:
- _id: 2536F660-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '334077'
  name: Investigating the role of transporters in invasive migration through junctions
publication: Journal of Cell Science
publication_status: published
publisher: Company of Biologists
publist_id: '5720'
pubrep_id: '767'
quality_controlled: '1'
scopus_import: 1
status: public
title: Srv2/CAP is required for polarized actin cable assembly and patch internalization
  during clathrin-mediated endocytosis
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 129
year: '2016'
...
---
_id: '1477'
abstract:
- lang: eng
  text: We consider partially observable Markov decision processes (POMDPs) with ω-regular
    conditions specified as parity objectives. The class of ω-regular languages provides
    a robust specification language to express properties in verification, and parity
    objectives are canonical forms to express them. The qualitative analysis problem
    given a POMDP and a parity objective asks whether there is a strategy to ensure
    that the objective is satisfied with probability 1 (resp. positive probability).
    While the qualitative analysis problems are undecidable even for special cases
    of parity objectives, we establish decidability (with optimal complexity) for
    POMDPs with all parity objectives under finite-memory strategies. We establish
    optimal (exponential) memory bounds and EXPTIME-completeness of the qualitative
    analysis problems under finite-memory strategies for POMDPs with parity objectives.
    We also present a practical approach, where we design heuristics to deal with
    the exponential complexity, and have applied our implementation on a number of
    POMDP examples.
arxiv: 1
author:
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Martin
  full_name: Chmelik, Martin
  id: 3624234E-F248-11E8-B48F-1D18A9856A87
  last_name: Chmelik
- first_name: Mathieu
  full_name: Tracol, Mathieu
  id: 3F54FA38-F248-11E8-B48F-1D18A9856A87
  last_name: Tracol
citation:
  ama: Chatterjee K, Chmelik M, Tracol M. What is decidable about partially observable
    Markov decision processes with ω-regular objectives. <i>Journal of Computer and
    System Sciences</i>. 2016;82(5):878-911. doi:<a href="https://doi.org/10.1016/j.jcss.2016.02.009">10.1016/j.jcss.2016.02.009</a>
  apa: Chatterjee, K., Chmelik, M., &#38; Tracol, M. (2016). What is decidable about
    partially observable Markov decision processes with ω-regular objectives. <i>Journal
    of Computer and System Sciences</i>. Elsevier. <a href="https://doi.org/10.1016/j.jcss.2016.02.009">https://doi.org/10.1016/j.jcss.2016.02.009</a>
  chicago: Chatterjee, Krishnendu, Martin Chmelik, and Mathieu Tracol. “What Is Decidable
    about Partially Observable Markov Decision Processes with ω-Regular Objectives.”
    <i>Journal of Computer and System Sciences</i>. Elsevier, 2016. <a href="https://doi.org/10.1016/j.jcss.2016.02.009">https://doi.org/10.1016/j.jcss.2016.02.009</a>.
  ieee: K. Chatterjee, M. Chmelik, and M. Tracol, “What is decidable about partially
    observable Markov decision processes with ω-regular objectives,” <i>Journal of
    Computer and System Sciences</i>, vol. 82, no. 5. Elsevier, pp. 878–911, 2016.
  ista: Chatterjee K, Chmelik M, Tracol M. 2016. What is decidable about partially
    observable Markov decision processes with ω-regular objectives. Journal of Computer
    and System Sciences. 82(5), 878–911.
  mla: Chatterjee, Krishnendu, et al. “What Is Decidable about Partially Observable
    Markov Decision Processes with ω-Regular Objectives.” <i>Journal of Computer and
    System Sciences</i>, vol. 82, no. 5, Elsevier, 2016, pp. 878–911, doi:<a href="https://doi.org/10.1016/j.jcss.2016.02.009">10.1016/j.jcss.2016.02.009</a>.
  short: K. Chatterjee, M. Chmelik, M. Tracol, Journal of Computer and System Sciences
    82 (2016) 878–911.
date_created: 2018-12-11T11:52:15Z
date_published: 2016-08-01T00:00:00Z
date_updated: 2023-02-23T12:24:38Z
day: '01'
department:
- _id: KrCh
doi: 10.1016/j.jcss.2016.02.009
ec_funded: 1
external_id:
  arxiv:
  - '1309.2802'
intvolume: '        82'
issue: '5'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1309.2802
month: '08'
oa: 1
oa_version: Preprint
page: 878 - 911
project:
- _id: 2584A770-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: P 23499-N23
  name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 25863FF4-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: S11407
  name: Game Theory
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '279307'
  name: 'Quantitative Graph Games: Theory and Applications'
- _id: 2587B514-B435-11E9-9278-68D0E5697425
  name: Microsoft Research Faculty Fellowship
publication: Journal of Computer and System Sciences
publication_status: published
publisher: Elsevier
publist_id: '5718'
quality_controlled: '1'
related_material:
  record:
  - id: '2295'
    relation: earlier_version
    status: public
  - id: '5400'
    relation: earlier_version
    status: public
scopus_import: 1
status: public
title: What is decidable about partially observable Markov decision processes with
  ω-regular objectives
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 82
year: '2016'
...
---
_id: '1478'
abstract:
- lang: eng
  text: We consider the Tonks-Girardeau gas subject to a random external potential.
    If the disorder is such that the underlying one-particle Hamiltonian displays
    localization (which is known to be generically the case), we show that there is
    exponential decay of correlations in the many-body eigenstates. Moreover, there
    is no Bose-Einstein condensation and no superfluidity, even at zero temperature.
article_number: '035002'
author:
- first_name: Robert
  full_name: Seiringer, Robert
  id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
  last_name: Seiringer
  orcid: 0000-0002-6781-0521
- first_name: Simone
  full_name: Warzel, Simone
  last_name: Warzel
citation:
  ama: Seiringer R, Warzel S. Decay of correlations and absence of superfluidity in
    the disordered Tonks-Girardeau gas. <i>New Journal of Physics</i>. 2016;18(3).
    doi:<a href="https://doi.org/10.1088/1367-2630/18/3/035002">10.1088/1367-2630/18/3/035002</a>
  apa: Seiringer, R., &#38; Warzel, S. (2016). Decay of correlations and absence of
    superfluidity in the disordered Tonks-Girardeau gas. <i>New Journal of Physics</i>.
    IOP Publishing Ltd. <a href="https://doi.org/10.1088/1367-2630/18/3/035002">https://doi.org/10.1088/1367-2630/18/3/035002</a>
  chicago: Seiringer, Robert, and Simone Warzel. “Decay of Correlations and Absence
    of Superfluidity in the Disordered Tonks-Girardeau Gas.” <i>New Journal of Physics</i>.
    IOP Publishing Ltd., 2016. <a href="https://doi.org/10.1088/1367-2630/18/3/035002">https://doi.org/10.1088/1367-2630/18/3/035002</a>.
  ieee: R. Seiringer and S. Warzel, “Decay of correlations and absence of superfluidity
    in the disordered Tonks-Girardeau gas,” <i>New Journal of Physics</i>, vol. 18,
    no. 3. IOP Publishing Ltd., 2016.
  ista: Seiringer R, Warzel S. 2016. Decay of correlations and absence of superfluidity
    in the disordered Tonks-Girardeau gas. New Journal of Physics. 18(3), 035002.
  mla: Seiringer, Robert, and Simone Warzel. “Decay of Correlations and Absence of
    Superfluidity in the Disordered Tonks-Girardeau Gas.” <i>New Journal of Physics</i>,
    vol. 18, no. 3, 035002, IOP Publishing Ltd., 2016, doi:<a href="https://doi.org/10.1088/1367-2630/18/3/035002">10.1088/1367-2630/18/3/035002</a>.
  short: R. Seiringer, S. Warzel, New Journal of Physics 18 (2016).
date_created: 2018-12-11T11:52:15Z
date_published: 2016-02-29T00:00:00Z
date_updated: 2021-01-12T06:51:01Z
day: '29'
ddc:
- '510'
- '530'
department:
- _id: RoSe
doi: 10.1088/1367-2630/18/3/035002
file:
- access_level: open_access
  checksum: 4f959eabc19d2a2f518318a450a4d424
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:17:22Z
  date_updated: 2020-07-14T12:44:56Z
  file_id: '5276'
  file_name: IST-2016-579-v1+1_njp_18_3_035002.pdf
  file_size: 965607
  relation: main_file
file_date_updated: 2020-07-14T12:44:56Z
has_accepted_license: '1'
intvolume: '        18'
issue: '3'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
project:
- _id: 25C878CE-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: P27533_N27
  name: Structure of the Excitation Spectrum for Many-Body Quantum Systems
publication: New Journal of Physics
publication_status: published
publisher: IOP Publishing Ltd.
publist_id: '5716'
pubrep_id: '579'
quality_controlled: '1'
scopus_import: 1
status: public
title: Decay of correlations and absence of superfluidity in the disordered Tonks-Girardeau
  gas
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 18
year: '2016'
...
---
_id: '1479'
abstract:
- lang: eng
  text: "Most entropy notions H(.) like Shannon or min-entropy satisfy a chain rule
    stating that for random variables X,Z, and A we have H(X|Z,A)≥H(X|Z)−|A|. That
    is, by conditioning on A the entropy of X can decrease by at most the bitlength
    |A| of A. Such chain rules are known to hold for some computational entropy notions
    like Yao’s and unpredictability-entropy. For HILL entropy, the computational analogue
    of min-entropy, the chain rule is of special interest and has found many applications,
    including leakage-resilient cryptography, deterministic encryption, and memory
    delegation. These applications rely on restricted special cases of the chain rule.
    Whether the chain rule for conditional HILL entropy holds in general was an open
    problem for which we give a strong negative answer: we construct joint distributions
    (X,Z,A), where A is a distribution over a single bit, such that the HILL entropy
    H HILL (X|Z) is large but H HILL (X|Z,A) is basically zero.\r\n\r\nOur counterexample
    just makes the minimal assumption that NP⊈P/poly. Under the stronger assumption
    that injective one-way function exist, we can make all the distributions efficiently
    samplable.\r\n\r\nFinally, we show that some more sophisticated cryptographic
    objects like lossy functions can be used to sample a distribution constituting
    a counterexample to the chain rule making only a single invocation to the underlying
    object."
acknowledgement: "This work was partly funded by the European Research Council under
  ERC Starting Grant 259668-PSPC and ERC Advanced Grant 321310-PERCY.\r\n"
author:
- first_name: Stephan
  full_name: Krenn, Stephan
  id: 329FCCF0-F248-11E8-B48F-1D18A9856A87
  last_name: Krenn
  orcid: 0000-0003-2835-9093
- first_name: Krzysztof Z
  full_name: Pietrzak, Krzysztof Z
  id: 3E04A7AA-F248-11E8-B48F-1D18A9856A87
  last_name: Pietrzak
  orcid: 0000-0002-9139-1654
- first_name: Akshay
  full_name: Wadia, Akshay
  last_name: Wadia
- first_name: Daniel
  full_name: Wichs, Daniel
  last_name: Wichs
citation:
  ama: Krenn S, Pietrzak KZ, Wadia A, Wichs D. A counterexample to the chain rule
    for conditional HILL entropy. <i>Computational Complexity</i>. 2016;25(3):567-605.
    doi:<a href="https://doi.org/10.1007/s00037-015-0120-9">10.1007/s00037-015-0120-9</a>
  apa: Krenn, S., Pietrzak, K. Z., Wadia, A., &#38; Wichs, D. (2016). A counterexample
    to the chain rule for conditional HILL entropy. <i>Computational Complexity</i>.
    Springer. <a href="https://doi.org/10.1007/s00037-015-0120-9">https://doi.org/10.1007/s00037-015-0120-9</a>
  chicago: Krenn, Stephan, Krzysztof Z Pietrzak, Akshay Wadia, and Daniel Wichs. “A
    Counterexample to the Chain Rule for Conditional HILL Entropy.” <i>Computational
    Complexity</i>. Springer, 2016. <a href="https://doi.org/10.1007/s00037-015-0120-9">https://doi.org/10.1007/s00037-015-0120-9</a>.
  ieee: S. Krenn, K. Z. Pietrzak, A. Wadia, and D. Wichs, “A counterexample to the
    chain rule for conditional HILL entropy,” <i>Computational Complexity</i>, vol.
    25, no. 3. Springer, pp. 567–605, 2016.
  ista: Krenn S, Pietrzak KZ, Wadia A, Wichs D. 2016. A counterexample to the chain
    rule for conditional HILL entropy. Computational Complexity. 25(3), 567–605.
  mla: Krenn, Stephan, et al. “A Counterexample to the Chain Rule for Conditional
    HILL Entropy.” <i>Computational Complexity</i>, vol. 25, no. 3, Springer, 2016,
    pp. 567–605, doi:<a href="https://doi.org/10.1007/s00037-015-0120-9">10.1007/s00037-015-0120-9</a>.
  short: S. Krenn, K.Z. Pietrzak, A. Wadia, D. Wichs, Computational Complexity 25
    (2016) 567–605.
date_created: 2018-12-11T11:52:16Z
date_published: 2016-09-01T00:00:00Z
date_updated: 2023-02-23T11:05:09Z
day: '01'
ddc:
- '004'
department:
- _id: KrPi
doi: 10.1007/s00037-015-0120-9
ec_funded: 1
file:
- access_level: open_access
  checksum: 7659296174fa75f5f0364f31f46f4bcf
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:13:29Z
  date_updated: 2020-07-14T12:44:56Z
  file_id: '5012'
  file_name: IST-2017-766-v1+1_678.pdf
  file_size: 483258
  relation: main_file
file_date_updated: 2020-07-14T12:44:56Z
has_accepted_license: '1'
intvolume: '        25'
issue: '3'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Submitted Version
page: 567 - 605
project:
- _id: 258C570E-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '259668'
  name: Provable Security for Physical Cryptography
publication: Computational Complexity
publication_status: published
publisher: Springer
publist_id: '5715'
pubrep_id: '766'
quality_controlled: '1'
related_material:
  record:
  - id: '2940'
    relation: earlier_version
    status: public
scopus_import: 1
status: public
title: A counterexample to the chain rule for conditional HILL entropy
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 25
year: '2016'
...
---
_id: '1480'
abstract:
- lang: eng
  text: 'Exponential varieties arise from exponential families in statistics. These
    real algebraic varieties have strong positivity and convexity properties, familiar
    from toric varieties and their moment maps. Among them are varieties of inverses
    of symmetric matrices satisfying linear constraints. This class includes Gaussian
    graphical models. We develop a general theory of exponential varieties. These
    are derived from hyperbolic polynomials and their integral representations. We
    compare the multidegrees and ML degrees of the gradient map for hyperbolic polynomials. '
author:
- first_name: Mateusz
  full_name: Michałek, Mateusz
  last_name: Michałek
- first_name: Bernd
  full_name: Sturmfels, Bernd
  last_name: Sturmfels
- first_name: Caroline
  full_name: Uhler, Caroline
  id: 49ADD78E-F248-11E8-B48F-1D18A9856A87
  last_name: Uhler
  orcid: 0000-0002-7008-0216
- first_name: Piotr
  full_name: Zwiernik, Piotr
  last_name: Zwiernik
citation:
  ama: Michałek M, Sturmfels B, Uhler C, Zwiernik P. Exponential varieties. <i>Proceedings
    of the London Mathematical Society</i>. 2016;112(1):27-56. doi:<a href="https://doi.org/10.1112/plms/pdv066">10.1112/plms/pdv066</a>
  apa: Michałek, M., Sturmfels, B., Uhler, C., &#38; Zwiernik, P. (2016). Exponential
    varieties. <i>Proceedings of the London Mathematical Society</i>. Oxford University
    Press. <a href="https://doi.org/10.1112/plms/pdv066">https://doi.org/10.1112/plms/pdv066</a>
  chicago: Michałek, Mateusz, Bernd Sturmfels, Caroline Uhler, and Piotr Zwiernik.
    “Exponential Varieties.” <i>Proceedings of the London Mathematical Society</i>.
    Oxford University Press, 2016. <a href="https://doi.org/10.1112/plms/pdv066">https://doi.org/10.1112/plms/pdv066</a>.
  ieee: M. Michałek, B. Sturmfels, C. Uhler, and P. Zwiernik, “Exponential varieties,”
    <i>Proceedings of the London Mathematical Society</i>, vol. 112, no. 1. Oxford
    University Press, pp. 27–56, 2016.
  ista: Michałek M, Sturmfels B, Uhler C, Zwiernik P. 2016. Exponential varieties.
    Proceedings of the London Mathematical Society. 112(1), 27–56.
  mla: Michałek, Mateusz, et al. “Exponential Varieties.” <i>Proceedings of the London
    Mathematical Society</i>, vol. 112, no. 1, Oxford University Press, 2016, pp.
    27–56, doi:<a href="https://doi.org/10.1112/plms/pdv066">10.1112/plms/pdv066</a>.
  short: M. Michałek, B. Sturmfels, C. Uhler, P. Zwiernik, Proceedings of the London
    Mathematical Society 112 (2016) 27–56.
date_created: 2018-12-11T11:52:16Z
date_published: 2016-01-07T00:00:00Z
date_updated: 2021-01-12T06:51:02Z
day: '07'
department:
- _id: CaUh
doi: 10.1112/plms/pdv066
intvolume: '       112'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: http://arxiv.org/abs/1412.6185
month: '01'
oa: 1
oa_version: Preprint
page: 27 - 56
publication: Proceedings of the London Mathematical Society
publication_status: published
publisher: Oxford University Press
publist_id: '5714'
quality_controlled: '1'
scopus_import: 1
status: public
title: Exponential varieties
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 112
year: '2016'
...
---
_id: '1482'
abstract:
- lang: eng
  text: Plants have the ability to continously generate new organs by maintaining
    populations of stem cells throught their lives. The shoot apical meristem (SAM)
    provides a stable environment for the maintenance of stem cells. All cells inside
    the SAM divide, yet boundaries and patterns are maintained. Experimental evidence
    indicates that patterning is independent of cell lineage, thus a dynamic self-regulatory
    mechanism is required. A pivotal role in the organization of the SAM is played
    by the WUSCHEL gene (WUS). An important question in this regard is that how WUS
    expression is positioned in the SAM via a cell-lineage independent signaling mechanism.
    In this study we demonstrate via mathematical modeling that a combination of an
    inhibitor of the Cytokinin (CK) receptor, Arabidopsis histidine kinase 4 (AHK4)
    and two morphogens originating from the top cell layer, can plausibly account
    for the cell lineage-independent centering of WUS expression within SAM. Furthermore,
    our laser ablation and microsurgical experiments support the hypothesis that patterning
    in SAM occurs at the level of CK reception and signaling. The model suggests that
    the interplay between CK signaling, WUS/CLV feedback loop and boundary signals
    can account for positioning of the WUS expression, and provides directions for
    further experimental investigation.
acknowledgement: We thank J. Traas, B. Müller and V. Reddy for providing seed materials
  and Y. Deb for advice regarding the laser ablation experiments. We specially thank
  Thomas Laux for stimulating discussions and support in the initial phase of this
  project.
article_number: e0147830
author:
- first_name: Milad
  full_name: Adibi, Milad
  last_name: Adibi
- first_name: Saiko
  full_name: Yoshida, Saiko
  id: 2E46069C-F248-11E8-B48F-1D18A9856A87
  last_name: Yoshida
- first_name: Dolf
  full_name: Weijers, Dolf
  last_name: Weijers
- first_name: Christian
  full_name: Fleck, Christian
  last_name: Fleck
citation:
  ama: Adibi M, Yoshida S, Weijers D, Fleck C. Centering the organizing center in
    the Arabidopsis thaliana shoot apical meristem by a combination of cytokinin signaling
    and self-organization. <i>PLoS One</i>. 2016;11(2). doi:<a href="https://doi.org/10.1371/journal.pone.0147830">10.1371/journal.pone.0147830</a>
  apa: Adibi, M., Yoshida, S., Weijers, D., &#38; Fleck, C. (2016). Centering the
    organizing center in the Arabidopsis thaliana shoot apical meristem by a combination
    of cytokinin signaling and self-organization. <i>PLoS One</i>. Public Library
    of Science. <a href="https://doi.org/10.1371/journal.pone.0147830">https://doi.org/10.1371/journal.pone.0147830</a>
  chicago: Adibi, Milad, Saiko Yoshida, Dolf Weijers, and Christian Fleck. “Centering
    the Organizing Center in the Arabidopsis Thaliana Shoot Apical Meristem by a Combination
    of Cytokinin Signaling and Self-Organization.” <i>PLoS One</i>. Public Library
    of Science, 2016. <a href="https://doi.org/10.1371/journal.pone.0147830">https://doi.org/10.1371/journal.pone.0147830</a>.
  ieee: M. Adibi, S. Yoshida, D. Weijers, and C. Fleck, “Centering the organizing
    center in the Arabidopsis thaliana shoot apical meristem by a combination of cytokinin
    signaling and self-organization,” <i>PLoS One</i>, vol. 11, no. 2. Public Library
    of Science, 2016.
  ista: Adibi M, Yoshida S, Weijers D, Fleck C. 2016. Centering the organizing center
    in the Arabidopsis thaliana shoot apical meristem by a combination of cytokinin
    signaling and self-organization. PLoS One. 11(2), e0147830.
  mla: Adibi, Milad, et al. “Centering the Organizing Center in the Arabidopsis Thaliana
    Shoot Apical Meristem by a Combination of Cytokinin Signaling and Self-Organization.”
    <i>PLoS One</i>, vol. 11, no. 2, e0147830, Public Library of Science, 2016, doi:<a
    href="https://doi.org/10.1371/journal.pone.0147830">10.1371/journal.pone.0147830</a>.
  short: M. Adibi, S. Yoshida, D. Weijers, C. Fleck, PLoS One 11 (2016).
date_created: 2018-12-11T11:52:17Z
date_published: 2016-02-01T00:00:00Z
date_updated: 2021-01-12T06:51:03Z
day: '01'
ddc:
- '570'
department:
- _id: JiFr
doi: 10.1371/journal.pone.0147830
file:
- access_level: open_access
  checksum: 6066146e527335030f83aa5924ab72a6
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:14:16Z
  date_updated: 2020-07-14T12:44:57Z
  file_id: '5066'
  file_name: IST-2016-521-v1+1_journal.pone.0147830.PDF
  file_size: 4297148
  relation: main_file
file_date_updated: 2020-07-14T12:44:57Z
has_accepted_license: '1'
intvolume: '        11'
issue: '2'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
publication: PLoS One
publication_status: published
publisher: Public Library of Science
publist_id: '5711'
pubrep_id: '521'
quality_controlled: '1'
scopus_import: 1
status: public
title: Centering the organizing center in the Arabidopsis thaliana shoot apical meristem
  by a combination of cytokinin signaling and self-organization
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 11
year: '2016'
...
