---
_id: '479'
abstract:
- lang: eng
  text: Clinical guidelines and decision support systems (DSS) play an important role
    in daily practices of medicine. Many text-based guidelines have been encoded for
    work-flow simulation of DSS to automate health care. During the collaboration
    with Carle hospital to develop a DSS, we identify that, for some complex and life-critical
    diseases, it is highly desirable to automatically rigorously verify some complex
    temporal properties in guidelines, which brings new challenges to current simulation
    based DSS with limited support of automatical formal verification and real-time
    data analysis. In this paper, we conduct the first study on applying runtime verification
    to cooperate with current DSS based on real-time data. Within the proposed technique,
    a user-friendly domain specific language, named DRTV, is designed to specify vital
    real-time data sampled by medical devices and temporal properties originated from
    clinical guidelines. Some interfaces are developed for data acquisition and communication.
    Then, for medical practice scenarios described in DRTV model, we will automatically
    generate event sequences and runtime property verifier automata. If a temporal
    property violates, real-time warnings will be produced by the formal verifier
    and passed to medical DSS. We have used DRTV to specify different kinds of medical
    care scenarios, and applied the proposed technique to assist existing DSS. As
    presented in experiment results, in terms of warning detection, it outperforms
    the only use of DSS or human inspection, and improves the quality of clinical
    health care of hospital
acknowledgement: "This work is supported by NSF CNS 13-30077, NSF CNS 13-29886, NSF
  CNS 15-45002, and NSFC 61303014.\r\nThe authors thank Dr.  Bobby and Dr.  Hill at
  Carle Hospital, Urbana, IL for their help with the discussion on medical  knowledge.\r\n\r\n"
alternative_title:
- Proceedings International Conference on Software Engineering
author:
- first_name: Yu
  full_name: Jiang, Yu
  last_name: Jiang
- first_name: Han
  full_name: Liu, Han
  last_name: Liu
- first_name: Hui
  full_name: Kong, Hui
  id: 3BDE25AA-F248-11E8-B48F-1D18A9856A87
  last_name: Kong
  orcid: 0000-0002-3066-6941
- first_name: Rui
  full_name: Wang, Rui
  last_name: Wang
- first_name: Mohamad
  full_name: Hosseini, Mohamad
  last_name: Hosseini
- first_name: Jiaguang
  full_name: Sun, Jiaguang
  last_name: Sun
- first_name: Lui
  full_name: Sha, Lui
  last_name: Sha
citation:
  ama: 'Jiang Y, Liu H, Kong H, et al. Use runtime verification to improve the quality
    of medical care practice. In: <i>Proceedings of the 38th International Conference
    on Software Engineering Companion </i>. IEEE; 2016:112-121. doi:<a href="https://doi.org/10.1145/2889160.2889233">10.1145/2889160.2889233</a>'
  apa: 'Jiang, Y., Liu, H., Kong, H., Wang, R., Hosseini, M., Sun, J., &#38; Sha,
    L. (2016). Use runtime verification to improve the quality of medical care practice.
    In <i>Proceedings of the 38th International Conference on Software Engineering
    Companion </i> (pp. 112–121). Austin, TX, USA: IEEE. <a href="https://doi.org/10.1145/2889160.2889233">https://doi.org/10.1145/2889160.2889233</a>'
  chicago: Jiang, Yu, Han Liu, Hui Kong, Rui Wang, Mohamad Hosseini, Jiaguang Sun,
    and Lui Sha. “Use Runtime Verification to Improve the Quality of Medical Care
    Practice.” In <i>Proceedings of the 38th International Conference on Software
    Engineering Companion </i>, 112–21. IEEE, 2016. <a href="https://doi.org/10.1145/2889160.2889233">https://doi.org/10.1145/2889160.2889233</a>.
  ieee: Y. Jiang <i>et al.</i>, “Use runtime verification to improve the quality of
    medical care practice,” in <i>Proceedings of the 38th International Conference
    on Software Engineering Companion </i>, Austin, TX, USA, 2016, pp. 112–121.
  ista: 'Jiang Y, Liu H, Kong H, Wang R, Hosseini M, Sun J, Sha L. 2016. Use runtime
    verification to improve the quality of medical care practice. Proceedings of the
    38th International Conference on Software Engineering Companion . ICSE: International
    Conference on Software Engineering, Proceedings International Conference on Software
    Engineering, , 112–121.'
  mla: Jiang, Yu, et al. “Use Runtime Verification to Improve the Quality of Medical
    Care Practice.” <i>Proceedings of the 38th International Conference on Software
    Engineering Companion </i>, IEEE, 2016, pp. 112–21, doi:<a href="https://doi.org/10.1145/2889160.2889233">10.1145/2889160.2889233</a>.
  short: Y. Jiang, H. Liu, H. Kong, R. Wang, M. Hosseini, J. Sun, L. Sha, in:, Proceedings
    of the 38th International Conference on Software Engineering Companion , IEEE,
    2016, pp. 112–121.
conference:
  end_date: 2016-05-22
  location: Austin, TX, USA
  name: 'ICSE: International Conference on Software Engineering'
  start_date: 2016-05-14
date_created: 2018-12-11T11:46:42Z
date_published: 2016-05-14T00:00:00Z
date_updated: 2021-01-12T08:00:55Z
day: '14'
department:
- _id: ToHe
doi: 10.1145/2889160.2889233
language:
- iso: eng
month: '05'
oa_version: None
page: 112 - 121
publication: 'Proceedings of the 38th International Conference on Software Engineering
  Companion '
publication_status: published
publisher: IEEE
publist_id: '7341'
quality_controlled: '1'
scopus_import: 1
status: public
title: Use runtime verification to improve the quality of medical care practice
type: conference
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
year: '2016'
...
---
_id: '480'
abstract:
- lang: eng
  text: Graph games provide the foundation for modeling and synthesizing reactive
    processes. In the synthesis of stochastic reactive processes, the traditional
    model is perfect-information stochastic games, where some transitions of the game
    graph are controlled by two adversarial players, and the other transitions are
    executed probabilistically. We consider such games where the objective is the
    conjunction of several quantitative objectives (specified as mean-payoff conditions),
    which we refer to as generalized mean-payoff objectives. The basic decision problem
    asks for the existence of a finite-memory strategy for a player that ensures the
    generalized mean-payoff objective be satisfied with a desired probability against
    all strategies of the opponent. A special case of the decision problem is the
    almost-sure problem where the desired probability is 1. Previous results presented
    a semi-decision procedure for -approximations of the almost-sure problem. In this
    work, we show that both the almost-sure problem as well as the general basic decision
    problem are coNP-complete, significantly improving the previous results. Moreover,
    we show that in the case of 1-player stochastic games, randomized memoryless strategies
    are sufficient and the problem can be solved in polynomial time. In contrast,
    in two-player stochastic games, we show that even with randomized strategies exponential
    memory is required in general, and present a matching exponential upper bound.
    We also study the basic decision problem with infinite-memory strategies and present
    computational complexity results for the problem. Our results are relevant in
    the synthesis of stochastic reactive systems with multiple quantitative requirements.
alternative_title:
- Proceedings Symposium on Logic in Computer Science
author:
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Laurent
  full_name: Doyen, Laurent
  last_name: Doyen
citation:
  ama: 'Chatterjee K, Doyen L. Perfect-information stochastic games with generalized
    mean-payoff objectives. In: Vol 05-08-July-2016. IEEE; 2016:247-256. doi:<a href="https://doi.org/10.1145/2933575.2934513">10.1145/2933575.2934513</a>'
  apa: 'Chatterjee, K., &#38; Doyen, L. (2016). Perfect-information stochastic games
    with generalized mean-payoff objectives (Vol. 05-08-July-2016, pp. 247–256). Presented
    at the LICS: Logic in Computer Science, New York, NY, USA: IEEE. <a href="https://doi.org/10.1145/2933575.2934513">https://doi.org/10.1145/2933575.2934513</a>'
  chicago: Chatterjee, Krishnendu, and Laurent Doyen. “Perfect-Information Stochastic
    Games with Generalized Mean-Payoff Objectives,” 05-08-July-2016:247–56. IEEE,
    2016. <a href="https://doi.org/10.1145/2933575.2934513">https://doi.org/10.1145/2933575.2934513</a>.
  ieee: 'K. Chatterjee and L. Doyen, “Perfect-information stochastic games with generalized
    mean-payoff objectives,” presented at the LICS: Logic in Computer Science, New
    York, NY, USA, 2016, vol. 05-08-July-2016, pp. 247–256.'
  ista: 'Chatterjee K, Doyen L. 2016. Perfect-information stochastic games with generalized
    mean-payoff objectives. LICS: Logic in Computer Science, Proceedings Symposium
    on Logic in Computer Science, vol. 05-08-July-2016, 247–256.'
  mla: Chatterjee, Krishnendu, and Laurent Doyen. <i>Perfect-Information Stochastic
    Games with Generalized Mean-Payoff Objectives</i>. Vol. 05-08-July-2016, IEEE,
    2016, pp. 247–56, doi:<a href="https://doi.org/10.1145/2933575.2934513">10.1145/2933575.2934513</a>.
  short: K. Chatterjee, L. Doyen, in:, IEEE, 2016, pp. 247–256.
conference:
  end_date: 2016-07-08
  location: New York, NY, USA
  name: 'LICS: Logic in Computer Science'
  start_date: 2016-07-05
date_created: 2018-12-11T11:46:42Z
date_published: 2016-07-05T00:00:00Z
date_updated: 2021-01-12T08:00:56Z
day: '05'
department:
- _id: KrCh
doi: 10.1145/2933575.2934513
ec_funded: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1604.06376
month: '07'
oa: 1
oa_version: Preprint
page: 247 - 256
project:
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: S 11407_N23
  name: Rigorous Systems Engineering
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '279307'
  name: 'Quantitative Graph Games: Theory and Applications'
- _id: 25892FC0-B435-11E9-9278-68D0E5697425
  grant_number: ICT15-003
  name: Efficient Algorithms for Computer Aided Verification
publication_status: published
publisher: IEEE
publist_id: '7340'
quality_controlled: '1'
scopus_import: 1
status: public
title: Perfect-information stochastic games with generalized mean-payoff objectives
type: conference
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 05-08-July-2016
year: '2016'
...
---
_id: '482'
abstract:
- lang: eng
  text: Nonlinear electro-optical conversion of microwave radiation into the optical
    telecommunication band is achieved within a crystalline whispering gallery mode
    resonator, reaching 0.1% photon number conversion efficiency with MHz bandwidth.
alternative_title:
- Optics InfoBase Conference Papers
article_processing_charge: No
author:
- first_name: Alfredo
  full_name: Rueda, Alfredo
  last_name: Rueda
- first_name: Florian
  full_name: Sedlmeir, Florian
  last_name: Sedlmeir
- first_name: Michele
  full_name: Collodo, Michele
  last_name: Collodo
- first_name: Ulrich
  full_name: Vogl, Ulrich
  last_name: Vogl
- first_name: Birgit
  full_name: Stiller, Birgit
  last_name: Stiller
- first_name: Gerhard
  full_name: Schunk, Gerhard
  last_name: Schunk
- first_name: Dmitry
  full_name: Strekalov, Dmitry
  last_name: Strekalov
- first_name: Christoph
  full_name: Marquardt, Christoph
  last_name: Marquardt
- first_name: Johannes M
  full_name: Fink, Johannes M
  id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
  last_name: Fink
  orcid: 0000-0001-8112-028X
- first_name: Oskar
  full_name: Painter, Oskar
  last_name: Painter
- first_name: Gerd
  full_name: Leuchs, Gerd
  last_name: Leuchs
- first_name: Harald
  full_name: Schwefel, Harald
  last_name: Schwefel
citation:
  ama: 'Rueda A, Sedlmeir F, Collodo M, et al. Nonlinear single sideband microwave
    to optical conversion using an electro-optic WGM-resonator. In: Optica Publishing
    Group; 2016. doi:<a href="https://doi.org/10.1364/NP.2016.NTh3A.6">10.1364/NP.2016.NTh3A.6</a>'
  apa: 'Rueda, A., Sedlmeir, F., Collodo, M., Vogl, U., Stiller, B., Schunk, G., …
    Schwefel, H. (2016). Nonlinear single sideband microwave to optical conversion
    using an electro-optic WGM-resonator. Presented at the NP: Nonlinear Photonics,
    Sydney, Australia: Optica Publishing Group. <a href="https://doi.org/10.1364/NP.2016.NTh3A.6">https://doi.org/10.1364/NP.2016.NTh3A.6</a>'
  chicago: Rueda, Alfredo, Florian Sedlmeir, Michele Collodo, Ulrich Vogl, Birgit
    Stiller, Gerhard Schunk, Dmitry Strekalov, et al. “Nonlinear Single Sideband Microwave
    to Optical Conversion Using an Electro-Optic WGM-Resonator.” Optica Publishing
    Group, 2016. <a href="https://doi.org/10.1364/NP.2016.NTh3A.6">https://doi.org/10.1364/NP.2016.NTh3A.6</a>.
  ieee: 'A. Rueda <i>et al.</i>, “Nonlinear single sideband microwave to optical conversion
    using an electro-optic WGM-resonator,” presented at the NP: Nonlinear Photonics,
    Sydney, Australia, 2016.'
  ista: 'Rueda A, Sedlmeir F, Collodo M, Vogl U, Stiller B, Schunk G, Strekalov D,
    Marquardt C, Fink JM, Painter O, Leuchs G, Schwefel H. 2016. Nonlinear single
    sideband microwave to optical conversion using an electro-optic WGM-resonator.
    NP: Nonlinear Photonics, Optics InfoBase Conference Papers, .'
  mla: Rueda, Alfredo, et al. <i>Nonlinear Single Sideband Microwave to Optical Conversion
    Using an Electro-Optic WGM-Resonator</i>. Optica Publishing Group, 2016, doi:<a
    href="https://doi.org/10.1364/NP.2016.NTh3A.6">10.1364/NP.2016.NTh3A.6</a>.
  short: A. Rueda, F. Sedlmeir, M. Collodo, U. Vogl, B. Stiller, G. Schunk, D. Strekalov,
    C. Marquardt, J.M. Fink, O. Painter, G. Leuchs, H. Schwefel, in:, Optica Publishing
    Group, 2016.
conference:
  end_date: 2016-09-08
  location: Sydney, Australia
  name: 'NP: Nonlinear Photonics'
  start_date: 2016-09-05
date_created: 2018-12-11T11:46:43Z
date_published: 2016-08-29T00:00:00Z
date_updated: 2023-10-17T12:16:43Z
day: '29'
department:
- _id: JoFi
doi: 10.1364/NP.2016.NTh3A.6
language:
- iso: eng
month: '08'
oa_version: None
publication_status: published
publisher: Optica Publishing Group
publist_id: '7339'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Nonlinear single sideband microwave to optical conversion using an electro-optic
  WGM-resonator
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2016'
...
---
_id: '510'
abstract:
- lang: eng
  text: 'The CLE (CLAVATA3/Embryo Surrounding Region-related) peptides are small secreted
    signaling peptides that are primarily involved in the regulation of stem cell
    homeostasis in different plant meristems. Particularly, the characterization of
    the CLE41-PXY/TDR signaling pathway has greatly advanced our understanding on
    the potential roles of CLE peptides in vascular development and wood formation.
    Nevertheless, our knowledge on this gene family in a tree species is limited.
    In a recent study, we reported on a systematically investigation of the CLE gene
    family in Populus trichocarpa . The potential roles of PtCLE genes were studied
    by comparative analysis and transcriptional pro fi ling. Among fi fty PtCLE members,
    many PtCLE proteins share identical CLE motifs or contain the same CLE motif as
    that of AtCLEs, while PtCLE genes exhibited either comparable or distinct expression
    patterns comparing to their Arabidopsis counterparts. These fi ndings indicate
    the existence of both functional conservation and functional divergence between
    PtCLEs and their AtCLE orthologues. Our results provide valuable resources for
    future functional investigations of these critical signaling molecules in woody
    plants. '
acknowledgement: 'We are grateful to Dr. Long (Laboratoire de Reproduction et Developpement
  des Plantes,CNRS,INRA,ENSLyon,UCBL,Universite de Lyon,France)for critical reading
  of the article. Work in our group is supported by the National Natural Science Foundation
  of China (31271575; 31200902), the Fundamental Research Funds for the Central Univ
  ersities (GK201103005), the Specialized Research Fund for the Doctoral Program of
  Higher Education from the Ministry of Education of China (20120202120009), the Scientific
  Research Foundation for the Returned Overseas Chinese Scholars, State Education
  Ministry, and the Natural Science Basic Research Plan in Shaanxi Province of China
  (2014JM3064). '
article_number: e1191734
article_processing_charge: No
author:
- first_name: Zhijun
  full_name: Liu, Zhijun
  last_name: Liu
- first_name: 'Nan'
  full_name: Yang, Nan
  last_name: Yang
- first_name: Yanting
  full_name: Lv, Yanting
  last_name: Lv
- first_name: Lixia
  full_name: Pan, Lixia
  last_name: Pan
- first_name: Shuo
  full_name: Lv, Shuo
  last_name: Lv
- first_name: Huibin
  full_name: Han, Huibin
  id: 31435098-F248-11E8-B48F-1D18A9856A87
  last_name: Han
- first_name: Guodong
  full_name: Wang, Guodong
  last_name: Wang
citation:
  ama: Liu Z, Yang N, Lv Y, et al. The CLE gene family in Populus trichocarpa. <i>Plant
    Signaling &#38; Behavior</i>. 2016;11(6). doi:<a href="https://doi.org/10.1080/15592324.2016.1191734">10.1080/15592324.2016.1191734</a>
  apa: Liu, Z., Yang, N., Lv, Y., Pan, L., Lv, S., Han, H., &#38; Wang, G. (2016).
    The CLE gene family in Populus trichocarpa. <i>Plant Signaling &#38; Behavior</i>.
    Taylor &#38; Francis. <a href="https://doi.org/10.1080/15592324.2016.1191734">https://doi.org/10.1080/15592324.2016.1191734</a>
  chicago: Liu, Zhijun, Nan Yang, Yanting Lv, Lixia Pan, Shuo Lv, Huibin Han, and
    Guodong Wang. “The CLE Gene Family in Populus Trichocarpa.” <i>Plant Signaling
    &#38; Behavior</i>. Taylor &#38; Francis, 2016. <a href="https://doi.org/10.1080/15592324.2016.1191734">https://doi.org/10.1080/15592324.2016.1191734</a>.
  ieee: Z. Liu <i>et al.</i>, “The CLE gene family in Populus trichocarpa,” <i>Plant
    Signaling &#38; Behavior</i>, vol. 11, no. 6. Taylor &#38; Francis, 2016.
  ista: Liu Z, Yang N, Lv Y, Pan L, Lv S, Han H, Wang G. 2016. The CLE gene family
    in Populus trichocarpa. Plant Signaling &#38; Behavior. 11(6), e1191734.
  mla: Liu, Zhijun, et al. “The CLE Gene Family in Populus Trichocarpa.” <i>Plant
    Signaling &#38; Behavior</i>, vol. 11, no. 6, e1191734, Taylor &#38; Francis,
    2016, doi:<a href="https://doi.org/10.1080/15592324.2016.1191734">10.1080/15592324.2016.1191734</a>.
  short: Z. Liu, N. Yang, Y. Lv, L. Pan, S. Lv, H. Han, G. Wang, Plant Signaling &#38;
    Behavior 11 (2016).
date_created: 2018-12-11T11:46:53Z
date_published: 2016-06-02T00:00:00Z
date_updated: 2023-10-17T11:13:40Z
day: '02'
department:
- _id: JiFr
doi: 10.1080/15592324.2016.1191734
intvolume: '        11'
issue: '6'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973754/
month: '06'
oa: 1
oa_version: Submitted Version
publication: Plant Signaling & Behavior
publication_status: published
publisher: Taylor & Francis
publist_id: '7308'
quality_controlled: '1'
scopus_import: '1'
status: public
title: The CLE gene family in Populus trichocarpa
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 11
year: '2016'
...
---
_id: '5445'
abstract:
- lang: eng
  text: 'We consider the quantitative analysis problem for interprocedural control-flow
    graphs (ICFGs). The input consists of an ICFG, a positive weight function that
    assigns every transition a positive integer-valued number, and a labelling of
    the transitions (events) as good, bad, and neutral events. The weight function
    assigns to each transition a numerical value that represents ameasure of how good
    or bad an event is. The quantitative analysis problem asks whether there is a
    run of the ICFG where the ratio of the sum of the numerical weights of good events
    versus the sum of weights of bad events in the long-run is at least a given threshold
    (or equivalently, to compute the maximal ratio among all valid paths in the ICFG).
    The quantitative analysis problem for ICFGs can be solved in polynomial time,
    and we present an efficient and practical algorithm for the problem. We show that
    several problems relevant for static program analysis, such as estimating the
    worst-case execution time of a program or the average energy consumption of a
    mobile application, can be modeled in our framework. We have implemented our algorithm
    as a tool in the Java Soot framework. We demonstrate the effectiveness of our
    approach with two case studies. First, we show that our framework provides a sound
    approach (no false positives) for the analysis of inefficiently-used containers.
    Second, we show that our approach can also be used for static profiling of programs
    which reasons about methods that are frequently invoked. Our experimental results
    show that our tool scales to relatively large benchmarks, and discovers relevant
    and useful information that can be used to optimize performance of the programs. '
alternative_title:
- IST Austria Technical Report
author:
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Andreas
  full_name: Pavlogiannis, Andreas
  id: 49704004-F248-11E8-B48F-1D18A9856A87
  last_name: Pavlogiannis
  orcid: 0000-0002-8943-0722
- first_name: Yaron
  full_name: Velner, Yaron
  last_name: Velner
citation:
  ama: Chatterjee K, Pavlogiannis A, Velner Y. <i>Quantitative Interprocedural Analysis</i>.
    IST Austria; 2016. doi:<a href="https://doi.org/10.15479/AT:IST-2016-523-v1-1">10.15479/AT:IST-2016-523-v1-1</a>
  apa: Chatterjee, K., Pavlogiannis, A., &#38; Velner, Y. (2016). <i>Quantitative
    interprocedural analysis</i>. IST Austria. <a href="https://doi.org/10.15479/AT:IST-2016-523-v1-1">https://doi.org/10.15479/AT:IST-2016-523-v1-1</a>
  chicago: Chatterjee, Krishnendu, Andreas Pavlogiannis, and Yaron Velner. <i>Quantitative
    Interprocedural Analysis</i>. IST Austria, 2016. <a href="https://doi.org/10.15479/AT:IST-2016-523-v1-1">https://doi.org/10.15479/AT:IST-2016-523-v1-1</a>.
  ieee: K. Chatterjee, A. Pavlogiannis, and Y. Velner, <i>Quantitative interprocedural
    analysis</i>. IST Austria, 2016.
  ista: Chatterjee K, Pavlogiannis A, Velner Y. 2016. Quantitative interprocedural
    analysis, IST Austria, 33p.
  mla: Chatterjee, Krishnendu, et al. <i>Quantitative Interprocedural Analysis</i>.
    IST Austria, 2016, doi:<a href="https://doi.org/10.15479/AT:IST-2016-523-v1-1">10.15479/AT:IST-2016-523-v1-1</a>.
  short: K. Chatterjee, A. Pavlogiannis, Y. Velner, Quantitative Interprocedural Analysis,
    IST Austria, 2016.
date_created: 2018-12-12T11:39:22Z
date_published: 2016-03-31T00:00:00Z
date_updated: 2023-02-23T10:06:22Z
day: '31'
ddc:
- '005'
department:
- _id: KrCh
doi: 10.15479/AT:IST-2016-523-v1-1
file:
- access_level: open_access
  checksum: cef516fa091925b5868813e355268fb4
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T11:53:52Z
  date_updated: 2020-07-14T12:46:58Z
  file_id: '5513'
  file_name: IST-2016-523-v1+1_main.pdf
  file_size: 1012204
  relation: main_file
file_date_updated: 2020-07-14T12:46:58Z
has_accepted_license: '1'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
page: '33'
publication_identifier:
  issn:
  - 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '523'
related_material:
  record:
  - id: '1604'
    relation: later_version
    status: public
status: public
title: Quantitative interprocedural analysis
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2016'
...
---
_id: '5449'
abstract:
- lang: eng
  text: "The fixation probability is the probability that a new mutant introduced
    in a homogeneous population eventually takes over the entire population.\r\nThe
    fixation probability is a fundamental quantity of natural selection, and known
    to depend on the population structure.\r\nAmplifiers of natural selection are
    population structures which increase the fixation probability of advantageous
    mutants, as compared to the baseline case of well-mixed populations. In this work
    we focus on symmetric population structures represented as undirected graphs.
    In the regime of undirected graphs, the strongest amplifier known has been the
    Star graph, and the existence of undirected graphs with stronger amplification
    properties has remained open for over a decade.\r\nIn this work we present the
    Comet and Comet-swarm families of undirected graphs. We show that for a range
    of fitness values of the mutants, the Comet and Comet-swarm graphs have fixation
    probability strictly larger than the fixation probability of the Star graph, for
    fixed population size and at the limit of large populations, respectively."
alternative_title:
- IST Austria Technical Report
author:
- first_name: Andreas
  full_name: Pavlogiannis, Andreas
  id: 49704004-F248-11E8-B48F-1D18A9856A87
  last_name: Pavlogiannis
  orcid: 0000-0002-8943-0722
- first_name: Josef
  full_name: Tkadlec, Josef
  id: 3F24CCC8-F248-11E8-B48F-1D18A9856A87
  last_name: Tkadlec
  orcid: 0000-0002-1097-9684
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Martin
  full_name: Nowak, Martin
  last_name: Nowak
citation:
  ama: 'Pavlogiannis A, Tkadlec J, Chatterjee K, Nowak M. <i>Amplification on Undirected
    Population Structures: Comets Beat Stars</i>. IST Austria; 2016. doi:<a href="https://doi.org/10.15479/AT:IST-2016-648-v1-1">10.15479/AT:IST-2016-648-v1-1</a>'
  apa: 'Pavlogiannis, A., Tkadlec, J., Chatterjee, K., &#38; Nowak, M. (2016). <i>Amplification
    on undirected population structures: Comets beat stars</i>. IST Austria. <a href="https://doi.org/10.15479/AT:IST-2016-648-v1-1">https://doi.org/10.15479/AT:IST-2016-648-v1-1</a>'
  chicago: 'Pavlogiannis, Andreas, Josef Tkadlec, Krishnendu Chatterjee, and Martin
    Nowak. <i>Amplification on Undirected Population Structures: Comets Beat Stars</i>.
    IST Austria, 2016. <a href="https://doi.org/10.15479/AT:IST-2016-648-v1-1">https://doi.org/10.15479/AT:IST-2016-648-v1-1</a>.'
  ieee: 'A. Pavlogiannis, J. Tkadlec, K. Chatterjee, and M. Nowak, <i>Amplification
    on undirected population structures: Comets beat stars</i>. IST Austria, 2016.'
  ista: 'Pavlogiannis A, Tkadlec J, Chatterjee K, Nowak M. 2016. Amplification on
    undirected population structures: Comets beat stars, IST Austria, 22p.'
  mla: 'Pavlogiannis, Andreas, et al. <i>Amplification on Undirected Population Structures:
    Comets Beat Stars</i>. IST Austria, 2016, doi:<a href="https://doi.org/10.15479/AT:IST-2016-648-v1-1">10.15479/AT:IST-2016-648-v1-1</a>.'
  short: 'A. Pavlogiannis, J. Tkadlec, K. Chatterjee, M. Nowak, Amplification on Undirected
    Population Structures: Comets Beat Stars, IST Austria, 2016.'
date_created: 2018-12-12T11:39:24Z
date_published: 2016-11-09T00:00:00Z
date_updated: 2023-02-23T12:22:21Z
day: '09'
ddc:
- '519'
department:
- _id: KrCh
doi: 10.15479/AT:IST-2016-648-v1-1
file:
- access_level: open_access
  checksum: 8345a8c1e7d7f0cd92516d182b7fc59e
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T11:54:07Z
  date_updated: 2020-07-14T12:46:58Z
  file_id: '5529'
  file_name: IST-2016-648-v1+1_tr.pdf
  file_size: 1264221
  relation: main_file
file_date_updated: 2020-07-14T12:46:58Z
has_accepted_license: '1'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Updated Version
page: '22'
publication_identifier:
  issn:
  - 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '648'
related_material:
  record:
  - id: '512'
    relation: later_version
    status: public
status: public
title: 'Amplification on undirected population structures: Comets beat stars'
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2016'
...
---
_id: '5451'
alternative_title:
- IST Austria Technical Report
author:
- first_name: Andreas
  full_name: Pavlogiannis, Andreas
  id: 49704004-F248-11E8-B48F-1D18A9856A87
  last_name: Pavlogiannis
  orcid: 0000-0002-8943-0722
- first_name: Josef
  full_name: Tkadlec, Josef
  id: 3F24CCC8-F248-11E8-B48F-1D18A9856A87
  last_name: Tkadlec
  orcid: 0000-0002-1097-9684
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Martin
  full_name: Nowak, Martin
  last_name: Nowak
citation:
  ama: Pavlogiannis A, Tkadlec J, Chatterjee K, Nowak M. <i>Strong Amplifiers of Natural
    Selection</i>. IST Austria; 2016. doi:<a href="https://doi.org/10.15479/AT:IST-2016-728-v1-1">10.15479/AT:IST-2016-728-v1-1</a>
  apa: Pavlogiannis, A., Tkadlec, J., Chatterjee, K., &#38; Nowak, M. (2016). <i>Strong
    amplifiers of natural selection</i>. IST Austria. <a href="https://doi.org/10.15479/AT:IST-2016-728-v1-1">https://doi.org/10.15479/AT:IST-2016-728-v1-1</a>
  chicago: Pavlogiannis, Andreas, Josef Tkadlec, Krishnendu Chatterjee, and Martin
    Nowak. <i>Strong Amplifiers of Natural Selection</i>. IST Austria, 2016. <a href="https://doi.org/10.15479/AT:IST-2016-728-v1-1">https://doi.org/10.15479/AT:IST-2016-728-v1-1</a>.
  ieee: A. Pavlogiannis, J. Tkadlec, K. Chatterjee, and M. Nowak, <i>Strong amplifiers
    of natural selection</i>. IST Austria, 2016.
  ista: Pavlogiannis A, Tkadlec J, Chatterjee K, Nowak M. 2016. Strong amplifiers
    of natural selection, IST Austria, 34p.
  mla: Pavlogiannis, Andreas, et al. <i>Strong Amplifiers of Natural Selection</i>.
    IST Austria, 2016, doi:<a href="https://doi.org/10.15479/AT:IST-2016-728-v1-1">10.15479/AT:IST-2016-728-v1-1</a>.
  short: A. Pavlogiannis, J. Tkadlec, K. Chatterjee, M. Nowak, Strong Amplifiers of
    Natural Selection, IST Austria, 2016.
date_created: 2018-12-12T11:39:24Z
date_published: 2016-12-30T00:00:00Z
date_updated: 2023-02-23T12:27:05Z
day: '30'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.15479/AT:IST-2016-728-v1-1
file:
- access_level: open_access
  checksum: 7b8bb17c322c0556acba6ac169fa71c1
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T11:53:04Z
  date_updated: 2020-07-14T12:46:59Z
  file_id: '5465'
  file_name: IST-2016-728-v1+1_main.pdf
  file_size: 1014732
  relation: main_file
file_date_updated: 2020-07-14T12:46:59Z
has_accepted_license: '1'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
page: '34'
publication_identifier:
  issn:
  - 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '728'
status: public
title: Strong amplifiers of natural selection
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2016'
...
---
_id: '5452'
alternative_title:
- IST Austria Technical Report
article_processing_charge: No
author:
- first_name: Andreas
  full_name: Pavlogiannis, Andreas
  id: 49704004-F248-11E8-B48F-1D18A9856A87
  last_name: Pavlogiannis
  orcid: 0000-0002-8943-0722
- first_name: Josef
  full_name: Tkadlec, Josef
  id: 3F24CCC8-F248-11E8-B48F-1D18A9856A87
  last_name: Tkadlec
  orcid: 0000-0002-1097-9684
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Martin
  full_name: Nowak, Martin
  last_name: Nowak
citation:
  ama: Pavlogiannis A, Tkadlec J, Chatterjee K, Nowak M. <i>Arbitrarily Strong Amplifiers
    of Natural Selection</i>. IST Austria; 2016. doi:<a href="https://doi.org/10.15479/AT:IST-2017-728-v2-1">10.15479/AT:IST-2017-728-v2-1</a>
  apa: Pavlogiannis, A., Tkadlec, J., Chatterjee, K., &#38; Nowak, M. (2016). <i>Arbitrarily
    strong amplifiers of natural selection</i>. IST Austria. <a href="https://doi.org/10.15479/AT:IST-2017-728-v2-1">https://doi.org/10.15479/AT:IST-2017-728-v2-1</a>
  chicago: Pavlogiannis, Andreas, Josef Tkadlec, Krishnendu Chatterjee, and Martin
    Nowak. <i>Arbitrarily Strong Amplifiers of Natural Selection</i>. IST Austria,
    2016. <a href="https://doi.org/10.15479/AT:IST-2017-728-v2-1">https://doi.org/10.15479/AT:IST-2017-728-v2-1</a>.
  ieee: A. Pavlogiannis, J. Tkadlec, K. Chatterjee, and M. Nowak, <i>Arbitrarily strong
    amplifiers of natural selection</i>. IST Austria, 2016.
  ista: Pavlogiannis A, Tkadlec J, Chatterjee K, Nowak M. 2016. Arbitrarily strong
    amplifiers of natural selection, IST Austria, 32p.
  mla: Pavlogiannis, Andreas, et al. <i>Arbitrarily Strong Amplifiers of Natural Selection</i>.
    IST Austria, 2016, doi:<a href="https://doi.org/10.15479/AT:IST-2017-728-v2-1">10.15479/AT:IST-2017-728-v2-1</a>.
  short: A. Pavlogiannis, J. Tkadlec, K. Chatterjee, M. Nowak, Arbitrarily Strong
    Amplifiers of Natural Selection, IST Austria, 2016.
date_created: 2018-12-12T11:39:25Z
date_published: 2016-12-30T00:00:00Z
date_updated: 2024-02-21T13:48:42Z
day: '30'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.15479/AT:IST-2017-728-v2-1
ec_funded: 1
file:
- access_level: open_access
  checksum: 58e895f26c82f560c0f0989bf8b08599
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T11:52:59Z
  date_updated: 2020-07-14T12:46:59Z
  file_id: '5460'
  file_name: IST-2017-728-v2+1_main.pdf
  file_size: 811558
  relation: main_file
file_date_updated: 2020-07-14T12:46:59Z
has_accepted_license: '1'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
page: '32'
project:
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '279307'
  name: 'Quantitative Graph Games: Theory and Applications'
publication_identifier:
  issn:
  - 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '750'
related_material:
  record:
  - id: '5453'
    relation: later_version
    status: public
  - id: '5559'
    relation: popular_science
    status: public
status: public
title: Arbitrarily strong amplifiers of natural selection
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2016'
...
---
_id: '5453'
alternative_title:
- IST Austria Technical Report
author:
- first_name: Andreas
  full_name: Pavlogiannis, Andreas
  id: 49704004-F248-11E8-B48F-1D18A9856A87
  last_name: Pavlogiannis
  orcid: 0000-0002-8943-0722
- first_name: Josef
  full_name: Tkadlec, Josef
  id: 3F24CCC8-F248-11E8-B48F-1D18A9856A87
  last_name: Tkadlec
  orcid: 0000-0002-1097-9684
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Martin
  full_name: Nowak, Martin
  last_name: Nowak
citation:
  ama: Pavlogiannis A, Tkadlec J, Chatterjee K, Nowak M. <i>Arbitrarily Strong Amplifiers
    of Natural Selection</i>. IST Austria; 2016. doi:<a href="https://doi.org/10.15479/AT:IST-2017-749-v3-1">10.15479/AT:IST-2017-749-v3-1</a>
  apa: Pavlogiannis, A., Tkadlec, J., Chatterjee, K., &#38; Nowak, M. (2016). <i>Arbitrarily
    strong amplifiers of natural selection</i>. IST Austria. <a href="https://doi.org/10.15479/AT:IST-2017-749-v3-1">https://doi.org/10.15479/AT:IST-2017-749-v3-1</a>
  chicago: Pavlogiannis, Andreas, Josef Tkadlec, Krishnendu Chatterjee, and Martin
    Nowak. <i>Arbitrarily Strong Amplifiers of Natural Selection</i>. IST Austria,
    2016. <a href="https://doi.org/10.15479/AT:IST-2017-749-v3-1">https://doi.org/10.15479/AT:IST-2017-749-v3-1</a>.
  ieee: A. Pavlogiannis, J. Tkadlec, K. Chatterjee, and M. Nowak, <i>Arbitrarily strong
    amplifiers of natural selection</i>. IST Austria, 2016.
  ista: Pavlogiannis A, Tkadlec J, Chatterjee K, Nowak M. 2016. Arbitrarily strong
    amplifiers of natural selection, IST Austria, 34p.
  mla: Pavlogiannis, Andreas, et al. <i>Arbitrarily Strong Amplifiers of Natural Selection</i>.
    IST Austria, 2016, doi:<a href="https://doi.org/10.15479/AT:IST-2017-749-v3-1">10.15479/AT:IST-2017-749-v3-1</a>.
  short: A. Pavlogiannis, J. Tkadlec, K. Chatterjee, M. Nowak, Arbitrarily Strong
    Amplifiers of Natural Selection, IST Austria, 2016.
date_created: 2018-12-12T11:39:25Z
date_published: 2016-12-30T00:00:00Z
date_updated: 2023-02-23T12:27:07Z
day: '30'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.15479/AT:IST-2017-749-v3-1
file:
- access_level: open_access
  checksum: 83b0313dab3bff4bdb6ac38695026fda
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T11:53:13Z
  date_updated: 2020-07-14T12:46:59Z
  file_id: '5474'
  file_name: IST-2017-749-v3+1_main.pdf
  file_size: 1015647
  relation: main_file
file_date_updated: 2020-07-14T12:46:59Z
has_accepted_license: '1'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
page: '34'
publication_identifier:
  issn:
  - 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '755'
related_material:
  record:
  - id: '5452'
    relation: earlier_version
    status: public
status: public
title: Arbitrarily strong amplifiers of natural selection
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2016'
...
---
_id: '5550'
abstract:
- lang: eng
  text: "We collected flower colour information on species in the tribe Antirrhineae
    from taxonomic literature. We also retreived molecular data from GenBank for as
    many of these species as possible to estimate phylogenetic relationships among
    these taxa. We then used the R package 'diversitree' to examine patterns of evolutionary
    transitions between anthocyanin and yellow pigmentation across the phylogeny.\r\n\r\nFor
    full details of the methods see:\r\nEllis TJ and Field DL \"Repeated gains in
    yellow and anthocyanin pigmentation in flower colour transitions in the Antirrhineae”,
    Annals of Botany (in press)"
article_processing_charge: No
author:
- first_name: Thomas
  full_name: Ellis, Thomas
  id: 3153D6D4-F248-11E8-B48F-1D18A9856A87
  last_name: Ellis
  orcid: 0000-0002-8511-0254
- first_name: David
  full_name: Field, David
  id: 419049E2-F248-11E8-B48F-1D18A9856A87
  last_name: Field
  orcid: 0000-0002-4014-8478
citation:
  ama: Ellis T, Field D. Flower colour data and phylogeny (NEXUS) files. 2016. doi:<a
    href="https://doi.org/10.15479/AT:ISTA:34">10.15479/AT:ISTA:34</a>
  apa: Ellis, T., &#38; Field, D. (2016). Flower colour data and phylogeny (NEXUS)
    files. Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/AT:ISTA:34">https://doi.org/10.15479/AT:ISTA:34</a>
  chicago: Ellis, Thomas, and David Field. “Flower Colour Data and Phylogeny (NEXUS)
    Files.” Institute of Science and Technology Austria, 2016. <a href="https://doi.org/10.15479/AT:ISTA:34">https://doi.org/10.15479/AT:ISTA:34</a>.
  ieee: T. Ellis and D. Field, “Flower colour data and phylogeny (NEXUS) files.” Institute
    of Science and Technology Austria, 2016.
  ista: Ellis T, Field D. 2016. Flower colour data and phylogeny (NEXUS) files, Institute
    of Science and Technology Austria, <a href="https://doi.org/10.15479/AT:ISTA:34">10.15479/AT:ISTA:34</a>.
  mla: Ellis, Thomas, and David Field. <i>Flower Colour Data and Phylogeny (NEXUS)
    Files</i>. Institute of Science and Technology Austria, 2016, doi:<a href="https://doi.org/10.15479/AT:ISTA:34">10.15479/AT:ISTA:34</a>.
  short: T. Ellis, D. Field, (2016).
datarep_id: '34'
date_created: 2018-12-12T12:31:29Z
date_published: 2016-02-19T00:00:00Z
date_updated: 2024-02-21T13:49:54Z
day: '19'
ddc:
- '576'
department:
- _id: NiBa
doi: 10.15479/AT:ISTA:34
file:
- access_level: open_access
  checksum: 950f85b80427d357bfeff09608ba02e9
  content_type: application/zip
  creator: system
  date_created: 2018-12-12T13:02:27Z
  date_updated: 2020-07-14T12:47:00Z
  file_id: '5594'
  file_name: IST-2016-34-v1+1_tellis_flower_colour_data.zip
  file_size: 4468543
  relation: main_file
file_date_updated: 2020-07-14T12:47:00Z
has_accepted_license: '1'
license: https://creativecommons.org/publicdomain/zero/1.0/
month: '02'
oa: 1
oa_version: Published Version
publisher: Institute of Science and Technology Austria
publist_id: '5828'
related_material:
  record:
  - id: '1382'
    relation: research_paper
    status: public
status: public
title: Flower colour data and phylogeny (NEXUS) files
tmp:
  image: /images/cc_0.png
  legal_code_url: https://creativecommons.org/publicdomain/zero/1.0/legalcode
  name: Creative Commons Public Domain Dedication (CC0 1.0)
  short: CC0 (1.0)
type: research_data
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2016'
...
---
_id: '5551'
abstract:
- lang: eng
  text: "Data from array experiments investigating pollinator behaviour on snapdragons
    in controlled conditions, and their effect on plant mating. Data were collected
    as part of Tom Ellis' PhD thesis , submitted February 2016.\r\n\r\nWe placed a
    total of 36 plants in a grid inside a closed organza tent, with a single hive
    of commercially bred bumblebees (Bombus hortorum). We used only the yellow-flowered
    Antirrhinum majus striatum and the magenta-flowered Antirrhinum majus pseudomajus,
    at ratios of 6:36, 12:24, 18:18, 24:12 and 30:6.\r\n\r\nAfter 24 hours to learn
    how to deal with snapdragons, I observed pollinators foraging on plants, and recorded
    the transitions between plants. Thereafter seeds on plants were allowed to develops.
    A sample of these were grown to maturity when their flower colour could be determined,
    and they were scored as yellow, magenta, or hybrid."
article_processing_charge: No
author:
- first_name: Thomas
  full_name: Ellis, Thomas
  id: 3153D6D4-F248-11E8-B48F-1D18A9856A87
  last_name: Ellis
  orcid: 0000-0002-8511-0254
citation:
  ama: Ellis T. Data on pollinator observations and offpsring phenotypes. 2016. doi:<a
    href="https://doi.org/10.15479/AT:ISTA:35">10.15479/AT:ISTA:35</a>
  apa: Ellis, T. (2016). Data on pollinator observations and offpsring phenotypes.
    Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/AT:ISTA:35">https://doi.org/10.15479/AT:ISTA:35</a>
  chicago: Ellis, Thomas. “Data on Pollinator Observations and Offpsring Phenotypes.”
    Institute of Science and Technology Austria, 2016. <a href="https://doi.org/10.15479/AT:ISTA:35">https://doi.org/10.15479/AT:ISTA:35</a>.
  ieee: T. Ellis, “Data on pollinator observations and offpsring phenotypes.” Institute
    of Science and Technology Austria, 2016.
  ista: Ellis T. 2016. Data on pollinator observations and offpsring phenotypes, Institute
    of Science and Technology Austria, <a href="https://doi.org/10.15479/AT:ISTA:35">10.15479/AT:ISTA:35</a>.
  mla: Ellis, Thomas. <i>Data on Pollinator Observations and Offpsring Phenotypes</i>.
    Institute of Science and Technology Austria, 2016, doi:<a href="https://doi.org/10.15479/AT:ISTA:35">10.15479/AT:ISTA:35</a>.
  short: T. Ellis, (2016).
contributor:
- first_name: David
  id: 419049E2-F248-11E8-B48F-1D18A9856A87
  last_name: Field
- first_name: Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
datarep_id: '35'
date_created: 2018-12-12T12:31:29Z
date_published: 2016-02-19T00:00:00Z
date_updated: 2024-02-21T13:51:27Z
day: '19'
department:
- _id: NiBa
doi: 10.15479/AT:ISTA:35
file:
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  checksum: aa3eb85d52b110cd192aa23147c4d4f3
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  creator: system
  date_created: 2018-12-12T13:05:12Z
  date_updated: 2020-07-14T12:47:01Z
  file_id: '5640'
  file_name: IST-2016-35-v1+1_array_data.zip
  file_size: 32775
  relation: main_file
file_date_updated: 2020-07-14T12:47:01Z
has_accepted_license: '1'
month: '02'
oa: 1
oa_version: Published Version
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '1398'
    relation: research_paper
    status: public
status: public
title: Data on pollinator observations and offpsring phenotypes
tmp:
  image: /images/cc_0.png
  legal_code_url: https://creativecommons.org/publicdomain/zero/1.0/legalcode
  name: Creative Commons Public Domain Dedication (CC0 1.0)
  short: CC0 (1.0)
type: research_data
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2016'
...
---
_id: '5552'
abstract:
- lang: eng
  text: "Data on pollinator visitation to wild snapdragons in a natural hybrid zone,
    collected as part of Tom Ellis' PhD thesis (submitted February 2016).\r\n\r\nSnapdragon
    flowers have a mouth-like structure which pollinators must open to access nectar.
    We placed 5mm cellophane tags in these mouths, which are held in place by the
    pressure of the flower until a pollinator visits. When she opens the flower, the
    tag drops out, and one can infer a visit. We surveyed plants over multiple days
    in 2010, 2011 and 2012.\r\n\r\nAlso included are data on phenotypic and demographic
    variables which may be explanatory variables for pollinator visitation."
article_processing_charge: No
author:
- first_name: Thomas
  full_name: Ellis, Thomas
  id: 3153D6D4-F248-11E8-B48F-1D18A9856A87
  last_name: Ellis
  orcid: 0000-0002-8511-0254
citation:
  ama: Ellis T. Pollinator visitation data for wild Antirrhinum majus plants, with
    phenotypic and frequency data. 2016. doi:<a href="https://doi.org/10.15479/AT:ISTA:36">10.15479/AT:ISTA:36</a>
  apa: Ellis, T. (2016). Pollinator visitation data for wild Antirrhinum majus plants,
    with phenotypic and frequency data. Institute of Science and Technology Austria.
    <a href="https://doi.org/10.15479/AT:ISTA:36">https://doi.org/10.15479/AT:ISTA:36</a>
  chicago: Ellis, Thomas. “Pollinator Visitation Data for Wild Antirrhinum Majus Plants,
    with Phenotypic and Frequency Data.” Institute of Science and Technology Austria,
    2016. <a href="https://doi.org/10.15479/AT:ISTA:36">https://doi.org/10.15479/AT:ISTA:36</a>.
  ieee: T. Ellis, “Pollinator visitation data for wild Antirrhinum majus plants, with
    phenotypic and frequency data.” Institute of Science and Technology Austria, 2016.
  ista: Ellis T. 2016. Pollinator visitation data for wild Antirrhinum majus plants,
    with phenotypic and frequency data., Institute of Science and Technology Austria,
    <a href="https://doi.org/10.15479/AT:ISTA:36">10.15479/AT:ISTA:36</a>.
  mla: Ellis, Thomas. <i>Pollinator Visitation Data for Wild Antirrhinum Majus Plants,
    with Phenotypic and Frequency Data.</i> Institute of Science and Technology Austria,
    2016, doi:<a href="https://doi.org/10.15479/AT:ISTA:36">10.15479/AT:ISTA:36</a>.
  short: T. Ellis, (2016).
contributor:
- first_name: David
  id: 419049E2-F248-11E8-B48F-1D18A9856A87
  last_name: Field
- first_name: Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
datarep_id: '36'
date_created: 2018-12-12T12:31:30Z
date_published: 2016-02-19T00:00:00Z
date_updated: 2024-02-21T13:51:40Z
day: '19'
department:
- _id: NiBa
doi: 10.15479/AT:ISTA:36
file:
- access_level: open_access
  checksum: cbc61b523d4d475a04a737d50dc470ef
  content_type: application/zip
  creator: system
  date_created: 2018-12-12T13:03:07Z
  date_updated: 2020-07-14T12:47:01Z
  file_id: '5625'
  file_name: IST-2016-36-v1+1_tag_assay_archive.zip
  file_size: 44905
  relation: main_file
file_date_updated: 2020-07-14T12:47:01Z
has_accepted_license: '1'
month: '02'
oa: 1
oa_version: Published Version
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '1398'
    relation: research_paper
    status: public
status: public
title: Pollinator visitation data for wild Antirrhinum majus plants, with phenotypic
  and frequency data.
type: research_data
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2016'
...
---
_id: '5553'
abstract:
- lang: eng
  text: "Genotypic, phenotypic and demographic data for 2128 wild snapdragons and
    1127 open-pollinated progeny from a natural hybrid zone, collected as part of
    Tom Ellis' PhD thesis (submitted) February 2016).\r\n\r\nTissue samples were sent
    to LGC Genomics in Berlin for DNA extraction, and genotyping at 70 SNP markers
    by KASPR genotyping. 29 of these SNPs failed to amplify reliably, and have been
    removed from this dataset.\r\n\r\nOther data were retreived from an online database
    of this population at www.antspec.org."
article_processing_charge: No
author:
- first_name: David
  full_name: Field, David
  id: 419049E2-F248-11E8-B48F-1D18A9856A87
  last_name: Field
  orcid: 0000-0002-4014-8478
- first_name: Thomas
  full_name: Ellis, Thomas
  id: 3153D6D4-F248-11E8-B48F-1D18A9856A87
  last_name: Ellis
  orcid: 0000-0002-8511-0254
citation:
  ama: Field D, Ellis T. Inference of mating patterns among wild snapdragons in a
    natural hybrid zone in 2012. 2016. doi:<a href="https://doi.org/10.15479/AT:ISTA:37">10.15479/AT:ISTA:37</a>
  apa: Field, D., &#38; Ellis, T. (2016). Inference of mating patterns among wild
    snapdragons in a natural hybrid zone in 2012. Institute of Science and Technology
    Austria. <a href="https://doi.org/10.15479/AT:ISTA:37">https://doi.org/10.15479/AT:ISTA:37</a>
  chicago: Field, David, and Thomas Ellis. “Inference of Mating Patterns among Wild
    Snapdragons in a Natural Hybrid Zone in 2012.” Institute of Science and Technology
    Austria, 2016. <a href="https://doi.org/10.15479/AT:ISTA:37">https://doi.org/10.15479/AT:ISTA:37</a>.
  ieee: D. Field and T. Ellis, “Inference of mating patterns among wild snapdragons
    in a natural hybrid zone in 2012.” Institute of Science and Technology Austria,
    2016.
  ista: Field D, Ellis T. 2016. Inference of mating patterns among wild snapdragons
    in a natural hybrid zone in 2012, Institute of Science and Technology Austria,
    <a href="https://doi.org/10.15479/AT:ISTA:37">10.15479/AT:ISTA:37</a>.
  mla: Field, David, and Thomas Ellis. <i>Inference of Mating Patterns among Wild
    Snapdragons in a Natural Hybrid Zone in 2012</i>. Institute of Science and Technology
    Austria, 2016, doi:<a href="https://doi.org/10.15479/AT:ISTA:37">10.15479/AT:ISTA:37</a>.
  short: D. Field, T. Ellis, (2016).
contributor:
- contributor_type: project_manager
  first_name: Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
datarep_id: '37'
date_created: 2018-12-12T12:31:30Z
date_published: 2016-02-19T00:00:00Z
date_updated: 2024-02-21T13:51:14Z
day: '19'
ddc:
- '576'
department:
- _id: NiBa
doi: 10.15479/AT:ISTA:37
file:
- access_level: open_access
  checksum: 4ae751b1fa4897fa216241f975a57313
  content_type: application/zip
  creator: system
  date_created: 2018-12-12T13:03:02Z
  date_updated: 2020-07-14T12:47:01Z
  file_id: '5620'
  file_name: IST-2016-37-v1+1_paternity_archive.zip
  file_size: 132808
  relation: main_file
file_date_updated: 2020-07-14T12:47:01Z
has_accepted_license: '1'
keyword:
- paternity assignment
- pedigree
- matting patterns
- assortative mating
- Antirrhinum majus
- frequency-dependent selection
- plant-pollinator interaction
month: '02'
oa: 1
oa_version: Published Version
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '1398'
    relation: research_paper
    status: public
status: public
title: Inference of mating patterns among wild snapdragons in a natural hybrid zone
  in 2012
tmp:
  image: /images/cc_0.png
  legal_code_url: https://creativecommons.org/publicdomain/zero/1.0/legalcode
  name: Creative Commons Public Domain Dedication (CC0 1.0)
  short: CC0 (1.0)
type: research_data
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2016'
...
---
_id: '5554'
abstract:
- lang: eng
  text: "The data stored here is used in Murat Tugrul's PhD thesis (Chapter 3), which
    is related to the evolution of bacterial RNA polymerase binding.\r\nMagdalena
    Steinrueck (PhD Student in Calin Guet's group at IST Austria) performed the experiments
    and created the data on de novo promoter evolution. Fabienne Jesse (PhD Student
    in Jon Bollback's group at IST Austria) performed the experiments and created
    the data on lac promoter evolution."
article_processing_charge: No
author:
- first_name: Murat
  full_name: Tugrul, Murat
  id: 37C323C6-F248-11E8-B48F-1D18A9856A87
  last_name: Tugrul
  orcid: 0000-0002-8523-0758
citation:
  ama: Tugrul M. Experimental Data for Binding Site Evolution of Bacterial RNA Polymerase.
    2016. doi:<a href="https://doi.org/10.15479/AT:ISTA:43">10.15479/AT:ISTA:43</a>
  apa: Tugrul, M. (2016). Experimental Data for Binding Site Evolution of Bacterial
    RNA Polymerase. Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/AT:ISTA:43">https://doi.org/10.15479/AT:ISTA:43</a>
  chicago: Tugrul, Murat. “Experimental Data for Binding Site Evolution of Bacterial
    RNA Polymerase.” Institute of Science and Technology Austria, 2016. <a href="https://doi.org/10.15479/AT:ISTA:43">https://doi.org/10.15479/AT:ISTA:43</a>.
  ieee: M. Tugrul, “Experimental Data for Binding Site Evolution of Bacterial RNA
    Polymerase.” Institute of Science and Technology Austria, 2016.
  ista: Tugrul M. 2016. Experimental Data for Binding Site Evolution of Bacterial
    RNA Polymerase, Institute of Science and Technology Austria, <a href="https://doi.org/10.15479/AT:ISTA:43">10.15479/AT:ISTA:43</a>.
  mla: Tugrul, Murat. <i>Experimental Data for Binding Site Evolution of Bacterial
    RNA Polymerase</i>. Institute of Science and Technology Austria, 2016, doi:<a
    href="https://doi.org/10.15479/AT:ISTA:43">10.15479/AT:ISTA:43</a>.
  short: M. Tugrul, (2016).
contributor:
- contributor_type: researcher
  first_name: Magdalena
  id: 2C023F40-F248-11E8-B48F-1D18A9856A87
  last_name: Steinrück
- contributor_type: researcher
  first_name: Fabienne
  id: 4C8C26A4-F248-11E8-B48F-1D18A9856A87
  last_name: Jesse
datarep_id: '43'
date_created: 2018-12-12T12:31:30Z
date_published: 2016-05-12T00:00:00Z
date_updated: 2024-02-21T13:50:34Z
day: '12'
department:
- _id: NiBa
- _id: JoBo
doi: 10.15479/AT:ISTA:43
file:
- access_level: open_access
  checksum: 1fc0a10bb7ce110fcb5e1fbe3cf0c4e2
  content_type: application/zip
  creator: system
  date_created: 2018-12-12T13:03:08Z
  date_updated: 2020-07-14T12:47:01Z
  file_id: '5626'
  file_name: IST-2016-43-v1+1_DATA_MTugrul_PhDThesis_Chapter3.zip
  file_size: 1123495
  relation: main_file
file_date_updated: 2020-07-14T12:47:01Z
has_accepted_license: '1'
keyword:
- RNAP binding
- de novo promoter evolution
- lac promoter
month: '05'
oa: 1
oa_version: Published Version
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '1131'
    relation: used_in_publication
    status: public
status: public
title: Experimental Data for Binding Site Evolution of Bacterial RNA Polymerase
tmp:
  image: /images/cc_0.png
  legal_code_url: https://creativecommons.org/publicdomain/zero/1.0/legalcode
  name: Creative Commons Public Domain Dedication (CC0 1.0)
  short: CC0 (1.0)
type: research_data
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2016'
...
---
_id: '5556'
abstract:
- lang: eng
  text: "MATLAB code and processed datasets available for reproducing the results
    in: \r\nLukačišin, M.*, Landon, M.*, Jajoo, R*. (2016) Sequence-Specific Thermodynamic
    Properties of Nucleic Acids Influence Both Transcriptional Pausing and Backtracking
    in Yeast.\r\n*equal contributions"
article_processing_charge: No
author:
- first_name: Martin
  full_name: Lukacisin, Martin
  id: 298FFE8C-F248-11E8-B48F-1D18A9856A87
  last_name: Lukacisin
  orcid: 0000-0001-6549-4177
- first_name: Matthieu
  full_name: Landon, Matthieu
  last_name: Landon
- first_name: Rishi
  full_name: Jajoo, Rishi
  last_name: Jajoo
citation:
  ama: Lukacisin M, Landon M, Jajoo R. MATLAB analysis code for “Sequence-Specific
    Thermodynamic Properties of Nucleic Acids Influence Both Transcriptional Pausing
    and Backtracking in Yeast.” 2016. doi:<a href="https://doi.org/10.15479/AT:ISTA:45">10.15479/AT:ISTA:45</a>
  apa: Lukacisin, M., Landon, M., &#38; Jajoo, R. (2016). MATLAB analysis code for
    “Sequence-Specific Thermodynamic Properties of Nucleic Acids Influence Both Transcriptional
    Pausing and Backtracking in Yeast.” Institute of Science and Technology Austria.
    <a href="https://doi.org/10.15479/AT:ISTA:45">https://doi.org/10.15479/AT:ISTA:45</a>
  chicago: Lukacisin, Martin, Matthieu Landon, and Rishi Jajoo. “MATLAB Analysis Code
    for ‘Sequence-Specific Thermodynamic Properties of Nucleic Acids Influence Both
    Transcriptional Pausing and Backtracking in Yeast.’” Institute of Science and
    Technology Austria, 2016. <a href="https://doi.org/10.15479/AT:ISTA:45">https://doi.org/10.15479/AT:ISTA:45</a>.
  ieee: M. Lukacisin, M. Landon, and R. Jajoo, “MATLAB analysis code for ‘Sequence-Specific
    Thermodynamic Properties of Nucleic Acids Influence Both Transcriptional Pausing
    and Backtracking in Yeast.’” Institute of Science and Technology Austria, 2016.
  ista: Lukacisin M, Landon M, Jajoo R. 2016. MATLAB analysis code for ‘Sequence-Specific
    Thermodynamic Properties of Nucleic Acids Influence Both Transcriptional Pausing
    and Backtracking in Yeast’, Institute of Science and Technology Austria, <a href="https://doi.org/10.15479/AT:ISTA:45">10.15479/AT:ISTA:45</a>.
  mla: Lukacisin, Martin, et al. <i>MATLAB Analysis Code for “Sequence-Specific Thermodynamic
    Properties of Nucleic Acids Influence Both Transcriptional Pausing and Backtracking
    in Yeast.”</i> Institute of Science and Technology Austria, 2016, doi:<a href="https://doi.org/10.15479/AT:ISTA:45">10.15479/AT:ISTA:45</a>.
  short: M. Lukacisin, M. Landon, R. Jajoo, (2016).
datarep_id: '45'
date_created: 2018-12-12T12:31:31Z
date_published: 2016-08-25T00:00:00Z
date_updated: 2024-02-21T13:51:53Z
day: '25'
ddc:
- '571'
department:
- _id: ToBo
doi: 10.15479/AT:ISTA:45
file:
- access_level: open_access
  checksum: ee697f2b1ade4dc14d6ac0334dd832ab
  content_type: application/zip
  creator: system
  date_created: 2018-12-12T13:02:58Z
  date_updated: 2020-07-14T12:47:02Z
  file_id: '5616'
  file_name: IST-2016-45-v1+1_PaperCode.zip
  file_size: 296722548
  relation: main_file
file_date_updated: 2020-07-14T12:47:02Z
has_accepted_license: '1'
keyword:
- transcription
- pausing
- backtracking
- polymerase
- RNA
- NET-seq
- nucleosome
- basepairing
license: https://creativecommons.org/licenses/by-sa/4.0/
month: '08'
oa: 1
oa_version: Published Version
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '8431'
    relation: used_in_publication
    status: deleted
  - id: '1029'
    relation: research_paper
    status: public
status: public
title: MATLAB analysis code for 'Sequence-Specific Thermodynamic Properties of Nucleic
  Acids Influence Both Transcriptional Pausing and Backtracking in Yeast'
tmp:
  image: /images/cc_by_sa.png
  legal_code_url: https://creativecommons.org/licenses/by-sa/4.0/legalcode
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    BY-SA 4.0)
  short: CC BY-SA (4.0)
type: research_data
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2016'
...
---
_id: '5557'
abstract:
- lang: eng
  text: "Small synthetic discrete tomography problems.\r\nSizes are 32x32, 64z64 and
    256x256.\r\nProjection angles are 2, 4, and 6.\r\nNumber of labels are 3 and 5."
article_processing_charge: No
author:
- first_name: Paul
  full_name: Swoboda, Paul
  id: 446560C6-F248-11E8-B48F-1D18A9856A87
  last_name: Swoboda
citation:
  ama: Swoboda P. Synthetic discrete tomography problems. 2016. doi:<a href="https://doi.org/10.15479/AT:ISTA:46">10.15479/AT:ISTA:46</a>
  apa: Swoboda, P. (2016). Synthetic discrete tomography problems. Institute of Science
    and Technology Austria. <a href="https://doi.org/10.15479/AT:ISTA:46">https://doi.org/10.15479/AT:ISTA:46</a>
  chicago: Swoboda, Paul. “Synthetic Discrete Tomography Problems.” Institute of Science
    and Technology Austria, 2016. <a href="https://doi.org/10.15479/AT:ISTA:46">https://doi.org/10.15479/AT:ISTA:46</a>.
  ieee: P. Swoboda, “Synthetic discrete tomography problems.” Institute of Science
    and Technology Austria, 2016.
  ista: Swoboda P. 2016. Synthetic discrete tomography problems, Institute of Science
    and Technology Austria, <a href="https://doi.org/10.15479/AT:ISTA:46">10.15479/AT:ISTA:46</a>.
  mla: Swoboda, Paul. <i>Synthetic Discrete Tomography Problems</i>. Institute of
    Science and Technology Austria, 2016, doi:<a href="https://doi.org/10.15479/AT:ISTA:46">10.15479/AT:ISTA:46</a>.
  short: P. Swoboda, (2016).
contributor:
- contributor_type: data_collector
  first_name: Jan
  last_name: Kuske
datarep_id: '46'
date_created: 2018-12-12T12:31:31Z
date_published: 2016-09-20T00:00:00Z
date_updated: 2024-02-21T13:50:21Z
day: '20'
ddc:
- '006'
department:
- _id: VlKo
doi: 10.15479/AT:ISTA:46
file:
- access_level: open_access
  checksum: aa5a16a0dc888da7186fb8fc45e88439
  content_type: application/zip
  creator: system
  date_created: 2018-12-12T13:05:19Z
  date_updated: 2020-07-14T12:47:02Z
  file_id: '5645'
  file_name: IST-2016-46-v1+1_discrete_tomography_synthetic.zip
  file_size: 36058401
  relation: main_file
file_date_updated: 2020-07-14T12:47:02Z
has_accepted_license: '1'
keyword:
- discrete tomography
month: '09'
oa: 1
oa_version: Published Version
publisher: Institute of Science and Technology Austria
status: public
title: Synthetic discrete tomography problems
tmp:
  image: /images/cc_0.png
  legal_code_url: https://creativecommons.org/publicdomain/zero/1.0/legalcode
  name: Creative Commons Public Domain Dedication (CC0 1.0)
  short: CC0 (1.0)
type: research_data
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2016'
...
---
_id: '5558'
abstract:
- lang: eng
  text: PhD thesis LaTeX source code
article_processing_charge: No
author:
- first_name: Morten
  full_name: Bojsen-Hansen, Morten
  id: 439F0C8C-F248-11E8-B48F-1D18A9856A87
  last_name: Bojsen-Hansen
  orcid: 0000-0002-4417-3224
citation:
  ama: Bojsen-Hansen M. Tracking, Correcting and Absorbing Water Surface Waves. 2016.
    doi:<a href="https://doi.org/10.15479/AT:ISTA:48">10.15479/AT:ISTA:48</a>
  apa: Bojsen-Hansen, M. (2016). Tracking, Correcting and Absorbing Water Surface
    Waves. Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/AT:ISTA:48">https://doi.org/10.15479/AT:ISTA:48</a>
  chicago: Bojsen-Hansen, Morten. “Tracking, Correcting and Absorbing Water Surface
    Waves.” Institute of Science and Technology Austria, 2016. <a href="https://doi.org/10.15479/AT:ISTA:48">https://doi.org/10.15479/AT:ISTA:48</a>.
  ieee: M. Bojsen-Hansen, “Tracking, Correcting and Absorbing Water Surface Waves.”
    Institute of Science and Technology Austria, 2016.
  ista: Bojsen-Hansen M. 2016. Tracking, Correcting and Absorbing Water Surface Waves,
    Institute of Science and Technology Austria, <a href="https://doi.org/10.15479/AT:ISTA:48">10.15479/AT:ISTA:48</a>.
  mla: Bojsen-Hansen, Morten. <i>Tracking, Correcting and Absorbing Water Surface
    Waves</i>. Institute of Science and Technology Austria, 2016, doi:<a href="https://doi.org/10.15479/AT:ISTA:48">10.15479/AT:ISTA:48</a>.
  short: M. Bojsen-Hansen, (2016).
datarep_id: '48'
date_created: 2018-12-12T12:31:31Z
date_published: 2016-09-23T00:00:00Z
date_updated: 2024-02-21T13:50:48Z
day: '23'
ddc:
- '004'
department:
- _id: ChWo
doi: 10.15479/AT:ISTA:48
file:
- access_level: open_access
  checksum: 5b1b256ad796fbddb4b7729f5e45e444
  content_type: application/x-bzip2
  creator: system
  date_created: 2018-12-12T13:02:18Z
  date_updated: 2020-07-14T12:47:02Z
  file_id: '5589'
  file_name: IST-2016-48-v1+1_2016_Bojsen-Hansen_TCaAWSW.tar.bz2
  file_size: 55237885
  relation: main_file
file_date_updated: 2020-07-14T12:47:02Z
has_accepted_license: '1'
month: '09'
oa: 1
oa_version: Published Version
publisher: Institute of Science and Technology Austria
publist_id: '6238'
pubrep_id: '640'
related_material:
  record:
  - id: '1122'
    relation: other
    status: public
status: public
title: Tracking, Correcting and Absorbing Water Surface Waves
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: research_data
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2016'
...
---
_id: '5749'
abstract:
- lang: eng
  text: Parasitism creates selection for resistance mechanisms in host populations
    and is hypothesized to promote increased host evolvability. However, the influence
    of these traits on host evolution when parasites are no longer present is unclear.
    We used experimental evolution and whole-genome sequencing of Escherichia coli
    to determine the effects of past and present exposure to parasitic viruses (phages)
    on the spread of mutator alleles, resistance, and bacterial competitive fitness.
    We found that mutator alleles spread rapidly during adaptation to any of four
    different phage species, and this pattern was even more pronounced with multiple
    phages present simultaneously. However, hypermutability did not detectably accelerate
    adaptation in the absence of phages and recovery of fitness costs associated with
    resistance. Several lineages evolved phage resistance through elevated mucoidy,
    and during subsequent evolution in phage-free conditions they rapidly reverted
    to nonmucoid, phage-susceptible phenotypes. Genome sequencing revealed that this
    phenotypic reversion was achieved by additional genetic changes rather than by
    genotypic reversion of the initial resistance mutations. Insertion sequence (IS)
    elements played a key role in both the acquisition of resistance and adaptation
    in the absence of parasites; unlike single nucleotide polymorphisms, IS insertions
    were not more frequent in mutator lineages. Our results provide a genetic explanation
    for rapid reversion of mucoidy, a phenotype observed in other bacterial species
    including human pathogens. Moreover, this demonstrates that the types of genetic
    change underlying adaptation to fitness costs, and consequently the impact of
    evolvability mechanisms such as increased point-mutation rates, depend critically
    on the mechanism of resistance.
acknowledgement: The authors thank three anonymous reviewers and the editor for helpful
  comments on the manuscript, as well as Dominique Schneider for feedback on an earlier
  draft, Jenna Gallie for lytic λ and Julien Capelle for T5 and T6. This work was
  supported by the Swiss National Science Foundation (PZ00P3_148255 to A.H.) and an
  EU Marie Curie PEOPLE Postdoctoral Fellowship for Career Development (FP7-PEOPLE-2012-IEF-331824
  to S.W.).
article_processing_charge: No
author:
- first_name: Sébastien
  full_name: Wielgoss, Sébastien
  last_name: Wielgoss
- first_name: Tobias
  full_name: Bergmiller, Tobias
  id: 2C471CFA-F248-11E8-B48F-1D18A9856A87
  last_name: Bergmiller
  orcid: 0000-0001-5396-4346
- first_name: Anna M.
  full_name: Bischofberger, Anna M.
  last_name: Bischofberger
- first_name: Alex R.
  full_name: Hall, Alex R.
  last_name: Hall
citation:
  ama: Wielgoss S, Bergmiller T, Bischofberger AM, Hall AR. Adaptation to parasites
    and costs of parasite resistance in mutator and nonmutator bacteria. <i>Molecular
    Biology and Evolution</i>. 2016;33(3):770-782. doi:<a href="https://doi.org/10.1093/molbev/msv270">10.1093/molbev/msv270</a>
  apa: Wielgoss, S., Bergmiller, T., Bischofberger, A. M., &#38; Hall, A. R. (2016).
    Adaptation to parasites and costs of parasite resistance in mutator and nonmutator
    bacteria. <i>Molecular Biology and Evolution</i>. Oxford University Press. <a
    href="https://doi.org/10.1093/molbev/msv270">https://doi.org/10.1093/molbev/msv270</a>
  chicago: Wielgoss, Sébastien, Tobias Bergmiller, Anna M. Bischofberger, and Alex
    R. Hall. “Adaptation to Parasites and Costs of Parasite Resistance in Mutator
    and Nonmutator Bacteria.” <i>Molecular Biology and Evolution</i>. Oxford University
    Press, 2016. <a href="https://doi.org/10.1093/molbev/msv270">https://doi.org/10.1093/molbev/msv270</a>.
  ieee: S. Wielgoss, T. Bergmiller, A. M. Bischofberger, and A. R. Hall, “Adaptation
    to parasites and costs of parasite resistance in mutator and nonmutator bacteria,”
    <i>Molecular Biology and Evolution</i>, vol. 33, no. 3. Oxford University Press,
    pp. 770–782, 2016.
  ista: Wielgoss S, Bergmiller T, Bischofberger AM, Hall AR. 2016. Adaptation to parasites
    and costs of parasite resistance in mutator and nonmutator bacteria. Molecular
    Biology and Evolution. 33(3), 770–782.
  mla: Wielgoss, Sébastien, et al. “Adaptation to Parasites and Costs of Parasite
    Resistance in Mutator and Nonmutator Bacteria.” <i>Molecular Biology and Evolution</i>,
    vol. 33, no. 3, Oxford University Press, 2016, pp. 770–82, doi:<a href="https://doi.org/10.1093/molbev/msv270">10.1093/molbev/msv270</a>.
  short: S. Wielgoss, T. Bergmiller, A.M. Bischofberger, A.R. Hall, Molecular Biology
    and Evolution 33 (2016) 770–782.
date_created: 2018-12-18T13:18:10Z
date_published: 2016-03-01T00:00:00Z
date_updated: 2023-09-05T13:46:05Z
day: '01'
ddc:
- '576'
department:
- _id: CaGu
doi: 10.1093/molbev/msv270
external_id:
  pmid:
  - '26609077'
file:
- access_level: open_access
  checksum: 47d9010690b6c5c17f2ac830cc63ac5c
  content_type: application/pdf
  creator: dernst
  date_created: 2018-12-18T13:21:45Z
  date_updated: 2020-07-14T12:47:10Z
  file_id: '5750'
  file_name: 2016_MolBiolEvol_Wielgoss.pdf
  file_size: 634037
  relation: main_file
file_date_updated: 2020-07-14T12:47:10Z
has_accepted_license: '1'
intvolume: '        33'
issue: '3'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
page: 770-782
pmid: 1
publication: Molecular Biology and Evolution
publication_identifier:
  eissn:
  - 1537-1719
  issn:
  - 0737-4038
publication_status: published
publisher: Oxford University Press
pubrep_id: '587'
quality_controlled: '1'
related_material:
  record:
  - id: '9719'
    relation: research_data
    status: public
scopus_import: '1'
status: public
title: Adaptation to parasites and costs of parasite resistance in mutator and nonmutator
  bacteria
tmp:
  image: /images/cc_by_nc.png
  legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
  short: CC BY-NC (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 33
year: '2016'
...
---
_id: '5805'
abstract:
- lang: eng
  text: Discretization of sphere in the integer space follows a particular discretization
    scheme, which, in principle, conforms to some topological model. This eventually
    gives rise to interesting topological properties of a discrete spherical surface,
    which need to be investigated for its analytical characterization. This paper
    presents some novel results on the local topological properties of the naive model
    of discrete sphere. They follow from the bijection of each quadraginta octant
    of naive sphere with its projection map called f -map on the corresponding functional
    plane and from the characterization of certain jumps in the f-map. As an application,
    we have shown how these properties can be used in designing an efficient reconstruction
    algorithm for a naive spherical surface from an input voxel set when it is sparse
    or noisy.
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Nabhasmita
  full_name: Sen, Nabhasmita
  last_name: Sen
- first_name: Ranita
  full_name: Biswas, Ranita
  id: 3C2B033E-F248-11E8-B48F-1D18A9856A87
  last_name: Biswas
  orcid: 0000-0002-5372-7890
- first_name: Partha
  full_name: Bhowmick, Partha
  last_name: Bhowmick
citation:
  ama: 'Sen N, Biswas R, Bhowmick P. On some local topological properties of naive
    discrete sphere. In: <i>Computational Topology in Image Context</i>. Vol 9667.
    Cham: Springer Nature; 2016:253-264. doi:<a href="https://doi.org/10.1007/978-3-319-39441-1_23">10.1007/978-3-319-39441-1_23</a>'
  apa: 'Sen, N., Biswas, R., &#38; Bhowmick, P. (2016). On some local topological
    properties of naive discrete sphere. In <i>Computational Topology in Image Context</i>
    (Vol. 9667, pp. 253–264). Cham: Springer Nature. <a href="https://doi.org/10.1007/978-3-319-39441-1_23">https://doi.org/10.1007/978-3-319-39441-1_23</a>'
  chicago: 'Sen, Nabhasmita, Ranita Biswas, and Partha Bhowmick. “On Some Local Topological
    Properties of Naive Discrete Sphere.” In <i>Computational Topology in Image Context</i>,
    9667:253–64. Cham: Springer Nature, 2016. <a href="https://doi.org/10.1007/978-3-319-39441-1_23">https://doi.org/10.1007/978-3-319-39441-1_23</a>.'
  ieee: 'N. Sen, R. Biswas, and P. Bhowmick, “On some local topological properties
    of naive discrete sphere,” in <i>Computational Topology in Image Context</i>,
    vol. 9667, Cham: Springer Nature, 2016, pp. 253–264.'
  ista: 'Sen N, Biswas R, Bhowmick P. 2016.On some local topological properties of
    naive discrete sphere. In: Computational Topology in Image Context. LNCS, vol.
    9667, 253–264.'
  mla: Sen, Nabhasmita, et al. “On Some Local Topological Properties of Naive Discrete
    Sphere.” <i>Computational Topology in Image Context</i>, vol. 9667, Springer Nature,
    2016, pp. 253–64, doi:<a href="https://doi.org/10.1007/978-3-319-39441-1_23">10.1007/978-3-319-39441-1_23</a>.
  short: N. Sen, R. Biswas, P. Bhowmick, in:, Computational Topology in Image Context,
    Springer Nature, Cham, 2016, pp. 253–264.
conference:
  end_date: 2016-06-17
  location: Marseille, France
  name: 'CTIC: Computational Topology in Image Context'
  start_date: 2016-06-15
date_created: 2019-01-08T20:44:24Z
date_published: 2016-06-02T00:00:00Z
date_updated: 2022-01-28T08:01:22Z
day: '02'
department:
- _id: HeEd
doi: 10.1007/978-3-319-39441-1_23
extern: '1'
intvolume: '      9667'
language:
- iso: eng
month: '06'
oa_version: None
page: 253-264
place: Cham
publication: Computational Topology in Image Context
publication_identifier:
  eisbn:
  - 978-3-319-39441-1
  eissn:
  - 1611-3349
  isbn:
  - 978-3-319-39440-4
  issn:
  - 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: On some local topological properties of naive discrete sphere
type: book_chapter
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 9667
year: '2016'
...
---
_id: '5806'
abstract:
- lang: eng
  text: Although the concept of functional plane for naive plane is studied and reported
    in the literature in great detail, no similar study is yet found for naive sphere.
    This article exposes the first study in this line, opening up further prospects
    of analyzing the topological properties of sphere in the discrete space. We show
    that each quadraginta octant Q of a naive sphere forms a bijection with its projected
    pixel set on a unique coordinate plane, which thereby serves as the functional
    plane of Q, and hence gives rise to merely mono-jumps during back projection.
    The other two coordinate planes serve as para-functional and dia-functional planes
    for Q, as the former is ‘mono-jumping’ but not bijective, whereas the latter holds
    neither of the two. Owing to this, the quadraginta octants form symmetry groups
    and subgroups with equivalent jump conditions. We also show a potential application
    in generating a special class of discrete 3D circles based on back projection
    and jump bridging by Steiner voxels. A circle in this class possesses 4-symmetry,
    uniqueness, and bounded distance from the underlying real sphere and real plane.
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Ranita
  full_name: Biswas, Ranita
  id: 3C2B033E-F248-11E8-B48F-1D18A9856A87
  last_name: Biswas
  orcid: 0000-0002-5372-7890
- first_name: Partha
  full_name: Bhowmick, Partha
  last_name: Bhowmick
citation:
  ama: 'Biswas R, Bhowmick P. On functionality of quadraginta octants of naive sphere
    with application to circle drawing. In: <i>Discrete Geometry for Computer Imagery</i>.
    Vol 9647. Cham: Springer Nature; 2016:256-267. doi:<a href="https://doi.org/10.1007/978-3-319-32360-2_20">10.1007/978-3-319-32360-2_20</a>'
  apa: 'Biswas, R., &#38; Bhowmick, P. (2016). On functionality of quadraginta octants
    of naive sphere with application to circle drawing. In <i>Discrete Geometry for
    Computer Imagery</i> (Vol. 9647, pp. 256–267). Cham: Springer Nature. <a href="https://doi.org/10.1007/978-3-319-32360-2_20">https://doi.org/10.1007/978-3-319-32360-2_20</a>'
  chicago: 'Biswas, Ranita, and Partha Bhowmick. “On Functionality of Quadraginta
    Octants of Naive Sphere with Application to Circle Drawing.” In <i>Discrete Geometry
    for Computer Imagery</i>, 9647:256–67. Cham: Springer Nature, 2016. <a href="https://doi.org/10.1007/978-3-319-32360-2_20">https://doi.org/10.1007/978-3-319-32360-2_20</a>.'
  ieee: R. Biswas and P. Bhowmick, “On functionality of quadraginta octants of naive
    sphere with application to circle drawing,” in <i>Discrete Geometry for Computer
    Imagery</i>, Nantes, France, 2016, vol. 9647, pp. 256–267.
  ista: 'Biswas R, Bhowmick P. 2016. On functionality of quadraginta octants of naive
    sphere with application to circle drawing. Discrete Geometry for Computer Imagery.
    DGCI: International Conference on Discrete Geometry for Computer Imagery, LNCS,
    vol. 9647, 256–267.'
  mla: Biswas, Ranita, and Partha Bhowmick. “On Functionality of Quadraginta Octants
    of Naive Sphere with Application to Circle Drawing.” <i>Discrete Geometry for
    Computer Imagery</i>, vol. 9647, Springer Nature, 2016, pp. 256–67, doi:<a href="https://doi.org/10.1007/978-3-319-32360-2_20">10.1007/978-3-319-32360-2_20</a>.
  short: R. Biswas, P. Bhowmick, in:, Discrete Geometry for Computer Imagery, Springer
    Nature, Cham, 2016, pp. 256–267.
conference:
  end_date: 2016-04-20
  location: Nantes, France
  name: 'DGCI: International Conference on Discrete Geometry for Computer Imagery'
  start_date: 2016-04-18
date_created: 2019-01-08T20:44:37Z
date_published: 2016-04-09T00:00:00Z
date_updated: 2022-01-28T08:10:11Z
day: '09'
department:
- _id: HeEd
doi: 10.1007/978-3-319-32360-2_20
extern: '1'
intvolume: '      9647'
language:
- iso: eng
month: '04'
oa_version: None
page: 256-267
place: Cham
publication: Discrete Geometry for Computer Imagery
publication_identifier:
  eisbn:
  - 978-3-319-32360-2
  isbn:
  - 978-3-319-32359-6
  issn:
  - 0302-9743
  - 1611-3349
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: On functionality of quadraginta octants of naive sphere with application to
  circle drawing
type: conference
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 9647
year: '2016'
...
