---
_id: '9776'
article_processing_charge: No
author:
- first_name: Rok
  full_name: Grah, Rok
  id: 483E70DE-F248-11E8-B48F-1D18A9856A87
  last_name: Grah
  orcid: 0000-0003-2539-3560
- first_name: Tamar
  full_name: Friedlander, Tamar
  last_name: Friedlander
citation:
  ama: Grah R, Friedlander T. Supporting information. 2020. doi:<a href="https://doi.org/10.1371/journal.pcbi.1007642.s001">10.1371/journal.pcbi.1007642.s001</a>
  apa: Grah, R., &#38; Friedlander, T. (2020). Supporting information. Public Library
    of Science. <a href="https://doi.org/10.1371/journal.pcbi.1007642.s001">https://doi.org/10.1371/journal.pcbi.1007642.s001</a>
  chicago: Grah, Rok, and Tamar Friedlander. “Supporting Information.” Public Library
    of Science, 2020. <a href="https://doi.org/10.1371/journal.pcbi.1007642.s001">https://doi.org/10.1371/journal.pcbi.1007642.s001</a>.
  ieee: R. Grah and T. Friedlander, “Supporting information.” Public Library of Science,
    2020.
  ista: Grah R, Friedlander T. 2020. Supporting information, Public Library of Science,
    <a href="https://doi.org/10.1371/journal.pcbi.1007642.s001">10.1371/journal.pcbi.1007642.s001</a>.
  mla: Grah, Rok, and Tamar Friedlander. <i>Supporting Information</i>. Public Library
    of Science, 2020, doi:<a href="https://doi.org/10.1371/journal.pcbi.1007642.s001">10.1371/journal.pcbi.1007642.s001</a>.
  short: R. Grah, T. Friedlander, (2020).
date_created: 2021-08-06T07:15:04Z
date_published: 2020-02-25T00:00:00Z
date_updated: 2023-08-18T06:47:47Z
day: '25'
department:
- _id: GaTk
doi: 10.1371/journal.pcbi.1007642.s001
month: '02'
oa_version: Published Version
publisher: Public Library of Science
related_material:
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  - id: '7569'
    relation: used_in_publication
    status: public
status: public
title: Supporting information
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2020'
...
---
_id: '9777'
article_processing_charge: No
author:
- first_name: Rok
  full_name: Grah, Rok
  id: 483E70DE-F248-11E8-B48F-1D18A9856A87
  last_name: Grah
  orcid: 0000-0003-2539-3560
- first_name: Tamar
  full_name: Friedlander, Tamar
  last_name: Friedlander
citation:
  ama: Grah R, Friedlander T. Maximizing crosstalk. 2020. doi:<a href="https://doi.org/10.1371/journal.pcbi.1007642.s002">10.1371/journal.pcbi.1007642.s002</a>
  apa: Grah, R., &#38; Friedlander, T. (2020). Maximizing crosstalk. Public Library
    of Science. <a href="https://doi.org/10.1371/journal.pcbi.1007642.s002">https://doi.org/10.1371/journal.pcbi.1007642.s002</a>
  chicago: Grah, Rok, and Tamar Friedlander. “Maximizing Crosstalk.” Public Library
    of Science, 2020. <a href="https://doi.org/10.1371/journal.pcbi.1007642.s002">https://doi.org/10.1371/journal.pcbi.1007642.s002</a>.
  ieee: R. Grah and T. Friedlander, “Maximizing crosstalk.” Public Library of Science,
    2020.
  ista: Grah R, Friedlander T. 2020. Maximizing crosstalk, Public Library of Science,
    <a href="https://doi.org/10.1371/journal.pcbi.1007642.s002">10.1371/journal.pcbi.1007642.s002</a>.
  mla: Grah, Rok, and Tamar Friedlander. <i>Maximizing Crosstalk</i>. Public Library
    of Science, 2020, doi:<a href="https://doi.org/10.1371/journal.pcbi.1007642.s002">10.1371/journal.pcbi.1007642.s002</a>.
  short: R. Grah, T. Friedlander, (2020).
date_created: 2021-08-06T07:21:51Z
date_published: 2020-02-25T00:00:00Z
date_updated: 2023-09-12T11:02:25Z
day: '25'
department:
- _id: GaTk
doi: 10.1371/journal.pcbi.1007642.s002
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1371/journal.pcbi.1007642.s002
month: '02'
oa: 1
oa_version: None
publisher: Public Library of Science
related_material:
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  - id: '7569'
    relation: used_in_publication
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status: public
title: Maximizing crosstalk
type: research_data_reference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2020'
...
---
_id: '9779'
article_processing_charge: No
author:
- first_name: Rok
  full_name: Grah, Rok
  id: 483E70DE-F248-11E8-B48F-1D18A9856A87
  last_name: Grah
  orcid: 0000-0003-2539-3560
- first_name: Tamar
  full_name: Friedlander, Tamar
  last_name: Friedlander
citation:
  ama: Grah R, Friedlander T. Distribution of crosstalk values. 2020. doi:<a href="https://doi.org/10.1371/journal.pcbi.1007642.s003">10.1371/journal.pcbi.1007642.s003</a>
  apa: Grah, R., &#38; Friedlander, T. (2020). Distribution of crosstalk values. Public
    Library of Science. <a href="https://doi.org/10.1371/journal.pcbi.1007642.s003">https://doi.org/10.1371/journal.pcbi.1007642.s003</a>
  chicago: Grah, Rok, and Tamar Friedlander. “Distribution of Crosstalk Values.” Public
    Library of Science, 2020. <a href="https://doi.org/10.1371/journal.pcbi.1007642.s003">https://doi.org/10.1371/journal.pcbi.1007642.s003</a>.
  ieee: R. Grah and T. Friedlander, “Distribution of crosstalk values.” Public Library
    of Science, 2020.
  ista: Grah R, Friedlander T. 2020. Distribution of crosstalk values, Public Library
    of Science, <a href="https://doi.org/10.1371/journal.pcbi.1007642.s003">10.1371/journal.pcbi.1007642.s003</a>.
  mla: Grah, Rok, and Tamar Friedlander. <i>Distribution of Crosstalk Values</i>.
    Public Library of Science, 2020, doi:<a href="https://doi.org/10.1371/journal.pcbi.1007642.s003">10.1371/journal.pcbi.1007642.s003</a>.
  short: R. Grah, T. Friedlander, (2020).
date_created: 2021-08-06T07:24:37Z
date_published: 2020-02-25T00:00:00Z
date_updated: 2023-08-18T06:47:47Z
day: '25'
department:
- _id: GaTk
doi: 10.1371/journal.pcbi.1007642.s003
month: '02'
oa_version: Published Version
publisher: Public Library of Science
related_material:
  record:
  - id: '7569'
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status: public
title: Distribution of crosstalk values
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2020'
...
---
_id: '9780'
abstract:
- lang: eng
  text: "PADREV : 4,4'-dimethoxy[1,1'-biphenyl]-2,2',5,5'-tetrol\r\nSpace Group: C
    2 (5), Cell: a 24.488(16)Å b 5.981(4)Å c 3.911(3)Å, α 90° β 91.47(3)° γ 90°"
article_processing_charge: No
author:
- first_name: Werner
  full_name: Schlemmer, Werner
  last_name: Schlemmer
- first_name: Philipp
  full_name: Nothdurft, Philipp
  last_name: Nothdurft
- first_name: Alina
  full_name: Petzold, Alina
  last_name: Petzold
- first_name: Gisbert
  full_name: Riess, Gisbert
  last_name: Riess
- first_name: Philipp
  full_name: Frühwirt, Philipp
  last_name: Frühwirt
- first_name: Max
  full_name: Schmallegger, Max
  last_name: Schmallegger
- first_name: Georg
  full_name: Gescheidt-Demner, Georg
  last_name: Gescheidt-Demner
- first_name: Roland
  full_name: Fischer, Roland
  last_name: Fischer
- first_name: Stefan Alexander
  full_name: Freunberger, Stefan Alexander
  id: A8CA28E6-CE23-11E9-AD2D-EC27E6697425
  last_name: Freunberger
  orcid: 0000-0003-2902-5319
- first_name: Wolfgang
  full_name: Kern, Wolfgang
  last_name: Kern
- first_name: Stefan
  full_name: Spirk, Stefan
  last_name: Spirk
citation:
  ama: 'Schlemmer W, Nothdurft P, Petzold A, et al. CCDC 1991959: Experimental Crystal
    Structure Determination. 2020. doi:<a href="https://doi.org/10.5517/ccdc.csd.cc24vsrk">10.5517/ccdc.csd.cc24vsrk</a>'
  apa: 'Schlemmer, W., Nothdurft, P., Petzold, A., Riess, G., Frühwirt, P., Schmallegger,
    M., … Spirk, S. (2020). CCDC 1991959: Experimental Crystal Structure Determination.
    CCDC. <a href="https://doi.org/10.5517/ccdc.csd.cc24vsrk">https://doi.org/10.5517/ccdc.csd.cc24vsrk</a>'
  chicago: 'Schlemmer, Werner, Philipp Nothdurft, Alina Petzold, Gisbert Riess, Philipp
    Frühwirt, Max Schmallegger, Georg Gescheidt-Demner, et al. “CCDC 1991959: Experimental
    Crystal Structure Determination.” CCDC, 2020. <a href="https://doi.org/10.5517/ccdc.csd.cc24vsrk">https://doi.org/10.5517/ccdc.csd.cc24vsrk</a>.'
  ieee: 'W. Schlemmer <i>et al.</i>, “CCDC 1991959: Experimental Crystal Structure
    Determination.” CCDC, 2020.'
  ista: 'Schlemmer W, Nothdurft P, Petzold A, Riess G, Frühwirt P, Schmallegger M,
    Gescheidt-Demner G, Fischer R, Freunberger SA, Kern W, Spirk S. 2020. CCDC 1991959:
    Experimental Crystal Structure Determination, CCDC, <a href="https://doi.org/10.5517/ccdc.csd.cc24vsrk">10.5517/ccdc.csd.cc24vsrk</a>.'
  mla: 'Schlemmer, Werner, et al. <i>CCDC 1991959: Experimental Crystal Structure
    Determination</i>. CCDC, 2020, doi:<a href="https://doi.org/10.5517/ccdc.csd.cc24vsrk">10.5517/ccdc.csd.cc24vsrk</a>.'
  short: W. Schlemmer, P. Nothdurft, A. Petzold, G. Riess, P. Frühwirt, M. Schmallegger,
    G. Gescheidt-Demner, R. Fischer, S.A. Freunberger, W. Kern, S. Spirk, (2020).
date_created: 2021-08-06T07:41:07Z
date_published: 2020-03-22T00:00:00Z
date_updated: 2023-09-05T16:03:47Z
day: '22'
department:
- _id: StFr
doi: 10.5517/ccdc.csd.cc24vsrk
main_file_link:
- open_access: '1'
  url: https://dx.doi.org/10.5517/ccdc.csd.cc24vsrk
month: '03'
oa: 1
oa_version: Published Version
publisher: CCDC
related_material:
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  - id: '8329'
    relation: used_in_publication
    status: public
status: public
title: 'CCDC 1991959: Experimental Crystal Structure Determination'
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2020'
...
---
_id: '9781'
abstract:
- lang: eng
  text: We consider the Pekar functional on a ball in ℝ3. We prove uniqueness of minimizers,
    and a quadratic lower bound in terms of the distance to the minimizer. The latter
    follows from nondegeneracy of the Hessian at the minimum.
acknowledgement: We are grateful for the hospitality at the Mittag-Leffler Institute,
  where part of this work has been done. The work of the authors was supported by
  the European Research Council (ERC)under the European Union's Horizon 2020 research
  and innovation programme grant 694227.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Dario
  full_name: Feliciangeli, Dario
  id: 41A639AA-F248-11E8-B48F-1D18A9856A87
  last_name: Feliciangeli
  orcid: 0000-0003-0754-8530
- first_name: Robert
  full_name: Seiringer, Robert
  id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
  last_name: Seiringer
  orcid: 0000-0002-6781-0521
citation:
  ama: Feliciangeli D, Seiringer R. Uniqueness and nondegeneracy of minimizers of
    the Pekar functional on a ball. <i>SIAM Journal on Mathematical Analysis</i>.
    2020;52(1):605-622. doi:<a href="https://doi.org/10.1137/19m126284x">10.1137/19m126284x</a>
  apa: Feliciangeli, D., &#38; Seiringer, R. (2020). Uniqueness and nondegeneracy
    of minimizers of the Pekar functional on a ball. <i>SIAM Journal on Mathematical
    Analysis</i>. Society for Industrial &#38; Applied Mathematics . <a href="https://doi.org/10.1137/19m126284x">https://doi.org/10.1137/19m126284x</a>
  chicago: Feliciangeli, Dario, and Robert Seiringer. “Uniqueness and Nondegeneracy
    of Minimizers of the Pekar Functional on a Ball.” <i>SIAM Journal on Mathematical
    Analysis</i>. Society for Industrial &#38; Applied Mathematics , 2020. <a href="https://doi.org/10.1137/19m126284x">https://doi.org/10.1137/19m126284x</a>.
  ieee: D. Feliciangeli and R. Seiringer, “Uniqueness and nondegeneracy of minimizers
    of the Pekar functional on a ball,” <i>SIAM Journal on Mathematical Analysis</i>,
    vol. 52, no. 1. Society for Industrial &#38; Applied Mathematics , pp. 605–622,
    2020.
  ista: Feliciangeli D, Seiringer R. 2020. Uniqueness and nondegeneracy of minimizers
    of the Pekar functional on a ball. SIAM Journal on Mathematical Analysis. 52(1),
    605–622.
  mla: Feliciangeli, Dario, and Robert Seiringer. “Uniqueness and Nondegeneracy of
    Minimizers of the Pekar Functional on a Ball.” <i>SIAM Journal on Mathematical
    Analysis</i>, vol. 52, no. 1, Society for Industrial &#38; Applied Mathematics
    , 2020, pp. 605–22, doi:<a href="https://doi.org/10.1137/19m126284x">10.1137/19m126284x</a>.
  short: D. Feliciangeli, R. Seiringer, SIAM Journal on Mathematical Analysis 52 (2020)
    605–622.
date_created: 2021-08-06T07:34:16Z
date_published: 2020-02-12T00:00:00Z
date_updated: 2023-09-07T13:30:11Z
day: '12'
ddc:
- '510'
department:
- _id: RoSe
doi: 10.1137/19m126284x
ec_funded: 1
external_id:
  arxiv:
  - '1904.08647 '
  isi:
  - '000546967700022'
has_accepted_license: '1'
intvolume: '        52'
isi: 1
issue: '1'
keyword:
- Applied Mathematics
- Computational Mathematics
- Analysis
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1904.08647
month: '02'
oa: 1
oa_version: Preprint
page: 605-622
project:
- _id: 25C6DC12-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '694227'
  name: Analysis of quantum many-body systems
publication: SIAM Journal on Mathematical Analysis
publication_identifier:
  eissn:
  - 1095-7154
  issn:
  - 0036-1410
publication_status: published
publisher: 'Society for Industrial & Applied Mathematics '
quality_controlled: '1'
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  - id: '9733'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: Uniqueness and nondegeneracy of minimizers of the Pekar functional on a ball
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 52
year: '2020'
...
---
_id: '9798'
abstract:
- lang: eng
  text: Fitness interactions between mutations can influence a population’s evolution
    in many different ways. While epistatic effects are difficult to measure precisely,
    important information is captured by the mean and variance of log fitnesses for
    individuals carrying different numbers of mutations. We derive predictions for
    these quantities from a class of simple fitness landscapes, based on models of
    optimizing selection on quantitative traits. We also explore extensions to the
    models, including modular pleiotropy, variable effect sizes, mutational bias and
    maladaptation of the wild type. We illustrate our approach by reanalysing a large
    dataset of mutant effects in a yeast snoRNA. Though characterized by some large
    epistatic effects, these data give a good overall fit to the non-epistatic null
    model, suggesting that epistasis might have limited influence on the evolutionary
    dynamics in this system. We also show how the amount of epistasis depends on both
    the underlying fitness landscape and the distribution of mutations, and so is
    expected to vary in consistent ways between new mutations, standing variation
    and fixed mutations.
article_processing_charge: No
author:
- first_name: Christelle
  full_name: Fraisse, Christelle
  id: 32DF5794-F248-11E8-B48F-1D18A9856A87
  last_name: Fraisse
  orcid: 0000-0001-8441-5075
- first_name: John J.
  full_name: Welch, John J.
  last_name: Welch
citation:
  ama: Fraisse C, Welch JJ. Simulation code for Fig S2 from the distribution of epistasis
    on simple fitness landscapes. 2020. doi:<a href="https://doi.org/10.6084/m9.figshare.7957472.v1">10.6084/m9.figshare.7957472.v1</a>
  apa: Fraisse, C., &#38; Welch, J. J. (2020). Simulation code for Fig S2 from the
    distribution of epistasis on simple fitness landscapes. Royal Society of London.
    <a href="https://doi.org/10.6084/m9.figshare.7957472.v1">https://doi.org/10.6084/m9.figshare.7957472.v1</a>
  chicago: Fraisse, Christelle, and John J. Welch. “Simulation Code for Fig S2 from
    the Distribution of Epistasis on Simple Fitness Landscapes.” Royal Society of
    London, 2020. <a href="https://doi.org/10.6084/m9.figshare.7957472.v1">https://doi.org/10.6084/m9.figshare.7957472.v1</a>.
  ieee: C. Fraisse and J. J. Welch, “Simulation code for Fig S2 from the distribution
    of epistasis on simple fitness landscapes.” Royal Society of London, 2020.
  ista: Fraisse C, Welch JJ. 2020. Simulation code for Fig S2 from the distribution
    of epistasis on simple fitness landscapes, Royal Society of London, <a href="https://doi.org/10.6084/m9.figshare.7957472.v1">10.6084/m9.figshare.7957472.v1</a>.
  mla: Fraisse, Christelle, and John J. Welch. <i>Simulation Code for Fig S2 from
    the Distribution of Epistasis on Simple Fitness Landscapes</i>. Royal Society
    of London, 2020, doi:<a href="https://doi.org/10.6084/m9.figshare.7957472.v1">10.6084/m9.figshare.7957472.v1</a>.
  short: C. Fraisse, J.J. Welch, (2020).
date_created: 2021-08-06T11:18:15Z
date_published: 2020-10-15T00:00:00Z
date_updated: 2023-08-25T10:34:41Z
day: '15'
department:
- _id: BeVi
- _id: NiBa
doi: 10.6084/m9.figshare.7957472.v1
main_file_link:
- open_access: '1'
  url: https://doi.org/10.6084/m9.figshare.7957472.v1
month: '10'
oa: 1
oa_version: Published Version
publisher: Royal Society of London
related_material:
  record:
  - id: '6467'
    relation: used_in_publication
    status: public
status: public
title: Simulation code for Fig S2 from the distribution of epistasis on simple fitness
  landscapes
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2020'
...
---
_id: '9799'
abstract:
- lang: eng
  text: Fitness interactions between mutations can influence a population’s evolution
    in many different ways. While epistatic effects are difficult to measure precisely,
    important information is captured by the mean and variance of log fitnesses for
    individuals carrying different numbers of mutations. We derive predictions for
    these quantities from a class of simple fitness landscapes, based on models of
    optimizing selection on quantitative traits. We also explore extensions to the
    models, including modular pleiotropy, variable effect sizes, mutational bias and
    maladaptation of the wild type. We illustrate our approach by reanalysing a large
    dataset of mutant effects in a yeast snoRNA. Though characterized by some large
    epistatic effects, these data give a good overall fit to the non-epistatic null
    model, suggesting that epistasis might have limited influence on the evolutionary
    dynamics in this system. We also show how the amount of epistasis depends on both
    the underlying fitness landscape and the distribution of mutations, and so is
    expected to vary in consistent ways between new mutations, standing variation
    and fixed mutations.
article_processing_charge: No
author:
- first_name: Christelle
  full_name: Fraisse, Christelle
  id: 32DF5794-F248-11E8-B48F-1D18A9856A87
  last_name: Fraisse
  orcid: 0000-0001-8441-5075
- first_name: John J.
  full_name: Welch, John J.
  last_name: Welch
citation:
  ama: Fraisse C, Welch JJ. Simulation code for Fig S1 from the distribution of epistasis
    on simple fitness landscapes. 2020. doi:<a href="https://doi.org/10.6084/m9.figshare.7957469.v1">10.6084/m9.figshare.7957469.v1</a>
  apa: Fraisse, C., &#38; Welch, J. J. (2020). Simulation code for Fig S1 from the
    distribution of epistasis on simple fitness landscapes. Royal Society of London.
    <a href="https://doi.org/10.6084/m9.figshare.7957469.v1">https://doi.org/10.6084/m9.figshare.7957469.v1</a>
  chicago: Fraisse, Christelle, and John J. Welch. “Simulation Code for Fig S1 from
    the Distribution of Epistasis on Simple Fitness Landscapes.” Royal Society of
    London, 2020. <a href="https://doi.org/10.6084/m9.figshare.7957469.v1">https://doi.org/10.6084/m9.figshare.7957469.v1</a>.
  ieee: C. Fraisse and J. J. Welch, “Simulation code for Fig S1 from the distribution
    of epistasis on simple fitness landscapes.” Royal Society of London, 2020.
  ista: Fraisse C, Welch JJ. 2020. Simulation code for Fig S1 from the distribution
    of epistasis on simple fitness landscapes, Royal Society of London, <a href="https://doi.org/10.6084/m9.figshare.7957469.v1">10.6084/m9.figshare.7957469.v1</a>.
  mla: Fraisse, Christelle, and John J. Welch. <i>Simulation Code for Fig S1 from
    the Distribution of Epistasis on Simple Fitness Landscapes</i>. Royal Society
    of London, 2020, doi:<a href="https://doi.org/10.6084/m9.figshare.7957469.v1">10.6084/m9.figshare.7957469.v1</a>.
  short: C. Fraisse, J.J. Welch, (2020).
date_created: 2021-08-06T11:26:57Z
date_published: 2020-10-15T00:00:00Z
date_updated: 2023-08-25T10:34:41Z
day: '15'
department:
- _id: BeVi
- _id: NiBa
doi: 10.6084/m9.figshare.7957469.v1
main_file_link:
- open_access: '1'
  url: https://doi.org/10.6084/m9.figshare.7957469.v1
month: '10'
oa: 1
oa_version: Published Version
publisher: Royal Society of London
related_material:
  record:
  - id: '6467'
    relation: used_in_publication
    status: public
status: public
title: Simulation code for Fig S1 from the distribution of epistasis on simple fitness
  landscapes
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2020'
...
---
_id: '9814'
abstract:
- lang: eng
  text: Data and mathematica notebooks for plotting figures from Language learning
    with communication between learners
article_processing_charge: No
author:
- first_name: Rasmus
  full_name: Ibsen-Jensen, Rasmus
  id: 3B699956-F248-11E8-B48F-1D18A9856A87
  last_name: Ibsen-Jensen
  orcid: 0000-0003-4783-0389
- first_name: Josef
  full_name: Tkadlec, Josef
  id: 3F24CCC8-F248-11E8-B48F-1D18A9856A87
  last_name: Tkadlec
  orcid: 0000-0002-1097-9684
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Martin
  full_name: Nowak, Martin
  last_name: Nowak
citation:
  ama: Ibsen-Jensen R, Tkadlec J, Chatterjee K, Nowak M. Data and mathematica notebooks
    for plotting figures from language learning with communication between learners
    from language acquisition with communication between learners. 2020. doi:<a href="https://doi.org/10.6084/m9.figshare.5973013.v1">10.6084/m9.figshare.5973013.v1</a>
  apa: Ibsen-Jensen, R., Tkadlec, J., Chatterjee, K., &#38; Nowak, M. (2020). Data
    and mathematica notebooks for plotting figures from language learning with communication
    between learners from language acquisition with communication between learners.
    Royal Society. <a href="https://doi.org/10.6084/m9.figshare.5973013.v1">https://doi.org/10.6084/m9.figshare.5973013.v1</a>
  chicago: Ibsen-Jensen, Rasmus, Josef Tkadlec, Krishnendu Chatterjee, and Martin
    Nowak. “Data and Mathematica Notebooks for Plotting Figures from Language Learning
    with Communication between Learners from Language Acquisition with Communication
    between Learners.” Royal Society, 2020. <a href="https://doi.org/10.6084/m9.figshare.5973013.v1">https://doi.org/10.6084/m9.figshare.5973013.v1</a>.
  ieee: R. Ibsen-Jensen, J. Tkadlec, K. Chatterjee, and M. Nowak, “Data and mathematica
    notebooks for plotting figures from language learning with communication between
    learners from language acquisition with communication between learners.” Royal
    Society, 2020.
  ista: Ibsen-Jensen R, Tkadlec J, Chatterjee K, Nowak M. 2020. Data and mathematica
    notebooks for plotting figures from language learning with communication between
    learners from language acquisition with communication between learners, Royal
    Society, <a href="https://doi.org/10.6084/m9.figshare.5973013.v1">10.6084/m9.figshare.5973013.v1</a>.
  mla: Ibsen-Jensen, Rasmus, et al. <i>Data and Mathematica Notebooks for Plotting
    Figures from Language Learning with Communication between Learners from Language
    Acquisition with Communication between Learners</i>. Royal Society, 2020, doi:<a
    href="https://doi.org/10.6084/m9.figshare.5973013.v1">10.6084/m9.figshare.5973013.v1</a>.
  short: R. Ibsen-Jensen, J. Tkadlec, K. Chatterjee, M. Nowak, (2020).
date_created: 2021-08-06T13:09:57Z
date_published: 2020-10-15T00:00:00Z
date_updated: 2023-10-18T06:36:00Z
day: '15'
department:
- _id: KrCh
doi: 10.6084/m9.figshare.5973013.v1
main_file_link:
- open_access: '1'
  url: https://doi.org/10.6084/m9.figshare.5973013.v1
month: '10'
oa: 1
oa_version: Published Version
publisher: Royal Society
related_material:
  record:
  - id: '198'
    relation: used_in_publication
    status: public
status: public
title: Data and mathematica notebooks for plotting figures from language learning
  with communication between learners from language acquisition with communication
  between learners
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2020'
...
---
_id: '9878'
article_processing_charge: No
author:
- first_name: Chitrak
  full_name: Gupta, Chitrak
  last_name: Gupta
- first_name: Umesh
  full_name: Khaniya, Umesh
  last_name: Khaniya
- first_name: Chun Kit
  full_name: Chan, Chun Kit
  last_name: Chan
- first_name: Francois
  full_name: Dehez, Francois
  last_name: Dehez
- first_name: Mrinal
  full_name: Shekhar, Mrinal
  last_name: Shekhar
- first_name: M.R.
  full_name: Gunner, M.R.
  last_name: Gunner
- first_name: Leonid A
  full_name: Sazanov, Leonid A
  id: 338D39FE-F248-11E8-B48F-1D18A9856A87
  last_name: Sazanov
  orcid: 0000-0002-0977-7989
- first_name: Christophe
  full_name: Chipot, Christophe
  last_name: Chipot
- first_name: Abhishek
  full_name: Singharoy, Abhishek
  last_name: Singharoy
citation:
  ama: Gupta C, Khaniya U, Chan CK, et al. Movies. 2020. doi:<a href="https://doi.org/10.1021/jacs.9b13450.s002">10.1021/jacs.9b13450.s002</a>
  apa: Gupta, C., Khaniya, U., Chan, C. K., Dehez, F., Shekhar, M., Gunner, M. R.,
    … Singharoy, A. (2020). Movies. American Chemical Society. <a href="https://doi.org/10.1021/jacs.9b13450.s002">https://doi.org/10.1021/jacs.9b13450.s002</a>
  chicago: Gupta, Chitrak, Umesh Khaniya, Chun Kit Chan, Francois Dehez, Mrinal Shekhar,
    M.R. Gunner, Leonid A Sazanov, Christophe Chipot, and Abhishek Singharoy. “Movies.”
    American Chemical Society, 2020. <a href="https://doi.org/10.1021/jacs.9b13450.s002">https://doi.org/10.1021/jacs.9b13450.s002</a>.
  ieee: C. Gupta <i>et al.</i>, “Movies.” American Chemical Society, 2020.
  ista: Gupta C, Khaniya U, Chan CK, Dehez F, Shekhar M, Gunner MR, Sazanov LA, Chipot
    C, Singharoy A. 2020. Movies, American Chemical Society, <a href="https://doi.org/10.1021/jacs.9b13450.s002">10.1021/jacs.9b13450.s002</a>.
  mla: Gupta, Chitrak, et al. <i>Movies</i>. American Chemical Society, 2020, doi:<a
    href="https://doi.org/10.1021/jacs.9b13450.s002">10.1021/jacs.9b13450.s002</a>.
  short: C. Gupta, U. Khaniya, C.K. Chan, F. Dehez, M. Shekhar, M.R. Gunner, L.A.
    Sazanov, C. Chipot, A. Singharoy, (2020).
date_created: 2021-08-11T09:18:54Z
date_published: 2020-05-20T00:00:00Z
date_updated: 2023-08-22T07:49:38Z
day: '20'
department:
- _id: LeSa
doi: 10.1021/jacs.9b13450.s002
month: '05'
oa_version: Published Version
publisher: American Chemical Society
related_material:
  record:
  - id: '8040'
    relation: used_in_publication
    status: public
status: public
title: Movies
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2020'
...
---
_id: '9885'
abstract:
- lang: eng
  text: Data obtained from the fine-grained simulations used in Figures 2-5, data
    obtained from the coarse-grained numerical calculations used in Figure 6, and
    a sample script for the fine-grained simulation as a Jupyter notebook (ZIP)
article_processing_charge: No
author:
- first_name: Mehmet C
  full_name: Ucar, Mehmet C
  id: 50B2A802-6007-11E9-A42B-EB23E6697425
  last_name: Ucar
  orcid: 0000-0003-0506-4217
- first_name: Reinhard
  full_name: Lipowsky, Reinhard
  last_name: Lipowsky
citation:
  ama: Ucar MC, Lipowsky R. MURL_Dataz. 2020. doi:<a href="https://doi.org/10.1021/acs.nanolett.9b04445.s002">10.1021/acs.nanolett.9b04445.s002</a>
  apa: Ucar, M. C., &#38; Lipowsky, R. (2020). MURL_Dataz. American Chemical Society
    . <a href="https://doi.org/10.1021/acs.nanolett.9b04445.s002">https://doi.org/10.1021/acs.nanolett.9b04445.s002</a>
  chicago: Ucar, Mehmet C, and Reinhard Lipowsky. “MURL_Dataz.” American Chemical
    Society , 2020. <a href="https://doi.org/10.1021/acs.nanolett.9b04445.s002">https://doi.org/10.1021/acs.nanolett.9b04445.s002</a>.
  ieee: M. C. Ucar and R. Lipowsky, “MURL_Dataz.” American Chemical Society , 2020.
  ista: Ucar MC, Lipowsky R. 2020. MURL_Dataz, American Chemical Society , <a href="https://doi.org/10.1021/acs.nanolett.9b04445.s002">10.1021/acs.nanolett.9b04445.s002</a>.
  mla: Ucar, Mehmet C., and Reinhard Lipowsky. <i>MURL_Dataz</i>. American Chemical
    Society , 2020, doi:<a href="https://doi.org/10.1021/acs.nanolett.9b04445.s002">10.1021/acs.nanolett.9b04445.s002</a>.
  short: M.C. Ucar, R. Lipowsky, (2020).
date_created: 2021-08-11T13:16:03Z
date_published: 2020-01-08T00:00:00Z
date_updated: 2023-08-17T14:07:52Z
day: '08'
department:
- _id: EdHa
doi: 10.1021/acs.nanolett.9b04445.s002
month: '01'
oa_version: Published Version
publisher: 'American Chemical Society '
related_material:
  record:
  - id: '7166'
    relation: used_in_publication
    status: public
status: public
title: MURL_Dataz
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2020'
...
---
_id: '10861'
abstract:
- lang: eng
  text: We introduce in this paper AMT2.0, a tool for qualitative and quantitative
    analysis of hybrid continuous and Boolean signals that combine numerical values
    and discrete events. The evaluation of the signals is based on rich temporal specifications
    expressed in extended signal temporal logic, which integrates timed regular expressions
    within signal temporal logic. The tool features qualitative monitoring (property
    satisfaction checking), trace diagnostics for explaining and justifying property
    violations and specification-driven measurement of quantitative features of the
    signal. We demonstrate the tool functionality on several running examples and
    case studies, and evaluate its performance.
article_processing_charge: No
article_type: original
author:
- first_name: Dejan
  full_name: Nickovic, Dejan
  id: 41BCEE5C-F248-11E8-B48F-1D18A9856A87
  last_name: Nickovic
- first_name: Olivier
  full_name: Lebeltel, Olivier
  last_name: Lebeltel
- first_name: Oded
  full_name: Maler, Oded
  last_name: Maler
- first_name: Thomas
  full_name: Ferrere, Thomas
  id: 40960E6E-F248-11E8-B48F-1D18A9856A87
  last_name: Ferrere
  orcid: 0000-0001-5199-3143
- first_name: Dogan
  full_name: Ulus, Dogan
  last_name: Ulus
citation:
  ama: 'Nickovic D, Lebeltel O, Maler O, Ferrere T, Ulus D. AMT 2.0: Qualitative and
    quantitative trace analysis with extended signal temporal logic. <i>International
    Journal on Software Tools for Technology Transfer</i>. 2020;22(6):741-758. doi:<a
    href="https://doi.org/10.1007/s10009-020-00582-z">10.1007/s10009-020-00582-z</a>'
  apa: 'Nickovic, D., Lebeltel, O., Maler, O., Ferrere, T., &#38; Ulus, D. (2020).
    AMT 2.0: Qualitative and quantitative trace analysis with extended signal temporal
    logic. <i>International Journal on Software Tools for Technology Transfer</i>.
    Springer Nature. <a href="https://doi.org/10.1007/s10009-020-00582-z">https://doi.org/10.1007/s10009-020-00582-z</a>'
  chicago: 'Nickovic, Dejan, Olivier Lebeltel, Oded Maler, Thomas Ferrere, and Dogan
    Ulus. “AMT 2.0: Qualitative and Quantitative Trace Analysis with Extended Signal
    Temporal Logic.” <i>International Journal on Software Tools for Technology Transfer</i>.
    Springer Nature, 2020. <a href="https://doi.org/10.1007/s10009-020-00582-z">https://doi.org/10.1007/s10009-020-00582-z</a>.'
  ieee: 'D. Nickovic, O. Lebeltel, O. Maler, T. Ferrere, and D. Ulus, “AMT 2.0: Qualitative
    and quantitative trace analysis with extended signal temporal logic,” <i>International
    Journal on Software Tools for Technology Transfer</i>, vol. 22, no. 6. Springer
    Nature, pp. 741–758, 2020.'
  ista: 'Nickovic D, Lebeltel O, Maler O, Ferrere T, Ulus D. 2020. AMT 2.0: Qualitative
    and quantitative trace analysis with extended signal temporal logic. International
    Journal on Software Tools for Technology Transfer. 22(6), 741–758.'
  mla: 'Nickovic, Dejan, et al. “AMT 2.0: Qualitative and Quantitative Trace Analysis
    with Extended Signal Temporal Logic.” <i>International Journal on Software Tools
    for Technology Transfer</i>, vol. 22, no. 6, Springer Nature, 2020, pp. 741–58,
    doi:<a href="https://doi.org/10.1007/s10009-020-00582-z">10.1007/s10009-020-00582-z</a>.'
  short: D. Nickovic, O. Lebeltel, O. Maler, T. Ferrere, D. Ulus, International Journal
    on Software Tools for Technology Transfer 22 (2020) 741–758.
date_created: 2022-03-18T10:10:53Z
date_published: 2020-08-03T00:00:00Z
date_updated: 2023-09-08T11:52:02Z
day: '03'
department:
- _id: ToHe
doi: 10.1007/s10009-020-00582-z
external_id:
  isi:
  - '000555398600001'
intvolume: '        22'
isi: 1
issue: '6'
keyword:
- Information Systems
- Software
language:
- iso: eng
month: '08'
oa_version: None
page: 741-758
publication: International Journal on Software Tools for Technology Transfer
publication_identifier:
  eissn:
  - 1433-2787
  issn:
  - 1433-2779
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
  record:
  - id: '299'
    relation: earlier_version
    status: public
scopus_import: '1'
status: public
title: 'AMT 2.0: Qualitative and quantitative trace analysis with extended signal
  temporal logic'
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 22
year: '2020'
...
---
_id: '10862'
abstract:
- lang: eng
  text: We consider the sum of two large Hermitian matrices A and B with a Haar unitary
    conjugation bringing them into a general relative position. We prove that the
    eigenvalue density on the scale slightly above the local eigenvalue spacing is
    asymptotically given by the free additive convolution of the laws of A and B as
    the dimension of the matrix increases. This implies optimal rigidity of the eigenvalues
    and optimal rate of convergence in Voiculescu's theorem. Our previous works [4],
    [5] established these results in the bulk spectrum, the current paper completely
    settles the problem at the spectral edges provided they have the typical square-root
    behavior. The key element of our proof is to compensate the deterioration of the
    stability of the subordination equations by sharp error estimates that properly
    account for the local density near the edge. Our results also hold if the Haar
    unitary matrix is replaced by the Haar orthogonal matrix.
acknowledgement: Partially supported by ERC Advanced Grant RANMAT No. 338804.
article_number: '108639'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Zhigang
  full_name: Bao, Zhigang
  id: 442E6A6C-F248-11E8-B48F-1D18A9856A87
  last_name: Bao
  orcid: 0000-0003-3036-1475
- first_name: László
  full_name: Erdös, László
  id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
  last_name: Erdös
  orcid: 0000-0001-5366-9603
- first_name: Kevin
  full_name: Schnelli, Kevin
  last_name: Schnelli
citation:
  ama: Bao Z, Erdös L, Schnelli K. Spectral rigidity for addition of random matrices
    at the regular edge. <i>Journal of Functional Analysis</i>. 2020;279(7). doi:<a
    href="https://doi.org/10.1016/j.jfa.2020.108639">10.1016/j.jfa.2020.108639</a>
  apa: Bao, Z., Erdös, L., &#38; Schnelli, K. (2020). Spectral rigidity for addition
    of random matrices at the regular edge. <i>Journal of Functional Analysis</i>.
    Elsevier. <a href="https://doi.org/10.1016/j.jfa.2020.108639">https://doi.org/10.1016/j.jfa.2020.108639</a>
  chicago: Bao, Zhigang, László Erdös, and Kevin Schnelli. “Spectral Rigidity for
    Addition of Random Matrices at the Regular Edge.” <i>Journal of Functional Analysis</i>.
    Elsevier, 2020. <a href="https://doi.org/10.1016/j.jfa.2020.108639">https://doi.org/10.1016/j.jfa.2020.108639</a>.
  ieee: Z. Bao, L. Erdös, and K. Schnelli, “Spectral rigidity for addition of random
    matrices at the regular edge,” <i>Journal of Functional Analysis</i>, vol. 279,
    no. 7. Elsevier, 2020.
  ista: Bao Z, Erdös L, Schnelli K. 2020. Spectral rigidity for addition of random
    matrices at the regular edge. Journal of Functional Analysis. 279(7), 108639.
  mla: Bao, Zhigang, et al. “Spectral Rigidity for Addition of Random Matrices at
    the Regular Edge.” <i>Journal of Functional Analysis</i>, vol. 279, no. 7, 108639,
    Elsevier, 2020, doi:<a href="https://doi.org/10.1016/j.jfa.2020.108639">10.1016/j.jfa.2020.108639</a>.
  short: Z. Bao, L. Erdös, K. Schnelli, Journal of Functional Analysis 279 (2020).
date_created: 2022-03-18T10:18:59Z
date_published: 2020-10-15T00:00:00Z
date_updated: 2023-08-24T14:08:42Z
day: '15'
department:
- _id: LaEr
doi: 10.1016/j.jfa.2020.108639
ec_funded: 1
external_id:
  arxiv:
  - '1708.01597'
  isi:
  - '000559623200009'
intvolume: '       279'
isi: 1
issue: '7'
keyword:
- Analysis
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1708.01597
month: '10'
oa: 1
oa_version: Preprint
project:
- _id: 258DCDE6-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '338804'
  name: Random matrices, universality and disordered quantum systems
publication: Journal of Functional Analysis
publication_identifier:
  issn:
  - 0022-1236
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Spectral rigidity for addition of random matrices at the regular edge
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 279
year: '2020'
...
---
_id: '10867'
abstract:
- lang: eng
  text: In this paper we find a tight estimate for Gromov’s waist of the balls in
    spaces of constant curvature, deduce the estimates for the balls in Riemannian
    manifolds with upper bounds on the curvature (CAT(ϰ)-spaces), and establish similar
    result for normed spaces.
acknowledgement: ' Supported by the Russian Foundation for Basic Research grant 18-01-00036.'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Arseniy
  full_name: Akopyan, Arseniy
  id: 430D2C90-F248-11E8-B48F-1D18A9856A87
  last_name: Akopyan
  orcid: 0000-0002-2548-617X
- first_name: Roman
  full_name: Karasev, Roman
  last_name: Karasev
citation:
  ama: Akopyan A, Karasev R. Waist of balls in hyperbolic and spherical spaces. <i>International
    Mathematics Research Notices</i>. 2020;2020(3):669-697. doi:<a href="https://doi.org/10.1093/imrn/rny037">10.1093/imrn/rny037</a>
  apa: Akopyan, A., &#38; Karasev, R. (2020). Waist of balls in hyperbolic and spherical
    spaces. <i>International Mathematics Research Notices</i>. Oxford University Press.
    <a href="https://doi.org/10.1093/imrn/rny037">https://doi.org/10.1093/imrn/rny037</a>
  chicago: Akopyan, Arseniy, and Roman Karasev. “Waist of Balls in Hyperbolic and
    Spherical Spaces.” <i>International Mathematics Research Notices</i>. Oxford University
    Press, 2020. <a href="https://doi.org/10.1093/imrn/rny037">https://doi.org/10.1093/imrn/rny037</a>.
  ieee: A. Akopyan and R. Karasev, “Waist of balls in hyperbolic and spherical spaces,”
    <i>International Mathematics Research Notices</i>, vol. 2020, no. 3. Oxford University
    Press, pp. 669–697, 2020.
  ista: Akopyan A, Karasev R. 2020. Waist of balls in hyperbolic and spherical spaces.
    International Mathematics Research Notices. 2020(3), 669–697.
  mla: Akopyan, Arseniy, and Roman Karasev. “Waist of Balls in Hyperbolic and Spherical
    Spaces.” <i>International Mathematics Research Notices</i>, vol. 2020, no. 3,
    Oxford University Press, 2020, pp. 669–97, doi:<a href="https://doi.org/10.1093/imrn/rny037">10.1093/imrn/rny037</a>.
  short: A. Akopyan, R. Karasev, International Mathematics Research Notices 2020 (2020)
    669–697.
date_created: 2022-03-18T11:39:30Z
date_published: 2020-02-01T00:00:00Z
date_updated: 2023-08-24T14:19:55Z
day: '01'
department:
- _id: HeEd
doi: 10.1093/imrn/rny037
external_id:
  arxiv:
  - '1702.07513'
  isi:
  - '000522852700002'
intvolume: '      2020'
isi: 1
issue: '3'
keyword:
- General Mathematics
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1702.07513
month: '02'
oa: 1
oa_version: Preprint
page: 669-697
publication: International Mathematics Research Notices
publication_identifier:
  eissn:
  - 1687-0247
  issn:
  - 1073-7928
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Waist of balls in hyperbolic and spherical spaces
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 2020
year: '2020'
...
---
_id: '12190'
abstract:
- lang: eng
  text: Meiotic crossover frequency varies within genomes, which influences genetic
    diversity and adaptation. In turn, genetic variation within populations can act
    to modify crossover frequency in cis and trans. To identify genetic variation
    that controls meiotic crossover frequency, we screened Arabidopsis accessions
    using fluorescent recombination reporters. We mapped a genetic modifier of crossover
    frequency in Col × Bur populations of Arabidopsis to a premature stop codon within
    TBP-ASSOCIATED FACTOR 4b (TAF4b), which encodes a subunit of the RNA polymerase
    II general transcription factor TFIID. The Arabidopsis taf4b mutation is a rare
    variant found in the British Isles, originating in South-West Ireland. Using genetics,
    genomics, and immunocytology, we demonstrate a genome-wide decrease in taf4b crossovers,
    with strongest reduction in the sub-telomeric regions. Using RNA sequencing (RNA-seq)
    from purified meiocytes, we show that TAF4b expression is meiocyte enriched, whereas
    its paralog TAF4 is broadly expressed. Consistent with the role of TFIID in promoting
    gene expression, RNA-seq of wild-type and taf4b meiocytes identified widespread
    transcriptional changes, including in genes that regulate the meiotic cell cycle
    and recombination. Therefore, TAF4b duplication is associated with acquisition
    of meiocyte-specific expression and promotion of germline transcription, which
    act directly or indirectly to elevate crossovers. This identifies a novel mode
    of meiotic recombination control via a general transcription factor.
acknowledgement: "We thank Gregory Copenhaver (University of North Carolina), Avraham
  Levy (The Weizmann Institute), and Scott Poethig (University of Pennsylvania) for
  FTLs; Piotr Ziolkowski for Col-420/Bur seed; Sureshkumar Balasubramanian\r\n(Monash
  University) for providing British and Irish Arabidopsis accessions; Mathilde Grelon
  (INRA, Versailles) for providing the MLH1 antibody; and the Gurdon Institute for
  access to microscopes. This work was supported by a BBSRC DTP studentship (E.J.L.),
  European Research Area Network for Coordinating Action in Plant Sciences/BBSRC ‘‘DeCOP’’
  (BB/M004937/1; C.L.), a BBSRC David Phillips Fellowship (BB/L025043/1; H.G. and
  X.F.), the European Research Council (CoG ‘‘SynthHotspot,’’ A.J.T., C.L., and I.R.H.;
  StG ‘‘SexMeth,’’ X.F.), and a Sainsbury Charitable Foundation Studentship (A.R.B.)."
article_processing_charge: No
article_type: original
author:
- first_name: Emma J.
  full_name: Lawrence, Emma J.
  last_name: Lawrence
- first_name: Hongbo
  full_name: Gao, Hongbo
  last_name: Gao
- first_name: Andrew J.
  full_name: Tock, Andrew J.
  last_name: Tock
- first_name: Christophe
  full_name: Lambing, Christophe
  last_name: Lambing
- first_name: Alexander R.
  full_name: Blackwell, Alexander R.
  last_name: Blackwell
- first_name: Xiaoqi
  full_name: Feng, Xiaoqi
  id: e0164712-22ee-11ed-b12a-d80fcdf35958
  last_name: Feng
  orcid: 0000-0002-4008-1234
- first_name: Ian R.
  full_name: Henderson, Ian R.
  last_name: Henderson
citation:
  ama: Lawrence EJ, Gao H, Tock AJ, et al. Natural variation in TBP-ASSOCIATED FACTOR
    4b controls meiotic crossover and germline transcription in Arabidopsis. <i>Current
    Biology</i>. 2019;29(16):2676-2686.e3. doi:<a href="https://doi.org/10.1016/j.cub.2019.06.084">10.1016/j.cub.2019.06.084</a>
  apa: Lawrence, E. J., Gao, H., Tock, A. J., Lambing, C., Blackwell, A. R., Feng,
    X., &#38; Henderson, I. R. (2019). Natural variation in TBP-ASSOCIATED FACTOR
    4b controls meiotic crossover and germline transcription in Arabidopsis. <i>Current
    Biology</i>. Elsevier BV. <a href="https://doi.org/10.1016/j.cub.2019.06.084">https://doi.org/10.1016/j.cub.2019.06.084</a>
  chicago: Lawrence, Emma J., Hongbo Gao, Andrew J. Tock, Christophe Lambing, Alexander
    R. Blackwell, Xiaoqi Feng, and Ian R. Henderson. “Natural Variation in TBP-ASSOCIATED
    FACTOR 4b Controls Meiotic Crossover and Germline Transcription in Arabidopsis.”
    <i>Current Biology</i>. Elsevier BV, 2019. <a href="https://doi.org/10.1016/j.cub.2019.06.084">https://doi.org/10.1016/j.cub.2019.06.084</a>.
  ieee: E. J. Lawrence <i>et al.</i>, “Natural variation in TBP-ASSOCIATED FACTOR
    4b controls meiotic crossover and germline transcription in Arabidopsis,” <i>Current
    Biology</i>, vol. 29, no. 16. Elsevier BV, p. 2676–2686.e3, 2019.
  ista: Lawrence EJ, Gao H, Tock AJ, Lambing C, Blackwell AR, Feng X, Henderson IR.
    2019. Natural variation in TBP-ASSOCIATED FACTOR 4b controls meiotic crossover
    and germline transcription in Arabidopsis. Current Biology. 29(16), 2676–2686.e3.
  mla: Lawrence, Emma J., et al. “Natural Variation in TBP-ASSOCIATED FACTOR 4b Controls
    Meiotic Crossover and Germline Transcription in Arabidopsis.” <i>Current Biology</i>,
    vol. 29, no. 16, Elsevier BV, 2019, p. 2676–2686.e3, doi:<a href="https://doi.org/10.1016/j.cub.2019.06.084">10.1016/j.cub.2019.06.084</a>.
  short: E.J. Lawrence, H. Gao, A.J. Tock, C. Lambing, A.R. Blackwell, X. Feng, I.R.
    Henderson, Current Biology 29 (2019) 2676–2686.e3.
date_created: 2023-01-16T09:16:33Z
date_published: 2019-08-19T00:00:00Z
date_updated: 2023-05-08T10:54:54Z
day: '19'
department:
- _id: XiFe
doi: 10.1016/j.cub.2019.06.084
extern: '1'
external_id:
  pmid:
  - '31378616'
intvolume: '        29'
issue: '16'
keyword:
- General Agricultural and Biological Sciences
- General Biochemistry
- Genetics and Molecular Biology
language:
- iso: eng
month: '08'
oa_version: None
page: 2676-2686.e3
pmid: 1
publication: Current Biology
publication_identifier:
  issn:
  - 0960-9822
publication_status: published
publisher: Elsevier BV
quality_controlled: '1'
scopus_import: '1'
status: public
title: Natural variation in TBP-ASSOCIATED FACTOR 4b controls meiotic crossover and
  germline transcription in Arabidopsis
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 29
year: '2019'
...
---
_id: '12192'
abstract:
- lang: eng
  text: Transposable elements (TEs), the movement of which can damage the genome,
    are epigenetically silenced in eukaryotes. Intriguingly, TEs are activated in
    the sperm companion cell – vegetative cell (VC) – of the flowering plant Arabidopsis
    thaliana. However, the extent and mechanism of this activation are unknown. Here
    we show that about 100 heterochromatic TEs are activated in VCs, mostly by DEMETER-catalyzed
    DNA demethylation. We further demonstrate that DEMETER access to some of these
    TEs is permitted by the natural depletion of linker histone H1 in VCs. Ectopically
    expressed H1 suppresses TEs in VCs by reducing DNA demethylation and via a methylation-independent
    mechanism. We demonstrate that H1 is required for heterochromatin condensation
    in plant cells and show that H1 overexpression creates heterochromatic foci in
    the VC progenitor cell. Taken together, our results demonstrate that the natural
    depletion of H1 during male gametogenesis facilitates DEMETER-directed DNA demethylation,
    heterochromatin relaxation, and TE activation.
acknowledgement: We thank David Twell for the pDONR-P4-P1R-pLAT52 and pDONR-P2R-P3-mRFP
  vectors, the John Innes Centre Bioimaging Facility (Elaine Barclay and Grant Calder)
  for their assistance with microscopy, and the Norwich BioScience Institute Partnership
  Computing infrastructure for Science Group for High Performance Computing resources.
  This work was funded by a Biotechnology and Biological Sciences Research Council
  (BBSRC) David Phillips Fellowship (BB/L025043/1; SH, JZ and XF), a European Research
  Council Starting Grant ('SexMeth' 804981; XF) and a Grant to Exceptional Researchers
  by the Gatsby Charitable Foundation (SH and XF).
article_number: '42530'
article_processing_charge: No
article_type: original
author:
- first_name: Shengbo
  full_name: He, Shengbo
  last_name: He
- first_name: Martin
  full_name: Vickers, Martin
  last_name: Vickers
- first_name: Jingyi
  full_name: Zhang, Jingyi
  last_name: Zhang
- first_name: Xiaoqi
  full_name: Feng, Xiaoqi
  id: e0164712-22ee-11ed-b12a-d80fcdf35958
  last_name: Feng
  orcid: 0000-0002-4008-1234
citation:
  ama: He S, Vickers M, Zhang J, Feng X. Natural depletion of histone H1 in sex cells
    causes DNA demethylation, heterochromatin decondensation and transposon activation.
    <i>eLife</i>. 2019;8. doi:<a href="https://doi.org/10.7554/elife.42530">10.7554/elife.42530</a>
  apa: He, S., Vickers, M., Zhang, J., &#38; Feng, X. (2019). Natural depletion of
    histone H1 in sex cells causes DNA demethylation, heterochromatin decondensation
    and transposon activation. <i>ELife</i>. eLife Sciences Publications, Ltd. <a
    href="https://doi.org/10.7554/elife.42530">https://doi.org/10.7554/elife.42530</a>
  chicago: He, Shengbo, Martin Vickers, Jingyi Zhang, and Xiaoqi Feng. “Natural Depletion
    of Histone H1 in Sex Cells Causes DNA Demethylation, Heterochromatin Decondensation
    and Transposon Activation.” <i>ELife</i>. eLife Sciences Publications, Ltd, 2019.
    <a href="https://doi.org/10.7554/elife.42530">https://doi.org/10.7554/elife.42530</a>.
  ieee: S. He, M. Vickers, J. Zhang, and X. Feng, “Natural depletion of histone H1
    in sex cells causes DNA demethylation, heterochromatin decondensation and transposon
    activation,” <i>eLife</i>, vol. 8. eLife Sciences Publications, Ltd, 2019.
  ista: He S, Vickers M, Zhang J, Feng X. 2019. Natural depletion of histone H1 in
    sex cells causes DNA demethylation, heterochromatin decondensation and transposon
    activation. eLife. 8, 42530.
  mla: He, Shengbo, et al. “Natural Depletion of Histone H1 in Sex Cells Causes DNA
    Demethylation, Heterochromatin Decondensation and Transposon Activation.” <i>ELife</i>,
    vol. 8, 42530, eLife Sciences Publications, Ltd, 2019, doi:<a href="https://doi.org/10.7554/elife.42530">10.7554/elife.42530</a>.
  short: S. He, M. Vickers, J. Zhang, X. Feng, ELife 8 (2019).
date_created: 2023-01-16T09:17:21Z
date_published: 2019-05-28T00:00:00Z
date_updated: 2023-05-08T10:54:12Z
day: '28'
ddc:
- '580'
department:
- _id: XiFe
doi: 10.7554/elife.42530
extern: '1'
external_id:
  unknown:
  - '31135340'
file:
- access_level: open_access
  checksum: ea6b89c20d59e5eb3646916fe5d568ad
  content_type: application/pdf
  creator: alisjak
  date_created: 2023-02-07T09:42:46Z
  date_updated: 2023-02-07T09:42:46Z
  file_id: '12525'
  file_name: 2019_elife_He.pdf
  file_size: 2493837
  relation: main_file
  success: 1
file_date_updated: 2023-02-07T09:42:46Z
has_accepted_license: '1'
intvolume: '         8'
keyword:
- General Immunology and Microbiology
- General Biochemistry
- Genetics and Molecular Biology
- General Medicine
- General Neuroscience
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594752/
month: '05'
oa: 1
oa_version: Published Version
publication: eLife
publication_identifier:
  issn:
  - 2050-084X
publication_status: published
publisher: eLife Sciences Publications, Ltd
quality_controlled: '1'
scopus_import: '1'
status: public
title: Natural depletion of histone H1 in sex cells causes DNA demethylation, heterochromatin
  decondensation and transposon activation
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 8
year: '2019'
...
---
_id: '13067'
abstract:
- lang: eng
  text: Genetic incompatibilities contribute to reproductive isolation between many
    diverging populations, but it is still unclear to what extent they play a role
    if divergence happens with gene flow. In contact zones between the "Crab" and
    "Wave" ecotypes of the snail Littorina saxatilis divergent selection forms strong
    barriers to gene flow, while the role of postzygotic barriers due to selection
    against hybrids remains unclear. High embryo abortion rates in this species could
    indicate the presence of such barriers. Postzygotic barriers might include genetic
    incompatibilities (e.g. Dobzhansky-Muller incompatibilities) but also maladaptation,
    both expected to be most pronounced in contact zones. In addition, embryo abortion
    might reflect physiological stress on females and embryos independent of any genetic
    stress. We examined all embryos of &gt;500 females sampled outside and inside
    contact zones of three populations in Sweden. Females' clutch size ranged from
    0 to 1011 embryos (mean 130±123) and abortion rates varied between 0 and100% (mean
    12%). We described female genotypes by using a hybrid index based on hundreds
    of SNPs differentiated between ecotypes with which we characterised female genotypes.
    We also calculated female SNP heterozygosity and inversion karyotype. Clutch size
    did not vary with female hybrid index and abortion rates were only weakly related
    to hybrid index in two sites but not at all in a third site. No additional variation
    in abortion rate was explained by female SNP heterozygosity, but increased female
    inversion heterozygosity added slightly to increased abortion. Our results show
    only weak and probably biologically insignificant postzygotic barriers contributing
    to ecotype divergence and the high and variable abortion rates were marginally,
    if at all, explained by hybrid index of females.
article_processing_charge: No
author:
- first_name: Kerstin
  full_name: Johannesson, Kerstin
  last_name: Johannesson
- first_name: Zuzanna
  full_name: Zagrodzka, Zuzanna
  last_name: Zagrodzka
- first_name: Rui
  full_name: Faria, Rui
  last_name: Faria
- first_name: Anja M
  full_name: Westram, Anja M
  id: 3C147470-F248-11E8-B48F-1D18A9856A87
  last_name: Westram
  orcid: 0000-0003-1050-4969
- first_name: Roger
  full_name: Butlin, Roger
  last_name: Butlin
citation:
  ama: 'Johannesson K, Zagrodzka Z, Faria R, Westram AM, Butlin R. Data from: Is embryo
    abortion a postzygotic barrier to gene flow between Littorina ecotypes? 2019.
    doi:<a href="https://doi.org/10.5061/DRYAD.TB2RBNZWK">10.5061/DRYAD.TB2RBNZWK</a>'
  apa: 'Johannesson, K., Zagrodzka, Z., Faria, R., Westram, A. M., &#38; Butlin, R.
    (2019). Data from: Is embryo abortion a postzygotic barrier to gene flow between
    Littorina ecotypes? Dryad. <a href="https://doi.org/10.5061/DRYAD.TB2RBNZWK">https://doi.org/10.5061/DRYAD.TB2RBNZWK</a>'
  chicago: 'Johannesson, Kerstin, Zuzanna Zagrodzka, Rui Faria, Anja M Westram, and
    Roger Butlin. “Data from: Is Embryo Abortion a Postzygotic Barrier to Gene Flow
    between Littorina Ecotypes?” Dryad, 2019. <a href="https://doi.org/10.5061/DRYAD.TB2RBNZWK">https://doi.org/10.5061/DRYAD.TB2RBNZWK</a>.'
  ieee: 'K. Johannesson, Z. Zagrodzka, R. Faria, A. M. Westram, and R. Butlin, “Data
    from: Is embryo abortion a postzygotic barrier to gene flow between Littorina
    ecotypes?” Dryad, 2019.'
  ista: 'Johannesson K, Zagrodzka Z, Faria R, Westram AM, Butlin R. 2019. Data from:
    Is embryo abortion a postzygotic barrier to gene flow between Littorina ecotypes?,
    Dryad, <a href="https://doi.org/10.5061/DRYAD.TB2RBNZWK">10.5061/DRYAD.TB2RBNZWK</a>.'
  mla: 'Johannesson, Kerstin, et al. <i>Data from: Is Embryo Abortion a Postzygotic
    Barrier to Gene Flow between Littorina Ecotypes?</i> Dryad, 2019, doi:<a href="https://doi.org/10.5061/DRYAD.TB2RBNZWK">10.5061/DRYAD.TB2RBNZWK</a>.'
  short: K. Johannesson, Z. Zagrodzka, R. Faria, A.M. Westram, R. Butlin, (2019).
date_created: 2023-05-23T16:36:27Z
date_published: 2019-12-02T00:00:00Z
date_updated: 2023-09-06T14:48:57Z
day: '02'
ddc:
- '570'
department:
- _id: NiBa
doi: 10.5061/DRYAD.TB2RBNZWK
license: https://creativecommons.org/publicdomain/zero/1.0/
main_file_link:
- open_access: '1'
  url: https://doi.org/10.5061/dryad.tb2rbnzwk
month: '12'
oa: 1
oa_version: Published Version
publisher: Dryad
related_material:
  record:
  - id: '7205'
    relation: used_in_publication
    status: public
status: public
title: 'Data from: Is embryo abortion a postzygotic barrier to gene flow between Littorina
  ecotypes?'
tmp:
  image: /images/cc_0.png
  legal_code_url: https://creativecommons.org/publicdomain/zero/1.0/legalcode
  name: Creative Commons Public Domain Dedication (CC0 1.0)
  short: CC0 (1.0)
type: research_data_reference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2019'
...
---
_id: '8281'
abstract:
- lang: eng
  text: We review the history of population genetics, starting with its origins a
    century ago from the synthesis between Mendel and Darwin's ideas, through to the
    recent development of sophisticated schemes of inference from sequence data, based
    on the coalescent. We explain the close relation between the coalescent and a
    diffusion process, which we illustrate by their application to understand spatial
    structure. We summarise the powerful methods available for analysis of multiple
    loci, when linkage equilibrium can be assumed, and then discuss approaches to
    the more challenging case, where associations between alleles require that we
    follow genotype, rather than allele, frequencies. Though we can hardly cover the
    whole of population genetics, we give an overview of the current state of the
    subject, and future challenges to it.
article_processing_charge: No
author:
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
- first_name: Alison
  full_name: Etheridge, Alison
  last_name: Etheridge
citation:
  ama: 'Barton NH, Etheridge A. Mathematical models in population genetics. In: Balding
    D, Moltke I, Marioni J, eds. <i>Handbook of Statistical Genomics</i>. 4th ed.
    Wiley; 2019:115-144. doi:<a href="https://doi.org/10.1002/9781119487845.ch4">10.1002/9781119487845.ch4</a>'
  apa: Barton, N. H., &#38; Etheridge, A. (2019). Mathematical models in population
    genetics. In D. Balding, I. Moltke, &#38; J. Marioni (Eds.), <i>Handbook of statistical
    genomics</i> (4th ed., pp. 115–144). Wiley. <a href="https://doi.org/10.1002/9781119487845.ch4">https://doi.org/10.1002/9781119487845.ch4</a>
  chicago: Barton, Nicholas H, and Alison Etheridge. “Mathematical Models in Population
    Genetics.” In <i>Handbook of Statistical Genomics</i>, edited by David Balding,
    Ida Moltke, and John Marioni, 4th ed., 115–44. Wiley, 2019. <a href="https://doi.org/10.1002/9781119487845.ch4">https://doi.org/10.1002/9781119487845.ch4</a>.
  ieee: N. H. Barton and A. Etheridge, “Mathematical models in population genetics,”
    in <i>Handbook of statistical genomics</i>, 4th ed., D. Balding, I. Moltke, and
    J. Marioni, Eds. Wiley, 2019, pp. 115–144.
  ista: 'Barton NH, Etheridge A. 2019.Mathematical models in population genetics.
    In: Handbook of statistical genomics. , 115–144.'
  mla: Barton, Nicholas H., and Alison Etheridge. “Mathematical Models in Population
    Genetics.” <i>Handbook of Statistical Genomics</i>, edited by David Balding et
    al., 4th ed., Wiley, 2019, pp. 115–44, doi:<a href="https://doi.org/10.1002/9781119487845.ch4">10.1002/9781119487845.ch4</a>.
  short: N.H. Barton, A. Etheridge, in:, D. Balding, I. Moltke, J. Marioni (Eds.),
    Handbook of Statistical Genomics, 4th ed., Wiley, 2019, pp. 115–144.
date_created: 2020-08-21T04:25:39Z
date_published: 2019-07-29T00:00:00Z
date_updated: 2023-09-08T11:24:15Z
day: '29'
ddc:
- '576'
department:
- _id: NiBa
doi: 10.1002/9781119487845.ch4
edition: '4'
editor:
- first_name: David
  full_name: Balding, David
  last_name: Balding
- first_name: Ida
  full_name: Moltke, Ida
  last_name: Moltke
- first_name: John
  full_name: Marioni, John
  last_name: Marioni
external_id:
  isi:
  - '000261343000003'
isi: 1
language:
- iso: eng
month: '07'
oa_version: None
page: 115-144
publication: Handbook of statistical genomics
publication_identifier:
  isbn:
  - '9781119429142'
publication_status: published
publisher: Wiley
quality_controlled: '1'
status: public
title: Mathematical models in population genetics
type: book_chapter
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2019'
...
---
_id: '8570'
abstract:
- lang: eng
  text: 'This report presents the results of a friendly competition for formal verification
    of continuous and hybrid systems with linear continuous dynamics. The friendly
    competition took place as part of the workshop Applied Verification for Continuous
    and Hybrid Systems (ARCH) in 2019. In its third edition, seven tools have been
    applied to solve six different benchmark problems in the category for linear continuous
    dynamics (in alphabetical order): CORA, CORA/SX, HyDRA, Hylaa, JuliaReach, SpaceEx,
    and XSpeed. This report is a snapshot of the current landscape of tools and the
    types of benchmarks they are particularly suited for. Due to the diversity of
    problems, we are not ranking tools, yet the presented results provide one of the
    most complete assessments of tools for the safety verification of continuous and
    hybrid systems with linear continuous dynamics up to this date.</jats:p>'
article_processing_charge: No
author:
- first_name: Matthias
  full_name: Althoff, Matthias
  last_name: Althoff
- first_name: Stanley
  full_name: Bak, Stanley
  last_name: Bak
- first_name: Marcelo
  full_name: Forets, Marcelo
  last_name: Forets
- first_name: Goran
  full_name: Frehse, Goran
  last_name: Frehse
- first_name: Niklas
  full_name: Kochdumper, Niklas
  last_name: Kochdumper
- first_name: Rajarshi
  full_name: Ray, Rajarshi
  last_name: Ray
- first_name: Christian
  full_name: Schilling, Christian
  id: 3A2F4DCE-F248-11E8-B48F-1D18A9856A87
  last_name: Schilling
  orcid: 0000-0003-3658-1065
- first_name: Stefan
  full_name: Schupp, Stefan
  last_name: Schupp
citation:
  ama: 'Althoff M, Bak S, Forets M, et al. ARCH-COMP19 Category Report: Continuous
    and hybrid systems with linear continuous dynamics. In: <i>EPiC Series in Computing</i>.
    Vol 61. EasyChair; 2019:14-40. doi:<a href="https://doi.org/10.29007/bj1w">10.29007/bj1w</a>'
  apa: 'Althoff, M., Bak, S., Forets, M., Frehse, G., Kochdumper, N., Ray, R., … Schupp,
    S. (2019). ARCH-COMP19 Category Report: Continuous and hybrid systems with linear
    continuous dynamics. In <i>EPiC Series in Computing</i> (Vol. 61, pp. 14–40).
    Montreal, Canada: EasyChair. <a href="https://doi.org/10.29007/bj1w">https://doi.org/10.29007/bj1w</a>'
  chicago: 'Althoff, Matthias, Stanley Bak, Marcelo Forets, Goran Frehse, Niklas Kochdumper,
    Rajarshi Ray, Christian Schilling, and Stefan Schupp. “ARCH-COMP19 Category Report:
    Continuous and Hybrid Systems with Linear Continuous Dynamics.” In <i>EPiC Series
    in Computing</i>, 61:14–40. EasyChair, 2019. <a href="https://doi.org/10.29007/bj1w">https://doi.org/10.29007/bj1w</a>.'
  ieee: 'M. Althoff <i>et al.</i>, “ARCH-COMP19 Category Report: Continuous and hybrid
    systems with linear continuous dynamics,” in <i>EPiC Series in Computing</i>,
    Montreal, Canada, 2019, vol. 61, pp. 14–40.'
  ista: 'Althoff M, Bak S, Forets M, Frehse G, Kochdumper N, Ray R, Schilling C, Schupp
    S. 2019. ARCH-COMP19 Category Report: Continuous and hybrid systems with linear
    continuous dynamics. EPiC Series in Computing. ARCH: International Workshop on
    Applied Verification on Continuous and Hybrid Systems vol. 61, 14–40.'
  mla: 'Althoff, Matthias, et al. “ARCH-COMP19 Category Report: Continuous and Hybrid
    Systems with Linear Continuous Dynamics.” <i>EPiC Series in Computing</i>, vol.
    61, EasyChair, 2019, pp. 14–40, doi:<a href="https://doi.org/10.29007/bj1w">10.29007/bj1w</a>.'
  short: M. Althoff, S. Bak, M. Forets, G. Frehse, N. Kochdumper, R. Ray, C. Schilling,
    S. Schupp, in:, EPiC Series in Computing, EasyChair, 2019, pp. 14–40.
conference:
  end_date: 2019-04-15
  location: Montreal, Canada
  name: 'ARCH: International Workshop on Applied Verification on Continuous and Hybrid
    Systems'
  start_date: 2019-04-15
date_created: 2020-09-26T14:23:54Z
date_published: 2019-05-25T00:00:00Z
date_updated: 2021-01-12T08:20:05Z
day: '25'
department:
- _id: ToHe
doi: 10.29007/bj1w
intvolume: '        61'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://easychair.org/publications/open/1gbP
month: '05'
oa: 1
oa_version: Published Version
page: 14-40
publication: EPiC Series in Computing
publication_identifier:
  eissn:
  - '23987340'
publication_status: published
publisher: EasyChair
quality_controlled: '1'
status: public
title: 'ARCH-COMP19 Category Report: Continuous and hybrid systems with linear continuous
  dynamics'
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 61
year: '2019'
...
---
_id: '9261'
abstract:
- lang: eng
  text: 'Bending-active structures are able to efficiently produce complex curved
    shapes starting from flat panels. The desired deformation of the panels derives
    from the proper selection of their elastic properties. Optimized panels, called
    FlexMaps, are designed such that, once they are bent and assembled, the resulting
    static equilibrium configuration matches a desired input 3D shape. The FlexMaps
    elastic properties are controlled by locally varying spiraling geometric mesostructures,
    which are optimized in size and shape to match the global curvature (i.e., bending
    requests) of the target shape. The design pipeline starts from a quad mesh representing
    the input 3D shape, which defines the edge size and the total amount of spirals:
    every quad will embed one spiral. Then, an optimization algorithm tunes the geometry
    of the spirals by using a simplified pre-computed rod model. This rod model is
    derived from a non-linear regression algorithm which approximates the non-linear
    behavior of solid FEM spiral models subject to hundreds of load combinations.
    This innovative pipeline has been applied to the project of a lightweight plywood
    pavilion named FlexMaps Pavilion, which is a single-layer piecewise twisted arc
    that fits a bounding box of 3.90x3.96x3.25 meters.'
article_processing_charge: No
author:
- first_name: Francesco
  full_name: Laccone, Francesco
  last_name: Laccone
- first_name: Luigi
  full_name: Malomo, Luigi
  last_name: Malomo
- first_name: Jesus
  full_name: Perez Rodriguez, Jesus
  id: 2DC83906-F248-11E8-B48F-1D18A9856A87
  last_name: Perez Rodriguez
- first_name: Nico
  full_name: Pietroni, Nico
  last_name: Pietroni
- first_name: Federico
  full_name: Ponchio, Federico
  last_name: Ponchio
- first_name: Bernd
  full_name: Bickel, Bernd
  id: 49876194-F248-11E8-B48F-1D18A9856A87
  last_name: Bickel
  orcid: 0000-0001-6511-9385
- first_name: Paolo
  full_name: Cignoni, Paolo
  last_name: Cignoni
citation:
  ama: 'Laccone F, Malomo L, Perez Rodriguez J, et al. FlexMaps Pavilion: A twisted
    arc made of mesostructured flat flexible panels. In: <i>IASS Symposium 2019 -
    60th Anniversary Symposium of the International Association for Shell and Spatial
    Structures; Structural Membranes 2019 - 9th International Conference on Textile
    Composites and Inflatable Structures, FORM and FORCE</i>. International Center
    for Numerical Methods in Engineering; 2019:509-515.'
  apa: 'Laccone, F., Malomo, L., Perez Rodriguez, J., Pietroni, N., Ponchio, F., Bickel,
    B., &#38; Cignoni, P. (2019). FlexMaps Pavilion: A twisted arc made of mesostructured
    flat flexible panels. In <i>IASS Symposium 2019 - 60th Anniversary Symposium of
    the International Association for Shell and Spatial Structures; Structural Membranes
    2019 - 9th International Conference on Textile Composites and Inflatable Structures,
    FORM and FORCE</i> (pp. 509–515). Barcelona, Spain: International Center for Numerical
    Methods in Engineering.'
  chicago: 'Laccone, Francesco, Luigi Malomo, Jesus Perez Rodriguez, Nico Pietroni,
    Federico Ponchio, Bernd Bickel, and Paolo Cignoni. “FlexMaps Pavilion: A Twisted
    Arc Made of Mesostructured Flat Flexible Panels.” In <i>IASS Symposium 2019 -
    60th Anniversary Symposium of the International Association for Shell and Spatial
    Structures; Structural Membranes 2019 - 9th International Conference on Textile
    Composites and Inflatable Structures, FORM and FORCE</i>, 509–15. International
    Center for Numerical Methods in Engineering, 2019.'
  ieee: 'F. Laccone <i>et al.</i>, “FlexMaps Pavilion: A twisted arc made of mesostructured
    flat flexible panels,” in <i>IASS Symposium 2019 - 60th Anniversary Symposium
    of the International Association for Shell and Spatial Structures; Structural
    Membranes 2019 - 9th International Conference on Textile Composites and Inflatable
    Structures, FORM and FORCE</i>, Barcelona, Spain, 2019, pp. 509–515.'
  ista: 'Laccone F, Malomo L, Perez Rodriguez J, Pietroni N, Ponchio F, Bickel B,
    Cignoni P. 2019. FlexMaps Pavilion: A twisted arc made of mesostructured flat
    flexible panels. IASS Symposium 2019 - 60th Anniversary Symposium of the International
    Association for Shell and Spatial Structures; Structural Membranes 2019 - 9th
    International Conference on Textile Composites and Inflatable Structures, FORM
    and FORCE. IASS: International Association for Shell and Spatial Structures, 509–515.'
  mla: 'Laccone, Francesco, et al. “FlexMaps Pavilion: A Twisted Arc Made of Mesostructured
    Flat Flexible Panels.” <i>IASS Symposium 2019 - 60th Anniversary Symposium of
    the International Association for Shell and Spatial Structures; Structural Membranes
    2019 - 9th International Conference on Textile Composites and Inflatable Structures,
    FORM and FORCE</i>, International Center for Numerical Methods in Engineering,
    2019, pp. 509–15.'
  short: F. Laccone, L. Malomo, J. Perez Rodriguez, N. Pietroni, F. Ponchio, B. Bickel,
    P. Cignoni, in:, IASS Symposium 2019 - 60th Anniversary Symposium of the International
    Association for Shell and Spatial Structures; Structural Membranes 2019 - 9th
    International Conference on Textile Composites and Inflatable Structures, FORM
    and FORCE, International Center for Numerical Methods in Engineering, 2019, pp.
    509–515.
conference:
  end_date: 2019-10-10
  location: Barcelona, Spain
  name: 'IASS: International Association for Shell and Spatial Structures'
  start_date: 2019-10-07
date_created: 2021-03-21T23:01:21Z
date_published: 2019-10-10T00:00:00Z
date_updated: 2023-09-08T11:21:54Z
day: '10'
department:
- _id: BeBi
external_id:
  isi:
  - '000563497600059'
isi: 1
language:
- iso: eng
month: '10'
oa_version: None
page: 509-515
publication: IASS Symposium 2019 - 60th Anniversary Symposium of the International
  Association for Shell and Spatial Structures; Structural Membranes 2019 - 9th International
  Conference on Textile Composites and Inflatable Structures, FORM and FORCE
publication_identifier:
  isbn:
  - '9788412110104'
  issn:
  - 2518-6582
publication_status: published
publisher: International Center for Numerical Methods in Engineering
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'FlexMaps Pavilion: A twisted arc made of mesostructured flat flexible panels'
type: conference
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2019'
...
---
_id: '6919'
article_number: eaaw6490
article_processing_charge: No
author:
- first_name: Chao
  full_name: Qi, Chao
  last_name: Qi
- first_name: Giulio Di
  full_name: Minin, Giulio Di
  last_name: Minin
- first_name: Irene
  full_name: Vercellino, Irene
  id: 3ED6AF16-F248-11E8-B48F-1D18A9856A87
  last_name: Vercellino
  orcid: 0000-0001-5618-3449
- first_name: Anton
  full_name: Wutz, Anton
  last_name: Wutz
- first_name: Volodymyr M.
  full_name: Korkhov, Volodymyr M.
  last_name: Korkhov
citation:
  ama: Qi C, Minin GD, Vercellino I, Wutz A, Korkhov VM. Structural basis of sterol
    recognition by human hedgehog receptor PTCH1. <i>Science Advances</i>. 2019;5(9).
    doi:<a href="https://doi.org/10.1126/sciadv.aaw6490">10.1126/sciadv.aaw6490</a>
  apa: Qi, C., Minin, G. D., Vercellino, I., Wutz, A., &#38; Korkhov, V. M. (2019).
    Structural basis of sterol recognition by human hedgehog receptor PTCH1. <i>Science
    Advances</i>. American Association for the Advancement of Science. <a href="https://doi.org/10.1126/sciadv.aaw6490">https://doi.org/10.1126/sciadv.aaw6490</a>
  chicago: Qi, Chao, Giulio Di Minin, Irene Vercellino, Anton Wutz, and Volodymyr
    M. Korkhov. “Structural Basis of Sterol Recognition by Human Hedgehog Receptor
    PTCH1.” <i>Science Advances</i>. American Association for the Advancement of Science,
    2019. <a href="https://doi.org/10.1126/sciadv.aaw6490">https://doi.org/10.1126/sciadv.aaw6490</a>.
  ieee: C. Qi, G. D. Minin, I. Vercellino, A. Wutz, and V. M. Korkhov, “Structural
    basis of sterol recognition by human hedgehog receptor PTCH1,” <i>Science Advances</i>,
    vol. 5, no. 9. American Association for the Advancement of Science, 2019.
  ista: Qi C, Minin GD, Vercellino I, Wutz A, Korkhov VM. 2019. Structural basis of
    sterol recognition by human hedgehog receptor PTCH1. Science Advances. 5(9), eaaw6490.
  mla: Qi, Chao, et al. “Structural Basis of Sterol Recognition by Human Hedgehog
    Receptor PTCH1.” <i>Science Advances</i>, vol. 5, no. 9, eaaw6490, American Association
    for the Advancement of Science, 2019, doi:<a href="https://doi.org/10.1126/sciadv.aaw6490">10.1126/sciadv.aaw6490</a>.
  short: C. Qi, G.D. Minin, I. Vercellino, A. Wutz, V.M. Korkhov, Science Advances
    5 (2019).
date_created: 2019-09-29T22:00:45Z
date_published: 2019-09-18T00:00:00Z
date_updated: 2023-08-30T06:55:31Z
day: '18'
ddc:
- '570'
department:
- _id: LeSa
doi: 10.1126/sciadv.aaw6490
external_id:
  isi:
  - '000491128800062'
file:
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  creator: kschuh
  date_created: 2019-10-02T11:13:54Z
  date_updated: 2020-07-14T12:47:44Z
  file_id: '6928'
  file_name: 2019_AAAS_Qi.pdf
  file_size: 1236101
  relation: main_file
file_date_updated: 2020-07-14T12:47:44Z
has_accepted_license: '1'
intvolume: '         5'
isi: 1
issue: '9'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
publication: Science Advances
publication_identifier:
  eissn:
  - '23752548'
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: Structural basis of sterol recognition by human hedgehog receptor PTCH1
tmp:
  image: /images/cc_by_nc.png
  legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
  short: CC BY-NC (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 5
year: '2019'
...
