--- _id: '14846' abstract: - lang: eng text: Contraction and flow of the actin cell cortex have emerged as a common principle by which cells reorganize their cytoplasm and take shape. However, how these cortical flows interact with adjacent cytoplasmic components, changing their form and localization, and how this affects cytoplasmic organization and cell shape remains unclear. Here we show that in ascidian oocytes, the cooperative activities of cortical actomyosin flows and deformation of the adjacent mitochondria-rich myoplasm drive oocyte cytoplasmic reorganization and shape changes following fertilization. We show that vegetal-directed cortical actomyosin flows, established upon oocyte fertilization, lead to both the accumulation of cortical actin at the vegetal pole of the zygote and compression and local buckling of the adjacent elastic solid-like myoplasm layer due to friction forces generated at their interface. Once cortical flows have ceased, the multiple myoplasm buckles resolve into one larger buckle, which again drives the formation of the contraction pole—a protuberance of the zygote’s vegetal pole where maternal mRNAs accumulate. Thus, our findings reveal a mechanism where cortical actomyosin network flows determine cytoplasmic reorganization and cell shape by deforming adjacent cytoplasmic components through friction forces. acknowledged_ssus: - _id: EM-Fac - _id: Bio - _id: NanoFab acknowledgement: We would like to thank A. McDougall, E. Hannezo and the Heisenberg lab for fruitful discussions and reagents. We also thank E. Munro for the iMyo-YFP and Bra>iMyo-mScarlet constructs. This research was supported by the Scientific Service Units of the Institute of Science and Technology Austria through resources provided by the Electron Microscopy Facility, Imaging and Optics Facility and the Nanofabrication Facility. This work was supported by a Joint Project Grant from the FWF (I 3601-B27). article_processing_charge: Yes (in subscription journal) article_type: original author: - first_name: Silvia full_name: Caballero Mancebo, Silvia id: 2F1E1758-F248-11E8-B48F-1D18A9856A87 last_name: Caballero Mancebo orcid: 0000-0002-5223-3346 - first_name: Rushikesh full_name: Shinde, Rushikesh last_name: Shinde - first_name: Madison full_name: Bolger-Munro, Madison id: 516F03FA-93A3-11EA-A7C5-D6BE3DDC885E last_name: Bolger-Munro orcid: 0000-0002-8176-4824 - first_name: Matilda full_name: Peruzzo, Matilda id: 3F920B30-F248-11E8-B48F-1D18A9856A87 last_name: Peruzzo orcid: 0000-0002-3415-4628 - first_name: Gregory full_name: Szep, Gregory id: 4BFB7762-F248-11E8-B48F-1D18A9856A87 last_name: Szep - first_name: Irene full_name: Steccari, Irene id: 2705C766-9FE2-11EA-B224-C6773DDC885E last_name: Steccari - first_name: David full_name: Labrousse Arias, David id: CD573DF4-9ED3-11E9-9D77-3223E6697425 last_name: Labrousse Arias - first_name: Vanessa full_name: Zheden, Vanessa id: 39C5A68A-F248-11E8-B48F-1D18A9856A87 last_name: Zheden orcid: 0000-0002-9438-4783 - first_name: Jack full_name: Merrin, Jack id: 4515C308-F248-11E8-B48F-1D18A9856A87 last_name: Merrin orcid: 0000-0001-5145-4609 - first_name: Andrew full_name: Callan-Jones, Andrew last_name: Callan-Jones - first_name: Raphaël full_name: Voituriez, Raphaël last_name: Voituriez - first_name: Carl-Philipp J full_name: Heisenberg, Carl-Philipp J id: 39427864-F248-11E8-B48F-1D18A9856A87 last_name: Heisenberg orcid: 0000-0002-0912-4566 citation: ama: Caballero Mancebo S, Shinde R, Bolger-Munro M, et al. Friction forces determine cytoplasmic reorganization and shape changes of ascidian oocytes upon fertilization. Nature Physics. 2024. doi:10.1038/s41567-023-02302-1 apa: Caballero Mancebo, S., Shinde, R., Bolger-Munro, M., Peruzzo, M., Szep, G., Steccari, I., … Heisenberg, C.-P. J. (2024). Friction forces determine cytoplasmic reorganization and shape changes of ascidian oocytes upon fertilization. Nature Physics. Springer Nature. https://doi.org/10.1038/s41567-023-02302-1 chicago: Caballero Mancebo, Silvia, Rushikesh Shinde, Madison Bolger-Munro, Matilda Peruzzo, Gregory Szep, Irene Steccari, David Labrousse Arias, et al. “Friction Forces Determine Cytoplasmic Reorganization and Shape Changes of Ascidian Oocytes upon Fertilization.” Nature Physics. Springer Nature, 2024. https://doi.org/10.1038/s41567-023-02302-1. ieee: S. Caballero Mancebo et al., “Friction forces determine cytoplasmic reorganization and shape changes of ascidian oocytes upon fertilization,” Nature Physics. Springer Nature, 2024. ista: Caballero Mancebo S, Shinde R, Bolger-Munro M, Peruzzo M, Szep G, Steccari I, Labrousse Arias D, Zheden V, Merrin J, Callan-Jones A, Voituriez R, Heisenberg C-PJ. 2024. Friction forces determine cytoplasmic reorganization and shape changes of ascidian oocytes upon fertilization. Nature Physics. mla: Caballero Mancebo, Silvia, et al. “Friction Forces Determine Cytoplasmic Reorganization and Shape Changes of Ascidian Oocytes upon Fertilization.” Nature Physics, Springer Nature, 2024, doi:10.1038/s41567-023-02302-1. short: S. Caballero Mancebo, R. Shinde, M. Bolger-Munro, M. Peruzzo, G. Szep, I. Steccari, D. Labrousse Arias, V. Zheden, J. Merrin, A. Callan-Jones, R. Voituriez, C.-P.J. Heisenberg, Nature Physics (2024). date_created: 2024-01-21T23:00:57Z date_published: 2024-01-09T00:00:00Z date_updated: 2024-03-05T09:33:38Z day: '09' department: - _id: CaHe - _id: JoFi - _id: MiSi - _id: EM-Fac - _id: NanoFab doi: 10.1038/s41567-023-02302-1 has_accepted_license: '1' language: - iso: eng license: https://creativecommons.org/licenses/by/4.0/ main_file_link: - open_access: '1' url: https://doi.org/10.1038/s41567-023-02302-1 month: '01' oa: 1 oa_version: Published Version project: - _id: 2646861A-B435-11E9-9278-68D0E5697425 call_identifier: FWF grant_number: I03601 name: Control of embryonic cleavage pattern publication: Nature Physics publication_identifier: eissn: - 1745-2481 issn: - 1745-2473 publication_status: epub_ahead publisher: Springer Nature quality_controlled: '1' related_material: link: - description: News on ISTA Website relation: press_release url: https://ista.ac.at/en/news/stranger-than-friction-a-force-initiating-life/ scopus_import: '1' status: public title: Friction forces determine cytoplasmic reorganization and shape changes of ascidian oocytes upon fertilization tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 year: '2024' ... --- _id: '14850' abstract: - lang: eng text: Elaborate sexual signals are thought to have evolved and be maintained to serve as honest indicators of signaller quality. One measure of quality is health, which can be affected by parasite infection. Cnemaspis mysoriensis is a diurnal gecko that is often infested with ectoparasites in the wild, and males of this species express visual (coloured gular patches) and chemical (femoral gland secretions) traits that receivers could assess during social interactions. In this paper, we tested whether ectoparasites affect individual health, and whether signal quality is an indicator of ectoparasite levels. In wild lizards, we found that ectoparasite level was negatively correlated with body condition in both sexes. Moreover, some characteristics of both visual and chemical traits in males were strongly associated with ectoparasite levels. Specifically, males with higher ectoparasite levels had yellow gular patches with lower brightness and chroma, and chemical secretions with a lower proportion of aromatic compounds. We then determined whether ectoparasite levels in males influence female behaviour. Using sequential choice trials, wherein females were provided with either the visual or the chemical signals of wild-caught males that varied in ectoparasite level, we found that only chemical secretions evoked an elevated female response towards less parasitised males. Simultaneous choice trials in which females were exposed to the chemical secretions from males that varied in parasite level further confirmed a preference for males with lower parasites loads. Overall, we find that although health (body condition) or ectoparasite load can be honestly advertised through multiple modalities, the parasite-mediated female response is exclusively driven by chemical signals. acknowledgement: "We thank Anuradha Batabyal and Shakilur Kabir for scientific discussions, and help with sampling and colour analyses. We thank Muralidhar and the central LCMS facility of the IISc for their technical support with the GCMS.\r\nResearch funding was provided by the Department of Science and Technology Fund for Improvement of S&T Infrastructure (DST-FIST), the Department of Biotechnology-Indian Institute of Science (DBT-IISc) partnership program and a Science and Engineering Research Board (SERB) grant to M.T. (EMR/2017/002228). Open Access funding provided by Indian Institute of Science. Deposited in PMC for immediate release." article_number: jeb246217 article_processing_charge: Yes (via OA deal) article_type: original author: - first_name: Arka full_name: Pal, Arka id: 6AAB2240-CA9A-11E9-9C1A-D9D1E5697425 last_name: Pal orcid: 0000-0002-4530-8469 - first_name: Mihir full_name: Joshi, Mihir last_name: Joshi - first_name: Maria full_name: Thaker, Maria last_name: Thaker citation: ama: Pal A, Joshi M, Thaker M. Too much information? Males convey parasite levels using more signal modalities than females utilise. Journal of Experimental Biology. 2024;227(1). doi:10.1242/jeb.246217 apa: Pal, A., Joshi, M., & Thaker, M. (2024). Too much information? Males convey parasite levels using more signal modalities than females utilise. Journal of Experimental Biology. The Company of Biologists. https://doi.org/10.1242/jeb.246217 chicago: Pal, Arka, Mihir Joshi, and Maria Thaker. “Too Much Information? Males Convey Parasite Levels Using More Signal Modalities than Females Utilise.” Journal of Experimental Biology. The Company of Biologists, 2024. https://doi.org/10.1242/jeb.246217. ieee: A. Pal, M. Joshi, and M. Thaker, “Too much information? Males convey parasite levels using more signal modalities than females utilise,” Journal of Experimental Biology, vol. 227, no. 1. The Company of Biologists, 2024. ista: Pal A, Joshi M, Thaker M. 2024. Too much information? Males convey parasite levels using more signal modalities than females utilise. Journal of Experimental Biology. 227(1), jeb246217. mla: Pal, Arka, et al. “Too Much Information? Males Convey Parasite Levels Using More Signal Modalities than Females Utilise.” Journal of Experimental Biology, vol. 227, no. 1, jeb246217, The Company of Biologists, 2024, doi:10.1242/jeb.246217. short: A. Pal, M. Joshi, M. Thaker, Journal of Experimental Biology 227 (2024). date_created: 2024-01-22T08:14:49Z date_published: 2024-01-10T00:00:00Z date_updated: 2024-01-23T12:13:08Z day: '10' ddc: - '570' department: - _id: NiBa doi: 10.1242/jeb.246217 external_id: pmid: - '38054353' file: - access_level: open_access checksum: 136325372f6f45abaa62a71e2d23bfb6 content_type: application/pdf creator: dernst date_created: 2024-01-23T12:08:24Z date_updated: 2024-01-23T12:08:24Z file_id: '14877' file_name: 2024_JourExperimBiology_Pal.pdf file_size: 594128 relation: main_file success: 1 file_date_updated: 2024-01-23T12:08:24Z has_accepted_license: '1' intvolume: ' 227' issue: '1' keyword: - Insect Science - Molecular Biology - Animal Science and Zoology - Aquatic Science - Physiology - Ecology - Evolution - Behavior and Systematics language: - iso: eng month: '01' oa: 1 oa_version: Published Version pmid: 1 publication: Journal of Experimental Biology publication_identifier: eissn: - 0022-0949 issn: - 1477-9145 publication_status: published publisher: The Company of Biologists quality_controlled: '1' related_material: link: - relation: software url: https://github.com/arka-pal/Cnemaspis-SexualSignaling status: public title: Too much information? Males convey parasite levels using more signal modalities than females utilise tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 227 year: '2024' ... --- _id: '14851' abstract: - lang: ger text: Die Quantenrotation ist ein spannendes Phänomen, das in vielen verschiedenen Systemen auftritt, von Molekülen und Atomen bis hin zu subatomaren Teilchen wie Neutronen und Protonen. Durch den Einsatz von starken Laserpulsen ist es möglich, die mathematisch anspruchsvolle Topologie der Rotation von Molekülen aufzudecken und topologisch geschützte Zustände zu erzeugen, die unerwartetes Verhalten zeigen. Diese Entdeckungen könnten Auswirkungen auf die Molekülphysik und physikalische Chemie haben und die Entwicklung neuer Technologien ermöglichen. Die Verbindung von Quantenrotation und Topologie stellt ein aufregendes, interdisziplinäres Forschungsfeld dar und bietet neue Wege zur Kontrolle und Nutzung von quantenmechanischen Phänomenen. article_processing_charge: Yes (via OA deal) article_type: original author: - first_name: Volker full_name: Karle, Volker id: D7C012AE-D7ED-11E9-95E8-1EC5E5697425 last_name: Karle orcid: 0000-0002-6963-0129 - first_name: Mikhail full_name: Lemeshko, Mikhail id: 37CB05FA-F248-11E8-B48F-1D18A9856A87 last_name: Lemeshko orcid: 0000-0002-6990-7802 citation: ama: Karle V, Lemeshko M. Die faszinierende Topologie rotierender Quanten. Physik in unserer Zeit. 2024;55(1):28-33. doi:10.1002/piuz.202301690 apa: Karle, V., & Lemeshko, M. (2024). Die faszinierende Topologie rotierender Quanten. Physik in unserer Zeit. Wiley. https://doi.org/10.1002/piuz.202301690 chicago: Karle, Volker, and Mikhail Lemeshko. “Die faszinierende Topologie rotierender Quanten.” Physik in unserer Zeit. Wiley, 2024. https://doi.org/10.1002/piuz.202301690. ieee: V. Karle and M. Lemeshko, “Die faszinierende Topologie rotierender Quanten,” Physik in unserer Zeit, vol. 55, no. 1. Wiley, pp. 28–33, 2024. ista: Karle V, Lemeshko M. 2024. Die faszinierende Topologie rotierender Quanten. Physik in unserer Zeit. 55(1), 28–33. mla: Karle, Volker, and Mikhail Lemeshko. “Die faszinierende Topologie rotierender Quanten.” Physik in unserer Zeit, vol. 55, no. 1, Wiley, 2024, pp. 28–33, doi:10.1002/piuz.202301690. short: V. Karle, M. Lemeshko, Physik in unserer Zeit 55 (2024) 28–33. date_created: 2024-01-22T08:19:36Z date_published: 2024-01-01T00:00:00Z date_updated: 2024-02-15T14:29:04Z day: '01' ddc: - '530' department: - _id: MiLe doi: 10.1002/piuz.202301690 file: - access_level: open_access checksum: 3051dadcf9bc57da97e36b647c596ab1 content_type: application/pdf creator: dernst date_created: 2024-01-23T12:18:07Z date_updated: 2024-01-23T12:18:07Z file_id: '14878' file_name: 2024_PhysikZeit_Karle.pdf file_size: 1155244 relation: main_file success: 1 file_date_updated: 2024-01-23T12:18:07Z has_accepted_license: '1' intvolume: ' 55' issue: '1' keyword: - General Earth and Planetary Sciences - General Environmental Science language: - iso: ger month: '01' oa: 1 oa_version: Published Version page: 28-33 publication: Physik in unserer Zeit publication_identifier: eissn: - 1521-3943 issn: - 0031-9252 publication_status: published publisher: Wiley quality_controlled: '1' status: public title: Die faszinierende Topologie rotierender Quanten tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87 volume: 55 year: '2024' ... --- _id: '14852' abstract: - lang: eng text: The physical conditions giving rise to high escape fractions of ionizing radiation (LyC fesc) in star-forming galaxies – most likely protagonists of cosmic reionization – are not yet fully understood. Using the VLT/MUSE observations of ∼1400 Ly α emitters at 2.9 < z < 6.7, we compare stacked rest-frame UV spectra of candidates for LyC leakers and non-leakers selected based on their Ly α profiles. We find that the stacks of potential LyC leakers, i.e. galaxies with narrow, symmetric Ly α profiles with small peak separation, generally show (i) strong nebular O iii]λ1666, [Si iii]λ1883, and [C iii]λ1907 +C iii]λ1909 emission, indicating a high-ionization state of the interstellar medium (ISM); (ii) high equivalent widths of He iiλ1640 (∼1 − 3 Å), suggesting the presence of hard ionizing radiation fields; (iii) Si ii*λ1533 emission, revealing substantial amounts of neutral hydrogen off the line of sight; (iv) high C ivλλ1548,1550 to [C iii]λ1907 +C iii]λ1909 ratios (C iv/C iii] ≳0.75) , signalling the presence of low column density channels in the ISM. In contrast, the stacks with broad, asymmetric Ly α profiles with large peak separation show weak nebular emission lines, low He iiλ1640 equivalent widths (≲1 Å), and low C iv/C iii] (≲0.25), implying low-ionization states and high-neutral hydrogen column densities. Our results suggest that C iv/C iii] might be sensitive to the physical conditions that govern LyC photon escape, providing a promising tool for identification of ionizing sources among star-forming galaxies in the epoch of reionization. acknowledgement: 'We thank the anonymous referee for the constructive feedback that helped to improve the manuscript. We thank Michael Maseda, Daniel Schaerer, Charlotte Simmonds, and Rashmi Gottumukkala for useful comments and productive discussions. We also thank the organizers and participants of the 24th MUSE Science Busy Week in Leiden. IGK acknowledges an Excellence Master Fellowship granted by the Faculty of Science of the University of Geneva. This work has received funding from the Swiss State Secretariat for Education, Research and Innovation (SERI) under contract number MB22.00072, as well as from the Swiss National Science Foundation (SNSF) through project grant number 200020_207349 and SNSF Professorship grant number 190079. The Cosmic Dawn Center (DAWN) is funded by the Danish National Research Foundation under grant number 140. This paper is based on observations collected at the European Organisation for Astronomical Research in the Southern Hemisphere under ESO programmes 094.A-0289(B), 095.A-0010(A), 096.A-0045(A), 096.A-0045(B), 094.A-0205, 095.A-0240, 096.A-0090, 097.A-0160, and 098.A-0017. We made extensive use of several open-source software packages and we are thankful to the respective authors for sharing their work: NUMPY (Harris et al. 2020), ASTROPY (Astropy Collaboration 2022), MATPLOTLIB (Hunter 2007), IPYTHON (Perez & Granger 2007), and TOPCAT (Taylor 2005).' article_processing_charge: Yes (in subscription journal) article_type: original arxiv: 1 author: - first_name: Ivan full_name: Kramarenko, Ivan id: 9a9394cb-3200-11ee-973b-f5ba2a8b16e4 last_name: Kramarenko - first_name: J full_name: Kerutt, J last_name: Kerutt - first_name: A full_name: Verhamme, A last_name: Verhamme - first_name: P A full_name: Oesch, P A last_name: Oesch - first_name: L full_name: Barrufet, L last_name: Barrufet - first_name: Jorryt J full_name: Matthee, Jorryt J id: 7439a258-f3c0-11ec-9501-9df22fe06720 last_name: Matthee orcid: 0000-0003-2871-127X - first_name: H full_name: Kusakabe, H last_name: Kusakabe - first_name: I full_name: Goovaerts, I last_name: Goovaerts - first_name: T T full_name: Thai, T T last_name: Thai citation: ama: Kramarenko I, Kerutt J, Verhamme A, et al. Linking UV spectral properties of MUSE Ly α emitters at z ≳ 3 to Lyman continuum escape. Monthly Notices of the Royal Astronomical Society. 2024;527(4):9853-9871. doi:10.1093/mnras/stad3853 apa: Kramarenko, I., Kerutt, J., Verhamme, A., Oesch, P. A., Barrufet, L., Matthee, J. J., … Thai, T. T. (2024). Linking UV spectral properties of MUSE Ly α emitters at z ≳ 3 to Lyman continuum escape. Monthly Notices of the Royal Astronomical Society. Oxford University Press. https://doi.org/10.1093/mnras/stad3853 chicago: Kramarenko, Ivan, J Kerutt, A Verhamme, P A Oesch, L Barrufet, Jorryt J Matthee, H Kusakabe, I Goovaerts, and T T Thai. “Linking UV Spectral Properties of MUSE Ly α Emitters at z ≳ 3 to Lyman Continuum Escape.” Monthly Notices of the Royal Astronomical Society. Oxford University Press, 2024. https://doi.org/10.1093/mnras/stad3853. ieee: I. Kramarenko et al., “Linking UV spectral properties of MUSE Ly α emitters at z ≳ 3 to Lyman continuum escape,” Monthly Notices of the Royal Astronomical Society, vol. 527, no. 4. Oxford University Press, pp. 9853–9871, 2024. ista: Kramarenko I, Kerutt J, Verhamme A, Oesch PA, Barrufet L, Matthee JJ, Kusakabe H, Goovaerts I, Thai TT. 2024. Linking UV spectral properties of MUSE Ly α emitters at z ≳ 3 to Lyman continuum escape. Monthly Notices of the Royal Astronomical Society. 527(4), 9853–9871. mla: Kramarenko, Ivan, et al. “Linking UV Spectral Properties of MUSE Ly α Emitters at z ≳ 3 to Lyman Continuum Escape.” Monthly Notices of the Royal Astronomical Society, vol. 527, no. 4, Oxford University Press, 2024, pp. 9853–71, doi:10.1093/mnras/stad3853. short: I. Kramarenko, J. Kerutt, A. Verhamme, P.A. Oesch, L. Barrufet, J.J. Matthee, H. Kusakabe, I. Goovaerts, T.T. Thai, Monthly Notices of the Royal Astronomical Society 527 (2024) 9853–9871. date_created: 2024-01-22T08:22:17Z date_published: 2024-02-01T00:00:00Z date_updated: 2024-01-23T12:33:50Z day: '01' ddc: - '520' department: - _id: GradSch - _id: JoMa doi: 10.1093/mnras/stad3853 external_id: arxiv: - '2305.07044' file: - access_level: open_access checksum: 9d02df4035c4951cf63dee0db1e462e9 content_type: application/pdf creator: dernst date_created: 2024-01-23T12:30:45Z date_updated: 2024-01-23T12:30:45Z file_id: '14879' file_name: 2024_MNAstronomSoc_Kramarenko.pdf file_size: 4521738 relation: main_file success: 1 file_date_updated: 2024-01-23T12:30:45Z has_accepted_license: '1' intvolume: ' 527' issue: '4' keyword: - Space and Planetary Science - Astronomy and Astrophysics language: - iso: eng month: '02' oa: 1 oa_version: Published Version page: 9853-9871 publication: Monthly Notices of the Royal Astronomical Society publication_identifier: eissn: - 1365-2966 issn: - 0035-8711 publication_status: published publisher: Oxford University Press quality_controlled: '1' status: public title: Linking UV spectral properties of MUSE Ly α emitters at z ≳ 3 to Lyman continuum escape tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 527 year: '2024' ... --- _id: '14884' abstract: - lang: eng text: We perform a stochastic homogenization analysis for composite materials exhibiting a random microstructure. Under the assumptions of stationarity and ergodicity, we characterize the Gamma-limit of a micromagnetic energy functional defined on magnetizations taking value in the unit sphere and including both symmetric and antisymmetric exchange contributions. This Gamma-limit corresponds to a micromagnetic energy functional with homogeneous coefficients. We provide explicit formulas for the effective magnetic properties of the composite material in terms of homogenization correctors. Additionally, the variational analysis of the two exchange energy terms is performed in the more general setting of functionals defined on manifold-valued maps with Sobolev regularity, in the case in which the target manifold is a bounded, orientable smooth surface with tubular neighborhood of uniform thickness. Eventually, we present an explicit characterization of minimizers of the effective exchange in the case of magnetic multilayers, providing quantitative evidence of Dzyaloshinskii’s predictions on the emergence of helical structures in composite ferromagnetic materials with stochastic microstructure. acknowledgement: All authors acknowledge support of the Austrian Science Fund (FWF) through the SFB project F65. The research of E. Davoli and L. D’Elia has additionally been supported by the FWF through grants V662, Y1292, and P35359, as well as from OeAD through the WTZ grant CZ09/2023. article_number: '30' article_processing_charge: No article_type: original arxiv: 1 author: - first_name: Elisa full_name: Davoli, Elisa last_name: Davoli - first_name: Lorenza full_name: D’Elia, Lorenza last_name: D’Elia - first_name: Jonas full_name: Ingmanns, Jonas id: 71523d30-15b2-11ec-abd3-f80aa909d6b0 last_name: Ingmanns citation: ama: Davoli E, D’Elia L, Ingmanns J. Stochastic homogenization of micromagnetic energies and emergence of magnetic skyrmions. Journal of Nonlinear Science. 2024;34(2). doi:10.1007/s00332-023-10005-3 apa: Davoli, E., D’Elia, L., & Ingmanns, J. (2024). Stochastic homogenization of micromagnetic energies and emergence of magnetic skyrmions. Journal of Nonlinear Science. Springer Nature. https://doi.org/10.1007/s00332-023-10005-3 chicago: Davoli, Elisa, Lorenza D’Elia, and Jonas Ingmanns. “Stochastic Homogenization of Micromagnetic Energies and Emergence of Magnetic Skyrmions.” Journal of Nonlinear Science. Springer Nature, 2024. https://doi.org/10.1007/s00332-023-10005-3. ieee: E. Davoli, L. D’Elia, and J. Ingmanns, “Stochastic homogenization of micromagnetic energies and emergence of magnetic skyrmions,” Journal of Nonlinear Science, vol. 34, no. 2. Springer Nature, 2024. ista: Davoli E, D’Elia L, Ingmanns J. 2024. Stochastic homogenization of micromagnetic energies and emergence of magnetic skyrmions. Journal of Nonlinear Science. 34(2), 30. mla: Davoli, Elisa, et al. “Stochastic Homogenization of Micromagnetic Energies and Emergence of Magnetic Skyrmions.” Journal of Nonlinear Science, vol. 34, no. 2, 30, Springer Nature, 2024, doi:10.1007/s00332-023-10005-3. short: E. Davoli, L. D’Elia, J. Ingmanns, Journal of Nonlinear Science 34 (2024). date_created: 2024-01-28T23:01:42Z date_published: 2024-01-23T00:00:00Z date_updated: 2024-02-05T08:54:44Z day: '23' department: - _id: JuFi doi: 10.1007/s00332-023-10005-3 external_id: arxiv: - '2306.05151' intvolume: ' 34' issue: '2' language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.48550/arXiv.2306.05151 month: '01' oa: 1 oa_version: Preprint project: - _id: fc31cba2-9c52-11eb-aca3-ff467d239cd2 grant_number: F6504 name: Taming Complexity in Partial Differential Systems publication: Journal of Nonlinear Science publication_identifier: eissn: - 1432-1467 issn: - 0938-8974 publication_status: epub_ahead publisher: Springer Nature quality_controlled: '1' scopus_import: '1' status: public title: Stochastic homogenization of micromagnetic energies and emergence of magnetic skyrmions type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 34 year: '2024' ... --- _id: '14885' abstract: - lang: eng text: The near-surface boundary layer can mediate the response of mountain glaciers to external climate, cooling the overlying air and promoting a density-driven glacier wind. The fundamental processes are conceptually well understood, though the magnitudes of cooling and presence of glacier winds are poorly quantified in space and time, increasing the forcing uncertainty for melt models. We utilize a new data set of on-glacier meteorological measurements on three neighboring glaciers in the Swiss Alps to explore their distinct response to regional climate under the extreme 2022 summer. We find that synoptic wind origins and local terrain modifications, not only glacier size, play an important role in the ability of a glacier to cool the near-surface air. Warm air intrusions from valley or synoptically-driven winds onto the glacier can occur between ∼19% and 64% of the time and contribute between 3% and 81% of the total sensible heat flux to the surface during warm afternoon hours, depending on the fetch of the glacier flowline and its susceptibility to boundary layer erosion. In the context of extreme summer warmth, indicative of future conditions, the boundary layer cooling (up to 6.5°C cooler than its surroundings) and resultant katabatic wind flow are highly heterogeneous between the study glaciers, highlighting the complex and likely non-linear response of glaciers to an uncertain future. acknowledgement: This project has received funding from the European Union's Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No. 101026058. The authors acknowledge the invaluable field assistance of Marta Corrà, Achille Jouberton, Marin Kneib, Stefan Fugger, Celine Ducret and Alexander Groos. The authors would also like to thank Luca Carturan for advice regarding AWS setup and maintenance and Simone Fatichi for provision and support in the use of the Tethys-Chloris model. Open access funding provided by ETH-Bereich Forschungsanstalten. article_number: e2023JD040214 article_processing_charge: Yes (in subscription journal) article_type: original author: - first_name: Thomas full_name: Shaw, Thomas id: 3caa3f91-1f03-11ee-96ce-e0e553054d6e last_name: Shaw orcid: 0000-0001-7640-6152 - first_name: Pascal full_name: Buri, Pascal id: 317987aa-9421-11ee-ac5a-b941b041abba last_name: Buri - first_name: Michael full_name: Mccarthy, Michael id: 22a2674a-61ce-11ee-94b5-d18813baf16f last_name: Mccarthy - first_name: Evan S. full_name: Miles, Evan S. last_name: Miles - first_name: Francesca full_name: Pellicciotti, Francesca id: b28f055a-81ea-11ed-b70c-a9fe7f7b0e70 last_name: Pellicciotti orcid: 0000-0002-5554-8087 citation: ama: 'Shaw T, Buri P, McCarthy M, Miles ES, Pellicciotti F. Local controls on near-surface glacier cooling under warm atmospheric conditions. Journal of Geophysical Research: Atmospheres. 2024;129(2). doi:10.1029/2023JD040214' apa: 'Shaw, T., Buri, P., McCarthy, M., Miles, E. S., & Pellicciotti, F. (2024). Local controls on near-surface glacier cooling under warm atmospheric conditions. Journal of Geophysical Research: Atmospheres. Wiley. https://doi.org/10.1029/2023JD040214' chicago: 'Shaw, Thomas, Pascal Buri, Michael McCarthy, Evan S. Miles, and Francesca Pellicciotti. “Local Controls on Near-Surface Glacier Cooling under Warm Atmospheric Conditions.” Journal of Geophysical Research: Atmospheres. Wiley, 2024. https://doi.org/10.1029/2023JD040214.' ieee: 'T. Shaw, P. Buri, M. McCarthy, E. S. Miles, and F. Pellicciotti, “Local controls on near-surface glacier cooling under warm atmospheric conditions,” Journal of Geophysical Research: Atmospheres, vol. 129, no. 2. Wiley, 2024.' ista: 'Shaw T, Buri P, McCarthy M, Miles ES, Pellicciotti F. 2024. Local controls on near-surface glacier cooling under warm atmospheric conditions. Journal of Geophysical Research: Atmospheres. 129(2), e2023JD040214.' mla: 'Shaw, Thomas, et al. “Local Controls on Near-Surface Glacier Cooling under Warm Atmospheric Conditions.” Journal of Geophysical Research: Atmospheres, vol. 129, no. 2, e2023JD040214, Wiley, 2024, doi:10.1029/2023JD040214.' short: 'T. Shaw, P. Buri, M. McCarthy, E.S. Miles, F. Pellicciotti, Journal of Geophysical Research: Atmospheres 129 (2024).' date_created: 2024-01-28T23:01:42Z date_published: 2024-01-28T00:00:00Z date_updated: 2024-02-06T08:44:02Z day: '28' ddc: - '550' department: - _id: FrPe doi: 10.1029/2023JD040214 file: - access_level: open_access checksum: cad5b93caadb40c14e5faedc34f7bba7 content_type: application/pdf creator: dernst date_created: 2024-02-06T08:38:27Z date_updated: 2024-02-06T08:38:27Z file_id: '14943' file_name: 2024_JGRAtmospheres_Shaw.pdf file_size: 7481087 relation: main_file success: 1 file_date_updated: 2024-02-06T08:38:27Z has_accepted_license: '1' intvolume: ' 129' issue: '2' language: - iso: eng month: '01' oa: 1 oa_version: Published Version publication: 'Journal of Geophysical Research: Atmospheres' publication_identifier: eissn: - 2169-8996 issn: - 2169-897X publication_status: published publisher: Wiley quality_controlled: '1' related_material: record: - id: '14919' relation: research_data status: public scopus_import: '1' status: public title: Local controls on near-surface glacier cooling under warm atmospheric conditions tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 129 year: '2024' ... --- _id: '14886' abstract: - lang: eng text: It is a basic principle that an effect cannot come before the cause. Dispersive relations that follow from this fundamental fact have proven to be an indispensable tool in physics and engineering. They are most powerful in the domain of linear response where they are known as Kramers-Kronig relations. However, when it comes to nonlinear phenomena the implications of causality are much less explored, apart from several notable exceptions. Here in this paper we demonstrate how to apply the dispersive formalism to analyze the ultrafast nonlinear response in the context of the paradigmatic nonlinear Kerr effect. We find that the requirement of causality introduces a noticeable effect even under assumption that Kerr effect is mediated by quasi-instantaneous off-resonant electronic hyperpolarizability. We confirm this by experimentally measuring the time-resolved Kerr dynamics in GaAs by means of a hybrid pump-probe Mach-Zehnder interferometer and demonstrate the presence of an intrinsic lagging between amplitude and phase responses as predicted by dispersive analysis. Our results describe a general property of the time-resolved nonlinear processes thereby highlighting the importance of accounting for dispersive effects in the nonlinear optical processes involving ultrashort pulses. acknowledgement: The work was supported by the Institute of Science and Technology Austria (ISTA). We thank Prof. John M. Dudley, Dr. Ugur Sezer, and Dr. Artem Volosniev for valuable discussions. article_number: '013042' article_processing_charge: Yes article_type: original author: - first_name: Dusan full_name: Lorenc, Dusan id: 40D8A3E6-F248-11E8-B48F-1D18A9856A87 last_name: Lorenc - first_name: Zhanybek full_name: Alpichshev, Zhanybek id: 45E67A2A-F248-11E8-B48F-1D18A9856A87 last_name: Alpichshev orcid: 0000-0002-7183-5203 citation: ama: 'Lorenc D, Alpichshev Z. Dispersive effects in ultrafast nonlinear phenomena: The case of optical Kerr effect. Physical Review Research. 2024;6(1). doi:10.1103/PhysRevResearch.6.013042' apa: 'Lorenc, D., & Alpichshev, Z. (2024). Dispersive effects in ultrafast nonlinear phenomena: The case of optical Kerr effect. Physical Review Research. American Physical Society. https://doi.org/10.1103/PhysRevResearch.6.013042' chicago: 'Lorenc, Dusan, and Zhanybek Alpichshev. “Dispersive Effects in Ultrafast Nonlinear Phenomena: The Case of Optical Kerr Effect.” Physical Review Research. American Physical Society, 2024. https://doi.org/10.1103/PhysRevResearch.6.013042.' ieee: 'D. Lorenc and Z. Alpichshev, “Dispersive effects in ultrafast nonlinear phenomena: The case of optical Kerr effect,” Physical Review Research, vol. 6, no. 1. American Physical Society, 2024.' ista: 'Lorenc D, Alpichshev Z. 2024. Dispersive effects in ultrafast nonlinear phenomena: The case of optical Kerr effect. Physical Review Research. 6(1), 013042.' mla: 'Lorenc, Dusan, and Zhanybek Alpichshev. “Dispersive Effects in Ultrafast Nonlinear Phenomena: The Case of Optical Kerr Effect.” Physical Review Research, vol. 6, no. 1, 013042, American Physical Society, 2024, doi:10.1103/PhysRevResearch.6.013042.' short: D. Lorenc, Z. Alpichshev, Physical Review Research 6 (2024). date_created: 2024-01-28T23:01:42Z date_published: 2024-01-11T00:00:00Z date_updated: 2024-01-31T12:01:16Z day: '11' ddc: - '530' department: - _id: ZhAl doi: 10.1103/PhysRevResearch.6.013042 file: - access_level: open_access checksum: 42d58f93ae74e7f2c4de058ef75ff8b2 content_type: application/pdf creator: dernst date_created: 2024-01-31T11:59:30Z date_updated: 2024-01-31T11:59:30Z file_id: '14918' file_name: 2024_PhysicalReviewResearch_Lorenc.pdf file_size: 2863627 relation: main_file success: 1 file_date_updated: 2024-01-31T11:59:30Z has_accepted_license: '1' intvolume: ' 6' issue: '1' language: - iso: eng month: '01' oa: 1 oa_version: Published Version publication: Physical Review Research publication_identifier: eissn: - 2643-1564 publication_status: published publisher: American Physical Society quality_controlled: '1' scopus_import: '1' status: public title: 'Dispersive effects in ultrafast nonlinear phenomena: The case of optical Kerr effect' tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 6 year: '2024' ... --- _id: '14887' abstract: - lang: eng text: 'Episodic memories are encoded by experience-activated neuronal ensembles that remain necessary and sufficient for recall. However, the temporal evolution of memory engrams after initial encoding is unclear. In this study, we employed computational and experimental approaches to examine how the neural composition and selectivity of engrams change with memory consolidation. Our spiking neural network model yielded testable predictions: memories transition from unselective to selective as neurons drop out of and drop into engrams; inhibitory activity during recall is essential for memory selectivity; and inhibitory synaptic plasticity during memory consolidation is critical for engrams to become selective. Using activity-dependent labeling, longitudinal calcium imaging and a combination of optogenetic and chemogenetic manipulations in mouse dentate gyrus, we conducted contextual fear conditioning experiments that supported our model’s predictions. Our results reveal that memory engrams are dynamic and that changes in engram composition mediated by inhibitory plasticity are crucial for the emergence of memory selectivity.' acknowledgement: We thank S. Erisken from Inscopix for helping us establish in vivo one-photon calcium imaging for this work. We thank K. Su at Tsinghua University for assistance with this work. This work was funded by the President’s PhD Scholarship from Imperial College London (D.F.T.), the Wellcome Trust (225412/Z/22/Z) (S.S.), the Biotechnology and Biological Sciences Research Council (BB/N013956/1 and BB/N019008/1) (C.C.), the Wellcome Trust (200790/Z/16/Z) (C.C.), the Simons Foundation (564408) (C.C.) and the Engineering and Physical Sciences Research Council (EP/R035806/1) (CC). The School of Life Sciences and the IDG/McGovern Institute for Brain Research supported Y.Z. The Warren Alpert Distinguished Scholar Award and National Institutes of Health 1K99NS125131-01 supported D.S.R. article_processing_charge: Yes (in subscription journal) article_type: original author: - first_name: Douglas full_name: Feitosa Tomé, Douglas id: 0eed2d40-3d48-11ec-8d38-f789cc2e40b2 last_name: Feitosa Tomé - first_name: Ying full_name: Zhang, Ying last_name: Zhang - first_name: Tomomi full_name: Aida, Tomomi last_name: Aida - first_name: Olivia full_name: Mosto, Olivia last_name: Mosto - first_name: Yifeng full_name: Lu, Yifeng last_name: Lu - first_name: Mandy full_name: Chen, Mandy last_name: Chen - first_name: Sadra full_name: Sadeh, Sadra last_name: Sadeh - first_name: Dheeraj S. full_name: Roy, Dheeraj S. last_name: Roy - first_name: Claudia full_name: Clopath, Claudia last_name: Clopath citation: ama: Feitosa Tomé D, Zhang Y, Aida T, et al. Dynamic and selective engrams emerge with memory consolidation. Nature Neuroscience. 2024. doi:10.1038/s41593-023-01551-w apa: Feitosa Tomé, D., Zhang, Y., Aida, T., Mosto, O., Lu, Y., Chen, M., … Clopath, C. (2024). Dynamic and selective engrams emerge with memory consolidation. Nature Neuroscience. Springer Nature. https://doi.org/10.1038/s41593-023-01551-w chicago: Feitosa Tomé, Douglas, Ying Zhang, Tomomi Aida, Olivia Mosto, Yifeng Lu, Mandy Chen, Sadra Sadeh, Dheeraj S. Roy, and Claudia Clopath. “Dynamic and Selective Engrams Emerge with Memory Consolidation.” Nature Neuroscience. Springer Nature, 2024. https://doi.org/10.1038/s41593-023-01551-w. ieee: D. Feitosa Tomé et al., “Dynamic and selective engrams emerge with memory consolidation,” Nature Neuroscience. Springer Nature, 2024. ista: Feitosa Tomé D, Zhang Y, Aida T, Mosto O, Lu Y, Chen M, Sadeh S, Roy DS, Clopath C. 2024. Dynamic and selective engrams emerge with memory consolidation. Nature Neuroscience. mla: Feitosa Tomé, Douglas, et al. “Dynamic and Selective Engrams Emerge with Memory Consolidation.” Nature Neuroscience, Springer Nature, 2024, doi:10.1038/s41593-023-01551-w. short: D. Feitosa Tomé, Y. Zhang, T. Aida, O. Mosto, Y. Lu, M. Chen, S. Sadeh, D.S. Roy, C. Clopath, Nature Neuroscience (2024). date_created: 2024-01-28T23:01:43Z date_published: 2024-01-19T00:00:00Z date_updated: 2024-01-29T09:22:00Z day: '19' department: - _id: TiVo doi: 10.1038/s41593-023-01551-w external_id: isi: - '001145442300001' isi: 1 language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.1038/s41593-023-01551-w month: '01' oa: 1 oa_version: Published Version publication: Nature Neuroscience publication_identifier: eissn: - 1546-1726 issn: - 1097-6256 publication_status: epub_ahead publisher: Springer Nature quality_controlled: '1' related_material: record: - id: '14892' relation: research_data status: public scopus_import: '1' status: public title: Dynamic and selective engrams emerge with memory consolidation type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 year: '2024' ... --- _id: '14888' abstract: - lang: eng text: 'A face in a curve arrangement is called popular if it is bounded by the same curve multiple times. Motivated by the automatic generation of curved nonogram puzzles, we investigate possibilities to eliminate the popular faces in an arrangement by inserting a single additional curve. This turns out to be NP-hard; however, it becomes tractable when the number of popular faces is small: We present a probabilistic FPT-approach in the number of popular faces.' acknowledgement: 'This work was initiated at the 16th European Research Week on Geometric Graphs in Strobl in 2019. A.W. is supported by the Austrian Science Fund (FWF): W1230. S.T. has been funded by the Vienna Science and Technology Fund (WWTF) [10.47379/ICT19035]. A preliminary version of this work has been presented at the 38th European Workshop on Computational Geometry (EuroCG 2022) in Perugia [9]. A full version of this paper, which includes appendices but is otherwise identical, is available as a technical report [10].' alternative_title: - LNCS article_processing_charge: No arxiv: 1 author: - first_name: Phoebe full_name: De Nooijer, Phoebe last_name: De Nooijer - first_name: Soeren full_name: Terziadis, Soeren last_name: Terziadis - first_name: Alexandra full_name: Weinberger, Alexandra last_name: Weinberger - first_name: Zuzana full_name: Masárová, Zuzana id: 45CFE238-F248-11E8-B48F-1D18A9856A87 last_name: Masárová orcid: 0000-0002-6660-1322 - first_name: Tamara full_name: Mchedlidze, Tamara last_name: Mchedlidze - first_name: Maarten full_name: Löffler, Maarten last_name: Löffler - first_name: Günter full_name: Rote, Günter last_name: Rote citation: ama: 'De Nooijer P, Terziadis S, Weinberger A, et al. Removing popular faces in curve arrangements. In: 31st International Symposium on Graph Drawing and Network Visualization. Vol 14466. Springer Nature; 2024:18-33. doi:10.1007/978-3-031-49275-4_2' apa: 'De Nooijer, P., Terziadis, S., Weinberger, A., Masárová, Z., Mchedlidze, T., Löffler, M., & Rote, G. (2024). Removing popular faces in curve arrangements. In 31st International Symposium on Graph Drawing and Network Visualization (Vol. 14466, pp. 18–33). Isola delle Femmine, Palermo, Italy: Springer Nature. https://doi.org/10.1007/978-3-031-49275-4_2' chicago: De Nooijer, Phoebe, Soeren Terziadis, Alexandra Weinberger, Zuzana Masárová, Tamara Mchedlidze, Maarten Löffler, and Günter Rote. “Removing Popular Faces in Curve Arrangements.” In 31st International Symposium on Graph Drawing and Network Visualization, 14466:18–33. Springer Nature, 2024. https://doi.org/10.1007/978-3-031-49275-4_2. ieee: P. De Nooijer et al., “Removing popular faces in curve arrangements,” in 31st International Symposium on Graph Drawing and Network Visualization, Isola delle Femmine, Palermo, Italy, 2024, vol. 14466, pp. 18–33. ista: 'De Nooijer P, Terziadis S, Weinberger A, Masárová Z, Mchedlidze T, Löffler M, Rote G. 2024. Removing popular faces in curve arrangements. 31st International Symposium on Graph Drawing and Network Visualization. GD: Graph Drawing and Network Visualization, LNCS, vol. 14466, 18–33.' mla: De Nooijer, Phoebe, et al. “Removing Popular Faces in Curve Arrangements.” 31st International Symposium on Graph Drawing and Network Visualization, vol. 14466, Springer Nature, 2024, pp. 18–33, doi:10.1007/978-3-031-49275-4_2. short: P. De Nooijer, S. Terziadis, A. Weinberger, Z. Masárová, T. Mchedlidze, M. Löffler, G. Rote, in:, 31st International Symposium on Graph Drawing and Network Visualization, Springer Nature, 2024, pp. 18–33. conference: end_date: 2023-09-22 location: Isola delle Femmine, Palermo, Italy name: 'GD: Graph Drawing and Network Visualization' start_date: 2023-09-20 date_created: 2024-01-28T23:01:43Z date_published: 2024-01-06T00:00:00Z date_updated: 2025-07-21T07:28:03Z day: '06' department: - _id: UlWa - _id: HeEd doi: 10.1007/978-3-031-49275-4_2 external_id: arxiv: - '2202.12175' intvolume: ' 14466' language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.48550/arXiv.2202.12175 month: '01' oa: 1 oa_version: Preprint page: 18-33 project: - _id: bdb2a702-d553-11ed-ba76-f12e3e5a3bc6 grant_number: '101087907' name: 'A quantum hybrid of atoms and milligram-scale pendulums: towards gravitational quantum mechanics' publication: 31st International Symposium on Graph Drawing and Network Visualization publication_identifier: eissn: - 1611-3349 isbn: - '9783031492747' issn: - 0302-9743 publication_status: published publisher: Springer Nature quality_controlled: '1' scopus_import: '1' status: public title: Removing popular faces in curve arrangements type: conference user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 14466 year: '2024' ... --- _id: '14901' abstract: - lang: eng text: Global services like navigation, communication, and Earth observation have increased dramatically in the 21st century due to advances in outer space industries. But as orbits become increasingly crowded with both satellites and inevitable space debris pollution, continued operations become endangered by the heightened risks of debris collisions in orbit. Kessler Syndrome is the term for when a critical threshold of orbiting debris triggers a runaway positive feedback loop of debris collisions, creating debris congestion that can render orbits unusable. As this potential tipping point becomes more widely recognized, there have been renewed calls for debris mitigation and removal. Here, we combine complex systems and social-ecological systems approaches to study how these efforts may affect space debris accumulation and the likelihood of reaching Kessler Syndrome. Specifically, we model how debris levels are affected by future launch rates, cleanup activities, and collisions between extant debris. We contextualize and interpret our dynamic model within a discussion of existing space debris governance and other social, economic, and geopolitical factors that may influence effective collective management of the orbital commons. In line with previous studies, our model finds that debris congestion may be reached in less than 200 years, though a holistic management strategy combining removal and mitigation actions can avoid such outcomes while continuing space activities. Moreover, although active debris removal may be particularly effective, the current lack of market and governance support may impede its implementation. Research into these critical dynamics and the multi-faceted variables that influence debris outcomes can support policymakers in curating impactful governance strategies and realistic transition pathways to sustaining debris-free orbits. Overall, our study is useful for communicating about space debris sustainability in policy and education settings by providing an exploration of policy portfolio options supported by a simple and clear social-ecological modeling approach. acknowledgement: The authors would like to thank the special issue co-editors, Marco Janssen and Xiao-Shan Yap, and the anonymous reviewers for their comments that helped improve the manuscript. The paper also benefited from suggestions by other author participants in this special issue. We would also like to thank the 2022 Santa Fe Institute Complex Systems Summer School for providing space to initiate this study. article_processing_charge: Yes article_type: original author: - first_name: Keiko full_name: Nomura, Keiko last_name: Nomura - first_name: Simon full_name: Rella, Simon id: B4765ACA-AA38-11E9-AC9A-0930E6697425 last_name: Rella - first_name: Haily full_name: Merritt, Haily last_name: Merritt - first_name: Mathieu full_name: Baltussen, Mathieu last_name: Baltussen - first_name: Darcy full_name: Bird, Darcy last_name: Bird - first_name: Annika full_name: Tjuka, Annika last_name: Tjuka - first_name: Dan full_name: Falk, Dan last_name: Falk citation: ama: Nomura K, Rella S, Merritt H, et al. Tipping points of space debris in low earth orbit. International Journal of the Commons. 2024;18(1). doi:10.5334/ijc.1275 apa: Nomura, K., Rella, S., Merritt, H., Baltussen, M., Bird, D., Tjuka, A., & Falk, D. (2024). Tipping points of space debris in low earth orbit. International Journal of the Commons. Ubiquity Press. https://doi.org/10.5334/ijc.1275 chicago: Nomura, Keiko, Simon Rella, Haily Merritt, Mathieu Baltussen, Darcy Bird, Annika Tjuka, and Dan Falk. “Tipping Points of Space Debris in Low Earth Orbit.” International Journal of the Commons. Ubiquity Press, 2024. https://doi.org/10.5334/ijc.1275. ieee: K. Nomura et al., “Tipping points of space debris in low earth orbit,” International Journal of the Commons, vol. 18, no. 1. Ubiquity Press, 2024. ista: Nomura K, Rella S, Merritt H, Baltussen M, Bird D, Tjuka A, Falk D. 2024. Tipping points of space debris in low earth orbit. International Journal of the Commons. 18(1). mla: Nomura, Keiko, et al. “Tipping Points of Space Debris in Low Earth Orbit.” International Journal of the Commons, vol. 18, no. 1, Ubiquity Press, 2024, doi:10.5334/ijc.1275. short: K. Nomura, S. Rella, H. Merritt, M. Baltussen, D. Bird, A. Tjuka, D. Falk, International Journal of the Commons 18 (2024). date_created: 2024-01-30T11:58:02Z date_published: 2024-01-11T00:00:00Z date_updated: 2024-02-05T10:10:27Z day: '11' ddc: - '550' department: - _id: GradSch - _id: GaTk doi: 10.5334/ijc.1275 file: - access_level: open_access checksum: b80ebc889033c365d8f8c05a0c655382 content_type: application/pdf creator: dernst date_created: 2024-02-05T10:06:35Z date_updated: 2024-02-05T10:06:35Z file_id: '14939' file_name: 2023_IntJourCommons_Nomura.pdf file_size: 1305786 relation: main_file success: 1 file_date_updated: 2024-02-05T10:06:35Z has_accepted_license: '1' intvolume: ' 18' issue: '1' keyword: - Sociology and Political Science language: - iso: eng month: '01' oa: 1 oa_version: Published Version publication: International Journal of the Commons publication_identifier: issn: - 1875-0281 publication_status: published publisher: Ubiquity Press quality_controlled: '1' scopus_import: '1' status: public title: Tipping points of space debris in low earth orbit tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 18 year: '2024' ... --- _id: '14930' abstract: - lang: eng text: In this paper we investigate locally free representations of a quiver Q over a commutative Frobenius algebra R by arithmetic Fourier transform. When the base field is finite we prove that the number of isomorphism classes of absolutely indecomposable locally free representations of fixed rank is independent of the orientation of Q. We also prove that the number of isomorphism classes of locally free absolutely indecomposable representations of the preprojective algebra of Q over R equals the number of isomorphism classes of locally free absolutely indecomposable representations of Q over R[t]/(t2). Using these results together with results of Geiss, Leclerc and Schröer we give, when k is algebraically closed, a classification of pairs (Q, R) such that the set of isomorphism classes of indecomposable locally free representations of Q over R is finite. Finally when the representation is free of rank 1 at each vertex of Q, we study the function that counts the number of isomorphism classes of absolutely indecomposable locally free representations of Q over the Frobenius algebra Fq[t]/(tr). We prove that they are polynomial in q and their generating function is rational and satisfies a functional equation. acknowledgement: Special thanks go to Christof Geiss, Bernard Leclerc and Jan Schröer for explaining their work but also for sharing some unpublished results with us. We also thank the referee for many useful suggestions. We would like to thank Tommaso Scognamiglio for pointing out a mistake in the proof of Proposition 5.17 in an earlier version of the paper. We would like also to thank Alexander Beilinson, Bill Crawley-Boevey, Joel Kamnitzer, and Peng Shan for useful discussions. article_number: '20' article_processing_charge: No article_type: original author: - first_name: Tamás full_name: Hausel, Tamás id: 4A0666D8-F248-11E8-B48F-1D18A9856A87 last_name: Hausel - first_name: Emmanuel full_name: Letellier, Emmanuel last_name: Letellier - first_name: Fernando full_name: Rodriguez-Villegas, Fernando last_name: Rodriguez-Villegas citation: ama: Hausel T, Letellier E, Rodriguez-Villegas F. Locally free representations of quivers over commutative Frobenius algebras. Selecta Mathematica. 2024;30(2). doi:10.1007/s00029-023-00914-2 apa: Hausel, T., Letellier, E., & Rodriguez-Villegas, F. (2024). Locally free representations of quivers over commutative Frobenius algebras. Selecta Mathematica. Springer Nature. https://doi.org/10.1007/s00029-023-00914-2 chicago: Hausel, Tamás, Emmanuel Letellier, and Fernando Rodriguez-Villegas. “Locally Free Representations of Quivers over Commutative Frobenius Algebras.” Selecta Mathematica. Springer Nature, 2024. https://doi.org/10.1007/s00029-023-00914-2. ieee: T. Hausel, E. Letellier, and F. Rodriguez-Villegas, “Locally free representations of quivers over commutative Frobenius algebras,” Selecta Mathematica, vol. 30, no. 2. Springer Nature, 2024. ista: Hausel T, Letellier E, Rodriguez-Villegas F. 2024. Locally free representations of quivers over commutative Frobenius algebras. Selecta Mathematica. 30(2), 20. mla: Hausel, Tamás, et al. “Locally Free Representations of Quivers over Commutative Frobenius Algebras.” Selecta Mathematica, vol. 30, no. 2, 20, Springer Nature, 2024, doi:10.1007/s00029-023-00914-2. short: T. Hausel, E. Letellier, F. Rodriguez-Villegas, Selecta Mathematica 30 (2024). date_created: 2024-02-04T23:00:53Z date_published: 2024-01-27T00:00:00Z date_updated: 2024-02-05T12:58:21Z day: '27' department: - _id: TaHa doi: 10.1007/s00029-023-00914-2 intvolume: ' 30' issue: '2' language: - iso: eng month: '01' oa_version: None publication: Selecta Mathematica publication_identifier: eissn: - 1420-9020 issn: - 1022-1824 publication_status: epub_ahead publisher: Springer Nature quality_controlled: '1' scopus_import: '1' status: public title: Locally free representations of quivers over commutative Frobenius algebras type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 30 year: '2024' ... --- _id: '14931' abstract: - lang: eng text: We prove an upper bound on the ground state energy of the dilute spin-polarized Fermi gas capturing the leading correction to the kinetic energy resulting from repulsive interactions. One of the main ingredients in the proof is a rigorous implementation of the fermionic cluster expansion of Gaudin et al. (1971) [15]. acknowledgement: A.B.L. would like to thank Johannes Agerskov and Jan Philip Solovej for valuable discussions. We thank Alessandro Giuliani for helpful discussions and for pointing out the reference [18]. Funding from the European Union's Horizon 2020 research and innovation programme under the ERC grant agreement No 694227 is acknowledged. Financial support by the Austrian Science Fund (FWF) through project number I 6427-N (as part of the SFB/TRR 352) is gratefully acknowledged. article_number: '110320' article_processing_charge: Yes (in subscription journal) article_type: original arxiv: 1 author: - first_name: Asbjørn Bækgaard full_name: Lauritsen, Asbjørn Bækgaard id: e1a2682f-dc8d-11ea-abe3-81da9ac728f1 last_name: Lauritsen orcid: 0000-0003-4476-2288 - first_name: Robert full_name: Seiringer, Robert id: 4AFD0470-F248-11E8-B48F-1D18A9856A87 last_name: Seiringer orcid: 0000-0002-6781-0521 citation: ama: 'Lauritsen AB, Seiringer R. Ground state energy of the dilute spin-polarized Fermi gas: Upper bound via cluster expansion. Journal of Functional Analysis. 2024;286(7). doi:10.1016/j.jfa.2024.110320' apa: 'Lauritsen, A. B., & Seiringer, R. (2024). Ground state energy of the dilute spin-polarized Fermi gas: Upper bound via cluster expansion. Journal of Functional Analysis. Elsevier. https://doi.org/10.1016/j.jfa.2024.110320' chicago: 'Lauritsen, Asbjørn Bækgaard, and Robert Seiringer. “Ground State Energy of the Dilute Spin-Polarized Fermi Gas: Upper Bound via Cluster Expansion.” Journal of Functional Analysis. Elsevier, 2024. https://doi.org/10.1016/j.jfa.2024.110320.' ieee: 'A. B. Lauritsen and R. Seiringer, “Ground state energy of the dilute spin-polarized Fermi gas: Upper bound via cluster expansion,” Journal of Functional Analysis, vol. 286, no. 7. Elsevier, 2024.' ista: 'Lauritsen AB, Seiringer R. 2024. Ground state energy of the dilute spin-polarized Fermi gas: Upper bound via cluster expansion. Journal of Functional Analysis. 286(7), 110320.' mla: 'Lauritsen, Asbjørn Bækgaard, and Robert Seiringer. “Ground State Energy of the Dilute Spin-Polarized Fermi Gas: Upper Bound via Cluster Expansion.” Journal of Functional Analysis, vol. 286, no. 7, 110320, Elsevier, 2024, doi:10.1016/j.jfa.2024.110320.' short: A.B. Lauritsen, R. Seiringer, Journal of Functional Analysis 286 (2024). date_created: 2024-02-04T23:00:53Z date_published: 2024-01-24T00:00:00Z date_updated: 2024-02-05T12:53:21Z day: '24' department: - _id: RoSe doi: 10.1016/j.jfa.2024.110320 ec_funded: 1 external_id: arxiv: - '2301.04894' intvolume: ' 286' issue: '7' language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.1016/j.jfa.2024.110320 month: '01' oa: 1 oa_version: Published Version project: - _id: 25C6DC12-B435-11E9-9278-68D0E5697425 call_identifier: H2020 grant_number: '694227' name: Analysis of quantum many-body systems - _id: bda63fe5-d553-11ed-ba76-a16e3d2f256b grant_number: I06427 name: Mathematical Challenges in BCS Theory of Superconductivity publication: Journal of Functional Analysis publication_identifier: eissn: - 1096--0783 issn: - 0022-1236 publication_status: epub_ahead publisher: Elsevier quality_controlled: '1' scopus_import: '1' status: public title: 'Ground state energy of the dilute spin-polarized Fermi gas: Upper bound via cluster expansion' type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 286 year: '2024' ... --- _id: '14932' abstract: - lang: eng text: The huge antlers of the extinct Irish elk have invited evolutionary speculation since Darwin. In the 1970s, Stephen Jay Gould presented the first extensive data on antler size in the Irish elk and combined these with comparative data from other deer to test the hypothesis that the gigantic antlers were the outcome of a positive allometry that constrained large-bodied deer to have proportionally even larger antlers. He concluded that the Irish elk had antlers as predicted for its size and interpreted this within his emerging framework of developmental constraints as an explanatory factor in evolution. Here we reanalyze antler allometry based on new morphometric data for 57 taxa of the family Cervidae. We also present a new phylogeny for the Cervidae, which we use for comparative analyses. In contrast to Gould, we find that the antlers of Irish elk were larger than predicted from the allometry within the true deer, Cervini, as analyzed by Gould, but follow the allometry across Cervidae as a whole. After dissecting the discrepancy, we reject the allometric-constraint hypothesis because, contrary to Gould, we find no similarity between static and evolutionary allometries, and because we document extensive non-allometric evolution of antler size across the Cervidae. acknowledgement: "Open access funding provided by University of Oslo (incl Oslo University Hospital).\r\nWe thank Adrian Lister, Louis Tomsett, Roberto Portela Miguez and Roula Pappa (NHMUK), Brian O'Toole and Eileen Westwig (AMNH), Daniela Kalthoff (NHRM), Alexander Bibl and Zachos Frank (NHMW), Darrin Lunde and John Ososky (NMNH), Matthew Parkes and Nigel Monaghan (NMI), Elizabetta Cioppi and Luca Bellucci (IGF), and Yoshihiro Tanaka and Hiroyuki Taruno (OMNH), who helped us in obtaining the museum data, and a special thanks to Jørgen Sikkeland (NTNU NHM) for assistance in obtaining the ontogenetic data for the red deer. We thank Olja Toljagic and Kjetil L. Voje for discussions, Ayumu Tsuboi for assistance with data collection, and Jean-Michel Gaillard and the anonymous reviewers for comments on the manuscript. We thank the Centre of Advanced Study (CAS) at the Norwegian Academy of Sciences and Letters for hosting us during the academic year of 2019/2020 when much of the analysis and writing were done. MT was funded by JSPS Research Fellowship for Young Scientists (201603238)." article_processing_charge: Yes (via OA deal) article_type: original author: - first_name: Masahito full_name: Tsuboi, Masahito last_name: Tsuboi - first_name: Bjørn Tore full_name: Kopperud, Bjørn Tore last_name: Kopperud - first_name: Michael full_name: Matschiner, Michael last_name: Matschiner - first_name: Mark full_name: Grabowski, Mark last_name: Grabowski - first_name: Chrsitine full_name: Syrowatka, Chrsitine id: 205ffb76-7fe7-11eb-aa17-958bd11b99ad last_name: Syrowatka - first_name: Christophe full_name: Pélabon, Christophe last_name: Pélabon - first_name: Thomas F. full_name: Hansen, Thomas F. last_name: Hansen citation: ama: Tsuboi M, Kopperud BT, Matschiner M, et al. Antler allometry, the Irish elk and Gould revisited. Evolutionary Biology. 2024. doi:10.1007/s11692-023-09624-1 apa: Tsuboi, M., Kopperud, B. T., Matschiner, M., Grabowski, M., Syrowatka, C., Pélabon, C., & Hansen, T. F. (2024). Antler allometry, the Irish elk and Gould revisited. Evolutionary Biology. Springer Nature. https://doi.org/10.1007/s11692-023-09624-1 chicago: Tsuboi, Masahito, Bjørn Tore Kopperud, Michael Matschiner, Mark Grabowski, Chrsitine Syrowatka, Christophe Pélabon, and Thomas F. Hansen. “Antler Allometry, the Irish Elk and Gould Revisited.” Evolutionary Biology. Springer Nature, 2024. https://doi.org/10.1007/s11692-023-09624-1. ieee: M. Tsuboi et al., “Antler allometry, the Irish elk and Gould revisited,” Evolutionary Biology. Springer Nature, 2024. ista: Tsuboi M, Kopperud BT, Matschiner M, Grabowski M, Syrowatka C, Pélabon C, Hansen TF. 2024. Antler allometry, the Irish elk and Gould revisited. Evolutionary Biology. mla: Tsuboi, Masahito, et al. “Antler Allometry, the Irish Elk and Gould Revisited.” Evolutionary Biology, Springer Nature, 2024, doi:10.1007/s11692-023-09624-1. short: M. Tsuboi, B.T. Kopperud, M. Matschiner, M. Grabowski, C. Syrowatka, C. Pélabon, T.F. Hansen, Evolutionary Biology (2024). date_created: 2024-02-04T23:00:53Z date_published: 2024-01-29T00:00:00Z date_updated: 2024-02-05T12:43:58Z day: '29' department: - _id: MaRo doi: 10.1007/s11692-023-09624-1 language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.1007/s11692-023-09624-1 month: '01' oa: 1 oa_version: Published Version publication: Evolutionary Biology publication_identifier: eissn: - 1934-2845 issn: - 0071-3260 publication_status: epub_ahead publisher: Springer Nature quality_controlled: '1' scopus_import: '1' status: public title: Antler allometry, the Irish elk and Gould revisited type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 year: '2024' ... --- _id: '14933' abstract: - lang: eng text: Centrioles are part of centrosomes and cilia, which are microtubule organising centres (MTOC) with diverse functions. Despite their stability, centrioles can disappear during differentiation, such as in oocytes, but little is known about the regulation of their structural integrity. Our previous research revealed that the pericentriolar material (PCM) that surrounds centrioles and its recruiter, Polo kinase, are downregulated in oogenesis and sufficient for maintaining both centrosome structural integrity and MTOC activity. We now show that the expression of specific components of the centriole cartwheel and wall, including ANA1/CEP295, is essential for maintaining centrosome integrity. We find that Polo kinase requires ANA1 to promote centriole stability in cultured cells and eggs. In addition, ANA1 expression prevents the loss of centrioles observed upon PCM-downregulation. However, the centrioles maintained by overexpressing and tethering ANA1 are inactive, unlike the MTOCs observed upon tethering Polo kinase. These findings demonstrate that several centriole components are needed to maintain centrosome structure. Our study also highlights that centrioles are more dynamic than previously believed, with their structural stability relying on the continuous expression of multiple components. acknowledgement: We thank all members of the Cell Cycle and Regulation Lab for the discussions and for the critical reading of the manuscript. We thank Tomer Avidor-Reiss (University of Toledo, Toledo, OH), Daniel St. Johnston (The Gurdon Institute, Cambridge, UK), David Glover (University of Cambridge, Cambridge, UK), Jingyan Fu (Agricultural University, Beijing, China) Jordan Raff (University of Oxford, Oxford, UK) and Timothy Megraw (Florida State University, Tallahassee, FL) for sharing tools. We acknowledge the technical support of Instituto Gulbenkian de Ciência (IGC)‘s Advanced Imaging Facility, in particular Gabriel Martins, Nuno Pimpão Martins and José Marques. We also thank Tiago Paixão from the IGC’s Quantitative & Digital Science Unit and Marco Louro from the CCR lab for the support provided on statistical analysis. IGC’s Advanced Imaging Facility (AIF-UIC) is supported by the national Portuguese funding ref# PPBI-POCI-01-0145-FEDER -022122. We thank the IGC’s Fly Facility, supported by CONGENTO (LISBOA-01-0145-FEDER-022170). This work was supported by an ERC grant (ERC-2015-CoG-683258) awarded to MBD and a grant from the Portuguese Research Council (FCT) awarded to APM (PTDC/BIA-BID/32225/2017). article_processing_charge: Yes (in subscription journal) article_type: original author: - first_name: Ana full_name: Pimenta-Marques, Ana last_name: Pimenta-Marques - first_name: Tania full_name: Perestrelo, Tania last_name: Perestrelo - first_name: Patricia full_name: Dos Reis Rodrigues, Patricia id: 26E95904-5160-11E9-9C0B-C5B0DC97E90F last_name: Dos Reis Rodrigues orcid: 0000-0003-1681-508X - first_name: Paulo full_name: Duarte, Paulo last_name: Duarte - first_name: Ana full_name: Ferreira-Silva, Ana last_name: Ferreira-Silva - first_name: Mariana full_name: Lince-Faria, Mariana last_name: Lince-Faria - first_name: Mónica full_name: Bettencourt-Dias, Mónica last_name: Bettencourt-Dias citation: ama: Pimenta-Marques A, Perestrelo T, Dos Reis Rodrigues P, et al. Ana1/CEP295 is an essential player in the centrosome maintenance program regulated by Polo kinase and the PCM. EMBO reports. 2024;25(1):102-127. doi:10.1038/s44319-023-00020-6 apa: Pimenta-Marques, A., Perestrelo, T., Dos Reis Rodrigues, P., Duarte, P., Ferreira-Silva, A., Lince-Faria, M., & Bettencourt-Dias, M. (2024). Ana1/CEP295 is an essential player in the centrosome maintenance program regulated by Polo kinase and the PCM. EMBO Reports. Embo Press. https://doi.org/10.1038/s44319-023-00020-6 chicago: Pimenta-Marques, Ana, Tania Perestrelo, Patricia Dos Reis Rodrigues, Paulo Duarte, Ana Ferreira-Silva, Mariana Lince-Faria, and Mónica Bettencourt-Dias. “Ana1/CEP295 Is an Essential Player in the Centrosome Maintenance Program Regulated by Polo Kinase and the PCM.” EMBO Reports. Embo Press, 2024. https://doi.org/10.1038/s44319-023-00020-6. ieee: A. Pimenta-Marques et al., “Ana1/CEP295 is an essential player in the centrosome maintenance program regulated by Polo kinase and the PCM,” EMBO reports, vol. 25, no. 1. Embo Press, pp. 102–127, 2024. ista: Pimenta-Marques A, Perestrelo T, Dos Reis Rodrigues P, Duarte P, Ferreira-Silva A, Lince-Faria M, Bettencourt-Dias M. 2024. Ana1/CEP295 is an essential player in the centrosome maintenance program regulated by Polo kinase and the PCM. EMBO reports. 25(1), 102–127. mla: Pimenta-Marques, Ana, et al. “Ana1/CEP295 Is an Essential Player in the Centrosome Maintenance Program Regulated by Polo Kinase and the PCM.” EMBO Reports, vol. 25, no. 1, Embo Press, 2024, pp. 102–27, doi:10.1038/s44319-023-00020-6. short: A. Pimenta-Marques, T. Perestrelo, P. Dos Reis Rodrigues, P. Duarte, A. Ferreira-Silva, M. Lince-Faria, M. Bettencourt-Dias, EMBO Reports 25 (2024) 102–127. date_created: 2024-02-04T23:00:53Z date_published: 2024-01-10T00:00:00Z date_updated: 2024-02-05T12:37:07Z day: '10' ddc: - '570' department: - _id: MiSi doi: 10.1038/s44319-023-00020-6 file: - access_level: open_access checksum: 53c3ef43d9bd6d7bff3ffcf57d763cac content_type: application/pdf creator: dernst date_created: 2024-02-05T12:35:03Z date_updated: 2024-02-05T12:35:03Z file_id: '14941' file_name: 2023_EmboReports_PimentaMarques.pdf file_size: 9645056 relation: main_file success: 1 file_date_updated: 2024-02-05T12:35:03Z has_accepted_license: '1' intvolume: ' 25' issue: '1' language: - iso: eng month: '01' oa: 1 oa_version: Published Version page: 102-127 publication: EMBO reports publication_identifier: eissn: - 1469-3178 publication_status: published publisher: Embo Press quality_controlled: '1' scopus_import: '1' status: public title: Ana1/CEP295 is an essential player in the centrosome maintenance program regulated by Polo kinase and the PCM tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 25 year: '2024' ... --- _id: '14934' abstract: - lang: eng text: "We study random perturbations of a Riemannian manifold (M, g) by means of so-called\r\nFractional Gaussian Fields, which are defined intrinsically by the given manifold. The fields\r\nh• : ω \x02→ hω will act on the manifold via the conformal transformation g \x02→ gω := e2hω g.\r\nOur focus will be on the regular case with Hurst parameter H > 0, the critical case H = 0\r\nbeing the celebrated Liouville geometry in two dimensions. We want to understand how basic\r\ngeometric and functional-analytic quantities like diameter, volume, heat kernel, Brownian\r\nmotion, spectral bound, or spectral gap change under the influence of the noise. And if so, is\r\nit possible to quantify these dependencies in terms of key parameters of the noise? Another\r\ngoal is to define and analyze in detail the Fractional Gaussian Fields on a general Riemannian\r\nmanifold, a fascinating object of independent interest." acknowledgement: "The authors would like to thank Matthias Erbar and Ronan Herry for valuable discussions on this project. They are also grateful to Nathanaël Berestycki, and Fabrice Baudoin for respectively pointing out the references [7], and [6, 24], and to Julien Fageot and Thomas Letendre for pointing out a mistake in a previous version of the proof of Proposition 3.10. The authors feel very much indebted to an anonymous reviewer for his/her careful reading and the many valuable suggestions that have significantly contributed to the improvement of the paper. L.D.S. gratefully acknowledges financial support by the Deutsche Forschungsgemeinschaft through CRC 1060 as well as through SPP 2265, and by the Austrian Science Fund (FWF) grant F65 at Institute of Science and Technology Austria. This research was funded in whole or in part by the Austrian Science Fund (FWF) ESPRIT 208. For the purpose of open access, the authors have applied a CC BY public copyright licence to any Author Accepted Manuscript version arising from this submission. E.K. and K.-T.S. gratefully acknowledge funding by the Deutsche Forschungsgemeinschaft through the Hausdorff Center for Mathematics and through CRC 1060 as well as through SPP 2265.\r\nOpen Access funding enabled and organized by Projekt DEAL." article_processing_charge: Yes (via OA deal) article_type: original author: - first_name: Lorenzo full_name: Dello Schiavo, Lorenzo id: ECEBF480-9E4F-11EA-B557-B0823DDC885E last_name: Dello Schiavo orcid: 0000-0002-9881-6870 - first_name: Eva full_name: Kopfer, Eva last_name: Kopfer - first_name: Karl Theodor full_name: Sturm, Karl Theodor last_name: Sturm citation: ama: Dello Schiavo L, Kopfer E, Sturm KT. A discovery tour in random Riemannian geometry. Potential Analysis. 2024. doi:10.1007/s11118-023-10118-0 apa: Dello Schiavo, L., Kopfer, E., & Sturm, K. T. (2024). A discovery tour in random Riemannian geometry. Potential Analysis. Springer Nature. https://doi.org/10.1007/s11118-023-10118-0 chicago: Dello Schiavo, Lorenzo, Eva Kopfer, and Karl Theodor Sturm. “A Discovery Tour in Random Riemannian Geometry.” Potential Analysis. Springer Nature, 2024. https://doi.org/10.1007/s11118-023-10118-0. ieee: L. Dello Schiavo, E. Kopfer, and K. T. Sturm, “A discovery tour in random Riemannian geometry,” Potential Analysis. Springer Nature, 2024. ista: Dello Schiavo L, Kopfer E, Sturm KT. 2024. A discovery tour in random Riemannian geometry. Potential Analysis. mla: Dello Schiavo, Lorenzo, et al. “A Discovery Tour in Random Riemannian Geometry.” Potential Analysis, Springer Nature, 2024, doi:10.1007/s11118-023-10118-0. short: L. Dello Schiavo, E. Kopfer, K.T. Sturm, Potential Analysis (2024). date_created: 2024-02-04T23:00:54Z date_published: 2024-01-26T00:00:00Z date_updated: 2024-02-05T13:04:23Z day: '26' department: - _id: JaMa doi: 10.1007/s11118-023-10118-0 language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.1007/s11118-023-10118-0 month: '01' oa: 1 oa_version: Published Version project: - _id: fc31cba2-9c52-11eb-aca3-ff467d239cd2 grant_number: F6504 name: Taming Complexity in Partial Differential Systems publication: Potential Analysis publication_identifier: eissn: - 1572-929X issn: - 0926-2601 publication_status: epub_ahead publisher: Springer Nature quality_controlled: '1' scopus_import: '1' status: public title: A discovery tour in random Riemannian geometry type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 year: '2024' ... --- _id: '14938' abstract: - lang: eng text: High elevation headwater catchments are complex hydrological systems that seasonally buffer water and release it in the form of snow and ice melt, modulating downstream runoff regimes and water availability. In High Mountain Asia (HMA), where a wide range of climates from semi-arid to monsoonal exist, the importance of the cryospheric contributions to the water budget varies with the amount and seasonal distribution of precipitation. Losses due to evapotranspiration and sublimation are to date largely unquantified components of the water budget in such catchments, although they can be comparable in magnitude to glacier melt contributions to streamflow. 
Here, we simulate the hydrology of three high elevation headwater catchments in distinct climates in HMA over 10 years using an ecohydrological model geared towards high-mountain areas including snow and glaciers, forced with reanalysis data. 
Our results show that evapotranspiration and sublimation together are most important at the semi-arid site, Kyzylsu, on the northernmost slopes of the Pamir mountain range. Here, the evaporative loss amounts to 28% of the water throughput, which we define as the total water added to, or removed from the water balance within a year. In comparison, evaporative losses are 19% at the Central Himalayan site Langtang and 13% at the wettest site, 24K, on the Southeastern Tibetan Plateau. At the three sites, respectively, sublimation removes 15%, 13% and 6% of snowfall, while evapotranspiration removes the equivalent of 76%, 28% and 19% of rainfall. In absolute terms, and across a comparable elevation range, the highest ET flux is 413 mm yr-1 at 24K, while the highest sublimation flux is 91 mm yr-1 at Kyzylsu. During warm and dry years, glacier melt was found to only partially compensate for the annual supply deficit. article_processing_charge: Yes article_type: original author: - first_name: Stefan full_name: Fugger, Stefan id: 86698d64-c4c6-11ee-af02-cdf1e6a7d31f last_name: Fugger - first_name: Thomas full_name: Shaw, Thomas id: 3caa3f91-1f03-11ee-96ce-e0e553054d6e last_name: Shaw orcid: 0000-0001-7640-6152 - first_name: Achille full_name: Jouberton, Achille last_name: Jouberton - first_name: Evan full_name: Miles, Evan last_name: Miles - first_name: Pascal full_name: Buri, Pascal id: 317987aa-9421-11ee-ac5a-b941b041abba last_name: Buri - first_name: Michael full_name: McCarthy, Michael id: 22a2674a-61ce-11ee-94b5-d18813baf16f last_name: McCarthy - first_name: Catriona Louise full_name: Fyffe, Catriona Louise id: 001b0422-8d15-11ed-bc51-cab6c037a228 last_name: Fyffe - first_name: Simone full_name: Fatichi, Simone last_name: Fatichi - first_name: Marin full_name: Kneib, Marin last_name: Kneib - first_name: Peter full_name: Molnar, Peter last_name: Molnar - first_name: Francesca full_name: Pellicciotti, Francesca id: b28f055a-81ea-11ed-b70c-a9fe7f7b0e70 last_name: Pellicciotti orcid: 0000-0002-5554-8087 citation: ama: Fugger S, Shaw T, Jouberton A, et al. Hydrological regimes and evaporative flux partitioning at the climatic ends of High Mountain Asia. Environmental Research Letters. doi:10.1088/1748-9326/ad25a0 apa: Fugger, S., Shaw, T., Jouberton, A., Miles, E., Buri, P., McCarthy, M., … Pellicciotti, F. (n.d.). Hydrological regimes and evaporative flux partitioning at the climatic ends of High Mountain Asia. Environmental Research Letters. IOP Publishing. https://doi.org/10.1088/1748-9326/ad25a0 chicago: Fugger, Stefan, Thomas Shaw, Achille Jouberton, Evan Miles, Pascal Buri, Michael McCarthy, Catriona Louise Fyffe, et al. “Hydrological Regimes and Evaporative Flux Partitioning at the Climatic Ends of High Mountain Asia.” Environmental Research Letters. IOP Publishing, n.d. https://doi.org/10.1088/1748-9326/ad25a0. ieee: S. Fugger et al., “Hydrological regimes and evaporative flux partitioning at the climatic ends of High Mountain Asia,” Environmental Research Letters. IOP Publishing. ista: Fugger S, Shaw T, Jouberton A, Miles E, Buri P, McCarthy M, Fyffe CL, Fatichi S, Kneib M, Molnar P, Pellicciotti F. Hydrological regimes and evaporative flux partitioning at the climatic ends of High Mountain Asia. Environmental Research Letters. mla: Fugger, Stefan, et al. “Hydrological Regimes and Evaporative Flux Partitioning at the Climatic Ends of High Mountain Asia.” Environmental Research Letters, IOP Publishing, doi:10.1088/1748-9326/ad25a0. short: S. Fugger, T. Shaw, A. Jouberton, E. Miles, P. Buri, M. McCarthy, C.L. Fyffe, S. Fatichi, M. Kneib, P. Molnar, F. Pellicciotti, Environmental Research Letters (n.d.). date_created: 2024-02-05T09:01:11Z date_published: 2024-02-02T00:00:00Z date_updated: 2024-02-06T08:35:39Z day: '02' ddc: - '550' department: - _id: FrPe doi: 10.1088/1748-9326/ad25a0 has_accepted_license: '1' keyword: - Public Health - Environmental and Occupational Health - General Environmental Science - Renewable Energy - Sustainability and the Environment language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.1088/1748-9326/ad25a0 month: '02' oa: 1 oa_version: Published Version publication: Environmental Research Letters publication_identifier: issn: - 1748-9326 publication_status: accepted publisher: IOP Publishing quality_controlled: '1' status: public title: Hydrological regimes and evaporative flux partitioning at the climatic ends of High Mountain Asia tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 year: '2024' ... --- _id: '14979' abstract: - lang: eng text: Poxviruses are among the largest double-stranded DNA viruses, with members such as variola virus, monkeypox virus and the vaccination strain vaccinia virus (VACV). Knowledge about the structural proteins that form the viral core has remained sparse. While major core proteins have been annotated via indirect experimental evidence, their structures have remained elusive and they could not be assigned to individual core features. Hence, which proteins constitute which layers of the core, such as the palisade layer and the inner core wall, has remained enigmatic. Here we show, using a multi-modal cryo-electron microscopy (cryo-EM) approach in combination with AlphaFold molecular modeling, that trimers formed by the cleavage product of VACV protein A10 are the key component of the palisade layer. This allows us to place previously obtained descriptions of protein interactions within the core wall into perspective and to provide a detailed model of poxvirus core architecture. Importantly, we show that interactions within A10 trimers are likely generalizable over members of orthopox- and parapoxviruses. acknowledged_ssus: - _id: ScienComp - _id: LifeSc - _id: EM-Fac acknowledgement: "We thank A. Bergthaler (Research Center for Molecular Medicine of the Austrian Academy of Sciences) for providing VACV WR. We thank A. Nicholas and his team at the ISTA proteomics facility, and S. Elefante at the ISTA Scientific Computing facility for their support. We also thank F. Fäßler, D. Porley, T. Muthspiel and other members of the Schur group for support and helpful discussions. We also thank D. Castaño-Díez for support with Dynamo. We thank D. Farrell for his help optimizing the Rosetta protocol to refine the atomic model into the cryo-EM map with symmetry.\r\n\r\nF.K.M.S. acknowledges support from ISTA and EMBO. F.K.M.S. also received support from the Austrian Science Fund (FWF) grant P31445. This publication has been made possible in part by CZI grant DAF2021-234754 and grant https://doi.org/10.37921/812628ebpcwg from the Chan Zuckerberg Initiative DAF, an advised fund of Silicon Valley Community Foundation (funder https://doi.org/10.13039/100014989) awarded to F.K.M.S.\r\n\r\nThis research was also supported by the Scientific Service Units (SSUs) of ISTA through resources provided by Scientific Computing (SciComp), the Life Science Facility (LSF), and the Electron Microscopy Facility (EMF). We also acknowledge the use of COSMIC45 and Colabfold46." article_processing_charge: Yes (in subscription journal) article_type: original author: - first_name: Julia full_name: Datler, Julia id: 3B12E2E6-F248-11E8-B48F-1D18A9856A87 last_name: Datler orcid: 0000-0002-3616-8580 - first_name: Jesse full_name: Hansen, Jesse id: 1063c618-6f9b-11ec-9123-f912fccded63 last_name: Hansen - first_name: Andreas full_name: Thader, Andreas id: 3A18A7B8-F248-11E8-B48F-1D18A9856A87 last_name: Thader - first_name: Alois full_name: Schlögl, Alois id: 45BF87EE-F248-11E8-B48F-1D18A9856A87 last_name: Schlögl orcid: 0000-0002-5621-8100 - first_name: Lukas W full_name: Bauer, Lukas W id: 0c894dcf-897b-11ed-a09c-8186353224b0 last_name: Bauer - first_name: Victor-Valentin full_name: Hodirnau, Victor-Valentin id: 3661B498-F248-11E8-B48F-1D18A9856A87 last_name: Hodirnau - first_name: Florian KM full_name: Schur, Florian KM id: 48AD8942-F248-11E8-B48F-1D18A9856A87 last_name: Schur orcid: 0000-0003-4790-8078 citation: ama: Datler J, Hansen J, Thader A, et al. Multi-modal cryo-EM reveals trimers of protein A10 to form the palisade layer in poxvirus cores. Nature Structural & Molecular Biology. 2024. doi:10.1038/s41594-023-01201-6 apa: Datler, J., Hansen, J., Thader, A., Schlögl, A., Bauer, L. W., Hodirnau, V.-V., & Schur, F. K. (2024). Multi-modal cryo-EM reveals trimers of protein A10 to form the palisade layer in poxvirus cores. Nature Structural & Molecular Biology. Springer Nature. https://doi.org/10.1038/s41594-023-01201-6 chicago: Datler, Julia, Jesse Hansen, Andreas Thader, Alois Schlögl, Lukas W Bauer, Victor-Valentin Hodirnau, and Florian KM Schur. “Multi-Modal Cryo-EM Reveals Trimers of Protein A10 to Form the Palisade Layer in Poxvirus Cores.” Nature Structural & Molecular Biology. Springer Nature, 2024. https://doi.org/10.1038/s41594-023-01201-6. ieee: J. Datler et al., “Multi-modal cryo-EM reveals trimers of protein A10 to form the palisade layer in poxvirus cores,” Nature Structural & Molecular Biology. Springer Nature, 2024. ista: Datler J, Hansen J, Thader A, Schlögl A, Bauer LW, Hodirnau V-V, Schur FK. 2024. Multi-modal cryo-EM reveals trimers of protein A10 to form the palisade layer in poxvirus cores. Nature Structural & Molecular Biology. mla: Datler, Julia, et al. “Multi-Modal Cryo-EM Reveals Trimers of Protein A10 to Form the Palisade Layer in Poxvirus Cores.” Nature Structural & Molecular Biology, Springer Nature, 2024, doi:10.1038/s41594-023-01201-6. short: J. Datler, J. Hansen, A. Thader, A. Schlögl, L.W. Bauer, V.-V. Hodirnau, F.K. Schur, Nature Structural & Molecular Biology (2024). date_created: 2024-02-12T09:59:45Z date_published: 2024-02-05T00:00:00Z date_updated: 2024-03-05T09:27:47Z day: '05' ddc: - '570' department: - _id: FlSc - _id: ScienComp - _id: EM-Fac doi: 10.1038/s41594-023-01201-6 external_id: pmid: - '38316877' has_accepted_license: '1' keyword: - Molecular Biology - Structural Biology language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.1038/s41594-023-01201-6 month: '02' oa: 1 oa_version: Published Version pmid: 1 project: - _id: 26736D6A-B435-11E9-9278-68D0E5697425 call_identifier: FWF grant_number: P31445 name: Structural conservation and diversity in retroviral capsid publication: Nature Structural & Molecular Biology publication_identifier: eissn: - 1545-9985 issn: - 1545-9993 publication_status: epub_ahead publisher: Springer Nature quality_controlled: '1' related_material: link: - description: News on ISTA Website relation: press_release url: https://ista.ac.at/en/news/down-to-the-core-of-poxviruses/ status: public title: Multi-modal cryo-EM reveals trimers of protein A10 to form the palisade layer in poxvirus cores tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 year: '2024' ... --- _id: '14980' abstract: - lang: eng text: Precision sensing and manipulation of milligram-scale mechanical oscillators has attracted growing interest in the fields of table-top explorations of gravity and tests of quantum mechanics at macroscopic scales. Torsional oscillators present an opportunity in this regard due to their remarked isolation from environmental noise. For torsional motion, an effective employment of optical cavities to enhance optomechanical interactions—as already established for linear oscillators—so far faced certain challenges. Here, we propose a concept for sensing and manipulating torsional motion, where exclusively the torsional rotations of a pendulum are mapped onto the path length of a single two-mirror optical cavity. The concept inherently alleviates many limitations of previous approaches. A proof-of-principle experiment is conducted with a rigidly controlled pendulum to explore the sensing aspects of the concept and to identify practical limitations in a potential state-of-the art setup. Based on this study, we anticipate development of precision torque sensors utilizing torsional pendulums that can support sensitivities below 10−19Nm/√Hz, while the motion of the pendulums are dominated by quantum radiation pressure noise at sub-microwatts of incoming laser power. These developments will provide horizons for experiments at the interface of quantum mechanics and gravity. acknowledgement: "We thank Pere Rosselló for his contributions to the initial modeling of the presented sensing technique. This work was supported by Institute of Science and Technology Austria, and\r\nthe European Research Council under Grant No. 101087907 (ERC CoG QuHAMP)." article_number: '013141' article_processing_charge: Yes article_type: original arxiv: 1 author: - first_name: Sofya full_name: Agafonova, Sofya id: 09501ff6-dca7-11ea-a8ae-b3e0b9166e80 last_name: Agafonova orcid: 0000-0003-0582-2946 - first_name: Umang full_name: Mishra, Umang id: 4328fa4c-f128-11eb-9611-c107b0fe4d51 last_name: Mishra - first_name: Fritz R full_name: Diorico, Fritz R id: 2E054C4C-F248-11E8-B48F-1D18A9856A87 last_name: Diorico orcid: 0000-0002-4947-8924 - first_name: Onur full_name: Hosten, Onur id: 4C02D85E-F248-11E8-B48F-1D18A9856A87 last_name: Hosten orcid: 0000-0002-2031-204X citation: ama: Agafonova S, Mishra U, Diorico FR, Hosten O. Zigzag optical cavity for sensing and controlling torsional motion. Physical Review Research. 2024;6(1). doi:10.1103/physrevresearch.6.013141 apa: Agafonova, S., Mishra, U., Diorico, F. R., & Hosten, O. (2024). Zigzag optical cavity for sensing and controlling torsional motion. Physical Review Research. American Physical Society. https://doi.org/10.1103/physrevresearch.6.013141 chicago: Agafonova, Sofya, Umang Mishra, Fritz R Diorico, and Onur Hosten. “Zigzag Optical Cavity for Sensing and Controlling Torsional Motion.” Physical Review Research. American Physical Society, 2024. https://doi.org/10.1103/physrevresearch.6.013141. ieee: S. Agafonova, U. Mishra, F. R. Diorico, and O. Hosten, “Zigzag optical cavity for sensing and controlling torsional motion,” Physical Review Research, vol. 6, no. 1. American Physical Society, 2024. ista: Agafonova S, Mishra U, Diorico FR, Hosten O. 2024. Zigzag optical cavity for sensing and controlling torsional motion. Physical Review Research. 6(1), 013141. mla: Agafonova, Sofya, et al. “Zigzag Optical Cavity for Sensing and Controlling Torsional Motion.” Physical Review Research, vol. 6, no. 1, 013141, American Physical Society, 2024, doi:10.1103/physrevresearch.6.013141. short: S. Agafonova, U. Mishra, F.R. Diorico, O. Hosten, Physical Review Research 6 (2024). date_created: 2024-02-12T11:42:18Z date_published: 2024-02-05T00:00:00Z date_updated: 2024-02-12T11:49:06Z day: '05' ddc: - '530' department: - _id: OnHo doi: 10.1103/physrevresearch.6.013141 external_id: arxiv: - '2306.12804' file: - access_level: open_access checksum: 3a39ebffb24c1cc1dd0b547a726dc52d content_type: application/pdf creator: dernst date_created: 2024-02-12T11:46:50Z date_updated: 2024-02-12T11:46:50Z file_id: '14981' file_name: 2024_PhysicalRevResearch_Agafonova.pdf file_size: 1437167 relation: main_file success: 1 file_date_updated: 2024-02-12T11:46:50Z has_accepted_license: '1' intvolume: ' 6' issue: '1' language: - iso: eng month: '02' oa: 1 oa_version: Published Version project: - _id: bdb2a702-d553-11ed-ba76-f12e3e5a3bc6 grant_number: '101087907' name: 'A quantum hybrid of atoms and milligram-scale pendulums: towards gravitational quantum mechanics' publication: Physical Review Research publication_identifier: eissn: - 2643-1564 publication_status: published publisher: American Physical Society quality_controlled: '1' status: public title: Zigzag optical cavity for sensing and controlling torsional motion tmp: image: /images/cc_by.png legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) short: CC BY (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 6 year: '2024' ... --- _id: '14986' abstract: - lang: eng text: We prove a version of the tamely ramified geometric Langlands correspondence in positive characteristic for GLn(k). Let k be an algebraically closed field of characteristic p>n. Let X be a smooth projective curve over k with marked points, and fix a parabolic subgroup of GLn(k) at each marked point. We denote by Bunn,P the moduli stack of (quasi-)parabolic vector bundles on X, and by Locn,P the moduli stack of parabolic flat connections such that the residue is nilpotent with respect to the parabolic reduction at each marked point. We construct an equivalence between the bounded derived category Db(Qcoh(Loc0n,P)) of quasi-coherent sheaves on an open substack Loc0n,P⊂Locn,P, and the bounded derived category Db(D0Bunn,P-mod) of D0Bunn,P-modules, where D0Bunn,P is a localization of DBunn,P the sheaf of crystalline differential operators on Bunn,P. Thus we extend the work of Bezrukavnikov-Braverman to the tamely ramified case. We also prove a correspondence between flat connections on X with regular singularities and meromorphic Higgs bundles on the Frobenius twist X(1) of X with first order poles . acknowledgement: "This work was supported by the NSF [DMS-1502125to S.S.]; and the European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie grant agreement [101034413 to S.S.].\r\nI would like to thank my advisor Tom Nevins for many helpful discussions on this subject and for his comments on this paper. I would like to thank Christopher Dodd, Michael Groechenig, and Tamas Hausel for helpful conversations. I would like to thank Tsao-Hsien Chen for useful comments on an earlier version of this paper." article_processing_charge: Yes (via OA deal) article_type: original arxiv: 1 author: - first_name: Shiyu full_name: Shen, Shiyu id: 544cccd3-9005-11ec-87bc-94aef1c5b814 last_name: Shen citation: ama: Shen S. Tamely ramified geometric Langlands correspondence in positive characteristic. International Mathematics Research Notices. 2024. doi:10.1093/imrn/rnae005 apa: Shen, S. (2024). Tamely ramified geometric Langlands correspondence in positive characteristic. International Mathematics Research Notices. Oxford University Press. https://doi.org/10.1093/imrn/rnae005 chicago: Shen, Shiyu. “Tamely Ramified Geometric Langlands Correspondence in Positive Characteristic.” International Mathematics Research Notices. Oxford University Press, 2024. https://doi.org/10.1093/imrn/rnae005. ieee: S. Shen, “Tamely ramified geometric Langlands correspondence in positive characteristic,” International Mathematics Research Notices. Oxford University Press, 2024. ista: Shen S. 2024. Tamely ramified geometric Langlands correspondence in positive characteristic. International Mathematics Research Notices. mla: Shen, Shiyu. “Tamely Ramified Geometric Langlands Correspondence in Positive Characteristic.” International Mathematics Research Notices, Oxford University Press, 2024, doi:10.1093/imrn/rnae005. short: S. Shen, International Mathematics Research Notices (2024). date_created: 2024-02-14T12:16:17Z date_published: 2024-02-05T00:00:00Z date_updated: 2024-02-19T10:22:44Z day: '05' department: - _id: TaHa doi: 10.1093/imrn/rnae005 ec_funded: 1 external_id: arxiv: - '1810.12491' keyword: - General Mathematics language: - iso: eng main_file_link: - open_access: '1' url: https://doi.org/10.1093/imrn/rnae005 month: '02' oa: 1 oa_version: Published Version project: - _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c call_identifier: H2020 grant_number: '101034413' name: 'IST-BRIDGE: International postdoctoral program' publication: International Mathematics Research Notices publication_identifier: eissn: - 1687-0247 issn: - 1073-7928 publication_status: epub_ahead publisher: Oxford University Press quality_controlled: '1' status: public title: Tamely ramified geometric Langlands correspondence in positive characteristic type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 year: '2024' ... --- _id: '15001' abstract: - lang: eng text: "Self-replication of amyloid fibrils via secondary nucleation is an intriguing physicochemical phenomenon in which existing fibrils catalyze the formation of their own copies. The molecular events behind this fibril surface-mediated process remain largely inaccessible to current structural and imaging techniques. Using statistical mechanics, computer modeling, and chemical kinetics, we show that the catalytic structure of the fibril surface can be inferred from the aggregation behavior in the presence and absence of a fibril-binding inhibitor. We apply our approach to the case of Alzheimer’s A\r\n amyloid fibrils formed in the presence of proSP-C Brichos inhibitors. We find that self-replication of A\r\n fibrils occurs on small catalytic sites on the fibril surface, which are far apart from each other, and each of which can be covered by a single Brichos inhibitor." acknowledgement: We acknowledge support from the Erasmus programme and the University College London Institute for the Physics of Living Systems (S.C., T.C.T.M., A.Š.), the Biotechnology and Biological Sciences Research Council (T.P.J.K.), the Engineering and Physical Sciences Research Council (D.F.), the European Research Council (T.P.J.K., S.L., D.F., and A.Š.), the Frances and Augustus Newman Foundation (T.P.J.K.), the Academy of Medical Sciences and Wellcome Trust (A.Š.), and the Royal Society (S.C. and A.Š.). article_number: e2220075121 article_processing_charge: Yes article_type: original author: - first_name: Samo full_name: Curk, Samo id: 031eff0d-d481-11ee-8508-cd12a7a86e5b last_name: Curk orcid: 0000-0001-6160-9766 - first_name: Johannes full_name: Krausser, Johannes last_name: Krausser - first_name: Georg full_name: Meisl, Georg last_name: Meisl - first_name: Daan full_name: Frenkel, Daan last_name: Frenkel - first_name: Sara full_name: Linse, Sara last_name: Linse - first_name: Thomas C.T. full_name: Michaels, Thomas C.T. last_name: Michaels - first_name: Tuomas P.J. full_name: Knowles, Tuomas P.J. last_name: Knowles - first_name: Anđela full_name: Šarić, Anđela id: bf63d406-f056-11eb-b41d-f263a6566d8b last_name: Šarić orcid: 0000-0002-7854-2139 citation: ama: Curk S, Krausser J, Meisl G, et al. Self-replication of Aβ42 aggregates occurs on small and isolated fibril sites. Proceedings of the National Academy of Sciences of the United States of America. 2024;121(7). doi:10.1073/pnas.2220075121 apa: Curk, S., Krausser, J., Meisl, G., Frenkel, D., Linse, S., Michaels, T. C. T., … Šarić, A. (2024). Self-replication of Aβ42 aggregates occurs on small and isolated fibril sites. Proceedings of the National Academy of Sciences of the United States of America. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.2220075121 chicago: Curk, Samo, Johannes Krausser, Georg Meisl, Daan Frenkel, Sara Linse, Thomas C.T. Michaels, Tuomas P.J. Knowles, and Anđela Šarić. “Self-Replication of Aβ42 Aggregates Occurs on Small and Isolated Fibril Sites.” Proceedings of the National Academy of Sciences of the United States of America. Proceedings of the National Academy of Sciences, 2024. https://doi.org/10.1073/pnas.2220075121. ieee: S. Curk et al., “Self-replication of Aβ42 aggregates occurs on small and isolated fibril sites,” Proceedings of the National Academy of Sciences of the United States of America, vol. 121, no. 7. Proceedings of the National Academy of Sciences, 2024. ista: Curk S, Krausser J, Meisl G, Frenkel D, Linse S, Michaels TCT, Knowles TPJ, Šarić A. 2024. Self-replication of Aβ42 aggregates occurs on small and isolated fibril sites. Proceedings of the National Academy of Sciences of the United States of America. 121(7), e2220075121. mla: Curk, Samo, et al. “Self-Replication of Aβ42 Aggregates Occurs on Small and Isolated Fibril Sites.” Proceedings of the National Academy of Sciences of the United States of America, vol. 121, no. 7, e2220075121, Proceedings of the National Academy of Sciences, 2024, doi:10.1073/pnas.2220075121. short: S. Curk, J. Krausser, G. Meisl, D. Frenkel, S. Linse, T.C.T. Michaels, T.P.J. Knowles, A. Šarić, Proceedings of the National Academy of Sciences of the United States of America 121 (2024). date_created: 2024-02-18T23:01:00Z date_published: 2024-02-13T00:00:00Z date_updated: 2024-02-26T08:45:56Z day: '13' ddc: - '570' department: - _id: AnSa doi: 10.1073/pnas.2220075121 ec_funded: 1 external_id: pmid: - '38335256' file: - access_level: open_access checksum: 5aeb65bcc0dd829b1f9ab307c5031d4b content_type: application/pdf creator: dernst date_created: 2024-02-26T08:20:00Z date_updated: 2024-02-26T08:20:00Z file_id: '15026' file_name: 2024_PNAS_Curk.pdf file_size: 7699487 relation: main_file success: 1 file_date_updated: 2024-02-26T08:20:00Z has_accepted_license: '1' intvolume: ' 121' issue: '7' language: - iso: eng license: https://creativecommons.org/licenses/by-nc-nd/4.0/ month: '02' oa: 1 oa_version: Published Version pmid: 1 project: - _id: eba2549b-77a9-11ec-83b8-a81e493eae4e call_identifier: H2020 grant_number: '802960' name: 'Non-Equilibrium Protein Assembly: from Building Blocks to Biological Machines' publication: Proceedings of the National Academy of Sciences of the United States of America publication_identifier: eissn: - 1091-6490 publication_status: published publisher: Proceedings of the National Academy of Sciences quality_controlled: '1' related_material: record: - id: '15027' relation: research_data status: public scopus_import: '1' status: public title: Self-replication of Aβ42 aggregates occurs on small and isolated fibril sites tmp: image: /images/cc_by_nc_nd.png legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) short: CC BY-NC-ND (4.0) type: journal_article user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87 volume: 121 year: '2024' ...