---
_id: '8261'
abstract:
- lang: eng
  text: Dentate gyrus granule cells (GCs) connect the entorhinal cortex to the hippocampal
    CA3 region, but how they process spatial information remains enigmatic. To examine
    the role of GCs in spatial coding, we measured excitatory postsynaptic potentials
    (EPSPs) and action potentials (APs) in head-fixed mice running on a linear belt.
    Intracellular recording from morphologically identified GCs revealed that most
    cells were active, but activity level varied over a wide range. Whereas only ∼5%
    of GCs showed spatially tuned spiking, ∼50% received spatially tuned input. Thus,
    the GC population broadly encodes spatial information, but only a subset relays
    this information to the CA3 network. Fourier analysis indicated that GCs received
    conjunctive place-grid-like synaptic input, suggesting code conversion in single
    neurons. GC firing was correlated with dendritic complexity and intrinsic excitability,
    but not extrinsic excitatory input or dendritic cable properties. Thus, functional
    maturation may control input-output transformation and spatial code conversion.
acknowledged_ssus:
- _id: M-Shop
- _id: ScienComp
- _id: PreCl
acknowledgement: This project has received funding from the European Research Council
  (ERC) under the European Union’s Horizon 2020 research and innovation program (grant
  agreement 692692, P.J.) and the Fond zur Förderung der Wissenschaftlichen Forschung
  (Z 312-B27, Wittgenstein award, P.J.). We thank Gyorgy Buzsáki, Jozsef Csicsvari,
  Juan Ramirez Villegas, and Federico Stella for commenting on earlier versions of
  this manuscript. We also thank Katie Bittner, Michael Brecht, Albert Lee, Jeffery
  Magee, and Alejandro Pernía-Andrade for sharing expertise in in vivo patch-clamp
  recording. We are grateful to Florian Marr for cell labeling, cell reconstruction,
  and technical assistance; Ben Suter for helpful discussions; Christina Altmutter
  for technical support; Eleftheria Kralli-Beller for manuscript editing; and Todor
  Asenov (Machine Shop) for device construction. We also thank the Scientific Service
  Units (SSUs) of IST Austria (Machine Shop, Scientific Computing, and Preclinical
  Facility) for efficient support.
article_processing_charge: No
article_type: original
author:
- first_name: Xiaomin
  full_name: Zhang, Xiaomin
  id: 423EC9C2-F248-11E8-B48F-1D18A9856A87
  last_name: Zhang
- first_name: Alois
  full_name: Schlögl, Alois
  id: 45BF87EE-F248-11E8-B48F-1D18A9856A87
  last_name: Schlögl
  orcid: 0000-0002-5621-8100
- first_name: Peter M
  full_name: Jonas, Peter M
  id: 353C1B58-F248-11E8-B48F-1D18A9856A87
  last_name: Jonas
  orcid: 0000-0001-5001-4804
citation:
  ama: Zhang X, Schlögl A, Jonas PM. Selective routing of spatial information flow
    from input to output in hippocampal granule cells. <i>Neuron</i>. 2020;107(6):1212-1225.
    doi:<a href="https://doi.org/10.1016/j.neuron.2020.07.006">10.1016/j.neuron.2020.07.006</a>
  apa: Zhang, X., Schlögl, A., &#38; Jonas, P. M. (2020). Selective routing of spatial
    information flow from input to output in hippocampal granule cells. <i>Neuron</i>.
    Elsevier. <a href="https://doi.org/10.1016/j.neuron.2020.07.006">https://doi.org/10.1016/j.neuron.2020.07.006</a>
  chicago: Zhang, Xiaomin, Alois Schlögl, and Peter M Jonas. “Selective Routing of
    Spatial Information Flow from Input to Output in Hippocampal Granule Cells.” <i>Neuron</i>.
    Elsevier, 2020. <a href="https://doi.org/10.1016/j.neuron.2020.07.006">https://doi.org/10.1016/j.neuron.2020.07.006</a>.
  ieee: X. Zhang, A. Schlögl, and P. M. Jonas, “Selective routing of spatial information
    flow from input to output in hippocampal granule cells,” <i>Neuron</i>, vol. 107,
    no. 6. Elsevier, pp. 1212–1225, 2020.
  ista: Zhang X, Schlögl A, Jonas PM. 2020. Selective routing of spatial information
    flow from input to output in hippocampal granule cells. Neuron. 107(6), 1212–1225.
  mla: Zhang, Xiaomin, et al. “Selective Routing of Spatial Information Flow from
    Input to Output in Hippocampal Granule Cells.” <i>Neuron</i>, vol. 107, no. 6,
    Elsevier, 2020, pp. 1212–25, doi:<a href="https://doi.org/10.1016/j.neuron.2020.07.006">10.1016/j.neuron.2020.07.006</a>.
  short: X. Zhang, A. Schlögl, P.M. Jonas, Neuron 107 (2020) 1212–1225.
date_created: 2020-08-14T09:36:05Z
date_published: 2020-09-23T00:00:00Z
date_updated: 2023-08-22T08:30:55Z
day: '23'
ddc:
- '570'
department:
- _id: PeJo
- _id: ScienComp
doi: 10.1016/j.neuron.2020.07.006
ec_funded: 1
external_id:
  isi:
  - '000579698700009'
  pmid:
  - '32763145'
file:
- access_level: open_access
  checksum: 44a5960fc083a4cb3488d22224859fdc
  content_type: application/pdf
  creator: dernst
  date_created: 2020-12-04T09:29:21Z
  date_updated: 2020-12-04T09:29:21Z
  file_id: '8920'
  file_name: 2020_Neuron_Zhang.pdf
  file_size: 3011120
  relation: main_file
  success: 1
file_date_updated: 2020-12-04T09:29:21Z
has_accepted_license: '1'
intvolume: '       107'
isi: 1
issue: '6'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
page: 1212-1225
pmid: 1
project:
- _id: 25B7EB9E-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '692692'
  name: Biophysics and circuit function of a giant cortical glumatergic synapse
- _id: 25C5A090-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: Z00312
  name: The Wittgenstein Prize
publication: Neuron
publication_identifier:
  issn:
  - 0896-6273
publication_status: published
publisher: Elsevier
quality_controlled: '1'
related_material:
  link:
  - description: News on IST Website
    relation: press_release
    url: https://ist.ac.at/en/news/the-bouncer-in-the-brain/
status: public
title: Selective routing of spatial information flow from input to output in hippocampal
  granule cells
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 107
year: '2020'
...
---
_id: '8268'
abstract:
- lang: eng
  text: 'Modern scientific instruments produce vast amounts of data, which can overwhelm
    the processing ability of computer systems. Lossy compression of data is an intriguing
    solution, but comes with its own drawbacks, such as potential signal loss, and
    the need for careful optimization of the compression ratio. In this work, we focus
    on a setting where this problem is especially acute: compressive sensing frameworks
    for interferometry and medical imaging. We ask the following question: can the
    precision of the data representation be lowered for all inputs, with recovery
    guarantees and practical performance Our first contribution is a theoretical analysis
    of the normalized Iterative Hard Thresholding (IHT) algorithm when all input data,
    meaning both the measurement matrix and the observation vector are quantized aggressively.
    We present a variant of low precision normalized IHT that, under mild conditions,
    can still provide recovery guarantees. The second contribution is the application
    of our quantization framework to radio astronomy and magnetic resonance imaging.
    We show that lowering the precision of the data can significantly accelerate image
    recovery. We evaluate our approach on telescope data and samples of brain images
    using CPU and FPGA implementations achieving up to a 9x speedup with negligible
    loss of recovery quality.'
acknowledgement: The authors would like to thank Dr. Michiel Brentjens at the Netherlands
  Institute for Radio Astronomy (ASTRON) for providing radio interferometer data and
  Dr. Josip Marjanovic and Dr. Franciszek Hennel at the Magnetic Resonance Technology
  of ETH Zurich for providing their insights on the experiments. CZ and the DS3Lab
  gratefully acknowledge the support from the Swiss Data Science Center, Alibaba,
  Google Focused Research Awards, Huawei, MeteoSwiss, Oracle Labs, Swisscom, Zurich
  Insurance, Chinese Scholarship Council, and the Department of Computer Science at
  ETH Zurich.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Nezihe Merve
  full_name: Gurel, Nezihe Merve
  last_name: Gurel
- first_name: Kaan
  full_name: Kara, Kaan
  last_name: Kara
- first_name: Alen
  full_name: Stojanov, Alen
  last_name: Stojanov
- first_name: Tyler
  full_name: Smith, Tyler
  last_name: Smith
- first_name: Thomas
  full_name: Lemmin, Thomas
  last_name: Lemmin
- first_name: Dan-Adrian
  full_name: Alistarh, Dan-Adrian
  id: 4A899BFC-F248-11E8-B48F-1D18A9856A87
  last_name: Alistarh
  orcid: 0000-0003-3650-940X
- first_name: Markus
  full_name: Puschel, Markus
  last_name: Puschel
- first_name: Ce
  full_name: Zhang, Ce
  last_name: Zhang
citation:
  ama: 'Gurel NM, Kara K, Stojanov A, et al. Compressive sensing using iterative hard
    thresholding with low precision data representation: Theory and applications.
    <i>IEEE Transactions on Signal Processing</i>. 2020;68:4268-4282. doi:<a href="https://doi.org/10.1109/TSP.2020.3010355">10.1109/TSP.2020.3010355</a>'
  apa: 'Gurel, N. M., Kara, K., Stojanov, A., Smith, T., Lemmin, T., Alistarh, D.-A.,
    … Zhang, C. (2020). Compressive sensing using iterative hard thresholding with
    low precision data representation: Theory and applications. <i>IEEE Transactions
    on Signal Processing</i>. IEEE. <a href="https://doi.org/10.1109/TSP.2020.3010355">https://doi.org/10.1109/TSP.2020.3010355</a>'
  chicago: 'Gurel, Nezihe Merve, Kaan Kara, Alen Stojanov, Tyler Smith, Thomas Lemmin,
    Dan-Adrian Alistarh, Markus Puschel, and Ce Zhang. “Compressive Sensing Using
    Iterative Hard Thresholding with Low Precision Data Representation: Theory and
    Applications.” <i>IEEE Transactions on Signal Processing</i>. IEEE, 2020. <a href="https://doi.org/10.1109/TSP.2020.3010355">https://doi.org/10.1109/TSP.2020.3010355</a>.'
  ieee: 'N. M. Gurel <i>et al.</i>, “Compressive sensing using iterative hard thresholding
    with low precision data representation: Theory and applications,” <i>IEEE Transactions
    on Signal Processing</i>, vol. 68. IEEE, pp. 4268–4282, 2020.'
  ista: 'Gurel NM, Kara K, Stojanov A, Smith T, Lemmin T, Alistarh D-A, Puschel M,
    Zhang C. 2020. Compressive sensing using iterative hard thresholding with low
    precision data representation: Theory and applications. IEEE Transactions on Signal
    Processing. 68, 4268–4282.'
  mla: 'Gurel, Nezihe Merve, et al. “Compressive Sensing Using Iterative Hard Thresholding
    with Low Precision Data Representation: Theory and Applications.” <i>IEEE Transactions
    on Signal Processing</i>, vol. 68, IEEE, 2020, pp. 4268–82, doi:<a href="https://doi.org/10.1109/TSP.2020.3010355">10.1109/TSP.2020.3010355</a>.'
  short: N.M. Gurel, K. Kara, A. Stojanov, T. Smith, T. Lemmin, D.-A. Alistarh, M.
    Puschel, C. Zhang, IEEE Transactions on Signal Processing 68 (2020) 4268–4282.
date_created: 2020-08-16T22:00:56Z
date_published: 2020-07-20T00:00:00Z
date_updated: 2023-08-22T08:40:08Z
day: '20'
department:
- _id: DaAl
doi: 10.1109/TSP.2020.3010355
external_id:
  arxiv:
  - '1802.04907'
  isi:
  - '000562044500001'
intvolume: '        68'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1802.04907
month: '07'
oa: 1
oa_version: Preprint
page: 4268-4282
publication: IEEE Transactions on Signal Processing
publication_identifier:
  eissn:
  - '19410476'
  issn:
  - 1053587X
publication_status: published
publisher: IEEE
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Compressive sensing using iterative hard thresholding with low precision data
  representation: Theory and applications'
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 68
year: '2020'
...
---
_id: '8271'
acknowledgement: We thank Dr. Gai Huang for his comments and help. We apologize to
  authors whose work could not be cited due to space limitation. No conflict of interest
  declared.
article_processing_charge: No
article_type: original
author:
- first_name: Peng
  full_name: He, Peng
  last_name: He
- first_name: Yuzhou
  full_name: Zhang, Yuzhou
  id: 3B6137F2-F248-11E8-B48F-1D18A9856A87
  last_name: Zhang
  orcid: 0000-0003-2627-6956
- first_name: Guanghui
  full_name: Xiao, Guanghui
  last_name: Xiao
citation:
  ama: He P, Zhang Y, Xiao G. Origin of a subgenome and genome evolution of allotetraploid
    cotton species. <i>Molecular Plant</i>. 2020;13(9):1238-1240. doi:<a href="https://doi.org/10.1016/j.molp.2020.07.006">10.1016/j.molp.2020.07.006</a>
  apa: He, P., Zhang, Y., &#38; Xiao, G. (2020). Origin of a subgenome and genome
    evolution of allotetraploid cotton species. <i>Molecular Plant</i>. Elsevier.
    <a href="https://doi.org/10.1016/j.molp.2020.07.006">https://doi.org/10.1016/j.molp.2020.07.006</a>
  chicago: He, Peng, Yuzhou Zhang, and Guanghui Xiao. “Origin of a Subgenome and Genome
    Evolution of Allotetraploid Cotton Species.” <i>Molecular Plant</i>. Elsevier,
    2020. <a href="https://doi.org/10.1016/j.molp.2020.07.006">https://doi.org/10.1016/j.molp.2020.07.006</a>.
  ieee: P. He, Y. Zhang, and G. Xiao, “Origin of a subgenome and genome evolution
    of allotetraploid cotton species,” <i>Molecular Plant</i>, vol. 13, no. 9. Elsevier,
    pp. 1238–1240, 2020.
  ista: He P, Zhang Y, Xiao G. 2020. Origin of a subgenome and genome evolution of
    allotetraploid cotton species. Molecular Plant. 13(9), 1238–1240.
  mla: He, Peng, et al. “Origin of a Subgenome and Genome Evolution of Allotetraploid
    Cotton Species.” <i>Molecular Plant</i>, vol. 13, no. 9, Elsevier, 2020, pp. 1238–40,
    doi:<a href="https://doi.org/10.1016/j.molp.2020.07.006">10.1016/j.molp.2020.07.006</a>.
  short: P. He, Y. Zhang, G. Xiao, Molecular Plant 13 (2020) 1238–1240.
date_created: 2020-08-16T22:00:57Z
date_published: 2020-09-07T00:00:00Z
date_updated: 2023-08-22T08:40:35Z
day: '07'
department:
- _id: JiFr
doi: 10.1016/j.molp.2020.07.006
external_id:
  isi:
  - '000566895400007'
  pmid:
  - '32688032'
intvolume: '        13'
isi: 1
issue: '9'
language:
- iso: eng
month: '09'
oa_version: None
page: 1238-1240
pmid: 1
publication: Molecular Plant
publication_identifier:
  eissn:
  - '17529867'
  issn:
  - '16742052'
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Origin of a subgenome and genome evolution of allotetraploid cotton species
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 13
year: '2020'
...
---
_id: '8272'
abstract:
- lang: eng
  text: We study turn-based stochastic zero-sum games with lexicographic preferences
    over reachability and safety objectives. Stochastic games are standard models
    in control, verification, and synthesis of stochastic reactive systems that exhibit
    both randomness as well as angelic and demonic non-determinism. Lexicographic
    order allows to consider multiple objectives with a strict preference order over
    the satisfaction of the objectives. To the best of our knowledge, stochastic games
    with lexicographic objectives have not been studied before. We establish determinacy
    of such games and present strategy and computational complexity results. For strategy
    complexity, we show that lexicographically optimal strategies exist that are deterministic
    and memory is only required to remember the already satisfied and violated objectives.
    For a constant number of objectives, we show that the relevant decision problem
    is in   NP∩coNP , matching the current known bound for single objectives; and
    in general the decision problem is   PSPACE -hard and can be solved in   NEXPTIME∩coNEXPTIME
    . We present an algorithm that computes the lexicographically optimal strategies
    via a reduction to computation of optimal strategies in a sequence of single-objectives
    games. We have implemented our algorithm and report experimental results on various
    case studies.
alternative_title:
- LNCS
article_processing_charge: No
arxiv: 1
author:
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Joost P
  full_name: Katoen, Joost P
  id: 4524F760-F248-11E8-B48F-1D18A9856A87
  last_name: Katoen
- first_name: Maximilian
  full_name: Weininger, Maximilian
  last_name: Weininger
- first_name: Tobias
  full_name: Winkler, Tobias
  last_name: Winkler
citation:
  ama: 'Chatterjee K, Katoen JP, Weininger M, Winkler T. Stochastic games with lexicographic
    reachability-safety objectives. In: <i>International Conference on Computer Aided
    Verification</i>. Vol 12225. Springer Nature; 2020:398-420. doi:<a href="https://doi.org/10.1007/978-3-030-53291-8_21">10.1007/978-3-030-53291-8_21</a>'
  apa: Chatterjee, K., Katoen, J. P., Weininger, M., &#38; Winkler, T. (2020). Stochastic
    games with lexicographic reachability-safety objectives. In <i>International Conference
    on Computer Aided Verification</i> (Vol. 12225, pp. 398–420). Springer Nature.
    <a href="https://doi.org/10.1007/978-3-030-53291-8_21">https://doi.org/10.1007/978-3-030-53291-8_21</a>
  chicago: Chatterjee, Krishnendu, Joost P Katoen, Maximilian Weininger, and Tobias
    Winkler. “Stochastic Games with Lexicographic Reachability-Safety Objectives.”
    In <i>International Conference on Computer Aided Verification</i>, 12225:398–420.
    Springer Nature, 2020. <a href="https://doi.org/10.1007/978-3-030-53291-8_21">https://doi.org/10.1007/978-3-030-53291-8_21</a>.
  ieee: K. Chatterjee, J. P. Katoen, M. Weininger, and T. Winkler, “Stochastic games
    with lexicographic reachability-safety objectives,” in <i>International Conference
    on Computer Aided Verification</i>, 2020, vol. 12225, pp. 398–420.
  ista: 'Chatterjee K, Katoen JP, Weininger M, Winkler T. 2020. Stochastic games with
    lexicographic reachability-safety objectives. International Conference on Computer
    Aided Verification. CAV: Computer Aided Verification, LNCS, vol. 12225, 398–420.'
  mla: Chatterjee, Krishnendu, et al. “Stochastic Games with Lexicographic Reachability-Safety
    Objectives.” <i>International Conference on Computer Aided Verification</i>, vol.
    12225, Springer Nature, 2020, pp. 398–420, doi:<a href="https://doi.org/10.1007/978-3-030-53291-8_21">10.1007/978-3-030-53291-8_21</a>.
  short: K. Chatterjee, J.P. Katoen, M. Weininger, T. Winkler, in:, International
    Conference on Computer Aided Verification, Springer Nature, 2020, pp. 398–420.
conference:
  name: 'CAV: Computer Aided Verification'
date_created: 2020-08-16T22:00:58Z
date_published: 2020-07-14T00:00:00Z
date_updated: 2025-07-14T09:10:14Z
day: '14'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.1007/978-3-030-53291-8_21
ec_funded: 1
external_id:
  arxiv:
  - '2005.04018'
  isi:
  - '000695272500021'
file:
- access_level: open_access
  checksum: 093d4788d7d5b2ce0ffe64fbe7820043
  content_type: application/pdf
  creator: dernst
  date_created: 2020-08-17T11:32:44Z
  date_updated: 2020-08-17T11:32:44Z
  file_id: '8276'
  file_name: 2020_LNCS_CAV_Chatterjee.pdf
  file_size: 625056
  relation: main_file
  success: 1
file_date_updated: 2020-08-17T11:32:44Z
has_accepted_license: '1'
intvolume: '     12225'
isi: 1
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: 398-420
project:
- _id: 0599E47C-7A3F-11EA-A408-12923DDC885E
  call_identifier: H2020
  grant_number: '863818'
  name: 'Formal Methods for Stochastic Models: Algorithms and Applications'
- _id: 25892FC0-B435-11E9-9278-68D0E5697425
  grant_number: ICT15-003
  name: Efficient Algorithms for Computer Aided Verification
publication: International Conference on Computer Aided Verification
publication_identifier:
  eissn:
  - '16113349'
  isbn:
  - '9783030532901'
  issn:
  - '03029743'
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
  record:
  - id: '12738'
    relation: later_version
    status: public
scopus_import: '1'
status: public
title: Stochastic games with lexicographic reachability-safety objectives
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: conference
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 12225
year: '2020'
...
---
_id: '8283'
abstract:
- lang: eng
  text: 'Drought and salt stress are the main environmental cues affecting the survival,
    development, distribution, and yield of crops worldwide. MYB transcription factors
    play a crucial role in plants’ biological processes, but the function of pineapple
    MYB genes is still obscure. In this study, one of the pineapple MYB transcription
    factors, AcoMYB4, was isolated and characterized. The results showed that AcoMYB4
    is localized in the cell nucleus, and its expression is induced by low temperature,
    drought, salt stress, and hormonal stimulation, especially by abscisic acid (ABA).
    Overexpression of AcoMYB4 in rice and Arabidopsis enhanced plant sensitivity to
    osmotic stress; it led to an increase in the number stomata on leaf surfaces and
    lower germination rate under salt and drought stress. Furthermore, in AcoMYB4
    OE lines, the membrane oxidation index, free proline, and soluble sugar contents
    were decreased. In contrast, electrolyte leakage and malondialdehyde (MDA) content
    increased significantly due to membrane injury, indicating higher sensitivity
    to drought and salinity stresses. Besides the above, both the expression level
    and activities of several antioxidant enzymes were decreased, indicating lower
    antioxidant activity in AcoMYB4 transgenic plants. Moreover, under osmotic stress,
    overexpression of AcoMYB4 inhibited ABA biosynthesis through a decrease in the
    transcription of genes responsible for ABA synthesis (ABA1 and ABA2) and ABA signal
    transduction factor ABI5. These results suggest that AcoMYB4 negatively regulates
    osmotic stress by attenuating cellular ABA biosynthesis and signal transduction
    pathways. '
acknowledgement: 'We would like to thank the reviewers for their helpful comments
  on the original manuscript. '
article_number: '5272'
article_processing_charge: No
article_type: original
author:
- first_name: Huihuang
  full_name: Chen, Huihuang
  last_name: Chen
- first_name: Linyi
  full_name: Lai, Linyi
  last_name: Lai
- first_name: Lanxin
  full_name: Li, Lanxin
  id: 367EF8FA-F248-11E8-B48F-1D18A9856A87
  last_name: Li
  orcid: 0000-0002-5607-272X
- first_name: Liping
  full_name: Liu, Liping
  last_name: Liu
- first_name: Bello Hassan
  full_name: Jakada, Bello Hassan
  last_name: Jakada
- first_name: Youmei
  full_name: Huang, Youmei
  last_name: Huang
- first_name: Qing
  full_name: He, Qing
  last_name: He
- first_name: Mengnan
  full_name: Chai, Mengnan
  last_name: Chai
- first_name: Xiaoping
  full_name: Niu, Xiaoping
  last_name: Niu
- first_name: Yuan
  full_name: Qin, Yuan
  last_name: Qin
citation:
  ama: Chen H, Lai L, Li L, et al. AcoMYB4, an Ananas comosus L. MYB transcription
    factor, functions in osmotic stress through negative regulation of ABA signaling.
    <i>International Journal of Molecular Sciences</i>. 2020;21(16). doi:<a href="https://doi.org/10.3390/ijms21165727">10.3390/ijms21165727</a>
  apa: Chen, H., Lai, L., Li, L., Liu, L., Jakada, B. H., Huang, Y., … Qin, Y. (2020).
    AcoMYB4, an Ananas comosus L. MYB transcription factor, functions in osmotic stress
    through negative regulation of ABA signaling. <i>International Journal of Molecular
    Sciences</i>. MDPI. <a href="https://doi.org/10.3390/ijms21165727">https://doi.org/10.3390/ijms21165727</a>
  chicago: Chen, Huihuang, Linyi Lai, Lanxin Li, Liping Liu, Bello Hassan Jakada,
    Youmei Huang, Qing He, Mengnan Chai, Xiaoping Niu, and Yuan Qin. “AcoMYB4, an
    Ananas Comosus L. MYB Transcription Factor, Functions in Osmotic Stress through
    Negative Regulation of ABA Signaling.” <i>International Journal of Molecular Sciences</i>.
    MDPI, 2020. <a href="https://doi.org/10.3390/ijms21165727">https://doi.org/10.3390/ijms21165727</a>.
  ieee: H. Chen <i>et al.</i>, “AcoMYB4, an Ananas comosus L. MYB transcription factor,
    functions in osmotic stress through negative regulation of ABA signaling,” <i>International
    Journal of Molecular Sciences</i>, vol. 21, no. 16. MDPI, 2020.
  ista: Chen H, Lai L, Li L, Liu L, Jakada BH, Huang Y, He Q, Chai M, Niu X, Qin Y.
    2020. AcoMYB4, an Ananas comosus L. MYB transcription factor, functions in osmotic
    stress through negative regulation of ABA signaling. International Journal of
    Molecular Sciences. 21(16), 5272.
  mla: Chen, Huihuang, et al. “AcoMYB4, an Ananas Comosus L. MYB Transcription Factor,
    Functions in Osmotic Stress through Negative Regulation of ABA Signaling.” <i>International
    Journal of Molecular Sciences</i>, vol. 21, no. 16, 5272, MDPI, 2020, doi:<a href="https://doi.org/10.3390/ijms21165727">10.3390/ijms21165727</a>.
  short: H. Chen, L. Lai, L. Li, L. Liu, B.H. Jakada, Y. Huang, Q. He, M. Chai, X.
    Niu, Y. Qin, International Journal of Molecular Sciences 21 (2020).
date_created: 2020-08-24T06:24:03Z
date_published: 2020-08-10T00:00:00Z
date_updated: 2024-10-29T10:22:43Z
day: '10'
ddc:
- '570'
department:
- _id: JiFr
doi: 10.3390/ijms21165727
external_id:
  isi:
  - '000565090300001'
  pmid:
  - '32785037'
file:
- access_level: open_access
  checksum: 03b039244e6ae80580385fd9f577e2b2
  content_type: application/pdf
  creator: cziletti
  date_created: 2020-08-25T09:53:50Z
  date_updated: 2020-08-25T09:53:50Z
  file_id: '8292'
  file_name: 2020_IntMolecSciences_Chen.pdf
  file_size: 5718755
  relation: main_file
  success: 1
file_date_updated: 2020-08-25T09:53:50Z
has_accepted_license: '1'
intvolume: '        21'
isi: 1
issue: '16'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
pmid: 1
publication: International Journal of Molecular Sciences
publication_identifier:
  eissn:
  - '14220067'
  issn:
  - '16616596'
publication_status: published
publisher: MDPI
quality_controlled: '1'
related_material:
  record:
  - id: '10083'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: AcoMYB4, an Ananas comosus L. MYB transcription factor, functions in osmotic
  stress through negative regulation of ABA signaling
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 21
year: '2020'
...
---
_id: '8284'
abstract:
- lang: eng
  text: Multiple resistance and pH adaptation (Mrp) antiporters are multi-subunit
    Na+ (or K+)/H+ exchangers representing an ancestor of many essential redox-driven
    proton pumps, such as respiratory complex I. The mechanism of coupling between
    ion or electron transfer and proton translocation in this large protein family
    is unknown. Here, we present the structure of the Mrp complex from Anoxybacillus
    flavithermus solved by cryo-EM at 3.0 Å resolution. It is a dimer of seven-subunit
    protomers with 50 trans-membrane helices each. Surface charge distribution within
    each monomer is remarkably asymmetric, revealing probable proton and sodium translocation
    pathways. On the basis of the structure we propose a mechanism where the coupling
    between sodium and proton translocation is facilitated by a series of electrostatic
    interactions between a cation and key charged residues. This mechanism is likely
    to be applicable to the entire family of redox proton pumps, where electron transfer
    to substrates replaces cation movements.
acknowledged_ssus:
- _id: EM-Fac
- _id: LifeSc
acknowledgement: This research was supported by the Scientific Service Units (SSU)
  of IST Austria through resources provided by the Electron Microscopy Facility (EMF),
  the Life Science Facility (LSF) and the IST high-performance computing cluster.
  We thank Dr Victor-Valentin Hodirnau and Daniel Johann Gütl from IST Austria for
  assistance with collecting cryo-EM data. We thank Prof. Masahiro Ito (Graduate School
  of Life Sciences, Toyo University, Japan) for a kind provision of plasmid DNA encoding
  Mrp from A. flavithermus WK1. JS is a recipient of a DOC Fellowship of the Austrian
  Academy of Sciences at the Institute of Science and Technology, Austria.
article_number: e59407
article_processing_charge: No
article_type: original
author:
- first_name: Julia
  full_name: Steiner, Julia
  id: 3BB67EB0-F248-11E8-B48F-1D18A9856A87
  last_name: Steiner
  orcid: 0000-0003-0493-3775
- first_name: Leonid A
  full_name: Sazanov, Leonid A
  id: 338D39FE-F248-11E8-B48F-1D18A9856A87
  last_name: Sazanov
  orcid: 0000-0002-0977-7989
citation:
  ama: Steiner J, Sazanov LA. Structure and mechanism of the Mrp complex, an ancient
    cation/proton antiporter. <i>eLife</i>. 2020;9. doi:<a href="https://doi.org/10.7554/eLife.59407">10.7554/eLife.59407</a>
  apa: Steiner, J., &#38; Sazanov, L. A. (2020). Structure and mechanism of the Mrp
    complex, an ancient cation/proton antiporter. <i>ELife</i>. eLife Sciences Publications.
    <a href="https://doi.org/10.7554/eLife.59407">https://doi.org/10.7554/eLife.59407</a>
  chicago: Steiner, Julia, and Leonid A Sazanov. “Structure and Mechanism of the Mrp
    Complex, an Ancient Cation/Proton Antiporter.” <i>ELife</i>. eLife Sciences Publications,
    2020. <a href="https://doi.org/10.7554/eLife.59407">https://doi.org/10.7554/eLife.59407</a>.
  ieee: J. Steiner and L. A. Sazanov, “Structure and mechanism of the Mrp complex,
    an ancient cation/proton antiporter,” <i>eLife</i>, vol. 9. eLife Sciences Publications,
    2020.
  ista: Steiner J, Sazanov LA. 2020. Structure and mechanism of the Mrp complex, an
    ancient cation/proton antiporter. eLife. 9, e59407.
  mla: Steiner, Julia, and Leonid A. Sazanov. “Structure and Mechanism of the Mrp
    Complex, an Ancient Cation/Proton Antiporter.” <i>ELife</i>, vol. 9, e59407, eLife
    Sciences Publications, 2020, doi:<a href="https://doi.org/10.7554/eLife.59407">10.7554/eLife.59407</a>.
  short: J. Steiner, L.A. Sazanov, ELife 9 (2020).
date_created: 2020-08-24T06:24:04Z
date_published: 2020-07-31T00:00:00Z
date_updated: 2023-09-07T13:14:08Z
day: '31'
ddc:
- '570'
department:
- _id: LeSa
doi: 10.7554/eLife.59407
external_id:
  isi:
  - '000562123600001'
  pmid:
  - '32735215'
file:
- access_level: open_access
  checksum: b3656d14d5ddbb9d26e3074eea2d0c15
  content_type: application/pdf
  creator: cziletti
  date_created: 2020-08-24T13:31:53Z
  date_updated: 2020-08-24T13:31:53Z
  file_id: '8289'
  file_name: 2020_eLife_Steiner.pdf
  file_size: 7320493
  relation: main_file
  success: 1
file_date_updated: 2020-08-24T13:31:53Z
has_accepted_license: '1'
intvolume: '         9'
isi: 1
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 26169496-B435-11E9-9278-68D0E5697425
  grant_number: '24741'
  name: Revealing the functional mechanism of Mrp antiporter, an ancestor of complex
    I
publication: eLife
publication_identifier:
  eissn:
  - 2050084X
publication_status: published
publisher: eLife Sciences Publications
quality_controlled: '1'
related_material:
  link:
  - description: News on IST Homepage
    relation: press_release
    url: https://ist.ac.at/en/news/mystery-of-giant-proton-pump-solved/
  record:
  - id: '8353'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: Structure and mechanism of the Mrp complex, an ancient cation/proton antiporter
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 9
year: '2020'
...
---
_id: '8285'
abstract:
- lang: eng
  text: We demonstrate the utility of optical cavity generated spin-squeezed states
    in free space atomic fountain clocks in ensembles of 390 000 87Rb atoms. Fluorescence
    imaging, correlated to an initial quantum nondemolition measurement, is used for
    population spectroscopy after the atoms are released from a confining lattice.
    For a free fall time of 4 milliseconds, we resolve a single-shot phase sensitivity
    of 814(61) microradians, which is 5.8(0.6) decibels (dB) below the quantum projection
    limit. We observe that this squeezing is preserved as the cloud expands to a roughly
    200  μm radius and falls roughly 300  μm in free space. Ramsey spectroscopy with
    240 000 atoms at a 3.6 ms Ramsey time results in a single-shot fractional frequency
    stability of 8.4(0.2)×10−12, 3.8(0.2) dB below the quantum projection limit. The
    sensitivity and stability are limited by the technical noise in the fluorescence
    detection protocol and the microwave system, respectively.
acknowledgement: This work is supported by the Office of Naval Research (N00014-16-1-2927-
  A00003), Vannevar Bush Faculty Fellowship (N00014-16-1-2812- P00005), Department
  of Energy (DE-SC0019174- 0001), and Defense Threat Reduction Agency (HDTRA1-15-1-0017-
  P00005).
article_number: '043202'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Benjamin K.
  full_name: Malia, Benjamin K.
  last_name: Malia
- first_name: Julián
  full_name: Martínez-Rincón, Julián
  last_name: Martínez-Rincón
- first_name: Yunfan
  full_name: Wu, Yunfan
  last_name: Wu
- first_name: Onur
  full_name: Hosten, Onur
  id: 4C02D85E-F248-11E8-B48F-1D18A9856A87
  last_name: Hosten
  orcid: 0000-0002-2031-204X
- first_name: Mark A.
  full_name: Kasevich, Mark A.
  last_name: Kasevich
citation:
  ama: Malia BK, Martínez-Rincón J, Wu Y, Hosten O, Kasevich MA. Free space Ramsey
    spectroscopy in rubidium with noise below the quantum projection limit. <i>Physical
    Review Letters</i>. 2020;125(4). doi:<a href="https://doi.org/10.1103/PhysRevLett.125.043202">10.1103/PhysRevLett.125.043202</a>
  apa: Malia, B. K., Martínez-Rincón, J., Wu, Y., Hosten, O., &#38; Kasevich, M. A.
    (2020). Free space Ramsey spectroscopy in rubidium with noise below the quantum
    projection limit. <i>Physical Review Letters</i>. American Physical Society. <a
    href="https://doi.org/10.1103/PhysRevLett.125.043202">https://doi.org/10.1103/PhysRevLett.125.043202</a>
  chicago: Malia, Benjamin K., Julián Martínez-Rincón, Yunfan Wu, Onur Hosten, and
    Mark A. Kasevich. “Free Space Ramsey Spectroscopy in Rubidium with Noise below
    the Quantum Projection Limit.” <i>Physical Review Letters</i>. American Physical
    Society, 2020. <a href="https://doi.org/10.1103/PhysRevLett.125.043202">https://doi.org/10.1103/PhysRevLett.125.043202</a>.
  ieee: B. K. Malia, J. Martínez-Rincón, Y. Wu, O. Hosten, and M. A. Kasevich, “Free
    space Ramsey spectroscopy in rubidium with noise below the quantum projection
    limit,” <i>Physical Review Letters</i>, vol. 125, no. 4. American Physical Society,
    2020.
  ista: Malia BK, Martínez-Rincón J, Wu Y, Hosten O, Kasevich MA. 2020. Free space
    Ramsey spectroscopy in rubidium with noise below the quantum projection limit.
    Physical Review Letters. 125(4), 043202.
  mla: Malia, Benjamin K., et al. “Free Space Ramsey Spectroscopy in Rubidium with
    Noise below the Quantum Projection Limit.” <i>Physical Review Letters</i>, vol.
    125, no. 4, 043202, American Physical Society, 2020, doi:<a href="https://doi.org/10.1103/PhysRevLett.125.043202">10.1103/PhysRevLett.125.043202</a>.
  short: B.K. Malia, J. Martínez-Rincón, Y. Wu, O. Hosten, M.A. Kasevich, Physical
    Review Letters 125 (2020).
date_created: 2020-08-24T06:24:04Z
date_published: 2020-07-24T00:00:00Z
date_updated: 2023-10-18T08:38:35Z
day: '24'
department:
- _id: OnHo
doi: 10.1103/PhysRevLett.125.043202
external_id:
  arxiv:
  - '1912.10218'
  isi:
  - '000552227400008'
  pmid:
  - '32794788'
intvolume: '       125'
isi: 1
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1912.10218
month: '07'
oa: 1
oa_version: Preprint
pmid: 1
publication: Physical Review Letters
publication_identifier:
  eissn:
  - 1079-7114
  issn:
  - 0031-9007
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Free space Ramsey spectroscopy in rubidium with noise below the quantum projection
  limit
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 125
year: '2020'
...
---
_id: '8287'
abstract:
- lang: eng
  text: Reachability analysis aims at identifying states reachable by a system within
    a given time horizon. This task is known to be computationally expensive for linear
    hybrid systems. Reachability analysis works by iteratively applying continuous
    and discrete post operators to compute states reachable according to continuous
    and discrete dynamics, respectively. In this paper, we enhance both of these operators
    and make sure that most of the involved computations are performed in low-dimensional
    state space. In particular, we improve the continuous-post operator by performing
    computations in high-dimensional state space only for time intervals relevant
    for the subsequent application of the discrete-post operator. Furthermore, the
    new discrete-post operator performs low-dimensional computations by leveraging
    the structure of the guard and assignment of a considered transition. We illustrate
    the potential of our approach on a number of challenging benchmarks.
article_processing_charge: No
arxiv: 1
author:
- first_name: Sergiy
  full_name: Bogomolov, Sergiy
  last_name: Bogomolov
- first_name: Marcelo
  full_name: Forets, Marcelo
  last_name: Forets
- first_name: Goran
  full_name: Frehse, Goran
  last_name: Frehse
- first_name: Kostiantyn
  full_name: Potomkin, Kostiantyn
  last_name: Potomkin
- first_name: Christian
  full_name: Schilling, Christian
  id: 3A2F4DCE-F248-11E8-B48F-1D18A9856A87
  last_name: Schilling
  orcid: 0000-0003-3658-1065
citation:
  ama: 'Bogomolov S, Forets M, Frehse G, Potomkin K, Schilling C. Reachability analysis
    of linear hybrid systems via block decomposition. In: <i>Proceedings of the International
    Conference on Embedded Software</i>. ; 2020.'
  apa: Bogomolov, S., Forets, M., Frehse, G., Potomkin, K., &#38; Schilling, C. (2020).
    Reachability analysis of linear hybrid systems via block decomposition. In <i>Proceedings
    of the International Conference on Embedded Software</i>. Virtual .
  chicago: Bogomolov, Sergiy, Marcelo Forets, Goran Frehse, Kostiantyn Potomkin, and
    Christian Schilling. “Reachability Analysis of Linear Hybrid Systems via Block
    Decomposition.” In <i>Proceedings of the International Conference on Embedded
    Software</i>, 2020.
  ieee: S. Bogomolov, M. Forets, G. Frehse, K. Potomkin, and C. Schilling, “Reachability
    analysis of linear hybrid systems via block decomposition,” in <i>Proceedings
    of the International Conference on Embedded Software</i>, Virtual , 2020.
  ista: 'Bogomolov S, Forets M, Frehse G, Potomkin K, Schilling C. 2020. Reachability
    analysis of linear hybrid systems via block decomposition. Proceedings of the
    International Conference on Embedded Software. EMSOFT: International Conference
    on Embedded Software.'
  mla: Bogomolov, Sergiy, et al. “Reachability Analysis of Linear Hybrid Systems via
    Block Decomposition.” <i>Proceedings of the International Conference on Embedded
    Software</i>, 2020.
  short: S. Bogomolov, M. Forets, G. Frehse, K. Potomkin, C. Schilling, in:, Proceedings
    of the International Conference on Embedded Software, 2020.
conference:
  end_date: 2020-09-25
  location: 'Virtual '
  name: 'EMSOFT: International Conference on Embedded Software'
  start_date: 2020-09-20
date_created: 2020-08-24T12:56:20Z
date_published: 2020-01-01T00:00:00Z
date_updated: 2023-08-22T13:27:32Z
ddc:
- '000'
department:
- _id: ToHe
ec_funded: 1
external_id:
  arxiv:
  - '1905.02458'
file:
- access_level: open_access
  checksum: d19e97d0f8a3a441dc078ec812297d75
  content_type: application/pdf
  creator: cschilli
  date_created: 2020-08-24T12:53:15Z
  date_updated: 2020-08-24T12:53:15Z
  file_id: '8288'
  file_name: 2020EMSOFT.pdf
  file_size: 696384
  relation: main_file
  success: 1
file_date_updated: 2020-08-24T12:53:15Z
has_accepted_license: '1'
keyword:
- reachability
- hybrid systems
- decomposition
language:
- iso: eng
oa: 1
oa_version: Preprint
project:
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: S 11407_N23
  name: Rigorous Systems Engineering
- _id: 25C5A090-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: Z00312
  name: The Wittgenstein Prize
- _id: 260C2330-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '754411'
  name: ISTplus - Postdoctoral Fellowships
publication: Proceedings of the International Conference on Embedded Software
publication_status: published
quality_controlled: '1'
related_material:
  record:
  - id: '8790'
    relation: later_version
    status: public
status: public
title: Reachability analysis of linear hybrid systems via block decomposition
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: conference
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2020'
...
---
_id: '8308'
abstract:
- lang: eng
  text: 'Many-body localization provides a mechanism to avoid thermalization in isolated
    interacting quantum systems. The breakdown of thermalization may be complete,
    when all eigenstates in the many-body spectrum become localized, or partial, when
    the so-called many-body mobility edge separates localized and delocalized parts
    of the spectrum. Previously, De Roeck et al. [Phys. Rev. B 93, 014203 (2016)]
    suggested a possible instability of the many-body mobility edge in energy density.
    The local ergodic regions—so-called “bubbles”—resonantly spread throughout the
    system, leading to delocalization. In order to study such instability mechanism,
    in this work we design a model featuring many-body mobility edge in particle density:
    the states at small particle density are localized, while increasing the density
    of particles leads to delocalization. Using numerical simulations with matrix
    product states, we demonstrate the stability of many-body localization with respect
    to small bubbles in large dilute systems for experimentally relevant timescales.
    In addition, we demonstrate that processes where the bubble spreads are favored
    over processes that lead to resonant tunneling, suggesting a possible mechanism
    behind the observed stability of many-body mobility edge. We conclude by proposing
    experiments to probe particle density mobility edge in the Bose-Hubbard model.'
acknowledgement: 'Acknowledgments. We acknowledge useful discussions with W. De Roeck
  and A. Michailidis. P.B. was supported by the European Union''s Horizon 2020 research
  and innovation program under the Marie Sklodowska-Curie Grant Agreement No. 665385.
  D.A. was supported by the Swiss National Science Foundation. M.S. was supported
  by European Research Council (ERC) under the European Union''s Horizon 2020 research
  and innovation program (Grant Agreement No. 850899). This work benefited from visits
  to KITP, supported by the National Science Foundation under Grant No. NSF PHY-1748958
  and from the program “Thermalization, Many Body Localization and Hydrodynamics”
  at International Centre for Theoretical Sciences (Code: ICTS/hydrodynamics2019/11).'
article_number: 060202(R)
article_processing_charge: No
article_type: original
author:
- first_name: Pietro
  full_name: Brighi, Pietro
  id: 4115AF5C-F248-11E8-B48F-1D18A9856A87
  last_name: Brighi
  orcid: 0000-0002-7969-2729
- first_name: Dmitry A.
  full_name: Abanin, Dmitry A.
  last_name: Abanin
- first_name: Maksym
  full_name: Serbyn, Maksym
  id: 47809E7E-F248-11E8-B48F-1D18A9856A87
  last_name: Serbyn
  orcid: 0000-0002-2399-5827
citation:
  ama: Brighi P, Abanin DA, Serbyn M. Stability of mobility edges in disordered interacting
    systems. <i>Physical Review B</i>. 2020;102(6). doi:<a href="https://doi.org/10.1103/physrevb.102.060202">10.1103/physrevb.102.060202</a>
  apa: Brighi, P., Abanin, D. A., &#38; Serbyn, M. (2020). Stability of mobility edges
    in disordered interacting systems. <i>Physical Review B</i>. American Physical
    Society. <a href="https://doi.org/10.1103/physrevb.102.060202">https://doi.org/10.1103/physrevb.102.060202</a>
  chicago: Brighi, Pietro, Dmitry A. Abanin, and Maksym Serbyn. “Stability of Mobility
    Edges in Disordered Interacting Systems.” <i>Physical Review B</i>. American Physical
    Society, 2020. <a href="https://doi.org/10.1103/physrevb.102.060202">https://doi.org/10.1103/physrevb.102.060202</a>.
  ieee: P. Brighi, D. A. Abanin, and M. Serbyn, “Stability of mobility edges in disordered
    interacting systems,” <i>Physical Review B</i>, vol. 102, no. 6. American Physical
    Society, 2020.
  ista: Brighi P, Abanin DA, Serbyn M. 2020. Stability of mobility edges in disordered
    interacting systems. Physical Review B. 102(6), 060202(R).
  mla: Brighi, Pietro, et al. “Stability of Mobility Edges in Disordered Interacting
    Systems.” <i>Physical Review B</i>, vol. 102, no. 6, 060202(R), American Physical
    Society, 2020, doi:<a href="https://doi.org/10.1103/physrevb.102.060202">10.1103/physrevb.102.060202</a>.
  short: P. Brighi, D.A. Abanin, M. Serbyn, Physical Review B 102 (2020).
date_created: 2020-08-26T19:27:42Z
date_published: 2020-08-26T00:00:00Z
date_updated: 2023-08-24T14:20:21Z
day: '26'
ddc:
- '530'
department:
- _id: MaSe
doi: 10.1103/physrevb.102.060202
ec_funded: 1
external_id:
  isi:
  - '000562628300001'
file:
- access_level: open_access
  checksum: 716442fa7861323fcc80b93718ca009c
  content_type: application/pdf
  creator: mserbyn
  date_created: 2020-08-26T19:28:55Z
  date_updated: 2020-08-26T19:28:55Z
  file_id: '8309'
  file_name: PhysRevB.102.060202.pdf
  file_size: 488825
  relation: main_file
  success: 1
- access_level: open_access
  checksum: be0abdc8f60fe065ea6dc92e08487122
  content_type: application/pdf
  creator: mserbyn
  date_created: 2020-08-26T19:29:00Z
  date_updated: 2020-08-26T19:29:00Z
  file_id: '8310'
  file_name: Supplementary-mbme.pdf
  file_size: 711405
  relation: main_file
  success: 1
file_date_updated: 2020-08-26T19:29:00Z
has_accepted_license: '1'
intvolume: '       102'
isi: 1
issue: '6'
language:
- iso: eng
month: '08'
oa: 1
oa_version: None
project:
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '665385'
  name: International IST Doctoral Program
- _id: 23841C26-32DE-11EA-91FC-C7463DDC885E
  call_identifier: H2020
  grant_number: '850899'
  name: 'Non-Ergodic Quantum Matter: Universality, Dynamics and Control'
publication: Physical Review B
publication_identifier:
  eissn:
  - 2469-9969
  issn:
  - 2469-9950
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
related_material:
  record:
  - id: '12732'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: Stability of mobility edges in disordered interacting systems
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 102
year: '2020'
...
---
_id: '8318'
abstract:
- lang: eng
  text: Complex I is the first and the largest enzyme of respiratory chains in bacteria
    and mitochondria. The mechanism which couples spatially separated transfer of
    electrons to proton translocation in complex I is not known. Here we report five
    crystal structures of T. thermophilus enzyme in complex with NADH or quinone-like
    compounds. We also determined cryo-EM structures of major and minor native states
    of the complex, differing in the position of the peripheral arm. Crystal structures
    show that binding of quinone-like compounds (but not of NADH) leads to a related
    global conformational change, accompanied by local re-arrangements propagating
    from the quinone site to the nearest proton channel. Normal mode and molecular
    dynamics analyses indicate that these are likely to represent the first steps
    in the proton translocation mechanism. Our results suggest that quinone binding
    and chemistry play a key role in the coupling mechanism of complex I.
acknowledgement: This work was funded by the Medical Research Council, UK and IST
  Austria. We thank the European Synchrotron Radiation Facility and the Diamond Light
  Source for provision of synchrotron radiation facilities. We are grateful to the
  staff of beamlines ID29, ID23-2 (ESRF, Grenoble, France) and I03 (Diamond Light
  Source, Didcot, UK) for assistance. Data processing was performed at the IST high-performance
  computing cluster.
article_number: '4135'
article_processing_charge: No
article_type: original
author:
- first_name: Javier
  full_name: Gutierrez-Fernandez, Javier
  id: 3D9511BA-F248-11E8-B48F-1D18A9856A87
  last_name: Gutierrez-Fernandez
- first_name: Karol
  full_name: Kaszuba, Karol
  id: 3FDF9472-F248-11E8-B48F-1D18A9856A87
  last_name: Kaszuba
- first_name: Gurdeep S.
  full_name: Minhas, Gurdeep S.
  last_name: Minhas
- first_name: Rozbeh
  full_name: Baradaran, Rozbeh
  last_name: Baradaran
- first_name: Margherita
  full_name: Tambalo, Margherita
  id: 4187dfe4-ec23-11ea-ae46-f08ab378313a
  last_name: Tambalo
- first_name: David T.
  full_name: Gallagher, David T.
  last_name: Gallagher
- first_name: Leonid A
  full_name: Sazanov, Leonid A
  id: 338D39FE-F248-11E8-B48F-1D18A9856A87
  last_name: Sazanov
  orcid: 0000-0002-0977-7989
citation:
  ama: Gutierrez-Fernandez J, Kaszuba K, Minhas GS, et al. Key role of quinone in
    the mechanism of respiratory complex I. <i>Nature Communications</i>. 2020;11(1).
    doi:<a href="https://doi.org/10.1038/s41467-020-17957-0">10.1038/s41467-020-17957-0</a>
  apa: Gutierrez-Fernandez, J., Kaszuba, K., Minhas, G. S., Baradaran, R., Tambalo,
    M., Gallagher, D. T., &#38; Sazanov, L. A. (2020). Key role of quinone in the
    mechanism of respiratory complex I. <i>Nature Communications</i>. Springer Nature.
    <a href="https://doi.org/10.1038/s41467-020-17957-0">https://doi.org/10.1038/s41467-020-17957-0</a>
  chicago: Gutierrez-Fernandez, Javier, Karol Kaszuba, Gurdeep S. Minhas, Rozbeh Baradaran,
    Margherita Tambalo, David T. Gallagher, and Leonid A Sazanov. “Key Role of Quinone
    in the Mechanism of Respiratory Complex I.” <i>Nature Communications</i>. Springer
    Nature, 2020. <a href="https://doi.org/10.1038/s41467-020-17957-0">https://doi.org/10.1038/s41467-020-17957-0</a>.
  ieee: J. Gutierrez-Fernandez <i>et al.</i>, “Key role of quinone in the mechanism
    of respiratory complex I,” <i>Nature Communications</i>, vol. 11, no. 1. Springer
    Nature, 2020.
  ista: Gutierrez-Fernandez J, Kaszuba K, Minhas GS, Baradaran R, Tambalo M, Gallagher
    DT, Sazanov LA. 2020. Key role of quinone in the mechanism of respiratory complex
    I. Nature Communications. 11(1), 4135.
  mla: Gutierrez-Fernandez, Javier, et al. “Key Role of Quinone in the Mechanism of
    Respiratory Complex I.” <i>Nature Communications</i>, vol. 11, no. 1, 4135, Springer
    Nature, 2020, doi:<a href="https://doi.org/10.1038/s41467-020-17957-0">10.1038/s41467-020-17957-0</a>.
  short: J. Gutierrez-Fernandez, K. Kaszuba, G.S. Minhas, R. Baradaran, M. Tambalo,
    D.T. Gallagher, L.A. Sazanov, Nature Communications 11 (2020).
date_created: 2020-08-30T22:01:10Z
date_published: 2020-08-18T00:00:00Z
date_updated: 2023-08-22T09:03:00Z
day: '18'
ddc:
- '570'
department:
- _id: LeSa
doi: 10.1038/s41467-020-17957-0
external_id:
  isi:
  - '000607072900001'
  pmid:
  - '32811817'
file:
- access_level: open_access
  checksum: 52b96f41d7d0db9728064c08da00d030
  content_type: application/pdf
  creator: cziletti
  date_created: 2020-08-31T13:40:00Z
  date_updated: 2020-08-31T13:40:00Z
  file_id: '8326'
  file_name: 2020_NatComm_Gutierrez-Fernandez.pdf
  file_size: 7527373
  relation: main_file
  success: 1
file_date_updated: 2020-08-31T13:40:00Z
has_accepted_license: '1'
intvolume: '        11'
isi: 1
issue: '1'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
pmid: 1
publication: Nature Communications
publication_identifier:
  eissn:
  - '20411723'
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
  link:
  - description: News on IST Homepage
    relation: press_release
    url: https://ist.ac.at/en/news/mystery-of-giant-proton-pump-solved/
scopus_import: '1'
status: public
title: Key role of quinone in the mechanism of respiratory complex I
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 11
year: '2020'
...
---
_id: '8319'
abstract:
- lang: eng
  text: We demonstrate that releasing atoms into free space from an optical lattice
    does not deteriorate cavity-generated spin squeezing for metrological purposes.
    In this work, an ensemble of 500000 spin-squeezed atoms in a high-finesse optical
    cavity with near-uniform atom-cavity coupling is prepared, released into free
    space, recaptured in the cavity, and probed. Up to ∼10 dB of metrologically relevant
    squeezing is retrieved for 700μs free-fall times, and decaying levels of squeezing
    are realized for up to 3 ms free-fall times. The degradation of squeezing results
    from loss of atom-cavity coupling homogeneity between the initial squeezed state
    generation and final collective state readout. A theoretical model is developed
    to quantify this degradation and this model is experimentally validated.
acknowledgement: We thank N. Engelsen for comments on the manuscript. This work was
  supported by the Office of Naval Research, Vannevar Bush Faculty Fellowship, Department
  of Energy, and Defense Threat Reduction Agency. R.K. was partly supported by the
  AQT/INQNET program at Caltech.
article_number: '012224'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Yunfan
  full_name: Wu, Yunfan
  last_name: Wu
- first_name: Rajiv
  full_name: Krishnakumar, Rajiv
  last_name: Krishnakumar
- first_name: Julián
  full_name: Martínez-Rincón, Julián
  last_name: Martínez-Rincón
- first_name: Benjamin K.
  full_name: Malia, Benjamin K.
  last_name: Malia
- first_name: Onur
  full_name: Hosten, Onur
  id: 4C02D85E-F248-11E8-B48F-1D18A9856A87
  last_name: Hosten
  orcid: 0000-0002-2031-204X
- first_name: Mark A.
  full_name: Kasevich, Mark A.
  last_name: Kasevich
citation:
  ama: Wu Y, Krishnakumar R, Martínez-Rincón J, Malia BK, Hosten O, Kasevich MA. Retrieval
    of cavity-generated atomic spin squeezing after free-space release. <i>Physical
    Review A</i>. 2020;102(1). doi:<a href="https://doi.org/10.1103/PhysRevA.102.012224">10.1103/PhysRevA.102.012224</a>
  apa: Wu, Y., Krishnakumar, R., Martínez-Rincón, J., Malia, B. K., Hosten, O., &#38;
    Kasevich, M. A. (2020). Retrieval of cavity-generated atomic spin squeezing after
    free-space release. <i>Physical Review A</i>. American Physical Society. <a href="https://doi.org/10.1103/PhysRevA.102.012224">https://doi.org/10.1103/PhysRevA.102.012224</a>
  chicago: Wu, Yunfan, Rajiv Krishnakumar, Julián Martínez-Rincón, Benjamin K. Malia,
    Onur Hosten, and Mark A. Kasevich. “Retrieval of Cavity-Generated Atomic Spin
    Squeezing after Free-Space Release.” <i>Physical Review A</i>. American Physical
    Society, 2020. <a href="https://doi.org/10.1103/PhysRevA.102.012224">https://doi.org/10.1103/PhysRevA.102.012224</a>.
  ieee: Y. Wu, R. Krishnakumar, J. Martínez-Rincón, B. K. Malia, O. Hosten, and M.
    A. Kasevich, “Retrieval of cavity-generated atomic spin squeezing after free-space
    release,” <i>Physical Review A</i>, vol. 102, no. 1. American Physical Society,
    2020.
  ista: Wu Y, Krishnakumar R, Martínez-Rincón J, Malia BK, Hosten O, Kasevich MA.
    2020. Retrieval of cavity-generated atomic spin squeezing after free-space release.
    Physical Review A. 102(1), 012224.
  mla: Wu, Yunfan, et al. “Retrieval of Cavity-Generated Atomic Spin Squeezing after
    Free-Space Release.” <i>Physical Review A</i>, vol. 102, no. 1, 012224, American
    Physical Society, 2020, doi:<a href="https://doi.org/10.1103/PhysRevA.102.012224">10.1103/PhysRevA.102.012224</a>.
  short: Y. Wu, R. Krishnakumar, J. Martínez-Rincón, B.K. Malia, O. Hosten, M.A. Kasevich,
    Physical Review A 102 (2020).
date_created: 2020-08-30T22:01:10Z
date_published: 2020-07-30T00:00:00Z
date_updated: 2024-02-28T13:11:28Z
day: '30'
department:
- _id: OnHo
doi: 10.1103/PhysRevA.102.012224
external_id:
  arxiv:
  - '1912.08334'
  isi:
  - '000555104200011'
intvolume: '       102'
isi: 1
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1912.08334
month: '07'
oa: 1
oa_version: Preprint
publication: Physical Review A
publication_identifier:
  eissn:
  - '24699934'
  issn:
  - '24699926'
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Retrieval of cavity-generated atomic spin squeezing after free-space release
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 102
year: '2020'
...
---
_id: '8320'
abstract:
- lang: eng
  text: The genetic code is considered to use five nucleic bases (adenine, guanine,
    cytosine, thymine and uracil), which form two pairs for encoding information in
    DNA and two pairs for encoding information in RNA. Nevertheless, in recent years
    several artificial base pairs have been developed in attempts to expand the genetic
    code. Employment of these additional base pairs increases the information capacity
    and variety of DNA sequences, and provides a platform for the site-specific, enzymatic
    incorporation of extra functional components into DNA and RNA. As a result, of
    the development of such expanded systems, many artificial base pairs have been
    synthesized and tested under various conditions. Following many stages of enhancement,
    unnatural base pairs have been modified to eliminate their weak points, qualifying
    them for specific research needs. Moreover, the first attempts to create a semi-synthetic
    organism containing DNA with unnatural base pairs seem to have been successful.
    This further extends the possible applications of these kinds of pairs. Herein,
    we describe the most significant qualities of unnatural base pairs and their actual
    applications.
acknowledgement: We would like to thank our co-workers and members of the Alkalaeva
  lab for participating in discussions about the topics covered in this essay.
article_processing_charge: No
article_type: original
author:
- first_name: S. A.
  full_name: Mukba, S. A.
  last_name: Mukba
- first_name: Petr
  full_name: Vlasov, Petr
  id: 38BB9AC4-F248-11E8-B48F-1D18A9856A87
  last_name: Vlasov
- first_name: P. M.
  full_name: Kolosov, P. M.
  last_name: Kolosov
- first_name: E. Y.
  full_name: Shuvalova, E. Y.
  last_name: Shuvalova
- first_name: T. V.
  full_name: Egorova, T. V.
  last_name: Egorova
- first_name: E. Z.
  full_name: Alkalaeva, E. Z.
  last_name: Alkalaeva
citation:
  ama: 'Mukba SA, Vlasov P, Kolosov PM, Shuvalova EY, Egorova TV, Alkalaeva EZ. Expanding
    the genetic code: Unnatural base pairs in biological systems. <i>Molecular Biology</i>.
    2020;54(4):475-484. doi:<a href="https://doi.org/10.1134/S0026893320040111">10.1134/S0026893320040111</a>'
  apa: 'Mukba, S. A., Vlasov, P., Kolosov, P. M., Shuvalova, E. Y., Egorova, T. V.,
    &#38; Alkalaeva, E. Z. (2020). Expanding the genetic code: Unnatural base pairs
    in biological systems. <i>Molecular Biology</i>. Springer Nature. <a href="https://doi.org/10.1134/S0026893320040111">https://doi.org/10.1134/S0026893320040111</a>'
  chicago: 'Mukba, S. A., Petr Vlasov, P. M. Kolosov, E. Y. Shuvalova, T. V. Egorova,
    and E. Z. Alkalaeva. “Expanding the Genetic Code: Unnatural Base Pairs in Biological
    Systems.” <i>Molecular Biology</i>. Springer Nature, 2020. <a href="https://doi.org/10.1134/S0026893320040111">https://doi.org/10.1134/S0026893320040111</a>.'
  ieee: 'S. A. Mukba, P. Vlasov, P. M. Kolosov, E. Y. Shuvalova, T. V. Egorova, and
    E. Z. Alkalaeva, “Expanding the genetic code: Unnatural base pairs in biological
    systems,” <i>Molecular Biology</i>, vol. 54, no. 4. Springer Nature, pp. 475–484,
    2020.'
  ista: 'Mukba SA, Vlasov P, Kolosov PM, Shuvalova EY, Egorova TV, Alkalaeva EZ. 2020.
    Expanding the genetic code: Unnatural base pairs in biological systems. Molecular
    Biology. 54(4), 475–484.'
  mla: 'Mukba, S. A., et al. “Expanding the Genetic Code: Unnatural Base Pairs in
    Biological Systems.” <i>Molecular Biology</i>, vol. 54, no. 4, Springer Nature,
    2020, pp. 475–84, doi:<a href="https://doi.org/10.1134/S0026893320040111">10.1134/S0026893320040111</a>.'
  short: S.A. Mukba, P. Vlasov, P.M. Kolosov, E.Y. Shuvalova, T.V. Egorova, E.Z. Alkalaeva,
    Molecular Biology 54 (2020) 475–484.
date_created: 2020-08-30T22:01:11Z
date_published: 2020-08-19T00:00:00Z
date_updated: 2023-08-22T09:01:03Z
day: '19'
department:
- _id: FyKo
doi: 10.1134/S0026893320040111
external_id:
  isi:
  - '000562110300001'
intvolume: '        54'
isi: 1
issue: '4'
language:
- iso: eng
month: '08'
oa_version: None
page: 475-484
publication: Molecular Biology
publication_identifier:
  eissn:
  - '16083245'
  issn:
  - '00268933'
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
  record:
  - id: '8321'
    relation: original
    status: public
scopus_import: '1'
status: public
title: 'Expanding the genetic code: Unnatural base pairs in biological systems'
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 54
year: '2020'
...
---
_id: '8321'
abstract:
- lang: eng
  text: The genetic code is considered to use five nucleic bases (adenine, guanine,
    cytosine, thymine and uracil), which form two pairs for encoding information in
    DNA and two pairs for encoding information in RNA. Nevertheless, in recent years
    several artificial base pairs have been developed in attempts to expand the genetic
    code. Employment of these additional base pairs increases the information capacity
    and variety of DNA sequences, and provides a platform for the site-specific, enzymatic
    incorporation of extra functional components into DNA and RNA. As a result, of
    the development of such expanded systems, many artificial base pairs have been
    synthesized and tested under various conditions. Following many stages of enhancement,
    unnatural base pairs have been modified to eliminate their weak points, qualifying
    them for specific research needs. Moreover, the first attempts to create a semi-synthetic
    organism containing DNA with unnatural base pairs seem to have been successful.
    This further extends the possible applications of these kinds of pairs. Herein,
    we describe the most significant qualities of unnatural base pairs and their actual
    applications.
article_processing_charge: No
article_type: original
author:
- first_name: S. A.
  full_name: Mukba, S. A.
  last_name: Mukba
- first_name: Petr
  full_name: Vlasov, Petr
  id: 38BB9AC4-F248-11E8-B48F-1D18A9856A87
  last_name: Vlasov
- first_name: P. M.
  full_name: Kolosov, P. M.
  last_name: Kolosov
- first_name: E. Y.
  full_name: Shuvalova, E. Y.
  last_name: Shuvalova
- first_name: T. V.
  full_name: Egorova, T. V.
  last_name: Egorova
- first_name: E. Z.
  full_name: Alkalaeva, E. Z.
  last_name: Alkalaeva
citation:
  ama: 'Mukba SA, Vlasov P, Kolosov PM, Shuvalova EY, Egorova TV, Alkalaeva EZ. Expanding
    the genetic code: Unnatural base pairs in biological systems. <i>Molekuliarnaia
    biologiia</i>. 2020;54(4):531-541. doi:<a href="https://doi.org/10.31857/S0026898420040126">10.31857/S0026898420040126</a>'
  apa: 'Mukba, S. A., Vlasov, P., Kolosov, P. M., Shuvalova, E. Y., Egorova, T. V.,
    &#38; Alkalaeva, E. Z. (2020). Expanding the genetic code: Unnatural base pairs
    in biological systems. <i>Molekuliarnaia biologiia</i>. Russian Academy of Sciences.
    <a href="https://doi.org/10.31857/S0026898420040126">https://doi.org/10.31857/S0026898420040126</a>'
  chicago: 'Mukba, S. A., Petr Vlasov, P. M. Kolosov, E. Y. Shuvalova, T. V. Egorova,
    and E. Z. Alkalaeva. “Expanding the genetic code: Unnatural base pairs in biological
    systems.” <i>Molekuliarnaia biologiia</i>. Russian Academy of Sciences, 2020.
    <a href="https://doi.org/10.31857/S0026898420040126">https://doi.org/10.31857/S0026898420040126</a>.'
  ieee: 'S. A. Mukba, P. Vlasov, P. M. Kolosov, E. Y. Shuvalova, T. V. Egorova, and
    E. Z. Alkalaeva, “Expanding the genetic code: Unnatural base pairs in biological
    systems,” <i>Molekuliarnaia biologiia</i>, vol. 54, no. 4. Russian Academy of
    Sciences, pp. 531–541, 2020.'
  ista: 'Mukba SA, Vlasov P, Kolosov PM, Shuvalova EY, Egorova TV, Alkalaeva EZ. 2020.
    Expanding the genetic code: Unnatural base pairs in biological systems. Molekuliarnaia
    biologiia. 54(4), 531–541.'
  mla: 'Mukba, S. A., et al. “Expanding the genetic code: Unnatural base pairs in
    biological systems.” <i>Molekuliarnaia biologiia</i>, vol. 54, no. 4, Russian
    Academy of Sciences, 2020, pp. 531–41, doi:<a href="https://doi.org/10.31857/S0026898420040126">10.31857/S0026898420040126</a>.'
  short: S.A. Mukba, P. Vlasov, P.M. Kolosov, E.Y. Shuvalova, T.V. Egorova, E.Z. Alkalaeva,
    Molekuliarnaia biologiia 54 (2020) 531–541.
date_created: 2020-08-30T22:01:11Z
date_published: 2020-07-01T00:00:00Z
date_updated: 2023-08-22T09:01:02Z
day: '01'
department:
- _id: FyKo
doi: 10.31857/S0026898420040126
external_id:
  pmid:
  - '32799218'
intvolume: '        54'
issue: '4'
language:
- iso: rus
month: '07'
oa_version: None
page: 531-541
pmid: 1
publication: Molekuliarnaia biologiia
publication_identifier:
  issn:
  - '00268984'
publication_status: published
publisher: Russian Academy of Sciences
quality_controlled: '1'
related_material:
  record:
  - id: '8320'
    relation: translation
    status: public
scopus_import: '1'
status: public
title: 'Expanding the genetic code: Unnatural base pairs in biological systems'
type: journal_article
user_id: D865714E-FA4E-11E9-B85B-F5C5E5697425
volume: 54
year: '2020'
...
---
_id: '8322'
abstract:
- lang: eng
  text: "Reverse firewalls were introduced at Eurocrypt 2015 by Miro-nov and Stephens-Davidowitz,
    as a method for protecting cryptographic protocols against attacks on the devices
    of the honest parties. In a nutshell: a reverse firewall is placed outside of
    a device and its goal is to “sanitize” the messages sent by it, in such a way
    that a malicious device cannot leak its secrets to the outside world. It is typically
    assumed that the cryptographic devices are attacked in a “functionality-preserving
    way” (i.e. informally speaking, the functionality of the protocol remains unchanged
    under this attacks). In their paper, Mironov and Stephens-Davidowitz construct
    a protocol for passively-secure two-party computations with firewalls, leaving
    extension of this result to stronger models as an open question.\r\nIn this paper,
    we address this problem by constructing a protocol for secure computation with
    firewalls that has two main advantages over the original protocol from Eurocrypt
    2015. Firstly, it is a multiparty computation protocol (i.e. it works for an arbitrary
    number n of the parties, and not just for 2). Secondly, it is secure in much stronger
    corruption settings, namely in the active corruption model. More precisely: we
    consider an adversary that can fully corrupt up to \U0001D45B−1 parties, while
    the remaining parties are corrupt in a functionality-preserving way.\r\nOur core
    techniques are: malleable commitments and malleable non-interactive zero-knowledge,
    which in particular allow us to create a novel protocol for multiparty augmented
    coin-tossing into the well with reverse firewalls (that is based on a protocol
    of Lindell from Crypto 2001)."
acknowledgement: We would like to thank the anonymous reviewers for their helpful
  comments and suggestions. The work was initiated while the first author was in IIT
  Madras, India. Part of this work was done while the author was visiting the University
  of Warsaw. This project has received funding from the European Research Council
  (ERC) under the European Union’s Horizon 2020 research and innovation programme
  (682815 - TOCNeT) and from the Foundation for Polish Science under grant TEAM/2016-1/4
  founded within the UE 2014–2020 Smart Growth Operational Program. The last author
  was supported by the Independent Research Fund Denmark project BETHE and the Concordium
  Blockchain Research Center, Aarhus University, Denmark.
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Suvradip
  full_name: Chakraborty, Suvradip
  id: B9CD0494-D033-11E9-B219-A439E6697425
  last_name: Chakraborty
- first_name: Stefan
  full_name: Dziembowski, Stefan
  last_name: Dziembowski
- first_name: Jesper Buus
  full_name: Nielsen, Jesper Buus
  last_name: Nielsen
citation:
  ama: 'Chakraborty S, Dziembowski S, Nielsen JB. Reverse firewalls for actively secure MPCs.
    In: <i>Advances in Cryptology – CRYPTO 2020</i>. Vol 12171. Springer Nature; 2020:732-762.
    doi:<a href="https://doi.org/10.1007/978-3-030-56880-1_26">10.1007/978-3-030-56880-1_26</a>'
  apa: 'Chakraborty, S., Dziembowski, S., &#38; Nielsen, J. B. (2020). Reverse firewalls for actively secure MPCs.
    In <i>Advances in Cryptology – CRYPTO 2020</i> (Vol. 12171, pp. 732–762). Santa
    Barbara, CA, United States: Springer Nature. <a href="https://doi.org/10.1007/978-3-030-56880-1_26">https://doi.org/10.1007/978-3-030-56880-1_26</a>'
  chicago: Chakraborty, Suvradip, Stefan Dziembowski, and Jesper Buus Nielsen. “Reverse Firewalls for Actively Secure MPCs.”
    In <i>Advances in Cryptology – CRYPTO 2020</i>, 12171:732–62. Springer Nature,
    2020. <a href="https://doi.org/10.1007/978-3-030-56880-1_26">https://doi.org/10.1007/978-3-030-56880-1_26</a>.
  ieee: S. Chakraborty, S. Dziembowski, and J. B. Nielsen, “Reverse firewalls for actively secure MPCs,”
    in <i>Advances in Cryptology – CRYPTO 2020</i>, Santa Barbara, CA, United States,
    2020, vol. 12171, pp. 732–762.
  ista: 'Chakraborty S, Dziembowski S, Nielsen JB. 2020. Reverse firewalls for actively secure MPCs.
    Advances in Cryptology – CRYPTO 2020. CRYPTO: Annual International Cryptology
    Conference, LNCS, vol. 12171, 732–762.'
  mla: Chakraborty, Suvradip, et al. “Reverse Firewalls for Actively Secure MPCs.”
    <i>Advances in Cryptology – CRYPTO 2020</i>, vol. 12171, Springer Nature, 2020,
    pp. 732–62, doi:<a href="https://doi.org/10.1007/978-3-030-56880-1_26">10.1007/978-3-030-56880-1_26</a>.
  short: S. Chakraborty, S. Dziembowski, J.B. Nielsen, in:, Advances in Cryptology
    – CRYPTO 2020, Springer Nature, 2020, pp. 732–762.
conference:
  end_date: 2020-08-21
  location: Santa Barbara, CA, United States
  name: 'CRYPTO: Annual International Cryptology Conference'
  start_date: 2020-08-17
date_created: 2020-08-30T22:01:12Z
date_published: 2020-08-10T00:00:00Z
date_updated: 2021-01-12T08:18:08Z
day: '10'
department:
- _id: KrPi
doi: 10.1007/978-3-030-56880-1_26
ec_funded: 1
intvolume: '     12171'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://eprint.iacr.org/2019/1317
month: '08'
oa: 1
oa_version: Preprint
page: 732-762
project:
- _id: 258AA5B2-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '682815'
  name: Teaching Old Crypto New Tricks
publication: Advances in Cryptology – CRYPTO 2020
publication_identifier:
  eissn:
  - '16113349'
  isbn:
  - '9783030568795'
  issn:
  - '03029743'
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Reverse firewalls for actively secure MPCs
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 12171
year: '2020'
...
---
_id: '8323'
article_processing_charge: No
article_type: letter_note
author:
- first_name: János
  full_name: Pach, János
  id: E62E3130-B088-11EA-B919-BF823C25FEA4
  last_name: Pach
citation:
  ama: Pach J. A farewell to Ricky Pollack. <i>Discrete and Computational Geometry</i>.
    2020;64:571-574. doi:<a href="https://doi.org/10.1007/s00454-020-00237-5">10.1007/s00454-020-00237-5</a>
  apa: Pach, J. (2020). A farewell to Ricky Pollack. <i>Discrete and Computational
    Geometry</i>. Springer Nature. <a href="https://doi.org/10.1007/s00454-020-00237-5">https://doi.org/10.1007/s00454-020-00237-5</a>
  chicago: Pach, János. “A Farewell to Ricky Pollack.” <i>Discrete and Computational
    Geometry</i>. Springer Nature, 2020. <a href="https://doi.org/10.1007/s00454-020-00237-5">https://doi.org/10.1007/s00454-020-00237-5</a>.
  ieee: J. Pach, “A farewell to Ricky Pollack,” <i>Discrete and Computational Geometry</i>,
    vol. 64. Springer Nature, pp. 571–574, 2020.
  ista: Pach J. 2020. A farewell to Ricky Pollack. Discrete and Computational Geometry.
    64, 571–574.
  mla: Pach, János. “A Farewell to Ricky Pollack.” <i>Discrete and Computational Geometry</i>,
    vol. 64, Springer Nature, 2020, pp. 571–74, doi:<a href="https://doi.org/10.1007/s00454-020-00237-5">10.1007/s00454-020-00237-5</a>.
  short: J. Pach, Discrete and Computational Geometry 64 (2020) 571–574.
date_created: 2020-08-30T22:01:12Z
date_published: 2020-10-01T00:00:00Z
date_updated: 2023-08-22T09:05:04Z
day: '01'
department:
- _id: HeEd
doi: 10.1007/s00454-020-00237-5
external_id:
  isi:
  - '000561483500001'
intvolume: '        64'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1007/s00454-020-00237-5
month: '10'
oa: 1
oa_version: None
page: 571-574
publication: Discrete and Computational Geometry
publication_identifier:
  eissn:
  - '14320444'
  issn:
  - '01795376'
publication_status: published
publisher: Springer Nature
scopus_import: '1'
status: public
title: A farewell to Ricky Pollack
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 64
year: '2020'
...
---
_id: '8324'
abstract:
- lang: eng
  text: The notion of program sensitivity (aka Lipschitz continuity) specifies that
    changes in the program input result in proportional changes to the program output.
    For probabilistic programs the notion is naturally extended to expected sensitivity.
    A previous approach develops a relational program logic framework for proving
    expected sensitivity of probabilistic while loops, where the number of iterations
    is fixed and bounded. In this work, we consider probabilistic while loops where
    the number of iterations is not fixed, but randomized and depends on the initial
    input values. We present a sound approach for proving expected sensitivity of
    such programs. Our sound approach is martingale-based and can be automated through
    existing martingale-synthesis algorithms. Furthermore, our approach is compositional
    for sequential composition of while loops under a mild side condition. We demonstrate
    the effectiveness of our approach on several classical examples from Gambler's
    Ruin, stochastic hybrid systems and stochastic gradient descent. We also present
    experimental results showing that our automated approach can handle various probabilistic
    programs in the literature.
acknowledgement: We thank anonymous reviewers for helpful comments, especially for
  pointing to us a scenario of piecewise-linear approximation (Remark5). The research
  was partially supported by the National Natural Science Foundation of China (NSFC)
  under Grant No. 61802254, 61672229, 61832015,61772336,11871221 and Austrian Science
  Fund (FWF) NFN under Grant No. S11407-N23 (RiSE/SHiNE). We thank Prof. Yuxi Fu,
  director of the BASICS Lab at Shanghai Jiao Tong University, for his support.
article_number: '25'
article_processing_charge: No
arxiv: 1
author:
- first_name: Peixin
  full_name: Wang, Peixin
  last_name: Wang
- first_name: Hongfei
  full_name: Fu, Hongfei
  last_name: Fu
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Yuxin
  full_name: Deng, Yuxin
  last_name: Deng
- first_name: Ming
  full_name: Xu, Ming
  last_name: Xu
citation:
  ama: 'Wang P, Fu H, Chatterjee K, Deng Y, Xu M. Proving expected sensitivity of
    probabilistic programs with randomized variable-dependent termination time. In:
    <i>Proceedings of the ACM on Programming Languages</i>. Vol 4. ACM; 2020. doi:<a
    href="https://doi.org/10.1145/3371093">10.1145/3371093</a>'
  apa: Wang, P., Fu, H., Chatterjee, K., Deng, Y., &#38; Xu, M. (2020). Proving expected
    sensitivity of probabilistic programs with randomized variable-dependent termination
    time. In <i>Proceedings of the ACM on Programming Languages</i> (Vol. 4). ACM.
    <a href="https://doi.org/10.1145/3371093">https://doi.org/10.1145/3371093</a>
  chicago: Wang, Peixin, Hongfei Fu, Krishnendu Chatterjee, Yuxin Deng, and Ming Xu.
    “Proving Expected Sensitivity of Probabilistic Programs with Randomized Variable-Dependent
    Termination Time.” In <i>Proceedings of the ACM on Programming Languages</i>,
    Vol. 4. ACM, 2020. <a href="https://doi.org/10.1145/3371093">https://doi.org/10.1145/3371093</a>.
  ieee: P. Wang, H. Fu, K. Chatterjee, Y. Deng, and M. Xu, “Proving expected sensitivity
    of probabilistic programs with randomized variable-dependent termination time,”
    in <i>Proceedings of the ACM on Programming Languages</i>, 2020, vol. 4, no. POPL.
  ista: Wang P, Fu H, Chatterjee K, Deng Y, Xu M. 2020. Proving expected sensitivity
    of probabilistic programs with randomized variable-dependent termination time.
    Proceedings of the ACM on Programming Languages. vol. 4, 25.
  mla: Wang, Peixin, et al. “Proving Expected Sensitivity of Probabilistic Programs
    with Randomized Variable-Dependent Termination Time.” <i>Proceedings of the ACM
    on Programming Languages</i>, vol. 4, no. POPL, 25, ACM, 2020, doi:<a href="https://doi.org/10.1145/3371093">10.1145/3371093</a>.
  short: P. Wang, H. Fu, K. Chatterjee, Y. Deng, M. Xu, in:, Proceedings of the ACM
    on Programming Languages, ACM, 2020.
date_created: 2020-08-30T22:01:12Z
date_published: 2020-01-01T00:00:00Z
date_updated: 2024-02-22T15:16:45Z
day: '01'
ddc:
- '004'
department:
- _id: KrCh
doi: 10.1145/3371093
external_id:
  arxiv:
  - '1902.04744'
file:
- access_level: open_access
  checksum: c6193d109ff4ecb17e7a6513d8eb34c0
  content_type: application/pdf
  creator: cziletti
  date_created: 2020-09-01T11:12:58Z
  date_updated: 2020-09-01T11:12:58Z
  file_id: '8328'
  file_name: 2019_ACM_POPL_Wang.pdf
  file_size: 564151
  relation: main_file
  success: 1
file_date_updated: 2020-09-01T11:12:58Z
has_accepted_license: '1'
intvolume: '         4'
issue: POPL
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
project:
- _id: 25863FF4-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: S11407
  name: Game Theory
publication: Proceedings of the ACM on Programming Languages
publication_identifier:
  eissn:
  - 2475-1421
publication_status: published
publisher: ACM
quality_controlled: '1'
related_material:
  link:
  - relation: software
    url: https://doi.org/10.5281/zenodo.3533633
scopus_import: '1'
status: public
title: Proving expected sensitivity of probabilistic programs with randomized variable-dependent
  termination time
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: conference
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 4
year: '2020'
...
---
_id: '8325'
abstract:
- lang: eng
  text: "Let \U0001D439:ℤ2→ℤ be the pointwise minimum of several linear functions.
    The theory of smoothing allows us to prove that under certain conditions there
    exists the pointwise minimal function among all integer-valued superharmonic functions
    coinciding with F “at infinity”. We develop such a theory to prove existence of
    so-called solitons (or strings) in a sandpile model, studied by S. Caracciolo,
    G. Paoletti, and A. Sportiello. Thus we made a step towards understanding the
    phenomena of the identity in the sandpile group for planar domains where solitons
    appear according to experiments. We prove that sandpile states, defined using
    our smoothing procedure, move changeless when we apply the wave operator (that
    is why we call them solitons), and can interact, forming triads and nodes. "
acknowledgement: We thank Andrea Sportiello for sharing his insights on perturbative
  regimes of the Abelian sandpile model which was the starting point of our work.
  We also thank Grigory Mikhalkin, who encouraged us to approach this problem. We
  thank an anonymous referee. Also we thank Misha Khristoforov and Sergey Lanzat who
  participated on the initial state of this project, when we had nothing except the
  computer simulation and pictures. We thank Mikhail Raskin for providing us the code
  on Golly for faster simulations. Ilia Zharkov, Ilia Itenberg, Kristin Shaw, Max
  Karev, Lionel Levine, Ernesto Lupercio, Pavol Ševera, Yulieth Prieto, Michael Polyak,
  Danila Cherkashin asked us a lot of questions and listened to us; not all of their
  questions found answers here, but we are going to treat them in subsequent papers.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Nikita
  full_name: Kalinin, Nikita
  last_name: Kalinin
- first_name: Mikhail
  full_name: Shkolnikov, Mikhail
  id: 35084A62-F248-11E8-B48F-1D18A9856A87
  last_name: Shkolnikov
  orcid: 0000-0002-4310-178X
citation:
  ama: Kalinin N, Shkolnikov M. Sandpile solitons via smoothing of superharmonic functions.
    <i>Communications in Mathematical Physics</i>. 2020;378(9):1649-1675. doi:<a href="https://doi.org/10.1007/s00220-020-03828-8">10.1007/s00220-020-03828-8</a>
  apa: Kalinin, N., &#38; Shkolnikov, M. (2020). Sandpile solitons via smoothing of
    superharmonic functions. <i>Communications in Mathematical Physics</i>. Springer
    Nature. <a href="https://doi.org/10.1007/s00220-020-03828-8">https://doi.org/10.1007/s00220-020-03828-8</a>
  chicago: Kalinin, Nikita, and Mikhail Shkolnikov. “Sandpile Solitons via Smoothing
    of Superharmonic Functions.” <i>Communications in Mathematical Physics</i>. Springer
    Nature, 2020. <a href="https://doi.org/10.1007/s00220-020-03828-8">https://doi.org/10.1007/s00220-020-03828-8</a>.
  ieee: N. Kalinin and M. Shkolnikov, “Sandpile solitons via smoothing of superharmonic
    functions,” <i>Communications in Mathematical Physics</i>, vol. 378, no. 9. Springer
    Nature, pp. 1649–1675, 2020.
  ista: Kalinin N, Shkolnikov M. 2020. Sandpile solitons via smoothing of superharmonic
    functions. Communications in Mathematical Physics. 378(9), 1649–1675.
  mla: Kalinin, Nikita, and Mikhail Shkolnikov. “Sandpile Solitons via Smoothing of
    Superharmonic Functions.” <i>Communications in Mathematical Physics</i>, vol.
    378, no. 9, Springer Nature, 2020, pp. 1649–75, doi:<a href="https://doi.org/10.1007/s00220-020-03828-8">10.1007/s00220-020-03828-8</a>.
  short: N. Kalinin, M. Shkolnikov, Communications in Mathematical Physics 378 (2020)
    1649–1675.
date_created: 2020-08-30T22:01:13Z
date_published: 2020-09-01T00:00:00Z
date_updated: 2023-08-22T09:00:03Z
day: '01'
department:
- _id: TaHa
doi: 10.1007/s00220-020-03828-8
ec_funded: 1
external_id:
  arxiv:
  - '1711.04285'
  isi:
  - '000560620600001'
intvolume: '       378'
isi: 1
issue: '9'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1711.04285
month: '09'
oa: 1
oa_version: Preprint
page: 1649-1675
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '291734'
  name: International IST Postdoc Fellowship Programme
publication: Communications in Mathematical Physics
publication_identifier:
  eissn:
  - '14320916'
  issn:
  - '00103616'
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Sandpile solitons via smoothing of superharmonic functions
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 378
year: '2020'
...
---
_id: '8329'
abstract:
- lang: eng
  text: We show the synthesis of a redox‐active quinone, 2‐methoxy‐1,4‐hydroquinone
    (MHQ), from a bio‐based feedstock and its suitability as electrolyte in aqueous
    redox flow batteries. We identified semiquinone intermediates at insufficiently
    low pH and quinoid radicals as responsible for decomposition of MHQ under electrochemical
    conditions. Both can be avoided and/or stabilized, respectively, using H 3 PO
    4 electrolyte, allowing for reversible cycling in a redox flow battery for hundreds
    of cycles.
acknowledgement: The Austrian Research Promotion Agency (FFG) is gratefully acknowledged
  for financial support of the project LignoBatt (860429).
article_processing_charge: No
article_type: original
author:
- first_name: Werner
  full_name: Schlemmer, Werner
  last_name: Schlemmer
- first_name: Philipp
  full_name: Nothdurft, Philipp
  last_name: Nothdurft
- first_name: Alina
  full_name: Petzold, Alina
  last_name: Petzold
- first_name: Philipp
  full_name: Frühwirt, Philipp
  last_name: Frühwirt
- first_name: Max
  full_name: Schmallegger, Max
  last_name: Schmallegger
- first_name: Georg
  full_name: Gescheidt-Demner, Georg
  last_name: Gescheidt-Demner
- first_name: Roland
  full_name: Fischer, Roland
  last_name: Fischer
- first_name: Stefan Alexander
  full_name: Freunberger, Stefan Alexander
  id: A8CA28E6-CE23-11E9-AD2D-EC27E6697425
  last_name: Freunberger
  orcid: 0000-0003-2902-5319
- first_name: Wolfgang
  full_name: Kern, Wolfgang
  last_name: Kern
- first_name: Stefan
  full_name: Spirk, Stefan
  last_name: Spirk
citation:
  ama: Schlemmer W, Nothdurft P, Petzold A, et al. 2‐methoxyhydroquinone from vanillin
    for aqueous redox‐flow batteries. <i>Angewandte Chemie International Edition</i>.
    2020;59(51):22943-22946. doi:<a href="https://doi.org/10.1002/anie.202008253">10.1002/anie.202008253</a>
  apa: Schlemmer, W., Nothdurft, P., Petzold, A., Frühwirt, P., Schmallegger, M.,
    Gescheidt-Demner, G., … Spirk, S. (2020). 2‐methoxyhydroquinone from vanillin
    for aqueous redox‐flow batteries. <i>Angewandte Chemie International Edition</i>.
    Wiley. <a href="https://doi.org/10.1002/anie.202008253">https://doi.org/10.1002/anie.202008253</a>
  chicago: Schlemmer, Werner, Philipp Nothdurft, Alina Petzold, Philipp Frühwirt,
    Max Schmallegger, Georg Gescheidt-Demner, Roland Fischer, Stefan Alexander Freunberger,
    Wolfgang Kern, and Stefan Spirk. “2‐methoxyhydroquinone from Vanillin for Aqueous
    Redox‐flow Batteries.” <i>Angewandte Chemie International Edition</i>. Wiley,
    2020. <a href="https://doi.org/10.1002/anie.202008253">https://doi.org/10.1002/anie.202008253</a>.
  ieee: W. Schlemmer <i>et al.</i>, “2‐methoxyhydroquinone from vanillin for aqueous
    redox‐flow batteries,” <i>Angewandte Chemie International Edition</i>, vol. 59,
    no. 51. Wiley, pp. 22943–22946, 2020.
  ista: Schlemmer W, Nothdurft P, Petzold A, Frühwirt P, Schmallegger M, Gescheidt-Demner
    G, Fischer R, Freunberger SA, Kern W, Spirk S. 2020. 2‐methoxyhydroquinone from
    vanillin for aqueous redox‐flow batteries. Angewandte Chemie International Edition.
    59(51), 22943–22946.
  mla: Schlemmer, Werner, et al. “2‐methoxyhydroquinone from Vanillin for Aqueous
    Redox‐flow Batteries.” <i>Angewandte Chemie International Edition</i>, vol. 59,
    no. 51, Wiley, 2020, pp. 22943–46, doi:<a href="https://doi.org/10.1002/anie.202008253">10.1002/anie.202008253</a>.
  short: W. Schlemmer, P. Nothdurft, A. Petzold, P. Frühwirt, M. Schmallegger, G.
    Gescheidt-Demner, R. Fischer, S.A. Freunberger, W. Kern, S. Spirk, Angewandte
    Chemie International Edition 59 (2020) 22943–22946.
date_created: 2020-09-03T16:10:56Z
date_published: 2020-12-14T00:00:00Z
date_updated: 2023-09-05T16:03:47Z
day: '14'
department:
- _id: StFr
doi: 10.1002/anie.202008253
external_id:
  isi:
  - '000576148700001'
intvolume: '        59'
isi: 1
issue: '51'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1002/anie.202008253
month: '12'
oa: 1
oa_version: Published Version
page: 22943-22946
publication: Angewandte Chemie International Edition
publication_identifier:
  eissn:
  - 1521-3773
  issn:
  - 1433-7851
publication_status: published
publisher: Wiley
quality_controlled: '1'
related_material:
  record:
  - id: '9780'
    relation: research_data
    status: public
scopus_import: '1'
status: public
title: 2‐methoxyhydroquinone from vanillin for aqueous redox‐flow batteries
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 59
year: '2020'
...
---
_id: '8332'
abstract:
- lang: eng
  text: "Designing and verifying concurrent programs is a notoriously challenging,
    time consuming, and error prone task, even for experts. This is due to the sheer
    number of possible interleavings of a concurrent program, all of which have to
    be tracked and accounted for in a formal proof. Inventing an inductive invariant
    that captures all interleavings of a low-level implementation is theoretically
    possible, but practically intractable. We develop a refinement-based verification
    framework that provides mechanisms to simplify proof construction by decomposing
    the verification task into smaller subtasks.\r\n\r\nIn a first line of work, we
    present a foundation for refinement reasoning over structured concurrent programs.
    We introduce layered concurrent programs as a compact notation to represent multi-layer
    refinement proofs. A layered concurrent program specifies a sequence of connected
    concurrent programs, from most concrete to most abstract, such that common parts
    of different programs are written exactly once. Each program in this sequence
    is expressed as structured concurrent program, i.e., a program over (potentially
    recursive) procedures, imperative control flow, gated atomic actions, structured
    parallelism, and asynchronous concurrency. This is in contrast to existing refinement-based
    verifiers, which represent concurrent systems as flat transition relations. We
    present a powerful refinement proof rule that decomposes refinement checking over
    structured programs into modular verification conditions. Refinement checking
    is supported by a new form of modular, parameterized invariants, called yield
    invariants, and a linear permission system to enhance local reasoning.\r\n\r\nIn
    a second line of work, we present two new reduction-based program transformations
    that target asynchronous programs. These transformations reduce the number of
    interleavings that need to be considered, thus reducing the complexity of invariants.
    Synchronization simplifies the verification of asynchronous programs by introducing
    the fiction, for proof purposes, that asynchronous operations complete synchronously.
    Synchronization summarizes an asynchronous computation as immediate atomic effect.
    Inductive sequentialization establishes sequential reductions that captures every
    behavior of the original program up to reordering of coarse-grained commutative
    actions. A sequential reduction of a concurrent program is easy to reason about
    since it corresponds to a simple execution of the program in an idealized synchronous
    environment, where processes act in a fixed order and at the same speed.\r\n\r\nOur
    approach is implemented the CIVL verifier, which has been successfully used for
    the verification of several complex concurrent programs. In our methodology, the
    overall correctness of a program is established piecemeal by focusing on the invariant
    required for each refinement step separately. While the programmer does the creative
    work of specifying the chain of programs and the inductive invariant justifying
    each link in the chain, the tool automatically constructs the verification conditions
    underlying each refinement step."
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Bernhard
  full_name: Kragl, Bernhard
  id: 320FC952-F248-11E8-B48F-1D18A9856A87
  last_name: Kragl
  orcid: 0000-0001-7745-9117
citation:
  ama: 'Kragl B. Verifying concurrent programs: Refinement, synchronization, sequentialization.
    2020. doi:<a href="https://doi.org/10.15479/AT:ISTA:8332">10.15479/AT:ISTA:8332</a>'
  apa: 'Kragl, B. (2020). <i>Verifying concurrent programs: Refinement, synchronization,
    sequentialization</i>. Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/AT:ISTA:8332">https://doi.org/10.15479/AT:ISTA:8332</a>'
  chicago: 'Kragl, Bernhard. “Verifying Concurrent Programs: Refinement, Synchronization,
    Sequentialization.” Institute of Science and Technology Austria, 2020. <a href="https://doi.org/10.15479/AT:ISTA:8332">https://doi.org/10.15479/AT:ISTA:8332</a>.'
  ieee: 'B. Kragl, “Verifying concurrent programs: Refinement, synchronization, sequentialization,”
    Institute of Science and Technology Austria, 2020.'
  ista: 'Kragl B. 2020. Verifying concurrent programs: Refinement, synchronization,
    sequentialization. Institute of Science and Technology Austria.'
  mla: 'Kragl, Bernhard. <i>Verifying Concurrent Programs: Refinement, Synchronization,
    Sequentialization</i>. Institute of Science and Technology Austria, 2020, doi:<a
    href="https://doi.org/10.15479/AT:ISTA:8332">10.15479/AT:ISTA:8332</a>.'
  short: 'B. Kragl, Verifying Concurrent Programs: Refinement, Synchronization, Sequentialization,
    Institute of Science and Technology Austria, 2020.'
date_created: 2020-09-04T12:24:12Z
date_published: 2020-09-03T00:00:00Z
date_updated: 2023-09-13T08:45:08Z
day: '03'
ddc:
- '000'
degree_awarded: PhD
department:
- _id: ToHe
doi: 10.15479/AT:ISTA:8332
file:
- access_level: open_access
  checksum: 26fe261550f691280bda4c454bf015c7
  content_type: application/pdf
  creator: bkragl
  date_created: 2020-09-04T12:17:47Z
  date_updated: 2020-09-04T12:17:47Z
  file_id: '8333'
  file_name: kragl-thesis.pdf
  file_size: 1348815
  relation: main_file
- access_level: closed
  checksum: b9694ce092b7c55557122adba8337ebc
  content_type: application/zip
  creator: bkragl
  date_created: 2020-09-04T13:00:17Z
  date_updated: 2020-09-04T13:00:17Z
  file_id: '8335'
  file_name: kragl-thesis.zip
  file_size: 372312
  relation: source_file
file_date_updated: 2020-09-04T13:00:17Z
has_accepted_license: '1'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
page: '120'
publication_identifier:
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '133'
    relation: part_of_dissertation
    status: public
  - id: '8012'
    relation: part_of_dissertation
    status: public
  - id: '8195'
    relation: part_of_dissertation
    status: public
  - id: '160'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000-0002-2985-7724
title: 'Verifying concurrent programs: Refinement, synchronization, sequentialization'
type: dissertation
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2020'
...
---
_id: '8336'
abstract:
- lang: eng
  text: Plant hormone cytokinins are perceived by a subfamily of sensor histidine
    kinases (HKs), which via a two-component phosphorelay cascade activate transcriptional
    responses in the nucleus. Subcellular localization of the receptors proposed the
    endoplasmic reticulum (ER) membrane as a principal cytokinin perception site,
    while study of cytokinin transport pointed to the plasma membrane (PM)-mediated
    cytokinin signalling. Here, by detailed monitoring of subcellular localizations
    of the fluorescently labelled natural cytokinin probe and the receptor ARABIDOPSIS
    HISTIDINE KINASE 4 (CRE1/AHK4) fused to GFP reporter, we show that pools of the
    ER-located cytokinin receptors can enter the secretory pathway and reach the PM
    in cells of the root apical meristem, and the cell plate of dividing meristematic
    cells. Brefeldin A (BFA) experiments revealed vesicular recycling of the receptor
    and its accumulation in BFA compartments. We provide a revised view on cytokinin
    signalling and the possibility of multiple sites of perception at PM and ER.
acknowledged_ssus:
- _id: Bio
- _id: LifeSc
acknowledgement: This paper is dedicated to deceased P. Galuszka for his support and
  contribution to the project. This research was supported by the Scientific Service
  Units (SSU) of IST-Austria through resources provided by the Bioimaging Facility
  (BIF), the Life Science Facility (LSF) and by Centre of the Region Haná (CRH), Palacký
  University. We thank Lucia Hlusková, Zuzana Pěkná and Martin Hönig for technical
  assistance, and Fernando Aniento, Rashed Abualia and Andrej Hurný for sharing material.
  The work was supported from ERDF project “Plants as a tool for sustainable global
  development” (No. CZ.02.1.01/0.0/0.0/16_019/0000827), from Czech Science Foundation
  via projects 16-04184S (O.P., K.K. and K.D.), 18-23972Y (D.Z., K.K.), 17-21122S
  (K.B.), Erasmus+ (K.K.), Endowment Fund of Palacký University (K.K.) and EMBO Long-Term
  Fellowship, ALTF number 710-2016 (J.C.M.); People Programme (Marie Curie Actions)
  of the European Union’s Seventh Framework Programme (FP7/2007-2013) under REA grant
  agreement no. [291734] (N.C.); DOC Fellowship of the Austrian Academy of Sciences
  at the Institute of Science and Technology, Austria (H.S.).
article_number: '4285'
article_processing_charge: No
article_type: original
author:
- first_name: Karolina
  full_name: Kubiasova, Karolina
  id: 946011F4-3E71-11EA-860B-C7A73DDC885E
  last_name: Kubiasova
  orcid: 0000-0001-5630-9419
- first_name: Juan C
  full_name: Montesinos López, Juan C
  id: 310A8E3E-F248-11E8-B48F-1D18A9856A87
  last_name: Montesinos López
  orcid: 0000-0001-9179-6099
- first_name: Olga
  full_name: Šamajová, Olga
  last_name: Šamajová
- first_name: Jaroslav
  full_name: Nisler, Jaroslav
  last_name: Nisler
- first_name: Václav
  full_name: Mik, Václav
  last_name: Mik
- first_name: Hana
  full_name: Semeradova, Hana
  id: 42FE702E-F248-11E8-B48F-1D18A9856A87
  last_name: Semeradova
- first_name: Lucie
  full_name: Plíhalová, Lucie
  last_name: Plíhalová
- first_name: Ondřej
  full_name: Novák, Ondřej
  last_name: Novák
- first_name: Peter
  full_name: Marhavý, Peter
  id: 3F45B078-F248-11E8-B48F-1D18A9856A87
  last_name: Marhavý
  orcid: 0000-0001-5227-5741
- first_name: Nicola
  full_name: Cavallari, Nicola
  id: 457160E6-F248-11E8-B48F-1D18A9856A87
  last_name: Cavallari
- first_name: David
  full_name: Zalabák, David
  last_name: Zalabák
- first_name: Karel
  full_name: Berka, Karel
  last_name: Berka
- first_name: Karel
  full_name: Doležal, Karel
  last_name: Doležal
- first_name: Petr
  full_name: Galuszka, Petr
  last_name: Galuszka
- first_name: Jozef
  full_name: Šamaj, Jozef
  last_name: Šamaj
- first_name: Miroslav
  full_name: Strnad, Miroslav
  last_name: Strnad
- first_name: Eva
  full_name: Benková, Eva
  id: 38F4F166-F248-11E8-B48F-1D18A9856A87
  last_name: Benková
  orcid: 0000-0002-8510-9739
- first_name: Ondřej
  full_name: Plíhal, Ondřej
  last_name: Plíhal
- first_name: Lukáš
  full_name: Spíchal, Lukáš
  last_name: Spíchal
citation:
  ama: Kubiasova K, Montesinos López JC, Šamajová O, et al. Cytokinin fluoroprobe
    reveals multiple sites of cytokinin perception at plasma membrane and endoplasmic
    reticulum. <i>Nature Communications</i>. 2020;11. doi:<a href="https://doi.org/10.1038/s41467-020-17949-0">10.1038/s41467-020-17949-0</a>
  apa: Kubiasova, K., Montesinos López, J. C., Šamajová, O., Nisler, J., Mik, V.,
    Semerádová, H., … Spíchal, L. (2020). Cytokinin fluoroprobe reveals multiple sites
    of cytokinin perception at plasma membrane and endoplasmic reticulum. <i>Nature
    Communications</i>. Springer Nature. <a href="https://doi.org/10.1038/s41467-020-17949-0">https://doi.org/10.1038/s41467-020-17949-0</a>
  chicago: Kubiasova, Karolina, Juan C Montesinos López, Olga Šamajová, Jaroslav Nisler,
    Václav Mik, Hana Semerádová, Lucie Plíhalová, et al. “Cytokinin Fluoroprobe Reveals
    Multiple Sites of Cytokinin Perception at Plasma Membrane and Endoplasmic Reticulum.”
    <i>Nature Communications</i>. Springer Nature, 2020. <a href="https://doi.org/10.1038/s41467-020-17949-0">https://doi.org/10.1038/s41467-020-17949-0</a>.
  ieee: K. Kubiasova <i>et al.</i>, “Cytokinin fluoroprobe reveals multiple sites
    of cytokinin perception at plasma membrane and endoplasmic reticulum,” <i>Nature
    Communications</i>, vol. 11. Springer Nature, 2020.
  ista: Kubiasova K, Montesinos López JC, Šamajová O, Nisler J, Mik V, Semerádová
    H, Plíhalová L, Novák O, Marhavý P, Cavallari N, Zalabák D, Berka K, Doležal K,
    Galuszka P, Šamaj J, Strnad M, Benková E, Plíhal O, Spíchal L. 2020. Cytokinin
    fluoroprobe reveals multiple sites of cytokinin perception at plasma membrane
    and endoplasmic reticulum. Nature Communications. 11, 4285.
  mla: Kubiasova, Karolina, et al. “Cytokinin Fluoroprobe Reveals Multiple Sites of
    Cytokinin Perception at Plasma Membrane and Endoplasmic Reticulum.” <i>Nature
    Communications</i>, vol. 11, 4285, Springer Nature, 2020, doi:<a href="https://doi.org/10.1038/s41467-020-17949-0">10.1038/s41467-020-17949-0</a>.
  short: K. Kubiasova, J.C. Montesinos López, O. Šamajová, J. Nisler, V. Mik, H. Semerádová,
    L. Plíhalová, O. Novák, P. Marhavý, N. Cavallari, D. Zalabák, K. Berka, K. Doležal,
    P. Galuszka, J. Šamaj, M. Strnad, E. Benková, O. Plíhal, L. Spíchal, Nature Communications
    11 (2020).
date_created: 2020-09-06T22:01:12Z
date_published: 2020-08-27T00:00:00Z
date_updated: 2023-08-22T09:09:06Z
day: '27'
ddc:
- '580'
department:
- _id: EvBe
doi: 10.1038/s41467-020-17949-0
ec_funded: 1
external_id:
  isi:
  - '000567931000002'
  pmid:
  - '32855390'
file:
- access_level: open_access
  checksum: 7494b7665b3d2bf2d8edb13e4f12b92d
  content_type: application/pdf
  creator: dernst
  date_created: 2020-09-10T08:05:19Z
  date_updated: 2020-09-10T08:05:19Z
  file_id: '8357'
  file_name: 2020_NatureComm_Kubiasova.pdf
  file_size: 3455704
  relation: main_file
  success: 1
file_date_updated: 2020-09-10T08:05:19Z
has_accepted_license: '1'
intvolume: '        11'
isi: 1
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '291734'
  name: International IST Postdoc Fellowship Programme
- _id: 261821BC-B435-11E9-9278-68D0E5697425
  grant_number: '24746'
  name: Molecular mechanisms of the cytokinin regulated endomembrane trafficking to
    coordinate plant organogenesis.
- _id: 253E54C8-B435-11E9-9278-68D0E5697425
  grant_number: ALTF710-2016
  name: Molecular mechanism of auxindriven formative divisions delineating lateral
    root organogenesis in plants
publication: Nature Communications
publication_identifier:
  eissn:
  - '20411723'
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Cytokinin fluoroprobe reveals multiple sites of cytokinin perception at plasma
  membrane and endoplasmic reticulum
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 11
year: '2020'
...
