---
_id: '9439'
abstract:
- lang: eng
text: The ability to adapt to changes in stimulus statistics is a hallmark of sensory
systems. Here, we developed a theoretical framework that can account for the dynamics
of adaptation from an information processing perspective. We use this framework
to optimize and analyze adaptive sensory codes, and we show that codes optimized
for stationary environments can suffer from prolonged periods of poor performance
when the environment changes. To mitigate the adversarial effects of these environmental
changes, sensory systems must navigate tradeoffs between the ability to accurately
encode incoming stimuli and the ability to rapidly detect and adapt to changes
in the distribution of these stimuli. We derive families of codes that balance
these objectives, and we demonstrate their close match to experimentally observed
neural dynamics during mean and variance adaptation. Our results provide a unifying
perspective on adaptation across a range of sensory systems, environments, and
sensory tasks.
acknowledgement: We thank D. Kastner and T. Münch for generously providing figures
from their work. We also thank V. Jayaraman, M. Noorman, T. Ma, and K. Krishnamurthy
for useful discussions and feedback on the manuscript. W.F.M. was funded by the
European Union’s Horizon 2020 Research and Innovation Programme under Marie Skłodowska-Curie
Grant Agreement No. 754411. A.M.H. was supported by the Howard Hughes Medical Institute.
article_processing_charge: No
article_type: original
author:
- first_name: Wiktor F
full_name: Mlynarski, Wiktor F
id: 358A453A-F248-11E8-B48F-1D18A9856A87
last_name: Mlynarski
- first_name: Ann M.
full_name: Hermundstad, Ann M.
last_name: Hermundstad
citation:
ama: Mlynarski WF, Hermundstad AM. Efficient and adaptive sensory codes. Nature
Neuroscience. 2021;24:998-1009. doi:10.1038/s41593-021-00846-0
apa: Mlynarski, W. F., & Hermundstad, A. M. (2021). Efficient and adaptive sensory
codes. Nature Neuroscience. Springer Nature. https://doi.org/10.1038/s41593-021-00846-0
chicago: Mlynarski, Wiktor F, and Ann M. Hermundstad. “Efficient and Adaptive Sensory
Codes.” Nature Neuroscience. Springer Nature, 2021. https://doi.org/10.1038/s41593-021-00846-0.
ieee: W. F. Mlynarski and A. M. Hermundstad, “Efficient and adaptive sensory codes,”
Nature Neuroscience, vol. 24. Springer Nature, pp. 998–1009, 2021.
ista: Mlynarski WF, Hermundstad AM. 2021. Efficient and adaptive sensory codes.
Nature Neuroscience. 24, 998–1009.
mla: Mlynarski, Wiktor F., and Ann M. Hermundstad. “Efficient and Adaptive Sensory
Codes.” Nature Neuroscience, vol. 24, Springer Nature, 2021, pp. 998–1009,
doi:10.1038/s41593-021-00846-0.
short: W.F. Mlynarski, A.M. Hermundstad, Nature Neuroscience 24 (2021) 998–1009.
date_created: 2021-05-30T22:01:24Z
date_published: 2021-05-20T00:00:00Z
date_updated: 2023-08-08T13:51:14Z
day: '20'
department:
- _id: GaTk
doi: 10.1038/s41593-021-00846-0
ec_funded: 1
external_id:
isi:
- '000652577300003'
intvolume: ' 24'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: 'https://doi.org/10.1101/669200 '
month: '05'
oa: 1
oa_version: Preprint
page: 998-1009
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
publication: Nature Neuroscience
publication_identifier:
eissn:
- 1546-1726
issn:
- 1097-6256
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Efficient and adaptive sensory codes
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 24
year: '2021'
...
---
_id: '9441'
abstract:
- lang: eng
text: "Isomanifolds are the generalization of isosurfaces to arbitrary dimension
and codimension, i.e. submanifolds of ℝ^d defined as the zero set of some multivariate
multivalued smooth function f: ℝ^d → ℝ^{d-n}, where n is the intrinsic dimension
of the manifold. A natural way to approximate a smooth isomanifold M is to consider
its Piecewise-Linear (PL) approximation M̂ based on a triangulation \U0001D4AF
of the ambient space ℝ^d. In this paper, we describe a simple algorithm to trace
isomanifolds from a given starting point. The algorithm works for arbitrary dimensions
n and d, and any precision D. Our main result is that, when f (or M) has bounded
complexity, the complexity of the algorithm is polynomial in d and δ = 1/D (and
unavoidably exponential in n). Since it is known that for δ = Ω (d^{2.5}), M̂
is O(D²)-close and isotopic to M, our algorithm produces a faithful PL-approximation
of isomanifolds of bounded complexity in time polynomial in d. Combining this
algorithm with dimensionality reduction techniques, the dependency on d in the
size of M̂ can be completely removed with high probability. We also show that
the algorithm can handle isomanifolds with boundary and, more generally, isostratifolds.
The algorithm for isomanifolds with boundary has been implemented and experimental
results are reported, showing that it is practical and can handle cases that are
far ahead of the state-of-the-art. "
acknowledgement: We thank Dominique Attali, Guilherme de Fonseca, Arijit Ghosh, Vincent
Pilaud and Aurélien Alvarez for their comments and suggestions. We also acknowledge
the reviewers.
alternative_title:
- LIPIcs
article_processing_charge: No
author:
- first_name: Jean-Daniel
full_name: Boissonnat, Jean-Daniel
last_name: Boissonnat
- first_name: Siargey
full_name: Kachanovich, Siargey
last_name: Kachanovich
- first_name: Mathijs
full_name: Wintraecken, Mathijs
id: 307CFBC8-F248-11E8-B48F-1D18A9856A87
last_name: Wintraecken
orcid: 0000-0002-7472-2220
citation:
ama: 'Boissonnat J-D, Kachanovich S, Wintraecken M. Tracing isomanifolds in Rd in
time polynomial in d using Coxeter-Freudenthal-Kuhn triangulations. In: 37th
International Symposium on Computational Geometry (SoCG 2021). Vol 189. Leibniz
International Proceedings in Informatics (LIPIcs). Dagstuhl, Germany: Schloss
Dagstuhl - Leibniz-Zentrum für Informatik; 2021:17:1-17:16. doi:10.4230/LIPIcs.SoCG.2021.17'
apa: 'Boissonnat, J.-D., Kachanovich, S., & Wintraecken, M. (2021). Tracing
isomanifolds in Rd in time polynomial in d using Coxeter-Freudenthal-Kuhn triangulations.
In 37th International Symposium on Computational Geometry (SoCG 2021) (Vol.
189, p. 17:1-17:16). Dagstuhl, Germany: Schloss Dagstuhl - Leibniz-Zentrum für
Informatik. https://doi.org/10.4230/LIPIcs.SoCG.2021.17'
chicago: 'Boissonnat, Jean-Daniel, Siargey Kachanovich, and Mathijs Wintraecken.
“Tracing Isomanifolds in Rd in Time Polynomial in d Using Coxeter-Freudenthal-Kuhn
Triangulations.” In 37th International Symposium on Computational Geometry
(SoCG 2021), 189:17:1-17:16. Leibniz International Proceedings in Informatics
(LIPIcs). Dagstuhl, Germany: Schloss Dagstuhl - Leibniz-Zentrum für Informatik,
2021. https://doi.org/10.4230/LIPIcs.SoCG.2021.17.'
ieee: J.-D. Boissonnat, S. Kachanovich, and M. Wintraecken, “Tracing isomanifolds
in Rd in time polynomial in d using Coxeter-Freudenthal-Kuhn triangulations,”
in 37th International Symposium on Computational Geometry (SoCG 2021),
Virtual, 2021, vol. 189, p. 17:1-17:16.
ista: 'Boissonnat J-D, Kachanovich S, Wintraecken M. 2021. Tracing isomanifolds
in Rd in time polynomial in d using Coxeter-Freudenthal-Kuhn triangulations. 37th
International Symposium on Computational Geometry (SoCG 2021). SoCG: Symposium
on Computational GeometryLeibniz International Proceedings in Informatics (LIPIcs),
LIPIcs, vol. 189, 17:1-17:16.'
mla: Boissonnat, Jean-Daniel, et al. “Tracing Isomanifolds in Rd in Time Polynomial
in d Using Coxeter-Freudenthal-Kuhn Triangulations.” 37th International Symposium
on Computational Geometry (SoCG 2021), vol. 189, Schloss Dagstuhl - Leibniz-Zentrum
für Informatik, 2021, p. 17:1-17:16, doi:10.4230/LIPIcs.SoCG.2021.17.
short: J.-D. Boissonnat, S. Kachanovich, M. Wintraecken, in:, 37th International
Symposium on Computational Geometry (SoCG 2021), Schloss Dagstuhl - Leibniz-Zentrum
für Informatik, Dagstuhl, Germany, 2021, p. 17:1-17:16.
conference:
end_date: 2021-06-11
location: Virtual
name: 'SoCG: Symposium on Computational Geometry'
start_date: 2021-06-07
date_created: 2021-06-02T10:10:55Z
date_published: 2021-06-02T00:00:00Z
date_updated: 2023-10-10T07:34:34Z
day: '02'
ddc:
- '005'
- '516'
- '514'
department:
- _id: HeEd
doi: 10.4230/LIPIcs.SoCG.2021.17
ec_funded: 1
file:
- access_level: open_access
checksum: c322aa48d5d35a35877896cc565705b6
content_type: application/pdf
creator: mwintrae
date_created: 2021-06-02T10:22:33Z
date_updated: 2021-06-02T10:22:33Z
file_id: '9442'
file_name: LIPIcs-SoCG-2021-17.pdf
file_size: 1972902
relation: main_file
success: 1
file_date_updated: 2021-06-02T10:22:33Z
has_accepted_license: '1'
intvolume: ' 189'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
page: 17:1-17:16
place: Dagstuhl, Germany
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
publication: 37th International Symposium on Computational Geometry (SoCG 2021)
publication_identifier:
isbn:
- 978-3-95977-184-9
issn:
- 1868-8969
publication_status: published
publisher: Schloss Dagstuhl - Leibniz-Zentrum für Informatik
quality_controlled: '1'
related_material:
record:
- id: '12960'
relation: later_version
status: public
series_title: Leibniz International Proceedings in Informatics (LIPIcs)
status: public
title: Tracing isomanifolds in Rd in time polynomial in d using Coxeter-Freudenthal-Kuhn
triangulations
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: conference
user_id: D865714E-FA4E-11E9-B85B-F5C5E5697425
volume: 189
year: '2021'
...
---
_id: '9443'
abstract:
- lang: eng
text: Endoplasmic reticulum–plasma membrane contact sites (ER–PM CS) play fundamental
roles in all eukaryotic cells. Arabidopsis thaliana mutants lacking the ER–PM
protein tether synaptotagmin1 (SYT1) exhibit decreased PM integrity under multiple
abiotic stresses, such as freezing, high salt, osmotic stress, and mechanical
damage. Here, we show that, together with SYT1, the stress-induced SYT3 is an
ER–PM tether that also functions in maintaining PM integrity. The ER–PM CS localization
of SYT1 and SYT3 is dependent on PM phosphatidylinositol-4-phosphate and is regulated
by abiotic stress. Lipidomic analysis revealed that cold stress increased the
accumulation of diacylglycerol at the PM in a syt1/3 double mutant relative to
wild-type while the levels of most glycerolipid species remain unchanged. In addition,
the SYT1-green fluorescent protein fusion preferentially binds diacylglycerol
in vivo with little affinity for polar glycerolipids. Our work uncovers a SYT-dependent
mechanism of stress adaptation counteracting the detrimental accumulation of diacylglycerol
at the PM produced during episodes of abiotic stress.
acknowledgement: "We would also like to thank Lothar Willmitzer for the lipidomic
analysis at the Max Planck Institute of Molecular Plant Physiology (Potsdam, Germany).
We thank Manuela Vega from SCI for her technical assistance in image analysis. We
thank John R. Pearson and the Bionand Nanoimaging Unit, F. David Navas Fernández
and the SCAI Imaging Facility and The Plant Cell Biology facility at the Shanghai
Center for Plant Stress Biology for assistance with confocal microscopy. The FaFAH1
clone was a gift from Iraida Amaya Saavedra (IFAPA-Centro de Churriana, Málaga,
Spain). The AHA3 antibody against the H+-ATPase was a gift from Ramón Serrano Salom
(Instituto de Biología Molecular y Celular de Plantas, Valencia, Spain). The MAP-mTU2-SAC1
construct was provided by Yvon Jaillais (Laboratoire Reproduction et Développement
des Plantes, Univ Lyon, France). The pGWB5 from the pGWB vector series, was provided
by Tsuyoshi Nakagawa (Department of Molecular and Functional Genomics, Shimane University).
We thank Plan Propio from the University of Málaga for financial support.\r\nFunding"
article_processing_charge: No
article_type: original
author:
- first_name: N
full_name: Ruiz-Lopez, N
last_name: Ruiz-Lopez
- first_name: J
full_name: Pérez-Sancho, J
last_name: Pérez-Sancho
- first_name: A
full_name: Esteban Del Valle, A
last_name: Esteban Del Valle
- first_name: RP
full_name: Haslam, RP
last_name: Haslam
- first_name: S
full_name: Vanneste, S
last_name: Vanneste
- first_name: R
full_name: Catalá, R
last_name: Catalá
- first_name: C
full_name: Perea-Resa, C
last_name: Perea-Resa
- first_name: D
full_name: Van Damme, D
last_name: Van Damme
- first_name: S
full_name: García-Hernández, S
last_name: García-Hernández
- first_name: A
full_name: Albert, A
last_name: Albert
- first_name: J
full_name: Vallarino, J
last_name: Vallarino
- first_name: J
full_name: Lin, J
last_name: Lin
- first_name: Jiří
full_name: Friml, Jiří
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: AP
full_name: Macho, AP
last_name: Macho
- first_name: J
full_name: Salinas, J
last_name: Salinas
- first_name: A
full_name: Rosado, A
last_name: Rosado
- first_name: JA
full_name: Napier, JA
last_name: Napier
- first_name: V
full_name: Amorim-Silva, V
last_name: Amorim-Silva
- first_name: MA
full_name: Botella, MA
last_name: Botella
citation:
ama: Ruiz-Lopez N, Pérez-Sancho J, Esteban Del Valle A, et al. Synaptotagmins at
the endoplasmic reticulum-plasma membrane contact sites maintain diacylglycerol
homeostasis during abiotic stress. Plant Cell. 2021;33(7):2431-2453. doi:10.1093/plcell/koab122
apa: Ruiz-Lopez, N., Pérez-Sancho, J., Esteban Del Valle, A., Haslam, R., Vanneste,
S., Catalá, R., … Botella, M. (2021). Synaptotagmins at the endoplasmic reticulum-plasma
membrane contact sites maintain diacylglycerol homeostasis during abiotic stress.
Plant Cell. American Society of Plant Biologists. https://doi.org/10.1093/plcell/koab122
chicago: Ruiz-Lopez, N, J Pérez-Sancho, A Esteban Del Valle, RP Haslam, S Vanneste,
R Catalá, C Perea-Resa, et al. “Synaptotagmins at the Endoplasmic Reticulum-Plasma
Membrane Contact Sites Maintain Diacylglycerol Homeostasis during Abiotic Stress.”
Plant Cell. American Society of Plant Biologists, 2021. https://doi.org/10.1093/plcell/koab122.
ieee: N. Ruiz-Lopez et al., “Synaptotagmins at the endoplasmic reticulum-plasma
membrane contact sites maintain diacylglycerol homeostasis during abiotic stress,”
Plant Cell, vol. 33, no. 7. American Society of Plant Biologists, pp. 2431–2453,
2021.
ista: Ruiz-Lopez N, Pérez-Sancho J, Esteban Del Valle A, Haslam R, Vanneste S, Catalá
R, Perea-Resa C, Van Damme D, García-Hernández S, Albert A, Vallarino J, Lin J,
Friml J, Macho A, Salinas J, Rosado A, Napier J, Amorim-Silva V, Botella M. 2021.
Synaptotagmins at the endoplasmic reticulum-plasma membrane contact sites maintain
diacylglycerol homeostasis during abiotic stress. Plant Cell. 33(7), 2431–2453.
mla: Ruiz-Lopez, N., et al. “Synaptotagmins at the Endoplasmic Reticulum-Plasma
Membrane Contact Sites Maintain Diacylglycerol Homeostasis during Abiotic Stress.”
Plant Cell, vol. 33, no. 7, American Society of Plant Biologists, 2021,
pp. 2431–53, doi:10.1093/plcell/koab122.
short: N. Ruiz-Lopez, J. Pérez-Sancho, A. Esteban Del Valle, R. Haslam, S. Vanneste,
R. Catalá, C. Perea-Resa, D. Van Damme, S. García-Hernández, A. Albert, J. Vallarino,
J. Lin, J. Friml, A. Macho, J. Salinas, A. Rosado, J. Napier, V. Amorim-Silva,
M. Botella, Plant Cell 33 (2021) 2431–2453.
date_created: 2021-06-02T13:13:58Z
date_published: 2021-07-01T00:00:00Z
date_updated: 2023-08-08T13:54:32Z
day: '01'
ddc:
- '580'
department:
- _id: JiFr
doi: 10.1093/plcell/koab122
ec_funded: 1
external_id:
isi:
- '000703938100026'
pmid:
- '33944955'
file:
- access_level: open_access
checksum: 22d596678d00310d793611864a6d0fcd
content_type: application/pdf
creator: cchlebak
date_created: 2021-10-14T13:36:38Z
date_updated: 2021-10-14T13:36:38Z
file_id: '10141'
file_name: 2021_PlantCell_RuizLopez.pdf
file_size: 2952028
relation: main_file
success: 1
file_date_updated: 2021-10-14T13:36:38Z
has_accepted_license: '1'
intvolume: ' 33'
isi: 1
issue: '7'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: 2431-2453
pmid: 1
project:
- _id: 261099A6-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '742985'
name: Tracing Evolution of Auxin Transport and Polarity in Plants
publication: Plant Cell
publication_identifier:
eissn:
- 1532-298x
issn:
- 1040-4651
publication_status: published
publisher: American Society of Plant Biologists
quality_controlled: '1'
scopus_import: '1'
status: public
title: Synaptotagmins at the endoplasmic reticulum-plasma membrane contact sites maintain
diacylglycerol homeostasis during abiotic stress
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 33
year: '2021'
...
---
_id: '9447'
abstract:
- lang: eng
text: 'Lithium bis(trifluoromethylsulfonyl)imide (LiTFSI) based water-in-salt electrolytes
(WiSEs) has recently emerged as a new promising class of electrolytes, primarily
owing to their wide electrochemical stability windows (~3–4 V), that by far exceed
the thermodynamic stability window of water (1.23 V). Upon increasing the salt
concentration towards superconcentration the onset of the oxygen evolution reaction
(OER) shifts more significantly than the hydrogen evolution reaction (HER) does.
The OER shift has been explained by the accumulation of hydrophobic anions blocking
water access to the electrode surface, hence by double layer theory. Here we demonstrate
that the processes during oxidation are much more complex, involving OER, carbon
and salt decomposition by OER intermediates, and salt precipitation upon local
oversaturation. The positive shift in the onset potential of oxidation currents
was elucidated by combining several advanced analysis techniques: rotating ring-disk
electrode voltammetry, online electrochemical mass spectrometry, and X-ray photoelectron
spectroscopy, using both dilute and superconcentrated electrolytes. The results
demonstrate the importance of reactive OER intermediates and surface films for
electrolyte and electrode stability and motivate further studies of the nature
of the electrode.'
article_number: '050550'
article_processing_charge: No
author:
- first_name: Marion
full_name: Maffre, Marion
last_name: Maffre
- first_name: Roza
full_name: Bouchal, Roza
last_name: Bouchal
- first_name: Stefan Alexander
full_name: Freunberger, Stefan Alexander
id: A8CA28E6-CE23-11E9-AD2D-EC27E6697425
last_name: Freunberger
orcid: 0000-0003-2902-5319
- first_name: Niklas
full_name: Lindahl, Niklas
last_name: Lindahl
- first_name: Patrik
full_name: Johansson, Patrik
last_name: Johansson
- first_name: Frédéric
full_name: Favier, Frédéric
last_name: Favier
- first_name: Olivier
full_name: Fontaine, Olivier
last_name: Fontaine
- first_name: Daniel
full_name: Bélanger, Daniel
last_name: Bélanger
citation:
ama: Maffre M, Bouchal R, Freunberger SA, et al. Investigation of electrochemical
and chemical processes occurring at positive potentials in “Water-in-Salt” electrolytes.
Journal of The Electrochemical Society. 2021;168(5). doi:10.1149/1945-7111/ac0300
apa: Maffre, M., Bouchal, R., Freunberger, S. A., Lindahl, N., Johansson, P., Favier,
F., … Bélanger, D. (2021). Investigation of electrochemical and chemical processes
occurring at positive potentials in “Water-in-Salt” electrolytes. Journal of
The Electrochemical Society. IOP Publishing. https://doi.org/10.1149/1945-7111/ac0300
chicago: Maffre, Marion, Roza Bouchal, Stefan Alexander Freunberger, Niklas Lindahl,
Patrik Johansson, Frédéric Favier, Olivier Fontaine, and Daniel Bélanger. “Investigation
of Electrochemical and Chemical Processes Occurring at Positive Potentials in
‘Water-in-Salt’ Electrolytes.” Journal of The Electrochemical Society.
IOP Publishing, 2021. https://doi.org/10.1149/1945-7111/ac0300.
ieee: M. Maffre et al., “Investigation of electrochemical and chemical processes
occurring at positive potentials in ‘Water-in-Salt’ electrolytes,” Journal
of The Electrochemical Society, vol. 168, no. 5. IOP Publishing, 2021.
ista: Maffre M, Bouchal R, Freunberger SA, Lindahl N, Johansson P, Favier F, Fontaine
O, Bélanger D. 2021. Investigation of electrochemical and chemical processes occurring
at positive potentials in “Water-in-Salt” electrolytes. Journal of The Electrochemical
Society. 168(5), 050550.
mla: Maffre, Marion, et al. “Investigation of Electrochemical and Chemical Processes
Occurring at Positive Potentials in ‘Water-in-Salt’ Electrolytes.” Journal
of The Electrochemical Society, vol. 168, no. 5, 050550, IOP Publishing, 2021,
doi:10.1149/1945-7111/ac0300.
short: M. Maffre, R. Bouchal, S.A. Freunberger, N. Lindahl, P. Johansson, F. Favier,
O. Fontaine, D. Bélanger, Journal of The Electrochemical Society 168 (2021).
date_created: 2021-06-03T09:58:38Z
date_published: 2021-05-01T00:00:00Z
date_updated: 2023-09-05T13:25:30Z
day: '01'
department:
- _id: StFr
doi: 10.1149/1945-7111/ac0300
external_id:
isi:
- '000657724200001'
intvolume: ' 168'
isi: 1
issue: '5'
keyword:
- Renewable Energy
- Sustainability and the Environment
- Electrochemistry
- Materials Chemistry
- Electronic
- Optical and Magnetic Materials
- Surfaces
- Coatings and Films
- Condensed Matter Physics
language:
- iso: eng
month: '05'
oa_version: None
publication: Journal of The Electrochemical Society
publication_identifier:
eissn:
- 1945-7111
issn:
- 0013-4651
publication_status: published
publisher: IOP Publishing
quality_controlled: '1'
status: public
title: Investigation of electrochemical and chemical processes occurring at positive
potentials in “Water-in-Salt” electrolytes
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 168
year: '2021'
...
---
_id: '9462'
abstract:
- lang: eng
text: We consider a system of N trapped bosons with repulsive interactions in a
combined semiclassical mean-field limit at positive temperature. We show that
the free energy is well approximated by the minimum of the Hartree free energy
functional – a natural extension of the Hartree energy functional to positive
temperatures. The Hartree free energy functional converges in the same limit to
a semiclassical free energy functional, and we show that the system displays Bose–Einstein
condensation if and only if it occurs in the semiclassical free energy functional.
This allows us to show that for weak coupling the critical temperature decreases
due to the repulsive interactions.
acknowledgement: Funding from the European Union's Horizon 2020 research and innovation
programme under the ERC grant agreement No 694227 (R.S.) and under the Marie Sklodowska-Curie
grant agreement No 836146 (A.D.) is gratefully acknowledged. A.D. acknowledges support
of the Swiss National Science Foundation through the Ambizione grant PZ00P2 185851.
article_number: '109096'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Andreas
full_name: Deuchert, Andreas
last_name: Deuchert
- first_name: Robert
full_name: Seiringer, Robert
id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
last_name: Seiringer
orcid: 0000-0002-6781-0521
citation:
ama: Deuchert A, Seiringer R. Semiclassical approximation and critical temperature
shift for weakly interacting trapped bosons. Journal of Functional Analysis.
2021;281(6). doi:10.1016/j.jfa.2021.109096
apa: Deuchert, A., & Seiringer, R. (2021). Semiclassical approximation and critical
temperature shift for weakly interacting trapped bosons. Journal of Functional
Analysis. Elsevier. https://doi.org/10.1016/j.jfa.2021.109096
chicago: Deuchert, Andreas, and Robert Seiringer. “Semiclassical Approximation and
Critical Temperature Shift for Weakly Interacting Trapped Bosons.” Journal
of Functional Analysis. Elsevier, 2021. https://doi.org/10.1016/j.jfa.2021.109096.
ieee: A. Deuchert and R. Seiringer, “Semiclassical approximation and critical temperature
shift for weakly interacting trapped bosons,” Journal of Functional Analysis,
vol. 281, no. 6. Elsevier, 2021.
ista: Deuchert A, Seiringer R. 2021. Semiclassical approximation and critical temperature
shift for weakly interacting trapped bosons. Journal of Functional Analysis. 281(6),
109096.
mla: Deuchert, Andreas, and Robert Seiringer. “Semiclassical Approximation and Critical
Temperature Shift for Weakly Interacting Trapped Bosons.” Journal of Functional
Analysis, vol. 281, no. 6, 109096, Elsevier, 2021, doi:10.1016/j.jfa.2021.109096.
short: A. Deuchert, R. Seiringer, Journal of Functional Analysis 281 (2021).
date_created: 2021-06-06T22:01:28Z
date_published: 2021-09-15T00:00:00Z
date_updated: 2023-08-08T13:56:27Z
day: '15'
department:
- _id: RoSe
doi: 10.1016/j.jfa.2021.109096
ec_funded: 1
external_id:
arxiv:
- '2009.00992'
isi:
- '000656508600008'
intvolume: ' 281'
isi: 1
issue: '6'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/2009.00992
month: '09'
oa: 1
oa_version: Preprint
project:
- _id: 25C6DC12-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '694227'
name: Analysis of quantum many-body systems
publication: Journal of Functional Analysis
publication_identifier:
eissn:
- 1096-0783
issn:
- 0022-1236
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Semiclassical approximation and critical temperature shift for weakly interacting
trapped bosons
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 281
year: '2021'
...
---
_id: '9464'
abstract:
- lang: eng
text: We firstly introduce the self-assembled growth of highly uniform Ge quantum
wires with controllable position, distance and length on patterned Si (001) substrates.
We then present the electrically tunable strong spin-orbit coupling, the first
Ge hole spin qubit and ultrafast operation of hole spin qubit in the Ge/Si quantum
wires.
acknowledgement: This work was supported by the National Key R&D Program of China
(Grant No. 2016YFA0301700) and the ERC Starting Grant no. 335497.
article_number: '9420817'
article_processing_charge: No
author:
- first_name: Fei
full_name: Gao, Fei
last_name: Gao
- first_name: Jie Yin
full_name: Zhang, Jie Yin
last_name: Zhang
- first_name: Jian Huan
full_name: Wang, Jian Huan
last_name: Wang
- first_name: Ming
full_name: Ming, Ming
last_name: Ming
- first_name: Tina
full_name: Wang, Tina
last_name: Wang
- first_name: Jian Jun
full_name: Zhang, Jian Jun
last_name: Zhang
- first_name: Hannes
full_name: Watzinger, Hannes
id: 35DF8E50-F248-11E8-B48F-1D18A9856A87
last_name: Watzinger
- first_name: Josip
full_name: Kukucka, Josip
id: 3F5D8856-F248-11E8-B48F-1D18A9856A87
last_name: Kukucka
- first_name: Lada
full_name: Vukušić, Lada
id: 31E9F056-F248-11E8-B48F-1D18A9856A87
last_name: Vukušić
orcid: 0000-0003-2424-8636
- first_name: Georgios
full_name: Katsaros, Georgios
id: 38DB5788-F248-11E8-B48F-1D18A9856A87
last_name: Katsaros
orcid: 0000-0001-8342-202X
- first_name: Ke
full_name: Wang, Ke
last_name: Wang
- first_name: Gang
full_name: Xu, Gang
last_name: Xu
- first_name: Hai Ou
full_name: Li, Hai Ou
last_name: Li
- first_name: Guo Ping
full_name: Guo, Guo Ping
last_name: Guo
citation:
ama: 'Gao F, Zhang JY, Wang JH, et al. Ge/Si quantum wires for quantum computing.
In: 2021 5th IEEE Electron Devices Technology and Manufacturing Conference,
EDTM 2021. IEEE; 2021. doi:10.1109/EDTM50988.2021.9420817'
apa: 'Gao, F., Zhang, J. Y., Wang, J. H., Ming, M., Wang, T., Zhang, J. J., … Guo,
G. P. (2021). Ge/Si quantum wires for quantum computing. In 2021 5th IEEE Electron
Devices Technology and Manufacturing Conference, EDTM 2021. Virtual, Online:
IEEE. https://doi.org/10.1109/EDTM50988.2021.9420817'
chicago: Gao, Fei, Jie Yin Zhang, Jian Huan Wang, Ming Ming, Tina Wang, Jian Jun
Zhang, Hannes Watzinger, et al. “Ge/Si Quantum Wires for Quantum Computing.” In
2021 5th IEEE Electron Devices Technology and Manufacturing Conference, EDTM
2021. IEEE, 2021. https://doi.org/10.1109/EDTM50988.2021.9420817.
ieee: F. Gao et al., “Ge/Si quantum wires for quantum computing,” in 2021
5th IEEE Electron Devices Technology and Manufacturing Conference, EDTM 2021,
Virtual, Online, 2021.
ista: 'Gao F, Zhang JY, Wang JH, Ming M, Wang T, Zhang JJ, Watzinger H, Kukucka
J, Vukušić L, Katsaros G, Wang K, Xu G, Li HO, Guo GP. 2021. Ge/Si quantum wires
for quantum computing. 2021 5th IEEE Electron Devices Technology and Manufacturing
Conference, EDTM 2021. EDTM: IEEE Electron Devices Technology and Manufacturing
Conference, 9420817.'
mla: Gao, Fei, et al. “Ge/Si Quantum Wires for Quantum Computing.” 2021 5th IEEE
Electron Devices Technology and Manufacturing Conference, EDTM 2021, 9420817,
IEEE, 2021, doi:10.1109/EDTM50988.2021.9420817.
short: F. Gao, J.Y. Zhang, J.H. Wang, M. Ming, T. Wang, J.J. Zhang, H. Watzinger,
J. Kukucka, L. Vukušić, G. Katsaros, K. Wang, G. Xu, H.O. Li, G.P. Guo, in:, 2021
5th IEEE Electron Devices Technology and Manufacturing Conference, EDTM 2021,
IEEE, 2021.
conference:
end_date: 2021-04-11
location: Virtual, Online
name: 'EDTM: IEEE Electron Devices Technology and Manufacturing Conference'
start_date: 2021-04-08
date_created: 2021-06-06T22:01:29Z
date_published: 2021-04-08T00:00:00Z
date_updated: 2023-10-03T12:51:59Z
day: '08'
department:
- _id: GeKa
doi: 10.1109/EDTM50988.2021.9420817
ec_funded: 1
external_id:
isi:
- '000675595800006'
isi: 1
language:
- iso: eng
month: '04'
oa_version: None
project:
- _id: 25517E86-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '335497'
name: Towards Spin qubits and Majorana fermions in Germanium selfassembled hut-wires
publication: 2021 5th IEEE Electron Devices Technology and Manufacturing Conference,
EDTM 2021
publication_identifier:
isbn:
- '9781728181769'
publication_status: published
publisher: IEEE
quality_controlled: '1'
scopus_import: '1'
status: public
title: Ge/Si quantum wires for quantum computing
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2021'
...
---
_id: '9465'
abstract:
- lang: eng
text: "Given a locally finite set \U0001D44B⊆ℝ\U0001D451 and an integer \U0001D458≥0,
we consider the function \U0001D430\U0001D458:Del\U0001D458(\U0001D44B)→ℝ on the
dual of the order-k Voronoi tessellation, whose sublevel sets generalize the notion
of alpha shapes from order-1 to order-k (Edelsbrunner et al. in IEEE Trans Inf
Theory IT-29:551–559, 1983; Krasnoshchekov and Polishchuk in Inf Process Lett
114:76–83, 2014). While this function is not necessarily generalized discrete
Morse, in the sense of Forman (Adv Math 134:90–145, 1998) and Freij (Discrete
Math 309:3821–3829, 2009), we prove that it satisfies similar properties so that
its increments can be meaningfully classified into critical and non-critical steps.
This result extends to the case of weighted points and sheds light on k-fold covers
with balls in Euclidean space."
article_number: '15'
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
- first_name: Anton
full_name: Nikitenko, Anton
id: 3E4FF1BA-F248-11E8-B48F-1D18A9856A87
last_name: Nikitenko
- first_name: Georg F
full_name: Osang, Georg F
id: 464B40D6-F248-11E8-B48F-1D18A9856A87
last_name: Osang
citation:
ama: Edelsbrunner H, Nikitenko A, Osang GF. A step in the Delaunay mosaic of order
k. Journal of Geometry. 2021;112(1). doi:10.1007/s00022-021-00577-4
apa: Edelsbrunner, H., Nikitenko, A., & Osang, G. F. (2021). A step in the Delaunay
mosaic of order k. Journal of Geometry. Springer Nature. https://doi.org/10.1007/s00022-021-00577-4
chicago: Edelsbrunner, Herbert, Anton Nikitenko, and Georg F Osang. “A Step in the
Delaunay Mosaic of Order K.” Journal of Geometry. Springer Nature, 2021.
https://doi.org/10.1007/s00022-021-00577-4.
ieee: H. Edelsbrunner, A. Nikitenko, and G. F. Osang, “A step in the Delaunay mosaic
of order k,” Journal of Geometry, vol. 112, no. 1. Springer Nature, 2021.
ista: Edelsbrunner H, Nikitenko A, Osang GF. 2021. A step in the Delaunay mosaic
of order k. Journal of Geometry. 112(1), 15.
mla: Edelsbrunner, Herbert, et al. “A Step in the Delaunay Mosaic of Order K.” Journal
of Geometry, vol. 112, no. 1, 15, Springer Nature, 2021, doi:10.1007/s00022-021-00577-4.
short: H. Edelsbrunner, A. Nikitenko, G.F. Osang, Journal of Geometry 112 (2021).
date_created: 2021-06-06T22:01:29Z
date_published: 2021-04-01T00:00:00Z
date_updated: 2022-05-12T11:41:45Z
day: '01'
ddc:
- '510'
department:
- _id: HeEd
doi: 10.1007/s00022-021-00577-4
file:
- access_level: open_access
checksum: e52a832f1def52a2b23d21bcc09e646f
content_type: application/pdf
creator: kschuh
date_created: 2021-06-11T13:16:26Z
date_updated: 2021-06-11T13:16:26Z
file_id: '9544'
file_name: 2021_Geometry_Edelsbrunner.pdf
file_size: 694706
relation: main_file
success: 1
file_date_updated: 2021-06-11T13:16:26Z
has_accepted_license: '1'
intvolume: ' 112'
issue: '1'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
publication: Journal of Geometry
publication_identifier:
eissn:
- '14208997'
issn:
- '00472468'
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: A step in the Delaunay mosaic of order k
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 112
year: '2021'
...
---
_id: '9466'
abstract:
- lang: eng
text: In this work, we apply the dynamical systems analysis of Hanrot et al. (CRYPTO’11)
to a class of lattice block reduction algorithms that includes (natural variants
of) slide reduction and block-Rankin reduction. This implies sharper bounds on
the polynomial running times (in the query model) for these algorithms and opens
the door to faster practical variants of slide reduction. We give heuristic arguments
showing that such variants can indeed speed up slide reduction significantly in
practice. This is confirmed by experimental evidence, which also shows that our
variants are competitive with state-of-the-art reduction algorithms.
acknowledgement: 'This work was initiated in discussions with Léo Ducas, when the
author was visiting the Simons Institute for the Theory of Computation during the
program “Lattices: Algorithms, Complexity, and Cryptography”. We thank Thomas Espitau
for pointing out a bug in a proof in an earlier version of this manuscript.'
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Michael
full_name: Walter, Michael
id: 488F98B0-F248-11E8-B48F-1D18A9856A87
last_name: Walter
orcid: 0000-0003-3186-2482
citation:
ama: 'Walter M. The convergence of slide-type reductions. In: Public-Key Cryptography
– PKC 2021. Vol 12710. Springer Nature; 2021:45-67. doi:10.1007/978-3-030-75245-3_3'
apa: 'Walter, M. (2021). The convergence of slide-type reductions. In Public-Key
Cryptography – PKC 2021 (Vol. 12710, pp. 45–67). Virtual: Springer Nature.
https://doi.org/10.1007/978-3-030-75245-3_3'
chicago: Walter, Michael. “The Convergence of Slide-Type Reductions.” In Public-Key
Cryptography – PKC 2021, 12710:45–67. Springer Nature, 2021. https://doi.org/10.1007/978-3-030-75245-3_3.
ieee: M. Walter, “The convergence of slide-type reductions,” in Public-Key Cryptography
– PKC 2021, Virtual, 2021, vol. 12710, pp. 45–67.
ista: 'Walter M. 2021. The convergence of slide-type reductions. Public-Key Cryptography
– PKC 2021. PKC: IACR International Conference on Practice and Theory of Public
Key Cryptography, LNCS, vol. 12710, 45–67.'
mla: Walter, Michael. “The Convergence of Slide-Type Reductions.” Public-Key
Cryptography – PKC 2021, vol. 12710, Springer Nature, 2021, pp. 45–67, doi:10.1007/978-3-030-75245-3_3.
short: M. Walter, in:, Public-Key Cryptography – PKC 2021, Springer Nature, 2021,
pp. 45–67.
conference:
end_date: 2021-05-13
location: Virtual
name: 'PKC: IACR International Conference on Practice and Theory of Public Key Cryptography'
start_date: 2021-05-10
date_created: 2021-06-06T22:01:29Z
date_published: 2021-05-01T00:00:00Z
date_updated: 2023-02-23T13:58:47Z
day: '01'
ddc:
- '000'
department:
- _id: KrPi
doi: 10.1007/978-3-030-75245-3_3
ec_funded: 1
file:
- access_level: open_access
checksum: 413e564d645ed93d7318672361d9d470
content_type: application/pdf
creator: dernst
date_created: 2022-05-27T09:48:31Z
date_updated: 2022-05-27T09:48:31Z
file_id: '11416'
file_name: 2021_PKC_Walter.pdf
file_size: 489017
relation: main_file
success: 1
file_date_updated: 2022-05-27T09:48:31Z
has_accepted_license: '1'
intvolume: ' 12710'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
page: 45-67
project:
- _id: 258AA5B2-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '682815'
name: Teaching Old Crypto New Tricks
publication: Public-Key Cryptography – PKC 2021
publication_identifier:
eissn:
- '16113349'
isbn:
- '9783030752446'
issn:
- '03029743'
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: The convergence of slide-type reductions
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 12710
year: '2021'
...
---
_id: '9467'
abstract:
- lang: eng
text: "Turbulence in the flow of fluid through a pipe can be suppressed by buoyancy
forces. As the suppression of turbulence leads to severe heat transfer deterioration,
this is an important and undesirable phenomenon in both heating and cooling applications.
Vertical flow is often considered, as the axial buoyancy force can help drive
the flow. With heating measured by the buoyancy parameter \U0001D436, our direct
numerical simulations show that shear-driven turbulence may either be completely
laminarised or it transitions to a relatively quiescent convection-driven state.
Buoyancy forces cause a flattening of the base flow profile, which in isothermal
pipe flow has recently been linked to complete suppression of turbulence (Kühnen
et al., Nat. Phys., vol. 14, 2018, pp. 386–390), and the flattened laminar base
profile has enhanced nonlinear stability (Marensi et al., J. Fluid Mech., vol.
863, 2019, pp. 50–875). In agreement with these findings, the nonlinear lower-branch
travelling-wave solution analysed here, which is believed to mediate transition
to turbulence in isothermal pipe flow, is shown to be suppressed by buoyancy.
A linear instability of the laminar base flow is responsible for the appearance
of the relatively quiescent convection driven state for \U0001D436≳4 across the
range of Reynolds numbers considered. In the suppression of turbulence, however,
i.e. in the transition from turbulence, we find clearer association with the analysis
of He et al. (J. Fluid Mech., vol. 809, 2016, pp. 31–71) than with the above dynamical
systems approach, which describes better the transition to turbulence. The laminarisation
criterion He et al. propose, based on an apparent Reynolds number of the flow
as measured by its driving pressure gradient, is found to capture the critical
\U0001D436=\U0001D436\U0001D450\U0001D45F(\U0001D445\U0001D452) above which the
flow will be laminarised or switch to the convection-driven type. Our analysis
suggests that it is the weakened rolls, rather than the streaks, which appear
to be critical for laminarisation."
acknowledgement: The anonymous referees are kindly acknowledged for their useful suggestions
andcomments.
article_number: A17
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Elena
full_name: Marensi, Elena
id: 0BE7553A-1004-11EA-B805-18983DDC885E
last_name: Marensi
- first_name: Shuisheng
full_name: He, Shuisheng
last_name: He
- first_name: Ashley P.
full_name: Willis, Ashley P.
last_name: Willis
citation:
ama: Marensi E, He S, Willis AP. Suppression of turbulence and travelling waves
in a vertical heated pipe. Journal of Fluid Mechanics. 2021;919. doi:10.1017/jfm.2021.371
apa: Marensi, E., He, S., & Willis, A. P. (2021). Suppression of turbulence
and travelling waves in a vertical heated pipe. Journal of Fluid Mechanics.
Cambridge University Press. https://doi.org/10.1017/jfm.2021.371
chicago: Marensi, Elena, Shuisheng He, and Ashley P. Willis. “Suppression of Turbulence
and Travelling Waves in a Vertical Heated Pipe.” Journal of Fluid Mechanics.
Cambridge University Press, 2021. https://doi.org/10.1017/jfm.2021.371.
ieee: E. Marensi, S. He, and A. P. Willis, “Suppression of turbulence and travelling
waves in a vertical heated pipe,” Journal of Fluid Mechanics, vol. 919.
Cambridge University Press, 2021.
ista: Marensi E, He S, Willis AP. 2021. Suppression of turbulence and travelling
waves in a vertical heated pipe. Journal of Fluid Mechanics. 919, A17.
mla: Marensi, Elena, et al. “Suppression of Turbulence and Travelling Waves in a
Vertical Heated Pipe.” Journal of Fluid Mechanics, vol. 919, A17, Cambridge
University Press, 2021, doi:10.1017/jfm.2021.371.
short: E. Marensi, S. He, A.P. Willis, Journal of Fluid Mechanics 919 (2021).
date_created: 2021-06-06T22:01:30Z
date_published: 2021-07-25T00:00:00Z
date_updated: 2023-08-08T13:58:41Z
day: '25'
ddc:
- '530'
department:
- _id: BjHo
doi: 10.1017/jfm.2021.371
external_id:
arxiv:
- '2008.13486'
isi:
- '000653785000001'
file:
- access_level: open_access
checksum: 867ad077e45c181c2c5ec1311ba27c41
content_type: application/pdf
creator: kschuh
date_created: 2021-08-03T09:53:28Z
date_updated: 2021-08-03T09:53:28Z
file_id: '9766'
file_name: 2021_JournalFluidMechanics_Marensi.pdf
file_size: 4087358
relation: main_file
success: 1
file_date_updated: 2021-08-03T09:53:28Z
has_accepted_license: '1'
intvolume: ' 919'
isi: 1
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
publication: Journal of Fluid Mechanics
publication_identifier:
eissn:
- '14697645'
issn:
- '00221120'
publication_status: published
publisher: Cambridge University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Suppression of turbulence and travelling waves in a vertical heated pipe
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 919
year: '2021'
...
---
_id: '9468'
abstract:
- lang: eng
text: "Motivated by the successful application of geometry to proving the Harary--Hill
conjecture for “pseudolinear” drawings of $K_n$, we introduce “pseudospherical”
drawings of graphs. A spherical drawing of a graph $G$ is a drawing in the unit
sphere $\\mathbb{S}^2$ in which the vertices of $G$ are represented as points---no
three on a great circle---and the edges of $G$ are shortest-arcs in $\\mathbb{S}^2$
connecting pairs of vertices. Such a drawing has three properties: (1) every edge
$e$ is contained in a simple closed curve $\\gamma_e$ such that the only vertices
in $\\gamma_e$ are the ends of $e$; (2) if $e\\ne f$, then $\\gamma_e\\cap\\gamma_f$
has precisely two crossings; and (3) if $e\\ne f$, then $e$ intersects $\\gamma_f$
at most once, in either a crossing or an end of $e$. We use properties (1)--(3)
to define a pseudospherical drawing of $G$. Our main result is that for the complete
graph, properties (1)--(3) are equivalent to the same three properties but with
“precisely two crossings” in (2) replaced by “at most two crossings.” The proof
requires a result in the geometric transversal theory of arrangements of pseudocircles.
This is proved using the surprising result that the absence of special arcs (coherent
spirals) in an arrangement of simple closed curves characterizes the fact that
any two curves in the arrangement have at most two crossings. Our studies provide
the necessary ideas for exhibiting a drawing of $K_{10}$ that has no extension
to an arrangement of pseudocircles and a drawing of $K_9$ that does extend to
an arrangement of pseudocircles, but no such extension has all pairs of pseudocircles
crossing twice.\r\n"
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Alan M
full_name: Arroyo Guevara, Alan M
id: 3207FDC6-F248-11E8-B48F-1D18A9856A87
last_name: Arroyo Guevara
orcid: 0000-0003-2401-8670
- first_name: R. Bruce
full_name: Richter, R. Bruce
last_name: Richter
- first_name: Matthew
full_name: Sunohara, Matthew
last_name: Sunohara
citation:
ama: Arroyo Guevara AM, Richter RB, Sunohara M. Extending drawings of complete graphs
into arrangements of pseudocircles. SIAM Journal on Discrete Mathematics.
2021;35(2):1050-1076. doi:10.1137/20M1313234
apa: Arroyo Guevara, A. M., Richter, R. B., & Sunohara, M. (2021). Extending
drawings of complete graphs into arrangements of pseudocircles. SIAM Journal
on Discrete Mathematics. Society for Industrial and Applied Mathematics. https://doi.org/10.1137/20M1313234
chicago: Arroyo Guevara, Alan M, R. Bruce Richter, and Matthew Sunohara. “Extending
Drawings of Complete Graphs into Arrangements of Pseudocircles.” SIAM Journal
on Discrete Mathematics. Society for Industrial and Applied Mathematics, 2021.
https://doi.org/10.1137/20M1313234.
ieee: A. M. Arroyo Guevara, R. B. Richter, and M. Sunohara, “Extending drawings
of complete graphs into arrangements of pseudocircles,” SIAM Journal on Discrete
Mathematics, vol. 35, no. 2. Society for Industrial and Applied Mathematics,
pp. 1050–1076, 2021.
ista: Arroyo Guevara AM, Richter RB, Sunohara M. 2021. Extending drawings of complete
graphs into arrangements of pseudocircles. SIAM Journal on Discrete Mathematics.
35(2), 1050–1076.
mla: Arroyo Guevara, Alan M., et al. “Extending Drawings of Complete Graphs into
Arrangements of Pseudocircles.” SIAM Journal on Discrete Mathematics, vol.
35, no. 2, Society for Industrial and Applied Mathematics, 2021, pp. 1050–76,
doi:10.1137/20M1313234.
short: A.M. Arroyo Guevara, R.B. Richter, M. Sunohara, SIAM Journal on Discrete
Mathematics 35 (2021) 1050–1076.
date_created: 2021-06-06T22:01:30Z
date_published: 2021-05-20T00:00:00Z
date_updated: 2023-08-08T13:58:12Z
day: '20'
department:
- _id: UlWa
doi: 10.1137/20M1313234
ec_funded: 1
external_id:
arxiv:
- '2001.06053'
isi:
- '000674142200022'
intvolume: ' 35'
isi: 1
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/2001.06053
month: '05'
oa: 1
oa_version: Preprint
page: 1050-1076
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
publication: SIAM Journal on Discrete Mathematics
publication_identifier:
issn:
- '08954801'
publication_status: published
publisher: Society for Industrial and Applied Mathematics
quality_controlled: '1'
scopus_import: '1'
status: public
title: Extending drawings of complete graphs into arrangements of pseudocircles
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 35
year: '2021'
...
---
_id: '9469'
abstract:
- lang: eng
text: In this paper, we consider reflected three-operator splitting methods for
monotone inclusion problems in real Hilbert spaces. To do this, we first obtain
weak convergence analysis and nonasymptotic O(1/n) convergence rate of the reflected
Krasnosel'skiĭ-Mann iteration for finding a fixed point of nonexpansive mapping
in real Hilbert spaces under some seemingly easy to implement conditions on the
iterative parameters. We then apply our results to three-operator splitting for
the monotone inclusion problem and consequently obtain the corresponding convergence
analysis. Furthermore, we derive reflected primal-dual algorithms for highly structured
monotone inclusion problems. Some numerical implementations are drawn from splitting
methods to support the theoretical analysis.
acknowledgement: The authors are grateful to the anonymous referees and the handling
Editor for their insightful comments which have improved the earlier version of
the manuscript greatly. The second author is grateful to the University of Hafr
Al Batin. The last author has received funding from the European Research Council
(ERC) under the European Union's Seventh Framework Program (FP7-2007-2013) (Grant
agreement No. 616160).
article_processing_charge: No
article_type: original
author:
- first_name: Olaniyi S.
full_name: Iyiola, Olaniyi S.
last_name: Iyiola
- first_name: Cyril D.
full_name: Enyi, Cyril D.
last_name: Enyi
- first_name: Yekini
full_name: Shehu, Yekini
id: 3FC7CB58-F248-11E8-B48F-1D18A9856A87
last_name: Shehu
orcid: 0000-0001-9224-7139
citation:
ama: Iyiola OS, Enyi CD, Shehu Y. Reflected three-operator splitting method for
monotone inclusion problem. Optimization Methods and Software. 2021. doi:10.1080/10556788.2021.1924715
apa: Iyiola, O. S., Enyi, C. D., & Shehu, Y. (2021). Reflected three-operator
splitting method for monotone inclusion problem. Optimization Methods and Software.
Taylor and Francis. https://doi.org/10.1080/10556788.2021.1924715
chicago: Iyiola, Olaniyi S., Cyril D. Enyi, and Yekini Shehu. “Reflected Three-Operator
Splitting Method for Monotone Inclusion Problem.” Optimization Methods and
Software. Taylor and Francis, 2021. https://doi.org/10.1080/10556788.2021.1924715.
ieee: O. S. Iyiola, C. D. Enyi, and Y. Shehu, “Reflected three-operator splitting
method for monotone inclusion problem,” Optimization Methods and Software.
Taylor and Francis, 2021.
ista: Iyiola OS, Enyi CD, Shehu Y. 2021. Reflected three-operator splitting method
for monotone inclusion problem. Optimization Methods and Software.
mla: Iyiola, Olaniyi S., et al. “Reflected Three-Operator Splitting Method for Monotone
Inclusion Problem.” Optimization Methods and Software, Taylor and Francis,
2021, doi:10.1080/10556788.2021.1924715.
short: O.S. Iyiola, C.D. Enyi, Y. Shehu, Optimization Methods and Software (2021).
date_created: 2021-06-06T22:01:30Z
date_published: 2021-05-12T00:00:00Z
date_updated: 2023-08-08T13:57:43Z
day: '12'
department:
- _id: VlKo
doi: 10.1080/10556788.2021.1924715
ec_funded: 1
external_id:
isi:
- '000650507600001'
isi: 1
language:
- iso: eng
month: '05'
oa_version: None
project:
- _id: 25FBA906-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '616160'
name: 'Discrete Optimization in Computer Vision: Theory and Practice'
publication: Optimization Methods and Software
publication_identifier:
eissn:
- 1029-4937
issn:
- 1055-6788
publication_status: published
publisher: Taylor and Francis
quality_controlled: '1'
scopus_import: '1'
status: public
title: Reflected three-operator splitting method for monotone inclusion problem
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
year: '2021'
...
---
_id: '9470'
abstract:
- lang: eng
text: A key step in understanding the genetic basis of different evolutionary outcomes
(e.g., adaptation) is to determine the roles played by different mutation types
(e.g., SNPs, translocations and inversions). To do this we must simultaneously
consider different mutation types in an evolutionary framework. Here, we propose
a research framework that directly utilizes the most important characteristics
of mutations, their population genetic effects, to determine their relative evolutionary
significance in a given scenario. We review known population genetic effects of
different mutation types and show how these may be connected to different evolutionary
outcomes. We provide examples of how to implement this framework and pinpoint
areas where more data, theory and synthesis are needed. Linking experimental and
theoretical approaches to examine different mutation types simultaneously is a
critical step towards understanding their evolutionary significance.
acknowledgement: We thank the editor, two helpful reviewers, Roger Butlin, Kerstin
Johannesson, Valentina Peona, Rike Stelkens, Julie Blommaert, Nick Barton, and João
Alpedrinha for helpful comments that improved the manuscript. The authors acknowledge
funding from the Swedish Research Council Formas (2017-01597 to AS), the Swedish
Research Council Vetenskapsrådet (2016-05139 to AS, 2019-04452 to TS) and from the
European Research Council (ERC) under the European Union’s Horizon 2020 research
and innovation programme (grant agreement no. 757451 to TS). ELB was funded by a
Carl Tryggers grant awarded to Tanja Slotte. Anja M. Westram was funded by the European
Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie
grant agreement No 797747. Inês Fragata was funded by a Junior Researcher contract
from FCT (CEECIND/02616/2018).
article_processing_charge: No
author:
- first_name: Emma L.
full_name: Berdan, Emma L.
last_name: Berdan
- first_name: Alexandre
full_name: Blanckaert, Alexandre
last_name: Blanckaert
- first_name: Tanja
full_name: Slotte, Tanja
last_name: Slotte
- first_name: Alexander
full_name: Suh, Alexander
last_name: Suh
- first_name: Anja M
full_name: Westram, Anja M
id: 3C147470-F248-11E8-B48F-1D18A9856A87
last_name: Westram
orcid: 0000-0003-1050-4969
- first_name: Inês
full_name: Fragata, Inês
last_name: Fragata
citation:
ama: 'Berdan EL, Blanckaert A, Slotte T, Suh A, Westram AM, Fragata I. Unboxing
mutations: Connecting mutation types with evolutionary consequences. Molecular
Ecology. 2021;30(12):2710-2723. doi:10.1111/mec.15936'
apa: 'Berdan, E. L., Blanckaert, A., Slotte, T., Suh, A., Westram, A. M., &
Fragata, I. (2021). Unboxing mutations: Connecting mutation types with evolutionary
consequences. Molecular Ecology. Wiley. https://doi.org/10.1111/mec.15936'
chicago: 'Berdan, Emma L., Alexandre Blanckaert, Tanja Slotte, Alexander Suh, Anja
M Westram, and Inês Fragata. “Unboxing Mutations: Connecting Mutation Types with
Evolutionary Consequences.” Molecular Ecology. Wiley, 2021. https://doi.org/10.1111/mec.15936.'
ieee: 'E. L. Berdan, A. Blanckaert, T. Slotte, A. Suh, A. M. Westram, and I. Fragata,
“Unboxing mutations: Connecting mutation types with evolutionary consequences,”
Molecular Ecology, vol. 30, no. 12. Wiley, pp. 2710–2723, 2021.'
ista: 'Berdan EL, Blanckaert A, Slotte T, Suh A, Westram AM, Fragata I. 2021. Unboxing
mutations: Connecting mutation types with evolutionary consequences. Molecular
Ecology. 30(12), 2710–2723.'
mla: 'Berdan, Emma L., et al. “Unboxing Mutations: Connecting Mutation Types with
Evolutionary Consequences.” Molecular Ecology, vol. 30, no. 12, Wiley,
2021, pp. 2710–23, doi:10.1111/mec.15936.'
short: E.L. Berdan, A. Blanckaert, T. Slotte, A. Suh, A.M. Westram, I. Fragata,
Molecular Ecology 30 (2021) 2710–2723.
date_created: 2021-06-06T22:01:31Z
date_published: 2021-06-01T00:00:00Z
date_updated: 2023-08-08T13:59:18Z
day: '01'
ddc:
- '570'
department:
- _id: NiBa
doi: 10.1111/mec.15936
ec_funded: 1
external_id:
isi:
- '000652056400001'
file:
- access_level: open_access
checksum: e6f4731365bde2614b333040a08265d8
content_type: application/pdf
creator: kschuh
date_created: 2021-06-11T15:34:53Z
date_updated: 2021-06-11T15:34:53Z
file_id: '9545'
file_name: 2021_MolecularEcology_Berdan.pdf
file_size: 1031978
relation: main_file
success: 1
file_date_updated: 2021-06-11T15:34:53Z
has_accepted_license: '1'
intvolume: ' 30'
isi: 1
issue: '12'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc/4.0/
month: '06'
oa: 1
oa_version: Published Version
page: 2710-2723
project:
- _id: 265B41B8-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '797747'
name: Theoretical and empirical approaches to understanding Parallel Adaptation
publication: Molecular Ecology
publication_identifier:
eissn:
- 1365294X
issn:
- '09621083'
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Unboxing mutations: Connecting mutation types with evolutionary consequences'
tmp:
image: /images/cc_by_nc.png
legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
short: CC BY-NC (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 30
year: '2021'
...
---
_id: '9541'
abstract:
- lang: eng
text: The Massively Parallel Computation (MPC) model is an emerging model that distills
core aspects of distributed and parallel computation, developed as a tool to solve
combinatorial (typically graph) problems in systems of many machines with limited
space. Recent work has focused on the regime in which machines have sublinear
(in n, the number of nodes in the input graph) space, with randomized algorithms
presented for the fundamental problems of Maximal Matching and Maximal Independent
Set. However, there have been no prior corresponding deterministic algorithms.
A major challenge underlying the sublinear space setting is that the local space
of each machine might be too small to store all edges incident to a single node.
This poses a considerable obstacle compared to classical models in which each
node is assumed to know and have easy access to its incident edges. To overcome
this barrier, we introduce a new graph sparsification technique that deterministically
computes a low-degree subgraph, with the additional property that solving the
problem on this subgraph provides significant progress towards solving the problem
for the original input graph. Using this framework to derandomize the well-known
algorithm of Luby [SICOMP’86], we obtain O(log Δ + log log n)-round deterministic
MPC algorithms for solving the problems of Maximal Matching and Maximal Independent
Set with O(nɛ) space on each machine for any constant ɛ > 0. These algorithms
also run in O(log Δ) rounds in the closely related model of CONGESTED CLIQUE,
improving upon the state-of-the-art bound of O(log 2Δ) rounds by Censor-Hillel
et al. [DISC’17].
acknowledgement: "Institute of Science and Technology Austria (IST Austria). Email:
peter.davies@ist.ac.at. Work partially\r\ndone at the Department of Computer Science
and Centre for Discrete Mathematics and its Applications (DIMAP),University of Warwick.
Research partially supported by the European Union’s Horizon 2020 research and innovation
programme under the Marie Skłodowska-Curie grant agreement No 754411, the Centre
for Discrete Mathematics and its Applications, a Weizmann-UK Making Connections
Grant, and EPSRC award EP/N011163/1."
article_number: '16'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Artur
full_name: Czumaj, Artur
last_name: Czumaj
- first_name: Peter
full_name: Davies, Peter
id: 11396234-BB50-11E9-B24C-90FCE5697425
last_name: Davies
orcid: 0000-0002-5646-9524
- first_name: Merav
full_name: Parter, Merav
last_name: Parter
citation:
ama: Czumaj A, Davies P, Parter M. Graph sparsification for derandomizing massively
parallel computation with low space. ACM Transactions on Algorithms. 2021;17(2).
doi:10.1145/3451992
apa: Czumaj, A., Davies, P., & Parter, M. (2021). Graph sparsification for derandomizing
massively parallel computation with low space. ACM Transactions on Algorithms.
Association for Computing Machinery. https://doi.org/10.1145/3451992
chicago: Czumaj, Artur, Peter Davies, and Merav Parter. “Graph Sparsification for
Derandomizing Massively Parallel Computation with Low Space.” ACM Transactions
on Algorithms. Association for Computing Machinery, 2021. https://doi.org/10.1145/3451992.
ieee: A. Czumaj, P. Davies, and M. Parter, “Graph sparsification for derandomizing
massively parallel computation with low space,” ACM Transactions on Algorithms,
vol. 17, no. 2. Association for Computing Machinery, 2021.
ista: Czumaj A, Davies P, Parter M. 2021. Graph sparsification for derandomizing
massively parallel computation with low space. ACM Transactions on Algorithms.
17(2), 16.
mla: Czumaj, Artur, et al. “Graph Sparsification for Derandomizing Massively Parallel
Computation with Low Space.” ACM Transactions on Algorithms, vol. 17, no.
2, 16, Association for Computing Machinery, 2021, doi:10.1145/3451992.
short: A. Czumaj, P. Davies, M. Parter, ACM Transactions on Algorithms 17 (2021).
date_created: 2021-06-10T19:31:05Z
date_published: 2021-06-01T00:00:00Z
date_updated: 2024-02-28T12:53:09Z
day: '01'
ddc:
- '000'
department:
- _id: DaAl
doi: 10.1145/3451992
ec_funded: 1
external_id:
arxiv:
- '1912.05390'
isi:
- '000661311300006'
file:
- access_level: open_access
checksum: a21c627683890c309a68f6389302c408
content_type: application/pdf
creator: pdavies
date_created: 2021-06-10T19:33:56Z
date_updated: 2021-06-10T19:33:56Z
file_id: '9542'
file_name: MISMM-arxiv.pdf
file_size: 587404
relation: main_file
success: 1
file_date_updated: 2021-06-10T19:33:56Z
has_accepted_license: '1'
intvolume: ' 17'
isi: 1
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1912.05390
month: '06'
oa: 1
oa_version: Submitted Version
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
publication: ACM Transactions on Algorithms
publication_identifier:
eissn:
- 1549-6333
issn:
- 1549-6325
publication_status: published
publisher: Association for Computing Machinery
quality_controlled: '1'
related_material:
record:
- id: '7802'
relation: earlier_version
status: public
status: public
title: Graph sparsification for derandomizing massively parallel computation with
low space
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 17
year: '2021'
...
---
_id: '9543'
abstract:
- lang: eng
text: We consider the problem ofdistributed mean estimation (DME), in which n machines
are each given a local d-dimensional vector xv∈Rd, and must cooperate to estimate
the mean of their inputs μ=1n∑nv=1xv, while minimizing total communication cost.
DME is a fundamental construct in distributed machine learning, and there has
been considerable work on variants of this problem, especially in the context
of distributed variance reduction for stochastic gradients in parallel SGD. Previous
work typically assumes an upper bound on the norm of the input vectors, and achieves
an error bound in terms of this norm. However, in many real applications, the
input vectors are concentrated around the correct output μ, but μ itself has large
norm. In such cases, previous output error bounds perform poorly. In this paper,
we show that output error bounds need not depend on input norm. We provide a method
of quantization which allows distributed mean estimation to be performed with
solution quality dependent only on the distance between inputs, not on input norm,
and show an analogous result for distributed variance reduction. The technique
is based on a new connection with lattice theory. We also provide lower bounds
showing that the communication to error trade-off of our algorithms is asymptotically
optimal. As the lattices achieving optimal bounds under l2-norm can be computationally
impractical, we also present an extension which leverages easy-to-use cubic lattices,
and is loose only up to a logarithmic factor ind. We show experimentally that
our method yields practical improvements for common applications, relative to
prior approaches.
article_processing_charge: No
arxiv: 1
author:
- first_name: Peter
full_name: Davies, Peter
id: 11396234-BB50-11E9-B24C-90FCE5697425
last_name: Davies
orcid: 0000-0002-5646-9524
- first_name: Vijaykrishna
full_name: Gurunanthan, Vijaykrishna
last_name: Gurunanthan
- first_name: 'Niusha '
full_name: 'Moshrefi, Niusha '
id: 4db776ff-ce15-11eb-96e3-bc2b90b01c16
last_name: Moshrefi
- first_name: Saleh
full_name: Ashkboos, Saleh
id: 0D0A9058-257B-11EA-A937-9341C3D8BC8A
last_name: Ashkboos
- first_name: Dan-Adrian
full_name: Alistarh, Dan-Adrian
id: 4A899BFC-F248-11E8-B48F-1D18A9856A87
last_name: Alistarh
orcid: 0000-0003-3650-940X
citation:
ama: 'Davies P, Gurunanthan V, Moshrefi N, Ashkboos S, Alistarh D-A. New bounds
for distributed mean estimation and variance reduction. In: 9th International
Conference on Learning Representations. ; 2021.'
apa: Davies, P., Gurunanthan, V., Moshrefi, N., Ashkboos, S., & Alistarh, D.-A.
(2021). New bounds for distributed mean estimation and variance reduction. In
9th International Conference on Learning Representations. Virtual.
chicago: Davies, Peter, Vijaykrishna Gurunanthan, Niusha Moshrefi, Saleh Ashkboos,
and Dan-Adrian Alistarh. “New Bounds for Distributed Mean Estimation and Variance
Reduction.” In 9th International Conference on Learning Representations,
2021.
ieee: P. Davies, V. Gurunanthan, N. Moshrefi, S. Ashkboos, and D.-A. Alistarh, “New
bounds for distributed mean estimation and variance reduction,” in 9th International
Conference on Learning Representations, Virtual, 2021.
ista: 'Davies P, Gurunanthan V, Moshrefi N, Ashkboos S, Alistarh D-A. 2021. New
bounds for distributed mean estimation and variance reduction. 9th International
Conference on Learning Representations. ICLR: International Conference on Learning
Representations.'
mla: Davies, Peter, et al. “New Bounds for Distributed Mean Estimation and Variance
Reduction.” 9th International Conference on Learning Representations, 2021.
short: P. Davies, V. Gurunanthan, N. Moshrefi, S. Ashkboos, D.-A. Alistarh, in:,
9th International Conference on Learning Representations, 2021.
conference:
end_date: 2021-05-07
location: Virtual
name: ' ICLR: International Conference on Learning Representations'
start_date: 2021-05-03
date_created: 2021-06-10T19:46:08Z
date_published: 2021-05-01T00:00:00Z
date_updated: 2023-02-23T14:00:40Z
day: '01'
department:
- _id: DaAl
ec_funded: 1
external_id:
arxiv:
- '2002.09268'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://openreview.net/pdf?id=t86MwoUCCNe
month: '05'
oa: 1
oa_version: Published Version
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
publication: 9th International Conference on Learning Representations
publication_status: published
quality_controlled: '1'
status: public
title: New bounds for distributed mean estimation and variance reduction
type: conference
user_id: D865714E-FA4E-11E9-B85B-F5C5E5697425
year: '2021'
...
---
_id: '9547'
abstract:
- lang: eng
text: With the wider availability of full-color 3D printers, color-accurate 3D-print
preparation has received increased attention. A key challenge lies in the inherent
translucency of commonly used print materials that blurs out details of the color
texture. Previous work tries to compensate for these scattering effects through
strategic assignment of colored primary materials to printer voxels. To date,
the highest-quality approach uses iterative optimization that relies on computationally
expensive Monte Carlo light transport simulation to predict the surface appearance
from subsurface scattering within a given print material distribution; that optimization,
however, takes in the order of days on a single machine. In our work, we dramatically
speed up the process by replacing the light transport simulation with a data-driven
approach. Leveraging a deep neural network to predict the scattering within a
highly heterogeneous medium, our method performs around two orders of magnitude
faster than Monte Carlo rendering while yielding optimization results of similar
quality level. The network is based on an established method from atmospheric
cloud rendering, adapted to our domain and extended by a physically motivated
weight sharing scheme that substantially reduces the network size. We analyze
its performance in an end-to-end print preparation pipeline and compare quality
and runtime to alternative approaches, and demonstrate its generalization to unseen
geometry and material values. This for the first time enables full heterogenous
material optimization for 3D-print preparation within time frames in the order
of the actual printing time.
acknowledgement: We thank Sebastian Cucerca for processing and capturing the phys-cal
printouts. This work was supported by the Charles University grant SVV-260588 and
Czech Science Foundation grant 19-07626S. This project has received funding from
the European Union’s Horizon 2020 research and innovation programme, under the Marie
Skłodowska Curie grant agreements No 642841 (DISTRO) and No765911 (RealVision),
and under the European Research Council grant agreement No 715767 (MATERIALIZABLE).
article_processing_charge: No
article_type: original
author:
- first_name: Tobias
full_name: Rittig, Tobias
last_name: Rittig
- first_name: Denis
full_name: Sumin, Denis
last_name: Sumin
- first_name: Vahid
full_name: Babaei, Vahid
last_name: Babaei
- first_name: Piotr
full_name: Didyk, Piotr
last_name: Didyk
- first_name: Alexey
full_name: Voloboy, Alexey
last_name: Voloboy
- first_name: Alexander
full_name: Wilkie, Alexander
last_name: Wilkie
- first_name: Bernd
full_name: Bickel, Bernd
id: 49876194-F248-11E8-B48F-1D18A9856A87
last_name: Bickel
orcid: 0000-0001-6511-9385
- first_name: Karol
full_name: Myszkowski, Karol
last_name: Myszkowski
- first_name: Tim
full_name: Weyrich, Tim
last_name: Weyrich
- first_name: Jaroslav
full_name: Křivánek, Jaroslav
last_name: Křivánek
citation:
ama: Rittig T, Sumin D, Babaei V, et al. Neural acceleration of scattering-aware
color 3D printing. Computer Graphics Forum. 2021;40(2):205-219. doi:10.1111/cgf.142626
apa: Rittig, T., Sumin, D., Babaei, V., Didyk, P., Voloboy, A., Wilkie, A., … Křivánek,
J. (2021). Neural acceleration of scattering-aware color 3D printing. Computer
Graphics Forum. Wiley. https://doi.org/10.1111/cgf.142626
chicago: Rittig, Tobias, Denis Sumin, Vahid Babaei, Piotr Didyk, Alexey Voloboy,
Alexander Wilkie, Bernd Bickel, Karol Myszkowski, Tim Weyrich, and Jaroslav Křivánek.
“Neural Acceleration of Scattering-Aware Color 3D Printing.” Computer Graphics
Forum. Wiley, 2021. https://doi.org/10.1111/cgf.142626.
ieee: T. Rittig et al., “Neural acceleration of scattering-aware color 3D
printing,” Computer Graphics Forum, vol. 40, no. 2. Wiley, pp. 205–219,
2021.
ista: Rittig T, Sumin D, Babaei V, Didyk P, Voloboy A, Wilkie A, Bickel B, Myszkowski
K, Weyrich T, Křivánek J. 2021. Neural acceleration of scattering-aware color
3D printing. Computer Graphics Forum. 40(2), 205–219.
mla: Rittig, Tobias, et al. “Neural Acceleration of Scattering-Aware Color 3D Printing.”
Computer Graphics Forum, vol. 40, no. 2, Wiley, 2021, pp. 205–19, doi:10.1111/cgf.142626.
short: T. Rittig, D. Sumin, V. Babaei, P. Didyk, A. Voloboy, A. Wilkie, B. Bickel,
K. Myszkowski, T. Weyrich, J. Křivánek, Computer Graphics Forum 40 (2021) 205–219.
date_created: 2021-06-13T22:01:32Z
date_published: 2021-05-01T00:00:00Z
date_updated: 2023-08-14T08:01:50Z
day: '01'
ddc:
- '004'
department:
- _id: BeBi
doi: 10.1111/cgf.142626
ec_funded: 1
external_id:
isi:
- '000657959600017'
file:
- access_level: open_access
checksum: 33271724215f54a75c39d2ed40f2c502
content_type: application/pdf
creator: bbickel
date_created: 2021-10-11T12:06:50Z
date_updated: 2021-10-11T12:06:50Z
file_id: '10120'
file_name: ScatteringAwareColor3DPrinting_authorVersion.pdf
file_size: 26026501
relation: main_file
success: 1
file_date_updated: 2021-10-11T12:06:50Z
has_accepted_license: '1'
intvolume: ' 40'
isi: 1
issue: '2'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Submitted Version
page: 205-219
project:
- _id: 2508E324-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '642841'
name: Distributed 3D Object Design
- _id: 24F9549A-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '715767'
name: 'MATERIALIZABLE: Intelligent fabrication-oriented Computational Design and
Modeling'
publication: Computer Graphics Forum
publication_identifier:
eissn:
- 1467-8659
issn:
- 0167-7055
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Neural acceleration of scattering-aware color 3D printing
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 40
year: '2021'
...
---
_id: '9548'
abstract:
- lang: eng
text: 'We extend the notion of the minimal volume ellipsoid containing a convex
body in Rd to the setting of logarithmically concave functions. We consider a
vast class of logarithmically concave functions whose superlevel sets are concentric
ellipsoids. For a fixed function from this class, we consider the set of all its
“affine” positions. For any log-concave function f on Rd, we consider functions
belonging to this set of “affine” positions, and find the one with the minimal
integral under the condition that it is pointwise greater than or equal to f.
We study the properties of existence and uniqueness of the solution to this problem.
For any s∈[0,+∞), we consider the construction dual to the recently defined John
s-function (Ivanov and Naszódi in Functional John ellipsoids. arXiv preprint:
arXiv:2006.09934, 2020). We prove that such a construction determines a unique
function and call it the Löwner s-function of f. We study the Löwner s-functions
as s tends to zero and to infinity. Finally, extending the notion of the outer
volume ratio, we define the outer integral ratio of a log-concave function and
give an asymptotically tight bound on it.'
acknowledgement: The authors acknowledge the support of the grant of the Russian Government
N 075-15-2019-1926.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Grigory
full_name: Ivanov, Grigory
id: 87744F66-5C6F-11EA-AFE0-D16B3DDC885E
last_name: Ivanov
- first_name: Igor
full_name: Tsiutsiurupa, Igor
last_name: Tsiutsiurupa
citation:
ama: Ivanov G, Tsiutsiurupa I. Functional Löwner ellipsoids. Journal of Geometric
Analysis. 2021;31:11493-11528. doi:10.1007/s12220-021-00691-4
apa: Ivanov, G., & Tsiutsiurupa, I. (2021). Functional Löwner ellipsoids. Journal
of Geometric Analysis. Springer. https://doi.org/10.1007/s12220-021-00691-4
chicago: Ivanov, Grigory, and Igor Tsiutsiurupa. “Functional Löwner Ellipsoids.”
Journal of Geometric Analysis. Springer, 2021. https://doi.org/10.1007/s12220-021-00691-4.
ieee: G. Ivanov and I. Tsiutsiurupa, “Functional Löwner ellipsoids,” Journal
of Geometric Analysis, vol. 31. Springer, pp. 11493–11528, 2021.
ista: Ivanov G, Tsiutsiurupa I. 2021. Functional Löwner ellipsoids. Journal of Geometric
Analysis. 31, 11493–11528.
mla: Ivanov, Grigory, and Igor Tsiutsiurupa. “Functional Löwner Ellipsoids.” Journal
of Geometric Analysis, vol. 31, Springer, 2021, pp. 11493–528, doi:10.1007/s12220-021-00691-4.
short: G. Ivanov, I. Tsiutsiurupa, Journal of Geometric Analysis 31 (2021) 11493–11528.
date_created: 2021-06-13T22:01:32Z
date_published: 2021-05-31T00:00:00Z
date_updated: 2023-08-08T14:04:49Z
day: '31'
department:
- _id: UlWa
doi: 10.1007/s12220-021-00691-4
external_id:
arxiv:
- '2008.09543'
isi:
- '000656507500001'
intvolume: ' 31'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/2008.09543
month: '05'
oa: 1
oa_version: Preprint
page: 11493-11528
publication: Journal of Geometric Analysis
publication_identifier:
eissn:
- 1559-002X
issn:
- 1050-6926
publication_status: published
publisher: Springer
quality_controlled: '1'
scopus_import: '1'
status: public
title: Functional Löwner ellipsoids
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 31
year: '2021'
...
---
_id: '9549'
abstract:
- lang: eng
text: 'AMPA receptors (AMPARs) mediate the majority of excitatory transmission in
the brain and enable the synaptic plasticity that underlies learning1. A diverse
array of AMPAR signalling complexes are established by receptor auxiliary subunits,
which associate with the AMPAR in various combinations to modulate trafficking,
gating and synaptic strength2. However, their mechanisms of action are poorly
understood. Here we determine cryo-electron microscopy structures of the heteromeric
GluA1–GluA2 receptor assembled with both TARP-γ8 and CNIH2, the predominant AMPAR
complex in the forebrain, in both resting and active states. Two TARP-γ8 and two
CNIH2 subunits insert at distinct sites beneath the ligand-binding domains of
the receptor, with site-specific lipids shaping each interaction and affecting
the gating regulation of the AMPARs. Activation of the receptor leads to asymmetry
between GluA1 and GluA2 along the ion conduction path and an outward expansion
of the channel triggers counter-rotations of both auxiliary subunit pairs, promoting
the active-state conformation. In addition, both TARP-γ8 and CNIH2 pivot towards
the pore exit upon activation, extending their reach for cytoplasmic receptor
elements. CNIH2 achieves this through its uniquely extended M2 helix, which has
transformed this endoplasmic reticulum-export factor into a powerful AMPAR modulator
that is capable of providing hippocampal pyramidal neurons with their integrative
synaptic properties. '
acknowledgement: We thank members of the Greger laboratory, B. Herguedas, J. Krieger
and J.-N. Dohrke for comments on the manuscript; J. Krieger and J.-N. Dohrke for
discussion, J. Krieger for help with the normal mode analysis, B. Köhegyi for help
with cryo-EM imaging, V. Chang and K. Suzuki for helping to generate the CNIH2-1D4-HA
stable cell line, M. Carvalho for assistance at early stages of this project, the
LMB scientific computing and the cryo-EM facility for support, P. Emsley for help
with model building, T. Nakane for helpful comments with RELION 3.1 and R. Warshamanage
for helping with EMDA cryo-EM-map processing. We acknowledge the Diamond Light Source
for access and support of the Cryo-EM facilities at the UK national electron bio10
imaging centre (eBIC), proposal EM17434, funded by the Wellcome Trust, MRC and BBSRC.
This work was supported by grants from the Medical Research Council, as part of
United Kingdom Research and Innovation (also known as UK Research and Innovation)
(MC_U105174197) and BBSRC (BB/N002113/1) to I.H.G.
article_processing_charge: No
article_type: original
author:
- first_name: Danyang
full_name: Zhang, Danyang
last_name: Zhang
- first_name: Jake
full_name: Watson, Jake
id: 63836096-4690-11EA-BD4E-32803DDC885E
last_name: Watson
orcid: 0000-0002-8698-3823
- first_name: Peter M.
full_name: Matthews, Peter M.
last_name: Matthews
- first_name: Ondrej
full_name: Cais, Ondrej
last_name: Cais
- first_name: Ingo H.
full_name: Greger, Ingo H.
last_name: Greger
citation:
ama: Zhang D, Watson J, Matthews PM, Cais O, Greger IH. Gating and modulation of
a hetero-octameric AMPA glutamate receptor. Nature. 2021;594:454-458. doi:10.1038/s41586-021-03613-0
apa: Zhang, D., Watson, J., Matthews, P. M., Cais, O., & Greger, I. H. (2021).
Gating and modulation of a hetero-octameric AMPA glutamate receptor. Nature.
Springer Nature. https://doi.org/10.1038/s41586-021-03613-0
chicago: Zhang, Danyang, Jake Watson, Peter M. Matthews, Ondrej Cais, and Ingo H.
Greger. “Gating and Modulation of a Hetero-Octameric AMPA Glutamate Receptor.”
Nature. Springer Nature, 2021. https://doi.org/10.1038/s41586-021-03613-0.
ieee: D. Zhang, J. Watson, P. M. Matthews, O. Cais, and I. H. Greger, “Gating and
modulation of a hetero-octameric AMPA glutamate receptor,” Nature, vol.
594. Springer Nature, pp. 454–458, 2021.
ista: Zhang D, Watson J, Matthews PM, Cais O, Greger IH. 2021. Gating and modulation
of a hetero-octameric AMPA glutamate receptor. Nature. 594, 454–458.
mla: Zhang, Danyang, et al. “Gating and Modulation of a Hetero-Octameric AMPA Glutamate
Receptor.” Nature, vol. 594, Springer Nature, 2021, pp. 454–58, doi:10.1038/s41586-021-03613-0.
short: D. Zhang, J. Watson, P.M. Matthews, O. Cais, I.H. Greger, Nature 594 (2021)
454–458.
date_created: 2021-06-13T22:01:33Z
date_published: 2021-06-02T00:00:00Z
date_updated: 2023-08-08T13:59:51Z
day: '02'
department:
- _id: PeJo
doi: 10.1038/s41586-021-03613-0
external_id:
isi:
- '000657238100003'
pmid:
- '34079129'
intvolume: ' 594'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1038/s41586-021-03613-0
month: '06'
oa: 1
oa_version: Published Version
page: 454-458
pmid: 1
publication: Nature
publication_identifier:
eissn:
- 1476-4687
issn:
- 0028-0836
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Gating and modulation of a hetero-octameric AMPA glutamate receptor
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 594
year: '2021'
...
---
_id: '9550'
abstract:
- lang: eng
text: 'We prove that the energy of any eigenvector of a sum of several independent
large Wigner matrices is equally distributed among these matrices with very high
precision. This shows a particularly strong microcanonical form of the equipartition
principle for quantum systems whose components are modelled by Wigner matrices. '
acknowledgement: The first author is supported in part by Hong Kong RGC Grant GRF
16301519 and NSFC 11871425. The second author is supported in part by ERC Advanced
Grant RANMAT 338804. The third author is supported in part by Swedish Research Council
Grant VR-2017-05195 and the Knut and Alice Wallenberg Foundation
article_number: e44
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Zhigang
full_name: Bao, Zhigang
id: 442E6A6C-F248-11E8-B48F-1D18A9856A87
last_name: Bao
orcid: 0000-0003-3036-1475
- first_name: László
full_name: Erdös, László
id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
last_name: Erdös
orcid: 0000-0001-5366-9603
- first_name: Kevin
full_name: Schnelli, Kevin
id: 434AD0AE-F248-11E8-B48F-1D18A9856A87
last_name: Schnelli
orcid: 0000-0003-0954-3231
citation:
ama: Bao Z, Erdös L, Schnelli K. Equipartition principle for Wigner matrices. Forum
of Mathematics, Sigma. 2021;9. doi:10.1017/fms.2021.38
apa: Bao, Z., Erdös, L., & Schnelli, K. (2021). Equipartition principle for
Wigner matrices. Forum of Mathematics, Sigma. Cambridge University Press.
https://doi.org/10.1017/fms.2021.38
chicago: Bao, Zhigang, László Erdös, and Kevin Schnelli. “Equipartition Principle
for Wigner Matrices.” Forum of Mathematics, Sigma. Cambridge University
Press, 2021. https://doi.org/10.1017/fms.2021.38.
ieee: Z. Bao, L. Erdös, and K. Schnelli, “Equipartition principle for Wigner matrices,”
Forum of Mathematics, Sigma, vol. 9. Cambridge University Press, 2021.
ista: Bao Z, Erdös L, Schnelli K. 2021. Equipartition principle for Wigner matrices.
Forum of Mathematics, Sigma. 9, e44.
mla: Bao, Zhigang, et al. “Equipartition Principle for Wigner Matrices.” Forum
of Mathematics, Sigma, vol. 9, e44, Cambridge University Press, 2021, doi:10.1017/fms.2021.38.
short: Z. Bao, L. Erdös, K. Schnelli, Forum of Mathematics, Sigma 9 (2021).
date_created: 2021-06-13T22:01:33Z
date_published: 2021-05-27T00:00:00Z
date_updated: 2023-08-08T14:03:40Z
day: '27'
ddc:
- '510'
department:
- _id: LaEr
doi: 10.1017/fms.2021.38
ec_funded: 1
external_id:
arxiv:
- '2008.07061'
isi:
- '000654960800001'
file:
- access_level: open_access
checksum: 47c986578de132200d41e6d391905519
content_type: application/pdf
creator: cziletti
date_created: 2021-06-15T14:40:45Z
date_updated: 2021-06-15T14:40:45Z
file_id: '9555'
file_name: 2021_ForumMath_Bao.pdf
file_size: 483458
relation: main_file
success: 1
file_date_updated: 2021-06-15T14:40:45Z
has_accepted_license: '1'
intvolume: ' 9'
isi: 1
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
project:
- _id: 258DCDE6-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '338804'
name: Random matrices, universality and disordered quantum systems
publication: Forum of Mathematics, Sigma
publication_identifier:
eissn:
- '20505094'
publication_status: published
publisher: Cambridge University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Equipartition principle for Wigner matrices
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 9
year: '2021'
...
---
_id: '9558'
abstract:
- lang: eng
text: "We show that turbulent dynamics that arise in simulations of the three-dimensional
Navier--Stokes equations in a triply-periodic domain under sinusoidal forcing
can be described as transient visits to the neighborhoods of unstable time-periodic
solutions. Based on this description, we reduce the original system with more
than 10^5 degrees of freedom to a 17-node Markov chain where each node corresponds
to the neighborhood of a periodic orbit. The model accurately reproduces long-term
averages of the system's observables as weighted sums over the periodic orbits.\r\n"
acknowledged_ssus:
- _id: ScienComp
acknowledgement: "We thank the referees for improving this Letter with their comments.
We acknowledge stimulating discussions with\r\nH. Edelsbrunner. This work was supported
by Grant No. 662960 from the Simons Foundation (B. H.). The numerical calculations
were performed at TUBITAK ULAKBIM High Performance and Grid Computing Center (TRUBA
resources) and IST Austria High Performance Computing cluster."
article_number: '244502'
article_processing_charge: No
article_type: letter_note
arxiv: 1
author:
- first_name: Gökhan
full_name: Yalniz, Gökhan
id: 66E74FA2-D8BF-11E9-8249-8DE2E5697425
last_name: Yalniz
orcid: 0000-0002-8490-9312
- first_name: Björn
full_name: Hof, Björn
id: 3A374330-F248-11E8-B48F-1D18A9856A87
last_name: Hof
orcid: 0000-0003-2057-2754
- first_name: Nazmi B
full_name: Budanur, Nazmi B
id: 3EA1010E-F248-11E8-B48F-1D18A9856A87
last_name: Budanur
orcid: 0000-0003-0423-5010
citation:
ama: Yalniz G, Hof B, Budanur NB. Coarse graining the state space of a turbulent
flow using periodic orbits. Physical Review Letters. 2021;126(24). doi:10.1103/PhysRevLett.126.244502
apa: Yalniz, G., Hof, B., & Budanur, N. B. (2021). Coarse graining the state
space of a turbulent flow using periodic orbits. Physical Review Letters.
American Physical Society. https://doi.org/10.1103/PhysRevLett.126.244502
chicago: Yalniz, Gökhan, Björn Hof, and Nazmi B Budanur. “Coarse Graining the State
Space of a Turbulent Flow Using Periodic Orbits.” Physical Review Letters.
American Physical Society, 2021. https://doi.org/10.1103/PhysRevLett.126.244502.
ieee: G. Yalniz, B. Hof, and N. B. Budanur, “Coarse graining the state space of
a turbulent flow using periodic orbits,” Physical Review Letters, vol.
126, no. 24. American Physical Society, 2021.
ista: Yalniz G, Hof B, Budanur NB. 2021. Coarse graining the state space of a turbulent
flow using periodic orbits. Physical Review Letters. 126(24), 244502.
mla: Yalniz, Gökhan, et al. “Coarse Graining the State Space of a Turbulent Flow
Using Periodic Orbits.” Physical Review Letters, vol. 126, no. 24, 244502,
American Physical Society, 2021, doi:10.1103/PhysRevLett.126.244502.
short: G. Yalniz, B. Hof, N.B. Budanur, Physical Review Letters 126 (2021).
date_created: 2021-06-16T15:45:36Z
date_published: 2021-06-18T00:00:00Z
date_updated: 2023-08-08T14:08:36Z
day: '18'
department:
- _id: GradSch
- _id: BjHo
doi: 10.1103/PhysRevLett.126.244502
external_id:
arxiv:
- '2007.02584'
isi:
- '000663310100008'
intvolume: ' 126'
isi: 1
issue: '24'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/2007.02584
month: '06'
oa: 1
oa_version: Preprint
project:
- _id: 238598C6-32DE-11EA-91FC-C7463DDC885E
grant_number: '662960'
name: 'Revisiting the Turbulence Problem Using Statistical Mechanics: Experimental
Studies on Transitional and Turbulent Flows'
publication: Physical Review Letters
publication_identifier:
eissn:
- 1079-7114
issn:
- 0031-9007
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
related_material:
link:
- description: News on IST Homepage
relation: press_release
url: https://ist.ac.at/en/news/turbulent-flow-simplified/
status: public
title: Coarse graining the state space of a turbulent flow using periodic orbits
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 126
year: '2021'
...
---
_id: '9562'
abstract:
- lang: eng
text: Left-right asymmetries can be considered a fundamental organizational principle
of the vertebrate central nervous system. The hippocampal CA3-CA1 pyramidal cell
synaptic connection shows an input-side dependent asymmetry where the hemispheric
location of the presynaptic CA3 neuron determines the synaptic properties. Left-input
synapses terminating on apical dendrites in stratum radiatum have a higher density
of NMDA receptor subunit GluN2B, a lower density of AMPA receptor subunit GluA1
and smaller areas with less often perforated PSDs. On the other hand, left-input
synapses terminating on basal dendrites in stratum oriens have lower GluN2B densities
than right-input ones. Apical and basal synapses further employ different signaling
pathways involved in LTP. SDS-digested freeze-fracture replica labeling can visualize
synaptic membrane proteins with high sensitivity and resolution, and has been
used to reveal the asymmetry at the electron microscopic level. However, it requires
time-consuming manual demarcation of the synaptic surface for quantitative measurements.
To facilitate the analysis of replica labeling, I first developed a software named
Darea, which utilizes deep-learning to automatize this demarcation. With Darea
I characterized the synaptic distribution of NMDA and AMPA receptors as well as
the voltage-gated Ca2+ channels in CA1 stratum radiatum and oriens. Second, I
explored the role of GluN2B and its carboxy-terminus in the establishment of input-side
dependent hippocampal asymmetry. In conditional knock-out mice lacking GluN2B
expression in CA1 and GluN2B-2A swap mice, where GluN2B carboxy-terminus was exchanged
to that of GluN2A, no significant asymmetries of GluN2B, GluA1 and PSD area were
detected. We further discovered a previously unknown functional asymmetry of GluN2A,
which was also lost in the swap mouse. These results demonstrate that GluN2B carboxy-terminus
plays a critical role in normal formation of input-side dependent asymmetry.
acknowledged_ssus:
- _id: EM-Fac
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: David
full_name: Kleindienst, David
id: 42E121A4-F248-11E8-B48F-1D18A9856A87
last_name: Kleindienst
citation:
ama: 'Kleindienst D. 2B or not 2B: Hippocampal asymmetries mediated by NMDA receptor
subunit GluN2B C-terminus and high-throughput image analysis by Deep-Learning.
2021. doi:10.15479/at:ista:9562'
apa: 'Kleindienst, D. (2021). 2B or not 2B: Hippocampal asymmetries mediated
by NMDA receptor subunit GluN2B C-terminus and high-throughput image analysis
by Deep-Learning. Institute of Science and Technology Austria. https://doi.org/10.15479/at:ista:9562'
chicago: 'Kleindienst, David. “2B or Not 2B: Hippocampal Asymmetries Mediated by
NMDA Receptor Subunit GluN2B C-Terminus and High-Throughput Image Analysis by
Deep-Learning.” Institute of Science and Technology Austria, 2021. https://doi.org/10.15479/at:ista:9562.'
ieee: 'D. Kleindienst, “2B or not 2B: Hippocampal asymmetries mediated by NMDA receptor
subunit GluN2B C-terminus and high-throughput image analysis by Deep-Learning,”
Institute of Science and Technology Austria, 2021.'
ista: 'Kleindienst D. 2021. 2B or not 2B: Hippocampal asymmetries mediated by NMDA
receptor subunit GluN2B C-terminus and high-throughput image analysis by Deep-Learning.
Institute of Science and Technology Austria.'
mla: 'Kleindienst, David. 2B or Not 2B: Hippocampal Asymmetries Mediated by NMDA
Receptor Subunit GluN2B C-Terminus and High-Throughput Image Analysis by Deep-Learning.
Institute of Science and Technology Austria, 2021, doi:10.15479/at:ista:9562.'
short: 'D. Kleindienst, 2B or Not 2B: Hippocampal Asymmetries Mediated by NMDA Receptor
Subunit GluN2B C-Terminus and High-Throughput Image Analysis by Deep-Learning,
Institute of Science and Technology Austria, 2021.'
date_created: 2021-06-17T14:10:47Z
date_published: 2021-06-01T00:00:00Z
date_updated: 2023-09-11T12:55:53Z
day: '01'
ddc:
- '570'
degree_awarded: PhD
department:
- _id: GradSch
- _id: RySh
doi: 10.15479/at:ista:9562
file:
- access_level: open_access
checksum: 659df5518db495f679cb1df9e9bd1d94
content_type: application/pdf
creator: dkleindienst
date_created: 2021-06-17T14:03:14Z
date_updated: 2022-07-02T22:30:04Z
embargo: 2022-07-01
file_id: '9563'
file_name: Thesis.pdf
file_size: 77299142
relation: main_file
- access_level: closed
checksum: 3bcf63a2b19e5b6663be051bea332748
content_type: application/zip
creator: dkleindienst
date_created: 2021-06-17T14:04:30Z
date_updated: 2022-07-02T22:30:04Z
embargo_to: open_access
file_id: '9564'
file_name: Thesis_source.zip
file_size: 369804895
relation: source_file
file_date_updated: 2022-07-02T22:30:04Z
has_accepted_license: '1'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
page: '124'
publication_identifier:
issn:
- 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
record:
- id: '9756'
relation: part_of_dissertation
status: public
- id: '9437'
relation: part_of_dissertation
status: public
- id: '8532'
relation: part_of_dissertation
status: public
- id: '612'
relation: part_of_dissertation
status: public
status: public
supervisor:
- first_name: Ryuichi
full_name: Shigemoto, Ryuichi
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
title: '2B or not 2B: Hippocampal asymmetries mediated by NMDA receptor subunit GluN2B
C-terminus and high-throughput image analysis by Deep-Learning'
type: dissertation
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2021'
...