---
_id: '8993'
abstract:
- lang: eng
  text: N-1-naphthylphthalamic acid (NPA) is a key inhibitor of directional (polar)
    transport of the hormone auxin in plants. For decades, it has been a pivotal tool
    in elucidating the unique polar auxin transport-based processes underlying plant
    growth and development. Its exact mode of action has long been sought after and
    is still being debated, with prevailing mechanistic schemes describing only indirect
    connections between NPA and the main transporters responsible for directional
    transport, namely PIN auxin exporters. Here we present data supporting a model
    in which NPA associates with PINs in a more direct manner than hitherto postulated.
    We show that NPA inhibits PIN activity in a heterologous oocyte system and that
    expression of NPA-sensitive PINs in plant, yeast, and oocyte membranes leads to
    specific saturable NPA binding. We thus propose that PINs are a bona fide NPA
    target. This offers a straightforward molecular basis for NPA inhibition of PIN-dependent
    auxin transport and a logical parsimonious explanation for the known physiological
    effects of NPA on plant growth, as well as an alternative hypothesis to interpret
    past and future results. We also introduce PIN dimerization and describe an effect
    of NPA on this, suggesting that NPA binding could be exploited to gain insights
    into structural aspects of PINs related to their transport mechanism.
acknowledgement: "This work was supported by Austrian Science Fund Grant FWF P21533-B20
  (to L.A.); German Research Foundation Grant DFG HA3468/6-1 (to U.Z.H.); and European
  Research Council Grant 742985 (to J.F.). We thank Herta Steinkellner and Alexandra
  Castilho for N. benthamiana plants, Fabian Nagelreiter for statistical advice, Lanassa
  Bassukas for help with [ɣ32P]-\r\nATP assays, and Josef Penninger for providing
  access to mass spectrometry instruments at the Vienna BioCenter Core Facilities.
  We thank PNAS reviewers for the many comments and suggestions that helped to improve
  this manuscript."
article_number: e2020857118
article_processing_charge: No
article_type: original
author:
- first_name: Lindy
  full_name: Abas, Lindy
  last_name: Abas
- first_name: Martina
  full_name: Kolb, Martina
  last_name: Kolb
- first_name: Johannes
  full_name: Stadlmann, Johannes
  last_name: Stadlmann
- first_name: Dorina P.
  full_name: Janacek, Dorina P.
  last_name: Janacek
- first_name: Kristina
  full_name: Lukic, Kristina
  id: 2B04DB84-F248-11E8-B48F-1D18A9856A87
  last_name: Lukic
  orcid: 0000-0003-1581-881X
- first_name: Claus
  full_name: Schwechheimer, Claus
  last_name: Schwechheimer
- first_name: Leonid A
  full_name: Sazanov, Leonid A
  id: 338D39FE-F248-11E8-B48F-1D18A9856A87
  last_name: Sazanov
  orcid: 0000-0002-0977-7989
- first_name: Lukas
  full_name: Mach, Lukas
  last_name: Mach
- first_name: Jiří
  full_name: Friml, Jiří
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
- first_name: Ulrich Z.
  full_name: Hammes, Ulrich Z.
  last_name: Hammes
citation:
  ama: Abas L, Kolb M, Stadlmann J, et al. Naphthylphthalamic acid associates with
    and inhibits PIN auxin transporters. <i>PNAS</i>. 2021;118(1). doi:<a href="https://doi.org/10.1073/pnas.2020857118">10.1073/pnas.2020857118</a>
  apa: Abas, L., Kolb, M., Stadlmann, J., Janacek, D. P., Lukic, K., Schwechheimer,
    C., … Hammes, U. Z. (2021). Naphthylphthalamic acid associates with and inhibits
    PIN auxin transporters. <i>PNAS</i>. National Academy of Sciences. <a href="https://doi.org/10.1073/pnas.2020857118">https://doi.org/10.1073/pnas.2020857118</a>
  chicago: Abas, Lindy, Martina Kolb, Johannes Stadlmann, Dorina P. Janacek, Kristina
    Lukic, Claus Schwechheimer, Leonid A Sazanov, Lukas Mach, Jiří Friml, and Ulrich
    Z. Hammes. “Naphthylphthalamic Acid Associates with and Inhibits PIN Auxin Transporters.”
    <i>PNAS</i>. National Academy of Sciences, 2021. <a href="https://doi.org/10.1073/pnas.2020857118">https://doi.org/10.1073/pnas.2020857118</a>.
  ieee: L. Abas <i>et al.</i>, “Naphthylphthalamic acid associates with and inhibits
    PIN auxin transporters,” <i>PNAS</i>, vol. 118, no. 1. National Academy of Sciences,
    2021.
  ista: Abas L, Kolb M, Stadlmann J, Janacek DP, Lukic K, Schwechheimer C, Sazanov
    LA, Mach L, Friml J, Hammes UZ. 2021. Naphthylphthalamic acid associates with
    and inhibits PIN auxin transporters. PNAS. 118(1), e2020857118.
  mla: Abas, Lindy, et al. “Naphthylphthalamic Acid Associates with and Inhibits PIN
    Auxin Transporters.” <i>PNAS</i>, vol. 118, no. 1, e2020857118, National Academy
    of Sciences, 2021, doi:<a href="https://doi.org/10.1073/pnas.2020857118">10.1073/pnas.2020857118</a>.
  short: L. Abas, M. Kolb, J. Stadlmann, D.P. Janacek, K. Lukic, C. Schwechheimer,
    L.A. Sazanov, L. Mach, J. Friml, U.Z. Hammes, PNAS 118 (2021).
date_created: 2021-01-03T23:01:23Z
date_published: 2021-01-05T00:00:00Z
date_updated: 2023-08-07T13:29:23Z
day: '05'
department:
- _id: JiFr
- _id: LeSa
doi: 10.1073/pnas.2020857118
ec_funded: 1
external_id:
  isi:
  - '000607270100073'
  pmid:
  - '33443187'
intvolume: '       118'
isi: 1
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1073/pnas.2020857118
month: '01'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 261099A6-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '742985'
  name: Tracing Evolution of Auxin Transport and Polarity in Plants
publication: PNAS
publication_identifier:
  eissn:
  - '10916490'
  issn:
  - '00278424'
publication_status: published
publisher: National Academy of Sciences
quality_controlled: '1'
related_material:
  link:
  - relation: erratum
    url: https://doi.org/10.1073/pnas.2102232118
scopus_import: '1'
status: public
title: Naphthylphthalamic acid associates with and inhibits PIN auxin transporters
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 118
year: '2021'
...
---
_id: '8997'
abstract:
- lang: eng
  text: Phenomenological relations such as Ohm’s or Fourier’s law have a venerable
    history in physics but are still scarce in biology. This situation restrains predictive
    theory. Here, we build on bacterial “growth laws,” which capture physiological
    feedback between translation and cell growth, to construct a minimal biophysical
    model for the combined action of ribosome-targeting antibiotics. Our model predicts
    drug interactions like antagonism or synergy solely from responses to individual
    drugs. We provide analytical results for limiting cases, which agree well with
    numerical results. We systematically refine the model by including direct physical
    interactions of different antibiotics on the ribosome. In a limiting case, our
    model provides a mechanistic underpinning for recent predictions of higher-order
    interactions that were derived using entropy maximization. We further refine the
    model to include the effects of antibiotics that mimic starvation and the presence
    of resistance genes. We describe the impact of a starvation-mimicking antibiotic
    on drug interactions analytically and verify it experimentally. Our extended model
    suggests a change in the type of drug interaction that depends on the strength
    of resistance, which challenges established rescaling paradigms. We experimentally
    show that the presence of unregulated resistance genes can lead to altered drug
    interaction, which agrees with the prediction of the model. While minimal, the
    model is readily adaptable and opens the door to predicting interactions of second
    and higher-order in a broad range of biological systems.
acknowledgement: 'This work was supported in part by Tum stipend of Knafelj foundation
  (to B.K.), Austrian Science Fund (FWF) standalone grants P 27201-B22 (to T.B.) and
  P 28844(to G.T.), HFSP program Grant RGP0042/2013 (to T.B.), German Research Foundation
  (DFG) individual grant BO 3502/2-1 (to T.B.), and German Research Foundation (DFG)
  Collaborative Research Centre (SFB) 1310 (to T.B.). '
article_number: e1008529
article_processing_charge: Yes
article_type: original
author:
- first_name: Bor
  full_name: Kavcic, Bor
  id: 350F91D2-F248-11E8-B48F-1D18A9856A87
  last_name: Kavcic
  orcid: 0000-0001-6041-254X
- first_name: Gašper
  full_name: Tkačik, Gašper
  id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
  last_name: Tkačik
  orcid: 0000-0002-6699-1455
- first_name: Tobias
  full_name: Bollenbach, Tobias
  id: 3E6DB97A-F248-11E8-B48F-1D18A9856A87
  last_name: Bollenbach
  orcid: 0000-0003-4398-476X
citation:
  ama: Kavcic B, Tkačik G, Bollenbach MT. Minimal biophysical model of combined antibiotic
    action. <i>PLOS Computational Biology</i>. 2021;17. doi:<a href="https://doi.org/10.1371/journal.pcbi.1008529">10.1371/journal.pcbi.1008529</a>
  apa: Kavcic, B., Tkačik, G., &#38; Bollenbach, M. T. (2021). Minimal biophysical
    model of combined antibiotic action. <i>PLOS Computational Biology</i>. Public
    Library of Science. <a href="https://doi.org/10.1371/journal.pcbi.1008529">https://doi.org/10.1371/journal.pcbi.1008529</a>
  chicago: Kavcic, Bor, Gašper Tkačik, and Mark Tobias Bollenbach. “Minimal Biophysical
    Model of Combined Antibiotic Action.” <i>PLOS Computational Biology</i>. Public
    Library of Science, 2021. <a href="https://doi.org/10.1371/journal.pcbi.1008529">https://doi.org/10.1371/journal.pcbi.1008529</a>.
  ieee: B. Kavcic, G. Tkačik, and M. T. Bollenbach, “Minimal biophysical model of
    combined antibiotic action,” <i>PLOS Computational Biology</i>, vol. 17. Public
    Library of Science, 2021.
  ista: Kavcic B, Tkačik G, Bollenbach MT. 2021. Minimal biophysical model of combined
    antibiotic action. PLOS Computational Biology. 17, e1008529.
  mla: Kavcic, Bor, et al. “Minimal Biophysical Model of Combined Antibiotic Action.”
    <i>PLOS Computational Biology</i>, vol. 17, e1008529, Public Library of Science,
    2021, doi:<a href="https://doi.org/10.1371/journal.pcbi.1008529">10.1371/journal.pcbi.1008529</a>.
  short: B. Kavcic, G. Tkačik, M.T. Bollenbach, PLOS Computational Biology 17 (2021).
date_created: 2021-01-08T07:16:18Z
date_published: 2021-01-07T00:00:00Z
date_updated: 2024-02-21T12:41:41Z
day: '07'
ddc:
- '570'
department:
- _id: GaTk
doi: 10.1371/journal.pcbi.1008529
external_id:
  isi:
  - '000608045000010'
file:
- access_level: open_access
  checksum: e29f2b42651bef8e034781de8781ffac
  content_type: application/pdf
  creator: dernst
  date_created: 2021-02-04T12:30:48Z
  date_updated: 2021-02-04T12:30:48Z
  file_id: '9092'
  file_name: 2021_PlosComBio_Kavcic.pdf
  file_size: 3690053
  relation: main_file
  success: 1
file_date_updated: 2021-02-04T12:30:48Z
has_accepted_license: '1'
intvolume: '        17'
isi: 1
keyword:
- Modelling and Simulation
- Genetics
- Molecular Biology
- Antibiotics
- Drug interactions
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
project:
- _id: 25E9AF9E-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: P27201-B22
  name: Revealing the mechanisms underlying drug interactions
- _id: 254E9036-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: P28844-B27
  name: Biophysics of information processing in gene regulation
publication: PLOS Computational Biology
publication_identifier:
  issn:
  - 1553-7358
publication_status: published
publisher: Public Library of Science
quality_controlled: '1'
related_material:
  record:
  - id: '7673'
    relation: earlier_version
    status: public
  - id: '8930'
    relation: research_data
    status: public
status: public
title: Minimal biophysical model of combined antibiotic action
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 17
year: '2021'
...
---
_id: '8999'
abstract:
- lang: eng
  text: "In many basic shear flows, such as pipe, Couette, and channel flow, turbulence
    does not\r\narise from an instability of the laminar state, and both dynamical
    states co-exist. With decreasing flow speed (i.e., decreasing Reynolds number)
    the fraction of fluid in laminar motion increases while turbulence recedes and
    eventually the entire flow relaminarizes. The first step towards understanding
    the nature of this transition is to determine if the phase change is of either
    first or second order. In the former case, the turbulent fraction would drop discontinuously
    to zero as the Reynolds number decreases while in the latter the process would
    be continuous. For Couette flow, the flow between two parallel plates, earlier
    studies suggest a discontinuous scenario. In the present study we realize a Couette
    flow between two concentric cylinders which allows studies to be carried out in
    large aspect ratios and for extensive observation times. The presented measurements
    show that the transition in this circular Couette geometry is continuous suggesting
    that former studies were limited by finite size effects. A further characterization
    of this transition, in particular its relation to the directed percolation universality
    class, requires even larger system sizes than presently available. "
acknowledgement: "This research was funded by the Central Research Development Fund
  of the University of\r\nBremen grant number ZF04B /2019/FB04 Avila_Kerstin (“Independent
  Project for Postdocs”). Shreyas Jalikop is acknowledged for recording some of the
  lifetime measurements\r\n"
article_number: '58'
article_processing_charge: No
article_type: original
author:
- first_name: Kerstin
  full_name: Avila, Kerstin
  id: fcf74381-53e1-11eb-a6dc-b0e2acf78757
  last_name: Avila
- first_name: Björn
  full_name: Hof, Björn
  id: 3A374330-F248-11E8-B48F-1D18A9856A87
  last_name: Hof
  orcid: 0000-0003-2057-2754
citation:
  ama: Avila K, Hof B. Second-order phase transition in counter-rotating taylor-couette
    flow experiment. <i>Entropy</i>. 2021;23(1). doi:<a href="https://doi.org/10.3390/e23010058">10.3390/e23010058</a>
  apa: Avila, K., &#38; Hof, B. (2021). Second-order phase transition in counter-rotating
    taylor-couette flow experiment. <i>Entropy</i>. MDPI. <a href="https://doi.org/10.3390/e23010058">https://doi.org/10.3390/e23010058</a>
  chicago: Avila, Kerstin, and Björn Hof. “Second-Order Phase Transition in Counter-Rotating
    Taylor-Couette Flow Experiment.” <i>Entropy</i>. MDPI, 2021. <a href="https://doi.org/10.3390/e23010058">https://doi.org/10.3390/e23010058</a>.
  ieee: K. Avila and B. Hof, “Second-order phase transition in counter-rotating taylor-couette
    flow experiment,” <i>Entropy</i>, vol. 23, no. 1. MDPI, 2021.
  ista: Avila K, Hof B. 2021. Second-order phase transition in counter-rotating taylor-couette
    flow experiment. Entropy. 23(1), 58.
  mla: Avila, Kerstin, and Björn Hof. “Second-Order Phase Transition in Counter-Rotating
    Taylor-Couette Flow Experiment.” <i>Entropy</i>, vol. 23, no. 1, 58, MDPI, 2021,
    doi:<a href="https://doi.org/10.3390/e23010058">10.3390/e23010058</a>.
  short: K. Avila, B. Hof, Entropy 23 (2021).
date_created: 2021-01-10T23:01:17Z
date_published: 2021-01-01T00:00:00Z
date_updated: 2023-08-07T13:31:07Z
day: '01'
ddc:
- '530'
department:
- _id: BjHo
doi: 10.3390/e23010058
external_id:
  isi:
  - '000610135400001'
  pmid:
  - '33396499'
file:
- access_level: open_access
  checksum: 3ba3dd8b7eecff713b72c5e9ba30d626
  content_type: application/pdf
  creator: dernst
  date_created: 2021-01-11T07:50:32Z
  date_updated: 2021-01-11T07:50:32Z
  file_id: '9003'
  file_name: 2021_Entropy_Avila.pdf
  file_size: 9456389
  relation: main_file
  success: 1
file_date_updated: 2021-01-11T07:50:32Z
has_accepted_license: '1'
intvolume: '        23'
isi: 1
issue: '1'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
pmid: 1
publication: Entropy
publication_identifier:
  eissn:
  - 1099-4300
publication_status: published
publisher: MDPI
quality_controlled: '1'
scopus_import: '1'
status: public
title: Second-order phase transition in counter-rotating taylor-couette flow experiment
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 23
year: '2021'
...
---
_id: '9002'
abstract:
- lang: eng
  text: ' We prove that, for the binary erasure channel (BEC), the polar-coding paradigm
    gives rise to codes that not only approach the Shannon limit but do so under the
    best possible scaling of their block length as a function of the gap to capacity.
    This result exhibits the first known family of binary codes that attain both optimal
    scaling and quasi-linear complexity of encoding and decoding. Our proof is based
    on the construction and analysis of binary polar codes with large kernels. When
    communicating reliably at rates within ε>0 of capacity, the code length n often
    scales as O(1/εμ), where the constant μ is called the scaling exponent. It is
    known that the optimal scaling exponent is μ=2, and it is achieved by random linear
    codes. The scaling exponent of conventional polar codes (based on the 2×2 kernel)
    on the BEC is μ=3.63. This falls far short of the optimal scaling guaranteed by
    random codes. Our main contribution is a rigorous proof of the following result:
    for the BEC, there exist ℓ×ℓ binary kernels, such that polar codes constructed
    from these kernels achieve scaling exponent μ(ℓ) that tends to the optimal value
    of 2 as ℓ grows. We furthermore characterize precisely how large ℓ needs to be
    as a function of the gap between μ(ℓ) and 2. The resulting binary codes maintain
    the recursive structure of conventional polar codes, and thereby achieve construction
    complexity O(n) and encoding/decoding complexity O(nlogn).'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Arman
  full_name: Fazeli, Arman
  last_name: Fazeli
- first_name: Hamed
  full_name: Hassani, Hamed
  last_name: Hassani
- first_name: Marco
  full_name: Mondelli, Marco
  id: 27EB676C-8706-11E9-9510-7717E6697425
  last_name: Mondelli
  orcid: 0000-0002-3242-7020
- first_name: Alexander
  full_name: Vardy, Alexander
  last_name: Vardy
citation:
  ama: 'Fazeli A, Hassani H, Mondelli M, Vardy A. Binary linear codes with optimal
    scaling: Polar codes with large kernels. <i>IEEE Transactions on Information Theory</i>.
    2021;67(9):5693-5710. doi:<a href="https://doi.org/10.1109/TIT.2020.3038806">10.1109/TIT.2020.3038806</a>'
  apa: 'Fazeli, A., Hassani, H., Mondelli, M., &#38; Vardy, A. (2021). Binary linear
    codes with optimal scaling: Polar codes with large kernels. <i>IEEE Transactions
    on Information Theory</i>. IEEE. <a href="https://doi.org/10.1109/TIT.2020.3038806">https://doi.org/10.1109/TIT.2020.3038806</a>'
  chicago: 'Fazeli, Arman, Hamed Hassani, Marco Mondelli, and Alexander Vardy. “Binary
    Linear Codes with Optimal Scaling: Polar Codes with Large Kernels.” <i>IEEE Transactions
    on Information Theory</i>. IEEE, 2021. <a href="https://doi.org/10.1109/TIT.2020.3038806">https://doi.org/10.1109/TIT.2020.3038806</a>.'
  ieee: 'A. Fazeli, H. Hassani, M. Mondelli, and A. Vardy, “Binary linear codes with
    optimal scaling: Polar codes with large kernels,” <i>IEEE Transactions on Information
    Theory</i>, vol. 67, no. 9. IEEE, pp. 5693–5710, 2021.'
  ista: 'Fazeli A, Hassani H, Mondelli M, Vardy A. 2021. Binary linear codes with
    optimal scaling: Polar codes with large kernels. IEEE Transactions on Information
    Theory. 67(9), 5693–5710.'
  mla: 'Fazeli, Arman, et al. “Binary Linear Codes with Optimal Scaling: Polar Codes
    with Large Kernels.” <i>IEEE Transactions on Information Theory</i>, vol. 67,
    no. 9, IEEE, 2021, pp. 5693–710, doi:<a href="https://doi.org/10.1109/TIT.2020.3038806">10.1109/TIT.2020.3038806</a>.'
  short: A. Fazeli, H. Hassani, M. Mondelli, A. Vardy, IEEE Transactions on Information
    Theory 67 (2021) 5693–5710.
date_created: 2021-01-10T23:01:18Z
date_published: 2021-09-01T00:00:00Z
date_updated: 2024-03-07T12:18:50Z
day: '01'
department:
- _id: MaMo
doi: 10.1109/TIT.2020.3038806
external_id:
  arxiv:
  - '1711.01339'
intvolume: '        67'
issue: '9'
language:
- iso: eng
month: '09'
oa_version: Preprint
page: 5693-5710
publication: IEEE Transactions on Information Theory
publication_identifier:
  eissn:
  - 1557-9654
  issn:
  - 0018-9448
publication_status: published
publisher: IEEE
quality_controlled: '1'
related_material:
  record:
  - id: '6665'
    relation: earlier_version
    status: public
scopus_import: '1'
status: public
title: 'Binary linear codes with optimal scaling: Polar codes with large kernels'
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 67
year: '2021'
...
---
_id: '9005'
abstract:
- lang: eng
  text: Studies on the experimental realization of two-dimensional anyons in terms
    of quasiparticles have been restricted, so far, to only anyons on the plane. It
    is known, however, that the geometry and topology of space can have significant
    effects on quantum statistics for particles moving on it. Here, we have undertaken
    the first step toward realizing the emerging fractional statistics for particles
    restricted to move on the sphere instead of on the plane. We show that such a
    model arises naturally in the context of quantum impurity problems. In particular,
    we demonstrate a setup in which the lowest-energy spectrum of two linear bosonic
    or fermionic molecules immersed in a quantum many-particle environment can coincide
    with the anyonic spectrum on the sphere. This paves the way toward the experimental
    realization of anyons on the sphere using molecular impurities. Furthermore, since
    a change in the alignment of the molecules corresponds to the exchange of the
    particles on the sphere, such a realization reveals a novel type of exclusion
    principle for molecular impurities, which could also be of use as a powerful technique
    to measure the statistics parameter. Finally, our approach opens up a simple numerical
    route to investigate the spectra of many anyons on the sphere. Accordingly, we
    present the spectrum of two anyons on the sphere in the presence of a Dirac monopole
    field.
acknowledgement: "We are grateful to A. Ghazaryan for valuable discussions and also
  thank the anonymous referees for comments. D.L. acknowledges financial support from
  the G¨oran Gustafsson Foundation (grant no. 1804) and LMU Munich. M.L. gratefully
  acknowledges financial support\r\nby the European Research Council (ERC) under the
  European Union’s Horizon 2020 research and innovation programme (grant agreements
  No 801770)."
article_number: '015301'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Morris
  full_name: Brooks, Morris
  id: B7ECF9FC-AA38-11E9-AC9A-0930E6697425
  last_name: Brooks
  orcid: 0000-0002-6249-0928
- first_name: Mikhail
  full_name: Lemeshko, Mikhail
  id: 37CB05FA-F248-11E8-B48F-1D18A9856A87
  last_name: Lemeshko
  orcid: 0000-0002-6990-7802
- first_name: D.
  full_name: Lundholm, D.
  last_name: Lundholm
- first_name: Enderalp
  full_name: Yakaboylu, Enderalp
  id: 38CB71F6-F248-11E8-B48F-1D18A9856A87
  last_name: Yakaboylu
  orcid: 0000-0001-5973-0874
citation:
  ama: Brooks M, Lemeshko M, Lundholm D, Yakaboylu E. Molecular impurities as a realization
    of anyons on the two-sphere. <i>Physical Review Letters</i>. 2021;126(1). doi:<a
    href="https://doi.org/10.1103/PhysRevLett.126.015301">10.1103/PhysRevLett.126.015301</a>
  apa: Brooks, M., Lemeshko, M., Lundholm, D., &#38; Yakaboylu, E. (2021). Molecular
    impurities as a realization of anyons on the two-sphere. <i>Physical Review Letters</i>.
    American Physical Society. <a href="https://doi.org/10.1103/PhysRevLett.126.015301">https://doi.org/10.1103/PhysRevLett.126.015301</a>
  chicago: Brooks, Morris, Mikhail Lemeshko, D. Lundholm, and Enderalp Yakaboylu.
    “Molecular Impurities as a Realization of Anyons on the Two-Sphere.” <i>Physical
    Review Letters</i>. American Physical Society, 2021. <a href="https://doi.org/10.1103/PhysRevLett.126.015301">https://doi.org/10.1103/PhysRevLett.126.015301</a>.
  ieee: M. Brooks, M. Lemeshko, D. Lundholm, and E. Yakaboylu, “Molecular impurities
    as a realization of anyons on the two-sphere,” <i>Physical Review Letters</i>,
    vol. 126, no. 1. American Physical Society, 2021.
  ista: Brooks M, Lemeshko M, Lundholm D, Yakaboylu E. 2021. Molecular impurities
    as a realization of anyons on the two-sphere. Physical Review Letters. 126(1),
    015301.
  mla: Brooks, Morris, et al. “Molecular Impurities as a Realization of Anyons on
    the Two-Sphere.” <i>Physical Review Letters</i>, vol. 126, no. 1, 015301, American
    Physical Society, 2021, doi:<a href="https://doi.org/10.1103/PhysRevLett.126.015301">10.1103/PhysRevLett.126.015301</a>.
  short: M. Brooks, M. Lemeshko, D. Lundholm, E. Yakaboylu, Physical Review Letters
    126 (2021).
date_created: 2021-01-17T23:01:10Z
date_published: 2021-01-08T00:00:00Z
date_updated: 2023-08-07T13:32:10Z
day: '08'
department:
- _id: MiLe
- _id: RoSe
doi: 10.1103/PhysRevLett.126.015301
ec_funded: 1
external_id:
  arxiv:
  - '2009.05948'
  isi:
  - '000606325000003'
intvolume: '       126'
isi: 1
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/2009.05948
month: '01'
oa: 1
oa_version: Preprint
project:
- _id: 2688CF98-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '801770'
  name: 'Angulon: physics and applications of a new quasiparticle'
publication: Physical Review Letters
publication_identifier:
  eissn:
  - '10797114'
  issn:
  - '00319007'
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
related_material:
  link:
  - description: News on IST Homepage
    relation: press_release
    url: https://ist.ac.at/en/news/dancing-molecules-and-two-dimensional-particles/
  record:
  - id: '12390'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: Molecular impurities as a realization of anyons on the two-sphere
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 126
year: '2021'
...
---
_id: '9006'
abstract:
- lang: eng
  text: Cytoplasm is a gel-like crowded environment composed of various macromolecules,
    organelles, cytoskeletal networks, and cytosol. The structure of the cytoplasm
    is highly organized and heterogeneous due to the crowding of its constituents
    and their effective compartmentalization. In such an environment, the diffusive
    dynamics of the molecules are restricted, an effect that is further amplified
    by clustering and anchoring of molecules. Despite the crowded nature of the cytoplasm
    at the microscopic scale, large-scale reorganization of the cytoplasm is essential
    for important cellular functions, such as cell division and polarization. How
    such mesoscale reorganization of the cytoplasm is achieved, especially for large
    cells such as oocytes or syncytial tissues that can span hundreds of micrometers
    in size, is only beginning to be understood. In this review, we will discuss recent
    advances in elucidating the molecular, cellular, and biophysical mechanisms by
    which the cytoskeleton drives cytoplasmic reorganization across different scales,
    structures, and species.
acknowledgement: We would like to thank Justine Renno for illustrations and Edouard
  Hannezo and members of the Heisenberg group for their comments on previous versions
  of the manuscript.
article_processing_charge: No
article_type: original
author:
- first_name: Shayan
  full_name: Shamipour, Shayan
  id: 40B34FE2-F248-11E8-B48F-1D18A9856A87
  last_name: Shamipour
- first_name: Silvia
  full_name: Caballero Mancebo, Silvia
  id: 2F1E1758-F248-11E8-B48F-1D18A9856A87
  last_name: Caballero Mancebo
  orcid: 0000-0002-5223-3346
- first_name: Carl-Philipp J
  full_name: Heisenberg, Carl-Philipp J
  id: 39427864-F248-11E8-B48F-1D18A9856A87
  last_name: Heisenberg
  orcid: 0000-0002-0912-4566
citation:
  ama: Shamipour S, Caballero Mancebo S, Heisenberg C-PJ. Cytoplasm’s got moves. <i>Developmental
    Cell</i>. 2021;56(2):P213-226. doi:<a href="https://doi.org/10.1016/j.devcel.2020.12.002">10.1016/j.devcel.2020.12.002</a>
  apa: Shamipour, S., Caballero Mancebo, S., &#38; Heisenberg, C.-P. J. (2021). Cytoplasm’s
    got moves. <i>Developmental Cell</i>. Elsevier. <a href="https://doi.org/10.1016/j.devcel.2020.12.002">https://doi.org/10.1016/j.devcel.2020.12.002</a>
  chicago: Shamipour, Shayan, Silvia Caballero Mancebo, and Carl-Philipp J Heisenberg.
    “Cytoplasm’s Got Moves.” <i>Developmental Cell</i>. Elsevier, 2021. <a href="https://doi.org/10.1016/j.devcel.2020.12.002">https://doi.org/10.1016/j.devcel.2020.12.002</a>.
  ieee: S. Shamipour, S. Caballero Mancebo, and C.-P. J. Heisenberg, “Cytoplasm’s
    got moves,” <i>Developmental Cell</i>, vol. 56, no. 2. Elsevier, pp. P213-226,
    2021.
  ista: Shamipour S, Caballero Mancebo S, Heisenberg C-PJ. 2021. Cytoplasm’s got moves.
    Developmental Cell. 56(2), P213-226.
  mla: Shamipour, Shayan, et al. “Cytoplasm’s Got Moves.” <i>Developmental Cell</i>,
    vol. 56, no. 2, Elsevier, 2021, pp. P213-226, doi:<a href="https://doi.org/10.1016/j.devcel.2020.12.002">10.1016/j.devcel.2020.12.002</a>.
  short: S. Shamipour, S. Caballero Mancebo, C.-P.J. Heisenberg, Developmental Cell
    56 (2021) P213-226.
date_created: 2021-01-17T23:01:10Z
date_published: 2021-01-25T00:00:00Z
date_updated: 2024-03-25T23:30:10Z
day: '25'
department:
- _id: CaHe
doi: 10.1016/j.devcel.2020.12.002
external_id:
  isi:
  - '000613273900009'
  pmid:
  - '33321104'
intvolume: '        56'
isi: 1
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1016/j.devcel.2020.12.002
month: '01'
oa: 1
oa_version: Published Version
page: P213-226
pmid: 1
publication: Developmental Cell
publication_identifier:
  eissn:
  - '18781551'
  issn:
  - '15345807'
publication_status: published
publisher: Elsevier
quality_controlled: '1'
related_material:
  record:
  - id: '9623'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: Cytoplasm's got moves
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 56
year: '2021'
...
---
_id: '9009'
abstract:
- lang: eng
  text: Recent advancements in live cell imaging technologies have identified the
    phenomenon of intracellular propagation of late apoptotic events, such as cytochrome
    c release and caspase activation. The mechanism, prevalence, and speed of apoptosis
    propagation remain unclear. Additionally, no studies have demonstrated propagation
    of the pro-apoptotic protein, BAX. To evaluate the role of BAX in intracellular
    apoptotic propagation, we used high speed live-cell imaging to visualize fluorescently
    tagged-BAX recruitment to mitochondria in four immortalized cell lines. We show
    that propagation of mitochondrial BAX recruitment occurs in parallel to cytochrome
    c and SMAC/Diablo release and is affected by cellular morphology, such that cells
    with processes are more likely to exhibit propagation. The initiation of propagation
    events is most prevalent in the distal tips of processes, while the rate of propagation
    is influenced by the 2-dimensional width of the process. Propagation was rarely
    observed in the cell soma, which exhibited near synchronous recruitment of BAX.
    Propagation velocity is not affected by mitochondrial volume in segments of processes,
    but is negatively affected by mitochondrial density. There was no evidence of
    a propagating wave of increased levels of intracellular calcium ions. Alternatively,
    we did observe a uniform increase in superoxide build-up in cellular mitochondria,
    which was released as a propagating wave simultaneously with the propagating recruitment
    of BAX to the mitochondrial outer membrane.
acknowledgement: This work was supported by National Institute of Health grants R01
  EY030123, P30 EY016665, and T32 GM081061, an unrestricted research grant from Research
  to Prevent Blindness, Inc., and the Frederick A. Davis Endowment from the Department
  of Ophthalmology and Visual Sciences at the University of Wisconsin-Madison.
article_processing_charge: No
article_type: original
author:
- first_name: Joshua A.
  full_name: Grosser, Joshua A.
  last_name: Grosser
- first_name: Margaret E
  full_name: Maes, Margaret E
  id: 3838F452-F248-11E8-B48F-1D18A9856A87
  last_name: Maes
  orcid: 0000-0001-9642-1085
- first_name: Robert W.
  full_name: Nickells, Robert W.
  last_name: Nickells
citation:
  ama: Grosser JA, Maes ME, Nickells RW. Characteristics of intracellular propagation
    of mitochondrial BAX recruitment during apoptosis. <i>Apoptosis</i>. 2021;26(2):132-145.
    doi:<a href="https://doi.org/10.1007/s10495-020-01654-w">10.1007/s10495-020-01654-w</a>
  apa: Grosser, J. A., Maes, M. E., &#38; Nickells, R. W. (2021). Characteristics
    of intracellular propagation of mitochondrial BAX recruitment during apoptosis.
    <i>Apoptosis</i>. Springer Nature. <a href="https://doi.org/10.1007/s10495-020-01654-w">https://doi.org/10.1007/s10495-020-01654-w</a>
  chicago: Grosser, Joshua A., Margaret E Maes, and Robert W. Nickells. “Characteristics
    of Intracellular Propagation of Mitochondrial BAX Recruitment during Apoptosis.”
    <i>Apoptosis</i>. Springer Nature, 2021. <a href="https://doi.org/10.1007/s10495-020-01654-w">https://doi.org/10.1007/s10495-020-01654-w</a>.
  ieee: J. A. Grosser, M. E. Maes, and R. W. Nickells, “Characteristics of intracellular
    propagation of mitochondrial BAX recruitment during apoptosis,” <i>Apoptosis</i>,
    vol. 26, no. 2. Springer Nature, pp. 132–145, 2021.
  ista: Grosser JA, Maes ME, Nickells RW. 2021. Characteristics of intracellular propagation
    of mitochondrial BAX recruitment during apoptosis. Apoptosis. 26(2), 132–145.
  mla: Grosser, Joshua A., et al. “Characteristics of Intracellular Propagation of
    Mitochondrial BAX Recruitment during Apoptosis.” <i>Apoptosis</i>, vol. 26, no.
    2, Springer Nature, 2021, pp. 132–45, doi:<a href="https://doi.org/10.1007/s10495-020-01654-w">10.1007/s10495-020-01654-w</a>.
  short: J.A. Grosser, M.E. Maes, R.W. Nickells, Apoptosis 26 (2021) 132–145.
date_created: 2021-01-17T23:01:11Z
date_published: 2021-02-01T00:00:00Z
date_updated: 2023-08-07T13:32:40Z
day: '01'
department:
- _id: SaSi
doi: 10.1007/s10495-020-01654-w
external_id:
  isi:
  - '000606722600001'
  pmid:
  - '33426618'
intvolume: '        26'
isi: 1
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8082518/
month: '02'
oa: 1
oa_version: Submitted Version
page: 132-145
pmid: 1
publication: Apoptosis
publication_identifier:
  eissn:
  - 1573-675X
  issn:
  - 1360-8185
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Characteristics of intracellular propagation of mitochondrial BAX recruitment
  during apoptosis
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 26
year: '2021'
...
---
_id: '9010'
abstract:
- lang: eng
  text: Availability of the essential macronutrient nitrogen in soil plays a critical
    role in plant growth, development, and impacts agricultural productivity. Plants
    have evolved different strategies for sensing and responding to heterogeneous
    nitrogen distribution. Modulation of root system architecture, including primary
    root growth and branching, is among the most essential plant adaptions to ensure
    adequate nitrogen acquisition. However, the immediate molecular pathways coordinating
    the adjustment of root growth in response to distinct nitrogen sources, such as
    nitrate or ammonium, are poorly understood. Here, we show that growth as manifested
    by cell division and elongation is synchronized by coordinated auxin flux between
    two adjacent outer tissue layers of the root. This coordination is achieved by
    nitrate‐dependent dephosphorylation of the PIN2 auxin efflux carrier at a previously
    uncharacterized phosphorylation site, leading to subsequent PIN2 lateralization
    and thereby regulating auxin flow between adjacent tissues. A dynamic computer
    model based on our experimental data successfully recapitulates experimental observations.
    Our study provides mechanistic insights broadening our understanding of root growth
    mechanisms in dynamic environments.
acknowledged_ssus:
- _id: Bio
acknowledgement: 'We acknowledge Gergely Molnar for critical reading of the manuscript,
  Alexander Johnson for language editing and Yulija Salanenka for technical assistance.
  Work in the Benkova laboratory was supported by the Austrian Science Fund (FWF01_I1774S)
  to KO, RA and EB. Work in the Benkova laboratory was supported by the Austrian Science
  Fund (FWF01_I1774S) to KO, RA and EB and by the DOC Fellowship Programme of the
  AustrianAcademy of Sciences (25008) to C.A. Work in the Wabnik laboratory was supported
  by the Programa de Atraccion de Talento 2017 (Comunidad deMadrid, 2017-T1/BIO-5654
  to K.W.), Severo Ochoa Programme for Centres of Excellence in R&D from the Agencia
  Estatal de Investigacion of Spain (grantSEV-2016-0672 (2017-2021) to K.W. via the
  CBGP) and Programa Estatal de Generacion del Conocimiento y Fortalecimiento Científico
  y Tecnologico del Sistema de I+D+I 2019 (PGC2018-093387-A-I00) from MICIU (to K.W.).
  M.M.was supported by a postdoctoral contract associated to SEV-2016-0672.We acknowledge
  the Bioimaging Facility in IST-Austria and the Advanced Microscopy Facility of the
  Vienna Bio Center Core Facilities, member of the Vienna Bio Center Austria, for
  use of the OMX v43D SIM microscope. AJ was supported by the Austrian Science Fund
  (FWF): I03630 to J.F'
article_number: e106862
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Krisztina
  full_name: Ötvös, Krisztina
  id: 29B901B0-F248-11E8-B48F-1D18A9856A87
  last_name: Ötvös
  orcid: 0000-0002-5503-4983
- first_name: Marco
  full_name: Marconi, Marco
  last_name: Marconi
- first_name: Andrea
  full_name: Vega, Andrea
  last_name: Vega
- first_name: Jose
  full_name: O’Brien, Jose
  last_name: O’Brien
- first_name: Alexander J
  full_name: Johnson, Alexander J
  id: 46A62C3A-F248-11E8-B48F-1D18A9856A87
  last_name: Johnson
  orcid: 0000-0002-2739-8843
- first_name: Rashed
  full_name: Abualia, Rashed
  id: 4827E134-F248-11E8-B48F-1D18A9856A87
  last_name: Abualia
  orcid: 0000-0002-9357-9415
- first_name: Livio
  full_name: Antonielli, Livio
  last_name: Antonielli
- first_name: Juan C
  full_name: Montesinos López, Juan C
  id: 310A8E3E-F248-11E8-B48F-1D18A9856A87
  last_name: Montesinos López
  orcid: 0000-0001-9179-6099
- first_name: Yuzhou
  full_name: Zhang, Yuzhou
  id: 3B6137F2-F248-11E8-B48F-1D18A9856A87
  last_name: Zhang
  orcid: 0000-0003-2627-6956
- first_name: Shutang
  full_name: Tan, Shutang
  id: 2DE75584-F248-11E8-B48F-1D18A9856A87
  last_name: Tan
  orcid: 0000-0002-0471-8285
- first_name: Candela
  full_name: Cuesta, Candela
  id: 33A3C818-F248-11E8-B48F-1D18A9856A87
  last_name: Cuesta
  orcid: 0000-0003-1923-2410
- first_name: Christina
  full_name: Artner, Christina
  id: 45DF286A-F248-11E8-B48F-1D18A9856A87
  last_name: Artner
- first_name: Eleonore
  full_name: Bouguyon, Eleonore
  last_name: Bouguyon
- first_name: Alain
  full_name: Gojon, Alain
  last_name: Gojon
- first_name: Jiří
  full_name: Friml, Jiří
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
- first_name: Rodrigo A.
  full_name: Gutiérrez, Rodrigo A.
  last_name: Gutiérrez
- first_name: Krzysztof T
  full_name: Wabnik, Krzysztof T
  id: 4DE369A4-F248-11E8-B48F-1D18A9856A87
  last_name: Wabnik
  orcid: 0000-0001-7263-0560
- first_name: Eva
  full_name: Benková, Eva
  id: 38F4F166-F248-11E8-B48F-1D18A9856A87
  last_name: Benková
  orcid: 0000-0002-8510-9739
citation:
  ama: Ötvös K, Marconi M, Vega A, et al. Modulation of plant root growth by nitrogen
    source-defined regulation of polar auxin transport. <i>EMBO Journal</i>. 2021;40(3).
    doi:<a href="https://doi.org/10.15252/embj.2020106862">10.15252/embj.2020106862</a>
  apa: Ötvös, K., Marconi, M., Vega, A., O’Brien, J., Johnson, A. J., Abualia, R.,
    … Benková, E. (2021). Modulation of plant root growth by nitrogen source-defined
    regulation of polar auxin transport. <i>EMBO Journal</i>. Embo Press. <a href="https://doi.org/10.15252/embj.2020106862">https://doi.org/10.15252/embj.2020106862</a>
  chicago: Ötvös, Krisztina, Marco Marconi, Andrea Vega, Jose O’Brien, Alexander J
    Johnson, Rashed Abualia, Livio Antonielli, et al. “Modulation of Plant Root Growth
    by Nitrogen Source-Defined Regulation of Polar Auxin Transport.” <i>EMBO Journal</i>.
    Embo Press, 2021. <a href="https://doi.org/10.15252/embj.2020106862">https://doi.org/10.15252/embj.2020106862</a>.
  ieee: K. Ötvös <i>et al.</i>, “Modulation of plant root growth by nitrogen source-defined
    regulation of polar auxin transport,” <i>EMBO Journal</i>, vol. 40, no. 3. Embo
    Press, 2021.
  ista: Ötvös K, Marconi M, Vega A, O’Brien J, Johnson AJ, Abualia R, Antonielli L,
    Montesinos López JC, Zhang Y, Tan S, Cuesta C, Artner C, Bouguyon E, Gojon A,
    Friml J, Gutiérrez RA, Wabnik KT, Benková E. 2021. Modulation of plant root growth
    by nitrogen source-defined regulation of polar auxin transport. EMBO Journal.
    40(3), e106862.
  mla: Ötvös, Krisztina, et al. “Modulation of Plant Root Growth by Nitrogen Source-Defined
    Regulation of Polar Auxin Transport.” <i>EMBO Journal</i>, vol. 40, no. 3, e106862,
    Embo Press, 2021, doi:<a href="https://doi.org/10.15252/embj.2020106862">10.15252/embj.2020106862</a>.
  short: K. Ötvös, M. Marconi, A. Vega, J. O’Brien, A.J. Johnson, R. Abualia, L. Antonielli,
    J.C. Montesinos López, Y. Zhang, S. Tan, C. Cuesta, C. Artner, E. Bouguyon, A.
    Gojon, J. Friml, R.A. Gutiérrez, K.T. Wabnik, E. Benková, EMBO Journal 40 (2021).
date_created: 2021-01-17T23:01:12Z
date_published: 2021-02-01T00:00:00Z
date_updated: 2024-03-25T23:30:22Z
day: '01'
ddc:
- '580'
department:
- _id: JiFr
- _id: EvBe
doi: 10.15252/embj.2020106862
external_id:
  isi:
  - '000604645600001'
  pmid:
  - ' 33399250'
file:
- access_level: open_access
  checksum: dc55c900f3b061d6c2790b8813d759a3
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  creator: dernst
  date_created: 2021-02-11T12:28:29Z
  date_updated: 2021-02-11T12:28:29Z
  file_id: '9110'
  file_name: 2021_Embo_Otvos.pdf
  file_size: 2358617
  relation: main_file
  success: 1
file_date_updated: 2021-02-11T12:28:29Z
has_accepted_license: '1'
intvolume: '        40'
isi: 1
issue: '3'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 2542D156-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: I 1774-B16
  name: Hormone cross-talk drives nutrient dependent plant development
- _id: 2685A872-B435-11E9-9278-68D0E5697425
  name: Hormonal regulation of plant adaptive responses to environmental signals
- _id: 26538374-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: I03630
  name: Molecular mechanisms of endocytic cargo recognition in plants
publication: EMBO Journal
publication_identifier:
  eissn:
  - '14602075'
  issn:
  - '02614189'
publication_status: published
publisher: Embo Press
quality_controlled: '1'
related_material:
  link:
  - description: News on IST Homepage
    relation: press_release
    url: https://ist.ac.at/en/news/a-plants-way-to-its-favorite-food/
  record:
  - id: '10303'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: Modulation of plant root growth by nitrogen source-defined regulation of polar
  auxin transport
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 40
year: '2021'
...
---
_id: '9020'
abstract:
- lang: eng
  text: 'We study dynamics and thermodynamics of ion transport in narrow, water-filled
    channels, considered as effective 1D Coulomb systems. The long range nature of
    the inter-ion interactions comes about due to the dielectric constants mismatch
    between the water and the surrounding medium, confining the electric filed to
    stay mostly within the water-filled channel. Statistical mechanics of such Coulomb
    systems is dominated by entropic effects which may be accurately accounted for
    by mapping onto an effective quantum mechanics. In presence of multivalent ions
    the corresponding quantum mechanics appears to be non-Hermitian. In this review
    we discuss a framework for semiclassical calculations for the effective non-Hermitian
    Hamiltonians. Non-Hermiticity elevates WKB action integrals from the real line
    to closed cycles on a complex Riemann surfaces where direct calculations are not
    attainable. We circumvent this issue by applying tools from algebraic topology,
    such as the Picard-Fuchs equation. We discuss how its solutions relate to the
    thermodynamics and correlation functions of multivalent solutions within narrow,
    water-filled channels. '
acknowledgement: "A.K. was supported by NSF grants DMR-2037654. T.G. acknowledges
  funding from the Institute of Science and Technology (IST) Austria, and from the
  European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie
  Grant Agreement No. 754411.\r\nWe are indebted to Boris Shklovskii for introducing
  us to the problem, and Alexander Gorsky and Peter Koroteev for introducing us to
  the Picard-Fuchs methods. A very special thanks goes to Michael Janas for several
  years of excellent collaboration on these topics. TG thanks Michael Kreshchuk for
  introduction to the exact WKB method and great collaboration on related projects.
  Figure 3 and Figure 4 are reproduced from Reference [25] with friendly permission
  by the Russian Academy of Sciences. Figure 2, Figure 4, Figure 5, Figure 6, and
  Figure 8 are reproduced from Reference [26] with friendly permission by IOP Publishing."
article_number: e23010125
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: Tobias
  full_name: Gulden, Tobias
  id: 1083E038-9F73-11E9-A4B5-532AE6697425
  last_name: Gulden
  orcid: 0000-0001-6814-7541
- first_name: Alex
  full_name: Kamenev, Alex
  last_name: Kamenev
citation:
  ama: Gulden T, Kamenev A. Dynamics of ion channels via non-hermitian quantum mechanics.
    <i>Entropy</i>. 2021;23(1). doi:<a href="https://doi.org/10.3390/e23010125">10.3390/e23010125</a>
  apa: Gulden, T., &#38; Kamenev, A. (2021). Dynamics of ion channels via non-hermitian
    quantum mechanics. <i>Entropy</i>. MDPI. <a href="https://doi.org/10.3390/e23010125">https://doi.org/10.3390/e23010125</a>
  chicago: Gulden, Tobias, and Alex Kamenev. “Dynamics of Ion Channels via Non-Hermitian
    Quantum Mechanics.” <i>Entropy</i>. MDPI, 2021. <a href="https://doi.org/10.3390/e23010125">https://doi.org/10.3390/e23010125</a>.
  ieee: T. Gulden and A. Kamenev, “Dynamics of ion channels via non-hermitian quantum
    mechanics,” <i>Entropy</i>, vol. 23, no. 1. MDPI, 2021.
  ista: Gulden T, Kamenev A. 2021. Dynamics of ion channels via non-hermitian quantum
    mechanics. Entropy. 23(1), e23010125.
  mla: Gulden, Tobias, and Alex Kamenev. “Dynamics of Ion Channels via Non-Hermitian
    Quantum Mechanics.” <i>Entropy</i>, vol. 23, no. 1, e23010125, MDPI, 2021, doi:<a
    href="https://doi.org/10.3390/e23010125">10.3390/e23010125</a>.
  short: T. Gulden, A. Kamenev, Entropy 23 (2021).
date_created: 2021-01-19T11:12:06Z
date_published: 2021-01-19T00:00:00Z
date_updated: 2023-08-07T13:34:18Z
day: '19'
ddc:
- '530'
department:
- _id: MaSe
doi: 10.3390/e23010125
ec_funded: 1
external_id:
  arxiv:
  - '2012.01390'
  isi:
  - '000610122000001'
file:
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  checksum: 6cd0e706156827c45c740534bd32c179
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  date_created: 2021-01-19T11:11:14Z
  date_updated: 2021-01-19T11:11:14Z
  file_id: '9021'
  file_name: Final published paper.pdf
  file_size: 981285
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file_date_updated: 2021-01-19T11:11:14Z
has_accepted_license: '1'
intvolume: '        23'
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issue: '1'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '754411'
  name: ISTplus - Postdoctoral Fellowships
publication: Entropy
publication_identifier:
  eissn:
  - 1099-4300
publication_status: published
publisher: MDPI
quality_controlled: '1'
status: public
title: Dynamics of ion channels via non-hermitian quantum mechanics
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 23
year: '2021'
...
---
_id: '9022'
abstract:
- lang: eng
  text: "In the first part of the thesis we consider Hermitian random matrices. Firstly,
    we consider sample covariance matrices XX∗ with X having independent identically
    distributed (i.i.d.) centred entries. We prove a Central Limit Theorem for differences
    of linear statistics of XX∗ and its minor after removing the first column of X.
    Secondly, we consider Wigner-type matrices and prove that the eigenvalue statistics
    near cusp singularities of the limiting density of states are universal and that
    they form a Pearcey process. Since the limiting eigenvalue distribution admits
    only square root (edge) and cubic root (cusp) singularities, this concludes the
    third and last remaining case of the Wigner-Dyson-Mehta universality conjecture.
    The main technical ingredients are an optimal local law at the cusp, and the proof
    of the fast relaxation to equilibrium of the Dyson Brownian motion in the cusp
    regime.\r\nIn the second part we consider non-Hermitian matrices X with centred
    i.i.d. entries. We normalise the entries of X to have variance N −1. It is well
    known that the empirical eigenvalue density converges to the uniform distribution
    on the unit disk (circular law). In the first project, we prove universality of
    the local eigenvalue statistics close to the edge of the spectrum. This is the
    non-Hermitian analogue of the TracyWidom universality at the Hermitian edge. Technically
    we analyse the evolution of the spectral distribution of X along the Ornstein-Uhlenbeck
    flow for very long time\r\n(up to t = +∞). In the second project, we consider
    linear statistics of eigenvalues for macroscopic test functions f in the Sobolev
    space H2+ϵ and prove their convergence to the projection of the Gaussian Free
    Field on the unit disk. We prove this result for non-Hermitian matrices with real
    or complex entries. The main technical ingredients are: (i) local law for products
    of two resolvents at different spectral parameters, (ii) analysis of correlated
    Dyson Brownian motions.\r\nIn the third and final part we discuss the mathematically
    rigorous application of supersymmetric techniques (SUSY ) to give a lower tail
    estimate of the lowest singular value of X − z, with z ∈ C. More precisely, we
    use superbosonisation formula to give an integral representation of the resolvent
    of (X − z)(X − z)∗ which reduces to two and three contour integrals in the complex
    and real case, respectively. The rigorous analysis of these integrals is quite
    challenging since simple saddle point analysis cannot be applied (the main contribution
    comes from a non-trivial manifold). Our result\r\nimproves classical smoothing
    inequalities in the regime |z| ≈ 1; this result is essential to prove edge universality
    for i.i.d. non-Hermitian matrices."
acknowledgement: I gratefully acknowledge the financial support from the European
  Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie
  Grant Agreement No. 665385 and my advisor’s ERC Advanced Grant No. 338804.
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Giorgio
  full_name: Cipolloni, Giorgio
  id: 42198EFA-F248-11E8-B48F-1D18A9856A87
  last_name: Cipolloni
  orcid: 0000-0002-4901-7992
citation:
  ama: Cipolloni G. Fluctuations in the spectrum of random matrices. 2021. doi:<a
    href="https://doi.org/10.15479/AT:ISTA:9022">10.15479/AT:ISTA:9022</a>
  apa: Cipolloni, G. (2021). <i>Fluctuations in the spectrum of random matrices</i>.
    Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/AT:ISTA:9022">https://doi.org/10.15479/AT:ISTA:9022</a>
  chicago: Cipolloni, Giorgio. “Fluctuations in the Spectrum of Random Matrices.”
    Institute of Science and Technology Austria, 2021. <a href="https://doi.org/10.15479/AT:ISTA:9022">https://doi.org/10.15479/AT:ISTA:9022</a>.
  ieee: G. Cipolloni, “Fluctuations in the spectrum of random matrices,” Institute
    of Science and Technology Austria, 2021.
  ista: Cipolloni G. 2021. Fluctuations in the spectrum of random matrices. Institute
    of Science and Technology Austria.
  mla: Cipolloni, Giorgio. <i>Fluctuations in the Spectrum of Random Matrices</i>.
    Institute of Science and Technology Austria, 2021, doi:<a href="https://doi.org/10.15479/AT:ISTA:9022">10.15479/AT:ISTA:9022</a>.
  short: G. Cipolloni, Fluctuations in the Spectrum of Random Matrices, Institute
    of Science and Technology Austria, 2021.
date_created: 2021-01-21T18:16:54Z
date_published: 2021-01-25T00:00:00Z
date_updated: 2023-09-07T13:29:32Z
day: '25'
ddc:
- '510'
degree_awarded: PhD
department:
- _id: GradSch
- _id: LaEr
doi: 10.15479/AT:ISTA:9022
ec_funded: 1
file:
- access_level: open_access
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  date_updated: 2021-01-25T14:19:03Z
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  date_updated: 2021-01-25T14:19:10Z
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  file_size: 12775206
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file_date_updated: 2021-01-25T14:19:10Z
has_accepted_license: '1'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: '380'
project:
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '665385'
  name: International IST Doctoral Program
- _id: 258DCDE6-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '338804'
  name: Random matrices, universality and disordered quantum systems
publication_identifier:
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
status: public
supervisor:
- first_name: László
  full_name: Erdös, László
  id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
  last_name: Erdös
  orcid: 0000-0001-5366-9603
title: Fluctuations in the spectrum of random matrices
type: dissertation
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2021'
...
---
_id: '9036'
abstract:
- lang: eng
  text: In this short note, we prove that the square root of the quantum Jensen-Shannon
    divergence is a true metric on the cone of positive matrices, and hence in particular
    on the quantum state space.
acknowledgement: D. Virosztek was supported by the European Union's Horizon 2020 research
  and innovation programme under the Marie Skłodowska-Curie Grant Agreement No. 846294,
  and partially supported by the Hungarian National Research, Development and Innovation
  Office (NKFIH) via grants no. K124152, and no. KH129601.
article_number: '107595'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Daniel
  full_name: Virosztek, Daniel
  id: 48DB45DA-F248-11E8-B48F-1D18A9856A87
  last_name: Virosztek
  orcid: 0000-0003-1109-5511
citation:
  ama: Virosztek D. The metric property of the quantum Jensen-Shannon divergence.
    <i>Advances in Mathematics</i>. 2021;380(3). doi:<a href="https://doi.org/10.1016/j.aim.2021.107595">10.1016/j.aim.2021.107595</a>
  apa: Virosztek, D. (2021). The metric property of the quantum Jensen-Shannon divergence.
    <i>Advances in Mathematics</i>. Elsevier. <a href="https://doi.org/10.1016/j.aim.2021.107595">https://doi.org/10.1016/j.aim.2021.107595</a>
  chicago: Virosztek, Daniel. “The Metric Property of the Quantum Jensen-Shannon Divergence.”
    <i>Advances in Mathematics</i>. Elsevier, 2021. <a href="https://doi.org/10.1016/j.aim.2021.107595">https://doi.org/10.1016/j.aim.2021.107595</a>.
  ieee: D. Virosztek, “The metric property of the quantum Jensen-Shannon divergence,”
    <i>Advances in Mathematics</i>, vol. 380, no. 3. Elsevier, 2021.
  ista: Virosztek D. 2021. The metric property of the quantum Jensen-Shannon divergence.
    Advances in Mathematics. 380(3), 107595.
  mla: Virosztek, Daniel. “The Metric Property of the Quantum Jensen-Shannon Divergence.”
    <i>Advances in Mathematics</i>, vol. 380, no. 3, 107595, Elsevier, 2021, doi:<a
    href="https://doi.org/10.1016/j.aim.2021.107595">10.1016/j.aim.2021.107595</a>.
  short: D. Virosztek, Advances in Mathematics 380 (2021).
date_created: 2021-01-22T17:55:17Z
date_published: 2021-03-26T00:00:00Z
date_updated: 2023-08-07T13:34:48Z
day: '26'
department:
- _id: LaEr
doi: 10.1016/j.aim.2021.107595
ec_funded: 1
external_id:
  arxiv:
  - '1910.10447'
  isi:
  - '000619676100035'
intvolume: '       380'
isi: 1
issue: '3'
keyword:
- General Mathematics
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1910.10447
month: '03'
oa: 1
oa_version: Preprint
project:
- _id: 26A455A6-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '846294'
  name: Geometric study of Wasserstein spaces and free probability
publication: Advances in Mathematics
publication_identifier:
  issn:
  - 0001-8708
publication_status: published
publisher: Elsevier
quality_controlled: '1'
status: public
title: The metric property of the quantum Jensen-Shannon divergence
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 380
year: '2021'
...
---
_id: '9037'
abstract:
- lang: eng
  text: "We continue our study of ‘no‐dimension’ analogues of basic theorems in combinatorial
    and convex geometry in Banach spaces. We generalize some results of the paper
    (Adiprasito, Bárány and Mustafa, ‘Theorems of Carathéodory, Helly, and Tverberg
    without dimension’, Proceedings of the Thirtieth Annual ACM‐SIAM Symposium on
    Discrete Algorithms (Society for Industrial and Applied Mathematics, San Diego,
    California, 2019) 2350–2360) and prove no‐dimension versions of the colored Tverberg
    theorem, the selection lemma and the weak  \U0001D700 ‐net theorem in Banach spaces
    of type  \U0001D45D>1 . To prove these results, we use the original ideas of Adiprasito,
    Bárány and Mustafa for the Euclidean case, our no‐dimension version of the Radon
    theorem and slightly modified version of the celebrated Maurey lemma."
acknowledgement: "I wish to thank Imre Bárány for bringing the problem to my attention.
  I am grateful to Marton Naszódi and Igor Tsiutsiurupa for useful remarks and help
  with the text.\r\nThe author acknowledges the financial support from the Ministry
  of Educational and Science of the Russian Federation in the framework of MegaGrant
  no 075‐15‐2019‐1926."
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Grigory
  full_name: Ivanov, Grigory
  id: 87744F66-5C6F-11EA-AFE0-D16B3DDC885E
  last_name: Ivanov
citation:
  ama: Ivanov G. No-dimension Tverberg’s theorem and its corollaries in Banach spaces
    of type p. <i>Bulletin of the London Mathematical Society</i>. 2021;53(2):631-641.
    doi:<a href="https://doi.org/10.1112/blms.12449">10.1112/blms.12449</a>
  apa: Ivanov, G. (2021). No-dimension Tverberg’s theorem and its corollaries in Banach
    spaces of type p. <i>Bulletin of the London Mathematical Society</i>. London Mathematical
    Society. <a href="https://doi.org/10.1112/blms.12449">https://doi.org/10.1112/blms.12449</a>
  chicago: Ivanov, Grigory. “No-Dimension Tverberg’s Theorem and Its Corollaries in
    Banach Spaces of Type P.” <i>Bulletin of the London Mathematical Society</i>.
    London Mathematical Society, 2021. <a href="https://doi.org/10.1112/blms.12449">https://doi.org/10.1112/blms.12449</a>.
  ieee: G. Ivanov, “No-dimension Tverberg’s theorem and its corollaries in Banach
    spaces of type p,” <i>Bulletin of the London Mathematical Society</i>, vol. 53,
    no. 2. London Mathematical Society, pp. 631–641, 2021.
  ista: Ivanov G. 2021. No-dimension Tverberg’s theorem and its corollaries in Banach
    spaces of type p. Bulletin of the London Mathematical Society. 53(2), 631–641.
  mla: Ivanov, Grigory. “No-Dimension Tverberg’s Theorem and Its Corollaries in Banach
    Spaces of Type P.” <i>Bulletin of the London Mathematical Society</i>, vol. 53,
    no. 2, London Mathematical Society, 2021, pp. 631–41, doi:<a href="https://doi.org/10.1112/blms.12449">10.1112/blms.12449</a>.
  short: G. Ivanov, Bulletin of the London Mathematical Society 53 (2021) 631–641.
date_created: 2021-01-24T23:01:08Z
date_published: 2021-04-01T00:00:00Z
date_updated: 2023-08-07T13:35:20Z
day: '01'
ddc:
- '510'
department:
- _id: UlWa
doi: 10.1112/blms.12449
external_id:
  arxiv:
  - '1912.08561'
  isi:
  - '000607265100001'
file:
- access_level: open_access
  checksum: e6ceaa6470d835eb4c211cbdd38fdfd1
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  creator: kschuh
  date_created: 2021-08-06T09:59:45Z
  date_updated: 2021-08-06T09:59:45Z
  file_id: '9796'
  file_name: 2021_BLMS_Ivanov.pdf
  file_size: 194550
  relation: main_file
  success: 1
file_date_updated: 2021-08-06T09:59:45Z
has_accepted_license: '1'
intvolume: '        53'
isi: 1
issue: '2'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
page: 631-641
publication: Bulletin of the London Mathematical Society
publication_identifier:
  eissn:
  - '14692120'
  issn:
  - '00246093'
publication_status: published
publisher: London Mathematical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: No-dimension Tverberg's theorem and its corollaries in Banach spaces of type
  p
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 53
year: '2021'
...
---
_id: '9046'
acknowledgement: Our work was supported by the Swedish Research Council (grant 2017-01527)
  to DIA
article_number: e1009172
article_processing_charge: No
article_type: original
author:
- first_name: Roderich
  full_name: Römhild, Roderich
  id: 68E56E44-62B0-11EA-B963-444F3DDC885E
  last_name: Römhild
  orcid: 0000-0001-9480-5261
- first_name: Dan I.
  full_name: Andersson, Dan I.
  last_name: Andersson
citation:
  ama: Römhild R, Andersson DI. Mechanisms and therapeutic potential of collateral
    sensitivity to antibiotics. <i>PLoS Pathogens</i>. 2021;17(1). doi:<a href="https://doi.org/10.1371/journal.ppat.1009172">10.1371/journal.ppat.1009172</a>
  apa: Römhild, R., &#38; Andersson, D. I. (2021). Mechanisms and therapeutic potential
    of collateral sensitivity to antibiotics. <i>PLoS Pathogens</i>. Public Library
    of Science. <a href="https://doi.org/10.1371/journal.ppat.1009172">https://doi.org/10.1371/journal.ppat.1009172</a>
  chicago: Römhild, Roderich, and Dan I. Andersson. “Mechanisms and Therapeutic Potential
    of Collateral Sensitivity to Antibiotics.” <i>PLoS Pathogens</i>. Public Library
    of Science, 2021. <a href="https://doi.org/10.1371/journal.ppat.1009172">https://doi.org/10.1371/journal.ppat.1009172</a>.
  ieee: R. Römhild and D. I. Andersson, “Mechanisms and therapeutic potential of collateral
    sensitivity to antibiotics,” <i>PLoS Pathogens</i>, vol. 17, no. 1. Public Library
    of Science, 2021.
  ista: Römhild R, Andersson DI. 2021. Mechanisms and therapeutic potential of collateral
    sensitivity to antibiotics. PLoS Pathogens. 17(1), e1009172.
  mla: Römhild, Roderich, and Dan I. Andersson. “Mechanisms and Therapeutic Potential
    of Collateral Sensitivity to Antibiotics.” <i>PLoS Pathogens</i>, vol. 17, no.
    1, e1009172, Public Library of Science, 2021, doi:<a href="https://doi.org/10.1371/journal.ppat.1009172">10.1371/journal.ppat.1009172</a>.
  short: R. Römhild, D.I. Andersson, PLoS Pathogens 17 (2021).
date_created: 2021-01-31T23:01:21Z
date_published: 2021-01-14T00:00:00Z
date_updated: 2023-08-07T13:36:55Z
day: '14'
ddc:
- '570'
department:
- _id: CaGu
doi: 10.1371/journal.ppat.1009172
external_id:
  isi:
  - '000610190400007'
  pmid:
  - '33444399'
file:
- access_level: open_access
  checksum: d745d7f8fcbb9b95fea16a36f94dee31
  content_type: application/pdf
  creator: dernst
  date_created: 2021-02-03T12:13:03Z
  date_updated: 2021-02-03T12:13:03Z
  file_id: '9070'
  file_name: 2021_PlosPathogens_Roemhild.pdf
  file_size: 570066
  relation: main_file
  success: 1
file_date_updated: 2021-02-03T12:13:03Z
has_accepted_license: '1'
intvolume: '        17'
isi: 1
issue: '1'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
pmid: 1
publication: PLoS Pathogens
publication_identifier:
  eissn:
  - '15537374'
  issn:
  - '15537366'
publication_status: published
publisher: Public Library of Science
quality_controlled: '1'
scopus_import: '1'
status: public
title: Mechanisms and therapeutic potential of collateral sensitivity to antibiotics
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 17
year: '2021'
...
---
_id: '9047'
abstract:
- lang: eng
  text: This work analyzes the latency of the simplified successive cancellation (SSC)
    decoding scheme for polar codes proposed by Alamdar-Yazdi and Kschischang. It
    is shown that, unlike conventional successive cancellation decoding, where latency
    is linear in the block length, the latency of SSC decoding is sublinear. More
    specifically, the latency of SSC decoding is O(N1−1/μ) , where N is the block
    length and μ is the scaling exponent of the channel, which captures the speed
    of convergence of the rate to capacity. Numerical results demonstrate the tightness
    of the bound and show that most of the latency reduction arises from the parallel
    decoding of subcodes of rate 0 or 1.
acknowledgement: M. Mondelli was partially supported by grants NSF DMS-1613091, CCF-1714305,
  IIS-1741162, and ONR N00014-18-1-2729. S. A. Hashemi is supported by a Postdoctoral
  Fellowship from the Natural Sciences and Engineering Research Council of Canada
  (NSERC) and by Huawei. The authors would like to thank the anonymous reviewers for
  their comments that helped improving the quality of the manuscript.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Marco
  full_name: Mondelli, Marco
  id: 27EB676C-8706-11E9-9510-7717E6697425
  last_name: Mondelli
  orcid: 0000-0002-3242-7020
- first_name: Seyyed Ali
  full_name: Hashemi, Seyyed Ali
  last_name: Hashemi
- first_name: John M.
  full_name: Cioffi, John M.
  last_name: Cioffi
- first_name: Andrea
  full_name: Goldsmith, Andrea
  last_name: Goldsmith
citation:
  ama: Mondelli M, Hashemi SA, Cioffi JM, Goldsmith A. Sublinear latency for simplified
    successive cancellation decoding of polar codes. <i>IEEE Transactions on Wireless
    Communications</i>. 2021;20(1):18-27. doi:<a href="https://doi.org/10.1109/TWC.2020.3022922">10.1109/TWC.2020.3022922</a>
  apa: Mondelli, M., Hashemi, S. A., Cioffi, J. M., &#38; Goldsmith, A. (2021). Sublinear
    latency for simplified successive cancellation decoding of polar codes. <i>IEEE
    Transactions on Wireless Communications</i>. IEEE. <a href="https://doi.org/10.1109/TWC.2020.3022922">https://doi.org/10.1109/TWC.2020.3022922</a>
  chicago: Mondelli, Marco, Seyyed Ali Hashemi, John M. Cioffi, and Andrea Goldsmith.
    “Sublinear Latency for Simplified Successive Cancellation Decoding of Polar Codes.”
    <i>IEEE Transactions on Wireless Communications</i>. IEEE, 2021. <a href="https://doi.org/10.1109/TWC.2020.3022922">https://doi.org/10.1109/TWC.2020.3022922</a>.
  ieee: M. Mondelli, S. A. Hashemi, J. M. Cioffi, and A. Goldsmith, “Sublinear latency
    for simplified successive cancellation decoding of polar codes,” <i>IEEE Transactions
    on Wireless Communications</i>, vol. 20, no. 1. IEEE, pp. 18–27, 2021.
  ista: Mondelli M, Hashemi SA, Cioffi JM, Goldsmith A. 2021. Sublinear latency for
    simplified successive cancellation decoding of polar codes. IEEE Transactions
    on Wireless Communications. 20(1), 18–27.
  mla: Mondelli, Marco, et al. “Sublinear Latency for Simplified Successive Cancellation
    Decoding of Polar Codes.” <i>IEEE Transactions on Wireless Communications</i>,
    vol. 20, no. 1, IEEE, 2021, pp. 18–27, doi:<a href="https://doi.org/10.1109/TWC.2020.3022922">10.1109/TWC.2020.3022922</a>.
  short: M. Mondelli, S.A. Hashemi, J.M. Cioffi, A. Goldsmith, IEEE Transactions on
    Wireless Communications 20 (2021) 18–27.
date_created: 2021-01-31T23:01:21Z
date_published: 2021-01-01T00:00:00Z
date_updated: 2023-08-07T13:36:25Z
day: '01'
department:
- _id: MaMo
doi: 10.1109/TWC.2020.3022922
external_id:
  arxiv:
  - '1909.04892'
  isi:
  - '000607808800002'
intvolume: '        20'
isi: 1
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1909.04892
month: '01'
oa: 1
oa_version: Preprint
page: 18-27
publication: IEEE Transactions on Wireless Communications
publication_identifier:
  eissn:
  - '15582248'
  issn:
  - '15361276'
publication_status: published
publisher: IEEE
quality_controlled: '1'
related_material:
  record:
  - id: '8536'
    relation: earlier_version
    status: public
scopus_import: '1'
status: public
title: Sublinear latency for simplified successive cancellation decoding of polar
  codes
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 20
year: '2021'
...
---
_id: '9048'
abstract:
- lang: eng
  text: The analogy between an equilibrium partition function and the return probability
    in many-body unitary dynamics has led to the concept of dynamical quantum phase
    transition (DQPT). DQPTs are defined by nonanalyticities in the return amplitude
    and are present in many models. In some cases, DQPTs can be related to equilibrium
    concepts, such as order parameters, yet their universal description is an open
    question. In this Letter, we provide first steps toward a classification of DQPTs
    by using a matrix product state description of unitary dynamics in the thermodynamic
    limit. This allows us to distinguish the two limiting cases of “precession” and
    “entanglement” DQPTs, which are illustrated using an analytical description in
    the quantum Ising model. While precession DQPTs are characterized by a large entanglement
    gap and are semiclassical in their nature, entanglement DQPTs occur near avoided
    crossings in the entanglement spectrum and can be distinguished by a complex pattern
    of nonlocal correlations. We demonstrate the existence of precession and entanglement
    DQPTs beyond Ising models, discuss observables that can distinguish them, and
    relate their interplay to complex DQPT phenomenology.
acknowledgement: "S. D. N. acknowledges funding from the Institute of Science and
  Technology (IST) Austria and from the European Union’s Horizon 2020 Research and
  Innovation Programme under the Marie Skłodowska-Curie Grant Agreement No. 754411.
  A. M. and M. S. were supported by the European Research Council (ERC) under the
  European Union’s Horizon 2020 Research and\r\nInnovation Programme (Grant Agreement
  No. 850899)."
article_number: '040602'
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: Stefano
  full_name: De Nicola, Stefano
  id: 42832B76-F248-11E8-B48F-1D18A9856A87
  last_name: De Nicola
  orcid: 0000-0002-4842-6671
- first_name: Alexios
  full_name: Michailidis, Alexios
  id: 36EBAD38-F248-11E8-B48F-1D18A9856A87
  last_name: Michailidis
  orcid: 0000-0002-8443-1064
- first_name: Maksym
  full_name: Serbyn, Maksym
  id: 47809E7E-F248-11E8-B48F-1D18A9856A87
  last_name: Serbyn
  orcid: 0000-0002-2399-5827
citation:
  ama: De Nicola S, Michailidis A, Serbyn M. Entanglement view of dynamical quantum
    phase transitions. <i>Physical Review Letters</i>. 2021;126(4). doi:<a href="https://doi.org/10.1103/physrevlett.126.040602">10.1103/physrevlett.126.040602</a>
  apa: De Nicola, S., Michailidis, A., &#38; Serbyn, M. (2021). Entanglement view
    of dynamical quantum phase transitions. <i>Physical Review Letters</i>. American
    Physical Society. <a href="https://doi.org/10.1103/physrevlett.126.040602">https://doi.org/10.1103/physrevlett.126.040602</a>
  chicago: De Nicola, Stefano, Alexios Michailidis, and Maksym Serbyn. “Entanglement
    View of Dynamical Quantum Phase Transitions.” <i>Physical Review Letters</i>.
    American Physical Society, 2021. <a href="https://doi.org/10.1103/physrevlett.126.040602">https://doi.org/10.1103/physrevlett.126.040602</a>.
  ieee: S. De Nicola, A. Michailidis, and M. Serbyn, “Entanglement view of dynamical
    quantum phase transitions,” <i>Physical Review Letters</i>, vol. 126, no. 4. American
    Physical Society, 2021.
  ista: De Nicola S, Michailidis A, Serbyn M. 2021. Entanglement view of dynamical
    quantum phase transitions. Physical Review Letters. 126(4), 040602.
  mla: De Nicola, Stefano, et al. “Entanglement View of Dynamical Quantum Phase Transitions.”
    <i>Physical Review Letters</i>, vol. 126, no. 4, 040602, American Physical Society,
    2021, doi:<a href="https://doi.org/10.1103/physrevlett.126.040602">10.1103/physrevlett.126.040602</a>.
  short: S. De Nicola, A. Michailidis, M. Serbyn, Physical Review Letters 126 (2021).
date_created: 2021-02-01T09:20:00Z
date_published: 2021-01-29T00:00:00Z
date_updated: 2023-09-05T12:08:58Z
day: '29'
ddc:
- '530'
department:
- _id: MaSe
doi: 10.1103/physrevlett.126.040602
ec_funded: 1
external_id:
  arxiv:
  - '2008.04894'
  isi:
  - '000613148200001'
file:
- access_level: open_access
  checksum: d9acbc502390ed7a97e631d23ae19ecd
  content_type: application/pdf
  creator: dernst
  date_created: 2021-02-03T12:47:04Z
  date_updated: 2021-02-03T12:47:04Z
  file_id: '9074'
  file_name: 2021_PhysicalRevLett_DeNicola.pdf
  file_size: 398075
  relation: main_file
  success: 1
file_date_updated: 2021-02-03T12:47:04Z
has_accepted_license: '1'
intvolume: '       126'
isi: 1
issue: '4'
keyword:
- General Physics and Astronomy
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '754411'
  name: ISTplus - Postdoctoral Fellowships
- _id: 23841C26-32DE-11EA-91FC-C7463DDC885E
  call_identifier: H2020
  grant_number: '850899'
  name: 'Non-Ergodic Quantum Matter: Universality, Dynamics and Control'
publication: Physical Review Letters
publication_identifier:
  eissn:
  - 1079-7114
  issn:
  - 0031-9007
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
status: public
title: Entanglement view of dynamical quantum phase transitions
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 126
year: '2021'
...
---
_id: '9056'
abstract:
- lang: eng
  text: "In this thesis we study persistence of multi-covers of Euclidean balls and
    the geometric structures underlying their computation, in particular Delaunay
    mosaics and Voronoi tessellations. The k-fold cover for some discrete input point
    set consists of the space where at least k balls of radius r around the input
    points overlap. Persistence is a notion that captures, in some sense, the topology
    of the shape underlying the input. While persistence is usually computed for the
    union of balls, the k-fold cover is of interest as it captures local density,\r\nand
    thus might approximate the shape of the input better if the input data is noisy.
    To compute persistence of these k-fold covers, we need a discretization that is
    provided by higher-order Delaunay mosaics. We present and implement a simple and
    efficient algorithm for the computation of higher-order Delaunay mosaics, and
    use it to give experimental results for their combinatorial properties. The algorithm
    makes use of a new geometric structure, the rhomboid tiling. It contains the higher-order
    Delaunay mosaics as slices, and by introducing a filtration\r\nfunction on the
    tiling, we also obtain higher-order α-shapes as slices. These allow us to compute
    persistence of the multi-covers for varying radius r; the computation for varying
    k is less straight-foward and involves the rhomboid tiling directly. We apply
    our algorithms to experimental sphere packings to shed light on their structural
    properties. Finally, inspired by periodic structures in packings and materials,
    we propose and implement an algorithm for periodic Delaunay triangulations to
    be integrated into the Computational Geometry Algorithms Library (CGAL), and discuss
    the implications on persistence for periodic data sets."
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Georg F
  full_name: Osang, Georg F
  id: 464B40D6-F248-11E8-B48F-1D18A9856A87
  last_name: Osang
  orcid: 0000-0002-8882-5116
citation:
  ama: Osang GF. Multi-cover persistence and Delaunay mosaics. 2021. doi:<a href="https://doi.org/10.15479/AT:ISTA:9056">10.15479/AT:ISTA:9056</a>
  apa: Osang, G. F. (2021). <i>Multi-cover persistence and Delaunay mosaics</i>. Institute
    of Science and Technology Austria, Klosterneuburg. <a href="https://doi.org/10.15479/AT:ISTA:9056">https://doi.org/10.15479/AT:ISTA:9056</a>
  chicago: Osang, Georg F. “Multi-Cover Persistence and Delaunay Mosaics.” Institute
    of Science and Technology Austria, 2021. <a href="https://doi.org/10.15479/AT:ISTA:9056">https://doi.org/10.15479/AT:ISTA:9056</a>.
  ieee: G. F. Osang, “Multi-cover persistence and Delaunay mosaics,” Institute of
    Science and Technology Austria, Klosterneuburg, 2021.
  ista: 'Osang GF. 2021. Multi-cover persistence and Delaunay mosaics. Klosterneuburg:
    Institute of Science and Technology Austria.'
  mla: Osang, Georg F. <i>Multi-Cover Persistence and Delaunay Mosaics</i>. Institute
    of Science and Technology Austria, 2021, doi:<a href="https://doi.org/10.15479/AT:ISTA:9056">10.15479/AT:ISTA:9056</a>.
  short: G.F. Osang, Multi-Cover Persistence and Delaunay Mosaics, Institute of Science
    and Technology Austria, 2021.
date_created: 2021-02-02T14:11:06Z
date_published: 2021-02-01T00:00:00Z
date_updated: 2023-09-07T13:29:01Z
day: '01'
ddc:
- '006'
- '514'
- '516'
degree_awarded: PhD
department:
- _id: HeEd
- _id: GradSch
doi: 10.15479/AT:ISTA:9056
file:
- access_level: closed
  checksum: bcf27986147cab0533b6abadd74e7629
  content_type: application/zip
  creator: patrickd
  date_created: 2021-02-02T14:09:25Z
  date_updated: 2021-02-03T10:37:28Z
  file_id: '9063'
  file_name: thesis_source.zip
  file_size: 13446994
  relation: source_file
- access_level: open_access
  checksum: 9cc8af266579a464385bbe2aff6af606
  content_type: application/pdf
  creator: patrickd
  date_created: 2021-02-02T14:09:18Z
  date_updated: 2021-02-02T14:09:18Z
  file_id: '9064'
  file_name: thesis_pdfA2b.pdf
  file_size: 5210329
  relation: main_file
  success: 1
file_date_updated: 2021-02-03T10:37:28Z
has_accepted_license: '1'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
page: '134'
place: Klosterneuburg
publication_identifier:
  issn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '187'
    relation: part_of_dissertation
    status: public
  - id: '8703'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Herbert
  full_name: Edelsbrunner, Herbert
  id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
  last_name: Edelsbrunner
  orcid: 0000-0002-9823-6833
title: Multi-cover persistence and Delaunay mosaics
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: dissertation
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2021'
...
---
_id: '9073'
abstract:
- lang: eng
  text: The sensory and cognitive abilities of the mammalian neocortex are underpinned
    by intricate columnar and laminar circuits formed from an array of diverse neuronal
    populations. One approach to determining how interactions between these circuit
    components give rise to complex behavior is to investigate the rules by which
    cortical circuits are formed and acquire functionality during development. This
    review summarizes recent research on the development of the neocortex, from genetic
    determination in neural stem cells through to the dynamic role that specific neuronal
    populations play in the earliest circuits of neocortex, and how they contribute
    to emergent function and cognition. While many of these endeavors take advantage
    of model systems, consideration will also be given to advances in our understanding
    of activity in nascent human circuits. Such cross-species perspective is imperative
    when investigating the mechanisms underlying the dysfunction of early neocortical
    circuits in neurodevelopmental disorders, so that one can identify targets amenable
    to therapeutic intervention.
acknowledgement: Work in the I.L.H.-O. laboratory was supported by European Research
  Council Grant ERC-2015-CoG 681577 and German Research Foundation Ha 4466/10-1, Ha4466/11-1,
  Ha4466/12-1, SPP 1665, and SFB 936B5. Work in the S.J.B.B. laboratory was supported
  by Biotechnology and Biological Sciences Research Council BB/P003796/1, Medical
  Research Council MR/K004387/1 and MR/T033320/1, Wellcome Trust 215199/Z/19/Z and
  102386/Z/13/Z, and John Fell Fund. Work in the S.H. laboratory was supported by
  European Research Council Grants ERC-2016-CoG 725780 LinPro and FWF SFB F78. This
  work was supported by National Institutes of Health Grant NIMH 1R01MH110553 to N.V.D.M.G.
  Work in the J.A.C. laboratory was supported by the Ludwig Family Foundation, Simons
  Foundation SFARI Research Award, and National Institutes of Health/National Institute
  of Mental Health R01 MH102365 and R01MH113852. The B.V. laboratory was supported
  by Whitehall Foundation 2017-12-73, National Science Foundation 1736028, National
  Institutes of Health, National Institute of General Medical Sciences R01GM134363-01,
  and Halıcıoğlu Data Science Institute Fellowship. This work was supported by the
  University of California San Diego School of Medicine.
article_processing_charge: No
article_type: original
author:
- first_name: Ileana L.
  full_name: Hanganu-Opatz, Ileana L.
  last_name: Hanganu-Opatz
- first_name: Simon J. B.
  full_name: Butt, Simon J. B.
  last_name: Butt
- first_name: Simon
  full_name: Hippenmeyer, Simon
  id: 37B36620-F248-11E8-B48F-1D18A9856A87
  last_name: Hippenmeyer
  orcid: 0000-0003-2279-1061
- first_name: Natalia V.
  full_name: De Marco García, Natalia V.
  last_name: De Marco García
- first_name: Jessica A.
  full_name: Cardin, Jessica A.
  last_name: Cardin
- first_name: Bradley
  full_name: Voytek, Bradley
  last_name: Voytek
- first_name: Alysson R.
  full_name: Muotri, Alysson R.
  last_name: Muotri
citation:
  ama: Hanganu-Opatz IL, Butt SJB, Hippenmeyer S, et al. The logic of developing neocortical
    circuits in health and disease. <i>The Journal of Neuroscience</i>. 2021;41(5):813-822.
    doi:<a href="https://doi.org/10.1523/jneurosci.1655-20.2020">10.1523/jneurosci.1655-20.2020</a>
  apa: Hanganu-Opatz, I. L., Butt, S. J. B., Hippenmeyer, S., De Marco García, N.
    V., Cardin, J. A., Voytek, B., &#38; Muotri, A. R. (2021). The logic of developing
    neocortical circuits in health and disease. <i>The Journal of Neuroscience</i>.
    Society for Neuroscience. <a href="https://doi.org/10.1523/jneurosci.1655-20.2020">https://doi.org/10.1523/jneurosci.1655-20.2020</a>
  chicago: Hanganu-Opatz, Ileana L., Simon J. B. Butt, Simon Hippenmeyer, Natalia
    V. De Marco García, Jessica A. Cardin, Bradley Voytek, and Alysson R. Muotri.
    “The Logic of Developing Neocortical Circuits in Health and Disease.” <i>The Journal
    of Neuroscience</i>. Society for Neuroscience, 2021. <a href="https://doi.org/10.1523/jneurosci.1655-20.2020">https://doi.org/10.1523/jneurosci.1655-20.2020</a>.
  ieee: I. L. Hanganu-Opatz <i>et al.</i>, “The logic of developing neocortical circuits
    in health and disease,” <i>The Journal of Neuroscience</i>, vol. 41, no. 5. Society
    for Neuroscience, pp. 813–822, 2021.
  ista: Hanganu-Opatz IL, Butt SJB, Hippenmeyer S, De Marco García NV, Cardin JA,
    Voytek B, Muotri AR. 2021. The logic of developing neocortical circuits in health
    and disease. The Journal of Neuroscience. 41(5), 813–822.
  mla: Hanganu-Opatz, Ileana L., et al. “The Logic of Developing Neocortical Circuits
    in Health and Disease.” <i>The Journal of Neuroscience</i>, vol. 41, no. 5, Society
    for Neuroscience, 2021, pp. 813–22, doi:<a href="https://doi.org/10.1523/jneurosci.1655-20.2020">10.1523/jneurosci.1655-20.2020</a>.
  short: I.L. Hanganu-Opatz, S.J.B. Butt, S. Hippenmeyer, N.V. De Marco García, J.A.
    Cardin, B. Voytek, A.R. Muotri, The Journal of Neuroscience 41 (2021) 813–822.
date_created: 2021-02-03T12:23:51Z
date_published: 2021-02-03T00:00:00Z
date_updated: 2023-09-05T14:03:17Z
day: '03'
ddc:
- '570'
department:
- _id: SiHi
doi: 10.1523/jneurosci.1655-20.2020
ec_funded: 1
external_id:
  isi:
  - '000616763400002'
  pmid:
  - '33431633'
file:
- access_level: open_access
  checksum: 578fd7ed1a0aef74bce61bea2d987b33
  content_type: application/pdf
  creator: dernst
  date_created: 2022-05-27T06:59:55Z
  date_updated: 2022-05-27T06:59:55Z
  file_id: '11414'
  file_name: 2021_JourNeuroscience_Hanganu.pdf
  file_size: 1031150
  relation: main_file
  success: 1
file_date_updated: 2022-05-27T06:59:55Z
has_accepted_license: '1'
intvolume: '        41'
isi: 1
issue: '5'
keyword:
- General Neuroscience
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
page: 813-822
pmid: 1
project:
- _id: 260018B0-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '725780'
  name: Principles of Neural Stem Cell Lineage Progression in Cerebral Cortex Development
- _id: 059F6AB4-7A3F-11EA-A408-12923DDC885E
  grant_number: F07805
  name: Molecular Mechanisms of Neural Stem Cell Lineage Progression
publication: The Journal of Neuroscience
publication_identifier:
  eissn:
  - 1529-2401
  issn:
  - 0270-6474
publication_status: published
publisher: Society for Neuroscience
quality_controlled: '1'
scopus_import: '1'
status: public
title: The logic of developing neocortical circuits in health and disease
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 41
year: '2021'
...
---
_id: '9082'
abstract:
- lang: eng
  text: Acquired mutations are sufficiently frequent such that the genome of a single
    cell offers a record of its history of cell divisions. Among more common somatic
    genomic alterations are loss of heterozygosity (LOH). Large LOH events are potentially
    detectable in single cell RNA sequencing (scRNA-seq) datasets as tracts of monoallelic
    expression for constitutionally heterozygous single nucleotide variants (SNVs)
    located among contiguous genes. We identified runs of monoallelic expression,
    consistent with LOH, uniquely distributed throughout the genome in single cell
    brain cortex transcriptomes of F1 hybrids involving different inbred mouse strains.
    We then phylogenetically reconstructed single cell lineages and simultaneously
    identified cell types by corresponding gene expression patterns. Our results are
    consistent with progenitor cells giving rise to multiple cortical cell types through
    stereotyped expansion and distinct waves of neurogenesis. Compared to engineered
    recording systems, LOH events accumulate throughout the genome and across the
    lifetime of an organism, affording tremendous capacity for encoding lineage information
    and increasing resolution for later cell divisions. This approach can conceivably
    be computationally incorporated into scRNA-seq analysis and may be useful for
    organisms where genetic engineering is prohibitive, such as humans.
acknowledgement: "We thank Bill Bolosky, Microsoft Research, for earlier work showing
  proof of concept in TCGA\r\nbulk RNA-seq data. Supported by the Paul G. Allen Frontiers
  Group (University of Washington);\r\nNIH R00HG010152 (Dartmouth); and NÖ Forschung
  und Bildung n[f+b] life science call grant\r\n(C13-002) to SH, and the European
  Research Council (ERC) under the European Union’s\r\nHorizon 2020 research and innovation
  program 725780 LinPro to SH."
article_processing_charge: No
author:
- first_name: Donovan J.
  full_name: Anderson, Donovan J.
  last_name: Anderson
- first_name: Florian
  full_name: Pauler, Florian
  id: 48EA0138-F248-11E8-B48F-1D18A9856A87
  last_name: Pauler
- first_name: Aaron
  full_name: McKenna, Aaron
  last_name: McKenna
- first_name: Jay
  full_name: Shendure, Jay
  last_name: Shendure
- first_name: Simon
  full_name: Hippenmeyer, Simon
  id: 37B36620-F248-11E8-B48F-1D18A9856A87
  last_name: Hippenmeyer
  orcid: 0000-0003-2279-1061
- first_name: Marshall S.
  full_name: Horwitz, Marshall S.
  last_name: Horwitz
citation:
  ama: Anderson DJ, Pauler F, McKenna A, Shendure J, Hippenmeyer S, Horwitz MS. Simultaneous
    identification of brain cell type and lineage via single cell RNA sequencing.
    <i>bioRxiv</i>. doi:<a href="https://doi.org/10.1101/2020.12.31.425016">10.1101/2020.12.31.425016</a>
  apa: Anderson, D. J., Pauler, F., McKenna, A., Shendure, J., Hippenmeyer, S., &#38;
    Horwitz, M. S. (n.d.). Simultaneous identification of brain cell type and lineage
    via single cell RNA sequencing. <i>bioRxiv</i>. Cold Spring Harbor Laboratory.
    <a href="https://doi.org/10.1101/2020.12.31.425016">https://doi.org/10.1101/2020.12.31.425016</a>
  chicago: Anderson, Donovan J., Florian Pauler, Aaron McKenna, Jay Shendure, Simon
    Hippenmeyer, and Marshall S. Horwitz. “Simultaneous Identification of Brain Cell
    Type and Lineage via Single Cell RNA Sequencing.” <i>BioRxiv</i>. Cold Spring
    Harbor Laboratory, n.d. <a href="https://doi.org/10.1101/2020.12.31.425016">https://doi.org/10.1101/2020.12.31.425016</a>.
  ieee: D. J. Anderson, F. Pauler, A. McKenna, J. Shendure, S. Hippenmeyer, and M.
    S. Horwitz, “Simultaneous identification of brain cell type and lineage via single
    cell RNA sequencing,” <i>bioRxiv</i>. Cold Spring Harbor Laboratory.
  ista: Anderson DJ, Pauler F, McKenna A, Shendure J, Hippenmeyer S, Horwitz MS. Simultaneous
    identification of brain cell type and lineage via single cell RNA sequencing.
    bioRxiv, <a href="https://doi.org/10.1101/2020.12.31.425016">10.1101/2020.12.31.425016</a>.
  mla: Anderson, Donovan J., et al. “Simultaneous Identification of Brain Cell Type
    and Lineage via Single Cell RNA Sequencing.” <i>BioRxiv</i>, Cold Spring Harbor
    Laboratory, doi:<a href="https://doi.org/10.1101/2020.12.31.425016">10.1101/2020.12.31.425016</a>.
  short: D.J. Anderson, F. Pauler, A. McKenna, J. Shendure, S. Hippenmeyer, M.S. Horwitz,
    BioRxiv (n.d.).
date_created: 2021-02-04T07:23:23Z
date_published: 2021-01-01T00:00:00Z
date_updated: 2021-02-04T07:29:53Z
day: '01'
department:
- _id: SiHi
doi: 10.1101/2020.12.31.425016
ec_funded: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1101/2020.12.31.425016
month: '01'
oa: 1
oa_version: Preprint
project:
- _id: 260018B0-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '725780'
  name: Principles of Neural Stem Cell Lineage Progression in Cerebral Cortex Development
publication: bioRxiv
publication_status: submitted
publisher: Cold Spring Harbor Laboratory
status: public
title: Simultaneous identification of brain cell type and lineage via single cell
  RNA sequencing
type: preprint
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2021'
...
---
_id: '9093'
abstract:
- lang: eng
  text: We employ the Gross-Pitaevskii equation to study acoustic emission generated
    in a uniform Bose gas by a static impurity. The impurity excites a sound-wave
    packet, which propagates through the gas. We calculate the shape of this wave
    packet in the limit of long wave lengths, and argue that it is possible to extract
    properties of the impurity by observing this shape. We illustrate here this possibility
    for a Bose gas with a trapped impurity atom -- an example of a relevant experimental
    setup. Presented results are general for all one-dimensional systems described
    by the nonlinear Schrödinger equation and can also be used in nonatomic systems,
    e.g., to analyze light propagation in nonlinear optical media. Finally, we calculate
    the shape of the sound-wave packet for a three-dimensional Bose gas assuming a
    spherically symmetric perturbation.
acknowledgement: "We acknowledge fruitful discussions with Dr. Simos Mistakidis regarding
  beyond mean-field\r\neffects in our system. We also thank Prof. Maxim Olshanii for
  valuable suggestions to improve\r\nthe manuscript.O.V.M acknowledges the support
  from the National Science Foundation\r\nthrough grants No. PHY-1402249, No. PHY-1607221,
  and No. PHY-1912542 and the\r\nBinational (US-Israel) Science Foundation through
  grant No. 2015616, as well as by the Israel\r\nScience Foundation (grant No. 1287/17)
  and from the German Aeronautics and Space Administration\r\n(DLR) through Grant
  No. 50WM1957. This work has also received funding from\r\nthe DFG Project No.413495248
  [VO 2437/1-1] and European Union’s Horizon 2020 research\r\nand innovation programme
  under the Marie Skłodowska-Curie Grant Agreement No. 754411\r\n(A. G. V.)"
article_number: '025'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Oleksandr
  full_name: Marchukov, Oleksandr
  last_name: Marchukov
- first_name: Artem
  full_name: Volosniev, Artem
  id: 37D278BC-F248-11E8-B48F-1D18A9856A87
  last_name: Volosniev
  orcid: 0000-0003-0393-5525
citation:
  ama: Marchukov O, Volosniev A. Shape of a sound wave in a weakly-perturbed Bose
    gas. <i>SciPost Physics</i>. 2021;10(2). doi:<a href="https://doi.org/10.21468/scipostphys.10.2.025">10.21468/scipostphys.10.2.025</a>
  apa: Marchukov, O., &#38; Volosniev, A. (2021). Shape of a sound wave in a weakly-perturbed
    Bose gas. <i>SciPost Physics</i>. SciPost Foundation. <a href="https://doi.org/10.21468/scipostphys.10.2.025">https://doi.org/10.21468/scipostphys.10.2.025</a>
  chicago: Marchukov, Oleksandr, and Artem Volosniev. “Shape of a Sound Wave in a
    Weakly-Perturbed Bose Gas.” <i>SciPost Physics</i>. SciPost Foundation, 2021.
    <a href="https://doi.org/10.21468/scipostphys.10.2.025">https://doi.org/10.21468/scipostphys.10.2.025</a>.
  ieee: O. Marchukov and A. Volosniev, “Shape of a sound wave in a weakly-perturbed
    Bose gas,” <i>SciPost Physics</i>, vol. 10, no. 2. SciPost Foundation, 2021.
  ista: Marchukov O, Volosniev A. 2021. Shape of a sound wave in a weakly-perturbed
    Bose gas. SciPost Physics. 10(2), 025.
  mla: Marchukov, Oleksandr, and Artem Volosniev. “Shape of a Sound Wave in a Weakly-Perturbed
    Bose Gas.” <i>SciPost Physics</i>, vol. 10, no. 2, 025, SciPost Foundation, 2021,
    doi:<a href="https://doi.org/10.21468/scipostphys.10.2.025">10.21468/scipostphys.10.2.025</a>.
  short: O. Marchukov, A. Volosniev, SciPost Physics 10 (2021).
date_created: 2021-02-04T12:39:24Z
date_published: 2021-02-03T00:00:00Z
date_updated: 2023-08-07T13:39:37Z
day: '03'
ddc:
- '530'
department:
- _id: MiLe
doi: 10.21468/scipostphys.10.2.025
ec_funded: 1
external_id:
  arxiv:
  - '2004.08075'
  isi:
  - '000646783100027'
file:
- access_level: open_access
  checksum: 9fd614b7ab49999e7267874df2582f7e
  content_type: application/pdf
  creator: dernst
  date_created: 2021-02-09T07:06:22Z
  date_updated: 2021-02-09T07:06:22Z
  file_id: '9105'
  file_name: 2021_SciPostPhysics_Marchukov.pdf
  file_size: 666512
  relation: main_file
  success: 1
file_date_updated: 2021-02-09T07:06:22Z
has_accepted_license: '1'
intvolume: '        10'
isi: 1
issue: '2'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '754411'
  name: ISTplus - Postdoctoral Fellowships
publication: SciPost Physics
publication_identifier:
  issn:
  - 2542-4653
publication_status: published
publisher: SciPost Foundation
quality_controlled: '1'
status: public
title: Shape of a sound wave in a weakly-perturbed Bose gas
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 10
year: '2021'
...
---
_id: '9094'
abstract:
- lang: eng
  text: Dendritic cells (DCs) are crucial for the priming of naive T cells and the
    initiation of adaptive immunity. Priming is initiated at a heterologous cell–cell
    contact, the immunological synapse (IS). While it is established that F-actin
    dynamics regulates signaling at the T cell side of the contact, little is known
    about the cytoskeletal contribution on the DC side. Here, we show that the DC
    actin cytoskeleton is decisive for the formation of a multifocal synaptic structure,
    which correlates with T cell priming efficiency. DC actin at the IS appears in
    transient foci that are dynamized by the WAVE regulatory complex (WRC). The absence
    of the WRC in DCs leads to stabilized contacts with T cells, caused by an increase
    in ICAM1-integrin–mediated cell–cell adhesion. This results in lower numbers of
    activated and proliferating T cells, demonstrating an important role for DC actin
    in the regulation of immune synapse functionality.
article_number: e202006081
article_processing_charge: No
article_type: original
author:
- first_name: Alexander F
  full_name: Leithner, Alexander F
  id: 3B1B77E4-F248-11E8-B48F-1D18A9856A87
  last_name: Leithner
  orcid: 0000-0002-1073-744X
- first_name: LM
  full_name: Altenburger, LM
  last_name: Altenburger
- first_name: R
  full_name: Hauschild, R
  last_name: Hauschild
- first_name: Frank P
  full_name: Assen, Frank P
  id: 3A8E7F24-F248-11E8-B48F-1D18A9856A87
  last_name: Assen
  orcid: 0000-0003-3470-6119
- first_name: K
  full_name: Rottner, K
  last_name: Rottner
- first_name: Stradal
  full_name: TEB, Stradal
  last_name: TEB
- first_name: A
  full_name: Diz-Muñoz, A
  last_name: Diz-Muñoz
- first_name: JV
  full_name: Stein, JV
  last_name: Stein
- first_name: Michael K
  full_name: Sixt, Michael K
  id: 41E9FBEA-F248-11E8-B48F-1D18A9856A87
  last_name: Sixt
  orcid: 0000-0002-6620-9179
citation:
  ama: Leithner AF, Altenburger L, Hauschild R, et al. Dendritic cell actin dynamics
    control contact duration and priming efficiency at the immunological synapse.
    <i>Journal of Cell Biology</i>. 2021;220(4). doi:<a href="https://doi.org/10.1083/jcb.202006081">10.1083/jcb.202006081</a>
  apa: Leithner, A. F., Altenburger, L., Hauschild, R., Assen, F. P., Rottner, K.,
    TEB, S., … Sixt, M. K. (2021). Dendritic cell actin dynamics control contact duration
    and priming efficiency at the immunological synapse. <i>Journal of Cell Biology</i>.
    Rockefeller University Press. <a href="https://doi.org/10.1083/jcb.202006081">https://doi.org/10.1083/jcb.202006081</a>
  chicago: Leithner, Alexander F, LM Altenburger, R Hauschild, Frank P Assen, K Rottner,
    Stradal TEB, A Diz-Muñoz, JV Stein, and Michael K Sixt. “Dendritic Cell Actin
    Dynamics Control Contact Duration and Priming Efficiency at the Immunological
    Synapse.” <i>Journal of Cell Biology</i>. Rockefeller University Press, 2021.
    <a href="https://doi.org/10.1083/jcb.202006081">https://doi.org/10.1083/jcb.202006081</a>.
  ieee: A. F. Leithner <i>et al.</i>, “Dendritic cell actin dynamics control contact
    duration and priming efficiency at the immunological synapse,” <i>Journal of Cell
    Biology</i>, vol. 220, no. 4. Rockefeller University Press, 2021.
  ista: Leithner AF, Altenburger L, Hauschild R, Assen FP, Rottner K, TEB S, Diz-Muñoz
    A, Stein J, Sixt MK. 2021. Dendritic cell actin dynamics control contact duration
    and priming efficiency at the immunological synapse. Journal of Cell Biology.
    220(4), e202006081.
  mla: Leithner, Alexander F., et al. “Dendritic Cell Actin Dynamics Control Contact
    Duration and Priming Efficiency at the Immunological Synapse.” <i>Journal of Cell
    Biology</i>, vol. 220, no. 4, e202006081, Rockefeller University Press, 2021,
    doi:<a href="https://doi.org/10.1083/jcb.202006081">10.1083/jcb.202006081</a>.
  short: A.F. Leithner, L. Altenburger, R. Hauschild, F.P. Assen, K. Rottner, S. TEB,
    A. Diz-Muñoz, J. Stein, M.K. Sixt, Journal of Cell Biology 220 (2021).
date_created: 2021-02-05T10:08:04Z
date_published: 2021-04-05T00:00:00Z
date_updated: 2023-09-05T13:57:53Z
day: '05'
ddc:
- '570'
department:
- _id: MiSi
doi: 10.1083/jcb.202006081
external_id:
  isi:
  - '000626365700001'
  pmid:
  - '33533935'
file:
- access_level: open_access
  checksum: 843ebc153847c8626e13c9c5ce71d533
  content_type: application/pdf
  creator: dernst
  date_created: 2022-05-12T14:16:21Z
  date_updated: 2022-05-12T14:16:21Z
  file_id: '11367'
  file_name: 2021_JournCellBiology_Leithner.pdf
  file_size: 5102328
  relation: main_file
  success: 1
file_date_updated: 2022-05-12T14:16:21Z
has_accepted_license: '1'
intvolume: '       220'
isi: 1
issue: '4'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
pmid: 1
publication: Journal of Cell Biology
publication_identifier:
  eissn:
  - 1540-8140
  issn:
  - 0021-9525
publication_status: published
publisher: Rockefeller University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Dendritic cell actin dynamics control contact duration and priming efficiency
  at the immunological synapse
tmp:
  image: /images/cc_by_nc_sa.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC
    BY-NC-SA 4.0)
  short: CC BY-NC-SA (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 220
year: '2021'
...
