[{"file":[{"relation":"main_file","checksum":"78ffe70c1c88af3856d31ca6b7195a27","creator":"system","date_created":"2018-12-12T10:11:43Z","file_id":"4899","access_level":"open_access","file_size":626804,"file_name":"IST-2016-488-v1+1_20152452.full.pdf","content_type":"application/pdf","date_updated":"2020-07-14T12:45:02Z"}],"publisher":"Royal Society, The","scopus_import":1,"date_created":"2018-12-11T11:52:40Z","file_date_updated":"2020-07-14T12:45:02Z","issue":"1822","author":[{"full_name":"Qi, Qin","id":"3B22D412-F248-11E8-B48F-1D18A9856A87","first_name":"Qin","last_name":"Qi","orcid":"0000-0002-6148-2416"},{"last_name":"Toll Riera","first_name":"Macarena","full_name":"Toll Riera, Macarena"},{"full_name":"Heilbron, Karl","last_name":"Heilbron","first_name":"Karl"},{"full_name":"Preston, Gail","last_name":"Preston","first_name":"Gail"},{"first_name":"R Craig","last_name":"Maclean","full_name":"Maclean, R Craig"}],"date_published":"2016-01-13T00:00:00Z","volume":283,"abstract":[{"text":"Antibiotic resistance carries a fitness cost that must be overcome in order for resistance to persist over the long term. Compensatory mutations that recover the functional defects associated with resistance mutations have been argued to play a key role in overcoming the cost of resistance, but compensatory mutations are expected to be rare relative to generally beneficial mutations that increase fitness, irrespective of antibiotic resistance. Given this asymmetry, population genetics theory predicts that populations should adapt by compensatory mutations when the cost of resistance is large, whereas generally beneficial mutations should drive adaptation when the cost of resistance is small. We tested this prediction by determining the genomic mechanisms underpinning adaptation to antibiotic-free conditions in populations of the pathogenic bacterium Pseudomonas aeruginosa that carry costly antibiotic resistance mutations. Whole-genome sequencing revealed that populations founded by high-cost rifampicin-resistant mutants adapted via compensatory mutations in three genes of the RNA polymerase core enzyme, whereas populations founded by low-cost mutants adapted by generally beneficial mutations, predominantly in the quorum-sensing transcriptional regulator gene lasR. Even though the importance of compensatory evolution in maintaining resistance has been widely recognized, our study shows that the roles of general adaptation in maintaining resistance should not be underestimated and highlights the need to understand how selection at other sites in the genome influences the dynamics of resistance alleles in clinical settings.","lang":"eng"}],"publication":"Proceedings of the Royal Society of London Series B Biological Sciences","year":"2016","language":[{"iso":"eng"}],"day":"13","citation":{"apa":"Qi, Q., Toll Riera, M., Heilbron, K., Preston, G., &#38; Maclean, R. C. (2016). The genomic basis of adaptation to the fitness cost of rifampicin resistance in Pseudomonas aeruginosa. <i>Proceedings of the Royal Society of London Series B Biological Sciences</i>. Royal Society, The. <a href=\"https://doi.org/10.1098/rspb.2015.2452\">https://doi.org/10.1098/rspb.2015.2452</a>","mla":"Qi, Qin, et al. “The Genomic Basis of Adaptation to the Fitness Cost of Rifampicin Resistance in Pseudomonas Aeruginosa.” <i>Proceedings of the Royal Society of London Series B Biological Sciences</i>, vol. 283, no. 1822, 20152452, Royal Society, The, 2016, doi:<a href=\"https://doi.org/10.1098/rspb.2015.2452\">10.1098/rspb.2015.2452</a>.","short":"Q. Qi, M. Toll Riera, K. Heilbron, G. Preston, R.C. Maclean, Proceedings of the Royal Society of London Series B Biological Sciences 283 (2016).","chicago":"Qi, Qin, Macarena Toll Riera, Karl Heilbron, Gail Preston, and R Craig Maclean. “The Genomic Basis of Adaptation to the Fitness Cost of Rifampicin Resistance in Pseudomonas Aeruginosa.” <i>Proceedings of the Royal Society of London Series B Biological Sciences</i>. Royal Society, The, 2016. <a href=\"https://doi.org/10.1098/rspb.2015.2452\">https://doi.org/10.1098/rspb.2015.2452</a>.","ama":"Qi Q, Toll Riera M, Heilbron K, Preston G, Maclean RC. The genomic basis of adaptation to the fitness cost of rifampicin resistance in Pseudomonas aeruginosa. <i>Proceedings of the Royal Society of London Series B Biological Sciences</i>. 2016;283(1822). doi:<a href=\"https://doi.org/10.1098/rspb.2015.2452\">10.1098/rspb.2015.2452</a>","ieee":"Q. Qi, M. Toll Riera, K. Heilbron, G. Preston, and R. C. Maclean, “The genomic basis of adaptation to the fitness cost of rifampicin resistance in Pseudomonas aeruginosa,” <i>Proceedings of the Royal Society of London Series B Biological Sciences</i>, vol. 283, no. 1822. Royal Society, The, 2016.","ista":"Qi Q, Toll Riera M, Heilbron K, Preston G, Maclean RC. 2016. The genomic basis of adaptation to the fitness cost of rifampicin resistance in Pseudomonas aeruginosa. Proceedings of the Royal Society of London Series B Biological Sciences. 283(1822), 20152452."},"tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"title":"The genomic basis of adaptation to the fitness cost of rifampicin resistance in Pseudomonas aeruginosa","pubrep_id":"488","status":"public","type":"journal_article","doi":"10.1098/rspb.2015.2452","intvolume":"       283","_id":"1552","quality_controlled":"1","acknowledgement":"We thank the High-Throughput Genomics Group at the Wellcome Trust Centre for Human Genetics funded by Wellcome\r\nTrust grant reference 090532/Z/09/Z and Medical Research Council Hub grant no. G0900747 91070 for generation of the high-throughput sequencing data. We thank Wook Kim and two anonymous reviewers for their constructive feedback on previous versions of our manuscript.","department":[{"_id":"ToBo"}],"has_accepted_license":"1","article_number":"20152452","oa_version":"Published Version","month":"01","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","publist_id":"5619","oa":1,"publication_status":"published","ddc":["570"],"date_updated":"2021-01-12T06:51:33Z"},{"publisher":"Springer","citation":{"apa":"Abe, M., Fuchsbauer, G., Groth, J., Haralambiev, K., &#38; Ohkubo, M. (2016). Structure preserving signatures and commitments to group elements. <i>Journal of Cryptology</i>. Springer. <a href=\"https://doi.org/10.1007/s00145-014-9196-7\">https://doi.org/10.1007/s00145-014-9196-7</a>","mla":"Abe, Masayuki, et al. “Structure Preserving Signatures and Commitments to Group Elements.” <i>Journal of Cryptology</i>, vol. 29, no. 2, Springer, 2016, pp. 363–421, doi:<a href=\"https://doi.org/10.1007/s00145-014-9196-7\">10.1007/s00145-014-9196-7</a>.","chicago":"Abe, Masayuki, Georg Fuchsbauer, Jens Groth, Kristiyan Haralambiev, and Miyako Ohkubo. “Structure Preserving Signatures and Commitments to Group Elements.” <i>Journal of Cryptology</i>. Springer, 2016. <a href=\"https://doi.org/10.1007/s00145-014-9196-7\">https://doi.org/10.1007/s00145-014-9196-7</a>.","ama":"Abe M, Fuchsbauer G, Groth J, Haralambiev K, Ohkubo M. Structure preserving signatures and commitments to group elements. <i>Journal of Cryptology</i>. 2016;29(2):363-421. doi:<a href=\"https://doi.org/10.1007/s00145-014-9196-7\">10.1007/s00145-014-9196-7</a>","short":"M. Abe, G. Fuchsbauer, J. Groth, K. Haralambiev, M. Ohkubo, Journal of Cryptology 29 (2016) 363–421.","ieee":"M. Abe, G. Fuchsbauer, J. Groth, K. Haralambiev, and M. Ohkubo, “Structure preserving signatures and commitments to group elements,” <i>Journal of Cryptology</i>, vol. 29, no. 2. Springer, pp. 363–421, 2016.","ista":"Abe M, Fuchsbauer G, Groth J, Haralambiev K, Ohkubo M. 2016. Structure preserving signatures and commitments to group elements. Journal of Cryptology. 29(2), 363–421."},"title":"Structure preserving signatures and commitments to group elements","scopus_import":1,"status":"public","type":"journal_article","doi":"10.1007/s00145-014-9196-7","date_created":"2018-12-11T11:52:54Z","_id":"1592","page":"363 - 421","intvolume":"        29","acknowledgement":"The authors would like to thank the anonymous reviewers of this paper. We also would like to express our appreciation to the program committee and the anonymous reviewers for CRYPTO 2010. The first author thanks Sherman S. M. Chow for his comment on group signatures in Sect. 7.1.","quality_controlled":"1","department":[{"_id":"KrPi"}],"issue":"2","author":[{"full_name":"Abe, Masayuki","last_name":"Abe","first_name":"Masayuki"},{"id":"46B4C3EE-F248-11E8-B48F-1D18A9856A87","full_name":"Fuchsbauer, Georg","last_name":"Fuchsbauer","first_name":"Georg"},{"full_name":"Groth, Jens","last_name":"Groth","first_name":"Jens"},{"full_name":"Haralambiev, Kristiyan","last_name":"Haralambiev","first_name":"Kristiyan"},{"full_name":"Ohkubo, Miyako","first_name":"Miyako","last_name":"Ohkubo"}],"volume":29,"abstract":[{"lang":"eng","text":"A modular approach to constructing cryptographic protocols leads to simple designs but often inefficient instantiations. On the other hand, ad hoc constructions may yield efficient protocols at the cost of losing conceptual simplicity. We suggest a new design paradigm, structure-preserving cryptography, that provides a way to construct modular protocols with reasonable efficiency while retaining conceptual simplicity. A cryptographic scheme over a bilinear group is called structure-preserving if its public inputs and outputs consist of elements from the bilinear groups and their consistency can be verified by evaluating pairing-product equations. As structure-preserving schemes smoothly interoperate with each other, they are useful as building blocks in modular design of cryptographic applications. This paper introduces structure-preserving commitment and signature schemes over bilinear groups with several desirable properties. The commitment schemes include homomorphic, trapdoor and length-reducing commitments to group elements, and the structure-preserving signature schemes are the first ones that yield constant-size signatures on multiple group elements. A structure-preserving signature scheme is called automorphic if the public keys lie in the message space, which cannot be achieved by compressing inputs via a cryptographic hash function, as this would destroy the mathematical structure we are trying to preserve. Automorphic signatures can be used for building certification chains underlying privacy-preserving protocols. Among a vast number of applications of structure-preserving protocols, we present an efficient round-optimal blind-signature scheme and a group signature scheme with an efficient and concurrently secure protocol for enrolling new members."}],"date_published":"2016-04-01T00:00:00Z","month":"04","oa_version":"None","publication":"Journal of Cryptology","publist_id":"5579","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","day":"01","year":"2016","language":[{"iso":"eng"}],"publication_status":"published","date_updated":"2021-01-12T06:51:49Z"},{"quality_controlled":"1","acknowledgement":"This work was supported by the Boehringer Ingelheim Fonds, the European Research Council (ERC StG 281556), and a START Award of the Austrian Science Foundation (FWF). We thank Robert Hauschild, Anne Reversat, and Jack Merrin for valuable input and the Imaging Facility of IST Austria for excellent support.","department":[{"_id":"MiSi"}],"external_id":{"pmid":["26921962"]},"doi":"10.1016/bs.mie.2015.11.004","intvolume":"       570","page":"567 - 581","_id":"1597","title":"Quantitative analysis of dendritic cell haptotaxis","type":"journal_article","status":"public","citation":{"ista":"Schwarz J, Sixt MK. 2016. Quantitative analysis of dendritic cell haptotaxis. Methods in Enzymology. 570, 567–581.","ieee":"J. Schwarz and M. K. Sixt, “Quantitative analysis of dendritic cell haptotaxis,” <i>Methods in Enzymology</i>, vol. 570. Elsevier, pp. 567–581, 2016.","mla":"Schwarz, Jan, and Michael K. Sixt. “Quantitative Analysis of Dendritic Cell Haptotaxis.” <i>Methods in Enzymology</i>, vol. 570, Elsevier, 2016, pp. 567–81, doi:<a href=\"https://doi.org/10.1016/bs.mie.2015.11.004\">10.1016/bs.mie.2015.11.004</a>.","apa":"Schwarz, J., &#38; Sixt, M. K. (2016). Quantitative analysis of dendritic cell haptotaxis. <i>Methods in Enzymology</i>. Elsevier. <a href=\"https://doi.org/10.1016/bs.mie.2015.11.004\">https://doi.org/10.1016/bs.mie.2015.11.004</a>","short":"J. Schwarz, M.K. Sixt, Methods in Enzymology 570 (2016) 567–581.","ama":"Schwarz J, Sixt MK. Quantitative analysis of dendritic cell haptotaxis. <i>Methods in Enzymology</i>. 2016;570:567-581. doi:<a href=\"https://doi.org/10.1016/bs.mie.2015.11.004\">10.1016/bs.mie.2015.11.004</a>","chicago":"Schwarz, Jan, and Michael K Sixt. “Quantitative Analysis of Dendritic Cell Haptotaxis.” <i>Methods in Enzymology</i>. Elsevier, 2016. <a href=\"https://doi.org/10.1016/bs.mie.2015.11.004\">https://doi.org/10.1016/bs.mie.2015.11.004</a>."},"article_processing_charge":"No","acknowledged_ssus":[{"_id":"Bio"}],"publication_status":"published","date_updated":"2021-01-12T06:51:51Z","month":"01","oa_version":"None","publist_id":"5573","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","project":[{"call_identifier":"FP7","grant_number":"281556","name":"Cytoskeletal force generation and force transduction of migrating leukocytes (EU)","_id":"25A603A2-B435-11E9-9278-68D0E5697425"},{"call_identifier":"FWF","grant_number":"Y 564-B12","_id":"25A8E5EA-B435-11E9-9278-68D0E5697425","name":"Cytoskeletal force generation and transduction of leukocytes (FWF)"}],"date_created":"2018-12-11T11:52:56Z","article_type":"original","scopus_import":1,"pmid":1,"publisher":"Elsevier","ec_funded":1,"publication":"Methods in Enzymology","language":[{"iso":"eng"}],"year":"2016","day":"01","author":[{"first_name":"Jan","last_name":"Schwarz","full_name":"Schwarz, Jan","id":"346C1EC6-F248-11E8-B48F-1D18A9856A87"},{"orcid":"0000-0002-6620-9179","first_name":"Michael K","last_name":"Sixt","full_name":"Sixt, Michael K","id":"41E9FBEA-F248-11E8-B48F-1D18A9856A87"}],"date_published":"2016-01-01T00:00:00Z","abstract":[{"lang":"eng","text":"Chemokines are the main guidance cues directing leukocyte migration. Opposed to early assumptions, chemokines do not necessarily act as soluble cues but are often immobilized within tissues, e.g., dendritic cell migration toward lymphatic vessels is guided by a haptotactic gradient of the chemokine CCL21. Controlled assay systems to quantitatively study haptotaxis in vitro are still missing. In this chapter, we describe an in vitro haptotaxis assay optimized for the unique properties of dendritic cells. The chemokine CCL21 is immobilized in a bioactive state, using laser-assisted protein adsorption by photobleaching. The cells follow this immobilized CCL21 gradient in a haptotaxis chamber, which provides three dimensionally confined migration conditions."}],"volume":570},{"article_type":"original","date_created":"2018-12-11T11:52:57Z","project":[{"grant_number":"281556","call_identifier":"FP7","name":"Cytoskeletal force generation and force transduction of migrating leukocytes (EU)","_id":"25A603A2-B435-11E9-9278-68D0E5697425"},{"_id":"25A76F58-B435-11E9-9278-68D0E5697425","name":"Stromal Cell-immune Cell Interactions in Health and Disease","grant_number":"289720","call_identifier":"FP7"},{"grant_number":"Y 564-B12","call_identifier":"FWF","name":"Cytoskeletal force generation and transduction of leukocytes (FWF)","_id":"25A8E5EA-B435-11E9-9278-68D0E5697425"}],"scopus_import":1,"main_file_link":[{"url":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583642/","open_access":"1"}],"pmid":1,"publisher":"American Association for the Advancement of Science","ec_funded":1,"publication":"Science","year":"2016","language":[{"iso":"eng"}],"day":"08","author":[{"last_name":"Kiermaier","first_name":"Eva","orcid":"0000-0001-6165-5738","id":"3EB04B78-F248-11E8-B48F-1D18A9856A87","full_name":"Kiermaier, Eva"},{"full_name":"Moussion, Christine","id":"3356F664-F248-11E8-B48F-1D18A9856A87","last_name":"Moussion","first_name":"Christine"},{"full_name":"Veldkamp, Christopher","first_name":"Christopher","last_name":"Veldkamp"},{"first_name":"Rita","last_name":"Gerardy  Schahn","full_name":"Gerardy  Schahn, Rita"},{"id":"4C7D837E-F248-11E8-B48F-1D18A9856A87","full_name":"De Vries, Ingrid","first_name":"Ingrid","last_name":"De Vries"},{"first_name":"Larry","last_name":"Williams","full_name":"Williams, Larry"},{"last_name":"Chaffee","first_name":"Gary","full_name":"Chaffee, Gary"},{"last_name":"Phillips","first_name":"Andrew","full_name":"Phillips, Andrew"},{"first_name":"Friedrich","last_name":"Freiberger","full_name":"Freiberger, Friedrich"},{"full_name":"Imre, Richard","last_name":"Imre","first_name":"Richard"},{"full_name":"Taleski, Deni","last_name":"Taleski","first_name":"Deni"},{"full_name":"Payne, Richard","first_name":"Richard","last_name":"Payne"},{"last_name":"Braun","first_name":"Asolina","full_name":"Braun, Asolina"},{"last_name":"Förster","first_name":"Reinhold","full_name":"Förster, Reinhold"},{"first_name":"Karl","last_name":"Mechtler","full_name":"Mechtler, Karl"},{"full_name":"Mühlenhoff, Martina","last_name":"Mühlenhoff","first_name":"Martina"},{"full_name":"Volkman, Brian","first_name":"Brian","last_name":"Volkman"},{"orcid":"0000-0002-6620-9179","first_name":"Michael K","last_name":"Sixt","full_name":"Sixt, Michael K","id":"41E9FBEA-F248-11E8-B48F-1D18A9856A87"}],"date_published":"2016-01-08T00:00:00Z","abstract":[{"text":"The addition of polysialic acid to N- and/or O-linked glycans, referred to as polysialylation, is a rare posttranslational modification that is mainly known to control the developmental plasticity of the nervous system. Here we show that CCR7, the central chemokine receptor controlling immune cell trafficking to secondary lymphatic organs, carries polysialic acid. This modification is essential for the recognition of the CCR7 ligand CCL21. As a consequence, dendritic cell trafficking is abrogated in polysialyltransferase-deficient mice, manifesting as disturbed lymph node homeostasis and unresponsiveness to inflammatory stimuli. Structure-function analysis of chemokine-receptor interactions reveals that CCL21 adopts an autoinhibited conformation, which is released upon interaction with polysialic acid. Thus, we describe a glycosylation-mediated immune cell trafficking disorder and its mechanistic basis.\r\n","lang":"eng"}],"volume":351,"issue":"6269","quality_controlled":"1","acknowledgement":"We thank S. Schüchner and E. Ogris for kindly providing the antibody to GFP, M. Helmbrecht and A. Huber for providing Nrp2−/− mice, the IST Scientific Support Facilities for excellent services, and J. Renkawitz and K. Vaahtomeri for critically reading the manuscript. ","department":[{"_id":"MiSi"}],"external_id":{"pmid":["26657283"]},"doi":"10.1126/science.aad0512","intvolume":"       351","_id":"1599","page":"186 - 190","title":"Polysialylation controls dendritic cell trafficking by regulating chemokine recognition","type":"journal_article","status":"public","article_processing_charge":"No","citation":{"ieee":"E. Kiermaier <i>et al.</i>, “Polysialylation controls dendritic cell trafficking by regulating chemokine recognition,” <i>Science</i>, vol. 351, no. 6269. American Association for the Advancement of Science, pp. 186–190, 2016.","ista":"Kiermaier E, Moussion C, Veldkamp C, Gerardy  Schahn R, de Vries I, Williams L, Chaffee G, Phillips A, Freiberger F, Imre R, Taleski D, Payne R, Braun A, Förster R, Mechtler K, Mühlenhoff M, Volkman B, Sixt MK. 2016. Polysialylation controls dendritic cell trafficking by regulating chemokine recognition. Science. 351(6269), 186–190.","mla":"Kiermaier, Eva, et al. “Polysialylation Controls Dendritic Cell Trafficking by Regulating Chemokine Recognition.” <i>Science</i>, vol. 351, no. 6269, American Association for the Advancement of Science, 2016, pp. 186–90, doi:<a href=\"https://doi.org/10.1126/science.aad0512\">10.1126/science.aad0512</a>.","apa":"Kiermaier, E., Moussion, C., Veldkamp, C., Gerardy  Schahn, R., de Vries, I., Williams, L., … Sixt, M. K. (2016). Polysialylation controls dendritic cell trafficking by regulating chemokine recognition. <i>Science</i>. American Association for the Advancement of Science. <a href=\"https://doi.org/10.1126/science.aad0512\">https://doi.org/10.1126/science.aad0512</a>","chicago":"Kiermaier, Eva, Christine Moussion, Christopher Veldkamp, Rita Gerardy  Schahn, Ingrid de Vries, Larry Williams, Gary Chaffee, et al. “Polysialylation Controls Dendritic Cell Trafficking by Regulating Chemokine Recognition.” <i>Science</i>. American Association for the Advancement of Science, 2016. <a href=\"https://doi.org/10.1126/science.aad0512\">https://doi.org/10.1126/science.aad0512</a>.","ama":"Kiermaier E, Moussion C, Veldkamp C, et al. Polysialylation controls dendritic cell trafficking by regulating chemokine recognition. <i>Science</i>. 2016;351(6269):186-190. doi:<a href=\"https://doi.org/10.1126/science.aad0512\">10.1126/science.aad0512</a>","short":"E. Kiermaier, C. Moussion, C. Veldkamp, R. Gerardy  Schahn, I. de Vries, L. Williams, G. Chaffee, A. Phillips, F. Freiberger, R. Imre, D. Taleski, R. Payne, A. Braun, R. Förster, K. Mechtler, M. Mühlenhoff, B. Volkman, M.K. Sixt, Science 351 (2016) 186–190."},"acknowledged_ssus":[{"_id":"SSU"}],"publication_status":"published","oa":1,"date_updated":"2021-01-12T06:51:52Z","month":"01","oa_version":"Submitted Version","publist_id":"5570","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87"},{"year":"2016","language":[{"iso":"eng"}],"day":"01","publication":"Annales Henri Poincare","ec_funded":1,"issue":"7","date_published":"2016-07-01T00:00:00Z","abstract":[{"text":"We show that the Anderson model has a transition from localization to delocalization at exactly 2 dimensional growth rate on antitrees with normalized edge weights which are certain discrete graphs. The kinetic part has a one-dimensional structure allowing a description through transfer matrices which involve some Schur complement. For such operators we introduce the notion of having one propagating channel and extend theorems from the theory of one-dimensional Jacobi operators that relate the behavior of transfer matrices with the spectrum. These theorems are then applied to the considered model. In essence, in a certain energy region the kinetic part averages the random potentials along shells and the transfer matrices behave similar as for a one-dimensional operator with random potential of decaying variance. At d dimensional growth for d&gt;2 this effective decay is strong enough to obtain absolutely continuous spectrum, whereas for some uniform d dimensional growth with d&lt;2 one has pure point spectrum in this energy region. At exactly uniform 2 dimensional growth also some singular continuous spectrum appears, at least at small disorder. As a corollary we also obtain a change from singular spectrum (d≤2) to absolutely continuous spectrum (d≥3) for random operators of the type rΔdr+λ on ℤd, where r is an orthogonal radial projection, Δd the discrete adjacency operator (Laplacian) on ℤd and λ a random potential. ","lang":"eng"}],"volume":17,"author":[{"orcid":"0000-0001-8255-3968","last_name":"Sadel","first_name":"Christian","id":"4760E9F8-F248-11E8-B48F-1D18A9856A87","full_name":"Sadel, Christian"}],"project":[{"grant_number":"291734","call_identifier":"FP7","name":"International IST Postdoc Fellowship Programme","_id":"25681D80-B435-11E9-9278-68D0E5697425"}],"date_created":"2018-12-11T11:53:00Z","main_file_link":[{"url":"http://arxiv.org/abs/1501.04287","open_access":"1"}],"publisher":"Birkhäuser","scopus_import":1,"publist_id":"5558","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","month":"07","oa_version":"Preprint","date_updated":"2021-01-12T06:51:58Z","oa":1,"publication_status":"published","intvolume":"        17","page":"1631 - 1675","_id":"1608","doi":"10.1007/s00023-015-0456-3","department":[{"_id":"LaEr"}],"quality_controlled":"1","citation":{"ista":"Sadel C. 2016. Anderson transition at 2 dimensional growth rate on antitrees and spectral theory for operators with one propagating channel. Annales Henri Poincare. 17(7), 1631–1675.","ieee":"C. Sadel, “Anderson transition at 2 dimensional growth rate on antitrees and spectral theory for operators with one propagating channel,” <i>Annales Henri Poincare</i>, vol. 17, no. 7. Birkhäuser, pp. 1631–1675, 2016.","short":"C. Sadel, Annales Henri Poincare 17 (2016) 1631–1675.","chicago":"Sadel, Christian. “Anderson Transition at 2 Dimensional Growth Rate on Antitrees and Spectral Theory for Operators with One Propagating Channel.” <i>Annales Henri Poincare</i>. Birkhäuser, 2016. <a href=\"https://doi.org/10.1007/s00023-015-0456-3\">https://doi.org/10.1007/s00023-015-0456-3</a>.","ama":"Sadel C. Anderson transition at 2 dimensional growth rate on antitrees and spectral theory for operators with one propagating channel. <i>Annales Henri Poincare</i>. 2016;17(7):1631-1675. doi:<a href=\"https://doi.org/10.1007/s00023-015-0456-3\">10.1007/s00023-015-0456-3</a>","mla":"Sadel, Christian. “Anderson Transition at 2 Dimensional Growth Rate on Antitrees and Spectral Theory for Operators with One Propagating Channel.” <i>Annales Henri Poincare</i>, vol. 17, no. 7, Birkhäuser, 2016, pp. 1631–75, doi:<a href=\"https://doi.org/10.1007/s00023-015-0456-3\">10.1007/s00023-015-0456-3</a>.","apa":"Sadel, C. (2016). Anderson transition at 2 dimensional growth rate on antitrees and spectral theory for operators with one propagating channel. <i>Annales Henri Poincare</i>. Birkhäuser. <a href=\"https://doi.org/10.1007/s00023-015-0456-3\">https://doi.org/10.1007/s00023-015-0456-3</a>"},"type":"journal_article","status":"public","title":"Anderson transition at 2 dimensional growth rate on antitrees and spectral theory for operators with one propagating channel"},{"scopus_import":1,"title":"CSP for binary conservative relational structures","type":"journal_article","status":"public","citation":{"ieee":"A. Kazda, “CSP for binary conservative relational structures,” <i>Algebra Universalis</i>, vol. 75, no. 1. Springer, pp. 75–84, 2016.","ista":"Kazda A. 2016. CSP for binary conservative relational structures. Algebra Universalis. 75(1), 75–84.","ama":"Kazda A. CSP for binary conservative relational structures. <i>Algebra Universalis</i>. 2016;75(1):75-84. doi:<a href=\"https://doi.org/10.1007/s00012-015-0358-8\">10.1007/s00012-015-0358-8</a>","chicago":"Kazda, Alexandr. “CSP for Binary Conservative Relational Structures.” <i>Algebra Universalis</i>. Springer, 2016. <a href=\"https://doi.org/10.1007/s00012-015-0358-8\">https://doi.org/10.1007/s00012-015-0358-8</a>.","short":"A. Kazda, Algebra Universalis 75 (2016) 75–84.","apa":"Kazda, A. (2016). CSP for binary conservative relational structures. <i>Algebra Universalis</i>. Springer. <a href=\"https://doi.org/10.1007/s00012-015-0358-8\">https://doi.org/10.1007/s00012-015-0358-8</a>","mla":"Kazda, Alexandr. “CSP for Binary Conservative Relational Structures.” <i>Algebra Universalis</i>, vol. 75, no. 1, Springer, 2016, pp. 75–84, doi:<a href=\"https://doi.org/10.1007/s00012-015-0358-8\">10.1007/s00012-015-0358-8</a>."},"main_file_link":[{"open_access":"1","url":"http://arxiv.org/abs/1112.1099"}],"publisher":"Springer","quality_controlled":"1","department":[{"_id":"VlKo"}],"doi":"10.1007/s00012-015-0358-8","date_created":"2018-12-11T11:53:01Z","intvolume":"        75","page":"75 - 84","_id":"1612","author":[{"id":"3B32BAA8-F248-11E8-B48F-1D18A9856A87","full_name":"Kazda, Alexandr","last_name":"Kazda","first_name":"Alexandr"}],"date_published":"2016-02-01T00:00:00Z","abstract":[{"lang":"eng","text":"We prove that whenever A is a 3-conservative relational structure with only binary and unary relations,then the algebra of polymorphisms of A either has no Taylor operation (i.e.,CSP(A)is NP-complete),or it generates an SD(∧) variety (i.e.,CSP(A)has bounded width)."}],"volume":75,"issue":"1","publication_status":"published","oa":1,"date_updated":"2021-01-12T06:52:00Z","month":"02","publication":"Algebra Universalis","oa_version":"Preprint","language":[{"iso":"eng"}],"year":"2016","day":"01","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","publist_id":"5554"},{"_id":"1319","page":"3806 - 3816","date_created":"2018-12-11T11:51:21Z","doi":"10.1145/2858036.2858354","department":[{"_id":"BeBi"}],"acknowledgement":"We  thank  Damian  Karrer,   Rocco  Ghielmini  and  Jemin\r\nHwangbo for their help in our initial explorations. We would\r\nlike to thank Christian Schumacher for creating the video and\r\nC\r\n ́\r\necile Edwards-Rietmann for providing the voiceover. Mau-\r\nrizio Nitti helped us in designing our 3D characters. We thank\r\nChiara Daraio for insightful discussions on material proper-\r\nties and 3D printing.   We also thank the CHI reviewers for\r\ntheir feedback and guidance. Fabrizio Pece was supported by\r\nan ETH/Marie Curie fellowship (FEL-3314-1).","quality_controlled":"1","publisher":"ACM","citation":{"ista":"Bächer M, Hepp B, Pece F, Kry P, Bickel B, Thomaszewski B, Hilliges O. 2016. DefSense: computational design of customized deformable input devices. CHI: Conference on Human Factors in Computing Systems, 3806–3816.","ieee":"M. Bächer <i>et al.</i>, “DefSense: computational design of customized deformable input devices,” presented at the CHI: Conference on Human Factors in Computing Systems, San Jose, California, USA, 2016, pp. 3806–3816.","chicago":"Bächer, Moritz, Benjamin Hepp, Fabrizio Pece, Paul Kry, Bernd Bickel, Bernhard Thomaszewski, and Otmar Hilliges. “DefSense: Computational Design of Customized Deformable Input Devices,” 3806–16. ACM, 2016. <a href=\"https://doi.org/10.1145/2858036.2858354\">https://doi.org/10.1145/2858036.2858354</a>.","short":"M. Bächer, B. Hepp, F. Pece, P. Kry, B. Bickel, B. Thomaszewski, O. Hilliges, in:, ACM, 2016, pp. 3806–3816.","ama":"Bächer M, Hepp B, Pece F, et al. DefSense: computational design of customized deformable input devices. In: ACM; 2016:3806-3816. doi:<a href=\"https://doi.org/10.1145/2858036.2858354\">10.1145/2858036.2858354</a>","apa":"Bächer, M., Hepp, B., Pece, F., Kry, P., Bickel, B., Thomaszewski, B., &#38; Hilliges, O. (2016). DefSense: computational design of customized deformable input devices (pp. 3806–3816). Presented at the CHI: Conference on Human Factors in Computing Systems, San Jose, California, USA: ACM. <a href=\"https://doi.org/10.1145/2858036.2858354\">https://doi.org/10.1145/2858036.2858354</a>","mla":"Bächer, Moritz, et al. <i>DefSense: Computational Design of Customized Deformable Input Devices</i>. ACM, 2016, pp. 3806–16, doi:<a href=\"https://doi.org/10.1145/2858036.2858354\">10.1145/2858036.2858354</a>."},"type":"conference","status":"public","title":"DefSense: computational design of customized deformable input devices","scopus_import":1,"user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","publist_id":"5951","day":"07","language":[{"iso":"eng"}],"year":"2016","month":"05","oa_version":"None","date_updated":"2021-01-12T06:49:51Z","publication_status":"published","conference":{"location":"San Jose, California, USA","end_date":"2016-05-12","start_date":"2016-05-07","name":"CHI: Conference on Human Factors in Computing Systems"},"abstract":[{"text":"We present a novel optimization-based algorithm for the design and fabrication of customized, deformable input devices, capable of continuously sensing their deformation. We propose to embed piezoresistive sensing elements into flexible 3D printed objects. These sensing elements are then utilized to recover rich and natural user interactions at runtime. Designing such objects is a challenging and hard problem if attempted manually for all but the simplest geometries and deformations. Our method simultaneously optimizes the internal routing of the sensing elements and computes a mapping from low-level sensor readings to user-specified outputs in order to minimize reconstruction error. We demonstrate the power and flexibility of the approach by designing and fabricating a set of flexible input devices. Our results indicate that the optimization-based design greatly outperforms manual routings in terms of reconstruction accuracy and thus interaction fidelity.","lang":"eng"}],"date_published":"2016-05-07T00:00:00Z","author":[{"first_name":"Moritz","last_name":"Bächer","full_name":"Bächer, Moritz"},{"first_name":"Benjamin","last_name":"Hepp","full_name":"Hepp, Benjamin"},{"last_name":"Pece","first_name":"Fabrizio","full_name":"Pece, Fabrizio"},{"first_name":"Paul","last_name":"Kry","full_name":"Kry, Paul"},{"id":"49876194-F248-11E8-B48F-1D18A9856A87","full_name":"Bickel, Bernd","orcid":"0000-0001-6511-9385","first_name":"Bernd","last_name":"Bickel"},{"last_name":"Thomaszewski","first_name":"Bernhard","full_name":"Thomaszewski, Bernhard"},{"last_name":"Hilliges","first_name":"Otmar","full_name":"Hilliges, Otmar"}]},{"ec_funded":1,"day":"28","language":[{"iso":"eng"}],"year":"2016","volume":"2016-July","abstract":[{"text":"In recent years, several biomolecular systems have been shown to be scale-invariant (SI), i.e. to show the same output dynamics when exposed to geometrically scaled input signals (u → pu, p &gt; 0) after pre-adaptation to accordingly scaled constant inputs. In this article, we show that SI systems-as well as systems invariant with respect to other input transformations-can realize nonlinear differential operators: when excited by inputs obeying functional forms characteristic for a given class of invariant systems, the systems' outputs converge to constant values directly quantifying the speed of the input.","lang":"eng"}],"date_published":"2016-07-28T00:00:00Z","author":[{"last_name":"Lang","first_name":"Moritz","id":"29E0800A-F248-11E8-B48F-1D18A9856A87","full_name":"Lang, Moritz"},{"full_name":"Sontag, Eduardo","last_name":"Sontag","first_name":"Eduardo"}],"file_date_updated":"2020-07-14T12:44:43Z","project":[{"call_identifier":"FP7","grant_number":"291734","name":"International IST Postdoc Fellowship Programme","_id":"25681D80-B435-11E9-9278-68D0E5697425"}],"date_created":"2018-12-11T11:51:21Z","scopus_import":1,"publisher":"IEEE","file":[{"file_name":"IST-2017-810-v1+1_root.pdf","access_level":"local","file_size":539166,"date_updated":"2020-07-14T12:44:43Z","content_type":"application/pdf","creator":"system","date_created":"2018-12-12T10:16:17Z","relation":"main_file","checksum":"7219432b43defc62a0d45f48d4ce6a19","file_id":"5203"}],"ddc":["003","621"],"date_updated":"2021-01-12T06:49:51Z","publication_status":"published","conference":{"location":"Boston, MA, USA","start_date":"2016-07-06","name":"ACC: American Control Conference","end_date":"2016-07-08"},"user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","publist_id":"5950","oa_version":"Preprint","month":"07","article_number":"7526722","has_accepted_license":"1","department":[{"_id":"CaGu"},{"_id":"GaTk"}],"acknowledgement":"The research leading to these results has received funding from the People Programme (Marie Curie Actions) of the European Union's Seventh Framework Programme (FP7/2007-2013) under REA grant agreement n° [291734]. Work supported in part by grants AFOSR FA9550-14-1-0060 and NIH 1R01GM100473.","quality_controlled":"1","_id":"1320","doi":"10.1109/ACC.2016.7526722","type":"conference","status":"public","pubrep_id":"810","title":"Scale-invariant systems realize nonlinear differential operators","citation":{"ieee":"M. Lang and E. Sontag, “Scale-invariant systems realize nonlinear differential operators,” presented at the ACC: American Control Conference, Boston, MA, USA, 2016, vol. 2016–July.","ista":"Lang M, Sontag E. 2016. Scale-invariant systems realize nonlinear differential operators. ACC: American Control Conference vol. 2016–July, 7526722.","ama":"Lang M, Sontag E. Scale-invariant systems realize nonlinear differential operators. In: Vol 2016-July. IEEE; 2016. doi:<a href=\"https://doi.org/10.1109/ACC.2016.7526722\">10.1109/ACC.2016.7526722</a>","chicago":"Lang, Moritz, and Eduardo Sontag. “Scale-Invariant Systems Realize Nonlinear Differential Operators,” Vol. 2016–July. IEEE, 2016. <a href=\"https://doi.org/10.1109/ACC.2016.7526722\">https://doi.org/10.1109/ACC.2016.7526722</a>.","short":"M. Lang, E. Sontag, in:, IEEE, 2016.","apa":"Lang, M., &#38; Sontag, E. (2016). Scale-invariant systems realize nonlinear differential operators (Vol. 2016–July). Presented at the ACC: American Control Conference, Boston, MA, USA: IEEE. <a href=\"https://doi.org/10.1109/ACC.2016.7526722\">https://doi.org/10.1109/ACC.2016.7526722</a>","mla":"Lang, Moritz, and Eduardo Sontag. <i>Scale-Invariant Systems Realize Nonlinear Differential Operators</i>. Vol. 2016–July, 7526722, IEEE, 2016, doi:<a href=\"https://doi.org/10.1109/ACC.2016.7526722\">10.1109/ACC.2016.7526722</a>."}},{"has_accepted_license":"1","oa_version":"Submitted Version","month":"10","publist_id":"5949","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","related_material":{"record":[{"id":"323","relation":"dissertation_contains","status":"public"}]},"oa":1,"publication_status":"published","ddc":["570"],"date_updated":"2024-03-25T23:30:09Z","article_processing_charge":"No","citation":{"ieee":"A. F. Leithner <i>et al.</i>, “Diversified actin protrusions promote environmental exploration but are dispensable for locomotion of leukocytes,” <i>Nature Cell Biology</i>, vol. 18. Nature Publishing Group, pp. 1253–1259, 2016.","ista":"Leithner AF, Eichner A, Müller J, Reversat A, Brown M, Schwarz J, Merrin J, De Gorter D, Schur FK, Bayerl J, de Vries I, Wieser S, Hauschild R, Lai F, Moser M, Kerjaschki D, Rottner K, Small V, Stradal T, Sixt MK. 2016. Diversified actin protrusions promote environmental exploration but are dispensable for locomotion of leukocytes. Nature Cell Biology. 18, 1253–1259.","chicago":"Leithner, Alexander F, Alexander Eichner, Jan Müller, Anne Reversat, Markus Brown, Jan Schwarz, Jack Merrin, et al. “Diversified Actin Protrusions Promote Environmental Exploration but Are Dispensable for Locomotion of Leukocytes.” <i>Nature Cell Biology</i>. Nature Publishing Group, 2016. <a href=\"https://doi.org/10.1038/ncb3426\">https://doi.org/10.1038/ncb3426</a>.","short":"A.F. Leithner, A. Eichner, J. Müller, A. Reversat, M. Brown, J. Schwarz, J. Merrin, D. De Gorter, F.K. Schur, J. Bayerl, I. de Vries, S. Wieser, R. Hauschild, F. Lai, M. Moser, D. Kerjaschki, K. Rottner, V. Small, T. Stradal, M.K. Sixt, Nature Cell Biology 18 (2016) 1253–1259.","ama":"Leithner AF, Eichner A, Müller J, et al. Diversified actin protrusions promote environmental exploration but are dispensable for locomotion of leukocytes. <i>Nature Cell Biology</i>. 2016;18:1253-1259. doi:<a href=\"https://doi.org/10.1038/ncb3426\">10.1038/ncb3426</a>","mla":"Leithner, Alexander F., et al. “Diversified Actin Protrusions Promote Environmental Exploration but Are Dispensable for Locomotion of Leukocytes.” <i>Nature Cell Biology</i>, vol. 18, Nature Publishing Group, 2016, pp. 1253–59, doi:<a href=\"https://doi.org/10.1038/ncb3426\">10.1038/ncb3426</a>.","apa":"Leithner, A. F., Eichner, A., Müller, J., Reversat, A., Brown, M., Schwarz, J., … Sixt, M. K. (2016). Diversified actin protrusions promote environmental exploration but are dispensable for locomotion of leukocytes. <i>Nature Cell Biology</i>. Nature Publishing Group. <a href=\"https://doi.org/10.1038/ncb3426\">https://doi.org/10.1038/ncb3426</a>"},"acknowledged_ssus":[{"_id":"SSU"}],"title":"Diversified actin protrusions promote environmental exploration but are dispensable for locomotion of leukocytes","tmp":{"image":"/images/cc_by_nc_sa.png","short":"CC BY-NC-SA (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode","name":"Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)"},"type":"journal_article","status":"public","doi":"10.1038/ncb3426","page":"1253 - 1259","_id":"1321","intvolume":"        18","acknowledgement":"This work was supported by the German Research Foundation (DFG) Priority Program SP 1464 to T.E.B.S. and M.S., and European Research Council (ERC GA 281556) and Human Frontiers Program grants to M.S.\r\nService Units of IST Austria for excellent technical support.","quality_controlled":"1","department":[{"_id":"MiSi"},{"_id":"NanoFab"},{"_id":"Bio"}],"file_date_updated":"2020-07-14T12:44:43Z","author":[{"id":"3B1B77E4-F248-11E8-B48F-1D18A9856A87","full_name":"Leithner, Alexander F","orcid":"0000-0002-1073-744X","last_name":"Leithner","first_name":"Alexander F"},{"full_name":"Eichner, Alexander","id":"4DFA52AE-F248-11E8-B48F-1D18A9856A87","first_name":"Alexander","last_name":"Eichner"},{"last_name":"Müller","first_name":"Jan","id":"AD07FDB4-0F61-11EA-8158-C4CC64CEAA8D","full_name":"Müller, Jan"},{"full_name":"Reversat, Anne","id":"35B76592-F248-11E8-B48F-1D18A9856A87","first_name":"Anne","last_name":"Reversat","orcid":"0000-0003-0666-8928"},{"first_name":"Markus","last_name":"Brown","id":"3DAB9AFC-F248-11E8-B48F-1D18A9856A87","full_name":"Brown, Markus"},{"first_name":"Jan","last_name":"Schwarz","id":"346C1EC6-F248-11E8-B48F-1D18A9856A87","full_name":"Schwarz, Jan"},{"orcid":"0000-0001-5145-4609","last_name":"Merrin","first_name":"Jack","full_name":"Merrin, Jack","id":"4515C308-F248-11E8-B48F-1D18A9856A87"},{"last_name":"De Gorter","first_name":"David","full_name":"De Gorter, David"},{"full_name":"Schur, Florian","id":"48AD8942-F248-11E8-B48F-1D18A9856A87","first_name":"Florian","last_name":"Schur","orcid":"0000-0003-4790-8078"},{"first_name":"Jonathan","last_name":"Bayerl","full_name":"Bayerl, Jonathan"},{"first_name":"Ingrid","last_name":"De Vries","id":"4C7D837E-F248-11E8-B48F-1D18A9856A87","full_name":"De Vries, Ingrid"},{"orcid":"0000-0002-2670-2217","first_name":"Stefan","last_name":"Wieser","id":"355AA5A0-F248-11E8-B48F-1D18A9856A87","full_name":"Wieser, Stefan"},{"orcid":"0000-0001-9843-3522","first_name":"Robert","last_name":"Hauschild","id":"4E01D6B4-F248-11E8-B48F-1D18A9856A87","full_name":"Hauschild, Robert"},{"last_name":"Lai","first_name":"Frank","full_name":"Lai, Frank"},{"last_name":"Moser","first_name":"Markus","full_name":"Moser, Markus"},{"last_name":"Kerjaschki","first_name":"Dontscho","full_name":"Kerjaschki, Dontscho"},{"full_name":"Rottner, Klemens","first_name":"Klemens","last_name":"Rottner"},{"full_name":"Small, Victor","first_name":"Victor","last_name":"Small"},{"last_name":"Stradal","first_name":"Theresia","full_name":"Stradal, Theresia"},{"first_name":"Michael K","last_name":"Sixt","orcid":"0000-0002-6620-9179","id":"41E9FBEA-F248-11E8-B48F-1D18A9856A87","full_name":"Sixt, Michael K"}],"abstract":[{"text":"Most migrating cells extrude their front by the force of actin polymerization. Polymerization requires an initial nucleation step, which is mediated by factors establishing either parallel filaments in the case of filopodia or branched filaments that form the branched lamellipodial network. Branches are considered essential for regular cell motility and are initiated by the Arp2/3 complex, which in turn is activated by nucleation-promoting factors of the WASP and WAVE families. Here we employed rapid amoeboid crawling leukocytes and found that deletion of the WAVE complex eliminated actin branching and thus lamellipodia formation. The cells were left with parallel filaments at the leading edge, which translated, depending on the differentiation status of the cell, into a unipolar pointed cell shape or cells with multiple filopodia. Remarkably, unipolar cells migrated with increased speed and enormous directional persistence, while they were unable to turn towards chemotactic gradients. Cells with multiple filopodia retained chemotactic activity but their migration was progressively impaired with increasing geometrical complexity of the extracellular environment. These findings establish that diversified leading edge protrusions serve as explorative structures while they slow down actual locomotion.","lang":"eng"}],"volume":18,"date_published":"2016-10-24T00:00:00Z","publication":"Nature Cell Biology","day":"24","language":[{"iso":"eng"}],"year":"2016","ec_funded":1,"publisher":"Nature Publishing Group","file":[{"file_id":"7844","date_created":"2020-05-14T16:33:46Z","creator":"dernst","relation":"main_file","checksum":"e1411cb7c99a2d9089c178a6abef25e7","date_updated":"2020-07-14T12:44:43Z","content_type":"application/pdf","file_name":"2018_NatureCell_Leithner.pdf","access_level":"open_access","file_size":4433280}],"scopus_import":1,"project":[{"call_identifier":"FP7","grant_number":"281556","_id":"25A603A2-B435-11E9-9278-68D0E5697425","name":"Cytoskeletal force generation and force transduction of migrating leukocytes (EU)"}],"article_type":"original","date_created":"2018-12-11T11:51:21Z"},{"title":"Asymmetric power boosts extortion in an economic experiment","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"pubrep_id":"716","status":"public","type":"journal_article","citation":{"ista":"Hilbe C, Hagel K, Milinski M. 2016. Asymmetric power boosts extortion in an economic experiment. PLoS One. 11(10), e0163867.","ieee":"C. Hilbe, K. Hagel, and M. Milinski, “Asymmetric power boosts extortion in an economic experiment,” <i>PLoS One</i>, vol. 11, no. 10. Public Library of Science, 2016.","mla":"Hilbe, Christian, et al. “Asymmetric Power Boosts Extortion in an Economic Experiment.” <i>PLoS One</i>, vol. 11, no. 10, e0163867, Public Library of Science, 2016, doi:<a href=\"https://doi.org/10.1371/journal.pone.0163867\">10.1371/journal.pone.0163867</a>.","apa":"Hilbe, C., Hagel, K., &#38; Milinski, M. (2016). Asymmetric power boosts extortion in an economic experiment. <i>PLoS One</i>. Public Library of Science. <a href=\"https://doi.org/10.1371/journal.pone.0163867\">https://doi.org/10.1371/journal.pone.0163867</a>","short":"C. Hilbe, K. Hagel, M. Milinski, PLoS One 11 (2016).","chicago":"Hilbe, Christian, Kristin Hagel, and Manfred Milinski. “Asymmetric Power Boosts Extortion in an Economic Experiment.” <i>PLoS One</i>. Public Library of Science, 2016. <a href=\"https://doi.org/10.1371/journal.pone.0163867\">https://doi.org/10.1371/journal.pone.0163867</a>.","ama":"Hilbe C, Hagel K, Milinski M. Asymmetric power boosts extortion in an economic experiment. <i>PLoS One</i>. 2016;11(10). doi:<a href=\"https://doi.org/10.1371/journal.pone.0163867\">10.1371/journal.pone.0163867</a>"},"quality_controlled":"1","acknowledgement":"CH was funded by the Schrödinger program of the Austrian Science Fund (FWF) J3475. ","department":[{"_id":"KrCh"}],"doi":"10.1371/journal.pone.0163867","intvolume":"        11","_id":"1322","article_number":"e0163867","has_accepted_license":"1","publication_status":"published","oa":1,"date_updated":"2023-02-23T14:11:27Z","ddc":["004","006"],"month":"10","oa_version":"Published Version","related_material":{"record":[{"status":"public","id":"9867","relation":"research_data"},{"status":"public","relation":"research_data","id":"9868"}]},"user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","publist_id":"5948","scopus_import":1,"publisher":"Public Library of Science","file":[{"relation":"main_file","checksum":"6b33e394003dfe8b4ca6be1858aaa8e3","creator":"system","date_created":"2018-12-12T10:08:08Z","file_id":"4668","access_level":"open_access","file_size":2077905,"file_name":"IST-2016-716-v1+1_journal.pone.0163867.PDF","content_type":"application/pdf","date_updated":"2020-07-14T12:44:44Z"}],"date_created":"2018-12-11T11:51:22Z","author":[{"full_name":"Hilbe, Christian","id":"2FDF8F3C-F248-11E8-B48F-1D18A9856A87","first_name":"Christian","last_name":"Hilbe","orcid":"0000-0001-5116-955X"},{"last_name":"Hagel","first_name":"Kristin","full_name":"Hagel, Kristin"},{"last_name":"Milinski","first_name":"Manfred","full_name":"Milinski, Manfred"}],"date_published":"2016-10-04T00:00:00Z","abstract":[{"text":"Direct reciprocity is a major mechanism for the evolution of cooperation. Several classical studies have suggested that humans should quickly learn to adopt reciprocal strategies to establish mutual cooperation in repeated interactions. On the other hand, the recently discovered theory of ZD strategies has found that subjects who use extortionate strategies are able to exploit and subdue cooperators. Although such extortioners have been predicted to succeed in any population of adaptive opponents, theoretical follow-up studies questioned whether extortion can evolve in reality. However, most of these studies presumed that individuals have similar strategic possibilities and comparable outside options, whereas asymmetries are ubiquitous in real world applications. Here we show with a model and an economic experiment that extortionate strategies readily emerge once subjects differ in their strategic power. Our experiment combines a repeated social dilemma with asymmetric partner choice. In our main treatment there is one randomly chosen group member who is unilaterally allowed to exchange one of the other group members after every ten rounds of the social dilemma. We find that this asymmetric replacement opportunity generally promotes cooperation, but often the resulting payoff distribution reflects the underlying power structure. Almost half of the subjects in a better strategic position turn into extortioners, who quickly proceed to exploit their peers. By adapting their cooperation probabilities consistent with ZD theory, extortioners force their co-players to cooperate without being similarly cooperative themselves. Comparison to non-extortionate players under the same conditions indicates a substantial net gain to extortion. Our results thus highlight how power asymmetries can endanger mutually beneficial interactions, and transform them into exploitative relationships. In particular, our results indicate that the extortionate strategies predicted from ZD theory could play a more prominent role in our daily interactions than previously thought.","lang":"eng"}],"volume":11,"file_date_updated":"2020-07-14T12:44:44Z","issue":"10","publication":"PLoS One","language":[{"iso":"eng"}],"year":"2016","day":"04"},{"citation":{"ieee":"N. Vyleta, C. Borges Merjane, and P. M. Jonas, “Plasticity-dependent, full detonation at hippocampal mossy fiber–CA3 pyramidal neuron synapses,” <i>eLife</i>, vol. 5. eLife Sciences Publications, 2016.","ista":"Vyleta N, Borges Merjane C, Jonas PM. 2016. Plasticity-dependent, full detonation at hippocampal mossy fiber–CA3 pyramidal neuron synapses. eLife. 5, e17977.","short":"N. Vyleta, C. Borges Merjane, P.M. Jonas, ELife 5 (2016).","ama":"Vyleta N, Borges Merjane C, Jonas PM. Plasticity-dependent, full detonation at hippocampal mossy fiber–CA3 pyramidal neuron synapses. <i>eLife</i>. 2016;5. doi:<a href=\"https://doi.org/10.7554/eLife.17977\">10.7554/eLife.17977</a>","chicago":"Vyleta, Nicholas, Carolina Borges Merjane, and Peter M Jonas. “Plasticity-Dependent, Full Detonation at Hippocampal Mossy Fiber–CA3 Pyramidal Neuron Synapses.” <i>ELife</i>. eLife Sciences Publications, 2016. <a href=\"https://doi.org/10.7554/eLife.17977\">https://doi.org/10.7554/eLife.17977</a>.","mla":"Vyleta, Nicholas, et al. “Plasticity-Dependent, Full Detonation at Hippocampal Mossy Fiber–CA3 Pyramidal Neuron Synapses.” <i>ELife</i>, vol. 5, e17977, eLife Sciences Publications, 2016, doi:<a href=\"https://doi.org/10.7554/eLife.17977\">10.7554/eLife.17977</a>.","apa":"Vyleta, N., Borges Merjane, C., &#38; Jonas, P. M. (2016). Plasticity-dependent, full detonation at hippocampal mossy fiber–CA3 pyramidal neuron synapses. <i>ELife</i>. eLife Sciences Publications. <a href=\"https://doi.org/10.7554/eLife.17977\">https://doi.org/10.7554/eLife.17977</a>"},"acknowledged_ssus":[{"_id":"M-Shop"},{"_id":"PreCl"}],"tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"title":"Plasticity-dependent, full detonation at hippocampal mossy fiber–CA3 pyramidal neuron synapses","type":"journal_article","status":"public","pubrep_id":"715","doi":"10.7554/eLife.17977","_id":"1323","intvolume":"         5","quality_controlled":"1","department":[{"_id":"PeJo"}],"has_accepted_license":"1","article_number":"e17977","oa_version":"Published Version","month":"10","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","publist_id":"5947","oa":1,"publication_status":"published","date_updated":"2023-02-21T10:34:24Z","ddc":["571","572"],"publisher":"eLife Sciences Publications","file":[{"file_id":"5257","checksum":"a7201280c571bed88ebd459ce5ce6a47","relation":"main_file","creator":"system","date_created":"2018-12-12T10:17:05Z","content_type":"application/pdf","date_updated":"2020-07-14T12:44:44Z","file_size":1477891,"access_level":"open_access","file_name":"IST-2016-715-v1+1_e17977-download.pdf"}],"scopus_import":1,"date_created":"2018-12-11T11:51:22Z","project":[{"call_identifier":"FP7","grant_number":"268548","name":"Nanophysiology of fast-spiking, parvalbumin-expressing GABAergic interneurons","_id":"25C0F108-B435-11E9-9278-68D0E5697425"},{"name":"Biophysics and circuit function of a giant cortical glumatergic synapse","_id":"25B7EB9E-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","grant_number":"692692"}],"file_date_updated":"2020-07-14T12:44:44Z","author":[{"id":"36C4978E-F248-11E8-B48F-1D18A9856A87","full_name":"Vyleta, Nicholas","last_name":"Vyleta","first_name":"Nicholas"},{"id":"4305C450-F248-11E8-B48F-1D18A9856A87","full_name":"Borges Merjane, Carolina","last_name":"Borges Merjane","first_name":"Carolina","orcid":"0000-0003-0005-401X"},{"last_name":"Jonas","first_name":"Peter M","orcid":"0000-0001-5001-4804","id":"353C1B58-F248-11E8-B48F-1D18A9856A87","full_name":"Jonas, Peter M"}],"abstract":[{"lang":"eng","text":"Mossy fiber synapses on CA3 pyramidal cells are 'conditional detonators' that reliably discharge postsynaptic targets. The 'conditional' nature implies that burst activity in dentate gyrus granule cells is required for detonation. Whether single unitary excitatory postsynaptic potentials (EPSPs) trigger spikes in CA3 neurons remains unknown. Mossy fiber synapses exhibit both pronounced short-term facilitation and uniquely large post-tetanic potentiation (PTP). We tested whether PTP could convert mossy fiber synapses from subdetonator into detonator mode, using a recently developed method to selectively and noninvasively stimulate individual presynaptic terminals in rat brain slices. Unitary EPSPs failed to initiate a spike in CA3 neurons under control conditions, but reliably discharged them after induction of presynaptic short-term plasticity. Remarkably, PTP switched mossy fiber synapses into full detonators for tens of seconds. Plasticity-dependent detonation may be critical for efficient coding, storage, and recall of information in the granule cell–CA3 cell network."}],"volume":5,"date_published":"2016-10-25T00:00:00Z","publication":"eLife","day":"25","year":"2016","language":[{"iso":"eng"}],"ec_funded":1},{"publication_status":"published","conference":{"end_date":"2016-06-17","name":"ICAPS: International Conference on Automated Planning and Scheduling","start_date":"2016-06-12","location":"London, United Kingdom"},"date_updated":"2021-01-12T06:49:53Z","ec_funded":1,"oa_version":"None","month":"01","publication":"Proceedings of the Twenty-Sixth International Conference on International Conference on Automated Planning and Scheduling","day":"01","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","publist_id":"5946","year":"2016","language":[{"iso":"eng"}],"author":[{"orcid":"0000-0002-4561-241X","first_name":"Krishnendu","last_name":"Chatterjee","full_name":"Chatterjee, Krishnendu","id":"2E5DCA20-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Chmelik","first_name":"Martin","full_name":"Chmelik, Martin","id":"3624234E-F248-11E8-B48F-1D18A9856A87"}],"abstract":[{"lang":"eng","text":"DEC-POMDPs extend POMDPs to a multi-agent setting, where several agents operate in an uncertain environment independently to achieve a joint objective. DEC-POMDPs have been studied with finite-horizon and infinite-horizon discounted-sum objectives, and there exist solvers both for exact and approximate solutions. In this work we consider Goal-DEC-POMDPs, where given a set of target states, the objective is to ensure that the target set is reached with minimal cost. We consider the indefinite-horizon (infinite-horizon with either discounted-sum, or undiscounted-sum, where absorbing goal states have zero-cost) problem. We present a new and novel method to solve the problem that extends methods for finite-horizon DEC-POMDPs and the RTDP-Bel approach for POMDPs. We present experimental results on several examples, and show that our approach presents promising results. Copyright "}],"volume":"2016-January","date_published":"2016-01-01T00:00:00Z","quality_controlled":"1","department":[{"_id":"KrCh"}],"date_created":"2018-12-11T11:51:22Z","project":[{"name":"Modern Graph Algorithmic Techniques in Formal Verification","_id":"2584A770-B435-11E9-9278-68D0E5697425","grant_number":"P 23499-N23","call_identifier":"FWF"},{"name":"Quantitative Graph Games: Theory and Applications","_id":"2581B60A-B435-11E9-9278-68D0E5697425","grant_number":"279307","call_identifier":"FP7"},{"call_identifier":"FWF","grant_number":"S 11407_N23","name":"Rigorous Systems Engineering","_id":"25832EC2-B435-11E9-9278-68D0E5697425"}],"page":"88 - 96","_id":"1324","scopus_import":1,"title":"Indefinite-horizon reachability in Goal-DEC-POMDPs","type":"conference","status":"public","publisher":"AAAI Press","main_file_link":[{"url":"http://www.aaai.org/ocs/index.php/ICAPS/ICAPS16/paper/view/12999"}],"citation":{"mla":"Chatterjee, Krishnendu, and Martin Chmelik. “Indefinite-Horizon Reachability in Goal-DEC-POMDPs.” <i>Proceedings of the Twenty-Sixth International Conference on International Conference on Automated Planning and Scheduling</i>, vol. 2016–January, AAAI Press, 2016, pp. 88–96.","apa":"Chatterjee, K., &#38; Chmelik, M. (2016). Indefinite-horizon reachability in Goal-DEC-POMDPs. In <i>Proceedings of the Twenty-Sixth International Conference on International Conference on Automated Planning and Scheduling</i> (Vol. 2016–January, pp. 88–96). London, United Kingdom: AAAI Press.","short":"K. Chatterjee, M. Chmelik, in:, Proceedings of the Twenty-Sixth International Conference on International Conference on Automated Planning and Scheduling, AAAI Press, 2016, pp. 88–96.","chicago":"Chatterjee, Krishnendu, and Martin Chmelik. “Indefinite-Horizon Reachability in Goal-DEC-POMDPs.” In <i>Proceedings of the Twenty-Sixth International Conference on International Conference on Automated Planning and Scheduling</i>, 2016–January:88–96. AAAI Press, 2016.","ama":"Chatterjee K, Chmelik M. Indefinite-horizon reachability in Goal-DEC-POMDPs. In: <i>Proceedings of the Twenty-Sixth International Conference on International Conference on Automated Planning and Scheduling</i>. Vol 2016-January. AAAI Press; 2016:88-96.","ista":"Chatterjee K, Chmelik M. 2016. Indefinite-horizon reachability in Goal-DEC-POMDPs. Proceedings of the Twenty-Sixth International Conference on International Conference on Automated Planning and Scheduling. ICAPS: International Conference on Automated Planning and Scheduling vol. 2016–January, 88–96.","ieee":"K. Chatterjee and M. Chmelik, “Indefinite-horizon reachability in Goal-DEC-POMDPs,” in <i>Proceedings of the Twenty-Sixth International Conference on International Conference on Automated Planning and Scheduling</i>, London, United Kingdom, 2016, vol. 2016–January, pp. 88–96."}},{"day":"01","language":[{"iso":"eng"}],"year":"2016","ec_funded":1,"file_date_updated":"2020-07-14T12:44:44Z","author":[{"full_name":"Brázdil, Tomáš","first_name":"Tomáš","last_name":"Brázdil"},{"full_name":"Forejt, Vojtěch","first_name":"Vojtěch","last_name":"Forejt"},{"full_name":"Kučera, Antonín","first_name":"Antonín","last_name":"Kučera"},{"first_name":"Petr","last_name":"Novotny","id":"3CC3B868-F248-11E8-B48F-1D18A9856A87","full_name":"Novotny, Petr"}],"abstract":[{"text":"We study graphs and two-player games in which rewards are assigned to states, and the goal of the players is to satisfy or dissatisfy certain property of the generated outcome, given as a mean payoff property. Since the notion of mean-payoff does not reflect possible fluctuations from the mean-payoff along a run, we propose definitions and algorithms for capturing the stability of the system, and give algorithms for deciding if a given mean payoff and stability objective can be ensured in the system.","lang":"eng"}],"volume":59,"date_published":"2016-08-01T00:00:00Z","date_created":"2018-12-11T11:51:23Z","project":[{"call_identifier":"FP7","grant_number":"291734","_id":"25681D80-B435-11E9-9278-68D0E5697425","name":"International IST Postdoc Fellowship Programme"}],"publisher":"Schloss Dagstuhl - Leibniz-Zentrum für Informatik","file":[{"file_name":"IST-2016-665-v1+1_Forejt_et_al__Stability_in_graphs_and_games.pdf","file_size":553648,"access_level":"open_access","date_updated":"2020-07-14T12:44:44Z","content_type":"application/pdf","creator":"system","date_created":"2018-12-12T10:16:40Z","checksum":"3c2dc6ab0358f8aa8f7aa7d6c1293159","relation":"main_file","file_id":"5229"}],"scopus_import":1,"month":"08","oa_version":"Published Version","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","publist_id":"5944","oa":1,"publication_status":"published","conference":{"start_date":"2016-08-23","name":"CONCUR: Concurrency Theory","end_date":"2016-08-26","location":"Quebec City, Canada"},"date_updated":"2021-01-12T06:49:53Z","ddc":["004"],"has_accepted_license":"1","alternative_title":["LIPIcs"],"article_number":"10","doi":"10.4230/LIPIcs.CONCUR.2016.10","_id":"1325","intvolume":"        59","acknowledgement":"The work has been supported by the Czech Science Foundation, grant No. 15-17564S, by EPSRC grant\r\nEP/M023656/1, and by the People Programme (Marie Curie Actions) of the European Union’s Seventh\r\nFramework Programme (FP7/2007-2013) under REA grant agreement no [291734]","quality_controlled":"1","department":[{"_id":"KrCh"}],"citation":{"mla":"Brázdil, Tomáš, et al. <i>Stability in Graphs and Games</i>. Vol. 59, 10, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2016, doi:<a href=\"https://doi.org/10.4230/LIPIcs.CONCUR.2016.10\">10.4230/LIPIcs.CONCUR.2016.10</a>.","apa":"Brázdil, T., Forejt, V., Kučera, A., &#38; Novotný, P. (2016). Stability in graphs and games (Vol. 59). Presented at the CONCUR: Concurrency Theory, Quebec City, Canada: Schloss Dagstuhl - Leibniz-Zentrum für Informatik. <a href=\"https://doi.org/10.4230/LIPIcs.CONCUR.2016.10\">https://doi.org/10.4230/LIPIcs.CONCUR.2016.10</a>","short":"T. Brázdil, V. Forejt, A. Kučera, P. Novotný, in:, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2016.","chicago":"Brázdil, Tomáš, Vojtěch Forejt, Antonín Kučera, and Petr Novotný. “Stability in Graphs and Games,” Vol. 59. Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2016. <a href=\"https://doi.org/10.4230/LIPIcs.CONCUR.2016.10\">https://doi.org/10.4230/LIPIcs.CONCUR.2016.10</a>.","ama":"Brázdil T, Forejt V, Kučera A, Novotný P. Stability in graphs and games. In: Vol 59. Schloss Dagstuhl - Leibniz-Zentrum für Informatik; 2016. doi:<a href=\"https://doi.org/10.4230/LIPIcs.CONCUR.2016.10\">10.4230/LIPIcs.CONCUR.2016.10</a>","ista":"Brázdil T, Forejt V, Kučera A, Novotný P. 2016. Stability in graphs and games. CONCUR: Concurrency Theory, LIPIcs, vol. 59, 10.","ieee":"T. Brázdil, V. Forejt, A. Kučera, and P. Novotný, “Stability in graphs and games,” presented at the CONCUR: Concurrency Theory, Quebec City, Canada, 2016, vol. 59."},"title":"Stability in graphs and games","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"status":"public","type":"conference","pubrep_id":"665"},{"date_created":"2018-12-11T11:51:23Z","project":[{"_id":"25681D80-B435-11E9-9278-68D0E5697425","name":"International IST Postdoc Fellowship Programme","call_identifier":"FP7","grant_number":"291734"}],"main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/1607.00678"}],"publisher":"Springer","scopus_import":1,"language":[{"iso":"eng"}],"year":"2016","day":"22","ec_funded":1,"date_published":"2016-09-22T00:00:00Z","abstract":[{"lang":"eng","text":"Energy Markov Decision Processes (EMDPs) are finite-state Markov decision processes where each transition is assigned an integer counter update and a rational payoff. An EMDP configuration is a pair s(n), where s is a control state and n is the current counter value. The configurations are changed by performing transitions in the standard way. We consider the problem of computing a safe strategy (i.e., a strategy that keeps the counter non-negative) which maximizes the expected mean payoff. "}],"volume":9938,"author":[{"full_name":"Brázdil, Tomáš","last_name":"Brázdil","first_name":"Tomáš"},{"first_name":"Antonín","last_name":"Kučera","full_name":"Kučera, Antonín"},{"full_name":"Novotny, Petr","id":"3CC3B868-F248-11E8-B48F-1D18A9856A87","first_name":"Petr","last_name":"Novotny"}],"intvolume":"      9938","page":"32 - 49","_id":"1326","doi":"10.1007/978-3-319-46520-3_3","department":[{"_id":"KrCh"}],"quality_controlled":"1","acknowledgement":"The research was funded by the Czech Science Foundation Grant No. P202/12/G061 and by the People Programme (Marie Curie Actions) of the European Union’s Seventh Framework Programme (FP7/2007-2013) under REA grant agreement no [291734].","citation":{"ista":"Brázdil T, Kučera A, Novotný P. 2016. Optimizing the expected mean payoff in Energy Markov Decision Processes. ATVA: Automated Technology for Verification and Analysis, LNCS, vol. 9938, 32–49.","ieee":"T. Brázdil, A. Kučera, and P. Novotný, “Optimizing the expected mean payoff in Energy Markov Decision Processes,” presented at the ATVA: Automated Technology for Verification and Analysis, Chiba, Japan, 2016, vol. 9938, pp. 32–49.","mla":"Brázdil, Tomáš, et al. <i>Optimizing the Expected Mean Payoff in Energy Markov Decision Processes</i>. Vol. 9938, Springer, 2016, pp. 32–49, doi:<a href=\"https://doi.org/10.1007/978-3-319-46520-3_3\">10.1007/978-3-319-46520-3_3</a>.","apa":"Brázdil, T., Kučera, A., &#38; Novotný, P. (2016). Optimizing the expected mean payoff in Energy Markov Decision Processes (Vol. 9938, pp. 32–49). Presented at the ATVA: Automated Technology for Verification and Analysis, Chiba, Japan: Springer. <a href=\"https://doi.org/10.1007/978-3-319-46520-3_3\">https://doi.org/10.1007/978-3-319-46520-3_3</a>","ama":"Brázdil T, Kučera A, Novotný P. Optimizing the expected mean payoff in Energy Markov Decision Processes. In: Vol 9938. Springer; 2016:32-49. doi:<a href=\"https://doi.org/10.1007/978-3-319-46520-3_3\">10.1007/978-3-319-46520-3_3</a>","chicago":"Brázdil, Tomáš, Antonín Kučera, and Petr Novotný. “Optimizing the Expected Mean Payoff in Energy Markov Decision Processes,” 9938:32–49. Springer, 2016. <a href=\"https://doi.org/10.1007/978-3-319-46520-3_3\">https://doi.org/10.1007/978-3-319-46520-3_3</a>.","short":"T. Brázdil, A. Kučera, P. Novotný, in:, Springer, 2016, pp. 32–49."},"type":"conference","status":"public","title":"Optimizing the expected mean payoff in Energy Markov Decision Processes","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","publist_id":"5943","month":"09","oa_version":"Preprint","date_updated":"2021-01-12T06:49:53Z","conference":{"location":"Chiba, Japan","end_date":"2016-10-20","start_date":"2016-10-17","name":"ATVA: Automated Technology for Verification and Analysis"},"oa":1,"publication_status":"published","alternative_title":["LNCS"]},{"date_updated":"2021-01-12T06:49:54Z","ec_funded":1,"oa":1,"publication_status":"published","conference":{"end_date":"2016-05-13","name":"AAMAS: Autonomous Agents & Multiagent Systems","start_date":"2016-05-09","location":"Singapore"},"publist_id":"5942","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","day":"01","year":"2016","language":[{"iso":"eng"}],"oa_version":"Preprint","month":"01","publication":"Proceedings of the 15th International Conference on Autonomous Agents and Multiagent Systems","abstract":[{"lang":"eng","text":"We consider partially observable Markov decision processes (POMDPs) with a set of target states and positive integer costs associated with every transition. The traditional optimization objective (stochastic shortest path) asks to minimize the expected total cost until the target set is reached. We extend the traditional framework of POMDPs to model energy consumption, which represents a hard constraint. The energy levels may increase and decrease with transitions, and the hard constraint requires that the energy level must remain positive in all steps till the target is reached. First, we present a novel algorithm for solving POMDPs with energy levels, developing on existing POMDP solvers and using RTDP as its main method. Our second contribution is related to policy representation. For larger POMDP instances the policies computed by existing solvers are too large to be understandable. We present an automated procedure based on machine learning techniques that automatically extracts important decisions of the policy allowing us to compute succinct human readable policies. Finally, we show experimentally that our algorithm performs well and computes succinct policies on a number of POMDP instances from the literature that were naturally enhanced with energy levels. "}],"date_published":"2016-01-01T00:00:00Z","author":[{"first_name":"Tomáš","last_name":"Brázdil","full_name":"Brázdil, Tomáš"},{"full_name":"Chatterjee, Krishnendu","id":"2E5DCA20-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-4561-241X","first_name":"Krishnendu","last_name":"Chatterjee"},{"full_name":"Chmelik, Martin","id":"3624234E-F248-11E8-B48F-1D18A9856A87","first_name":"Martin","last_name":"Chmelik"},{"last_name":"Gupta","first_name":"Anchit","full_name":"Gupta, Anchit"},{"full_name":"Novotny, Petr","id":"3CC3B868-F248-11E8-B48F-1D18A9856A87","last_name":"Novotny","first_name":"Petr"}],"department":[{"_id":"KrCh"}],"quality_controlled":"1","_id":"1327","page":"1465 - 1466","project":[{"grant_number":"P 23499-N23","call_identifier":"FWF","name":"Modern Graph Algorithmic Techniques in Formal Verification","_id":"2584A770-B435-11E9-9278-68D0E5697425"},{"_id":"25832EC2-B435-11E9-9278-68D0E5697425","name":"Rigorous Systems Engineering","call_identifier":"FWF","grant_number":"S 11407_N23"},{"name":"International IST Postdoc Fellowship Programme","_id":"25681D80-B435-11E9-9278-68D0E5697425","grant_number":"291734","call_identifier":"FP7"},{"grant_number":"279307","call_identifier":"FP7","name":"Quantitative Graph Games: Theory and Applications","_id":"2581B60A-B435-11E9-9278-68D0E5697425"}],"date_created":"2018-12-11T11:51:23Z","status":"public","type":"conference","scopus_import":1,"title":"Stochastic shortest path with energy constraints in POMDPs","publisher":"ACM","main_file_link":[{"url":"https://arxiv.org/abs/1602.07565","open_access":"1"}],"citation":{"apa":"Brázdil, T., Chatterjee, K., Chmelik, M., Gupta, A., &#38; Novotný, P. (2016). Stochastic shortest path with energy constraints in POMDPs. In <i>Proceedings of the 15th International Conference on Autonomous Agents and Multiagent Systems</i> (pp. 1465–1466). Singapore: ACM.","mla":"Brázdil, Tomáš, et al. “Stochastic Shortest Path with Energy Constraints in POMDPs.” <i>Proceedings of the 15th International Conference on Autonomous Agents and Multiagent Systems</i>, ACM, 2016, pp. 1465–66.","chicago":"Brázdil, Tomáš, Krishnendu Chatterjee, Martin Chmelik, Anchit Gupta, and Petr Novotný. “Stochastic Shortest Path with Energy Constraints in POMDPs.” In <i>Proceedings of the 15th International Conference on Autonomous Agents and Multiagent Systems</i>, 1465–66. ACM, 2016.","ama":"Brázdil T, Chatterjee K, Chmelik M, Gupta A, Novotný P. Stochastic shortest path with energy constraints in POMDPs. In: <i>Proceedings of the 15th International Conference on Autonomous Agents and Multiagent Systems</i>. ACM; 2016:1465-1466.","short":"T. Brázdil, K. Chatterjee, M. Chmelik, A. Gupta, P. Novotný, in:, Proceedings of the 15th International Conference on Autonomous Agents and Multiagent Systems, ACM, 2016, pp. 1465–1466.","ista":"Brázdil T, Chatterjee K, Chmelik M, Gupta A, Novotný P. 2016. Stochastic shortest path with energy constraints in POMDPs. Proceedings of the 15th International Conference on Autonomous Agents and Multiagent Systems. AAMAS: Autonomous Agents &#38; Multiagent Systems, 1465–1466.","ieee":"T. Brázdil, K. Chatterjee, M. Chmelik, A. Gupta, and P. Novotný, “Stochastic shortest path with energy constraints in POMDPs,” in <i>Proceedings of the 15th International Conference on Autonomous Agents and Multiagent Systems</i>, Singapore, 2016, pp. 1465–1466."}},{"file":[{"creator":"system","date_created":"2018-12-12T10:14:04Z","checksum":"b63feece90d7b620ece49ca632e34ff3","relation":"main_file","file_id":"5053","file_name":"IST-2016-664-v1+1_acs.nanolett.6b02715.pdf","access_level":"open_access","file_size":535121,"date_updated":"2020-07-14T12:44:44Z","content_type":"application/pdf"}],"publisher":"American Chemical Society","scopus_import":1,"date_created":"2018-12-11T11:51:24Z","project":[{"call_identifier":"FP7","grant_number":"335497","name":"Towards Spin qubits and Majorana fermions in Germanium selfassembled hut-wires","_id":"25517E86-B435-11E9-9278-68D0E5697425"}],"file_date_updated":"2020-07-14T12:44:44Z","issue":"11","author":[{"last_name":"Watzinger","first_name":"Hannes","id":"35DF8E50-F248-11E8-B48F-1D18A9856A87","full_name":"Watzinger, Hannes"},{"last_name":"Kloeffel","first_name":"Christoph","full_name":"Kloeffel, Christoph"},{"full_name":"Vukusic, Lada","id":"31E9F056-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-2424-8636","last_name":"Vukusic","first_name":"Lada"},{"full_name":"Rossell, Marta","last_name":"Rossell","first_name":"Marta"},{"full_name":"Sessi, Violetta","first_name":"Violetta","last_name":"Sessi"},{"first_name":"Josip","last_name":"Kukucka","full_name":"Kukucka, Josip","id":"3F5D8856-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Kirchschlager","first_name":"Raimund","full_name":"Kirchschlager, Raimund"},{"first_name":"Elisabeth","last_name":"Lausecker","full_name":"Lausecker, Elisabeth","id":"33662F76-F248-11E8-B48F-1D18A9856A87"},{"id":"49CBC780-F248-11E8-B48F-1D18A9856A87","full_name":"Truhlar, Alisha","last_name":"Truhlar","first_name":"Alisha"},{"full_name":"Glaser, Martin","last_name":"Glaser","first_name":"Martin"},{"first_name":"Armando","last_name":"Rastelli","full_name":"Rastelli, Armando"},{"last_name":"Fuhrer","first_name":"Andreas","full_name":"Fuhrer, Andreas"},{"first_name":"Daniel","last_name":"Loss","full_name":"Loss, Daniel"},{"first_name":"Georgios","last_name":"Katsaros","orcid":"0000-0001-8342-202X","full_name":"Katsaros, Georgios","id":"38DB5788-F248-11E8-B48F-1D18A9856A87"}],"volume":16,"abstract":[{"lang":"eng","text":"Hole spins have gained considerable interest in the past few years due to their potential for fast electrically controlled qubits. Here, we study holes confined in Ge hut wires, a so-far unexplored type of nanostructure. Low-temperature magnetotransport measurements reveal a large anisotropy between the in-plane and out-of-plane g-factors of up to 18. Numerical simulations verify that this large anisotropy originates from a confined wave function of heavy-hole character. A light-hole admixture of less than 1% is estimated for the states of lowest energy, leading to a surprisingly large reduction of the out-of-plane g-factors compared with those for pure heavy holes. Given this tiny light-hole contribution, the spin lifetimes are expected to be very long, even in isotopically nonpurified samples."}],"date_published":"2016-09-22T00:00:00Z","publication":"Nano Letters","day":"22","year":"2016","language":[{"iso":"eng"}],"ec_funded":1,"citation":{"apa":"Watzinger, H., Kloeffel, C., Vukušić, L., Rossell, M., Sessi, V., Kukucka, J., … Katsaros, G. (2016). Heavy-hole states in germanium hut wires. <i>Nano Letters</i>. American Chemical Society. <a href=\"https://doi.org/10.1021/acs.nanolett.6b02715\">https://doi.org/10.1021/acs.nanolett.6b02715</a>","mla":"Watzinger, Hannes, et al. “Heavy-Hole States in Germanium Hut Wires.” <i>Nano Letters</i>, vol. 16, no. 11, American Chemical Society, 2016, pp. 6879–85, doi:<a href=\"https://doi.org/10.1021/acs.nanolett.6b02715\">10.1021/acs.nanolett.6b02715</a>.","short":"H. Watzinger, C. Kloeffel, L. Vukušić, M. Rossell, V. Sessi, J. Kukucka, R. Kirchschlager, E. Lausecker, A. Truhlar, M. Glaser, A. Rastelli, A. Fuhrer, D. Loss, G. Katsaros, Nano Letters 16 (2016) 6879–6885.","ama":"Watzinger H, Kloeffel C, Vukušić L, et al. Heavy-hole states in germanium hut wires. <i>Nano Letters</i>. 2016;16(11):6879-6885. doi:<a href=\"https://doi.org/10.1021/acs.nanolett.6b02715\">10.1021/acs.nanolett.6b02715</a>","chicago":"Watzinger, Hannes, Christoph Kloeffel, Lada Vukušić, Marta Rossell, Violetta Sessi, Josip Kukucka, Raimund Kirchschlager, et al. “Heavy-Hole States in Germanium Hut Wires.” <i>Nano Letters</i>. American Chemical Society, 2016. <a href=\"https://doi.org/10.1021/acs.nanolett.6b02715\">https://doi.org/10.1021/acs.nanolett.6b02715</a>.","ista":"Watzinger H, Kloeffel C, Vukušić L, Rossell M, Sessi V, Kukucka J, Kirchschlager R, Lausecker E, Truhlar A, Glaser M, Rastelli A, Fuhrer A, Loss D, Katsaros G. 2016. Heavy-hole states in germanium hut wires. Nano Letters. 16(11), 6879–6885.","ieee":"H. Watzinger <i>et al.</i>, “Heavy-hole states in germanium hut wires,” <i>Nano Letters</i>, vol. 16, no. 11. American Chemical Society, pp. 6879–6885, 2016."},"tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"title":"Heavy-hole states in germanium hut wires","status":"public","type":"journal_article","pubrep_id":"664","doi":"10.1021/acs.nanolett.6b02715","page":"6879 - 6885","_id":"1328","intvolume":"        16","acknowledgement":"The work was supported by the EC FP7 ICT project SiSPIN no. 323841, the EC FP7 ICT project PAMS no. 610446, the ERC Starting Grant no. 335497, the FWF-I-1190-N20 project, and the Swiss NSF. We acknowledge F. Schäffler for fruitful discussions related to the hut wire growth and for giving us access to the molecular beam epitaxy system, M. Schatzl for her support in electron beam lithography, and V. Jadris ̌ko for helping us with the COMSOL simulations. Finally, we thank G. Bauer for his continuous support. ","quality_controlled":"1","department":[{"_id":"GeKa"}],"has_accepted_license":"1","oa_version":"Published Version","month":"09","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","publist_id":"5941","related_material":{"record":[{"status":"for_moderation","id":"7977","relation":"popular_science"},{"id":"7996","relation":"dissertation_contains","status":"public"}]},"oa":1,"publication_status":"published","ddc":["539"],"date_updated":"2023-09-07T13:15:02Z"},{"date_created":"2018-12-11T11:51:24Z","scopus_import":1,"publisher":"Oxford University Press","file":[{"content_type":"application/pdf","date_updated":"2020-07-14T12:44:44Z","file_size":1406265,"access_level":"open_access","file_name":"IST-2016-663-v1+1_Genome_Biol_Evol-2016-Huylmans-3120-39.pdf","file_id":"4924","checksum":"25c7adcb452d39d3b6343ff4b57a652d","relation":"main_file","creator":"system","date_created":"2018-12-12T10:12:06Z"}],"publication":"Genome Biology and Evolution","language":[{"iso":"eng"}],"year":"2016","day":"01","author":[{"first_name":"Ann K","last_name":"Huylmans","orcid":"0000-0001-8871-4961","id":"4C0A3874-F248-11E8-B48F-1D18A9856A87","full_name":"Huylmans, Ann K"},{"first_name":"Alberto","last_name":"López Ezquerra","full_name":"López Ezquerra, Alberto"},{"full_name":"Parsch, John","first_name":"John","last_name":"Parsch"},{"first_name":"Mathilde","last_name":"Cordellier","full_name":"Cordellier, Mathilde"}],"date_published":"2016-10-01T00:00:00Z","volume":8,"abstract":[{"text":"Daphnia species have become models for ecological genomics and exhibit interesting features, such as high phenotypic plasticity and a densely packed genome with many lineage-specific genes. They are also cyclic parthenogenetic, with alternating asexual and sexual cycles and environmental sex determination. Here, we present a de novo transcriptome assembly of over 32,000 D. galeata genes and use it to investigate gene expression in females and spontaneously produced males of two clonal lines derived from lakes in Germany and the Czech Republic. We find that only a low percentage (18%) of genes shows sex-biased expression and that there are many more female-biased gene (FBG) than male-biased gene (MBG). Furthermore, FBGs tend to be more conserved between species than MBGs in both sequence and expression. These patterns may be a consequence of cyclic parthenogenesis leading to a relaxation of purifying selection on MBGs. The two clonal lines show considerable differences in both number and identity of sex-biased genes, suggesting that they may have reproductive strategies differing in their investment in sexual reproduction. Orthologs of key genes in the sex determination and juvenile hormone pathways, which are thought to be important for the transition from asexual to sexual reproduction, are present in D. galeata and highly conserved among Daphnia species.","lang":"eng"}],"file_date_updated":"2020-07-14T12:44:44Z","issue":"10","quality_controlled":"1","acknowledgement":"This study was financially supported by individual grants from the Volkswagen Stiftung (to M.C.), the Deutsche Forschungsgemeinschaft (grant PA 903/6 to J.P.) and the DAAD (to A.K.H.). The authors would like to thank I. Schrank, L. Theodosiou, M. Kredler, C. Laforsch, J. Wolinska, J. Griebel, R. Jaenichen, and K. Otte for providing the necessary resources and help for maintaining Daphnia cultures in the laboratory. H. Lainer supported us for the molecular laboratory work. D. Gilbert and J. K. Colbourne contributed ideas for the bioinformatics analysis, and L. Hardulak did the orthology mapping including more insect species. This study was financially supported by individual grants from the Volkswagen Stiftung (to M.C.), the Deutsche Forschungsgemeinschaft (grant PA 903/6 to J.P.) and the DAAD (to A.K.H.). This work benefits from and contributes to the Daphnia Genomics Consortium.","department":[{"_id":"BeVi"}],"doi":"10.1093/gbe/evw221","intvolume":"         8","_id":"1329","page":"3120 - 3139","title":"De novo transcriptome assembly and sex-biased gene expression in the cyclical parthenogenetic Daphnia galeata","tmp":{"image":"/images/cc_by_nc.png","short":"CC BY-NC (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode","name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)"},"pubrep_id":"663","status":"public","type":"journal_article","citation":{"ista":"Huylmans AK, López Ezquerra A, Parsch J, Cordellier M. 2016. De novo transcriptome assembly and sex-biased gene expression in the cyclical parthenogenetic Daphnia galeata. Genome Biology and Evolution. 8(10), 3120–3139.","ieee":"A. K. Huylmans, A. López Ezquerra, J. Parsch, and M. Cordellier, “De novo transcriptome assembly and sex-biased gene expression in the cyclical parthenogenetic Daphnia galeata,” <i>Genome Biology and Evolution</i>, vol. 8, no. 10. Oxford University Press, pp. 3120–3139, 2016.","short":"A.K. Huylmans, A. López Ezquerra, J. Parsch, M. Cordellier, Genome Biology and Evolution 8 (2016) 3120–3139.","chicago":"Huylmans, Ann K, Alberto López Ezquerra, John Parsch, and Mathilde Cordellier. “De Novo Transcriptome Assembly and Sex-Biased Gene Expression in the Cyclical Parthenogenetic Daphnia Galeata.” <i>Genome Biology and Evolution</i>. Oxford University Press, 2016. <a href=\"https://doi.org/10.1093/gbe/evw221\">https://doi.org/10.1093/gbe/evw221</a>.","ama":"Huylmans AK, López Ezquerra A, Parsch J, Cordellier M. De novo transcriptome assembly and sex-biased gene expression in the cyclical parthenogenetic Daphnia galeata. <i>Genome Biology and Evolution</i>. 2016;8(10):3120-3139. doi:<a href=\"https://doi.org/10.1093/gbe/evw221\">10.1093/gbe/evw221</a>","mla":"Huylmans, Ann K., et al. “De Novo Transcriptome Assembly and Sex-Biased Gene Expression in the Cyclical Parthenogenetic Daphnia Galeata.” <i>Genome Biology and Evolution</i>, vol. 8, no. 10, Oxford University Press, 2016, pp. 3120–39, doi:<a href=\"https://doi.org/10.1093/gbe/evw221\">10.1093/gbe/evw221</a>.","apa":"Huylmans, A. K., López Ezquerra, A., Parsch, J., &#38; Cordellier, M. (2016). De novo transcriptome assembly and sex-biased gene expression in the cyclical parthenogenetic Daphnia galeata. <i>Genome Biology and Evolution</i>. Oxford University Press. <a href=\"https://doi.org/10.1093/gbe/evw221\">https://doi.org/10.1093/gbe/evw221</a>"},"oa":1,"publication_status":"published","ddc":["576"],"date_updated":"2021-01-12T06:49:55Z","oa_version":"Published Version","month":"10","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","publist_id":"5940","has_accepted_license":"1"},{"year":"2016","language":[{"iso":"eng"}],"day":"15","publication":"Israel Journal of Mathematics","ec_funded":1,"issue":"2","date_published":"2016-10-15T00:00:00Z","abstract":[{"text":"In this paper we investigate the existence of closed billiard trajectories in not necessarily smooth convex bodies. In particular, we show that if a body K ⊂ Rd has the property that the tangent cone of every non-smooth point q ∉ ∂K is acute (in a certain sense), then there is a closed billiard trajectory in K.","lang":"eng"}],"volume":216,"author":[{"id":"430D2C90-F248-11E8-B48F-1D18A9856A87","full_name":"Akopyan, Arseniy","last_name":"Akopyan","first_name":"Arseniy","orcid":"0000-0002-2548-617X"},{"full_name":"Balitskiy, Alexey","first_name":"Alexey","last_name":"Balitskiy"}],"date_created":"2018-12-11T11:51:24Z","project":[{"_id":"25681D80-B435-11E9-9278-68D0E5697425","name":"International IST Postdoc Fellowship Programme","grant_number":"291734","call_identifier":"FP7"}],"main_file_link":[{"url":"https://arxiv.org/abs/1506.06014","open_access":"1"}],"publisher":"Springer","scopus_import":1,"user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","publist_id":"5938","month":"10","oa_version":"Preprint","date_updated":"2021-01-12T06:49:56Z","publication_status":"published","oa":1,"intvolume":"       216","page":"833 - 845","_id":"1330","doi":"10.1007/s11856-016-1429-z","department":[{"_id":"HeEd"}],"quality_controlled":"1","acknowledgement":"Supported by People Programme (Marie Curie Actions) of the European Union’s Seventh Framework Programme (FP7/2007-2013) under REA grant agreement n°[291734]. Supported by the Russian Foundation for Basic Research grant 15-31-20403 (mol a ved), by the Russian Foundation for Basic Research grant 15-01-99563 A, in part by the Moebius Contest Foundation for Young Scientists, and in part by the Simons Foundation.","citation":{"apa":"Akopyan, A., &#38; Balitskiy, A. (2016). Billiards in convex bodies with acute angles. <i>Israel Journal of Mathematics</i>. Springer. <a href=\"https://doi.org/10.1007/s11856-016-1429-z\">https://doi.org/10.1007/s11856-016-1429-z</a>","mla":"Akopyan, Arseniy, and Alexey Balitskiy. “Billiards in Convex Bodies with Acute Angles.” <i>Israel Journal of Mathematics</i>, vol. 216, no. 2, Springer, 2016, pp. 833–45, doi:<a href=\"https://doi.org/10.1007/s11856-016-1429-z\">10.1007/s11856-016-1429-z</a>.","chicago":"Akopyan, Arseniy, and Alexey Balitskiy. “Billiards in Convex Bodies with Acute Angles.” <i>Israel Journal of Mathematics</i>. Springer, 2016. <a href=\"https://doi.org/10.1007/s11856-016-1429-z\">https://doi.org/10.1007/s11856-016-1429-z</a>.","ama":"Akopyan A, Balitskiy A. Billiards in convex bodies with acute angles. <i>Israel Journal of Mathematics</i>. 2016;216(2):833-845. doi:<a href=\"https://doi.org/10.1007/s11856-016-1429-z\">10.1007/s11856-016-1429-z</a>","short":"A. Akopyan, A. Balitskiy, Israel Journal of Mathematics 216 (2016) 833–845.","ista":"Akopyan A, Balitskiy A. 2016. Billiards in convex bodies with acute angles. Israel Journal of Mathematics. 216(2), 833–845.","ieee":"A. Akopyan and A. Balitskiy, “Billiards in convex bodies with acute angles,” <i>Israel Journal of Mathematics</i>, vol. 216, no. 2. Springer, pp. 833–845, 2016."},"status":"public","type":"journal_article","title":"Billiards in convex bodies with acute angles"},{"publist_id":"5937","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa_version":"Published Version","month":"10","publication_identifier":{"eissn":["1532-2548"],"issn":["0032-0889"]},"date_updated":"2022-05-24T09:26:03Z","publication_status":"published","oa":1,"citation":{"apa":"Zwack, P., De Clercq, I., Howton, T., Hallmark, H. T., Hurny, A., Keshishian, E., … Rashotte, A. (2016). Cytokinin response factor 6 represses cytokinin-associated genes during oxidative stress. <i>Plant Physiology</i>. American Society of Plant Biologists. <a href=\"https://doi.org/10.1104/pp.16.00415\">https://doi.org/10.1104/pp.16.00415</a>","mla":"Zwack, Paul, et al. “Cytokinin Response Factor 6 Represses Cytokinin-Associated Genes during Oxidative Stress.” <i>Plant Physiology</i>, vol. 172, no. 2, American Society of Plant Biologists, 2016, pp. 1249–58, doi:<a href=\"https://doi.org/10.1104/pp.16.00415\">10.1104/pp.16.00415</a>.","short":"P. Zwack, I. De Clercq, T. Howton, H.T. Hallmark, A. Hurny, E. Keshishian, A. Parish, E. Benková, M.S. Mukhtar, F. Van Breusegem, A. Rashotte, Plant Physiology 172 (2016) 1249–1258.","chicago":"Zwack, Paul, Inge De Clercq, Timothy Howton, H Tucker Hallmark, Andrej Hurny, Erika Keshishian, Alyssa Parish, et al. “Cytokinin Response Factor 6 Represses Cytokinin-Associated Genes during Oxidative Stress.” <i>Plant Physiology</i>. American Society of Plant Biologists, 2016. <a href=\"https://doi.org/10.1104/pp.16.00415\">https://doi.org/10.1104/pp.16.00415</a>.","ama":"Zwack P, De Clercq I, Howton T, et al. Cytokinin response factor 6 represses cytokinin-associated genes during oxidative stress. <i>Plant Physiology</i>. 2016;172(2):1249-1258. doi:<a href=\"https://doi.org/10.1104/pp.16.00415\">10.1104/pp.16.00415</a>","ieee":"P. Zwack <i>et al.</i>, “Cytokinin response factor 6 represses cytokinin-associated genes during oxidative stress,” <i>Plant Physiology</i>, vol. 172, no. 2. American Society of Plant Biologists, pp. 1249–1258, 2016.","ista":"Zwack P, De Clercq I, Howton T, Hallmark HT, Hurny A, Keshishian E, Parish A, Benková E, Mukhtar MS, Van Breusegem F, Rashotte A. 2016. Cytokinin response factor 6 represses cytokinin-associated genes during oxidative stress. Plant Physiology. 172(2), 1249–1258."},"article_processing_charge":"No","type":"journal_article","status":"public","title":"Cytokinin response factor 6 represses cytokinin-associated genes during oxidative stress","intvolume":"       172","page":"1249 - 1258","_id":"1331","doi":"10.1104/pp.16.00415","department":[{"_id":"EvBe"}],"quality_controlled":"1","acknowledgement":"This work was financially supported by the following: The Alabama Agricultural Experiment Station HATCH grants 370222-310010-2055 and 370225-310006-2055 for funding to P.J.Z., E.A.K, A.M.P., and A.M.R. P.J.Z. and E.A.K were supported by an Auburn University Cellular and Molecular Biosciences Research Fellowship. I.D.C. is a postdoctoral fellow of the Research Foundation Flanders (FWO) (FWO/PDO14/043) and is also supported by FWO travel\r\ngrant 12N2415N. F.V.B. was supported by grants from the Interuniversity Attraction Poles Programme (IUAP P7/29 MARS) initiated by the Belgian Science Policy Office and Ghent University (Multidisciplinary Research Partnership Biotechnology for a Sustainable Economy, grant 01MRB510W).","issue":"2","date_published":"2016-10-02T00:00:00Z","abstract":[{"lang":"eng","text":"Cytokinin is a phytohormone that is well known for its roles in numerous plant growth and developmental processes, yet it has also been linked to abiotic stress response in a less defined manner. Arabidopsis (Arabidopsis thaliana) Cytokinin Response Factor 6 (CRF6) is a cytokinin-responsive AP2/ERF-family transcription factor that, through the cytokinin signaling pathway, plays a key role in the inhibition of dark-induced senescence. CRF6 expression is also induced by oxidative stress, and here we show a novel function for CRF6 in relation to oxidative stress and identify downstream transcriptional targets of CRF6 that are repressed in response to oxidative stress. Analysis of transcriptomic changes in wild-type and crf6 mutant plants treated with H2O2 identified CRF6-dependent differentially expressed transcripts, many of which were repressed rather than induced. Moreover, many repressed genes also show decreased expression in 35S:CRF6 overexpressing plants. Together, these findings suggest that CRF6 functions largely as a transcriptional repressor. Interestingly, among the H2O2 repressed CRF6-dependent transcripts was a set of five genes associated with cytokinin processes: (signaling) ARR6, ARR9, ARR11, (biosynthesis) LOG7, and (transport) ABCG14. We have examined mutants of these cytokinin-associated target genes to reveal novel connections to oxidative stress. Further examination of CRF6-DNA interactions indicated that CRF6 may regulate its targets both directly and indirectly. Together, this shows that CRF6 functions during oxidative stress as a negative regulator to control this cytokinin-associated module of CRF6- dependent genes and establishes a novel connection between cytokinin and oxidative stress response."}],"volume":172,"author":[{"last_name":"Zwack","first_name":"Paul","full_name":"Zwack, Paul"},{"last_name":"De Clercq","first_name":"Inge","full_name":"De Clercq, Inge"},{"first_name":"Timothy","last_name":"Howton","full_name":"Howton, Timothy"},{"full_name":"Hallmark, H Tucker","first_name":"H Tucker","last_name":"Hallmark"},{"last_name":"Hurny","first_name":"Andrej","full_name":"Hurny, Andrej","id":"4DC4AF46-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Erika","last_name":"Keshishian","full_name":"Keshishian, Erika"},{"full_name":"Parish, Alyssa","first_name":"Alyssa","last_name":"Parish"},{"id":"38F4F166-F248-11E8-B48F-1D18A9856A87","full_name":"Benková, Eva","orcid":"0000-0002-8510-9739","first_name":"Eva","last_name":"Benková"},{"last_name":"Mukhtar","first_name":"M Shahid","full_name":"Mukhtar, M Shahid"},{"full_name":"Van Breusegem, Frank","first_name":"Frank","last_name":"Van Breusegem"},{"full_name":"Rashotte, Aaron","first_name":"Aaron","last_name":"Rashotte"}],"language":[{"iso":"eng"}],"year":"2016","day":"02","publication":"Plant Physiology","main_file_link":[{"url":"https://doi.org/10.1104/pp.16.00415","open_access":"1"}],"publisher":"American Society of Plant Biologists","scopus_import":"1","date_created":"2018-12-11T11:51:25Z","article_type":"original"},{"article_number":"10333","has_accepted_license":"1","oa":1,"publication_status":"published","date_updated":"2021-01-12T06:49:57Z","ddc":["570","579"],"oa_version":"Published Version","month":"01","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","publist_id":"5936","title":"Pervasive selection for and against antibiotic resistance in inhomogeneous multistress environments","tmp":{"short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"pubrep_id":"662","status":"public","type":"journal_article","citation":{"short":"R.P. Chait, A. Palmer, I. Yelin, R. Kishony, Nature Communications 7 (2016).","chicago":"Chait, Remy P, Adam Palmer, Idan Yelin, and Roy Kishony. “Pervasive Selection for and against Antibiotic Resistance in Inhomogeneous Multistress Environments.” <i>Nature Communications</i>. Nature Publishing Group, 2016. <a href=\"https://doi.org/10.1038/ncomms10333\">https://doi.org/10.1038/ncomms10333</a>.","ama":"Chait RP, Palmer A, Yelin I, Kishony R. Pervasive selection for and against antibiotic resistance in inhomogeneous multistress environments. <i>Nature Communications</i>. 2016;7. doi:<a href=\"https://doi.org/10.1038/ncomms10333\">10.1038/ncomms10333</a>","apa":"Chait, R. P., Palmer, A., Yelin, I., &#38; Kishony, R. (2016). Pervasive selection for and against antibiotic resistance in inhomogeneous multistress environments. <i>Nature Communications</i>. Nature Publishing Group. <a href=\"https://doi.org/10.1038/ncomms10333\">https://doi.org/10.1038/ncomms10333</a>","mla":"Chait, Remy P., et al. “Pervasive Selection for and against Antibiotic Resistance in Inhomogeneous Multistress Environments.” <i>Nature Communications</i>, vol. 7, 10333, Nature Publishing Group, 2016, doi:<a href=\"https://doi.org/10.1038/ncomms10333\">10.1038/ncomms10333</a>.","ista":"Chait RP, Palmer A, Yelin I, Kishony R. 2016. Pervasive selection for and against antibiotic resistance in inhomogeneous multistress environments. Nature Communications. 7, 10333.","ieee":"R. P. Chait, A. Palmer, I. Yelin, and R. Kishony, “Pervasive selection for and against antibiotic resistance in inhomogeneous multistress environments,” <i>Nature Communications</i>, vol. 7. Nature Publishing Group, 2016."},"quality_controlled":"1","acknowledgement":"This work was partially supported by US National Institutes of Health grant R01-GM081617, Israeli Centers of Research Excellence I-CORE Program ISF Grant No. 152/11, and the European Research Council FP7 ERC Grant 281891.","department":[{"_id":"CaGu"},{"_id":"GaTk"}],"doi":"10.1038/ncomms10333","intvolume":"         7","_id":"1332","author":[{"orcid":"0000-0003-0876-3187","last_name":"Chait","first_name":"Remy P","full_name":"Chait, Remy P","id":"3464AE84-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Palmer","first_name":"Adam","full_name":"Palmer, Adam"},{"full_name":"Yelin, Idan","last_name":"Yelin","first_name":"Idan"},{"full_name":"Kishony, Roy","first_name":"Roy","last_name":"Kishony"}],"date_published":"2016-01-20T00:00:00Z","abstract":[{"text":"Antibiotic-sensitive and -resistant bacteria coexist in natural environments with low, if detectable, antibiotic concentrations. Except possibly around localized antibiotic sources, where resistance can provide a strong advantage, bacterial fitness is dominated by stresses unaffected by resistance to the antibiotic. How do such mixed and heterogeneous conditions influence the selective advantage or disadvantage of antibiotic resistance? Here we find that sub-inhibitory levels of tetracyclines potentiate selection for or against tetracycline resistance around localized sources of almost any toxin or stress. Furthermore, certain stresses generate alternating rings of selection for and against resistance around a localized source of the antibiotic. In these conditions, localized antibiotic sources, even at high strengths, can actually produce a net selection against resistance to the antibiotic. Our results show that interactions between the effects of an antibiotic and other stresses in inhomogeneous environments can generate pervasive, complex patterns of selection both for and against antibiotic resistance.","lang":"eng"}],"volume":7,"file_date_updated":"2020-07-14T12:44:44Z","publication":"Nature Communications","language":[{"iso":"eng"}],"year":"2016","day":"20","scopus_import":1,"publisher":"Nature Publishing Group","file":[{"date_updated":"2020-07-14T12:44:44Z","content_type":"application/pdf","file_name":"IST-2016-662-v1+1_ncomms10333.pdf","file_size":1844107,"access_level":"open_access","file_id":"5039","date_created":"2018-12-12T10:13:52Z","creator":"system","relation":"main_file","checksum":"ef147bcbb8bd37e9079cf3ce06f5815d"}],"date_created":"2018-12-11T11:51:25Z"}]