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Uniqueness and nondegeneracy of minimizers of the Pekar functional on a ball. SIAM Journal on Mathematical Analysis. 52(1), 605–622.","chicago":"Feliciangeli, Dario, and Robert Seiringer. “Uniqueness and Nondegeneracy of Minimizers of the Pekar Functional on a Ball.” <i>SIAM Journal on Mathematical Analysis</i>. Society for Industrial &#38; Applied Mathematics , 2020. <a href=\"https://doi.org/10.1137/19m126284x\">https://doi.org/10.1137/19m126284x</a>.","short":"D. Feliciangeli, R. Seiringer, SIAM Journal on Mathematical Analysis 52 (2020) 605–622.","ieee":"D. Feliciangeli and R. Seiringer, “Uniqueness and nondegeneracy of minimizers of the Pekar functional on a ball,” <i>SIAM Journal on Mathematical Analysis</i>, vol. 52, no. 1. Society for Industrial &#38; Applied Mathematics , pp. 605–622, 2020.","ama":"Feliciangeli D, Seiringer R. 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Society for Industrial &#38; Applied Mathematics . <a href=\"https://doi.org/10.1137/19m126284x\">https://doi.org/10.1137/19m126284x</a>"},"author":[{"id":"41A639AA-F248-11E8-B48F-1D18A9856A87","full_name":"Feliciangeli, Dario","orcid":"0000-0003-0754-8530","last_name":"Feliciangeli","first_name":"Dario"},{"full_name":"Seiringer, Robert","orcid":"0000-0002-6781-0521","id":"4AFD0470-F248-11E8-B48F-1D18A9856A87","first_name":"Robert","last_name":"Seiringer"}],"quality_controlled":"1","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","short":"CC BY-NC-ND (4.0)","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","image":"/images/cc_by_nc_nd.png"},"year":"2020","title":"Uniqueness and nondegeneracy of minimizers of the Pekar functional on a ball","publication":"SIAM Journal on Mathematical Analysis","ddc":["510"],"oa":1,"related_material":{"record":[{"id":"9733","status":"public","relation":"dissertation_contains"}]},"_id":"9781","project":[{"grant_number":"694227","name":"Analysis of quantum many-body systems","call_identifier":"H2020","_id":"25C6DC12-B435-11E9-9278-68D0E5697425"}],"publication_status":"published","abstract":[{"lang":"eng","text":"We consider the Pekar functional on a ball in ℝ3. We prove uniqueness of minimizers, and a quadratic lower bound in terms of the distance to the minimizer. The latter follows from nondegeneracy of the Hessian at the minimum."}],"date_published":"2020-02-12T00:00:00Z","keyword":["Applied Mathematics","Computational Mathematics","Analysis"],"external_id":{"arxiv":["1904.08647 "],"isi":["000546967700022"]},"page":"605-622","publication_identifier":{"issn":["0036-1410"],"eissn":["1095-7154"]},"scopus_import":"1","arxiv":1,"user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","article_processing_charge":"No","type":"journal_article","date_updated":"2023-09-07T13:30:11Z","oa_version":"Preprint","day":"12","ec_funded":1,"language":[{"iso":"eng"}],"doi":"10.1137/19m126284x","department":[{"_id":"RoSe"}],"has_accepted_license":"1","acknowledgement":"We are grateful for the hospitality at the Mittag-Leffler Institute, where part of this work has been done. The work of the authors was supported by the European Research Council (ERC)under the European Union's Horizon 2020 research and innovation programme grant 694227."},{"date_created":"2021-08-06T11:18:15Z","month":"10","status":"public","date_published":"2020-10-15T00:00:00Z","publisher":"Royal Society of London","title":"Simulation code for Fig S2 from the distribution of epistasis on simple fitness landscapes","doi":"10.6084/m9.figshare.7957472.v1","related_material":{"record":[{"status":"public","relation":"used_in_publication","id":"6467"}]},"oa":1,"_id":"9798","department":[{"_id":"BeVi"},{"_id":"NiBa"}],"abstract":[{"text":"Fitness interactions between mutations can influence a population’s evolution in many different ways. While epistatic effects are difficult to measure precisely, important information is captured by the mean and variance of log fitnesses for individuals carrying different numbers of mutations. We derive predictions for these quantities from a class of simple fitness landscapes, based on models of optimizing selection on quantitative traits. We also explore extensions to the models, including modular pleiotropy, variable effect sizes, mutational bias and maladaptation of the wild type. We illustrate our approach by reanalysing a large dataset of mutant effects in a yeast snoRNA. Though characterized by some large epistatic effects, these data give a good overall fit to the non-epistatic null model, suggesting that epistasis might have limited influence on the evolutionary dynamics in this system. We also show how the amount of epistasis depends on both the underlying fitness landscape and the distribution of mutations, and so is expected to vary in consistent ways between new mutations, standing variation and fixed mutations.","lang":"eng"}],"main_file_link":[{"open_access":"1","url":"https://doi.org/10.6084/m9.figshare.7957472.v1"}],"citation":{"apa":"Fraisse, C., &#38; Welch, J. J. (2020). Simulation code for Fig S2 from the distribution of epistasis on simple fitness landscapes. Royal Society of London. <a href=\"https://doi.org/10.6084/m9.figshare.7957472.v1\">https://doi.org/10.6084/m9.figshare.7957472.v1</a>","mla":"Fraisse, Christelle, and John J. Welch. <i>Simulation Code for Fig S2 from the Distribution of Epistasis on Simple Fitness Landscapes</i>. Royal Society of London, 2020, doi:<a href=\"https://doi.org/10.6084/m9.figshare.7957472.v1\">10.6084/m9.figshare.7957472.v1</a>.","ieee":"C. Fraisse and J. J. 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We also show how the amount of epistasis depends on both the underlying fitness landscape and the distribution of mutations, and so is expected to vary in consistent ways between new mutations, standing variation and fixed mutations."}],"title":"Simulation code for Fig S1 from the distribution of epistasis on simple fitness landscapes","doi":"10.6084/m9.figshare.7957469.v1","oa":1,"related_material":{"record":[{"status":"public","relation":"used_in_publication","id":"6467"}]},"_id":"9799","department":[{"_id":"BeVi"},{"_id":"NiBa"}],"type":"research_data_reference","date_updated":"2023-08-25T10:34:41Z","oa_version":"Published Version","day":"15","year":"2020","citation":{"chicago":"Fraisse, Christelle, and John J. Welch. “Simulation Code for Fig S1 from the Distribution of Epistasis on Simple Fitness Landscapes.” Royal Society of London, 2020. <a href=\"https://doi.org/10.6084/m9.figshare.7957469.v1\">https://doi.org/10.6084/m9.figshare.7957469.v1</a>.","short":"C. Fraisse, J.J. 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Nowak, “Data and mathematica notebooks for plotting figures from language learning with communication between learners from language acquisition with communication between learners.” Royal Society, 2020.","short":"R. Ibsen-Jensen, J. Tkadlec, K. Chatterjee, M. Nowak, (2020).","chicago":"Ibsen-Jensen, Rasmus, Josef Tkadlec, Krishnendu Chatterjee, and Martin Nowak. “Data and Mathematica Notebooks for Plotting Figures from Language Learning with Communication between Learners from Language Acquisition with Communication between Learners.” Royal Society, 2020. <a href=\"https://doi.org/10.6084/m9.figshare.5973013.v1\">https://doi.org/10.6084/m9.figshare.5973013.v1</a>.","ista":"Ibsen-Jensen R, Tkadlec J, Chatterjee K, Nowak M. 2020. Data and mathematica notebooks for plotting figures from language learning with communication between learners from language acquisition with communication between learners, Royal Society, <a href=\"https://doi.org/10.6084/m9.figshare.5973013.v1\">10.6084/m9.figshare.5973013.v1</a>."},"abstract":[{"lang":"eng","text":"Data and mathematica notebooks for plotting figures from Language learning with communication between learners"}],"department":[{"_id":"KrCh"}],"_id":"9814","oa":1,"related_material":{"record":[{"id":"198","relation":"used_in_publication","status":"public"}]},"doi":"10.6084/m9.figshare.5973013.v1","title":"Data and mathematica notebooks for plotting figures from language learning with communication between learners from language acquisition with communication between learners","publisher":"Royal Society","date_published":"2020-10-15T00:00:00Z","status":"public","month":"10","date_created":"2021-08-06T13:09:57Z"},{"date_created":"2021-08-11T09:18:54Z","month":"05","status":"public","date_published":"2020-05-20T00:00:00Z","publisher":"American Chemical Society","title":"Movies","doi":"10.1021/jacs.9b13450.s002","related_material":{"record":[{"id":"8040","status":"public","relation":"used_in_publication"}]},"_id":"9878","department":[{"_id":"LeSa"}],"citation":{"apa":"Gupta, C., Khaniya, U., Chan, C. K., Dehez, F., Shekhar, M., Gunner, M. R., … Singharoy, A. (2020). Movies. American Chemical Society. <a href=\"https://doi.org/10.1021/jacs.9b13450.s002\">https://doi.org/10.1021/jacs.9b13450.s002</a>","mla":"Gupta, Chitrak, et al. <i>Movies</i>. American Chemical Society, 2020, doi:<a href=\"https://doi.org/10.1021/jacs.9b13450.s002\">10.1021/jacs.9b13450.s002</a>.","chicago":"Gupta, Chitrak, Umesh Khaniya, Chun Kit Chan, Francois Dehez, Mrinal Shekhar, M.R. Gunner, Leonid A Sazanov, Christophe Chipot, and Abhishek Singharoy. “Movies.” American Chemical Society, 2020. <a href=\"https://doi.org/10.1021/jacs.9b13450.s002\">https://doi.org/10.1021/jacs.9b13450.s002</a>.","short":"C. Gupta, U. Khaniya, C.K. Chan, F. Dehez, M. Shekhar, M.R. Gunner, L.A. Sazanov, C. Chipot, A. Singharoy, (2020).","ista":"Gupta C, Khaniya U, Chan CK, Dehez F, Shekhar M, Gunner MR, Sazanov LA, Chipot C, Singharoy A. 2020. Movies, American Chemical Society, <a href=\"https://doi.org/10.1021/jacs.9b13450.s002\">10.1021/jacs.9b13450.s002</a>.","ieee":"C. Gupta <i>et al.</i>, “Movies.” American Chemical Society, 2020.","ama":"Gupta C, Khaniya U, Chan CK, et al. Movies. 2020. doi:<a href=\"https://doi.org/10.1021/jacs.9b13450.s002\">10.1021/jacs.9b13450.s002</a>"},"article_processing_charge":"No","user_id":"6785fbc1-c503-11eb-8a32-93094b40e1cf","author":[{"last_name":"Gupta","first_name":"Chitrak","full_name":"Gupta, Chitrak"},{"full_name":"Khaniya, Umesh","first_name":"Umesh","last_name":"Khaniya"},{"last_name":"Chan","first_name":"Chun Kit","full_name":"Chan, Chun Kit"},{"last_name":"Dehez","first_name":"Francois","full_name":"Dehez, Francois"},{"full_name":"Shekhar, Mrinal","last_name":"Shekhar","first_name":"Mrinal"},{"full_name":"Gunner, M.R.","last_name":"Gunner","first_name":"M.R."},{"first_name":"Leonid A","last_name":"Sazanov","id":"338D39FE-F248-11E8-B48F-1D18A9856A87","full_name":"Sazanov, Leonid A","orcid":"0000-0002-0977-7989"},{"first_name":"Christophe","last_name":"Chipot","full_name":"Chipot, Christophe"},{"full_name":"Singharoy, Abhishek","last_name":"Singharoy","first_name":"Abhishek"}],"type":"research_data_reference","date_updated":"2023-08-22T07:49:38Z","oa_version":"Published Version","day":"20","year":"2020"},{"date_published":"2020-01-08T00:00:00Z","publisher":"American Chemical Society ","date_created":"2021-08-11T13:16:03Z","month":"01","status":"public","citation":{"apa":"Ucar, M. C., &#38; Lipowsky, R. (2020). MURL_Dataz. American Chemical Society . <a href=\"https://doi.org/10.1021/acs.nanolett.9b04445.s002\">https://doi.org/10.1021/acs.nanolett.9b04445.s002</a>","mla":"Ucar, Mehmet C., and Reinhard Lipowsky. <i>MURL_Dataz</i>. American Chemical Society , 2020, doi:<a href=\"https://doi.org/10.1021/acs.nanolett.9b04445.s002\">10.1021/acs.nanolett.9b04445.s002</a>.","short":"M.C. Ucar, R. Lipowsky, (2020).","chicago":"Ucar, Mehmet C, and Reinhard Lipowsky. “MURL_Dataz.” American Chemical Society , 2020. <a href=\"https://doi.org/10.1021/acs.nanolett.9b04445.s002\">https://doi.org/10.1021/acs.nanolett.9b04445.s002</a>.","ista":"Ucar MC, Lipowsky R. 2020. MURL_Dataz, American Chemical Society , <a href=\"https://doi.org/10.1021/acs.nanolett.9b04445.s002\">10.1021/acs.nanolett.9b04445.s002</a>.","ieee":"M. C. Ucar and R. Lipowsky, “MURL_Dataz.” American Chemical Society , 2020.","ama":"Ucar MC, Lipowsky R. MURL_Dataz. 2020. doi:<a href=\"https://doi.org/10.1021/acs.nanolett.9b04445.s002\">10.1021/acs.nanolett.9b04445.s002</a>"},"author":[{"id":"50B2A802-6007-11E9-A42B-EB23E6697425","orcid":"0000-0003-0506-4217","full_name":"Ucar, Mehmet C","first_name":"Mehmet C","last_name":"Ucar"},{"full_name":"Lipowsky, Reinhard","first_name":"Reinhard","last_name":"Lipowsky"}],"user_id":"6785fbc1-c503-11eb-8a32-93094b40e1cf","article_processing_charge":"No","date_updated":"2023-08-17T14:07:52Z","type":"research_data_reference","oa_version":"Published Version","day":"08","year":"2020","title":"MURL_Dataz","related_material":{"record":[{"id":"7166","status":"public","relation":"used_in_publication"}]},"doi":"10.1021/acs.nanolett.9b04445.s002","department":[{"_id":"EdHa"}],"_id":"9885","abstract":[{"text":"Data obtained from the fine-grained simulations used in Figures 2-5, data obtained from the coarse-grained numerical calculations used in Figure 6, and a sample script for the fine-grained simulation as a Jupyter notebook (ZIP)","lang":"eng"}]},{"language":[{"iso":"eng"}],"doi":"10.1007/s10009-020-00582-z","department":[{"_id":"ToHe"}],"type":"journal_article","date_updated":"2023-09-08T11:52:02Z","oa_version":"None","day":"03","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","article_processing_charge":"No","publication_identifier":{"eissn":["1433-2787"],"issn":["1433-2779"]},"scopus_import":"1","date_published":"2020-08-03T00:00:00Z","keyword":["Information Systems","Software"],"external_id":{"isi":["000555398600001"]},"page":"741-758","publication_status":"published","abstract":[{"text":"We introduce in this paper AMT2.0, a tool for qualitative and quantitative analysis of hybrid continuous and Boolean signals that combine numerical values and discrete events. The evaluation of the signals is based on rich temporal specifications expressed in extended signal temporal logic, which integrates timed regular expressions within signal temporal logic. The tool features qualitative monitoring (property satisfaction checking), trace diagnostics for explaining and justifying property violations and specification-driven measurement of quantitative features of the signal. We demonstrate the tool functionality on several running examples and case studies, and evaluate its performance.","lang":"eng"}],"publication":"International Journal on Software Tools for Technology Transfer","title":"AMT 2.0: Qualitative and quantitative trace analysis with extended signal temporal logic","related_material":{"record":[{"relation":"earlier_version","status":"public","id":"299"}]},"_id":"10861","year":"2020","citation":{"mla":"Nickovic, Dejan, et al. “AMT 2.0: Qualitative and Quantitative Trace Analysis with Extended Signal Temporal Logic.” <i>International Journal on Software Tools for Technology Transfer</i>, vol. 22, no. 6, Springer Nature, 2020, pp. 741–58, doi:<a href=\"https://doi.org/10.1007/s10009-020-00582-z\">10.1007/s10009-020-00582-z</a>.","apa":"Nickovic, D., Lebeltel, O., Maler, O., Ferrere, T., &#38; Ulus, D. (2020). AMT 2.0: Qualitative and quantitative trace analysis with extended signal temporal logic. <i>International Journal on Software Tools for Technology Transfer</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s10009-020-00582-z\">https://doi.org/10.1007/s10009-020-00582-z</a>","ieee":"D. Nickovic, O. Lebeltel, O. Maler, T. Ferrere, and D. Ulus, “AMT 2.0: Qualitative and quantitative trace analysis with extended signal temporal logic,” <i>International Journal on Software Tools for Technology Transfer</i>, vol. 22, no. 6. Springer Nature, pp. 741–758, 2020.","ama":"Nickovic D, Lebeltel O, Maler O, Ferrere T, Ulus D. AMT 2.0: Qualitative and quantitative trace analysis with extended signal temporal logic. <i>International Journal on Software Tools for Technology Transfer</i>. 2020;22(6):741-758. doi:<a href=\"https://doi.org/10.1007/s10009-020-00582-z\">10.1007/s10009-020-00582-z</a>","ista":"Nickovic D, Lebeltel O, Maler O, Ferrere T, Ulus D. 2020. AMT 2.0: Qualitative and quantitative trace analysis with extended signal temporal logic. International Journal on Software Tools for Technology Transfer. 22(6), 741–758.","short":"D. Nickovic, O. Lebeltel, O. Maler, T. Ferrere, D. Ulus, International Journal on Software Tools for Technology Transfer 22 (2020) 741–758.","chicago":"Nickovic, Dejan, Olivier Lebeltel, Oded Maler, Thomas Ferrere, and Dogan Ulus. “AMT 2.0: Qualitative and Quantitative Trace Analysis with Extended Signal Temporal Logic.” <i>International Journal on Software Tools for Technology Transfer</i>. Springer Nature, 2020. <a href=\"https://doi.org/10.1007/s10009-020-00582-z\">https://doi.org/10.1007/s10009-020-00582-z</a>."},"quality_controlled":"1","author":[{"first_name":"Dejan","last_name":"Nickovic","full_name":"Nickovic, Dejan","id":"41BCEE5C-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Lebeltel","first_name":"Olivier","full_name":"Lebeltel, Olivier"},{"full_name":"Maler, Oded","last_name":"Maler","first_name":"Oded"},{"first_name":"Thomas","last_name":"Ferrere","full_name":"Ferrere, Thomas","orcid":"0000-0001-5199-3143","id":"40960E6E-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Ulus, Dogan","last_name":"Ulus","first_name":"Dogan"}],"date_created":"2022-03-18T10:10:53Z","month":"08","status":"public","intvolume":"        22","isi":1,"publisher":"Springer Nature","article_type":"original","issue":"6","volume":22},{"article_type":"original","publisher":"Elsevier","issue":"7","volume":279,"month":"10","date_created":"2022-03-18T10:18:59Z","article_number":"108639","status":"public","intvolume":"       279","isi":1,"year":"2020","citation":{"ama":"Bao Z, Erdös L, Schnelli K. Spectral rigidity for addition of random matrices at the regular edge. <i>Journal of Functional Analysis</i>. 2020;279(7). doi:<a href=\"https://doi.org/10.1016/j.jfa.2020.108639\">10.1016/j.jfa.2020.108639</a>","ieee":"Z. Bao, L. Erdös, and K. Schnelli, “Spectral rigidity for addition of random matrices at the regular edge,” <i>Journal of Functional Analysis</i>, vol. 279, no. 7. Elsevier, 2020.","ista":"Bao Z, Erdös L, Schnelli K. 2020. Spectral rigidity for addition of random matrices at the regular edge. Journal of Functional Analysis. 279(7), 108639.","chicago":"Bao, Zhigang, László Erdös, and Kevin Schnelli. “Spectral Rigidity for Addition of Random Matrices at the Regular Edge.” <i>Journal of Functional Analysis</i>. Elsevier, 2020. <a href=\"https://doi.org/10.1016/j.jfa.2020.108639\">https://doi.org/10.1016/j.jfa.2020.108639</a>.","short":"Z. Bao, L. Erdös, K. Schnelli, Journal of Functional Analysis 279 (2020).","mla":"Bao, Zhigang, et al. “Spectral Rigidity for Addition of Random Matrices at the Regular Edge.” <i>Journal of Functional Analysis</i>, vol. 279, no. 7, 108639, Elsevier, 2020, doi:<a href=\"https://doi.org/10.1016/j.jfa.2020.108639\">10.1016/j.jfa.2020.108639</a>.","apa":"Bao, Z., Erdös, L., &#38; Schnelli, K. (2020). Spectral rigidity for addition of random matrices at the regular edge. <i>Journal of Functional Analysis</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.jfa.2020.108639\">https://doi.org/10.1016/j.jfa.2020.108639</a>"},"main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/1708.01597"}],"quality_controlled":"1","author":[{"id":"442E6A6C-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-3036-1475","full_name":"Bao, Zhigang","first_name":"Zhigang","last_name":"Bao"},{"first_name":"László","last_name":"Erdös","id":"4DBD5372-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-5366-9603","full_name":"Erdös, László"},{"full_name":"Schnelli, Kevin","last_name":"Schnelli","first_name":"Kevin"}],"project":[{"name":"Random matrices, universality and disordered quantum systems","grant_number":"338804","call_identifier":"FP7","_id":"258DCDE6-B435-11E9-9278-68D0E5697425"}],"abstract":[{"lang":"eng","text":"We consider the sum of two large Hermitian matrices A and B with a Haar unitary conjugation bringing them into a general relative position. We prove that the eigenvalue density on the scale slightly above the local eigenvalue spacing is asymptotically given by the free additive convolution of the laws of A and B as the dimension of the matrix increases. This implies optimal rigidity of the eigenvalues and optimal rate of convergence in Voiculescu's theorem. Our previous works [4], [5] established these results in the bulk spectrum, the current paper completely settles the problem at the spectral edges provided they have the typical square-root behavior. The key element of our proof is to compensate the deterioration of the stability of the subordination equations by sharp error estimates that properly account for the local density near the edge. Our results also hold if the Haar unitary matrix is replaced by the Haar orthogonal matrix."}],"publication_status":"published","publication":"Journal of Functional Analysis","title":"Spectral rigidity for addition of random matrices at the regular edge","_id":"10862","oa":1,"external_id":{"isi":["000559623200009"],"arxiv":["1708.01597"]},"keyword":["Analysis"],"date_published":"2020-10-15T00:00:00Z","arxiv":1,"scopus_import":"1","publication_identifier":{"issn":["0022-1236"]},"oa_version":"Preprint","type":"journal_article","date_updated":"2023-08-24T14:08:42Z","day":"15","article_processing_charge":"No","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","acknowledgement":"Partially supported by ERC Advanced Grant RANMAT No. 338804.","ec_funded":1,"department":[{"_id":"LaEr"}],"doi":"10.1016/j.jfa.2020.108639","language":[{"iso":"eng"}]},{"main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/1702.07513"}],"citation":{"mla":"Akopyan, Arseniy, and Roman Karasev. “Waist of Balls in Hyperbolic and Spherical Spaces.” <i>International Mathematics Research Notices</i>, vol. 2020, no. 3, Oxford University Press, 2020, pp. 669–97, doi:<a href=\"https://doi.org/10.1093/imrn/rny037\">10.1093/imrn/rny037</a>.","apa":"Akopyan, A., &#38; Karasev, R. (2020). Waist of balls in hyperbolic and spherical spaces. <i>International Mathematics Research Notices</i>. Oxford University Press. <a href=\"https://doi.org/10.1093/imrn/rny037\">https://doi.org/10.1093/imrn/rny037</a>","ama":"Akopyan A, Karasev R. Waist of balls in hyperbolic and spherical spaces. <i>International Mathematics Research Notices</i>. 2020;2020(3):669-697. doi:<a href=\"https://doi.org/10.1093/imrn/rny037\">10.1093/imrn/rny037</a>","ieee":"A. Akopyan and R. Karasev, “Waist of balls in hyperbolic and spherical spaces,” <i>International Mathematics Research Notices</i>, vol. 2020, no. 3. Oxford University Press, pp. 669–697, 2020.","ista":"Akopyan A, Karasev R. 2020. Waist of balls in hyperbolic and spherical spaces. International Mathematics Research Notices. 2020(3), 669–697.","chicago":"Akopyan, Arseniy, and Roman Karasev. “Waist of Balls in Hyperbolic and Spherical Spaces.” <i>International Mathematics Research Notices</i>. Oxford University Press, 2020. <a href=\"https://doi.org/10.1093/imrn/rny037\">https://doi.org/10.1093/imrn/rny037</a>.","short":"A. Akopyan, R. Karasev, International Mathematics Research Notices 2020 (2020) 669–697."},"author":[{"id":"430D2C90-F248-11E8-B48F-1D18A9856A87","full_name":"Akopyan, Arseniy","orcid":"0000-0002-2548-617X","last_name":"Akopyan","first_name":"Arseniy"},{"full_name":"Karasev, Roman","last_name":"Karasev","first_name":"Roman"}],"quality_controlled":"1","year":"2020","publication":"International Mathematics Research Notices","title":"Waist of balls in hyperbolic and spherical spaces","_id":"10867","oa":1,"abstract":[{"lang":"eng","text":"In this paper we find a tight estimate for Gromov’s waist of the balls in spaces of constant curvature, deduce the estimates for the balls in Riemannian manifolds with upper bounds on the curvature (CAT(ϰ)-spaces), and establish similar result for normed spaces."}],"publication_status":"published","volume":2020,"issue":"3","article_type":"original","publisher":"Oxford University Press","intvolume":"      2020","isi":1,"month":"02","date_created":"2022-03-18T11:39:30Z","status":"public","article_processing_charge":"No","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","oa_version":"Preprint","date_updated":"2023-08-24T14:19:55Z","type":"journal_article","day":"01","department":[{"_id":"HeEd"}],"language":[{"iso":"eng"}],"doi":"10.1093/imrn/rny037","acknowledgement":" Supported by the Russian Foundation for Basic Research grant 18-01-00036.","external_id":{"arxiv":["1702.07513"],"isi":["000522852700002"]},"keyword":["General Mathematics"],"date_published":"2020-02-01T00:00:00Z","page":"669-697","scopus_import":"1","publication_identifier":{"issn":["1073-7928"],"eissn":["1687-0247"]},"arxiv":1},{"publisher":"Elsevier BV","article_type":"original","volume":29,"issue":"16","status":"public","month":"08","date_created":"2023-01-16T09:16:33Z","intvolume":"        29","year":"2019","author":[{"full_name":"Lawrence, Emma J.","first_name":"Emma J.","last_name":"Lawrence"},{"full_name":"Gao, Hongbo","last_name":"Gao","first_name":"Hongbo"},{"full_name":"Tock, Andrew J.","last_name":"Tock","first_name":"Andrew J."},{"full_name":"Lambing, Christophe","first_name":"Christophe","last_name":"Lambing"},{"last_name":"Blackwell","first_name":"Alexander R.","full_name":"Blackwell, Alexander R."},{"full_name":"Feng, Xiaoqi","orcid":"0000-0002-4008-1234","id":"e0164712-22ee-11ed-b12a-d80fcdf35958","first_name":"Xiaoqi","last_name":"Feng"},{"full_name":"Henderson, Ian R.","last_name":"Henderson","first_name":"Ian R."}],"quality_controlled":"1","extern":"1","citation":{"apa":"Lawrence, E. J., Gao, H., Tock, A. J., Lambing, C., Blackwell, A. R., Feng, X., &#38; Henderson, I. R. (2019). Natural variation in TBP-ASSOCIATED FACTOR 4b controls meiotic crossover and germline transcription in Arabidopsis. <i>Current Biology</i>. Elsevier BV. <a href=\"https://doi.org/10.1016/j.cub.2019.06.084\">https://doi.org/10.1016/j.cub.2019.06.084</a>","mla":"Lawrence, Emma J., et al. “Natural Variation in TBP-ASSOCIATED FACTOR 4b Controls Meiotic Crossover and Germline Transcription in Arabidopsis.” <i>Current Biology</i>, vol. 29, no. 16, Elsevier BV, 2019, p. 2676–2686.e3, doi:<a href=\"https://doi.org/10.1016/j.cub.2019.06.084\">10.1016/j.cub.2019.06.084</a>.","ieee":"E. J. Lawrence <i>et al.</i>, “Natural variation in TBP-ASSOCIATED FACTOR 4b controls meiotic crossover and germline transcription in Arabidopsis,” <i>Current Biology</i>, vol. 29, no. 16. Elsevier BV, p. 2676–2686.e3, 2019.","ama":"Lawrence EJ, Gao H, Tock AJ, et al. Natural variation in TBP-ASSOCIATED FACTOR 4b controls meiotic crossover and germline transcription in Arabidopsis. <i>Current Biology</i>. 2019;29(16):2676-2686.e3. doi:<a href=\"https://doi.org/10.1016/j.cub.2019.06.084\">10.1016/j.cub.2019.06.084</a>","ista":"Lawrence EJ, Gao H, Tock AJ, Lambing C, Blackwell AR, Feng X, Henderson IR. 2019. Natural variation in TBP-ASSOCIATED FACTOR 4b controls meiotic crossover and germline transcription in Arabidopsis. Current Biology. 29(16), 2676–2686.e3.","short":"E.J. Lawrence, H. Gao, A.J. Tock, C. Lambing, A.R. Blackwell, X. Feng, I.R. Henderson, Current Biology 29 (2019) 2676–2686.e3.","chicago":"Lawrence, Emma J., Hongbo Gao, Andrew J. Tock, Christophe Lambing, Alexander R. Blackwell, Xiaoqi Feng, and Ian R. Henderson. “Natural Variation in TBP-ASSOCIATED FACTOR 4b Controls Meiotic Crossover and Germline Transcription in Arabidopsis.” <i>Current Biology</i>. Elsevier BV, 2019. <a href=\"https://doi.org/10.1016/j.cub.2019.06.084\">https://doi.org/10.1016/j.cub.2019.06.084</a>."},"abstract":[{"lang":"eng","text":"Meiotic crossover frequency varies within genomes, which influences genetic diversity and adaptation. In turn, genetic variation within populations can act to modify crossover frequency in cis and trans. To identify genetic variation that controls meiotic crossover frequency, we screened Arabidopsis accessions using fluorescent recombination reporters. We mapped a genetic modifier of crossover frequency in Col × Bur populations of Arabidopsis to a premature stop codon within TBP-ASSOCIATED FACTOR 4b (TAF4b), which encodes a subunit of the RNA polymerase II general transcription factor TFIID. The Arabidopsis taf4b mutation is a rare variant found in the British Isles, originating in South-West Ireland. Using genetics, genomics, and immunocytology, we demonstrate a genome-wide decrease in taf4b crossovers, with strongest reduction in the sub-telomeric regions. Using RNA sequencing (RNA-seq) from purified meiocytes, we show that TAF4b expression is meiocyte enriched, whereas its paralog TAF4 is broadly expressed. Consistent with the role of TFIID in promoting gene expression, RNA-seq of wild-type and taf4b meiocytes identified widespread transcriptional changes, including in genes that regulate the meiotic cell cycle and recombination. Therefore, TAF4b duplication is associated with acquisition of meiocyte-specific expression and promotion of germline transcription, which act directly or indirectly to elevate crossovers. This identifies a novel mode of meiotic recombination control via a general transcription factor."}],"publication_status":"published","_id":"12190","pmid":1,"title":"Natural variation in TBP-ASSOCIATED FACTOR 4b controls meiotic crossover and germline transcription in Arabidopsis","publication":"Current Biology","page":"2676-2686.e3","keyword":["General Agricultural and Biological Sciences","General Biochemistry","Genetics and Molecular Biology"],"external_id":{"pmid":["31378616"]},"date_published":"2019-08-19T00:00:00Z","scopus_import":"1","publication_identifier":{"issn":["0960-9822"]},"day":"19","oa_version":"None","date_updated":"2023-05-08T10:54:54Z","type":"journal_article","article_processing_charge":"No","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","acknowledgement":"We thank Gregory Copenhaver (University of North Carolina), Avraham Levy (The Weizmann Institute), and Scott Poethig (University of Pennsylvania) for FTLs; Piotr Ziolkowski for Col-420/Bur seed; Sureshkumar Balasubramanian\r\n(Monash University) for providing British and Irish Arabidopsis accessions; Mathilde Grelon (INRA, Versailles) for providing the MLH1 antibody; and the Gurdon Institute for access to microscopes. This work was supported by a BBSRC DTP studentship (E.J.L.), European Research Area Network for Coordinating Action in Plant Sciences/BBSRC ‘‘DeCOP’’ (BB/M004937/1; C.L.), a BBSRC David Phillips Fellowship (BB/L025043/1; H.G. and X.F.), the European Research Council (CoG ‘‘SynthHotspot,’’ A.J.T., C.L., and I.R.H.; StG ‘‘SexMeth,’’ X.F.), and a Sainsbury Charitable Foundation Studentship (A.R.B.).","department":[{"_id":"XiFe"}],"language":[{"iso":"eng"}],"doi":"10.1016/j.cub.2019.06.084"},{"date_published":"2019-05-28T00:00:00Z","keyword":["General Immunology and Microbiology","General Biochemistry","Genetics and Molecular Biology","General Medicine","General Neuroscience"],"external_id":{"unknown":["31135340"]},"file":[{"access_level":"open_access","checksum":"ea6b89c20d59e5eb3646916fe5d568ad","file_name":"2019_elife_He.pdf","date_updated":"2023-02-07T09:42:46Z","file_id":"12525","success":1,"file_size":2493837,"content_type":"application/pdf","creator":"alisjak","date_created":"2023-02-07T09:42:46Z","relation":"main_file"}],"publication_identifier":{"issn":["2050-084X"]},"scopus_import":"1","article_processing_charge":"No","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","type":"journal_article","date_updated":"2023-05-08T10:54:12Z","oa_version":"Published Version","day":"28","doi":"10.7554/elife.42530","language":[{"iso":"eng"}],"has_accepted_license":"1","department":[{"_id":"XiFe"}],"acknowledgement":"We thank David Twell for the pDONR-P4-P1R-pLAT52 and pDONR-P2R-P3-mRFP vectors, the John Innes Centre Bioimaging Facility (Elaine Barclay and Grant Calder) for their assistance with microscopy, and the Norwich BioScience Institute Partnership Computing infrastructure for Science Group for High Performance Computing resources. This work was funded by a Biotechnology and Biological Sciences Research Council (BBSRC) David Phillips Fellowship (BB/L025043/1; SH, JZ and XF), a European Research Council Starting Grant ('SexMeth' 804981; XF) and a Grant to Exceptional Researchers by the Gatsby Charitable Foundation (SH and XF).","volume":8,"file_date_updated":"2023-02-07T09:42:46Z","publisher":"eLife Sciences Publications, Ltd","article_type":"original","intvolume":"         8","date_created":"2023-01-16T09:17:21Z","month":"05","status":"public","article_number":"42530","main_file_link":[{"open_access":"1","url":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594752/"}],"citation":{"ieee":"S. He, M. Vickers, J. Zhang, and X. Feng, “Natural depletion of histone H1 in sex cells causes DNA demethylation, heterochromatin decondensation and transposon activation,” <i>eLife</i>, vol. 8. eLife Sciences Publications, Ltd, 2019.","ama":"He S, Vickers M, Zhang J, Feng X. Natural depletion of histone H1 in sex cells causes DNA demethylation, heterochromatin decondensation and transposon activation. <i>eLife</i>. 2019;8. doi:<a href=\"https://doi.org/10.7554/elife.42530\">10.7554/elife.42530</a>","chicago":"He, Shengbo, Martin Vickers, Jingyi Zhang, and Xiaoqi Feng. “Natural Depletion of Histone H1 in Sex Cells Causes DNA Demethylation, Heterochromatin Decondensation and Transposon Activation.” <i>ELife</i>. eLife Sciences Publications, Ltd, 2019. <a href=\"https://doi.org/10.7554/elife.42530\">https://doi.org/10.7554/elife.42530</a>.","short":"S. He, M. Vickers, J. Zhang, X. Feng, ELife 8 (2019).","ista":"He S, Vickers M, Zhang J, Feng X. 2019. Natural depletion of histone H1 in sex cells causes DNA demethylation, heterochromatin decondensation and transposon activation. eLife. 8, 42530.","mla":"He, Shengbo, et al. “Natural Depletion of Histone H1 in Sex Cells Causes DNA Demethylation, Heterochromatin Decondensation and Transposon Activation.” <i>ELife</i>, vol. 8, 42530, eLife Sciences Publications, Ltd, 2019, doi:<a href=\"https://doi.org/10.7554/elife.42530\">10.7554/elife.42530</a>.","apa":"He, S., Vickers, M., Zhang, J., &#38; Feng, X. (2019). Natural depletion of histone H1 in sex cells causes DNA demethylation, heterochromatin decondensation and transposon activation. <i>ELife</i>. eLife Sciences Publications, Ltd. <a href=\"https://doi.org/10.7554/elife.42530\">https://doi.org/10.7554/elife.42530</a>"},"quality_controlled":"1","author":[{"full_name":"He, Shengbo","first_name":"Shengbo","last_name":"He"},{"first_name":"Martin","last_name":"Vickers","full_name":"Vickers, Martin"},{"full_name":"Zhang, Jingyi","last_name":"Zhang","first_name":"Jingyi"},{"full_name":"Feng, Xiaoqi","orcid":"0000-0002-4008-1234","id":"e0164712-22ee-11ed-b12a-d80fcdf35958","last_name":"Feng","first_name":"Xiaoqi"}],"extern":"1","tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"year":"2019","title":"Natural depletion of histone H1 in sex cells causes DNA demethylation, heterochromatin decondensation and transposon activation","publication":"eLife","oa":1,"ddc":["580"],"_id":"12192","publication_status":"published","abstract":[{"lang":"eng","text":"Transposable elements (TEs), the movement of which can damage the genome, are epigenetically silenced in eukaryotes. Intriguingly, TEs are activated in the sperm companion cell – vegetative cell (VC) – of the flowering plant Arabidopsis thaliana. However, the extent and mechanism of this activation are unknown. Here we show that about 100 heterochromatic TEs are activated in VCs, mostly by DEMETER-catalyzed DNA demethylation. We further demonstrate that DEMETER access to some of these TEs is permitted by the natural depletion of linker histone H1 in VCs. Ectopically expressed H1 suppresses TEs in VCs by reducing DNA demethylation and via a methylation-independent mechanism. We demonstrate that H1 is required for heterochromatin condensation in plant cells and show that H1 overexpression creates heterochromatic foci in the VC progenitor cell. Taken together, our results demonstrate that the natural depletion of H1 during male gametogenesis facilitates DEMETER-directed DNA demethylation, heterochromatin relaxation, and TE activation."}]},{"publisher":"Dryad","date_published":"2019-12-02T00:00:00Z","status":"public","month":"12","date_created":"2023-05-23T16:36:27Z","year":"2019","day":"02","oa_version":"Published Version","tmp":{"short":"CC0 (1.0)","legal_code_url":"https://creativecommons.org/publicdomain/zero/1.0/legalcode","name":"Creative Commons Public Domain Dedication (CC0 1.0)","image":"/images/cc_0.png"},"type":"research_data_reference","date_updated":"2023-09-06T14:48:57Z","author":[{"full_name":"Johannesson, Kerstin","last_name":"Johannesson","first_name":"Kerstin"},{"last_name":"Zagrodzka","first_name":"Zuzanna","full_name":"Zagrodzka, Zuzanna"},{"full_name":"Faria, Rui","first_name":"Rui","last_name":"Faria"},{"first_name":"Anja M","last_name":"Westram","orcid":"0000-0003-1050-4969","full_name":"Westram, Anja M","id":"3C147470-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Butlin, Roger","first_name":"Roger","last_name":"Butlin"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_processing_charge":"No","main_file_link":[{"open_access":"1","url":"https://doi.org/10.5061/dryad.tb2rbnzwk"}],"citation":{"ama":"Johannesson K, Zagrodzka Z, Faria R, Westram AM, Butlin R. Data from: Is embryo abortion a postzygotic barrier to gene flow between Littorina ecotypes? 2019. doi:<a href=\"https://doi.org/10.5061/DRYAD.TB2RBNZWK\">10.5061/DRYAD.TB2RBNZWK</a>","ieee":"K. Johannesson, Z. Zagrodzka, R. Faria, A. M. Westram, and R. Butlin, “Data from: Is embryo abortion a postzygotic barrier to gene flow between Littorina ecotypes?” Dryad, 2019.","ista":"Johannesson K, Zagrodzka Z, Faria R, Westram AM, Butlin R. 2019. Data from: Is embryo abortion a postzygotic barrier to gene flow between Littorina ecotypes?, Dryad, <a href=\"https://doi.org/10.5061/DRYAD.TB2RBNZWK\">10.5061/DRYAD.TB2RBNZWK</a>.","short":"K. Johannesson, Z. Zagrodzka, R. Faria, A.M. Westram, R. Butlin, (2019).","chicago":"Johannesson, Kerstin, Zuzanna Zagrodzka, Rui Faria, Anja M Westram, and Roger Butlin. “Data from: Is Embryo Abortion a Postzygotic Barrier to Gene Flow between Littorina Ecotypes?” Dryad, 2019. <a href=\"https://doi.org/10.5061/DRYAD.TB2RBNZWK\">https://doi.org/10.5061/DRYAD.TB2RBNZWK</a>.","apa":"Johannesson, K., Zagrodzka, Z., Faria, R., Westram, A. M., &#38; Butlin, R. (2019). Data from: Is embryo abortion a postzygotic barrier to gene flow between Littorina ecotypes? Dryad. <a href=\"https://doi.org/10.5061/DRYAD.TB2RBNZWK\">https://doi.org/10.5061/DRYAD.TB2RBNZWK</a>","mla":"Johannesson, Kerstin, et al. <i>Data from: Is Embryo Abortion a Postzygotic Barrier to Gene Flow between Littorina Ecotypes?</i> Dryad, 2019, doi:<a href=\"https://doi.org/10.5061/DRYAD.TB2RBNZWK\">10.5061/DRYAD.TB2RBNZWK</a>."},"abstract":[{"lang":"eng","text":"Genetic incompatibilities contribute to reproductive isolation between many diverging populations, but it is still unclear to what extent they play a role if divergence happens with gene flow. In contact zones between the \"Crab\" and \"Wave\" ecotypes of the snail Littorina saxatilis divergent selection forms strong barriers to gene flow, while the role of postzygotic barriers due to selection against hybrids remains unclear. High embryo abortion rates in this species could indicate the presence of such barriers. Postzygotic barriers might include genetic incompatibilities (e.g. Dobzhansky-Muller incompatibilities) but also maladaptation, both expected to be most pronounced in contact zones. In addition, embryo abortion might reflect physiological stress on females and embryos independent of any genetic stress. We examined all embryos of &gt;500 females sampled outside and inside contact zones of three populations in Sweden. Females' clutch size ranged from 0 to 1011 embryos (mean 130±123) and abortion rates varied between 0 and100% (mean 12%). We described female genotypes by using a hybrid index based on hundreds of SNPs differentiated between ecotypes with which we characterised female genotypes. We also calculated female SNP heterozygosity and inversion karyotype. Clutch size did not vary with female hybrid index and abortion rates were only weakly related to hybrid index in two sites but not at all in a third site. No additional variation in abortion rate was explained by female SNP heterozygosity, but increased female inversion heterozygosity added slightly to increased abortion. Our results show only weak and probably biologically insignificant postzygotic barriers contributing to ecotype divergence and the high and variable abortion rates were marginally, if at all, explained by hybrid index of females."}],"department":[{"_id":"NiBa"}],"_id":"13067","license":"https://creativecommons.org/publicdomain/zero/1.0/","related_material":{"record":[{"status":"public","relation":"used_in_publication","id":"7205"}]},"ddc":["570"],"doi":"10.5061/DRYAD.TB2RBNZWK","oa":1,"title":"Data from: Is embryo abortion a postzygotic barrier to gene flow between Littorina ecotypes?"},{"user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","article_processing_charge":"No","oa_version":"None","date_updated":"2023-09-08T11:24:15Z","type":"book_chapter","day":"29","edition":"4","department":[{"_id":"NiBa"}],"doi":"10.1002/9781119487845.ch4","language":[{"iso":"eng"}],"external_id":{"isi":["000261343000003"]},"date_published":"2019-07-29T00:00:00Z","page":"115-144","publication_identifier":{"isbn":["9781119429142"]},"citation":{"mla":"Barton, Nicholas H., and Alison Etheridge. “Mathematical Models in Population Genetics.” <i>Handbook of Statistical Genomics</i>, edited by David Balding et al., 4th ed., Wiley, 2019, pp. 115–44, doi:<a href=\"https://doi.org/10.1002/9781119487845.ch4\">10.1002/9781119487845.ch4</a>.","apa":"Barton, N. H., &#38; Etheridge, A. (2019). Mathematical models in population genetics. In D. Balding, I. Moltke, &#38; J. Marioni (Eds.), <i>Handbook of statistical genomics</i> (4th ed., pp. 115–144). Wiley. <a href=\"https://doi.org/10.1002/9781119487845.ch4\">https://doi.org/10.1002/9781119487845.ch4</a>","ista":"Barton NH, Etheridge A. 2019.Mathematical models in population genetics. In: Handbook of statistical genomics. , 115–144.","short":"N.H. Barton, A. Etheridge, in:, D. Balding, I. Moltke, J. Marioni (Eds.), Handbook of Statistical Genomics, 4th ed., Wiley, 2019, pp. 115–144.","chicago":"Barton, Nicholas H, and Alison Etheridge. “Mathematical Models in Population Genetics.” In <i>Handbook of Statistical Genomics</i>, edited by David Balding, Ida Moltke, and John Marioni, 4th ed., 115–44. Wiley, 2019. <a href=\"https://doi.org/10.1002/9781119487845.ch4\">https://doi.org/10.1002/9781119487845.ch4</a>.","ama":"Barton NH, Etheridge A. Mathematical models in population genetics. In: Balding D, Moltke I, Marioni J, eds. <i>Handbook of Statistical Genomics</i>. 4th ed. Wiley; 2019:115-144. doi:<a href=\"https://doi.org/10.1002/9781119487845.ch4\">10.1002/9781119487845.ch4</a>","ieee":"N. H. Barton and A. Etheridge, “Mathematical models in population genetics,” in <i>Handbook of statistical genomics</i>, 4th ed., D. Balding, I. Moltke, and J. Marioni, Eds. Wiley, 2019, pp. 115–144."},"quality_controlled":"1","author":[{"id":"4880FE40-F248-11E8-B48F-1D18A9856A87","full_name":"Barton, Nicholas H","orcid":"0000-0002-8548-5240","first_name":"Nicholas H","last_name":"Barton"},{"full_name":"Etheridge, Alison","first_name":"Alison","last_name":"Etheridge"}],"year":"2019","publication":"Handbook of statistical genomics","title":"Mathematical models in population genetics","_id":"8281","ddc":["576"],"abstract":[{"lang":"eng","text":"We review the history of population genetics, starting with its origins a century ago from the synthesis between Mendel and Darwin's ideas, through to the recent development of sophisticated schemes of inference from sequence data, based on the coalescent. We explain the close relation between the coalescent and a diffusion process, which we illustrate by their application to understand spatial structure. We summarise the powerful methods available for analysis of multiple loci, when linkage equilibrium can be assumed, and then discuss approaches to the more challenging case, where associations between alleles require that we follow genotype, rather than allele, frequencies. Though we can hardly cover the whole of population genetics, we give an overview of the current state of the subject, and future challenges to it."}],"publication_status":"published","editor":[{"first_name":"David","last_name":"Balding","full_name":"Balding, David"},{"last_name":"Moltke","first_name":"Ida","full_name":"Moltke, Ida"},{"first_name":"John","last_name":"Marioni","full_name":"Marioni, John"}],"publisher":"Wiley","isi":1,"month":"07","date_created":"2020-08-21T04:25:39Z","status":"public"},{"publication":"EPiC Series in Computing","title":"ARCH-COMP19 Category Report: Continuous and hybrid systems with linear continuous dynamics","_id":"8570","department":[{"_id":"ToHe"}],"oa":1,"language":[{"iso":"eng"}],"doi":"10.29007/bj1w","abstract":[{"lang":"eng","text":"This report presents the results of a friendly competition for formal verification of continuous and hybrid systems with linear continuous dynamics. The friendly competition took place as part of the workshop Applied Verification for Continuous and Hybrid Systems (ARCH) in 2019. In its third edition, seven tools have been applied to solve six different benchmark problems in the category for linear continuous dynamics (in alphabetical order): CORA, CORA/SX, HyDRA, Hylaa, JuliaReach, SpaceEx, and XSpeed. This report is a snapshot of the current landscape of tools and the types of benchmarks they are particularly suited for. Due to the diversity of problems, we are not ranking tools, yet the presented results provide one of the most complete assessments of tools for the safety verification of continuous and hybrid systems with linear continuous dynamics up to this date.</jats:p>"}],"publication_status":"published","main_file_link":[{"open_access":"1","url":"https://easychair.org/publications/open/1gbP"}],"citation":{"ista":"Althoff M, Bak S, Forets M, Frehse G, Kochdumper N, Ray R, Schilling C, Schupp S. 2019. ARCH-COMP19 Category Report: Continuous and hybrid systems with linear continuous dynamics. EPiC Series in Computing. ARCH: International Workshop on Applied Verification on Continuous and Hybrid Systems vol. 61, 14–40.","chicago":"Althoff, Matthias, Stanley Bak, Marcelo Forets, Goran Frehse, Niklas Kochdumper, Rajarshi Ray, Christian Schilling, and Stefan Schupp. “ARCH-COMP19 Category Report: Continuous and Hybrid Systems with Linear Continuous Dynamics.” In <i>EPiC Series in Computing</i>, 61:14–40. EasyChair, 2019. <a href=\"https://doi.org/10.29007/bj1w\">https://doi.org/10.29007/bj1w</a>.","short":"M. Althoff, S. Bak, M. Forets, G. Frehse, N. Kochdumper, R. Ray, C. Schilling, S. Schupp, in:, EPiC Series in Computing, EasyChair, 2019, pp. 14–40.","ama":"Althoff M, Bak S, Forets M, et al. ARCH-COMP19 Category Report: Continuous and hybrid systems with linear continuous dynamics. In: <i>EPiC Series in Computing</i>. Vol 61. EasyChair; 2019:14-40. doi:<a href=\"https://doi.org/10.29007/bj1w\">10.29007/bj1w</a>","ieee":"M. Althoff <i>et al.</i>, “ARCH-COMP19 Category Report: Continuous and hybrid systems with linear continuous dynamics,” in <i>EPiC Series in Computing</i>, Montreal, Canada, 2019, vol. 61, pp. 14–40.","mla":"Althoff, Matthias, et al. “ARCH-COMP19 Category Report: Continuous and Hybrid Systems with Linear Continuous Dynamics.” <i>EPiC Series in Computing</i>, vol. 61, EasyChair, 2019, pp. 14–40, doi:<a href=\"https://doi.org/10.29007/bj1w\">10.29007/bj1w</a>.","apa":"Althoff, M., Bak, S., Forets, M., Frehse, G., Kochdumper, N., Ray, R., … Schupp, S. (2019). ARCH-COMP19 Category Report: Continuous and hybrid systems with linear continuous dynamics. In <i>EPiC Series in Computing</i> (Vol. 61, pp. 14–40). Montreal, Canada: EasyChair. <a href=\"https://doi.org/10.29007/bj1w\">https://doi.org/10.29007/bj1w</a>"},"author":[{"full_name":"Althoff, Matthias","first_name":"Matthias","last_name":"Althoff"},{"full_name":"Bak, Stanley","last_name":"Bak","first_name":"Stanley"},{"last_name":"Forets","first_name":"Marcelo","full_name":"Forets, Marcelo"},{"first_name":"Goran","last_name":"Frehse","full_name":"Frehse, Goran"},{"full_name":"Kochdumper, Niklas","last_name":"Kochdumper","first_name":"Niklas"},{"full_name":"Ray, Rajarshi","first_name":"Rajarshi","last_name":"Ray"},{"full_name":"Schilling, Christian","orcid":"0000-0003-3658-1065","id":"3A2F4DCE-F248-11E8-B48F-1D18A9856A87","last_name":"Schilling","first_name":"Christian"},{"last_name":"Schupp","first_name":"Stefan","full_name":"Schupp, Stefan"}],"article_processing_charge":"No","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","quality_controlled":"1","oa_version":"Published Version","date_updated":"2021-01-12T08:20:05Z","type":"conference","year":"2019","day":"25","intvolume":"        61","publication_identifier":{"eissn":["23987340"]},"month":"05","conference":{"name":"ARCH: International Workshop on Applied Verification on Continuous and Hybrid Systems","end_date":"2019-04-15","start_date":"2019-04-15","location":"Montreal, Canada"},"date_created":"2020-09-26T14:23:54Z","status":"public","date_published":"2019-05-25T00:00:00Z","volume":61,"page":"14-40","publisher":"EasyChair"},{"status":"public","date_created":"2021-03-21T23:01:21Z","conference":{"name":"IASS: International Association for Shell and Spatial Structures","end_date":"2019-10-10","start_date":"2019-10-07","location":"Barcelona, Spain"},"month":"10","publication_identifier":{"isbn":["9788412110104"],"issn":["2518-6582"]},"isi":1,"scopus_import":"1","publisher":"International Center for Numerical Methods in Engineering","page":"509-515","date_published":"2019-10-10T00:00:00Z","external_id":{"isi":["000563497600059"]},"publication_status":"published","abstract":[{"lang":"eng","text":"Bending-active structures are able to efficiently produce complex curved shapes starting from flat panels. The desired deformation of the panels derives from the proper selection of their elastic properties. Optimized panels, called FlexMaps, are designed such that, once they are bent and assembled, the resulting static equilibrium configuration matches a desired input 3D shape. The FlexMaps elastic properties are controlled by locally varying spiraling geometric mesostructures, which are optimized in size and shape to match the global curvature (i.e., bending requests) of the target shape. The design pipeline starts from a quad mesh representing the input 3D shape, which defines the edge size and the total amount of spirals: every quad will embed one spiral. Then, an optimization algorithm tunes the geometry of the spirals by using a simplified pre-computed rod model. This rod model is derived from a non-linear regression algorithm which approximates the non-linear behavior of solid FEM spiral models subject to hundreds of load combinations. This innovative pipeline has been applied to the project of a lightweight plywood pavilion named FlexMaps Pavilion, which is a single-layer piecewise twisted arc that fits a bounding box of 3.90x3.96x3.25 meters."}],"language":[{"iso":"eng"}],"department":[{"_id":"BeBi"}],"_id":"9261","title":"FlexMaps Pavilion: A twisted arc made of mesostructured flat flexible panels","publication":"IASS Symposium 2019 - 60th Anniversary Symposium of the International Association for Shell and Spatial Structures; Structural Membranes 2019 - 9th International Conference on Textile Composites and Inflatable Structures, FORM and FORCE","day":"10","year":"2019","date_updated":"2023-09-08T11:21:54Z","type":"conference","oa_version":"None","quality_controlled":"1","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","article_processing_charge":"No","author":[{"last_name":"Laccone","first_name":"Francesco","full_name":"Laccone, Francesco"},{"full_name":"Malomo, Luigi","first_name":"Luigi","last_name":"Malomo"},{"id":"2DC83906-F248-11E8-B48F-1D18A9856A87","full_name":"Perez Rodriguez, Jesus","last_name":"Perez Rodriguez","first_name":"Jesus"},{"last_name":"Pietroni","first_name":"Nico","full_name":"Pietroni, Nico"},{"first_name":"Federico","last_name":"Ponchio","full_name":"Ponchio, Federico"},{"orcid":"0000-0001-6511-9385","full_name":"Bickel, Bernd","id":"49876194-F248-11E8-B48F-1D18A9856A87","last_name":"Bickel","first_name":"Bernd"},{"first_name":"Paolo","last_name":"Cignoni","full_name":"Cignoni, Paolo"}],"citation":{"ieee":"F. Laccone <i>et al.</i>, “FlexMaps Pavilion: A twisted arc made of mesostructured flat flexible panels,” in <i>IASS Symposium 2019 - 60th Anniversary Symposium of the International Association for Shell and Spatial Structures; Structural Membranes 2019 - 9th International Conference on Textile Composites and Inflatable Structures, FORM and FORCE</i>, Barcelona, Spain, 2019, pp. 509–515.","ama":"Laccone F, Malomo L, Perez Rodriguez J, et al. FlexMaps Pavilion: A twisted arc made of mesostructured flat flexible panels. In: <i>IASS Symposium 2019 - 60th Anniversary Symposium of the International Association for Shell and Spatial Structures; Structural Membranes 2019 - 9th International Conference on Textile Composites and Inflatable Structures, FORM and FORCE</i>. International Center for Numerical Methods in Engineering; 2019:509-515.","chicago":"Laccone, Francesco, Luigi Malomo, Jesus Perez Rodriguez, Nico Pietroni, Federico Ponchio, Bernd Bickel, and Paolo Cignoni. “FlexMaps Pavilion: A Twisted Arc Made of Mesostructured Flat Flexible Panels.” In <i>IASS Symposium 2019 - 60th Anniversary Symposium of the International Association for Shell and Spatial Structures; Structural Membranes 2019 - 9th International Conference on Textile Composites and Inflatable Structures, FORM and FORCE</i>, 509–15. International Center for Numerical Methods in Engineering, 2019.","short":"F. Laccone, L. Malomo, J. Perez Rodriguez, N. Pietroni, F. Ponchio, B. Bickel, P. Cignoni, in:, IASS Symposium 2019 - 60th Anniversary Symposium of the International Association for Shell and Spatial Structures; Structural Membranes 2019 - 9th International Conference on Textile Composites and Inflatable Structures, FORM and FORCE, International Center for Numerical Methods in Engineering, 2019, pp. 509–515.","ista":"Laccone F, Malomo L, Perez Rodriguez J, Pietroni N, Ponchio F, Bickel B, Cignoni P. 2019. FlexMaps Pavilion: A twisted arc made of mesostructured flat flexible panels. IASS Symposium 2019 - 60th Anniversary Symposium of the International Association for Shell and Spatial Structures; Structural Membranes 2019 - 9th International Conference on Textile Composites and Inflatable Structures, FORM and FORCE. IASS: International Association for Shell and Spatial Structures, 509–515.","apa":"Laccone, F., Malomo, L., Perez Rodriguez, J., Pietroni, N., Ponchio, F., Bickel, B., &#38; Cignoni, P. (2019). FlexMaps Pavilion: A twisted arc made of mesostructured flat flexible panels. In <i>IASS Symposium 2019 - 60th Anniversary Symposium of the International Association for Shell and Spatial Structures; Structural Membranes 2019 - 9th International Conference on Textile Composites and Inflatable Structures, FORM and FORCE</i> (pp. 509–515). Barcelona, Spain: International Center for Numerical Methods in Engineering.","mla":"Laccone, Francesco, et al. “FlexMaps Pavilion: A Twisted Arc Made of Mesostructured Flat Flexible Panels.” <i>IASS Symposium 2019 - 60th Anniversary Symposium of the International Association for Shell and Spatial Structures; Structural Membranes 2019 - 9th International Conference on Textile Composites and Inflatable Structures, FORM and FORCE</i>, International Center for Numerical Methods in Engineering, 2019, pp. 509–15."}},{"_id":"6919","oa":1,"ddc":["570"],"title":"Structural basis of sterol recognition by human hedgehog receptor PTCH1","publication":"Science Advances","publication_status":"published","quality_controlled":"1","author":[{"last_name":"Qi","first_name":"Chao","full_name":"Qi, Chao"},{"first_name":"Giulio Di","last_name":"Minin","full_name":"Minin, Giulio Di"},{"orcid":"0000-0001-5618-3449","full_name":"Vercellino, Irene","id":"3ED6AF16-F248-11E8-B48F-1D18A9856A87","last_name":"Vercellino","first_name":"Irene"},{"full_name":"Wutz, Anton","first_name":"Anton","last_name":"Wutz"},{"first_name":"Volodymyr M.","last_name":"Korkhov","full_name":"Korkhov, Volodymyr M."}],"citation":{"short":"C. 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