[{"date_updated":"2024-03-05T09:33:38Z","_id":"14846","project":[{"grant_number":"I03601","name":"Control of embryonic cleavage pattern","call_identifier":"FWF","_id":"2646861A-B435-11E9-9278-68D0E5697425"}],"department":[{"_id":"CaHe"},{"_id":"JoFi"},{"_id":"MiSi"},{"_id":"EM-Fac"},{"_id":"NanoFab"}],"citation":{"ieee":"S. Caballero Mancebo <i>et al.</i>, “Friction forces determine cytoplasmic reorganization and shape changes of ascidian oocytes upon fertilization,” <i>Nature Physics</i>. Springer Nature, 2024.","mla":"Caballero Mancebo, Silvia, et al. “Friction Forces Determine Cytoplasmic Reorganization and Shape Changes of Ascidian Oocytes upon Fertilization.” <i>Nature Physics</i>, Springer Nature, 2024, doi:<a href=\"https://doi.org/10.1038/s41567-023-02302-1\">10.1038/s41567-023-02302-1</a>.","ama":"Caballero Mancebo S, Shinde R, Bolger-Munro M, et al. Friction forces determine cytoplasmic reorganization and shape changes of ascidian oocytes upon fertilization. <i>Nature Physics</i>. 2024. doi:<a href=\"https://doi.org/10.1038/s41567-023-02302-1\">10.1038/s41567-023-02302-1</a>","chicago":"Caballero Mancebo, Silvia, Rushikesh Shinde, Madison Bolger-Munro, Matilda Peruzzo, Gregory Szep, Irene Steccari, David Labrousse Arias, et al. “Friction Forces Determine Cytoplasmic Reorganization and Shape Changes of Ascidian Oocytes upon Fertilization.” <i>Nature Physics</i>. Springer Nature, 2024. <a href=\"https://doi.org/10.1038/s41567-023-02302-1\">https://doi.org/10.1038/s41567-023-02302-1</a>.","apa":"Caballero Mancebo, S., Shinde, R., Bolger-Munro, M., Peruzzo, M., Szep, G., Steccari, I., … Heisenberg, C.-P. J. (2024). Friction forces determine cytoplasmic reorganization and shape changes of ascidian oocytes upon fertilization. <i>Nature Physics</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41567-023-02302-1\">https://doi.org/10.1038/s41567-023-02302-1</a>","ista":"Caballero Mancebo S, Shinde R, Bolger-Munro M, Peruzzo M, Szep G, Steccari I, Labrousse Arias D, Zheden V, Merrin J, Callan-Jones A, Voituriez R, Heisenberg C-PJ. 2024. Friction forces determine cytoplasmic reorganization and shape changes of ascidian oocytes upon fertilization. Nature Physics.","short":"S. Caballero Mancebo, R. Shinde, M. Bolger-Munro, M. Peruzzo, G. Szep, I. Steccari, D. Labrousse Arias, V. Zheden, J. Merrin, A. Callan-Jones, R. Voituriez, C.-P.J. Heisenberg, Nature Physics (2024)."},"publication_status":"epub_ahead","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1038/s41567-023-02302-1"}],"date_created":"2024-01-21T23:00:57Z","title":"Friction forces determine cytoplasmic reorganization and shape changes of ascidian oocytes upon fertilization","day":"09","acknowledgement":"We would like to thank A. McDougall, E. Hannezo and the Heisenberg lab for fruitful discussions and reagents. We also thank E. Munro for the iMyo-YFP and Bra>iMyo-mScarlet constructs. This research was supported by the Scientific Service Units of the Institute of Science and Technology Austria through resources provided by the Electron Microscopy Facility, Imaging and Optics Facility and the Nanofabrication Facility. This work was supported by a Joint Project Grant from the FWF (I 3601-B27).","year":"2024","doi":"10.1038/s41567-023-02302-1","type":"journal_article","publication_identifier":{"eissn":["1745-2481"],"issn":["1745-2473"]},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","acknowledged_ssus":[{"_id":"EM-Fac"},{"_id":"Bio"},{"_id":"NanoFab"}],"related_material":{"link":[{"description":"News on ISTA Website","relation":"press_release","url":"https://ista.ac.at/en/news/stranger-than-friction-a-force-initiating-life/"}]},"language":[{"iso":"eng"}],"publication":"Nature Physics","oa_version":"Published Version","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"publisher":"Springer Nature","oa":1,"status":"public","article_type":"original","quality_controlled":"1","abstract":[{"text":"Contraction and flow of the actin cell cortex have emerged as a common principle by which cells reorganize their cytoplasm and take shape. However, how these cortical flows interact with adjacent cytoplasmic components, changing their form and localization, and how this affects cytoplasmic organization and cell shape remains unclear. Here we show that in ascidian oocytes, the cooperative activities of cortical actomyosin flows and deformation of the adjacent mitochondria-rich myoplasm drive oocyte cytoplasmic reorganization and shape changes following fertilization. We show that vegetal-directed cortical actomyosin flows, established upon oocyte fertilization, lead to both the accumulation of cortical actin at the vegetal pole of the zygote and compression and local buckling of the adjacent elastic solid-like myoplasm layer due to friction forces generated at their interface. Once cortical flows have ceased, the multiple myoplasm buckles resolve into one larger buckle, which again drives the formation of the contraction pole—a protuberance of the zygote’s vegetal pole where maternal mRNAs accumulate. Thus, our findings reveal a mechanism where cortical actomyosin network flows determine cytoplasmic reorganization and cell shape by deforming adjacent cytoplasmic components through friction forces.","lang":"eng"}],"date_published":"2024-01-09T00:00:00Z","article_processing_charge":"Yes (in subscription journal)","scopus_import":"1","month":"01","author":[{"first_name":"Silvia","orcid":"0000-0002-5223-3346","id":"2F1E1758-F248-11E8-B48F-1D18A9856A87","last_name":"Caballero Mancebo","full_name":"Caballero Mancebo, Silvia"},{"first_name":"Rushikesh","full_name":"Shinde, Rushikesh","last_name":"Shinde"},{"first_name":"Madison","orcid":"0000-0002-8176-4824","id":"516F03FA-93A3-11EA-A7C5-D6BE3DDC885E","last_name":"Bolger-Munro","full_name":"Bolger-Munro, Madison"},{"last_name":"Peruzzo","full_name":"Peruzzo, Matilda","first_name":"Matilda","id":"3F920B30-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-3415-4628"},{"full_name":"Szep, Gregory","last_name":"Szep","id":"4BFB7762-F248-11E8-B48F-1D18A9856A87","first_name":"Gregory"},{"id":"2705C766-9FE2-11EA-B224-C6773DDC885E","first_name":"Irene","full_name":"Steccari, Irene","last_name":"Steccari"},{"first_name":"David","id":"CD573DF4-9ED3-11E9-9D77-3223E6697425","last_name":"Labrousse Arias","full_name":"Labrousse Arias, David"},{"first_name":"Vanessa","orcid":"0000-0002-9438-4783","id":"39C5A68A-F248-11E8-B48F-1D18A9856A87","last_name":"Zheden","full_name":"Zheden, Vanessa"},{"full_name":"Merrin, Jack","last_name":"Merrin","orcid":"0000-0001-5145-4609","id":"4515C308-F248-11E8-B48F-1D18A9856A87","first_name":"Jack"},{"first_name":"Andrew","last_name":"Callan-Jones","full_name":"Callan-Jones, Andrew"},{"first_name":"Raphaël","last_name":"Voituriez","full_name":"Voituriez, Raphaël"},{"last_name":"Heisenberg","full_name":"Heisenberg, Carl-Philipp J","first_name":"Carl-Philipp J","orcid":"0000-0002-0912-4566","id":"39427864-F248-11E8-B48F-1D18A9856A87"}],"has_accepted_license":"1"},{"citation":{"ieee":"A. Pal, M. Joshi, and M. Thaker, “Too much information? Males convey parasite levels using more signal modalities than females utilise,” <i>Journal of Experimental Biology</i>, vol. 227, no. 1. The Company of Biologists, 2024.","apa":"Pal, A., Joshi, M., &#38; Thaker, M. (2024). Too much information? Males convey parasite levels using more signal modalities than females utilise. <i>Journal of Experimental Biology</i>. The Company of Biologists. <a href=\"https://doi.org/10.1242/jeb.246217\">https://doi.org/10.1242/jeb.246217</a>","ista":"Pal A, Joshi M, Thaker M. 2024. Too much information? Males convey parasite levels using more signal modalities than females utilise. Journal of Experimental Biology. 227(1), jeb246217.","short":"A. Pal, M. Joshi, M. Thaker, Journal of Experimental Biology 227 (2024).","ama":"Pal A, Joshi M, Thaker M. Too much information? Males convey parasite levels using more signal modalities than females utilise. <i>Journal of Experimental Biology</i>. 2024;227(1). doi:<a href=\"https://doi.org/10.1242/jeb.246217\">10.1242/jeb.246217</a>","mla":"Pal, Arka, et al. “Too Much Information? Males Convey Parasite Levels Using More Signal Modalities than Females Utilise.” <i>Journal of Experimental Biology</i>, vol. 227, no. 1, jeb246217, The Company of Biologists, 2024, doi:<a href=\"https://doi.org/10.1242/jeb.246217\">10.1242/jeb.246217</a>.","chicago":"Pal, Arka, Mihir Joshi, and Maria Thaker. “Too Much Information? Males Convey Parasite Levels Using More Signal Modalities than Females Utilise.” <i>Journal of Experimental Biology</i>. The Company of Biologists, 2024. <a href=\"https://doi.org/10.1242/jeb.246217\">https://doi.org/10.1242/jeb.246217</a>."},"department":[{"_id":"NiBa"}],"file_date_updated":"2024-01-23T12:08:24Z","_id":"14850","date_updated":"2024-01-23T12:13:08Z","pmid":1,"date_created":"2024-01-22T08:14:49Z","publication_status":"published","volume":227,"acknowledgement":"We thank Anuradha Batabyal and Shakilur Kabir for scientific discussions, and help with sampling and colour analyses. We thank Muralidhar and the central LCMS facility of the IISc for their technical support with the GCMS.\r\nResearch funding was provided by the Department of Science and Technology Fund for Improvement of S&T Infrastructure (DST-FIST), the Department of Biotechnology-Indian Institute of Science (DBT-IISc) partnership program and a Science and Engineering Research Board (SERB) grant to M.T. (EMR/2017/002228). Open Access funding provided by Indian Institute of Science. Deposited in PMC for immediate release.","day":"10","title":"Too much information? Males convey parasite levels using more signal modalities than females utilise","external_id":{"pmid":["38054353"]},"issue":"1","year":"2024","publication":"Journal of Experimental Biology","oa_version":"Published Version","language":[{"iso":"eng"}],"related_material":{"link":[{"relation":"software","url":"https://github.com/arka-pal/Cnemaspis-SexualSignaling"}]},"keyword":["Insect Science","Molecular Biology","Animal Science and Zoology","Aquatic Science","Physiology","Ecology","Evolution","Behavior and Systematics"],"publication_identifier":{"issn":["1477-9145"],"eissn":["0022-0949"]},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","type":"journal_article","doi":"10.1242/jeb.246217","intvolume":"       227","publisher":"The Company of Biologists","oa":1,"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"date_published":"2024-01-10T00:00:00Z","abstract":[{"lang":"eng","text":"Elaborate sexual signals are thought to have evolved and be maintained to serve as honest indicators of signaller quality. One measure of quality is health, which can be affected by parasite infection. Cnemaspis mysoriensis is a diurnal gecko that is often infested with ectoparasites in the wild, and males of this species express visual (coloured gular patches) and chemical (femoral gland secretions) traits that receivers could assess during social interactions. In this paper, we tested whether ectoparasites affect individual health, and whether signal quality is an indicator of ectoparasite levels. In wild lizards, we found that ectoparasite level was negatively correlated with body condition in both sexes. Moreover, some characteristics of both visual and chemical traits in males were strongly associated with ectoparasite levels. Specifically, males with higher ectoparasite levels had yellow gular patches with lower brightness and chroma, and chemical secretions with a lower proportion of aromatic compounds. We then determined whether ectoparasite levels in males influence female behaviour. Using sequential choice trials, wherein females were provided with either the visual or the chemical signals of wild-caught males that varied in ectoparasite level, we found that only chemical secretions evoked an elevated female response towards less parasitised males. Simultaneous choice trials in which females were exposed to the chemical secretions from males that varied in parasite level further confirmed a preference for males with lower parasites loads. Overall, we find that although health (body condition) or ectoparasite load can be honestly advertised through multiple modalities, the parasite-mediated female response is exclusively driven by chemical signals.</jats:p>"}],"ddc":["570"],"file":[{"success":1,"date_updated":"2024-01-23T12:08:24Z","file_name":"2024_JourExperimBiology_Pal.pdf","file_size":594128,"access_level":"open_access","content_type":"application/pdf","file_id":"14877","creator":"dernst","checksum":"136325372f6f45abaa62a71e2d23bfb6","relation":"main_file","date_created":"2024-01-23T12:08:24Z"}],"quality_controlled":"1","article_type":"original","status":"public","article_number":"jeb246217","has_accepted_license":"1","author":[{"first_name":"Arka","orcid":"0000-0002-4530-8469","id":"6AAB2240-CA9A-11E9-9C1A-D9D1E5697425","last_name":"Pal","full_name":"Pal, Arka"},{"last_name":"Joshi","full_name":"Joshi, Mihir","first_name":"Mihir"},{"last_name":"Thaker","full_name":"Thaker, Maria","first_name":"Maria"}],"month":"01","article_processing_charge":"Yes (via OA deal)"},{"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"oa":1,"publisher":"Wiley","intvolume":"        55","doi":"10.1002/piuz.202301690","page":"28-33","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","keyword":["General Earth and Planetary Sciences","General Environmental Science"],"publication_identifier":{"issn":["0031-9252"],"eissn":["1521-3943"]},"type":"journal_article","oa_version":"Published Version","publication":"Physik in unserer Zeit","language":[{"iso":"ger"}],"article_processing_charge":"Yes (via OA deal)","author":[{"full_name":"Karle, Volker","last_name":"Karle","orcid":"0000-0002-6963-0129","id":"D7C012AE-D7ED-11E9-95E8-1EC5E5697425","first_name":"Volker"},{"id":"37CB05FA-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-6990-7802","first_name":"Mikhail","full_name":"Lemeshko, Mikhail","last_name":"Lemeshko"}],"month":"01","has_accepted_license":"1","article_type":"original","status":"public","quality_controlled":"1","file":[{"access_level":"open_access","file_size":1155244,"file_id":"14878","content_type":"application/pdf","success":1,"file_name":"2024_PhysikZeit_Karle.pdf","date_updated":"2024-01-23T12:18:07Z","date_created":"2024-01-23T12:18:07Z","relation":"main_file","creator":"dernst","checksum":"3051dadcf9bc57da97e36b647c596ab1"}],"date_published":"2024-01-01T00:00:00Z","ddc":["530"],"abstract":[{"text":"Die Quantenrotation ist ein spannendes Phänomen, das in vielen verschiedenen Systemen auftritt, von Molekülen und Atomen bis hin zu subatomaren Teilchen wie Neutronen und Protonen. Durch den Einsatz von starken Laserpulsen ist es möglich, die mathematisch anspruchsvolle Topologie der Rotation von Molekülen aufzudecken und topologisch geschützte Zustände zu erzeugen, die unerwartetes Verhalten zeigen. Diese Entdeckungen könnten Auswirkungen auf die Molekülphysik und physikalische Chemie haben und die Entwicklung neuer Technologien ermöglichen. Die Verbindung von Quantenrotation und Topologie stellt ein aufregendes, interdisziplinäres Forschungsfeld dar und bietet neue Wege zur Kontrolle und Nutzung von quantenmechanischen Phänomenen.","lang":"ger"}],"publication_status":"published","date_created":"2024-01-22T08:19:36Z","_id":"14851","date_updated":"2024-02-15T14:29:04Z","file_date_updated":"2024-01-23T12:18:07Z","citation":{"chicago":"Karle, Volker, and Mikhail Lemeshko. “Die faszinierende Topologie rotierender Quanten.” <i>Physik in unserer Zeit</i>. Wiley, 2024. <a href=\"https://doi.org/10.1002/piuz.202301690\">https://doi.org/10.1002/piuz.202301690</a>.","ama":"Karle V, Lemeshko M. Die faszinierende Topologie rotierender Quanten. <i>Physik in unserer Zeit</i>. 2024;55(1):28-33. doi:<a href=\"https://doi.org/10.1002/piuz.202301690\">10.1002/piuz.202301690</a>","mla":"Karle, Volker, and Mikhail Lemeshko. “Die faszinierende Topologie rotierender Quanten.” <i>Physik in unserer Zeit</i>, vol. 55, no. 1, Wiley, 2024, pp. 28–33, doi:<a href=\"https://doi.org/10.1002/piuz.202301690\">10.1002/piuz.202301690</a>.","short":"V. Karle, M. Lemeshko, Physik in unserer Zeit 55 (2024) 28–33.","ista":"Karle V, Lemeshko M. 2024. Die faszinierende Topologie rotierender Quanten. Physik in unserer Zeit. 55(1), 28–33.","apa":"Karle, V., &#38; Lemeshko, M. (2024). Die faszinierende Topologie rotierender Quanten. <i>Physik in unserer Zeit</i>. Wiley. <a href=\"https://doi.org/10.1002/piuz.202301690\">https://doi.org/10.1002/piuz.202301690</a>","ieee":"V. Karle and M. Lemeshko, “Die faszinierende Topologie rotierender Quanten,” <i>Physik in unserer Zeit</i>, vol. 55, no. 1. Wiley, pp. 28–33, 2024."},"department":[{"_id":"MiLe"}],"issue":"1","year":"2024","day":"01","title":"Die faszinierende Topologie rotierender Quanten","volume":55},{"year":"2024","issue":"4","acknowledgement":"We thank the anonymous referee for the constructive feedback that helped to improve the manuscript. We thank Michael Maseda, Daniel Schaerer, Charlotte Simmonds, and Rashmi Gottumukkala for useful comments and productive discussions. We also thank the organizers and participants of the 24th MUSE Science Busy Week in Leiden. IGK acknowledges an Excellence Master Fellowship granted by the Faculty of Science of the University of Geneva. This work has received funding from the Swiss State Secretariat for Education, Research and Innovation (SERI) under contract number MB22.00072, as well as from the Swiss National Science Foundation (SNSF) through project grant number 200020_207349 and SNSF Professorship grant number 190079. The Cosmic Dawn Center (DAWN) is funded by the Danish National Research Foundation under grant number 140. This paper is based on observations collected at the European Organisation for Astronomical Research in the Southern Hemisphere under ESO programmes 094.A-0289(B), 095.A-0010(A), 096.A-0045(A), 096.A-0045(B), 094.A-0205, 095.A-0240, 096.A-0090, 097.A-0160, and 098.A-0017. We made extensive use of several open-source software packages and we are thankful to the respective authors for sharing their work: NUMPY (Harris et al. 2020), ASTROPY (Astropy Collaboration 2022), MATPLOTLIB (Hunter 2007), IPYTHON (Perez & Granger 2007), and TOPCAT (Taylor 2005).","volume":527,"title":"Linking UV spectral properties of MUSE Ly α emitters at <i>z</i> ≳ 3 to Lyman continuum escape","day":"01","external_id":{"arxiv":["2305.07044"]},"date_created":"2024-01-22T08:22:17Z","publication_status":"published","department":[{"_id":"GradSch"},{"_id":"JoMa"}],"citation":{"short":"I. Kramarenko, J. Kerutt, A. Verhamme, P.A. Oesch, L. Barrufet, J.J. Matthee, H. Kusakabe, I. Goovaerts, T.T. Thai, Monthly Notices of the Royal Astronomical Society 527 (2024) 9853–9871.","ista":"Kramarenko I, Kerutt J, Verhamme A, Oesch PA, Barrufet L, Matthee JJ, Kusakabe H, Goovaerts I, Thai TT. 2024. Linking UV spectral properties of MUSE Ly α emitters at <i>z</i> ≳ 3 to Lyman continuum escape. Monthly Notices of the Royal Astronomical Society. 527(4), 9853–9871.","apa":"Kramarenko, I., Kerutt, J., Verhamme, A., Oesch, P. A., Barrufet, L., Matthee, J. J., … Thai, T. T. (2024). Linking UV spectral properties of MUSE Ly α emitters at <i>z</i> ≳ 3 to Lyman continuum escape. <i>Monthly Notices of the Royal Astronomical Society</i>. Oxford University Press. <a href=\"https://doi.org/10.1093/mnras/stad3853\">https://doi.org/10.1093/mnras/stad3853</a>","chicago":"Kramarenko, Ivan, J Kerutt, A Verhamme, P A Oesch, L Barrufet, Jorryt J Matthee, H Kusakabe, I Goovaerts, and T T Thai. “Linking UV Spectral Properties of MUSE Ly α Emitters at <i>z</i> ≳ 3 to Lyman Continuum Escape.” <i>Monthly Notices of the Royal Astronomical Society</i>. Oxford University Press, 2024. <a href=\"https://doi.org/10.1093/mnras/stad3853\">https://doi.org/10.1093/mnras/stad3853</a>.","ama":"Kramarenko I, Kerutt J, Verhamme A, et al. Linking UV spectral properties of MUSE Ly α emitters at <i>z</i> ≳ 3 to Lyman continuum escape. <i>Monthly Notices of the Royal Astronomical Society</i>. 2024;527(4):9853-9871. doi:<a href=\"https://doi.org/10.1093/mnras/stad3853\">10.1093/mnras/stad3853</a>","mla":"Kramarenko, Ivan, et al. “Linking UV Spectral Properties of MUSE Ly α Emitters at <i>z</i> ≳ 3 to Lyman Continuum Escape.” <i>Monthly Notices of the Royal Astronomical Society</i>, vol. 527, no. 4, Oxford University Press, 2024, pp. 9853–71, doi:<a href=\"https://doi.org/10.1093/mnras/stad3853\">10.1093/mnras/stad3853</a>.","ieee":"I. Kramarenko <i>et al.</i>, “Linking UV spectral properties of MUSE Ly α emitters at <i>z</i> ≳ 3 to Lyman continuum escape,” <i>Monthly Notices of the Royal Astronomical Society</i>, vol. 527, no. 4. Oxford University Press, pp. 9853–9871, 2024."},"file_date_updated":"2024-01-23T12:30:45Z","date_updated":"2024-01-23T12:33:50Z","_id":"14852","has_accepted_license":"1","month":"02","author":[{"last_name":"Kramarenko","full_name":"Kramarenko, Ivan","first_name":"Ivan","id":"9a9394cb-3200-11ee-973b-f5ba2a8b16e4"},{"last_name":"Kerutt","full_name":"Kerutt, J","first_name":"J"},{"full_name":"Verhamme, A","last_name":"Verhamme","first_name":"A"},{"last_name":"Oesch","full_name":"Oesch, P A","first_name":"P A"},{"first_name":"L","last_name":"Barrufet","full_name":"Barrufet, L"},{"orcid":"0000-0003-2871-127X","id":"7439a258-f3c0-11ec-9501-9df22fe06720","first_name":"Jorryt J","full_name":"Matthee, Jorryt J","last_name":"Matthee"},{"first_name":"H","last_name":"Kusakabe","full_name":"Kusakabe, H"},{"first_name":"I","last_name":"Goovaerts","full_name":"Goovaerts, I"},{"full_name":"Thai, T T","last_name":"Thai","first_name":"T T"}],"article_processing_charge":"Yes (in subscription journal)","ddc":["520"],"abstract":[{"lang":"eng","text":"The physical conditions giving rise to high escape fractions of ionizing radiation (LyC fesc) in star-forming galaxies – most likely protagonists of cosmic reionization – are not yet fully understood. Using the VLT/MUSE observations of ∼1400 Ly α emitters at 2.9 &amp;lt; z &amp;lt; 6.7, we compare stacked rest-frame UV spectra of candidates for LyC leakers and non-leakers selected based on their Ly α profiles. We find that the stacks of potential LyC leakers, i.e. galaxies with narrow, symmetric Ly α profiles with small peak separation, generally show (i) strong nebular O iii]λ1666, [Si iii]λ1883, and [C iii]λ1907 +C iii]λ1909 emission, indicating a high-ionization state of the interstellar medium (ISM); (ii) high equivalent widths of He iiλ1640 (∼1 − 3 Å), suggesting the presence of hard ionizing radiation fields; (iii) Si ii*λ1533 emission, revealing substantial amounts of neutral hydrogen off the line of sight; (iv) high C ivλλ1548,1550 to [C iii]λ1907 +C iii]λ1909 ratios (C iv/C iii] ≳0.75) , signalling the presence of low column density channels in the ISM. In contrast, the stacks with broad, asymmetric Ly α profiles with large peak separation show weak nebular emission lines, low He iiλ1640 equivalent widths (≲1 Å), and low C iv/C iii] (≲0.25), implying low-ionization states and high-neutral hydrogen column densities. Our results suggest that C iv/C iii] might be sensitive to the physical conditions that govern LyC photon escape, providing a promising tool for identification of ionizing sources among star-forming galaxies in the epoch of reionization."}],"date_published":"2024-02-01T00:00:00Z","file":[{"file_id":"14879","content_type":"application/pdf","access_level":"open_access","file_size":4521738,"file_name":"2024_MNAstronomSoc_Kramarenko.pdf","date_updated":"2024-01-23T12:30:45Z","success":1,"date_created":"2024-01-23T12:30:45Z","relation":"main_file","checksum":"9d02df4035c4951cf63dee0db1e462e9","creator":"dernst"}],"quality_controlled":"1","status":"public","article_type":"original","intvolume":"       527","oa":1,"publisher":"Oxford University Press","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"language":[{"iso":"eng"}],"publication":"Monthly Notices of the Royal Astronomical Society","arxiv":1,"oa_version":"Published Version","type":"journal_article","keyword":["Space and Planetary Science","Astronomy and Astrophysics"],"publication_identifier":{"eissn":["1365-2966"],"issn":["0035-8711"]},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","doi":"10.1093/mnras/stad3853","page":"9853-9871"},{"date_created":"2024-01-28T23:01:42Z","publication_status":"epub_ahead","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2306.05151"}],"department":[{"_id":"JuFi"}],"citation":{"apa":"Davoli, E., D’Elia, L., &#38; Ingmanns, J. (2024). Stochastic homogenization of micromagnetic energies and emergence of magnetic skyrmions. <i>Journal of Nonlinear Science</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s00332-023-10005-3\">https://doi.org/10.1007/s00332-023-10005-3</a>","ista":"Davoli E, D’Elia L, Ingmanns J. 2024. Stochastic homogenization of micromagnetic energies and emergence of magnetic skyrmions. Journal of Nonlinear Science. 34(2), 30.","short":"E. Davoli, L. D’Elia, J. Ingmanns, Journal of Nonlinear Science 34 (2024).","mla":"Davoli, Elisa, et al. “Stochastic Homogenization of Micromagnetic Energies and Emergence of Magnetic Skyrmions.” <i>Journal of Nonlinear Science</i>, vol. 34, no. 2, 30, Springer Nature, 2024, doi:<a href=\"https://doi.org/10.1007/s00332-023-10005-3\">10.1007/s00332-023-10005-3</a>.","ama":"Davoli E, D’Elia L, Ingmanns J. Stochastic homogenization of micromagnetic energies and emergence of magnetic skyrmions. <i>Journal of Nonlinear Science</i>. 2024;34(2). doi:<a href=\"https://doi.org/10.1007/s00332-023-10005-3\">10.1007/s00332-023-10005-3</a>","chicago":"Davoli, Elisa, Lorenza D’Elia, and Jonas Ingmanns. “Stochastic Homogenization of Micromagnetic Energies and Emergence of Magnetic Skyrmions.” <i>Journal of Nonlinear Science</i>. Springer Nature, 2024. <a href=\"https://doi.org/10.1007/s00332-023-10005-3\">https://doi.org/10.1007/s00332-023-10005-3</a>.","ieee":"E. Davoli, L. D’Elia, and J. Ingmanns, “Stochastic homogenization of micromagnetic energies and emergence of magnetic skyrmions,” <i>Journal of Nonlinear Science</i>, vol. 34, no. 2. Springer Nature, 2024."},"project":[{"grant_number":"F6504","name":"Taming Complexity in Partial Differential Systems","_id":"fc31cba2-9c52-11eb-aca3-ff467d239cd2"}],"date_updated":"2024-02-05T08:54:44Z","_id":"14884","year":"2024","issue":"2","acknowledgement":"All authors acknowledge support of the Austrian Science Fund (FWF) through the SFB project F65. The research of E. Davoli and L. D’Elia has additionally been supported by the FWF through grants V662, Y1292, and P35359, as well as from OeAD through the WTZ grant CZ09/2023.","volume":34,"title":"Stochastic homogenization of micromagnetic energies and emergence of magnetic skyrmions","day":"23","external_id":{"arxiv":["2306.05151"]},"intvolume":"        34","publisher":"Springer Nature","oa":1,"language":[{"iso":"eng"}],"publication":"Journal of Nonlinear Science","arxiv":1,"oa_version":"Preprint","type":"journal_article","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_identifier":{"eissn":["1432-1467"],"issn":["0938-8974"]},"doi":"10.1007/s00332-023-10005-3","article_number":"30","month":"01","author":[{"full_name":"Davoli, Elisa","last_name":"Davoli","first_name":"Elisa"},{"first_name":"Lorenza","last_name":"D’Elia","full_name":"D’Elia, Lorenza"},{"id":"71523d30-15b2-11ec-abd3-f80aa909d6b0","first_name":"Jonas","full_name":"Ingmanns, Jonas","last_name":"Ingmanns"}],"scopus_import":"1","article_processing_charge":"No","abstract":[{"text":"We perform a stochastic homogenization analysis for composite materials exhibiting a random microstructure. Under the assumptions of stationarity and ergodicity, we characterize the Gamma-limit of a micromagnetic energy functional defined on magnetizations taking value in the unit sphere and including both symmetric and antisymmetric exchange contributions. This Gamma-limit corresponds to a micromagnetic energy functional with homogeneous coefficients. We provide explicit formulas for the effective magnetic properties of the composite material in terms of homogenization correctors. Additionally, the variational analysis of the two exchange energy terms is performed in the more general setting of functionals defined on manifold-valued maps with Sobolev regularity, in the case in which the target manifold is a bounded, orientable smooth surface with tubular neighborhood of uniform thickness. Eventually, we present an explicit characterization of minimizers of the effective exchange in the case of magnetic multilayers, providing quantitative evidence of Dzyaloshinskii’s predictions on the emergence of helical structures in composite ferromagnetic materials with stochastic microstructure.","lang":"eng"}],"date_published":"2024-01-23T00:00:00Z","quality_controlled":"1","status":"public","article_type":"original"},{"has_accepted_license":"1","article_number":"e2023JD040214","scopus_import":"1","article_processing_charge":"Yes (in subscription journal)","month":"01","author":[{"first_name":"Thomas","id":"3caa3f91-1f03-11ee-96ce-e0e553054d6e","orcid":"0000-0001-7640-6152","last_name":"Shaw","full_name":"Shaw, Thomas"},{"last_name":"Buri","full_name":"Buri, Pascal","first_name":"Pascal","id":"317987aa-9421-11ee-ac5a-b941b041abba"},{"last_name":"Mccarthy","full_name":"Mccarthy, Michael","first_name":"Michael","id":"22a2674a-61ce-11ee-94b5-d18813baf16f"},{"full_name":"Miles, Evan S.","last_name":"Miles","first_name":"Evan S."},{"last_name":"Pellicciotti","full_name":"Pellicciotti, Francesca","first_name":"Francesca","id":"b28f055a-81ea-11ed-b70c-a9fe7f7b0e70","orcid":"0000-0002-5554-8087"}],"file":[{"success":1,"date_updated":"2024-02-06T08:38:27Z","file_name":"2024_JGRAtmospheres_Shaw.pdf","access_level":"open_access","file_size":7481087,"file_id":"14943","content_type":"application/pdf","creator":"dernst","checksum":"cad5b93caadb40c14e5faedc34f7bba7","date_created":"2024-02-06T08:38:27Z","relation":"main_file"}],"ddc":["550"],"abstract":[{"lang":"eng","text":"The near-surface boundary layer can mediate the response of mountain glaciers to external climate, cooling the overlying air and promoting a density-driven glacier wind. The fundamental processes are conceptually well understood, though the magnitudes of cooling and presence of glacier winds are poorly quantified in space and time, increasing the forcing uncertainty for melt models. We utilize a new data set of on-glacier meteorological measurements on three neighboring glaciers in the Swiss Alps to explore their distinct response to regional climate under the extreme 2022 summer. We find that synoptic wind origins and local terrain modifications, not only glacier size, play an important role in the ability of a glacier to cool the near-surface air. Warm air intrusions from valley or synoptically-driven winds onto the glacier can occur between ∼19% and 64% of the time and contribute between 3% and 81% of the total sensible heat flux to the surface during warm afternoon hours, depending on the fetch of the glacier flowline and its susceptibility to boundary layer erosion. In the context of extreme summer warmth, indicative of future conditions, the boundary layer cooling (up to 6.5°C cooler than its surroundings) and resultant katabatic wind flow are highly heterogeneous between the study glaciers, highlighting the complex and likely non-linear response of glaciers to an uncertain future."}],"date_published":"2024-01-28T00:00:00Z","status":"public","article_type":"original","quality_controlled":"1","publisher":"Wiley","oa":1,"intvolume":"       129","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"related_material":{"record":[{"id":"14919","relation":"research_data","status":"public"}]},"language":[{"iso":"eng"}],"publication":"Journal of Geophysical Research: Atmospheres","oa_version":"Published Version","doi":"10.1029/2023JD040214","type":"journal_article","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_identifier":{"issn":["2169-897X"],"eissn":["2169-8996"]},"year":"2024","issue":"2","acknowledgement":"This project has received funding from the European Union's Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No. 101026058. The authors acknowledge the invaluable field assistance of Marta Corrà, Achille Jouberton, Marin Kneib, Stefan Fugger, Celine Ducret and Alexander Groos. The authors would also like to thank Luca Carturan for advice regarding AWS setup and maintenance and Simone Fatichi for provision and support in the use of the Tethys-Chloris model. Open access funding provided by ETH-Bereich Forschungsanstalten.","volume":129,"title":"Local controls on near-surface glacier cooling under warm atmospheric conditions","day":"28","date_created":"2024-01-28T23:01:42Z","publication_status":"published","department":[{"_id":"FrPe"}],"citation":{"short":"T. Shaw, P. Buri, M. McCarthy, E.S. Miles, F. Pellicciotti, Journal of Geophysical Research: Atmospheres 129 (2024).","ista":"Shaw T, Buri P, McCarthy M, Miles ES, Pellicciotti F. 2024. Local controls on near-surface glacier cooling under warm atmospheric conditions. Journal of Geophysical Research: Atmospheres. 129(2), e2023JD040214.","apa":"Shaw, T., Buri, P., McCarthy, M., Miles, E. S., &#38; Pellicciotti, F. (2024). Local controls on near-surface glacier cooling under warm atmospheric conditions. <i>Journal of Geophysical Research: Atmospheres</i>. Wiley. <a href=\"https://doi.org/10.1029/2023JD040214\">https://doi.org/10.1029/2023JD040214</a>","chicago":"Shaw, Thomas, Pascal Buri, Michael McCarthy, Evan S. Miles, and Francesca Pellicciotti. “Local Controls on Near-Surface Glacier Cooling under Warm Atmospheric Conditions.” <i>Journal of Geophysical Research: Atmospheres</i>. Wiley, 2024. <a href=\"https://doi.org/10.1029/2023JD040214\">https://doi.org/10.1029/2023JD040214</a>.","mla":"Shaw, Thomas, et al. “Local Controls on Near-Surface Glacier Cooling under Warm Atmospheric Conditions.” <i>Journal of Geophysical Research: Atmospheres</i>, vol. 129, no. 2, e2023JD040214, Wiley, 2024, doi:<a href=\"https://doi.org/10.1029/2023JD040214\">10.1029/2023JD040214</a>.","ama":"Shaw T, Buri P, McCarthy M, Miles ES, Pellicciotti F. Local controls on near-surface glacier cooling under warm atmospheric conditions. <i>Journal of Geophysical Research: Atmospheres</i>. 2024;129(2). doi:<a href=\"https://doi.org/10.1029/2023JD040214\">10.1029/2023JD040214</a>","ieee":"T. Shaw, P. Buri, M. McCarthy, E. S. Miles, and F. Pellicciotti, “Local controls on near-surface glacier cooling under warm atmospheric conditions,” <i>Journal of Geophysical Research: Atmospheres</i>, vol. 129, no. 2. Wiley, 2024."},"date_updated":"2024-02-06T08:44:02Z","_id":"14885","file_date_updated":"2024-02-06T08:38:27Z"},{"year":"2024","issue":"1","acknowledgement":"The work was supported by the Institute of Science and Technology Austria (ISTA). We thank Prof. John M. Dudley, Dr. Ugur Sezer, and Dr. Artem Volosniev for valuable discussions.","volume":6,"title":"Dispersive effects in ultrafast nonlinear phenomena: The case of optical Kerr effect","day":"11","date_created":"2024-01-28T23:01:42Z","publication_status":"published","department":[{"_id":"ZhAl"}],"citation":{"ieee":"D. Lorenc and Z. Alpichshev, “Dispersive effects in ultrafast nonlinear phenomena: The case of optical Kerr effect,” <i>Physical Review Research</i>, vol. 6, no. 1. American Physical Society, 2024.","ama":"Lorenc D, Alpichshev Z. Dispersive effects in ultrafast nonlinear phenomena: The case of optical Kerr effect. <i>Physical Review Research</i>. 2024;6(1). doi:<a href=\"https://doi.org/10.1103/PhysRevResearch.6.013042\">10.1103/PhysRevResearch.6.013042</a>","mla":"Lorenc, Dusan, and Zhanybek Alpichshev. “Dispersive Effects in Ultrafast Nonlinear Phenomena: The Case of Optical Kerr Effect.” <i>Physical Review Research</i>, vol. 6, no. 1, 013042, American Physical Society, 2024, doi:<a href=\"https://doi.org/10.1103/PhysRevResearch.6.013042\">10.1103/PhysRevResearch.6.013042</a>.","chicago":"Lorenc, Dusan, and Zhanybek Alpichshev. “Dispersive Effects in Ultrafast Nonlinear Phenomena: The Case of Optical Kerr Effect.” <i>Physical Review Research</i>. American Physical Society, 2024. <a href=\"https://doi.org/10.1103/PhysRevResearch.6.013042\">https://doi.org/10.1103/PhysRevResearch.6.013042</a>.","apa":"Lorenc, D., &#38; Alpichshev, Z. (2024). Dispersive effects in ultrafast nonlinear phenomena: The case of optical Kerr effect. <i>Physical Review Research</i>. American Physical Society. <a href=\"https://doi.org/10.1103/PhysRevResearch.6.013042\">https://doi.org/10.1103/PhysRevResearch.6.013042</a>","ista":"Lorenc D, Alpichshev Z. 2024. Dispersive effects in ultrafast nonlinear phenomena: The case of optical Kerr effect. Physical Review Research. 6(1), 013042.","short":"D. Lorenc, Z. Alpichshev, Physical Review Research 6 (2024)."},"date_updated":"2024-01-31T12:01:16Z","_id":"14886","file_date_updated":"2024-01-31T11:59:30Z","article_number":"013042","has_accepted_license":"1","article_processing_charge":"Yes","scopus_import":"1","month":"01","author":[{"first_name":"Dusan","id":"40D8A3E6-F248-11E8-B48F-1D18A9856A87","last_name":"Lorenc","full_name":"Lorenc, Dusan"},{"orcid":"0000-0002-7183-5203","id":"45E67A2A-F248-11E8-B48F-1D18A9856A87","first_name":"Zhanybek","full_name":"Alpichshev, Zhanybek","last_name":"Alpichshev"}],"file":[{"date_updated":"2024-01-31T11:59:30Z","file_name":"2024_PhysicalReviewResearch_Lorenc.pdf","success":1,"content_type":"application/pdf","file_id":"14918","file_size":2863627,"access_level":"open_access","checksum":"42d58f93ae74e7f2c4de058ef75ff8b2","creator":"dernst","relation":"main_file","date_created":"2024-01-31T11:59:30Z"}],"ddc":["530"],"abstract":[{"lang":"eng","text":"It is a basic principle that an effect cannot come before the cause. Dispersive relations that follow from this fundamental fact have proven to be an indispensable tool in physics and engineering. They are most powerful in the domain of linear response where they are known as Kramers-Kronig relations. However, when it comes to nonlinear phenomena the implications of causality are much less explored, apart from several notable exceptions. Here in this paper we demonstrate how to apply the dispersive formalism to analyze the ultrafast nonlinear response in the context of the paradigmatic nonlinear Kerr effect. We find that the requirement of causality introduces a noticeable effect even under assumption that Kerr effect is mediated by quasi-instantaneous off-resonant electronic hyperpolarizability. We confirm this by experimentally measuring the time-resolved Kerr dynamics in GaAs by means of a hybrid pump-probe Mach-Zehnder interferometer and demonstrate the presence of an intrinsic lagging between amplitude and phase responses as predicted by dispersive analysis. Our results describe a general property of the time-resolved nonlinear processes thereby highlighting the importance of accounting for dispersive effects in the nonlinear optical processes involving ultrashort pulses."}],"date_published":"2024-01-11T00:00:00Z","status":"public","article_type":"original","quality_controlled":"1","publisher":"American Physical Society","oa":1,"intvolume":"         6","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"language":[{"iso":"eng"}],"publication":"Physical Review Research","oa_version":"Published Version","doi":"10.1103/PhysRevResearch.6.013042","type":"journal_article","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_identifier":{"eissn":["2643-1564"]}},{"main_file_link":[{"open_access":"1","url":"https://doi.org/10.1038/s41593-023-01551-w"}],"publication_status":"epub_ahead","date_created":"2024-01-28T23:01:43Z","date_updated":"2024-01-29T09:22:00Z","_id":"14887","department":[{"_id":"TiVo"}],"citation":{"mla":"Feitosa Tomé, Douglas, et al. “Dynamic and Selective Engrams Emerge with Memory Consolidation.” <i>Nature Neuroscience</i>, Springer Nature, 2024, doi:<a href=\"https://doi.org/10.1038/s41593-023-01551-w\">10.1038/s41593-023-01551-w</a>.","ama":"Feitosa Tomé D, Zhang Y, Aida T, et al. Dynamic and selective engrams emerge with memory consolidation. <i>Nature Neuroscience</i>. 2024. doi:<a href=\"https://doi.org/10.1038/s41593-023-01551-w\">10.1038/s41593-023-01551-w</a>","chicago":"Feitosa Tomé, Douglas, Ying Zhang, Tomomi Aida, Olivia Mosto, Yifeng Lu, Mandy Chen, Sadra Sadeh, Dheeraj S. Roy, and Claudia Clopath. “Dynamic and Selective Engrams Emerge with Memory Consolidation.” <i>Nature Neuroscience</i>. Springer Nature, 2024. <a href=\"https://doi.org/10.1038/s41593-023-01551-w\">https://doi.org/10.1038/s41593-023-01551-w</a>.","apa":"Feitosa Tomé, D., Zhang, Y., Aida, T., Mosto, O., Lu, Y., Chen, M., … Clopath, C. (2024). Dynamic and selective engrams emerge with memory consolidation. <i>Nature Neuroscience</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41593-023-01551-w\">https://doi.org/10.1038/s41593-023-01551-w</a>","ista":"Feitosa Tomé D, Zhang Y, Aida T, Mosto O, Lu Y, Chen M, Sadeh S, Roy DS, Clopath C. 2024. Dynamic and selective engrams emerge with memory consolidation. Nature Neuroscience.","short":"D. Feitosa Tomé, Y. Zhang, T. Aida, O. Mosto, Y. Lu, M. Chen, S. Sadeh, D.S. Roy, C. Clopath, Nature Neuroscience (2024).","ieee":"D. Feitosa Tomé <i>et al.</i>, “Dynamic and selective engrams emerge with memory consolidation,” <i>Nature Neuroscience</i>. Springer Nature, 2024."},"year":"2024","external_id":{"isi":["001145442300001"]},"title":"Dynamic and selective engrams emerge with memory consolidation","day":"19","acknowledgement":"We thank S. Erisken from Inscopix for helping us establish in vivo one-photon calcium imaging for this work. We thank K. Su at Tsinghua University for assistance with this work. This work was funded by the President’s PhD Scholarship from Imperial College London (D.F.T.), the Wellcome Trust (225412/Z/22/Z) (S.S.), the Biotechnology and Biological Sciences Research Council (BB/N013956/1 and BB/N019008/1) (C.C.), the Wellcome Trust (200790/Z/16/Z) (C.C.), the Simons Foundation (564408) (C.C.) and the Engineering and Physical Sciences Research Council (EP/R035806/1) (CC). The School of Life Sciences and the IDG/McGovern Institute for Brain Research supported Y.Z. The Warren Alpert Distinguished Scholar Award and National Institutes of Health 1K99NS125131-01 supported D.S.R.","oa":1,"publisher":"Springer Nature","isi":1,"doi":"10.1038/s41593-023-01551-w","type":"journal_article","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_identifier":{"issn":["1097-6256"],"eissn":["1546-1726"]},"related_material":{"record":[{"status":"public","relation":"research_data","id":"14892"}]},"language":[{"iso":"eng"}],"oa_version":"Published Version","publication":"Nature Neuroscience","scopus_import":"1","article_processing_charge":"Yes (in subscription journal)","month":"01","author":[{"first_name":"Douglas","id":"0eed2d40-3d48-11ec-8d38-f789cc2e40b2","last_name":"Feitosa Tomé","full_name":"Feitosa Tomé, Douglas"},{"last_name":"Zhang","full_name":"Zhang, Ying","first_name":"Ying"},{"first_name":"Tomomi","full_name":"Aida, Tomomi","last_name":"Aida"},{"full_name":"Mosto, Olivia","last_name":"Mosto","first_name":"Olivia"},{"first_name":"Yifeng","full_name":"Lu, Yifeng","last_name":"Lu"},{"last_name":"Chen","full_name":"Chen, Mandy","first_name":"Mandy"},{"first_name":"Sadra","last_name":"Sadeh","full_name":"Sadeh, Sadra"},{"full_name":"Roy, Dheeraj S.","last_name":"Roy","first_name":"Dheeraj S."},{"full_name":"Clopath, Claudia","last_name":"Clopath","first_name":"Claudia"}],"status":"public","article_type":"original","quality_controlled":"1","abstract":[{"text":"Episodic memories are encoded by experience-activated neuronal ensembles that remain necessary and sufficient for recall. However, the temporal evolution of memory engrams after initial encoding is unclear. In this study, we employed computational and experimental approaches to examine how the neural composition and selectivity of engrams change with memory consolidation. Our spiking neural network model yielded testable predictions: memories transition from unselective to selective as neurons drop out of and drop into engrams; inhibitory activity during recall is essential for memory selectivity; and inhibitory synaptic plasticity during memory consolidation is critical for engrams to become selective. Using activity-dependent labeling, longitudinal calcium imaging and a combination of optogenetic and chemogenetic manipulations in mouse dentate gyrus, we conducted contextual fear conditioning experiments that supported our model’s predictions. Our results reveal that memory engrams are dynamic and that changes in engram composition mediated by inhibitory plasticity are crucial for the emergence of memory selectivity.","lang":"eng"}],"date_published":"2024-01-19T00:00:00Z"},{"date_created":"2024-01-28T23:01:43Z","publication_status":"published","main_file_link":[{"open_access":"1","url":"https://doi.org/10.48550/arXiv.2202.12175"}],"alternative_title":["LNCS"],"citation":{"ama":"De Nooijer P, Terziadis S, Weinberger A, et al. Removing popular faces in curve arrangements. In: <i>31st International Symposium on Graph Drawing and Network Visualization</i>. Vol 14466. Springer Nature; 2024:18-33. doi:<a href=\"https://doi.org/10.1007/978-3-031-49275-4_2\">10.1007/978-3-031-49275-4_2</a>","mla":"De Nooijer, Phoebe, et al. “Removing Popular Faces in Curve Arrangements.” <i>31st International Symposium on Graph Drawing and Network Visualization</i>, vol. 14466, Springer Nature, 2024, pp. 18–33, doi:<a href=\"https://doi.org/10.1007/978-3-031-49275-4_2\">10.1007/978-3-031-49275-4_2</a>.","chicago":"De Nooijer, Phoebe, Soeren Terziadis, Alexandra Weinberger, Zuzana Masárová, Tamara Mchedlidze, Maarten Löffler, and Günter Rote. “Removing Popular Faces in Curve Arrangements.” In <i>31st International Symposium on Graph Drawing and Network Visualization</i>, 14466:18–33. Springer Nature, 2024. <a href=\"https://doi.org/10.1007/978-3-031-49275-4_2\">https://doi.org/10.1007/978-3-031-49275-4_2</a>.","apa":"De Nooijer, P., Terziadis, S., Weinberger, A., Masárová, Z., Mchedlidze, T., Löffler, M., &#38; Rote, G. (2024). Removing popular faces in curve arrangements. In <i>31st International Symposium on Graph Drawing and Network Visualization</i> (Vol. 14466, pp. 18–33). Isola delle Femmine, Palermo, Italy: Springer Nature. <a href=\"https://doi.org/10.1007/978-3-031-49275-4_2\">https://doi.org/10.1007/978-3-031-49275-4_2</a>","ista":"De Nooijer P, Terziadis S, Weinberger A, Masárová Z, Mchedlidze T, Löffler M, Rote G. 2024. Removing popular faces in curve arrangements. 31st International Symposium on Graph Drawing and Network Visualization. GD: Graph Drawing and Network Visualization, LNCS, vol. 14466, 18–33.","short":"P. De Nooijer, S. Terziadis, A. Weinberger, Z. Masárová, T. Mchedlidze, M. Löffler, G. Rote, in:, 31st International Symposium on Graph Drawing and Network Visualization, Springer Nature, 2024, pp. 18–33.","ieee":"P. De Nooijer <i>et al.</i>, “Removing popular faces in curve arrangements,” in <i>31st International Symposium on Graph Drawing and Network Visualization</i>, Isola delle Femmine, Palermo, Italy, 2024, vol. 14466, pp. 18–33."},"department":[{"_id":"UlWa"},{"_id":"HeEd"}],"conference":{"start_date":"2023-09-20","location":"Isola delle Femmine, Palermo, Italy","name":"GD: Graph Drawing and Network Visualization","end_date":"2023-09-22"},"project":[{"grant_number":"101087907","_id":"bdb2a702-d553-11ed-ba76-f12e3e5a3bc6","name":"A quantum hybrid of atoms and milligram-scale pendulums: towards gravitational quantum mechanics"}],"_id":"14888","date_updated":"2025-07-21T07:28:03Z","year":"2024","volume":14466,"acknowledgement":"This work was initiated at the 16th European Research Week on Geometric Graphs in Strobl in 2019. A.W. is supported by the Austrian Science Fund (FWF): W1230. S.T. has been funded by the Vienna Science and Technology Fund (WWTF) [10.47379/ICT19035]. A preliminary version of this work has been presented at the 38th European Workshop on Computational Geometry (EuroCG 2022) in Perugia [9]. A full version of this paper, which includes appendices but is otherwise identical, is available as a technical report [10].","day":"06","title":"Removing popular faces in curve arrangements","external_id":{"arxiv":["2202.12175"]},"intvolume":"     14466","publisher":"Springer Nature","oa":1,"oa_version":"Preprint","arxiv":1,"publication":"31st International Symposium on Graph Drawing and Network Visualization","language":[{"iso":"eng"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_identifier":{"eissn":["1611-3349"],"isbn":["9783031492747"],"issn":["0302-9743"]},"type":"conference","page":"18-33","doi":"10.1007/978-3-031-49275-4_2","author":[{"first_name":"Phoebe","last_name":"De Nooijer","full_name":"De Nooijer, Phoebe"},{"last_name":"Terziadis","full_name":"Terziadis, Soeren","first_name":"Soeren"},{"last_name":"Weinberger","full_name":"Weinberger, Alexandra","first_name":"Alexandra"},{"full_name":"Masárová, Zuzana","last_name":"Masárová","orcid":"0000-0002-6660-1322","id":"45CFE238-F248-11E8-B48F-1D18A9856A87","first_name":"Zuzana"},{"first_name":"Tamara","last_name":"Mchedlidze","full_name":"Mchedlidze, Tamara"},{"last_name":"Löffler","full_name":"Löffler, Maarten","first_name":"Maarten"},{"first_name":"Günter","last_name":"Rote","full_name":"Rote, Günter"}],"month":"01","scopus_import":"1","article_processing_charge":"No","date_published":"2024-01-06T00:00:00Z","abstract":[{"lang":"eng","text":"A face in a curve arrangement is called popular if it is bounded by the same curve multiple times. Motivated by the automatic generation of curved nonogram puzzles, we investigate possibilities to eliminate the popular faces in an arrangement by inserting a single additional curve. This turns out to be NP-hard; however, it becomes tractable when the number of popular faces is small: We present a probabilistic FPT-approach in the number of popular faces."}],"quality_controlled":"1","status":"public"},{"has_accepted_license":"1","article_processing_charge":"Yes","scopus_import":"1","author":[{"full_name":"Nomura, Keiko","last_name":"Nomura","first_name":"Keiko"},{"last_name":"Rella","full_name":"Rella, Simon","first_name":"Simon","id":"B4765ACA-AA38-11E9-AC9A-0930E6697425"},{"last_name":"Merritt","full_name":"Merritt, Haily","first_name":"Haily"},{"last_name":"Baltussen","full_name":"Baltussen, Mathieu","first_name":"Mathieu"},{"last_name":"Bird","full_name":"Bird, Darcy","first_name":"Darcy"},{"full_name":"Tjuka, Annika","last_name":"Tjuka","first_name":"Annika"},{"full_name":"Falk, Dan","last_name":"Falk","first_name":"Dan"}],"month":"01","file":[{"creator":"dernst","checksum":"b80ebc889033c365d8f8c05a0c655382","date_created":"2024-02-05T10:06:35Z","relation":"main_file","success":1,"file_name":"2023_IntJourCommons_Nomura.pdf","date_updated":"2024-02-05T10:06:35Z","access_level":"open_access","file_size":1305786,"file_id":"14939","content_type":"application/pdf"}],"date_published":"2024-01-11T00:00:00Z","abstract":[{"text":"Global services like navigation, communication, and Earth observation have increased dramatically in the 21st century due to advances in outer space industries. But as orbits become increasingly crowded with both satellites and inevitable space debris pollution, continued operations become endangered by the heightened risks of debris collisions in orbit. Kessler Syndrome is the term for when a critical threshold of orbiting debris triggers a runaway positive feedback loop of debris collisions, creating debris congestion that can render orbits unusable. As this potential tipping point becomes more widely recognized, there have been renewed calls for debris mitigation and removal. Here, we combine complex systems and social-ecological systems approaches to study how these efforts may affect space debris accumulation and the likelihood of reaching Kessler Syndrome. Specifically, we model how debris levels are affected by future launch rates, cleanup activities, and collisions between extant debris. We contextualize and interpret our dynamic model within a discussion of existing space debris governance and other social, economic, and geopolitical factors that may influence effective collective management of the orbital commons. In line with previous studies, our model finds that debris congestion may be reached in less than 200 years, though a holistic management strategy combining removal and mitigation actions can avoid such outcomes while continuing space activities. Moreover, although active debris removal may be particularly effective, the current lack of market and governance support may impede its implementation. Research into these critical dynamics and the multi-faceted variables that influence debris outcomes can support policymakers in curating impactful governance strategies and realistic transition pathways to sustaining debris-free orbits. Overall, our study is useful for communicating about space debris sustainability in policy and education settings by providing an exploration of policy portfolio options supported by a simple and clear social-ecological modeling approach.","lang":"eng"}],"ddc":["550"],"article_type":"original","status":"public","quality_controlled":"1","oa":1,"publisher":"Ubiquity Press","intvolume":"        18","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"publication":"International Journal of the Commons","oa_version":"Published Version","language":[{"iso":"eng"}],"doi":"10.5334/ijc.1275","publication_identifier":{"issn":["1875-0281"]},"keyword":["Sociology and Political Science"],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","type":"journal_article","issue":"1","year":"2024","volume":18,"acknowledgement":"The authors would like to thank the special issue co-editors, Marco Janssen and Xiao-Shan Yap, and the anonymous reviewers for their comments that helped improve the manuscript. The paper also benefited from suggestions by other author participants in this special issue. We would also like to thank the 2022 Santa Fe Institute Complex Systems Summer School for providing space to initiate this study.","day":"11","title":"Tipping points of space debris in low earth orbit","date_created":"2024-01-30T11:58:02Z","publication_status":"published","citation":{"short":"K. Nomura, S. Rella, H. Merritt, M. Baltussen, D. Bird, A. Tjuka, D. Falk, International Journal of the Commons 18 (2024).","apa":"Nomura, K., Rella, S., Merritt, H., Baltussen, M., Bird, D., Tjuka, A., &#38; Falk, D. (2024). Tipping points of space debris in low earth orbit. <i>International Journal of the Commons</i>. Ubiquity Press. <a href=\"https://doi.org/10.5334/ijc.1275\">https://doi.org/10.5334/ijc.1275</a>","ista":"Nomura K, Rella S, Merritt H, Baltussen M, Bird D, Tjuka A, Falk D. 2024. Tipping points of space debris in low earth orbit. International Journal of the Commons. 18(1).","chicago":"Nomura, Keiko, Simon Rella, Haily Merritt, Mathieu Baltussen, Darcy Bird, Annika Tjuka, and Dan Falk. “Tipping Points of Space Debris in Low Earth Orbit.” <i>International Journal of the Commons</i>. Ubiquity Press, 2024. <a href=\"https://doi.org/10.5334/ijc.1275\">https://doi.org/10.5334/ijc.1275</a>.","mla":"Nomura, Keiko, et al. “Tipping Points of Space Debris in Low Earth Orbit.” <i>International Journal of the Commons</i>, vol. 18, no. 1, Ubiquity Press, 2024, doi:<a href=\"https://doi.org/10.5334/ijc.1275\">10.5334/ijc.1275</a>.","ama":"Nomura K, Rella S, Merritt H, et al. Tipping points of space debris in low earth orbit. <i>International Journal of the Commons</i>. 2024;18(1). doi:<a href=\"https://doi.org/10.5334/ijc.1275\">10.5334/ijc.1275</a>","ieee":"K. Nomura <i>et al.</i>, “Tipping points of space debris in low earth orbit,” <i>International Journal of the Commons</i>, vol. 18, no. 1. Ubiquity Press, 2024."},"department":[{"_id":"GradSch"},{"_id":"GaTk"}],"_id":"14901","date_updated":"2024-02-05T10:10:27Z","file_date_updated":"2024-02-05T10:06:35Z"},{"department":[{"_id":"TaHa"}],"citation":{"ieee":"T. Hausel, E. Letellier, and F. Rodriguez-Villegas, “Locally free representations of quivers over commutative Frobenius algebras,” <i>Selecta Mathematica</i>, vol. 30, no. 2. Springer Nature, 2024.","chicago":"Hausel, Tamás, Emmanuel Letellier, and Fernando Rodriguez-Villegas. “Locally Free Representations of Quivers over Commutative Frobenius Algebras.” <i>Selecta Mathematica</i>. Springer Nature, 2024. <a href=\"https://doi.org/10.1007/s00029-023-00914-2\">https://doi.org/10.1007/s00029-023-00914-2</a>.","mla":"Hausel, Tamás, et al. “Locally Free Representations of Quivers over Commutative Frobenius Algebras.” <i>Selecta Mathematica</i>, vol. 30, no. 2, 20, Springer Nature, 2024, doi:<a href=\"https://doi.org/10.1007/s00029-023-00914-2\">10.1007/s00029-023-00914-2</a>.","ama":"Hausel T, Letellier E, Rodriguez-Villegas F. Locally free representations of quivers over commutative Frobenius algebras. <i>Selecta Mathematica</i>. 2024;30(2). doi:<a href=\"https://doi.org/10.1007/s00029-023-00914-2\">10.1007/s00029-023-00914-2</a>","short":"T. Hausel, E. Letellier, F. Rodriguez-Villegas, Selecta Mathematica 30 (2024).","apa":"Hausel, T., Letellier, E., &#38; Rodriguez-Villegas, F. (2024). Locally free representations of quivers over commutative Frobenius algebras. <i>Selecta Mathematica</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s00029-023-00914-2\">https://doi.org/10.1007/s00029-023-00914-2</a>","ista":"Hausel T, Letellier E, Rodriguez-Villegas F. 2024. Locally free representations of quivers over commutative Frobenius algebras. Selecta Mathematica. 30(2), 20."},"date_updated":"2024-02-05T12:58:21Z","_id":"14930","date_created":"2024-02-04T23:00:53Z","publication_status":"epub_ahead","acknowledgement":"Special thanks go to Christof Geiss, Bernard Leclerc and Jan Schröer for explaining their work but also for sharing some unpublished results with us. We also thank the referee for many useful suggestions. We would like to thank Tommaso Scognamiglio for pointing out a mistake in the proof of Proposition 5.17 in an earlier version of the paper. We would like also to thank Alexander Beilinson, Bill Crawley-Boevey, Joel Kamnitzer, and Peng Shan for useful discussions.","volume":30,"title":"Locally free representations of quivers over commutative Frobenius algebras","day":"27","year":"2024","issue":"2","language":[{"iso":"eng"}],"publication":"Selecta Mathematica","oa_version":"None","doi":"10.1007/s00029-023-00914-2","type":"journal_article","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publication_identifier":{"issn":["1022-1824"],"eissn":["1420-9020"]},"publisher":"Springer Nature","intvolume":"        30","abstract":[{"lang":"eng","text":"In this paper we investigate locally free representations of a quiver Q over a commutative Frobenius algebra R by arithmetic Fourier transform. When the base field is finite we prove that the number of isomorphism classes of absolutely indecomposable locally free representations of fixed rank is independent of the orientation of Q. We also prove that the number of isomorphism classes of locally free absolutely indecomposable representations of the preprojective algebra of Q over R equals the number of isomorphism classes of locally free absolutely indecomposable representations of Q over R[t]/(t2). Using these results together with results of Geiss, Leclerc and Schröer we give, when k is algebraically closed, a classification of pairs (Q, R) such that the set of isomorphism classes of indecomposable locally free representations of Q over R is finite. Finally when the representation is free of rank 1 at each vertex of Q, we study the function that counts the number of isomorphism classes of absolutely indecomposable locally free representations of Q over the Frobenius algebra Fq[t]/(tr). We prove that they are polynomial in q and their generating function is rational and satisfies a functional equation."}],"date_published":"2024-01-27T00:00:00Z","status":"public","article_type":"original","quality_controlled":"1","article_number":"20","scopus_import":"1","article_processing_charge":"No","month":"01","author":[{"first_name":"Tamás","id":"4A0666D8-F248-11E8-B48F-1D18A9856A87","last_name":"Hausel","full_name":"Hausel, Tamás"},{"first_name":"Emmanuel","last_name":"Letellier","full_name":"Letellier, Emmanuel"},{"full_name":"Rodriguez-Villegas, Fernando","last_name":"Rodriguez-Villegas","first_name":"Fernando"}]},{"oa":1,"publisher":"Elsevier","intvolume":"       286","arxiv":1,"oa_version":"Published Version","publication":"Journal of Functional Analysis","language":[{"iso":"eng"}],"ec_funded":1,"doi":"10.1016/j.jfa.2024.110320","publication_identifier":{"issn":["0022-1236"],"eissn":["1096--0783"]},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","type":"journal_article","article_number":"110320","scopus_import":"1","article_processing_charge":"Yes (in subscription journal)","author":[{"full_name":"Lauritsen, Asbjørn Bækgaard","last_name":"Lauritsen","id":"e1a2682f-dc8d-11ea-abe3-81da9ac728f1","orcid":"0000-0003-4476-2288","first_name":"Asbjørn Bækgaard"},{"id":"4AFD0470-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-6781-0521","first_name":"Robert","full_name":"Seiringer, Robert","last_name":"Seiringer"}],"month":"01","date_published":"2024-01-24T00:00:00Z","abstract":[{"text":"We prove an upper bound on the ground state energy of the dilute spin-polarized Fermi gas capturing the leading correction to the kinetic energy resulting from repulsive interactions. One of the main ingredients in the proof is a rigorous implementation of the fermionic cluster expansion of Gaudin et al. (1971) [15].","lang":"eng"}],"article_type":"original","status":"public","quality_controlled":"1","date_created":"2024-02-04T23:00:53Z","publication_status":"epub_ahead","main_file_link":[{"url":"https://doi.org/10.1016/j.jfa.2024.110320","open_access":"1"}],"citation":{"chicago":"Lauritsen, Asbjørn Bækgaard, and Robert Seiringer. “Ground State Energy of the Dilute Spin-Polarized Fermi Gas: Upper Bound via Cluster Expansion.” <i>Journal of Functional Analysis</i>. Elsevier, 2024. <a href=\"https://doi.org/10.1016/j.jfa.2024.110320\">https://doi.org/10.1016/j.jfa.2024.110320</a>.","mla":"Lauritsen, Asbjørn Bækgaard, and Robert Seiringer. “Ground State Energy of the Dilute Spin-Polarized Fermi Gas: Upper Bound via Cluster Expansion.” <i>Journal of Functional Analysis</i>, vol. 286, no. 7, 110320, Elsevier, 2024, doi:<a href=\"https://doi.org/10.1016/j.jfa.2024.110320\">10.1016/j.jfa.2024.110320</a>.","ama":"Lauritsen AB, Seiringer R. Ground state energy of the dilute spin-polarized Fermi gas: Upper bound via cluster expansion. <i>Journal of Functional Analysis</i>. 2024;286(7). doi:<a href=\"https://doi.org/10.1016/j.jfa.2024.110320\">10.1016/j.jfa.2024.110320</a>","short":"A.B. Lauritsen, R. Seiringer, Journal of Functional Analysis 286 (2024).","apa":"Lauritsen, A. B., &#38; Seiringer, R. (2024). Ground state energy of the dilute spin-polarized Fermi gas: Upper bound via cluster expansion. <i>Journal of Functional Analysis</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.jfa.2024.110320\">https://doi.org/10.1016/j.jfa.2024.110320</a>","ista":"Lauritsen AB, Seiringer R. 2024. Ground state energy of the dilute spin-polarized Fermi gas: Upper bound via cluster expansion. Journal of Functional Analysis. 286(7), 110320.","ieee":"A. B. Lauritsen and R. Seiringer, “Ground state energy of the dilute spin-polarized Fermi gas: Upper bound via cluster expansion,” <i>Journal of Functional Analysis</i>, vol. 286, no. 7. Elsevier, 2024."},"department":[{"_id":"RoSe"}],"_id":"14931","date_updated":"2024-02-05T12:53:21Z","project":[{"name":"Analysis of quantum many-body systems","_id":"25C6DC12-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","grant_number":"694227"},{"grant_number":"I06427","_id":"bda63fe5-d553-11ed-ba76-a16e3d2f256b","name":"Mathematical Challenges in BCS Theory of Superconductivity"}],"issue":"7","year":"2024","volume":286,"acknowledgement":"A.B.L. would like to thank Johannes Agerskov and Jan Philip Solovej for valuable discussions. We thank Alessandro Giuliani for helpful discussions and for pointing out the reference [18]. Funding from the European Union's Horizon 2020 research and innovation programme under the ERC grant agreement No 694227 is acknowledged. Financial support by the Austrian Science Fund (FWF) through project number I 6427-N (as part of the SFB/TRR 352) is gratefully acknowledged.","external_id":{"arxiv":["2301.04894"]},"day":"24","title":"Ground state energy of the dilute spin-polarized Fermi gas: Upper bound via cluster expansion"},{"month":"01","author":[{"full_name":"Tsuboi, Masahito","last_name":"Tsuboi","first_name":"Masahito"},{"first_name":"Bjørn Tore","full_name":"Kopperud, Bjørn Tore","last_name":"Kopperud"},{"first_name":"Michael","full_name":"Matschiner, Michael","last_name":"Matschiner"},{"first_name":"Mark","full_name":"Grabowski, Mark","last_name":"Grabowski"},{"full_name":"Syrowatka, Chrsitine","last_name":"Syrowatka","id":"205ffb76-7fe7-11eb-aa17-958bd11b99ad","first_name":"Chrsitine"},{"full_name":"Pélabon, Christophe","last_name":"Pélabon","first_name":"Christophe"},{"last_name":"Hansen","full_name":"Hansen, Thomas F.","first_name":"Thomas F."}],"article_processing_charge":"Yes (via OA deal)","scopus_import":"1","year":"2024","title":"Antler allometry, the Irish elk and Gould revisited","quality_controlled":"1","day":"29","status":"public","article_type":"original","abstract":[{"lang":"eng","text":"The huge antlers of the extinct Irish elk have invited evolutionary speculation since Darwin. In the 1970s, Stephen Jay Gould presented the first extensive data on antler size in the Irish elk and combined these with comparative data from other deer to test the hypothesis that the gigantic antlers were the outcome of a positive allometry that constrained large-bodied deer to have proportionally even larger antlers. He concluded that the Irish elk had antlers as predicted for its size and interpreted this within his emerging framework of developmental constraints as an explanatory factor in evolution. Here we reanalyze antler allometry based on new morphometric data for 57 taxa of the family Cervidae. We also present a new phylogeny for the Cervidae, which we use for comparative analyses. In contrast to Gould, we find that the antlers of Irish elk were larger than predicted from the allometry within the true deer, Cervini, as analyzed by Gould, but follow the allometry across Cervidae as a whole. After dissecting the discrepancy, we reject the allometric-constraint hypothesis because, contrary to Gould, we find no similarity between static and evolutionary allometries, and because we document extensive non-allometric evolution of antler size across the Cervidae."}],"date_published":"2024-01-29T00:00:00Z","acknowledgement":"Open access funding provided by University of Oslo (incl Oslo University Hospital).\r\nWe thank Adrian Lister, Louis Tomsett, Roberto Portela Miguez and Roula Pappa (NHMUK), Brian O'Toole and Eileen Westwig (AMNH), Daniela Kalthoff (NHRM), Alexander Bibl and Zachos Frank (NHMW), Darrin Lunde and John Ososky (NMNH), Matthew Parkes and Nigel Monaghan (NMI), Elizabetta Cioppi and Luca Bellucci (IGF), and Yoshihiro Tanaka and Hiroyuki Taruno (OMNH), who helped us in obtaining the museum data, and a special thanks to Jørgen Sikkeland (NTNU NHM) for assistance in obtaining the ontogenetic data for the red deer. We thank Olja Toljagic and Kjetil L. Voje for discussions, Ayumu Tsuboi for assistance with data collection, and Jean-Michel Gaillard and the anonymous reviewers for comments on the manuscript. We thank the Centre of Advanced Study (CAS) at the Norwegian Academy of Sciences and Letters for hosting us during the academic year of 2019/2020 when much of the analysis and writing were done. MT was funded by JSPS Research Fellowship for Young Scientists (201603238).","main_file_link":[{"url":"https://doi.org/10.1007/s11692-023-09624-1","open_access":"1"}],"publication_status":"epub_ahead","date_created":"2024-02-04T23:00:53Z","oa":1,"publisher":"Springer Nature","type":"journal_article","publication_identifier":{"issn":["0071-3260"],"eissn":["1934-2845"]},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_updated":"2024-02-05T12:43:58Z","_id":"14932","doi":"10.1007/s11692-023-09624-1","department":[{"_id":"MaRo"}],"language":[{"iso":"eng"}],"citation":{"ista":"Tsuboi M, Kopperud BT, Matschiner M, Grabowski M, Syrowatka C, Pélabon C, Hansen TF. 2024. Antler allometry, the Irish elk and Gould revisited. Evolutionary Biology.","apa":"Tsuboi, M., Kopperud, B. T., Matschiner, M., Grabowski, M., Syrowatka, C., Pélabon, C., &#38; Hansen, T. F. (2024). Antler allometry, the Irish elk and Gould revisited. <i>Evolutionary Biology</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s11692-023-09624-1\">https://doi.org/10.1007/s11692-023-09624-1</a>","short":"M. Tsuboi, B.T. Kopperud, M. Matschiner, M. Grabowski, C. Syrowatka, C. Pélabon, T.F. Hansen, Evolutionary Biology (2024).","ama":"Tsuboi M, Kopperud BT, Matschiner M, et al. Antler allometry, the Irish elk and Gould revisited. <i>Evolutionary Biology</i>. 2024. doi:<a href=\"https://doi.org/10.1007/s11692-023-09624-1\">10.1007/s11692-023-09624-1</a>","mla":"Tsuboi, Masahito, et al. “Antler Allometry, the Irish Elk and Gould Revisited.” <i>Evolutionary Biology</i>, Springer Nature, 2024, doi:<a href=\"https://doi.org/10.1007/s11692-023-09624-1\">10.1007/s11692-023-09624-1</a>.","chicago":"Tsuboi, Masahito, Bjørn Tore Kopperud, Michael Matschiner, Mark Grabowski, Chrsitine Syrowatka, Christophe Pélabon, and Thomas F. Hansen. “Antler Allometry, the Irish Elk and Gould Revisited.” <i>Evolutionary Biology</i>. Springer Nature, 2024. <a href=\"https://doi.org/10.1007/s11692-023-09624-1\">https://doi.org/10.1007/s11692-023-09624-1</a>.","ieee":"M. Tsuboi <i>et al.</i>, “Antler allometry, the Irish elk and Gould revisited,” <i>Evolutionary Biology</i>. Springer Nature, 2024."},"oa_version":"Published Version","publication":"Evolutionary Biology"},{"file_date_updated":"2024-02-05T12:35:03Z","_id":"14933","date_updated":"2024-02-05T12:37:07Z","citation":{"ieee":"A. Pimenta-Marques <i>et al.</i>, “Ana1/CEP295 is an essential player in the centrosome maintenance program regulated by Polo kinase and the PCM,” <i>EMBO reports</i>, vol. 25, no. 1. Embo Press, pp. 102–127, 2024.","chicago":"Pimenta-Marques, Ana, Tania Perestrelo, Patricia Dos Reis Rodrigues, Paulo Duarte, Ana Ferreira-Silva, Mariana Lince-Faria, and Mónica Bettencourt-Dias. “Ana1/CEP295 Is an Essential Player in the Centrosome Maintenance Program Regulated by Polo Kinase and the PCM.” <i>EMBO Reports</i>. Embo Press, 2024. <a href=\"https://doi.org/10.1038/s44319-023-00020-6\">https://doi.org/10.1038/s44319-023-00020-6</a>.","mla":"Pimenta-Marques, Ana, et al. “Ana1/CEP295 Is an Essential Player in the Centrosome Maintenance Program Regulated by Polo Kinase and the PCM.” <i>EMBO Reports</i>, vol. 25, no. 1, Embo Press, 2024, pp. 102–27, doi:<a href=\"https://doi.org/10.1038/s44319-023-00020-6\">10.1038/s44319-023-00020-6</a>.","ama":"Pimenta-Marques A, Perestrelo T, Dos Reis Rodrigues P, et al. Ana1/CEP295 is an essential player in the centrosome maintenance program regulated by Polo kinase and the PCM. <i>EMBO reports</i>. 2024;25(1):102-127. doi:<a href=\"https://doi.org/10.1038/s44319-023-00020-6\">10.1038/s44319-023-00020-6</a>","short":"A. Pimenta-Marques, T. Perestrelo, P. Dos Reis Rodrigues, P. Duarte, A. Ferreira-Silva, M. Lince-Faria, M. Bettencourt-Dias, EMBO Reports 25 (2024) 102–127.","ista":"Pimenta-Marques A, Perestrelo T, Dos Reis Rodrigues P, Duarte P, Ferreira-Silva A, Lince-Faria M, Bettencourt-Dias M. 2024. Ana1/CEP295 is an essential player in the centrosome maintenance program regulated by Polo kinase and the PCM. EMBO reports. 25(1), 102–127.","apa":"Pimenta-Marques, A., Perestrelo, T., Dos Reis Rodrigues, P., Duarte, P., Ferreira-Silva, A., Lince-Faria, M., &#38; Bettencourt-Dias, M. (2024). Ana1/CEP295 is an essential player in the centrosome maintenance program regulated by Polo kinase and the PCM. <i>EMBO Reports</i>. Embo Press. <a href=\"https://doi.org/10.1038/s44319-023-00020-6\">https://doi.org/10.1038/s44319-023-00020-6</a>"},"department":[{"_id":"MiSi"}],"publication_status":"published","date_created":"2024-02-04T23:00:53Z","day":"10","title":"Ana1/CEP295 is an essential player in the centrosome maintenance program regulated by Polo kinase and the PCM","volume":25,"acknowledgement":"We thank all members of the Cell Cycle and Regulation Lab for the discussions and for the critical reading of the manuscript. We thank Tomer Avidor-Reiss (University of Toledo, Toledo, OH), Daniel St. Johnston (The Gurdon Institute, Cambridge, UK), David Glover (University of Cambridge, Cambridge, UK), Jingyan Fu (Agricultural University, Beijing, China) Jordan Raff (University of Oxford, Oxford, UK) and Timothy Megraw (Florida State University, Tallahassee, FL) for sharing tools. We acknowledge the technical support of Instituto Gulbenkian de Ciência (IGC)‘s Advanced Imaging Facility, in particular Gabriel Martins, Nuno Pimpão Martins and José Marques. We also thank Tiago Paixão from the IGC’s Quantitative & Digital Science Unit and Marco Louro from the CCR lab for the support provided on statistical analysis. IGC’s Advanced Imaging Facility (AIF-UIC) is supported by the national Portuguese funding ref# PPBI-POCI-01-0145-FEDER -022122. We thank the IGC’s Fly Facility, supported by CONGENTO (LISBOA-01-0145-FEDER-022170). This work was supported by an ERC grant (ERC-2015-CoG-683258) awarded to MBD and a grant from the Portuguese Research Council (FCT) awarded to APM (PTDC/BIA-BID/32225/2017).","issue":"1","year":"2024","publication_identifier":{"eissn":["1469-3178"]},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","type":"journal_article","page":"102-127","doi":"10.1038/s44319-023-00020-6","publication":"EMBO reports","oa_version":"Published Version","language":[{"iso":"eng"}],"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"intvolume":"        25","oa":1,"publisher":"Embo Press","quality_controlled":"1","article_type":"original","status":"public","date_published":"2024-01-10T00:00:00Z","abstract":[{"lang":"eng","text":"Centrioles are part of centrosomes and cilia, which are microtubule organising centres (MTOC) with diverse functions. Despite their stability, centrioles can disappear during differentiation, such as in oocytes, but little is known about the regulation of their structural integrity. Our previous research revealed that the pericentriolar material (PCM) that surrounds centrioles and its recruiter, Polo kinase, are downregulated in oogenesis and sufficient for maintaining both centrosome structural integrity and MTOC activity. We now show that the expression of specific components of the centriole cartwheel and wall, including ANA1/CEP295, is essential for maintaining centrosome integrity. We find that Polo kinase requires ANA1 to promote centriole stability in cultured cells and eggs. In addition, ANA1 expression prevents the loss of centrioles observed upon PCM-downregulation. However, the centrioles maintained by overexpressing and tethering ANA1 are inactive, unlike the MTOCs observed upon tethering Polo kinase. These findings demonstrate that several centriole components are needed to maintain centrosome structure. Our study also highlights that centrioles are more dynamic than previously believed, with their structural stability relying on the continuous expression of multiple components."}],"ddc":["570"],"file":[{"checksum":"53c3ef43d9bd6d7bff3ffcf57d763cac","creator":"dernst","relation":"main_file","date_created":"2024-02-05T12:35:03Z","file_name":"2023_EmboReports_PimentaMarques.pdf","date_updated":"2024-02-05T12:35:03Z","success":1,"content_type":"application/pdf","file_id":"14941","file_size":9645056,"access_level":"open_access"}],"author":[{"full_name":"Pimenta-Marques, Ana","last_name":"Pimenta-Marques","first_name":"Ana"},{"last_name":"Perestrelo","full_name":"Perestrelo, Tania","first_name":"Tania"},{"last_name":"Dos Reis Rodrigues","full_name":"Dos Reis Rodrigues, Patricia","first_name":"Patricia","id":"26E95904-5160-11E9-9C0B-C5B0DC97E90F","orcid":"0000-0003-1681-508X"},{"full_name":"Duarte, Paulo","last_name":"Duarte","first_name":"Paulo"},{"full_name":"Ferreira-Silva, Ana","last_name":"Ferreira-Silva","first_name":"Ana"},{"first_name":"Mariana","full_name":"Lince-Faria, Mariana","last_name":"Lince-Faria"},{"first_name":"Mónica","last_name":"Bettencourt-Dias","full_name":"Bettencourt-Dias, Mónica"}],"month":"01","article_processing_charge":"Yes (in subscription journal)","scopus_import":"1","has_accepted_license":"1"},{"year":"2024","month":"01","author":[{"orcid":"0000-0002-9881-6870","id":"ECEBF480-9E4F-11EA-B557-B0823DDC885E","first_name":"Lorenzo","full_name":"Dello Schiavo, Lorenzo","last_name":"Dello Schiavo"},{"first_name":"Eva","last_name":"Kopfer","full_name":"Kopfer, Eva"},{"full_name":"Sturm, Karl Theodor","last_name":"Sturm","first_name":"Karl Theodor"}],"scopus_import":"1","article_processing_charge":"Yes (via OA deal)","abstract":[{"lang":"eng","text":"We study random perturbations of a Riemannian manifold (M, g) by means of so-called\r\nFractional Gaussian Fields, which are defined intrinsically by the given manifold. The fields\r\nh• : ω \u0002→ hω will act on the manifold via the conformal transformation g \u0002→ gω := e2hω g.\r\nOur focus will be on the regular case with Hurst parameter H > 0, the critical case H = 0\r\nbeing the celebrated Liouville geometry in two dimensions. We want to understand how basic\r\ngeometric and functional-analytic quantities like diameter, volume, heat kernel, Brownian\r\nmotion, spectral bound, or spectral gap change under the influence of the noise. And if so, is\r\nit possible to quantify these dependencies in terms of key parameters of the noise? Another\r\ngoal is to define and analyze in detail the Fractional Gaussian Fields on a general Riemannian\r\nmanifold, a fascinating object of independent interest."}],"date_published":"2024-01-26T00:00:00Z","acknowledgement":"The authors would like to thank Matthias Erbar and Ronan Herry for valuable discussions on this project. They are also grateful to Nathanaël Berestycki, and Fabrice Baudoin for respectively pointing out the references [7], and [6, 24], and to Julien Fageot and Thomas Letendre for pointing out a mistake in a previous version of the proof of Proposition 3.10. The authors feel very much indebted to an anonymous reviewer for his/her careful reading and the many valuable suggestions that have significantly contributed to the improvement of the paper. L.D.S. gratefully acknowledges financial support by the Deutsche Forschungsgemeinschaft through CRC 1060 as well as through SPP 2265, and by the Austrian Science Fund (FWF) grant F65 at Institute of Science and Technology Austria. This research was funded in whole or in part by the Austrian Science Fund (FWF) ESPRIT 208. For the purpose of open access, the authors have applied a CC BY public copyright licence to any Author Accepted Manuscript version arising from this submission. E.K. and K.-T.S. gratefully acknowledge funding by the Deutsche Forschungsgemeinschaft through the Hausdorff Center for Mathematics and through CRC 1060 as well as through SPP 2265.\r\nOpen Access funding enabled and organized by Projekt DEAL.","title":"A discovery tour in random Riemannian geometry","day":"26","quality_controlled":"1","status":"public","article_type":"original","oa":1,"publisher":"Springer Nature","date_created":"2024-02-04T23:00:54Z","main_file_link":[{"url":"https://doi.org/10.1007/s11118-023-10118-0","open_access":"1"}],"publication_status":"epub_ahead","department":[{"_id":"JaMa"}],"language":[{"iso":"eng"}],"oa_version":"Published Version","citation":{"chicago":"Dello Schiavo, Lorenzo, Eva Kopfer, and Karl Theodor Sturm. “A Discovery Tour in Random Riemannian Geometry.” <i>Potential Analysis</i>. Springer Nature, 2024. <a href=\"https://doi.org/10.1007/s11118-023-10118-0\">https://doi.org/10.1007/s11118-023-10118-0</a>.","ama":"Dello Schiavo L, Kopfer E, Sturm KT. A discovery tour in random Riemannian geometry. <i>Potential Analysis</i>. 2024. doi:<a href=\"https://doi.org/10.1007/s11118-023-10118-0\">10.1007/s11118-023-10118-0</a>","mla":"Dello Schiavo, Lorenzo, et al. “A Discovery Tour in Random Riemannian Geometry.” <i>Potential Analysis</i>, Springer Nature, 2024, doi:<a href=\"https://doi.org/10.1007/s11118-023-10118-0\">10.1007/s11118-023-10118-0</a>.","short":"L. Dello Schiavo, E. Kopfer, K.T. Sturm, Potential Analysis (2024).","ista":"Dello Schiavo L, Kopfer E, Sturm KT. 2024. A discovery tour in random Riemannian geometry. Potential Analysis.","apa":"Dello Schiavo, L., Kopfer, E., &#38; Sturm, K. T. (2024). A discovery tour in random Riemannian geometry. <i>Potential Analysis</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s11118-023-10118-0\">https://doi.org/10.1007/s11118-023-10118-0</a>","ieee":"L. Dello Schiavo, E. Kopfer, and K. T. Sturm, “A discovery tour in random Riemannian geometry,” <i>Potential Analysis</i>. Springer Nature, 2024."},"publication":"Potential Analysis","type":"journal_article","project":[{"grant_number":"F6504","_id":"fc31cba2-9c52-11eb-aca3-ff467d239cd2","name":"Taming Complexity in Partial Differential Systems"}],"publication_identifier":{"issn":["0926-2601"],"eissn":["1572-929X"]},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_updated":"2024-02-05T13:04:23Z","doi":"10.1007/s11118-023-10118-0","_id":"14934"},{"publication_status":"accepted","main_file_link":[{"url":"https://doi.org/10.1088/1748-9326/ad25a0","open_access":"1"}],"date_created":"2024-02-05T09:01:11Z","_id":"14938","date_updated":"2024-02-06T08:35:39Z","citation":{"short":"S. Fugger, T. Shaw, A. Jouberton, E. Miles, P. Buri, M. McCarthy, C.L. Fyffe, S. Fatichi, M. Kneib, P. Molnar, F. Pellicciotti, Environmental Research Letters (n.d.).","ista":"Fugger S, Shaw T, Jouberton A, Miles E, Buri P, McCarthy M, Fyffe CL, Fatichi S, Kneib M, Molnar P, Pellicciotti F. Hydrological regimes and evaporative flux partitioning at the climatic ends of High Mountain Asia. Environmental Research Letters.","apa":"Fugger, S., Shaw, T., Jouberton, A., Miles, E., Buri, P., McCarthy, M., … Pellicciotti, F. (n.d.). Hydrological regimes and evaporative flux partitioning at the climatic ends of High Mountain Asia. <i>Environmental Research Letters</i>. IOP Publishing. <a href=\"https://doi.org/10.1088/1748-9326/ad25a0\">https://doi.org/10.1088/1748-9326/ad25a0</a>","chicago":"Fugger, Stefan, Thomas Shaw, Achille Jouberton, Evan Miles, Pascal Buri, Michael McCarthy, Catriona Louise Fyffe, et al. “Hydrological Regimes and Evaporative Flux Partitioning at the Climatic Ends of High Mountain Asia.” <i>Environmental Research Letters</i>. IOP Publishing, n.d. <a href=\"https://doi.org/10.1088/1748-9326/ad25a0\">https://doi.org/10.1088/1748-9326/ad25a0</a>.","ama":"Fugger S, Shaw T, Jouberton A, et al. Hydrological regimes and evaporative flux partitioning at the climatic ends of High Mountain Asia. <i>Environmental Research Letters</i>. doi:<a href=\"https://doi.org/10.1088/1748-9326/ad25a0\">10.1088/1748-9326/ad25a0</a>","mla":"Fugger, Stefan, et al. “Hydrological Regimes and Evaporative Flux Partitioning at the Climatic Ends of High Mountain Asia.” <i>Environmental Research Letters</i>, IOP Publishing, doi:<a href=\"https://doi.org/10.1088/1748-9326/ad25a0\">10.1088/1748-9326/ad25a0</a>.","ieee":"S. Fugger <i>et al.</i>, “Hydrological regimes and evaporative flux partitioning at the climatic ends of High Mountain Asia,” <i>Environmental Research Letters</i>. IOP Publishing."},"department":[{"_id":"FrPe"}],"year":"2024","day":"02","title":"Hydrological regimes and evaporative flux partitioning at the climatic ends of High Mountain Asia","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"oa":1,"publisher":"IOP Publishing","doi":"10.1088/1748-9326/ad25a0","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","keyword":["Public Health","Environmental and Occupational Health","General Environmental Science","Renewable Energy","Sustainability and the Environment"],"publication_identifier":{"issn":["1748-9326"]},"type":"journal_article","publication":"Environmental Research Letters","oa_version":"Published Version","language":[{"iso":"eng"}],"article_processing_charge":"Yes","author":[{"full_name":"Fugger, Stefan","last_name":"Fugger","id":"86698d64-c4c6-11ee-af02-cdf1e6a7d31f","first_name":"Stefan"},{"first_name":"Thomas","id":"3caa3f91-1f03-11ee-96ce-e0e553054d6e","orcid":"0000-0001-7640-6152","last_name":"Shaw","full_name":"Shaw, Thomas"},{"first_name":"Achille","last_name":"Jouberton","full_name":"Jouberton, Achille"},{"full_name":"Miles, Evan","last_name":"Miles","first_name":"Evan"},{"id":"317987aa-9421-11ee-ac5a-b941b041abba","first_name":"Pascal","full_name":"Buri, Pascal","last_name":"Buri"},{"full_name":"McCarthy, Michael","last_name":"McCarthy","id":"22a2674a-61ce-11ee-94b5-d18813baf16f","first_name":"Michael"},{"full_name":"Fyffe, Catriona Louise","last_name":"Fyffe","id":"001b0422-8d15-11ed-bc51-cab6c037a228","first_name":"Catriona Louise"},{"first_name":"Simone","full_name":"Fatichi, Simone","last_name":"Fatichi"},{"first_name":"Marin","full_name":"Kneib, Marin","last_name":"Kneib"},{"full_name":"Molnar, Peter","last_name":"Molnar","first_name":"Peter"},{"full_name":"Pellicciotti, Francesca","last_name":"Pellicciotti","id":"b28f055a-81ea-11ed-b70c-a9fe7f7b0e70","orcid":"0000-0002-5554-8087","first_name":"Francesca"}],"month":"02","has_accepted_license":"1","article_type":"original","status":"public","quality_controlled":"1","date_published":"2024-02-02T00:00:00Z","abstract":[{"text":"High elevation headwater catchments are complex hydrological systems that seasonally buffer water and release it in the form of snow and ice melt, modulating downstream runoff regimes and water availability. In High Mountain Asia (HMA), where a wide range of climates from semi-arid to monsoonal exist, the importance of the cryospheric contributions to the water budget varies with the amount and seasonal distribution of precipitation. Losses due to evapotranspiration and sublimation are to date largely unquantified components of the water budget in such catchments, although they can be comparable in magnitude to glacier melt contributions to streamflow. &amp;#xD;Here, we simulate the hydrology of three high elevation headwater catchments in distinct climates in HMA over 10 years using an ecohydrological model geared towards high-mountain areas including snow and glaciers, forced with reanalysis data. &amp;#xD;Our results show that evapotranspiration and sublimation together are most important at the semi-arid site, Kyzylsu, on the northernmost slopes of the Pamir mountain range. Here, the evaporative loss amounts to 28% of the water throughput, which we define as the total water added to, or removed from the water balance within a year. In comparison, evaporative losses are 19% at the Central Himalayan site Langtang and 13% at the wettest site, 24K, on the Southeastern Tibetan Plateau. At the three sites, respectively, sublimation removes 15%, 13% and 6% of snowfall, while evapotranspiration removes the equivalent of 76%, 28% and 19% of rainfall. In absolute terms, and across a comparable elevation range, the highest ET flux is 413 mm yr-1 at 24K, while the highest sublimation flux is 91 mm yr-1 at Kyzylsu. During warm and dry years, glacier melt was found to only partially compensate for the annual supply deficit.","lang":"eng"}],"ddc":["550"]},{"year":"2024","acknowledgement":"We thank A. Bergthaler (Research Center for Molecular Medicine of the Austrian Academy of Sciences) for providing VACV WR. We thank A. Nicholas and his team at the ISTA proteomics facility, and S. Elefante at the ISTA Scientific Computing facility for their support. We also thank F. Fäßler, D. Porley, T. Muthspiel and other members of the Schur group for support and helpful discussions. We also thank D. Castaño-Díez for support with Dynamo. We thank D. Farrell for his help optimizing the Rosetta protocol to refine the atomic model into the cryo-EM map with symmetry.\r\n\r\nF.K.M.S. acknowledges support from ISTA and EMBO. F.K.M.S. also received support from the Austrian Science Fund (FWF) grant P31445. This publication has been made possible in part by CZI grant DAF2021-234754 and grant https://doi.org/10.37921/812628ebpcwg from the Chan Zuckerberg Initiative DAF, an advised fund of Silicon Valley Community Foundation (funder https://doi.org/10.13039/100014989) awarded to F.K.M.S.\r\n\r\nThis research was also supported by the Scientific Service Units (SSUs) of ISTA through resources provided by Scientific Computing (SciComp), the Life Science Facility (LSF), and the Electron Microscopy Facility (EMF). We also acknowledge the use of COSMIC45 and Colabfold46.","external_id":{"pmid":["38316877"]},"day":"05","title":"Multi-modal cryo-EM reveals trimers of protein A10 to form the palisade layer in poxvirus cores","date_created":"2024-02-12T09:59:45Z","pmid":1,"main_file_link":[{"open_access":"1","url":"https://doi.org/10.1038/s41594-023-01201-6"}],"publication_status":"epub_ahead","citation":{"ieee":"J. Datler <i>et al.</i>, “Multi-modal cryo-EM reveals trimers of protein A10 to form the palisade layer in poxvirus cores,” <i>Nature Structural &#38; Molecular Biology</i>. Springer Nature, 2024.","chicago":"Datler, Julia, Jesse Hansen, Andreas Thader, Alois Schlögl, Lukas W Bauer, Victor-Valentin Hodirnau, and Florian KM Schur. “Multi-Modal Cryo-EM Reveals Trimers of Protein A10 to Form the Palisade Layer in Poxvirus Cores.” <i>Nature Structural &#38; Molecular Biology</i>. Springer Nature, 2024. <a href=\"https://doi.org/10.1038/s41594-023-01201-6\">https://doi.org/10.1038/s41594-023-01201-6</a>.","mla":"Datler, Julia, et al. “Multi-Modal Cryo-EM Reveals Trimers of Protein A10 to Form the Palisade Layer in Poxvirus Cores.” <i>Nature Structural &#38; Molecular Biology</i>, Springer Nature, 2024, doi:<a href=\"https://doi.org/10.1038/s41594-023-01201-6\">10.1038/s41594-023-01201-6</a>.","ama":"Datler J, Hansen J, Thader A, et al. Multi-modal cryo-EM reveals trimers of protein A10 to form the palisade layer in poxvirus cores. <i>Nature Structural &#38; Molecular Biology</i>. 2024. doi:<a href=\"https://doi.org/10.1038/s41594-023-01201-6\">10.1038/s41594-023-01201-6</a>","short":"J. Datler, J. Hansen, A. Thader, A. Schlögl, L.W. Bauer, V.-V. Hodirnau, F.K. Schur, Nature Structural &#38; Molecular Biology (2024).","ista":"Datler J, Hansen J, Thader A, Schlögl A, Bauer LW, Hodirnau V-V, Schur FK. 2024. Multi-modal cryo-EM reveals trimers of protein A10 to form the palisade layer in poxvirus cores. Nature Structural &#38; Molecular Biology.","apa":"Datler, J., Hansen, J., Thader, A., Schlögl, A., Bauer, L. W., Hodirnau, V.-V., &#38; Schur, F. K. (2024). Multi-modal cryo-EM reveals trimers of protein A10 to form the palisade layer in poxvirus cores. <i>Nature Structural &#38; Molecular Biology</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41594-023-01201-6\">https://doi.org/10.1038/s41594-023-01201-6</a>"},"department":[{"_id":"FlSc"},{"_id":"ScienComp"},{"_id":"EM-Fac"}],"_id":"14979","date_updated":"2024-03-05T09:27:47Z","project":[{"name":"Structural conservation and diversity in retroviral capsid","call_identifier":"FWF","_id":"26736D6A-B435-11E9-9278-68D0E5697425","grant_number":"P31445"}],"has_accepted_license":"1","article_processing_charge":"Yes (in subscription journal)","author":[{"full_name":"Datler, Julia","last_name":"Datler","orcid":"0000-0002-3616-8580","id":"3B12E2E6-F248-11E8-B48F-1D18A9856A87","first_name":"Julia"},{"full_name":"Hansen, Jesse","last_name":"Hansen","id":"1063c618-6f9b-11ec-9123-f912fccded63","first_name":"Jesse"},{"first_name":"Andreas","id":"3A18A7B8-F248-11E8-B48F-1D18A9856A87","last_name":"Thader","full_name":"Thader, Andreas"},{"full_name":"Schlögl, Alois","last_name":"Schlögl","orcid":"0000-0002-5621-8100","id":"45BF87EE-F248-11E8-B48F-1D18A9856A87","first_name":"Alois"},{"last_name":"Bauer","full_name":"Bauer, Lukas W","first_name":"Lukas W","id":"0c894dcf-897b-11ed-a09c-8186353224b0"},{"first_name":"Victor-Valentin","id":"3661B498-F248-11E8-B48F-1D18A9856A87","last_name":"Hodirnau","full_name":"Hodirnau, Victor-Valentin"},{"full_name":"Schur, Florian KM","last_name":"Schur","orcid":"0000-0003-4790-8078","id":"48AD8942-F248-11E8-B48F-1D18A9856A87","first_name":"Florian KM"}],"month":"02","date_published":"2024-02-05T00:00:00Z","abstract":[{"lang":"eng","text":"Poxviruses are among the largest double-stranded DNA viruses, with members such as variola virus, monkeypox virus and the vaccination strain vaccinia virus (VACV). Knowledge about the structural proteins that form the viral core has remained sparse. While major core proteins have been annotated via indirect experimental evidence, their structures have remained elusive and they could not be assigned to individual core features. Hence, which proteins constitute which layers of the core, such as the palisade layer and the inner core wall, has remained enigmatic. Here we show, using a multi-modal cryo-electron microscopy (cryo-EM) approach in combination with AlphaFold molecular modeling, that trimers formed by the cleavage product of VACV protein A10 are the key component of the palisade layer. This allows us to place previously obtained descriptions of protein interactions within the core wall into perspective and to provide a detailed model of poxvirus core architecture. Importantly, we show that interactions within A10 trimers are likely generalizable over members of orthopox- and parapoxviruses."}],"ddc":["570"],"article_type":"original","status":"public","quality_controlled":"1","publisher":"Springer Nature","oa":1,"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"related_material":{"link":[{"url":"https://ista.ac.at/en/news/down-to-the-core-of-poxviruses/","description":"News on ISTA Website","relation":"press_release"}]},"oa_version":"Published Version","publication":"Nature Structural & Molecular Biology","language":[{"iso":"eng"}],"doi":"10.1038/s41594-023-01201-6","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","acknowledged_ssus":[{"_id":"ScienComp"},{"_id":"LifeSc"},{"_id":"EM-Fac"}],"publication_identifier":{"eissn":["1545-9985"],"issn":["1545-9993"]},"keyword":["Molecular Biology","Structural Biology"],"type":"journal_article"},{"has_accepted_license":"1","article_number":"013141","article_processing_charge":"Yes","author":[{"full_name":"Agafonova, Sofya","last_name":"Agafonova","orcid":"0000-0003-0582-2946","id":"09501ff6-dca7-11ea-a8ae-b3e0b9166e80","first_name":"Sofya"},{"last_name":"Mishra","full_name":"Mishra, Umang","first_name":"Umang","id":"4328fa4c-f128-11eb-9611-c107b0fe4d51"},{"first_name":"Fritz R","id":"2E054C4C-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-4947-8924","last_name":"Diorico","full_name":"Diorico, Fritz R"},{"first_name":"Onur","orcid":"0000-0002-2031-204X","id":"4C02D85E-F248-11E8-B48F-1D18A9856A87","last_name":"Hosten","full_name":"Hosten, Onur"}],"month":"02","file":[{"success":1,"file_name":"2024_PhysicalRevResearch_Agafonova.pdf","date_updated":"2024-02-12T11:46:50Z","access_level":"open_access","file_size":1437167,"file_id":"14981","content_type":"application/pdf","creator":"dernst","checksum":"3a39ebffb24c1cc1dd0b547a726dc52d","date_created":"2024-02-12T11:46:50Z","relation":"main_file"}],"date_published":"2024-02-05T00:00:00Z","ddc":["530"],"abstract":[{"lang":"eng","text":"Precision sensing and manipulation of milligram-scale mechanical oscillators has attracted growing interest in the fields of table-top explorations of gravity and tests of quantum mechanics at macroscopic scales. Torsional oscillators present an opportunity in this regard due to their remarked isolation from environmental noise. For torsional motion, an effective employment of optical cavities to enhance optomechanical interactions—as already established for linear oscillators—so far faced certain challenges. Here, we propose a concept for sensing and manipulating torsional motion, where exclusively the torsional rotations of a pendulum are mapped onto the path length of a single two-mirror optical cavity. The concept inherently alleviates many limitations of previous approaches. A proof-of-principle experiment is conducted with a rigidly controlled pendulum to explore the sensing aspects of the concept and to identify practical limitations in a potential state-of-the art setup. Based on this study, we anticipate development of precision torque sensors utilizing torsional pendulums that can support sensitivities below 10−19Nm/√Hz, while the motion of the pendulums are dominated by quantum radiation pressure noise at sub-microwatts of incoming laser power. These developments will provide horizons for experiments at the interface of quantum mechanics and gravity."}],"article_type":"original","status":"public","quality_controlled":"1","publisher":"American Physical Society","oa":1,"intvolume":"         6","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","image":"/images/cc_by.png"},"publication":"Physical Review Research","oa_version":"Published Version","arxiv":1,"language":[{"iso":"eng"}],"doi":"10.1103/physrevresearch.6.013141","publication_identifier":{"eissn":["2643-1564"]},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","type":"journal_article","issue":"1","year":"2024","volume":6,"acknowledgement":"We thank Pere Rosselló for his contributions to the initial modeling of the presented sensing technique. This work was supported by Institute of Science and Technology Austria, and\r\nthe European Research Council under Grant No. 101087907 (ERC CoG QuHAMP).","external_id":{"arxiv":["2306.12804"]},"day":"05","title":"Zigzag optical cavity for sensing and controlling torsional motion","date_created":"2024-02-12T11:42:18Z","publication_status":"published","citation":{"ieee":"S. Agafonova, U. Mishra, F. R. Diorico, and O. Hosten, “Zigzag optical cavity for sensing and controlling torsional motion,” <i>Physical Review Research</i>, vol. 6, no. 1. American Physical Society, 2024.","chicago":"Agafonova, Sofya, Umang Mishra, Fritz R Diorico, and Onur Hosten. “Zigzag Optical Cavity for Sensing and Controlling Torsional Motion.” <i>Physical Review Research</i>. American Physical Society, 2024. <a href=\"https://doi.org/10.1103/physrevresearch.6.013141\">https://doi.org/10.1103/physrevresearch.6.013141</a>.","mla":"Agafonova, Sofya, et al. “Zigzag Optical Cavity for Sensing and Controlling Torsional Motion.” <i>Physical Review Research</i>, vol. 6, no. 1, 013141, American Physical Society, 2024, doi:<a href=\"https://doi.org/10.1103/physrevresearch.6.013141\">10.1103/physrevresearch.6.013141</a>.","ama":"Agafonova S, Mishra U, Diorico FR, Hosten O. Zigzag optical cavity for sensing and controlling torsional motion. <i>Physical Review Research</i>. 2024;6(1). doi:<a href=\"https://doi.org/10.1103/physrevresearch.6.013141\">10.1103/physrevresearch.6.013141</a>","short":"S. Agafonova, U. Mishra, F.R. Diorico, O. Hosten, Physical Review Research 6 (2024).","ista":"Agafonova S, Mishra U, Diorico FR, Hosten O. 2024. Zigzag optical cavity for sensing and controlling torsional motion. Physical Review Research. 6(1), 013141.","apa":"Agafonova, S., Mishra, U., Diorico, F. R., &#38; Hosten, O. (2024). Zigzag optical cavity for sensing and controlling torsional motion. <i>Physical Review Research</i>. American Physical Society. <a href=\"https://doi.org/10.1103/physrevresearch.6.013141\">https://doi.org/10.1103/physrevresearch.6.013141</a>"},"department":[{"_id":"OnHo"}],"_id":"14980","date_updated":"2024-02-12T11:49:06Z","project":[{"grant_number":"101087907","_id":"bdb2a702-d553-11ed-ba76-f12e3e5a3bc6","name":"A quantum hybrid of atoms and milligram-scale pendulums: towards gravitational quantum mechanics"}],"file_date_updated":"2024-02-12T11:46:50Z"},{"citation":{"ieee":"S. Shen, “Tamely ramified geometric Langlands correspondence in positive characteristic,” <i>International Mathematics Research Notices</i>. Oxford University Press, 2024.","mla":"Shen, Shiyu. “Tamely Ramified Geometric Langlands Correspondence in Positive Characteristic.” <i>International Mathematics Research Notices</i>, Oxford University Press, 2024, doi:<a href=\"https://doi.org/10.1093/imrn/rnae005\">10.1093/imrn/rnae005</a>.","ama":"Shen S. Tamely ramified geometric Langlands correspondence in positive characteristic. <i>International Mathematics Research Notices</i>. 2024. doi:<a href=\"https://doi.org/10.1093/imrn/rnae005\">10.1093/imrn/rnae005</a>","chicago":"Shen, Shiyu. “Tamely Ramified Geometric Langlands Correspondence in Positive Characteristic.” <i>International Mathematics Research Notices</i>. Oxford University Press, 2024. <a href=\"https://doi.org/10.1093/imrn/rnae005\">https://doi.org/10.1093/imrn/rnae005</a>.","apa":"Shen, S. (2024). Tamely ramified geometric Langlands correspondence in positive characteristic. <i>International Mathematics Research Notices</i>. Oxford University Press. <a href=\"https://doi.org/10.1093/imrn/rnae005\">https://doi.org/10.1093/imrn/rnae005</a>","ista":"Shen S. 2024. Tamely ramified geometric Langlands correspondence in positive characteristic. International Mathematics Research Notices.","short":"S. Shen, International Mathematics Research Notices (2024)."},"department":[{"_id":"TaHa"}],"project":[{"grant_number":"101034413","name":"IST-BRIDGE: International postdoctoral program","_id":"fc2ed2f7-9c52-11eb-aca3-c01059dda49c","call_identifier":"H2020"}],"_id":"14986","date_updated":"2024-02-19T10:22:44Z","date_created":"2024-02-14T12:16:17Z","main_file_link":[{"open_access":"1","url":"https://doi.org/10.1093/imrn/rnae005"}],"publication_status":"epub_ahead","acknowledgement":"This work was supported by the NSF [DMS-1502125to S.S.]; and the European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie grant agreement [101034413 to S.S.].\r\nI would like to thank my advisor Tom Nevins for many helpful discussions on this subject and for his comments on this paper. I would like to thank Christopher Dodd, Michael Groechenig, and Tamas Hausel for helpful conversations. I would like to thank Tsao-Hsien Chen for useful comments on an earlier version of this paper.","day":"05","title":"Tamely ramified geometric Langlands correspondence in positive characteristic","external_id":{"arxiv":["1810.12491"]},"year":"2024","oa_version":"Published Version","publication":"International Mathematics Research Notices","arxiv":1,"ec_funded":1,"language":[{"iso":"eng"}],"publication_identifier":{"eissn":["1687-0247"],"issn":["1073-7928"]},"keyword":["General Mathematics"],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","type":"journal_article","doi":"10.1093/imrn/rnae005","oa":1,"publisher":"Oxford University Press","date_published":"2024-02-05T00:00:00Z","abstract":[{"lang":"eng","text":"We prove a version of the tamely ramified geometric Langlands correspondence in positive characteristic for GLn(k). Let k be an algebraically closed field of characteristic p>n. Let X be a smooth projective curve over k with marked points, and fix a parabolic subgroup of GLn(k) at each marked point. We denote by Bunn,P the moduli stack of (quasi-)parabolic vector bundles on X, and by Locn,P the moduli stack of parabolic flat connections such that the residue is nilpotent with respect to the parabolic reduction at each marked point. We construct an equivalence between the bounded derived category Db(Qcoh(Loc0n,P)) of quasi-coherent sheaves on an open substack Loc0n,P⊂Locn,P, and the bounded derived category Db(D0Bunn,P-mod) of D0Bunn,P-modules, where D0Bunn,P is a localization of DBunn,P the sheaf of crystalline differential operators on Bunn,P. Thus we extend the work of Bezrukavnikov-Braverman to the tamely ramified case. We also prove a correspondence between flat connections on X with regular singularities and meromorphic Higgs bundles on the Frobenius twist X(1) of X with first order poles ."}],"quality_controlled":"1","article_type":"original","status":"public","author":[{"first_name":"Shiyu","id":"544cccd3-9005-11ec-87bc-94aef1c5b814","last_name":"Shen","full_name":"Shen, Shiyu"}],"month":"02","article_processing_charge":"Yes (via OA deal)"},{"acknowledgement":"We acknowledge support from the Erasmus programme and the University College London Institute for the Physics of Living Systems (S.C., T.C.T.M., A.Š.), the Biotechnology and Biological Sciences Research Council (T.P.J.K.), the Engineering and Physical Sciences Research Council (D.F.), the European Research Council (T.P.J.K., S.L., D.F., and A.Š.), the Frances and Augustus Newman Foundation (T.P.J.K.), the Academy of Medical Sciences and Wellcome Trust (A.Š.), and the Royal Society (S.C. and A.Š.).","volume":121,"external_id":{"pmid":["38335256"]},"title":"Self-replication of Aβ42 aggregates occurs on small and isolated fibril sites","day":"13","year":"2024","issue":"7","department":[{"_id":"AnSa"}],"citation":{"short":"S. Curk, J. Krausser, G. Meisl, D. Frenkel, S. Linse, T.C.T. Michaels, T.P.J. Knowles, A. Šarić, Proceedings of the National Academy of Sciences of the United States of America 121 (2024).","ista":"Curk S, Krausser J, Meisl G, Frenkel D, Linse S, Michaels TCT, Knowles TPJ, Šarić A. 2024. Self-replication of Aβ42 aggregates occurs on small and isolated fibril sites. Proceedings of the National Academy of Sciences of the United States of America. 121(7), e2220075121.","apa":"Curk, S., Krausser, J., Meisl, G., Frenkel, D., Linse, S., Michaels, T. C. T., … Šarić, A. (2024). Self-replication of Aβ42 aggregates occurs on small and isolated fibril sites. <i>Proceedings of the National Academy of Sciences of the United States of America</i>. Proceedings of the National Academy of Sciences. <a href=\"https://doi.org/10.1073/pnas.2220075121\">https://doi.org/10.1073/pnas.2220075121</a>","chicago":"Curk, Samo, Johannes Krausser, Georg Meisl, Daan Frenkel, Sara Linse, Thomas C.T. Michaels, Tuomas P.J. Knowles, and Anđela Šarić. “Self-Replication of Aβ42 Aggregates Occurs on Small and Isolated Fibril Sites.” <i>Proceedings of the National Academy of Sciences of the United States of America</i>. Proceedings of the National Academy of Sciences, 2024. <a href=\"https://doi.org/10.1073/pnas.2220075121\">https://doi.org/10.1073/pnas.2220075121</a>.","ama":"Curk S, Krausser J, Meisl G, et al. Self-replication of Aβ42 aggregates occurs on small and isolated fibril sites. <i>Proceedings of the National Academy of Sciences of the United States of America</i>. 2024;121(7). doi:<a href=\"https://doi.org/10.1073/pnas.2220075121\">10.1073/pnas.2220075121</a>","mla":"Curk, Samo, et al. “Self-Replication of Aβ42 Aggregates Occurs on Small and Isolated Fibril Sites.” <i>Proceedings of the National Academy of Sciences of the United States of America</i>, vol. 121, no. 7, e2220075121, Proceedings of the National Academy of Sciences, 2024, doi:<a href=\"https://doi.org/10.1073/pnas.2220075121\">10.1073/pnas.2220075121</a>.","ieee":"S. Curk <i>et al.</i>, “Self-replication of Aβ42 aggregates occurs on small and isolated fibril sites,” <i>Proceedings of the National Academy of Sciences of the United States of America</i>, vol. 121, no. 7. Proceedings of the National Academy of Sciences, 2024."},"date_updated":"2024-02-26T08:45:56Z","_id":"15001","file_date_updated":"2024-02-26T08:20:00Z","project":[{"grant_number":"802960","_id":"eba2549b-77a9-11ec-83b8-a81e493eae4e","call_identifier":"H2020","name":"Non-Equilibrium Protein Assembly: from Building Blocks to Biological Machines"}],"date_created":"2024-02-18T23:01:00Z","pmid":1,"license":"https://creativecommons.org/licenses/by-nc-nd/4.0/","publication_status":"published","file":[{"relation":"main_file","date_created":"2024-02-26T08:20:00Z","creator":"dernst","checksum":"5aeb65bcc0dd829b1f9ab307c5031d4b","file_size":7699487,"access_level":"open_access","content_type":"application/pdf","file_id":"15026","success":1,"date_updated":"2024-02-26T08:20:00Z","file_name":"2024_PNAS_Curk.pdf"}],"abstract":[{"text":"Self-replication of amyloid fibrils via secondary nucleation is an intriguing physicochemical phenomenon in which existing fibrils catalyze the formation of their own copies. The molecular events behind this fibril surface-mediated process remain largely inaccessible to current structural and imaging techniques. Using statistical mechanics, computer modeling, and chemical kinetics, we show that the catalytic structure of the fibril surface can be inferred from the aggregation behavior in the presence and absence of a fibril-binding inhibitor. We apply our approach to the case of Alzheimer’s A\r\n amyloid fibrils formed in the presence of proSP-C Brichos inhibitors. We find that self-replication of A\r\n fibrils occurs on small catalytic sites on the fibril surface, which are far apart from each other, and each of which can be covered by a single Brichos inhibitor.","lang":"eng"}],"ddc":["570"],"date_published":"2024-02-13T00:00:00Z","status":"public","article_type":"original","quality_controlled":"1","has_accepted_license":"1","article_number":"e2220075121","scopus_import":"1","article_processing_charge":"Yes","month":"02","author":[{"last_name":"Curk","full_name":"Curk, Samo","first_name":"Samo","orcid":"0000-0001-6160-9766","id":"031eff0d-d481-11ee-8508-cd12a7a86e5b"},{"full_name":"Krausser, Johannes","last_name":"Krausser","first_name":"Johannes"},{"full_name":"Meisl, Georg","last_name":"Meisl","first_name":"Georg"},{"first_name":"Daan","full_name":"Frenkel, Daan","last_name":"Frenkel"},{"full_name":"Linse, Sara","last_name":"Linse","first_name":"Sara"},{"first_name":"Thomas C.T.","full_name":"Michaels, Thomas C.T.","last_name":"Michaels"},{"full_name":"Knowles, Tuomas P.J.","last_name":"Knowles","first_name":"Tuomas P.J."},{"full_name":"Šarić, Anđela","last_name":"Šarić","orcid":"0000-0002-7854-2139","id":"bf63d406-f056-11eb-b41d-f263a6566d8b","first_name":"Anđela"}],"related_material":{"record":[{"status":"public","id":"15027","relation":"research_data"}]},"ec_funded":1,"language":[{"iso":"eng"}],"oa_version":"Published Version","publication":"Proceedings of the National Academy of Sciences of the United States of America","doi":"10.1073/pnas.2220075121","type":"journal_article","publication_identifier":{"eissn":["1091-6490"]},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publisher":"Proceedings of the National Academy of Sciences","oa":1,"intvolume":"       121","tmp":{"short":"CC BY-NC-ND (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","image":"/images/cc_by_nc_nd.png","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)"}}]