---
OA_place: publisher
OA_type: gold
_id: '15331'
abstract:
- lang: eng
  text: This is a test entry.
article_number: '123'
article_processing_charge: No
article_type: original
author:
- first_name: Doris
  full_name: Ernst, Doris
  id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
  last_name: Ernst
  orcid: 0000-0002-2354-0195
biorxivid: 1
citation:
  ama: Ernst D. Test Entry. <i>Try Out</i>. 2026;1(2).
  apa: Ernst, D. (2026). Test Entry. <i>Try Out</i>. Publish Here.
  chicago: Ernst, Doris. “Test Entry.” <i>Try Out</i>. Publish Here, 2026.
  ieee: D. Ernst, “Test Entry,” <i>Try Out</i>, vol. 1, no. 2. Publish Here, 2026.
  ista: Ernst D. 2026. Test Entry. Try Out. 1(2), 123.
  mla: Ernst, Doris. “Test Entry.” <i>Try Out</i>, vol. 1, no. 2, 123, Publish Here,
    2026.
  short: D. Ernst, Try Out 1 (2026).
corr_author: '1'
das_tickbox: '1'
date_created: 2026-03-11T12:44:32Z
date_published: 2026-02-20T00:00:00Z
date_updated: 2026-05-11T14:53:05Z
day: '20'
department:
- _id: E-Lib
external_id:
  biorxivid:
  - 10.64898/2026.03.31.714378
intvolume: '         1'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2302.07339
month: '02'
oa: 1
oa_version: Preprint
publication: Try Out
publication_identifier:
  eisbn:
  - 1234-4321
publication_status: published
publisher: Publish Here
quality_controlled: '1'
retracted: '1'
status: public
title: Test Entry
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 1
year: '2026'
...
---
_id: '15332'
article_processing_charge: No
author:
- first_name: Doris
  full_name: Ernst, Doris
  id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
  last_name: Ernst
  orcid: 0000-0002-2354-0195
citation:
  ama: Ernst D. Plinfa. <i>PokeWiki</i>. 2026.
  apa: Ernst, D. (2026). Plinfa. <i>PokeWiki</i>.
  chicago: Ernst, Doris. “Plinfa.” <i>PokeWiki</i>, 2026.
  ieee: D. Ernst, “Plinfa,” <i>PokeWiki</i>. 2026.
  ista: Ernst D. 2026. Plinfa. PokeWiki.
  mla: Ernst, Doris. “Plinfa.” <i>PokeWiki</i>, 2026.
  short: D. Ernst, PokeWiki (2026).
dataavailabilitystatement: aseradf
date_created: 2026-03-16T11:42:55Z
date_published: 2026-03-16T00:00:00Z
date_updated: 2026-04-30T08:17:02Z
day: '16'
department:
- _id: E-Lib
language:
- iso: eng
month: '03'
oa_version: None
publication: PokeWiki
researchdata_availability: yes (supplementary data)
status: public
supplementarymaterial: no
title: Plinfa
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2026'
...
---
_id: '15333'
article_processing_charge: No
arxiv: 1
author:
- first_name: Doris
  full_name: Ernst, Doris
  id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
  last_name: Ernst
  orcid: 0000-0002-2354-0195
biorxivid: 1
citation:
  ama: Ernst D. Nachtara. <i>PokeWiki</i>. 2026.
  apa: Ernst, D. (2026). Nachtara. <i>PokeWiki</i>.
  chicago: Ernst, Doris. “Nachtara.” <i>PokeWiki</i>, 2026.
  ieee: D. Ernst, “Nachtara,” <i>PokeWiki</i>. 2026.
  ista: Ernst D. 2026. Nachtara. PokeWiki.
  mla: Ernst, Doris. “Nachtara.” <i>PokeWiki</i>, 2026.
  short: D. Ernst, PokeWiki (2026).
das_tickbox: '1'
dataavailabilitystatement: this is my DAS text
date_created: 2026-03-24T14:55:30Z
date_published: 2026-03-24T00:00:00Z
date_updated: 2026-05-13T07:41:26Z
day: '24'
department:
- _id: E-Lib
external_id:
  arxiv:
  - '2212.03121'
  biorxivid:
  - 10.1101/2023.11.30.569337
  chemrxivID:
  - 10.26434/chemrxiv-2025-cxfzs
  cryptoeprintID:
  - 2026/587
  oaworkID:
  - '40417329'
  pmid:
  - sfgadfasdf
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://pokewiki.de/Nachtara
month: '3'
oa: 1
oa_version: None
pmid: 1
publication: PokeWiki
researchdata_availability: yes
status: public
supplementarymaterial: yes
title: Nachtara
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2026'
...
---
_id: '15337'
article_processing_charge: No
author:
- first_name: Doris
  full_name: Ernst, Doris
  id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
  last_name: Ernst
  orcid: 0000-0002-2354-0195
citation:
  ama: Ernst D. Fuegro. <i>PokeWiki</i>. 2026.
  apa: Ernst, D. (2026). Fuegro. <i>PokeWiki</i>.
  chicago: Ernst, Doris. “Fuegro.” <i>PokeWiki</i>, 2026.
  ieee: D. Ernst, “Fuegro,” <i>PokeWiki</i>. 2026.
  ista: Ernst D. 2026. Fuegro. PokeWiki.
  mla: Ernst, Doris. “Fuegro.” <i>PokeWiki</i>, 2026.
  short: D. Ernst, PokeWiki (2026).
date_created: 2026-04-30T05:57:49Z
date_published: 2026-04-30T00:00:00Z
date_updated: 2026-05-13T08:11:16Z
day: '30'
ddc:
- '000'
department:
- _id: E-Lib
file:
- access_level: open_access
  checksum: 8cb95b033ad2a1a7a8181f6f078c05b5
  content_type: application/pdf
  creator: dernst
  date_created: 2026-05-11T14:46:54Z
  date_updated: 2026-05-11T14:46:54Z
  file_id: '15339'
  file_name: 2026_NatureComm_Zambra.pdf
  file_size: 1784917
  relation: main_file
  success: 1
file_date_updated: 2026-05-11T14:46:54Z
has_accepted_license: '1'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
publication: PokeWiki
status: public
title: Fuegro
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2026'
...
---
_id: '15338'
article_processing_charge: No
author:
- first_name: Doris
  full_name: Ernst, Doris
  id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
  last_name: Ernst
  orcid: 0000-0002-2354-0195
citation:
  ama: Ernst D. The world of Pokemon. 2026.
  apa: Ernst, D. (2026). <i>The world of Pokemon</i>.
  chicago: Ernst, Doris. “The World of Pokemon,” 2026.
  ieee: D. Ernst, “The world of Pokemon,” 2026.
  ista: Ernst D. 2026. The world of Pokemon.
  mla: Ernst, Doris. <i>The World of Pokemon</i>. 2026.
  short: D. Ernst, The World of Pokemon, 2026.
date_created: 2026-04-30T08:16:29Z
date_published: 2026-04-30T00:00:00Z
date_updated: 2026-04-30T08:16:56Z
day: '30'
department:
- _id: E-Lib
language:
- iso: eng
month: '04'
oa_version: None
status: public
title: The world of Pokemon
type: dissertation
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2026'
...
---
_id: '15342'
article_processing_charge: No
author:
- first_name: Doris
  full_name: Ernst, Doris
  id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
  last_name: Ernst
  orcid: 0000-0002-2354-0195
citation:
  ama: Ernst D. Pokemon DataSet. 2026.
  apa: Ernst, D. (2026). Pokemon DataSet. ISTA.
  chicago: Ernst, Doris. “Pokemon DataSet.” ISTA, 2026.
  ieee: D. Ernst, “Pokemon DataSet.” ISTA, 2026.
  ista: Ernst D. 2026. Pokemon DataSet, ISTA.
  mla: Ernst, Doris. <i>Pokemon DataSet</i>. ISTA, 2026.
  short: D. Ernst, (2026).
date_created: 2026-05-20T13:43:44Z
date_published: 2026-05-20T00:00:00Z
date_updated: 2026-05-20T13:56:22Z
day: '20'
department:
- _id: E-Lib
doi_confirm: '1'
month: '05'
oa_version: None
publisher: ISTA
status: public
title: Pokemon DataSet
type: research_data
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2026'
...
---
_id: '15346'
abstract:
- lang: eng
  text: I tried my best!
article_processing_charge: No
author:
- first_name: Doris
  full_name: Ernst, Doris
  id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
  last_name: Ernst
  orcid: 0000-0002-2354-0195
citation:
  ama: Ernst D. The science within Pokemon.
  apa: Ernst, D. (n.d.). <i>The science within Pokemon</i>.
  chicago: Ernst, Doris. “The Science within Pokemon,” n.d.
  ieee: D. Ernst, “The science within Pokemon.”
  ista: Ernst D. The science within Pokemon.
  mla: Ernst, Doris. <i>The Science within Pokemon</i>.
  short: D. Ernst, The Science within Pokemon, n.d.
date_created: 2026-05-21T11:34:42Z
date_published: 2026-05-21T00:00:00Z
date_updated: 2026-05-21T11:34:55Z
day: '21'
department:
- _id: E-Lib
language:
- iso: eng
month: '05'
oa_version: None
publication_status: submitted
publisher_comment: You are not allowed to publish this!!!
status: public
title: The science within Pokemon
type: dissertation
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2026'
...
---
PlanS_conform: '1'
_id: '15287'
article_processing_charge: No
article_type: review
arxiv: 1
author:
- first_name: Doris
  full_name: Ernst, Doris
  id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
  last_name: Ernst
  orcid: 0000-0002-2354-0195
citation:
  ama: Ernst D. awera. <i>asdfew</i>. 2025.
  apa: Ernst, D. (2025). awera. <i>Asdfew</i>.
  chicago: Ernst, Doris. “Awera.” <i>Asdfew</i>, 2025.
  ieee: D. Ernst, “awera,” <i>asdfew</i>. 2025.
  ista: Ernst D. 2025. awera. asdfew.
  mla: Ernst, Doris. “Awera.” <i>Asdfew</i>, 2025.
  short: D. Ernst, Asdfew (2025).
date_created: 2025-07-08T07:01:03Z
date_published: 2025-07-08T00:00:00Z
date_updated: 2025-08-13T10:50:58Z
day: '08'
ddc:
- '000'
department:
- _id: E-Lib
ec_funded: 1
external_id:
  arxiv:
  - '1711.01986'
  oaworkID:
  - W3021112752
file:
- access_level: open_access
  checksum: 144b0e46aa3dff0cdf8c6ee7d4fe2fe4
  content_type: application/pdf
  creator: dernst
  date_created: 2025-07-10T12:14:23Z
  date_updated: 2025-07-10T12:14:23Z
  file_id: '15288'
  file_name: 2025_AstronomicalJour_Cheng.pdf
  file_size: 931173
  relation: main_file
  success: 1
file_date_updated: 2025-07-10T12:14:23Z
has_accepted_license: '1'
language:
- iso: eng
month: '07'
oa: 1
oa_version: None
project:
- _id: 6852f906-53e7-11ef-a9e7-e97db7813225
  grant_number: '987654'
  name: After a long, long time...
- _id: bdaf81a8-d553-11ed-ba76-c95961984540
  grant_number: '101086580'
  name: 'Action Selection in the Midbrain: Neuromodulation of Visuomotor Senses'
- _id: 26336814-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '758053'
  name: A Fiber Optic Transceiver for Superconducting Qubits
- _id: 34b44cb4-11ca-11ed-8bc3-ee02a162ebbd
  grant_number: ESP106-N
  name: A new probe of multipole physics in Prbased compounds
publication: asdfew
status: public
title: awera
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2025'
...
---
_id: '15307'
article_processing_charge: No
author:
- first_name: Doris
  full_name: Ernst, Doris
  id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
  last_name: Ernst
  orcid: 0000-0002-2354-0195
citation:
  ama: Ernst D. Troll. <i>Trollhausen</i>. 2025.
  apa: Ernst, D. (2025). Troll. <i>Trollhausen</i>. Trollingten.
  chicago: Ernst, Doris. “Troll.” <i>Trollhausen</i>. Trollingten, 2025.
  ieee: D. Ernst, “Troll,” <i>Trollhausen</i>. Trollingten, 2025.
  ista: Ernst D. 2025. Troll. Trollhausen.
  mla: Ernst, Doris. “Troll.” <i>Trollhausen</i>, Trollingten, 2025.
  short: D. Ernst, Trollhausen (2025).
das_tickbox: '1'
date_created: 2025-08-12T10:21:09Z
date_published: 2025-08-12T00:00:00Z
date_updated: 2026-04-02T09:51:57Z
day: '12'
department:
- _id: E-Lib
external_id:
  chemrxivID:
  - 10.26434/chemrxiv.15001524
genbank:
- A45B12
- '12345'
keyword:
- Norway
- Troll
- Fjell
language:
- iso: eng
month: '08'
oa_version: None
publication: Trollhausen
publisher: Trollingten
status: public
title: Troll
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2025'
...
---
_id: '15310'
article_processing_charge: No
arxiv: 1
author:
- first_name: Doris
  full_name: Ernst, Doris
  id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
  last_name: Ernst
  orcid: 0000-0002-2354-0195
citation:
  ama: Ernst D. <i>Vacation</i>. Springer Nature
  apa: Ernst, D. (n.d.). <i>Vacation</i>. Springer Nature.
  chicago: Ernst, Doris. <i>Vacation</i>. Springer Nature, n.d.
  ieee: D. Ernst, <i>Vacation</i>. Springer Nature.
  ista: Ernst D. Vacation, Springer Nature,p.
  mla: Ernst, Doris. <i>Vacation</i>. Springer Nature.
  short: D. Ernst, Vacation, Springer Nature, n.d.
date_created: 2025-08-13T12:57:26Z
date_published: 2025-08-13T00:00:00Z
date_updated: 2025-09-08T09:20:01Z
day: '13'
department:
- _id: E-Lib
external_id:
  arxiv:
  - '2508.12345'
  oaworkID:
  - w4390499170
  pmid:
  - '39792900'
keyword:
- Frustrating
language:
- iso: eng
month: '08'
oa_version: None
pmid: 1
publication_status: submitted
publisher: Springer Nature
status: public
title: Vacation
type: book
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2025'
...
---
_id: '15315'
article_processing_charge: No
author:
- first_name: Doris
  full_name: Ernst, Doris
  id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
  last_name: Ernst
  orcid: 0000-0002-2354-0195
citation:
  ama: Ernst D. Pikachu. <i>PokeWiki</i>. 2025.
  apa: Ernst, D. (2025). Pikachu. <i>PokeWiki</i>.
  chicago: Ernst, Doris. “Pikachu.” <i>PokeWiki</i>, 2025.
  ieee: D. Ernst, “Pikachu,” <i>PokeWiki</i>. 2025.
  ista: Ernst D. 2025. Pikachu. PokeWiki, .
  mla: Ernst, Doris. “Pikachu.” <i>PokeWiki</i>, 2025.
  short: D. Ernst, PokeWiki (2025).
date_created: 2025-09-08T09:52:38Z
date_published: 2025-09-08T00:00:00Z
date_updated: 2025-09-08T11:12:52Z
day: '08'
department:
- _id: E-Lib
keyword:
- Pokemon
- Elektro
language:
- iso: eng
month: '09'
oa_version: None
publication: PokeWiki
status: public
title: Pikachu
type: preprint
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2025'
...
---
_id: '15316'
article_processing_charge: No
author:
- first_name: Doris
  full_name: Ernst, Doris
  id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
  last_name: Ernst
  orcid: 0000-0002-2354-0195
citation:
  ama: Ernst D. Raichu. <i>PokeWiki</i>. 2025.
  apa: Ernst, D. (2025). Raichu. <i>PokeWiki</i>.
  chicago: Ernst, Doris. “Raichu.” <i>PokeWiki</i>, 2025.
  ieee: D. Ernst, “Raichu,” <i>PokeWiki</i>. 2025.
  ista: Ernst D. 2025. Raichu. PokeWiki.
  mla: Ernst, Doris. “Raichu.” <i>PokeWiki</i>, 2025.
  short: D. Ernst, PokeWiki (2025).
date_created: 2025-09-08T11:14:44Z
date_published: 2025-09-08T00:00:00Z
date_updated: 2026-03-02T15:52:31Z
day: '08'
department:
- _id: E-Lib
genbank:
- A45B12
- '12345'
keyword:
- Pokemon
- Nintendo
language:
- iso: eng
month: '09'
oa_version: None
publication: PokeWiki
status: public
title: Raichu
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2025'
...
---
OA_place: repository
OA_type: green
_id: '12312'
abstract:
- lang: eng
  text: "Let $\\ell$ be a prime number. We classify the subgroups $G$ of $\\operatorname{Sp}_4(\\mathbb{F}_\\ell)$
    and $\\operatorname{GSp}_4(\\mathbb{F}_\\ell)$ that act irreducibly on $\\mathbb{F}_\\ell^4$,
    but such that every element of $G$ fixes an $\\mathbb{F}_\\ell$-vector subspace
    of dimension 1. We use this classification to prove that the local-global principle
    for isogenies of degree $\\ell$ between abelian surfaces over number fields holds
    in many cases -- in particular, whenever the abelian surface has non-trivial endomorphisms
    and $\\ell$ is large enough with respect to the field of definition. Finally,
    we prove that there exist arbitrarily large primes $\\ell$ for which some abelian
    surface\r\n$A/\\mathbb{Q}$ fails the local-global principle for isogenies of degree
    $\\ell$."
acknowledgement: "It is a pleasure to thank Samuele Anni for his interest in this
  project and for several discussions on the topic of this paper, which led in particular
  to Remark 6.30 and to a better understanding of the difficulties with [6]. We also
  thank John Cullinan for correspondence about [6] and Barinder Banwait for his many
  insightful comments on the first version of this paper. Finally, we thank the referee
  for their thorough reading of the manuscript.\r\nOpen access funding provided by
  Università di Pisa within the CRUI-CARE Agreement. The authors have been partially
  supported by MIUR (Italy) through PRIN 2017 “Geometric, algebraic and analytic methods
  in arithmetic\" and PRIN 2022 “Semiabelian varieties, Galois representations and
  related Diophantine problems\", and by the University of Pisa through PRA 2018-19
  and 2022 “Spazi di moduli, rappresentazioni e strutture combinatorie\". The first
  author is a member of the INdAM group GNSAGA."
article_number: '18'
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Davide
  full_name: Lombardo, Davide
  last_name: Lombardo
- first_name: Matteo
  full_name: Verzobio, Matteo
  id: 7aa8f170-131e-11ed-88e1-a9efd01027cb
  last_name: Verzobio
  orcid: 0000-0002-0854-0306
date_created: 2023-01-16T11:45:53Z
date_published: 2024-01-26T00:00:00Z
date_updated: 2025-02-13T11:47:12Z
day: '26'
department:
- _id: TiBr
doi: 10.1007/s00029-023-00908-0
external_id:
  arxiv:
  - '2206.15240'
intvolume: '        30'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/2206.15240
month: '01'
oa: 1
oa_version: Preprint
publication: Selecta Mathematica
publication_identifier:
  eissn:
  - 1420-9020
  issn:
  - 4321-1234
  issnl:
  - 1022-1824
publication_status: epub_ahead
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: On the local-global principle for isogenies of abelian surfaces
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 30
year: '2024'
...
---
_id: '12875'
abstract:
- lang: eng
  text: The superior colliculus (SC) in the mammalian midbrain is essential for multisensory
    integration and is composed of a rich diversity of excitatory and inhibitory neurons
    and glia. However, the developmental principles directing the generation of SC
    cell-type diversity are not understood. Here, we pursued systematic cell lineage
    tracing in silico and in vivo, preserving full spatial information, using genetic
    mosaic analysis with double markers (MADM)-based clonal analysis with single-cell
    sequencing (MADM-CloneSeq). The analysis of clonally related cell lineages revealed
    that radial glial progenitors (RGPs) in SC are exceptionally multipotent. Individual
    resident RGPs have the capacity to produce all excitatory and inhibitory SC neuron
    types, even at the stage of terminal division. While individual clonal units show
    no pre-defined cellular composition, the establishment of appropriate relative
    proportions of distinct neuronal types occurs in a PTEN-dependent manner. Collectively,
    our findings provide an inaugural framework at the single-RGP/-cell level of the
    mammalian SC ontogeny.
acknowledged_ssus:
- _id: Bio
- _id: M-Shop
- _id: LifeSc
- _id: PreCl
acknowledgement: "We thank Liqun Luo for his continued support, for providing essential
  resources for generating Fzd10-CreER mice which were generated in his laboratory,
  and for comments on the manuscript; W. Zhong for providing Nestin-Cre transgenic
  mouse line for this study; A. Heger for mouse colony management; R. Beattie and
  T. Asenov for designing and producing components of acute slice recovery chamber
  for MADM-CloneSeq experiments; and K. Leopold, J. Rodarte and N. Amberg for initial
  experiments, technical support and/or assistance. This study was supported by the
  Scientific Service Units (SSU) of IST Austria through resources provided by the
  Imaging & Optics Facility (IOF), Laboratory Support Facility (LSF), Miba Machine
  Shop, and Pre-clinical Facility (PCF). G.C. received funding from European Commission
  (IST plus postdoctoral fellowship). This work was supported by ISTA institutional\r\nfunds;
  the Austrian Science Fund Special Research Programmes (FWF SFB F78 Neuro Stem Modulation)
  to S.H. "
article_processing_charge: Yes (via OA deal)
article_type: comment
author:
- first_name: Giselle T
  full_name: Cheung, Giselle T
  id: 471195F6-F248-11E8-B48F-1D18A9856A87
  last_name: Cheung
  orcid: 0000-0001-8457-2572
- first_name: Florian
  full_name: Pauler, Florian
  id: 48EA0138-F248-11E8-B48F-1D18A9856A87
  last_name: Pauler
  orcid: 0000-0002-7462-0048
- first_name: Peter
  full_name: Koppensteiner, Peter
  id: 3B8B25A8-F248-11E8-B48F-1D18A9856A87
  last_name: Koppensteiner
  orcid: 0000-0002-3509-1948
- first_name: Thomas
  full_name: Krausgruber, Thomas
  last_name: Krausgruber
- first_name: Carmen
  full_name: Streicher, Carmen
  id: 36BCB99C-F248-11E8-B48F-1D18A9856A87
  last_name: Streicher
- first_name: Martin
  full_name: Schrammel, Martin
  id: f13e7cae-e8bd-11ed-841a-96dedf69f46d
  last_name: Schrammel
- first_name: Natalie Y
  full_name: Özgen, Natalie Y
  id: e68ece33-f6e0-11ea-865d-ae1031dcc090
  last_name: Özgen
- first_name: Alexis
  full_name: Ivec, Alexis
  id: 1d144691-e8be-11ed-9b33-bdd3077fad4c
  last_name: Ivec
- first_name: Christoph
  full_name: Bock, Christoph
  last_name: Bock
- first_name: Ryuichi
  full_name: Shigemoto, Ryuichi
  id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
  last_name: Shigemoto
  orcid: 0000-0001-8761-9444
- first_name: Simon
  full_name: Hippenmeyer, Simon
  id: 37B36620-F248-11E8-B48F-1D18A9856A87
  last_name: Hippenmeyer
  orcid: 0000-0003-2279-1061
date_created: 2023-04-27T09:41:48Z
date_published: 2024-01-17T00:00:00Z
date_updated: 2025-05-14T09:39:37Z
day: '17'
ddc:
- '570'
department:
- _id: SiHi
- _id: RySh
doi: 10.1016/j.neuron.2023.11.009
external_id:
  pmid:
  - '38096816'
file:
- access_level: open_access
  checksum: 32b3788f7085cf44a84108d8faaff3ce
  content_type: application/pdf
  creator: dernst
  date_created: 2024-02-06T13:56:15Z
  date_updated: 2024-02-06T13:56:15Z
  file_id: '14944'
  file_name: 2024_Neuron_Cheung.pdf
  file_size: 5942467
  relation: main_file
  success: 1
file_date_updated: 2024-02-06T13:56:15Z
has_accepted_license: '1'
intvolume: '       112'
issue: '2'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: 230-246.e11
pmid: 1
project:
- _id: 059F6AB4-7A3F-11EA-A408-12923DDC885E
  grant_number: F07805
  name: Molecular Mechanisms of Neural Stem Cell Lineage Progression
publication: Neuron
publication_identifier:
  eisbn:
  - '1234995621'
  issn:
  - 0896-6273
  issnl:
  - 1234-5678
publication_status: published
publisher: Elsevier
quality_controlled: '1'
related_material:
  link:
  - description: News on ISTA Website
    relation: press_release
    url: https://ista.ac.at/en/news/the-pedigree-of-brain-cells/
scopus_import: '1'
status: public
title: Multipotent progenitors instruct ontogeny of the superior colliculus
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 112
year: '2024'
...
---
_id: '14213'
abstract:
- lang: eng
  text: We introduce a method to segment the visual field into independently moving
    regions, trained with no ground truth or supervision. It consists of an adversarial
    conditional encoder-decoder architecture based on Slot Attention, modified to
    use the image as context to decode optical flow without attempting to reconstruct
    the image itself. In the resulting multi-modal representation, one modality (flow)
    feeds the encoder to produce separate latent codes (slots), whereas the other
    modality (image) conditions the decoder to generate the first (flow) from the
    slots. This design frees the representation from having to encode complex nuisance
    variability in the image due to, for instance, illumination and reflectance properties
    of the scene. Since customary autoencoding based on minimizing the reconstruction
    error does not preclude the entire flow from being encoded into a single slot,
    we modify the loss to an adversarial criterion based on Contextual Information
    Separation. The resulting min-max optimization fosters the separation of objects
    and their assignment to different attention slots, leading to Divided Attention,
    or DivA. DivA outperforms recent unsupervised multi-object motion segmentation
    methods while tripling run-time speed up to 104FPS and reducing the performance
    gap from supervised methods to 12% or less. DivA can handle different numbers
    of objects and different image sizes at training and test time, is invariant to
    permutation of object labels, and does not require explicit regularization.
article_processing_charge: No
arxiv: 1
author:
- first_name: Dong
  full_name: Lao, Dong
  last_name: Lao
- first_name: Zhengyang
  full_name: Hu, Zhengyang
  last_name: Hu
- first_name: Francesco
  full_name: Locatello, Francesco
  id: 26cfd52f-2483-11ee-8040-88983bcc06d4
  last_name: Locatello
  orcid: 0000-0002-4850-0683
- first_name: Yanchao
  full_name: Yang, Yanchao
  last_name: Yang
- first_name: Stefano
  full_name: Soatto, Stefano
  last_name: Soatto
conference:
  end_date: 2024-01-03
  location: Hong Kong, China
  name: 'CPAL: Conference on Parsimony and Learning'
  start_date: 2024-01-03
date_created: 2023-08-22T14:19:59Z
date_published: 2024-01-03T00:00:00Z
date_updated: 2025-02-13T08:10:28Z
day: '03'
ddc:
- '000'
department:
- _id: FrLo
external_id:
  arxiv:
  - '2304.01430'
file:
- access_level: open_access
  checksum: 8fad894c34f1b3d5a14fb8ffb12f7277
  content_type: application/pdf
  creator: dernst
  date_created: 2024-02-12T08:40:36Z
  date_updated: 2024-02-12T08:40:36Z
  file_id: '14978'
  file_name: 2024_CPAL_Lao.pdf
  file_size: 8038511
  relation: main_file
  success: 1
file_date_updated: 2024-02-12T08:40:36Z
has_accepted_license: '1'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
publication: 1st Conference on Parsimony and Learning
publication_identifier:
  issnl:
  - 1234-4321
publication_status: published
quality_controlled: '1'
status: public
title: 'Divided attention: Unsupervised multi-object discovery with contextually separated
  slots'
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2024'
...
---
_id: '14251'
abstract:
- lang: eng
  text: The phytohormone auxin and its directional transport through tissues play
    a fundamental role in development of higher plants. This polar auxin transport
    predominantly relies on PIN-FORMED (PIN) auxin exporters. Hence, PIN polarization
    is crucial for development, but its evolution during the rise of morphological
    complexity in land plants remains unclear. Here, we performed a cross-species
    investigation by observing the trafficking and localization of endogenous and
    exogenous PINs in two bryophytes, Physcomitrium patens and Marchantia polymorpha,
    and in the flowering plant Arabidopsis thaliana. We confirmed that the GFP fusion
    did not compromise the auxin export function of all examined PINs by using radioactive
    auxin export assay and by observing the phenotypic changes in transgenic bryophytes.
    Endogenous PINs polarize to filamentous apices, while exogenous Arabidopsis PINs
    distribute symmetrically on the membrane in both bryophytes. In Arabidopsis root
    epidermis, bryophytic PINs show no defined polarity. Pharmacological interference
    revealed a strong cytoskeleton dependence of bryophytic but not Arabidopsis PIN
    polarization. The divergence of PIN polarization and trafficking is also observed
    within the bryophyte clade and between tissues of individual species. These results
    collectively reveal a divergence of PIN trafficking and polarity mechanisms throughout
    land plant evolution and a co-evolution of PIN sequence-based and cell-based polarity
    mechanisms.
acknowledgement: This work was supported by the ERC grant (PR1023ERC02) to H. T. and
  J. F., and by the ministry of science and technology (grant number 110-2636-B-005-001)
  to K. J. L.
article_number: '100669'
article_processing_charge: Yes
article_type: original
author:
- first_name: Han
  full_name: Tang, Han
  id: 19BDF720-25A0-11EA-AC6E-928F3DDC885E
  last_name: Tang
  orcid: 0000-0001-6152-6637
- first_name: KJ
  full_name: Lu, KJ
  last_name: Lu
- first_name: Y
  full_name: Zhang, Y
  last_name: Zhang
- first_name: YL
  full_name: Cheng, YL
  last_name: Cheng
- first_name: SL
  full_name: Tu, SL
  last_name: Tu
- first_name: Jiří
  full_name: Friml, Jiří
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
citation:
  ama: Tang H, Lu K, Zhang Y, Cheng Y, Tu S, Friml J. Divergence of trafficking and
    polarization mechanisms for PIN auxin transporters during land plant evolution.
    <i>Plant Communications</i>. 2024;5(1). doi:<a href="https://doi.org/10.1016/j.xplc.2023.100669">10.1016/j.xplc.2023.100669</a>
  apa: Tang, H., Lu, K., Zhang, Y., Cheng, Y., Tu, S., &#38; Friml, J. (2024). Divergence
    of trafficking and polarization mechanisms for PIN auxin transporters during land
    plant evolution. <i>Plant Communications</i>. Elsevier. <a href="https://doi.org/10.1016/j.xplc.2023.100669">https://doi.org/10.1016/j.xplc.2023.100669</a>
  chicago: Tang, Han, KJ Lu, Y Zhang, YL Cheng, SL Tu, and Jiří Friml. “Divergence
    of Trafficking and Polarization Mechanisms for PIN Auxin Transporters during Land
    Plant Evolution.” <i>Plant Communications</i>. Elsevier, 2024. <a href="https://doi.org/10.1016/j.xplc.2023.100669">https://doi.org/10.1016/j.xplc.2023.100669</a>.
  ieee: H. Tang, K. Lu, Y. Zhang, Y. Cheng, S. Tu, and J. Friml, “Divergence of trafficking
    and polarization mechanisms for PIN auxin transporters during land plant evolution,”
    <i>Plant Communications</i>, vol. 5, no. 1. Elsevier, 2024.
  ista: Tang H, Lu K, Zhang Y, Cheng Y, Tu S, Friml J. 2024. Divergence of trafficking
    and polarization mechanisms for PIN auxin transporters during land plant evolution.
    Plant Communications. 5(1), 100669.
  mla: Tang, Han, et al. “Divergence of Trafficking and Polarization Mechanisms for
    PIN Auxin Transporters during Land Plant Evolution.” <i>Plant Communications</i>,
    vol. 5, no. 1, 100669, Elsevier, 2024, doi:<a href="https://doi.org/10.1016/j.xplc.2023.100669">10.1016/j.xplc.2023.100669</a>.
  short: H. Tang, K. Lu, Y. Zhang, Y. Cheng, S. Tu, J. Friml, Plant Communications
    5 (2024).
date_created: 2023-09-01T11:32:02Z
date_published: 2024-01-08T00:00:00Z
date_updated: 2025-07-02T12:51:02Z
day: '08'
ddc:
- '580'
department:
- _id: JiFr
doi: 10.1016/j.xplc.2023.100669
ec_funded: 1
external_id:
  pmid:
  - '37528584'
file:
- access_level: open_access
  checksum: edbc44c6d4a394d2bf70f92fdbb08f0a
  content_type: application/pdf
  creator: dernst
  date_created: 2024-01-30T12:59:57Z
  date_updated: 2024-01-30T12:59:57Z
  file_id: '14911'
  file_name: 2023_PlantCommunications_Tang.pdf
  file_size: 2825565
  relation: main_file
  success: 1
file_date_updated: 2024-01-30T12:59:57Z
has_accepted_license: '1'
intvolume: '         5'
issue: '1'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 261099A6-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '742985'
  name: Tracing Evolution of Auxin Transport and Polarity in Plants
publication: Plant Communications
publication_identifier:
  issn:
  - 2590-3462
  issnl:
  - 1234-4567
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Divergence of trafficking and polarization mechanisms for PIN auxin transporters
  during land plant evolution
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 5
year: '2024'
...
---
_id: '14479'
abstract:
- lang: eng
  text: 'In animals, parasitic infections impose significant fitness costs.1,2,3,4,5,6
    Infected animals can alter their feeding behavior to resist infection,7,8,9,10,11,12
    but parasites can manipulate animal foraging behavior to their own benefits.13,14,15,16
    How nutrition influences host-parasite interactions is not well understood, as
    studies have mainly focused on the host and less on the parasite.9,12,17,18,19,20,21,22,23
    We used the nutritional geometry framework24 to investigate the role of amino
    acids (AA) and carbohydrates (C) in a host-parasite system: the Argentine ant,
    Linepithema humile, and the entomopathogenic fungus, Metarhizium brunneum. First,
    using 18 diets varying in AA:C composition, we established that the fungus performed
    best on the high-amino-acid diet 1:4. Second, we found that the fungus reached
    this optimal diet when given various diet pairings, revealing its ability to cope
    with nutritional challenges. Third, we showed that the optimal fungal diet reduced
    the lifespan of healthy ants when compared with a high-carbohydrate diet but had
    no effect on infected ants. Fourth, we revealed that infected ant colonies, given
    a choice between the optimal fungal diet and a high-carbohydrate diet, chose the
    optimal fungal diet, whereas healthy colonies avoided it. Lastly, by disentangling
    fungal infection from host immune response, we demonstrated that infected ants
    foraged on the optimal fungal diet in response to immune activation and not as
    a result of parasite manipulation. Therefore, we revealed that infected ant colonies
    chose a diet that is costly for survival in the long term but beneficial in the
    short term—a form of collective self-medication.'
acknowledgement: We are sincerely grateful to the referees for their valuable comments
  and suggestions, which helped us to improve the paper. We are thankful to Jorgen
  Eilenberg and Nicolai V. Meyling for the fungal strain, to Simon Tragust, Abel Bernadou,
  and Brian Lazarro for insightful discussions, to Iago Sanmartín-Villar, Léa Briard,
  Céline Maitrel, and Nolwenn Rissen for their help with the experiments. Furthermore,
  we thank Anna V. Grasse for help with the immune gene expression analyses. We thank
  Sergio Ibarra for creating the graphical abstract. E.C. was supported by a Fyssen
  Foundation grant and the Alexander von Humboldt Foundation. A.D. was supported by
  the CNRS.
article_processing_charge: No
article_type: original
author:
- first_name: Eniko
  full_name: Csata, Eniko
  last_name: Csata
- first_name: Alfonso
  full_name: Perez-Escudero, Alfonso
  last_name: Perez-Escudero
- first_name: Emmanuel
  full_name: Laury, Emmanuel
  last_name: Laury
- first_name: Hanna
  full_name: Leitner, Hanna
  id: 8fc5c6f6-5903-11ec-abad-c83f046253e7
  last_name: Leitner
- first_name: Gerard
  full_name: Latil, Gerard
  last_name: Latil
- first_name: Juerge
  full_name: Heinze, Juerge
  last_name: Heinze
- first_name: Stephen
  full_name: Simpson, Stephen
  last_name: Simpson
- first_name: Sylvia
  full_name: Cremer, Sylvia
  id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
  last_name: Cremer
  orcid: 0000-0002-2193-3868
- first_name: Audrey
  full_name: Dussutour, Audrey
  last_name: Dussutour
citation:
  ama: Csata E, Perez-Escudero A, Laury E, et al. Fungal infection alters collective
    nutritional intake of ant colonies. <i>Current Biology</i>. 2024;34(4):902-909.e6.
    doi:<a href="https://doi.org/10.1016/j.cub.2024.01.017">10.1016/j.cub.2024.01.017</a>
  apa: Csata, E., Perez-Escudero, A., Laury, E., Leitner, H., Latil, G., Heinze, J.,
    … Dussutour, A. (2024). Fungal infection alters collective nutritional intake
    of ant colonies. <i>Current Biology</i>. Elsevier. <a href="https://doi.org/10.1016/j.cub.2024.01.017">https://doi.org/10.1016/j.cub.2024.01.017</a>
  chicago: Csata, Eniko, Alfonso Perez-Escudero, Emmanuel Laury, Hanna Leitner, Gerard
    Latil, Juerge Heinze, Stephen Simpson, Sylvia Cremer, and Audrey Dussutour. “Fungal
    Infection Alters Collective Nutritional Intake of Ant Colonies.” <i>Current Biology</i>.
    Elsevier, 2024. <a href="https://doi.org/10.1016/j.cub.2024.01.017">https://doi.org/10.1016/j.cub.2024.01.017</a>.
  ieee: E. Csata <i>et al.</i>, “Fungal infection alters collective nutritional intake
    of ant colonies,” <i>Current Biology</i>, vol. 34, no. 4. Elsevier, p. 902–909.e6,
    2024.
  ista: Csata E, Perez-Escudero A, Laury E, Leitner H, Latil G, Heinze J, Simpson
    S, Cremer S, Dussutour A. 2024. Fungal infection alters collective nutritional
    intake of ant colonies. Current Biology. 34(4), 902–909.e6.
  mla: Csata, Eniko, et al. “Fungal Infection Alters Collective Nutritional Intake
    of Ant Colonies.” <i>Current Biology</i>, vol. 34, no. 4, Elsevier, 2024, p. 902–909.e6,
    doi:<a href="https://doi.org/10.1016/j.cub.2024.01.017">10.1016/j.cub.2024.01.017</a>.
  short: E. Csata, A. Perez-Escudero, E. Laury, H. Leitner, G. Latil, J. Heinze, S.
    Simpson, S. Cremer, A. Dussutour, Current Biology 34 (2024) 902–909.e6.
dataavailabilitystatement: no DAS
date_created: 2023-10-31T13:30:20Z
date_published: 2024-02-26T00:00:00Z
date_updated: 2026-03-18T11:15:21Z
day: '26'
department:
- _id: SyCr
doi: 10.1016/j.cub.2024.01.017
external_id:
  pmid:
  - '38307022'
intvolume: '        34'
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1101/2023.10.26.564092
month: '02'
oa: 1
oa_version: Preprint
page: 902-909.e6
pmid: 1
publication: Current Biology
publication_identifier:
  eissn:
  - 1879-0445
  issn:
  - 0960-9822
  issnl:
  - 1234-5678
publication_status: published
publisher: Elsevier
quality_controlled: '1'
researchdata_availability: unclear
scopus_import: '1'
status: public
supplementarymaterial: yes
title: Fungal infection alters collective nutritional intake of ant colonies
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 34
year: '2024'
...
---
_id: '14705'
abstract:
- lang: eng
  text: Since the commercialization of brine shrimp (genus Artemia) in the 1950s,
    this lineage, and in particular the model species Artemia franciscana, has been
    the subject of extensive research. However, our understanding of the genetic mechanisms
    underlying various aspects of their reproductive biology, including sex determination,
    are still lacking. This is partly due to the scarcity of genomic resources for
    Artemia species and crustaceans in general. Here, we present a chromosome-level
    genome assembly of Artemia franciscana (Kellogg 1906), from the Great Salt Lake,
    USA. The genome is 1GB, and the majority of the genome (81%) is scaffolded into
    21 linkage groups using a previously published high-density linkage map. We performed
    coverage and FST analyses using male and female genomic and transcriptomic reads
    to quantify the extent of differentiation between the Z and W chromosomes. Additionally,
    we quantified the expression levels in male and female heads and gonads and found
    further evidence for dosage compensation in this species.
article_processing_charge: No
author:
- first_name: Marwan N
  full_name: Elkrewi, Marwan N
  id: 0B46FACA-A8E1-11E9-9BD3-79D1E5697425
  last_name: Elkrewi
  orcid: 0000-0002-5328-7231
citation:
  ama: Elkrewi MN. Data from “Chromosome-level assembly of Artemia franciscana sheds
    light on sex-chromosome differentiation.” 2024. doi:<a href="https://doi.org/10.15479/AT:ISTA:14705">10.15479/AT:ISTA:14705</a>
  apa: Elkrewi, M. N. (2024). Data from “Chromosome-level assembly of Artemia franciscana
    sheds light on sex-chromosome differentiation.” Institute of Science and Technology
    Austria. <a href="https://doi.org/10.15479/AT:ISTA:14705">https://doi.org/10.15479/AT:ISTA:14705</a>
  chicago: Elkrewi, Marwan N. “Data from ‘Chromosome-Level Assembly of Artemia Franciscana
    Sheds Light on Sex-Chromosome Differentiation.’” Institute of Science and Technology
    Austria, 2024. <a href="https://doi.org/10.15479/AT:ISTA:14705">https://doi.org/10.15479/AT:ISTA:14705</a>.
  ieee: M. N. Elkrewi, “Data from ‘Chromosome-level assembly of Artemia franciscana
    sheds light on sex-chromosome differentiation.’” Institute of Science and Technology
    Austria, 2024.
  ista: Elkrewi MN. 2024. Data from ‘Chromosome-level assembly of Artemia franciscana
    sheds light on sex-chromosome differentiation’, Institute of Science and Technology
    Austria, <a href="https://doi.org/10.15479/AT:ISTA:14705">10.15479/AT:ISTA:14705</a>.
  mla: Elkrewi, Marwan N. <i>Data from “Chromosome-Level Assembly of Artemia Franciscana
    Sheds Light on Sex-Chromosome Differentiation.”</i> Institute of Science and Technology
    Austria, 2024, doi:<a href="https://doi.org/10.15479/AT:ISTA:14705">10.15479/AT:ISTA:14705</a>.
  short: M.N. Elkrewi, (2024).
contributor:
- contributor_type: researcher
  first_name: Vincent K
  id: 57854184-AAE0-11E9-8D04-98D6E5697425
  last_name: Bett
- contributor_type: project_member
  first_name: Ariana
  id: 2A0848E2-F248-11E8-B48F-1D18A9856A87
  last_name: Macon
- contributor_type: supervisor
  first_name: Beatriz
  id: 49E1C5C6-F248-11E8-B48F-1D18A9856A87
  last_name: Vicoso
  orcid: 0000-0002-4579-8306
- contributor_type: researcher
  first_name: Marwan N
  id: 0B46FACA-A8E1-11E9-9BD3-79D1E5697425
  last_name: Elkrewi
  orcid: 0000-0002-5328-7231
date_created: 2023-12-22T13:40:48Z
date_published: 2024-01-02T00:00:00Z
date_updated: 2026-05-18T12:46:40Z
day: '02'
ddc:
- '576'
department:
- _id: GradSch
- _id: BeVi
doi: 10.15479/AT:ISTA:14705
has_accepted_license: '1'
keyword:
- sex chromosome evolution
- genome assembly
- dosage compensation
month: '01'
oa_version: Published Version
project:
- _id: 34ae1506-11ca-11ed-8bc3-c14f4c474396
  grant_number: F8810
  name: The highjacking of meiosis for asexual reproduction
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '15009'
    relation: used_in_publication
    status: public
retracted: '1'
status: public
title: Data from "Chromosome-level assembly of Artemia franciscana sheds light on
  sex-chromosome differentiation"
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: research_data
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2024'
...
---
_id: '14711'
abstract:
- lang: eng
  text: "In nature, different species find their niche in a range of environments,
    each with its unique characteristics. While some thrive in uniform (homogeneous)
    landscapes where environmental conditions stay relatively consistent across space,
    others traverse the complexities of spatially heterogeneous terrains. Comprehending
    how species are distributed and how they interact within these landscapes holds
    the key to gaining insights into their evolutionary dynamics while also informing
    conservation and management strategies.\r\n\r\nFor species inhabiting heterogeneous
    landscapes, when the rate of dispersal is low compared to spatial fluctuations
    in selection pressure, localized adaptations may emerge. Such adaptation in response
    to varying selection strengths plays an important role in the persistence of populations
    in our rapidly changing world. Hence, species in nature are continuously in a
    struggle to adapt to local environmental conditions, to ensure their continued
    survival. Natural populations can often adapt in time scales short enough for
    evolutionary changes to influence ecological dynamics and vice versa, thereby
    creating a feedback between evolution and demography. The analysis of this feedback
    and the relative contributions of gene flow, demography, drift, and natural selection
    to genetic variation and differentiation has remained a recurring theme in evolutionary
    biology. Nevertheless, the effective role of these forces in maintaining variation
    and shaping patterns of diversity is not fully understood. Even in homogeneous
    environments devoid of local adaptations, such understanding remains elusive.
    Understanding this feedback is crucial, for example in determining the conditions
    under which extinction risk can be mitigated in peripheral populations subject
    to deleterious mutation accumulation at the edges of species’ ranges\r\nas well
    as in highly fragmented populations.\r\n\r\nIn this thesis we explore both uniform
    and spatially heterogeneous metapopulations, investigating and providing theoretical
    insights into the dynamics of local adaptation in the latter and examining the
    dynamics of load and extinction as well as the impact of joint ecological and
    evolutionary (eco-evolutionary) dynamics in the former. The thesis is divided
    into 5 chapters.\r\n\r\nChapter 1 provides a general introduction into the subject
    matter, clarifying concepts and ideas used throughout the thesis. In chapter 2,
    we explore how fast a species distributed across a heterogeneous landscape adapts
    to changing conditions marked by alterations in carrying capacity, selection pressure,
    and migration rate.\r\n\r\nIn chapter 3, we investigate how migration selection
    and drift influences adaptation and the maintenance of variation in a metapopulation
    with three habitats, an extension of previous models of adaptation in two habitats.
    We further develop analytical approximations for the critical threshold required
    for polymorphism to persist.\r\n\r\nThe focus of chapter 4 of the thesis is on
    understanding the interplay between ecology and evolution as coupled processes.
    We investigate how eco-evolutionary feedback between migration, selection, drift,
    and demography influences eco-evolutionary outcomes in marginal populations subject
    to deleterious mutation accumulation. Using simulations as well as theoretical
    approximations of the coupled dynamics of population size and allele frequency,
    we analyze how gene flow from a large mainland source influences genetic load
    and population size on an island (i.e., in a marginal population) under genetically
    realistic assumptions. Analyses of this sort are important because small isolated
    populations, are repeatedly affected by complex interactions between ecological
    and evolutionary processes, which can lead to their death. Understanding these
    interactions can therefore provide an insight into the conditions under which
    extinction risk can be mitigated in peripheral populations thus, contributing
    to conservation and restoration efforts.\r\n\r\nChapter 5 extends the analysis
    in chapter 4 to consider the dynamics of load (due to deleterious mutation accumulation)
    and extinction risk in a metapopulation. We explore the role of gene flow, selection,
    and dominance on load and extinction risk and further pinpoint critical thresholds
    required for metapopulation persistence.\r\n\r\nOverall this research contributes
    to our understanding of ecological and evolutionary mechanisms that shape species’
    persistence in fragmented landscapes, a crucial foundation for successful conservation
    efforts and biodiversity management."
acknowledged_ssus:
- _id: SSU
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Oluwafunmilola O
  full_name: Olusanya, Oluwafunmilola O
  id: 41AD96DC-F248-11E8-B48F-1D18A9856A87
  last_name: Olusanya
  orcid: 0000-0003-1971-8314
date_created: 2023-12-26T22:49:53Z
date_published: 2024-01-19T00:00:00Z
date_updated: 2025-05-26T09:05:10Z
day: '19'
ddc:
- '576'
degree_awarded: MS
department:
- _id: NiBa
- _id: GradSch
doi: 10.15479/at:ista:14711
ec_funded: 1
file:
- access_level: closed
  checksum: de179b1c6758f182ff0c70d8b38c1501
  content_type: application/zip
  creator: oolusany
  date_created: 2024-01-03T18:30:13Z
  date_updated: 2024-01-03T18:30:13Z
  file_id: '14730'
  file_name: FinalSubmission_Thesis_OLUSANYA.zip
  file_size: 16986244
  relation: source_file
- access_level: open_access
  checksum: 0e331585e3cd4823320aab4e69e64ccf
  content_type: application/pdf
  creator: oolusany
  date_created: 2024-01-03T18:31:34Z
  date_updated: 2024-01-03T18:31:34Z
  file_id: '14731'
  file_name: FinalSubmission2_Thesis_OLUSANYA.pdf
  file_size: 6460403
  relation: main_file
  success: 1
file_date_updated: 2024-01-03T18:31:34Z
has_accepted_license: '1'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-sa/4.0/
month: '01'
oa: 1
oa_version: Published Version
page: '183'
project:
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '665385'
  name: International IST Doctoral Program
- _id: c08d3278-5a5b-11eb-8a69-fdb09b55f4b8
  grant_number: P32896
  name: Causes and consequences of population fragmentation
- _id: 34c872fe-11ca-11ed-8bc3-8534b82131e6
  grant_number: '26380'
  name: Polygenic Adaptation in a Metapopulation
publication_identifier:
  issn:
  - 2663 - 337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '10658'
    relation: part_of_dissertation
    status: public
  - id: '10787'
    relation: part_of_dissertation
    status: public
  - id: '14732'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
- first_name: Jitka
  full_name: Polechova, Jitka
  last_name: Polechova
- first_name: Himani
  full_name: Sachdeva, Himani
  last_name: Sachdeva
title: Local adaptation, genetic load and extinction in metapopulations
tmp:
  image: /images/cc_by_nc_sa.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC
    BY-NC-SA 4.0)
  short: CC BY-NC-SA (4.0)
type: dissertation
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2024'
...
---
_id: '14769'
abstract:
- lang: eng
  text: 'For a set of points in Rd, the Euclidean k-means problems consists of finding
    k centers such that the sum of distances squared from each data point to its closest
    center is minimized. Coresets are one the main tools developed recently to solve
    this problem in a big data context. They allow to compress the initial dataset
    while preserving its structure: running any algorithm on the coreset provides
    a guarantee almost equivalent to running it on the full data. In this work, we
    study coresets in a fully-dynamic setting: points are added and deleted with the
    goal to efficiently maintain a coreset with which a k-means solution can be computed.
    Based on an algorithm from Henzinger and Kale [ESA''20], we present an efficient
    and practical implementation of a fully dynamic coreset algorithm, that improves
    the running time by up to a factor of 20 compared to our non-optimized implementation
    of the algorithm by Henzinger and Kale, without sacrificing more than 7% on the
    quality of the k-means solution.'
acknowledgement: This   project   has   received   funding   from   the   Euro-pean  Research  Council  (ERC)  under  the  EuropeanUnion’s  Horizon  2020  research  and  innovation  programme  (Grant  agreement  No.   101019564  “The  De-sign  of  Modern  Fully  Dynamic  Data  Structures  (Mo-DynStruct)”  and  the  Austrian  Science  Fund  (FWF)project
  Z 422-N, project “Static and Dynamic Hierar-chical  Graph  Decompositions”,  I  5982-N,  and  project“Fast  Algorithms  for  a  Reactive  Network  Layer  (Re-actNet)”,
  P 33775-N, with additional funding from thenetidee SCIENCE Stiftung, 2020–2024.D.  Sauplic  has  received  funding  from  the  Euro-pean  Union’s  Horizon  2020  research  and  innovation
  programme under the Marie Sklodowska-Curie    grant    agreementNo 101034413.
article_processing_charge: No
arxiv: 1
author:
- first_name: Monika H
  full_name: Henzinger, Monika H
  id: 540c9bbd-f2de-11ec-812d-d04a5be85630
  last_name: Henzinger
  orcid: 0000-0002-5008-6530
- first_name: David
  full_name: Saulpic, David
  id: f8e48cf0-b0ff-11ed-b0e9-b4c35598f964
  last_name: Saulpic
- first_name: Leonhard
  full_name: Sidl, Leonhard
  id: 8b563fd0-b441-11ee-9101-a3891c61efa6
  last_name: Sidl
citation:
  ama: 'Henzinger MH, Saulpic D, Sidl L. Experimental evaluation of fully dynamic
    k-means via coresets. In: <i>2024 Proceedings of the Symposium on Algorithm Engineering
    and Experiments</i>. Society for Industrial &#38; Applied Mathematics; 2024:220-233.
    doi:<a href="https://doi.org/10.1137/1.9781611977929.17">10.1137/1.9781611977929.17</a>'
  apa: 'Henzinger, M. H., Saulpic, D., &#38; Sidl, L. (2024). Experimental evaluation
    of fully dynamic k-means via coresets. In <i>2024 Proceedings of the Symposium
    on Algorithm Engineering and Experiments</i> (pp. 220–233). Alexandria, VA, United
    States: Society for Industrial &#38; Applied Mathematics. <a href="https://doi.org/10.1137/1.9781611977929.17">https://doi.org/10.1137/1.9781611977929.17</a>'
  chicago: Henzinger, Monika H, David Saulpic, and Leonhard Sidl. “Experimental Evaluation
    of Fully Dynamic K-Means via Coresets.” In <i>2024 Proceedings of the Symposium
    on Algorithm Engineering and Experiments</i>, 220–33. Society for Industrial &#38;
    Applied Mathematics, 2024. <a href="https://doi.org/10.1137/1.9781611977929.17">https://doi.org/10.1137/1.9781611977929.17</a>.
  ieee: M. H. Henzinger, D. Saulpic, and L. Sidl, “Experimental evaluation of fully
    dynamic k-means via coresets,” in <i>2024 Proceedings of the Symposium on Algorithm
    Engineering and Experiments</i>, Alexandria, VA, United States, 2024, pp. 220–233.
  ista: 'Henzinger MH, Saulpic D, Sidl L. 2024. Experimental evaluation of fully dynamic
    k-means via coresets. 2024 Proceedings of the Symposium on Algorithm Engineering
    and Experiments. ALENEX: Workshop on Algorithm Engineering and Experiments, 220–233.'
  mla: Henzinger, Monika H., et al. “Experimental Evaluation of Fully Dynamic K-Means
    via Coresets.” <i>2024 Proceedings of the Symposium on Algorithm Engineering and
    Experiments</i>, Society for Industrial &#38; Applied Mathematics, 2024, pp. 220–33,
    doi:<a href="https://doi.org/10.1137/1.9781611977929.17">10.1137/1.9781611977929.17</a>.
  short: M.H. Henzinger, D. Saulpic, L. Sidl, in:, 2024 Proceedings of the Symposium
    on Algorithm Engineering and Experiments, Society for Industrial &#38; Applied
    Mathematics, 2024, pp. 220–233.
conference:
  end_date: 2024-01-08
  location: Alexandria, VA, United States
  name: 'ALENEX: Workshop on Algorithm Engineering and Experiments'
  start_date: 2024-01-07
date_created: 2024-01-09T16:22:47Z
date_published: 2024-01-04T00:00:00Z
date_updated: 2025-07-15T12:51:52Z
day: '04'
department:
- _id: MoHe
doi: 10.1137/1.9781611977929.17
ec_funded: 1
external_id:
  arxiv:
  - '2310.18034'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2310.18034
month: '01'
oa: 1
oa_version: Preprint
page: 220-233
project:
- _id: bd9ca328-d553-11ed-ba76-dc4f890cfe62
  call_identifier: H2020
  grant_number: '101019564'
  name: The design and evaluation of modern fully dynamic data structures
- _id: 34def286-11ca-11ed-8bc3-da5948e1613c
  grant_number: Z00422
  name: Wittgenstein Award - Monika Henzinger
- _id: bda196b2-d553-11ed-ba76-8e8ee6c21103
  grant_number: I05982
  name: Static and Dynamic Hierarchical Graph Decompositions
- _id: bd9e3a2e-d553-11ed-ba76-8aa684ce17fe
  grant_number: 'P33775 '
  name: Fast Algorithms for a Reactive Network Layer
- _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c
  call_identifier: H2020
  grant_number: '101034413'
  name: 'IST-BRIDGE: International postdoctoral program'
publication: 2024 Proceedings of the Symposium on Algorithm Engineering and Experiments
publication_identifier:
  eisbn:
  - '9781611977929'
publication_status: published
publisher: Society for Industrial & Applied Mathematics
quality_controlled: '1'
scopus_import: '1'
status: public
title: Experimental evaluation of fully dynamic k-means via coresets
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2024'
...
