---
_id: '5436'
abstract:
- lang: eng
  text: "Recently there has been a significant effort to handle quantitative properties
    in formal verification and synthesis. While weighted automata over finite and
    infinite words provide a natural and flexible framework to express quantitative
    properties, perhaps surprisingly, some basic system properties such as average
    response time cannot be expressed using weighted automata, nor in any other know
    decidable formalism. In this work, we introduce nested weighted automata as a
    natural extension of weighted automata which makes it possible to express important
    quantitative properties such as average response time.\r\nIn nested weighted automata,
    a master automaton spins off and collects results from weighted slave automata,
    each of which computes a quantity along a finite portion of an infinite word.
    Nested weighted automata can be viewed as the quantitative analogue of monitor
    automata, which are used in run-time verification. We establish an almost complete
    decidability picture for the basic decision problems about nested weighted automata,
    and illustrate their applicability in several domains. In particular, nested weighted
    automata can be used to decide average response time properties."
alternative_title:
- IST Austria Technical Report
author:
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000−0002−2985−7724
- first_name: Jan
  full_name: Otop, Jan
  id: 2FC5DA74-F248-11E8-B48F-1D18A9856A87
  last_name: Otop
citation:
  ama: Chatterjee K, Henzinger TA, Otop J. <i>Nested Weighted Automata</i>. IST Austria;
    2015. doi:<a href="https://doi.org/10.15479/AT:IST-2015-170-v2-2">10.15479/AT:IST-2015-170-v2-2</a>
  apa: Chatterjee, K., Henzinger, T. A., &#38; Otop, J. (2015). <i>Nested weighted
    automata</i>. IST Austria. <a href="https://doi.org/10.15479/AT:IST-2015-170-v2-2">https://doi.org/10.15479/AT:IST-2015-170-v2-2</a>
  chicago: Chatterjee, Krishnendu, Thomas A Henzinger, and Jan Otop. <i>Nested Weighted
    Automata</i>. IST Austria, 2015. <a href="https://doi.org/10.15479/AT:IST-2015-170-v2-2">https://doi.org/10.15479/AT:IST-2015-170-v2-2</a>.
  ieee: K. Chatterjee, T. A. Henzinger, and J. Otop, <i>Nested weighted automata</i>.
    IST Austria, 2015.
  ista: Chatterjee K, Henzinger TA, Otop J. 2015. Nested weighted automata, IST Austria,
    29p.
  mla: Chatterjee, Krishnendu, et al. <i>Nested Weighted Automata</i>. IST Austria,
    2015, doi:<a href="https://doi.org/10.15479/AT:IST-2015-170-v2-2">10.15479/AT:IST-2015-170-v2-2</a>.
  short: K. Chatterjee, T.A. Henzinger, J. Otop, Nested Weighted Automata, IST Austria,
    2015.
date_created: 2018-12-12T11:39:19Z
date_published: 2015-04-24T00:00:00Z
date_updated: 2023-02-23T12:25:21Z
day: '24'
ddc:
- '000'
department:
- _id: KrCh
- _id: ToHe
doi: 10.15479/AT:IST-2015-170-v2-2
file:
- access_level: open_access
  checksum: 3c402f47d3669c28d04d1af405a08e3f
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T11:54:19Z
  date_updated: 2020-07-14T12:46:54Z
  file_id: '5541'
  file_name: IST-2015-170-v2+2_report.pdf
  file_size: 569991
  relation: main_file
file_date_updated: 2020-07-14T12:46:54Z
has_accepted_license: '1'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
page: '29'
publication_identifier:
  issn:
  - 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '331'
related_material:
  record:
  - id: '1656'
    relation: later_version
    status: public
  - id: '467'
    relation: later_version
    status: public
  - id: '5415'
    relation: earlier_version
    status: public
status: public
title: Nested weighted automata
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2015'
...
---
_id: '5437'
abstract:
- lang: eng
  text: "We consider the core algorithmic problems related to verification of systems
    with respect to three classical quantitative properties, namely, the mean-payoff
    property, the ratio property, and the minimum initial credit for energy property.
    \r\nThe algorithmic problem given a graph and a quantitative property asks to
    compute the optimal value (the infimum value over all traces) from every node
    of the graph. We consider graphs with constant treewidth, and it is well-known
    that the control-flow graphs of most programs have constant treewidth. Let $n$
    denote the number of nodes of a graph, $m$ the number of edges (for constant treewidth
    graphs $m=O(n)$) and $W$ the largest absolute value of the weights.\r\nOur main
    theoretical results are as follows.\r\nFirst, for constant treewidth graphs we
    present an algorithm that approximates the mean-payoff value within a multiplicative
    factor of $\\epsilon$ in time $O(n \\cdot \\log (n/\\epsilon))$ and linear space,
    as compared to the classical algorithms that require quadratic time. Second, for
    the ratio property we present an algorithm that for constant treewidth graphs
    works in time $O(n \\cdot \\log (|a\\cdot b|))=O(n\\cdot\\log (n\\cdot W))$, when
    the output is $\\frac{a}{b}$, as compared to the previously best known algorithm
    with running time $O(n^2 \\cdot \\log (n\\cdot W))$. Third, for the minimum initial
    credit problem we show that (i)~for general graphs the problem can be solved in
    $O(n^2\\cdot m)$ time and the associated decision problem can be solved in $O(n\\cdot
    m)$ time, improving the previous known $O(n^3\\cdot m\\cdot \\log (n\\cdot W))$
    and $O(n^2 \\cdot m)$ bounds, respectively; and (ii)~for constant treewidth graphs
    we present an algorithm that requires $O(n\\cdot \\log n)$ time, improving the
    previous known $O(n^4 \\cdot \\log (n \\cdot W))$ bound.\r\nWe have implemented
    some of our algorithms and show that they present a significant speedup on standard
    benchmarks. "
alternative_title:
- IST Austria Technical Report
author:
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Rasmus
  full_name: Ibsen-Jensen, Rasmus
  id: 3B699956-F248-11E8-B48F-1D18A9856A87
  last_name: Ibsen-Jensen
  orcid: 0000-0003-4783-0389
- first_name: Andreas
  full_name: Pavlogiannis, Andreas
  id: 49704004-F248-11E8-B48F-1D18A9856A87
  last_name: Pavlogiannis
  orcid: 0000-0002-8943-0722
citation:
  ama: Chatterjee K, Ibsen-Jensen R, Pavlogiannis A. <i>Faster Algorithms for Quantitative
    Verification in Constant Treewidth Graphs</i>. IST Austria; 2015. doi:<a href="https://doi.org/10.15479/AT:IST-2015-330-v2-1">10.15479/AT:IST-2015-330-v2-1</a>
  apa: Chatterjee, K., Ibsen-Jensen, R., &#38; Pavlogiannis, A. (2015). <i>Faster
    algorithms for quantitative verification in constant treewidth graphs</i>. IST
    Austria. <a href="https://doi.org/10.15479/AT:IST-2015-330-v2-1">https://doi.org/10.15479/AT:IST-2015-330-v2-1</a>
  chicago: Chatterjee, Krishnendu, Rasmus Ibsen-Jensen, and Andreas Pavlogiannis.
    <i>Faster Algorithms for Quantitative Verification in Constant Treewidth Graphs</i>.
    IST Austria, 2015. <a href="https://doi.org/10.15479/AT:IST-2015-330-v2-1">https://doi.org/10.15479/AT:IST-2015-330-v2-1</a>.
  ieee: K. Chatterjee, R. Ibsen-Jensen, and A. Pavlogiannis, <i>Faster algorithms
    for quantitative verification in constant treewidth graphs</i>. IST Austria, 2015.
  ista: Chatterjee K, Ibsen-Jensen R, Pavlogiannis A. 2015. Faster algorithms for
    quantitative verification in constant treewidth graphs, IST Austria, 27p.
  mla: Chatterjee, Krishnendu, et al. <i>Faster Algorithms for Quantitative Verification
    in Constant Treewidth Graphs</i>. IST Austria, 2015, doi:<a href="https://doi.org/10.15479/AT:IST-2015-330-v2-1">10.15479/AT:IST-2015-330-v2-1</a>.
  short: K. Chatterjee, R. Ibsen-Jensen, A. Pavlogiannis, Faster Algorithms for Quantitative
    Verification in Constant Treewidth Graphs, IST Austria, 2015.
date_created: 2018-12-12T11:39:19Z
date_published: 2015-04-27T00:00:00Z
date_updated: 2023-02-23T12:26:05Z
day: '27'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.15479/AT:IST-2015-330-v2-1
file:
- access_level: open_access
  checksum: f5917c20f84018b362d385c000a2e123
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T11:53:12Z
  date_updated: 2020-07-14T12:46:54Z
  file_id: '5473'
  file_name: IST-2015-330-v2+1_main.pdf
  file_size: 1072137
  relation: main_file
file_date_updated: 2020-07-14T12:46:54Z
has_accepted_license: '1'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
page: '27'
publication_identifier:
  issn:
  - 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '333'
related_material:
  record:
  - id: '1607'
    relation: later_version
    status: public
  - id: '5430'
    relation: earlier_version
    status: public
status: public
title: Faster algorithms for quantitative verification in constant treewidth graphs
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2015'
...
---
_id: '5438'
abstract:
- lang: eng
  text: "The edit distance between two words w1, w2 is the minimal number of word
    operations (letter insertions, deletions, and substitutions) necessary to transform
    w1 to w2. The edit distance generalizes to languages L1, L2, where the edit distance
    is the minimal number k such that for every word from L1 there exists a word in
    L2 with edit distance at most k. We study the edit distance computation problem
    between pushdown automata and their subclasses.\r\nThe problem of computing edit
    distance to a pushdown automaton is undecidable, and in practice, the interesting
    question is to compute the edit distance from a pushdown automaton (the implementation,
    a standard model for programs with recursion) to a regular language (the specification).
    In this work, we present a complete picture of decidability and complexity for
    deciding whether, for a given threshold k, the edit distance from a pushdown automaton
    to a finite automaton is at most k. "
alternative_title:
- IST Austria Technical Report
author:
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000−0002−2985−7724
- first_name: Rasmus
  full_name: Ibsen-Jensen, Rasmus
  id: 3B699956-F248-11E8-B48F-1D18A9856A87
  last_name: Ibsen-Jensen
  orcid: 0000-0003-4783-0389
- first_name: Jan
  full_name: Otop, Jan
  id: 2FC5DA74-F248-11E8-B48F-1D18A9856A87
  last_name: Otop
citation:
  ama: Chatterjee K, Henzinger TA, Ibsen-Jensen R, Otop J. <i>Edit Distance for Pushdown
    Automata</i>. IST Austria; 2015. doi:<a href="https://doi.org/10.15479/AT:IST-2015-334-v1-1">10.15479/AT:IST-2015-334-v1-1</a>
  apa: Chatterjee, K., Henzinger, T. A., Ibsen-Jensen, R., &#38; Otop, J. (2015).
    <i>Edit distance for pushdown automata</i>. IST Austria. <a href="https://doi.org/10.15479/AT:IST-2015-334-v1-1">https://doi.org/10.15479/AT:IST-2015-334-v1-1</a>
  chicago: Chatterjee, Krishnendu, Thomas A Henzinger, Rasmus Ibsen-Jensen, and Jan
    Otop. <i>Edit Distance for Pushdown Automata</i>. IST Austria, 2015. <a href="https://doi.org/10.15479/AT:IST-2015-334-v1-1">https://doi.org/10.15479/AT:IST-2015-334-v1-1</a>.
  ieee: K. Chatterjee, T. A. Henzinger, R. Ibsen-Jensen, and J. Otop, <i>Edit distance
    for pushdown automata</i>. IST Austria, 2015.
  ista: Chatterjee K, Henzinger TA, Ibsen-Jensen R, Otop J. 2015. Edit distance for
    pushdown automata, IST Austria, 15p.
  mla: Chatterjee, Krishnendu, et al. <i>Edit Distance for Pushdown Automata</i>.
    IST Austria, 2015, doi:<a href="https://doi.org/10.15479/AT:IST-2015-334-v1-1">10.15479/AT:IST-2015-334-v1-1</a>.
  short: K. Chatterjee, T.A. Henzinger, R. Ibsen-Jensen, J. Otop, Edit Distance for
    Pushdown Automata, IST Austria, 2015.
date_created: 2018-12-12T11:39:20Z
date_published: 2015-05-05T00:00:00Z
date_updated: 2023-02-23T12:20:08Z
day: '05'
ddc:
- '004'
department:
- _id: KrCh
doi: 10.15479/AT:IST-2015-334-v1-1
file:
- access_level: open_access
  checksum: 8a5f2d77560e552af87eb1982437a43b
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T11:53:56Z
  date_updated: 2020-07-14T12:46:55Z
  file_id: '5518'
  file_name: IST-2015-334-v1+1_report.pdf
  file_size: 422573
  relation: main_file
file_date_updated: 2020-07-14T12:46:55Z
has_accepted_license: '1'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
page: '15'
publication_identifier:
  issn:
  - 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '334'
related_material:
  record:
  - id: '1610'
    relation: later_version
    status: public
  - id: '465'
    relation: later_version
    status: public
status: public
title: Edit distance for pushdown automata
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2015'
...
---
_id: '5439'
abstract:
- lang: eng
  text: 'The target discounted-sum problem is the following: Given a rational discount
    factor 0 < λ < 1 and three rational values a, b, and t, does there exist a finite
    or an infinite sequence w ε(a, b)∗ or w ε(a, b)w, such that Σ|w| i=0 w(i)λi equals
    t? The problem turns out to relate to many fields of mathematics and computer
    science, and its decidability question is surprisingly hard to solve. We solve
    the finite version of the problem, and show the hardness of the infinite version,
    linking it to various areas and open problems in mathematics and computer science:
    β-expansions, discounted-sum automata, piecewise affine maps, and generalizations
    of the Cantor set. We provide some partial results to the infinite version, among
    which are solutions to its restriction to eventually-periodic sequences and to
    the cases that λ λ 1/2 or λ = 1/n, for every n ε N. We use our results for solving
    some open problems on discounted-sum automata, among which are the exact-value
    problem for nondeterministic automata over finite words and the universality and
    inclusion problems for functional automata. '
alternative_title:
- IST Austria Technical Report
author:
- first_name: Udi
  full_name: Boker, Udi
  id: 31E297B6-F248-11E8-B48F-1D18A9856A87
  last_name: Boker
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000−0002−2985−7724
- first_name: Jan
  full_name: Otop, Jan
  id: 2FC5DA74-F248-11E8-B48F-1D18A9856A87
  last_name: Otop
citation:
  ama: Boker U, Henzinger TA, Otop J. <i>The Target Discounted-Sum Problem</i>. IST
    Austria; 2015. doi:<a href="https://doi.org/10.15479/AT:IST-2015-335-v1-1">10.15479/AT:IST-2015-335-v1-1</a>
  apa: Boker, U., Henzinger, T. A., &#38; Otop, J. (2015). <i>The target discounted-sum
    problem</i>. IST Austria. <a href="https://doi.org/10.15479/AT:IST-2015-335-v1-1">https://doi.org/10.15479/AT:IST-2015-335-v1-1</a>
  chicago: Boker, Udi, Thomas A Henzinger, and Jan Otop. <i>The Target Discounted-Sum
    Problem</i>. IST Austria, 2015. <a href="https://doi.org/10.15479/AT:IST-2015-335-v1-1">https://doi.org/10.15479/AT:IST-2015-335-v1-1</a>.
  ieee: U. Boker, T. A. Henzinger, and J. Otop, <i>The target discounted-sum problem</i>.
    IST Austria, 2015.
  ista: Boker U, Henzinger TA, Otop J. 2015. The target discounted-sum problem, IST
    Austria, 20p.
  mla: Boker, Udi, et al. <i>The Target Discounted-Sum Problem</i>. IST Austria, 2015,
    doi:<a href="https://doi.org/10.15479/AT:IST-2015-335-v1-1">10.15479/AT:IST-2015-335-v1-1</a>.
  short: U. Boker, T.A. Henzinger, J. Otop, The Target Discounted-Sum Problem, IST
    Austria, 2015.
date_created: 2018-12-12T11:39:20Z
date_published: 2015-05-18T00:00:00Z
date_updated: 2023-02-23T10:08:48Z
day: '18'
ddc:
- '004'
- '512'
- '513'
department:
- _id: ToHe
doi: 10.15479/AT:IST-2015-335-v1-1
file:
- access_level: open_access
  checksum: 40405907aa012acece1bc26cf0be554d
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T11:53:55Z
  date_updated: 2020-07-14T12:46:55Z
  file_id: '5517'
  file_name: IST-2015-335-v1+1_report.pdf
  file_size: 589619
  relation: main_file
file_date_updated: 2020-07-14T12:46:55Z
has_accepted_license: '1'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Published Version
page: '20'
publication_identifier:
  issn:
  - 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '335'
related_material:
  record:
  - id: '1659'
    relation: later_version
    status: public
status: public
title: The target discounted-sum problem
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2015'
...
---
_id: '5440'
abstract:
- lang: eng
  text: 'Evolution occurs in populations of reproducing individuals. The structure
    of the population affects the outcome of the evolutionary process. Evolutionary
    graph theory is a powerful approach to study this phenomenon. There are two graphs.
    The interaction graph specifies who interacts with whom for payoff in the context
    of evolution. The replacement graph specifies who competes with whom for reproduction.
    The vertices of the two graphs are the same, and each vertex corresponds to an
    individual of the population. The fitness (or the reproductive rate) is a non-negative
    number, and depends on the payoff. A key quantity is the fixation probability
    of a new mutant. It is defined as the probability that a newly introduced mutant
    (on a single vertex) generates a lineage of offspring which eventually takes over
    the entire population of resident individuals. The basic computational questions
    are as follows: (i) the qualitative question asks whether the fixation probability
    is positive; and (ii) the quantitative approximation question asks for an approximation
    of the fixation probability. Our main results are as follows: First, we consider
    a special case of the general problem, where the residents do not reproduce. We
    show that the qualitative question is NP-complete, and the quantitative approximation
    question is #P-complete, and the hardness results hold even in the special case
    where the interaction and the replacement graphs coincide. Second, we show that
    in general both the qualitative and the quantitative approximation questions are
    PSPACE-complete. The PSPACE-hardness result for quantitative approximation holds
    even when the fitness is always positive.'
alternative_title:
- IST Austria Technical Report
author:
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Rasmus
  full_name: Ibsen-Jensen, Rasmus
  id: 3B699956-F248-11E8-B48F-1D18A9856A87
  last_name: Ibsen-Jensen
  orcid: 0000-0003-4783-0389
- first_name: Martin
  full_name: Nowak, Martin
  last_name: Nowak
citation:
  ama: Chatterjee K, Ibsen-Jensen R, Nowak M. <i>The Complexity of Evolutionary Games
    on Graphs</i>. IST Austria; 2015. doi:<a href="https://doi.org/10.15479/AT:IST-2015-323-v2-2">10.15479/AT:IST-2015-323-v2-2</a>
  apa: Chatterjee, K., Ibsen-Jensen, R., &#38; Nowak, M. (2015). <i>The complexity
    of evolutionary games on graphs</i>. IST Austria. <a href="https://doi.org/10.15479/AT:IST-2015-323-v2-2">https://doi.org/10.15479/AT:IST-2015-323-v2-2</a>
  chicago: Chatterjee, Krishnendu, Rasmus Ibsen-Jensen, and Martin Nowak. <i>The Complexity
    of Evolutionary Games on Graphs</i>. IST Austria, 2015. <a href="https://doi.org/10.15479/AT:IST-2015-323-v2-2">https://doi.org/10.15479/AT:IST-2015-323-v2-2</a>.
  ieee: K. Chatterjee, R. Ibsen-Jensen, and M. Nowak, <i>The complexity of evolutionary
    games on graphs</i>. IST Austria, 2015.
  ista: Chatterjee K, Ibsen-Jensen R, Nowak M. 2015. The complexity of evolutionary
    games on graphs, IST Austria, 18p.
  mla: Chatterjee, Krishnendu, et al. <i>The Complexity of Evolutionary Games on Graphs</i>.
    IST Austria, 2015, doi:<a href="https://doi.org/10.15479/AT:IST-2015-323-v2-2">10.15479/AT:IST-2015-323-v2-2</a>.
  short: K. Chatterjee, R. Ibsen-Jensen, M. Nowak, The Complexity of Evolutionary
    Games on Graphs, IST Austria, 2015.
date_created: 2018-12-12T11:39:21Z
date_published: 2015-06-16T00:00:00Z
date_updated: 2023-02-23T12:26:10Z
day: '16'
ddc:
- '005'
- '576'
department:
- _id: KrCh
doi: 10.15479/AT:IST-2015-323-v2-2
file:
- access_level: open_access
  checksum: 66aace7d367032af97c15e35c9be9636
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T11:53:23Z
  date_updated: 2020-07-14T12:46:56Z
  file_id: '5484'
  file_name: IST-2015-323-v2+2_main.pdf
  file_size: 466161
  relation: main_file
file_date_updated: 2020-07-14T12:46:56Z
has_accepted_license: '1'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
page: '18'
publication_identifier:
  issn:
  - 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '338'
related_material:
  record:
  - id: '5421'
    relation: earlier_version
    status: public
  - id: '5432'
    relation: earlier_version
    status: public
status: public
title: The complexity of evolutionary games on graphs
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2015'
...
---
_id: '5441'
abstract:
- lang: eng
  text: We study algorithmic questions for concurrent systems where the transitions
    are labeled from a complete, closed semiring, and path properties are algebraic
    with semiring operations. The algebraic path properties can model dataflow analysis
    problems, the shortest path problem, and many other natural problems that arise
    in program analysis. We consider that each component of the concurrent system
    is a graph with constant treewidth, a property satisfied by the controlflow graphs
    of most programs. We allow for multiple possible queries, which arise naturally
    in demand driven dataflow analysis. The study of multiple queries allows us to
    consider the tradeoff between the resource usage of the one-time preprocessing
    and for each individual query. The traditional approach constructs the product
    graph of all components and applies the best-known graph algorithm on the product.
    In this approach, even the answer to a single query requires the transitive closure
    (i.e., the results of all possible queries), which provides no room for tradeoff
    between preprocessing and query time. Our main contributions are algorithms that
    significantly improve the worst-case running time of the traditional approach,
    and provide various tradeoffs depending on the number of queries. For example,
    in a concurrent system of two components, the traditional approach requires hexic
    time in the worst case for answering one query as well as computing the transitive
    closure, whereas we show that with one-time preprocessing in almost cubic time,
    each subsequent query can be answered in at most linear time, and even the transitive
    closure can be computed in almost quartic time. Furthermore, we establish conditional
    optimality results showing that the worst-case running time of our algorithms
    cannot be improved without achieving major breakthroughs in graph algorithms (i.e.,
    improving the worst-case bound for the shortest path problem in general graphs).
    Preliminary experimental results show that our algorithms perform favorably on
    several benchmarks.
alternative_title:
- IST Austria Technical Report
author:
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Rasmus
  full_name: Ibsen-Jensen, Rasmus
  id: 3B699956-F248-11E8-B48F-1D18A9856A87
  last_name: Ibsen-Jensen
  orcid: 0000-0003-4783-0389
- first_name: Amir
  full_name: Goharshady, Amir
  id: 391365CE-F248-11E8-B48F-1D18A9856A87
  last_name: Goharshady
  orcid: 0000-0003-1702-6584
- first_name: Andreas
  full_name: Pavlogiannis, Andreas
  id: 49704004-F248-11E8-B48F-1D18A9856A87
  last_name: Pavlogiannis
  orcid: 0000-0002-8943-0722
citation:
  ama: Chatterjee K, Ibsen-Jensen R, Goharshady AK, Pavlogiannis A. <i>Algorithms
    for Algebraic Path Properties in Concurrent Systems of Constant Treewidth Components</i>.
    IST Austria; 2015. doi:<a href="https://doi.org/10.15479/AT:IST-2015-340-v1-1">10.15479/AT:IST-2015-340-v1-1</a>
  apa: Chatterjee, K., Ibsen-Jensen, R., Goharshady, A. K., &#38; Pavlogiannis, A.
    (2015). <i>Algorithms for algebraic path properties in concurrent systems of constant
    treewidth components</i>. IST Austria. <a href="https://doi.org/10.15479/AT:IST-2015-340-v1-1">https://doi.org/10.15479/AT:IST-2015-340-v1-1</a>
  chicago: Chatterjee, Krishnendu, Rasmus Ibsen-Jensen, Amir Kafshdar Goharshady,
    and Andreas Pavlogiannis. <i>Algorithms for Algebraic Path Properties in Concurrent
    Systems of Constant Treewidth Components</i>. IST Austria, 2015. <a href="https://doi.org/10.15479/AT:IST-2015-340-v1-1">https://doi.org/10.15479/AT:IST-2015-340-v1-1</a>.
  ieee: K. Chatterjee, R. Ibsen-Jensen, A. K. Goharshady, and A. Pavlogiannis, <i>Algorithms
    for algebraic path properties in concurrent systems of constant treewidth components</i>.
    IST Austria, 2015.
  ista: Chatterjee K, Ibsen-Jensen R, Goharshady AK, Pavlogiannis A. 2015. Algorithms
    for algebraic path properties in concurrent systems of constant treewidth components,
    IST Austria, 24p.
  mla: Chatterjee, Krishnendu, et al. <i>Algorithms for Algebraic Path Properties
    in Concurrent Systems of Constant Treewidth Components</i>. IST Austria, 2015,
    doi:<a href="https://doi.org/10.15479/AT:IST-2015-340-v1-1">10.15479/AT:IST-2015-340-v1-1</a>.
  short: K. Chatterjee, R. Ibsen-Jensen, A.K. Goharshady, A. Pavlogiannis, Algorithms
    for Algebraic Path Properties in Concurrent Systems of Constant Treewidth Components,
    IST Austria, 2015.
date_created: 2018-12-12T11:39:21Z
date_published: 2015-07-11T00:00:00Z
date_updated: 2023-09-19T14:36:19Z
day: '11'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.15479/AT:IST-2015-340-v1-1
file:
- access_level: open_access
  checksum: df383dc62c94d7b2ea639aba088a76c6
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T11:54:09Z
  date_updated: 2020-07-14T12:46:56Z
  file_id: '5531'
  file_name: IST-2015-340-v1+1_main.pdf
  file_size: 861396
  relation: main_file
file_date_updated: 2020-07-14T12:46:56Z
has_accepted_license: '1'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: '24'
publication_identifier:
  issn:
  - 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '340'
related_material:
  record:
  - id: '1437'
    relation: later_version
    status: public
  - id: '5442'
    relation: earlier_version
    status: public
  - id: '6009'
    relation: later_version
    status: public
status: public
title: Algorithms for algebraic path properties in concurrent systems of constant
  treewidth components
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2015'
...
---
_id: '5443'
abstract:
- lang: eng
  text: POMDPs are standard models for probabilistic planning problems, where an agent
    interacts with an uncertain environment. We study the problem of almost-sure reachability,
    where given a set of target states, the question is to decide whether there is
    a policy to ensure that the target set is reached with probability 1 (almost-surely).
    While in general the problem is EXPTIME-complete, in many practical cases policies
    with a small amount of memory suffice. Moreover, the existing solution to the
    problem is explicit, which first requires to construct explicitly an exponential
    reduction to a belief-support MDP. In this work, we first study the existence
    of observation-stationary strategies, which is NP-complete, and then small-memory
    strategies. We present a symbolic algorithm by an efficient encoding to SAT and
    using a SAT solver for the problem. We report experimental results demonstrating
    the scalability of our symbolic (SAT-based) approach.
alternative_title:
- IST Austria Technical Report
author:
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Martin
  full_name: Chmelik, Martin
  id: 3624234E-F248-11E8-B48F-1D18A9856A87
  last_name: Chmelik
- first_name: Jessica
  full_name: Davies, Jessica
  id: 378E0060-F248-11E8-B48F-1D18A9856A87
  last_name: Davies
citation:
  ama: Chatterjee K, Chmelik M, Davies J. <i>A Symbolic SAT-Based Algorithm for Almost-Sure
    Reachability with Small Strategies in POMDPs</i>. IST Austria; 2015. doi:<a href="https://doi.org/10.15479/AT:IST-2015-325-v2-1">10.15479/AT:IST-2015-325-v2-1</a>
  apa: Chatterjee, K., Chmelik, M., &#38; Davies, J. (2015). <i>A symbolic SAT-based
    algorithm for almost-sure reachability with small strategies in POMDPs</i>. IST
    Austria. <a href="https://doi.org/10.15479/AT:IST-2015-325-v2-1">https://doi.org/10.15479/AT:IST-2015-325-v2-1</a>
  chicago: Chatterjee, Krishnendu, Martin Chmelik, and Jessica Davies. <i>A Symbolic
    SAT-Based Algorithm for Almost-Sure Reachability with Small Strategies in POMDPs</i>.
    IST Austria, 2015. <a href="https://doi.org/10.15479/AT:IST-2015-325-v2-1">https://doi.org/10.15479/AT:IST-2015-325-v2-1</a>.
  ieee: K. Chatterjee, M. Chmelik, and J. Davies, <i>A symbolic SAT-based algorithm
    for almost-sure reachability with small strategies in POMDPs</i>. IST Austria,
    2015.
  ista: Chatterjee K, Chmelik M, Davies J. 2015. A symbolic SAT-based algorithm for
    almost-sure reachability with small strategies in POMDPs, IST Austria, 23p.
  mla: Chatterjee, Krishnendu, et al. <i>A Symbolic SAT-Based Algorithm for Almost-Sure
    Reachability with Small Strategies in POMDPs</i>. IST Austria, 2015, doi:<a href="https://doi.org/10.15479/AT:IST-2015-325-v2-1">10.15479/AT:IST-2015-325-v2-1</a>.
  short: K. Chatterjee, M. Chmelik, J. Davies, A Symbolic SAT-Based Algorithm for
    Almost-Sure Reachability with Small Strategies in POMDPs, IST Austria, 2015.
date_created: 2018-12-12T11:39:22Z
date_published: 2015-11-06T00:00:00Z
date_updated: 2023-02-21T16:24:05Z
day: '06'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.15479/AT:IST-2015-325-v2-1
file:
- access_level: open_access
  checksum: f0fa31ad8161ed655137e94012123ef9
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T11:53:05Z
  date_updated: 2020-07-14T12:46:57Z
  file_id: '5466'
  file_name: IST-2015-325-v2+1_main.pdf
  file_size: 412379
  relation: main_file
file_date_updated: 2020-07-14T12:46:57Z
has_accepted_license: '1'
language:
- iso: eng
month: '11'
oa: 1
oa_version: Published Version
page: '23'
publication_identifier:
  issn:
  - 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '362'
related_material:
  record:
  - id: '1166'
    relation: later_version
    status: public
status: public
title: A symbolic SAT-based algorithm for almost-sure reachability with small strategies
  in POMDPs
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2015'
...
---
_id: '5444'
abstract:
- lang: eng
  text: A comprehensive understanding of the clonal evolution of cancer is critical
    for understanding neoplasia. Genome-wide sequencing data enables evolutionary
    studies at unprecedented depth. However, classical phylogenetic methods often
    struggle with noisy sequencing data of impure DNA samples and fail to detect subclones
    that have different evolutionary trajectories. We have developed a tool, called
    Treeomics, that allows us to reconstruct the phylogeny of a cancer with commonly
    available sequencing technologies. Using Bayesian inference and Integer Linear
    Programming, robust phylogenies consistent with the biological processes underlying
    cancer evolution were obtained for pancreatic, ovarian, and prostate cancers.
    Furthermore, Treeomics correctly identified sequencing artifacts such as those
    resulting from low statistical power; nearly 7% of variants were misclassified
    by conventional statistical methods. These artifacts can skew phylogenies by creating
    illusory tumor heterogeneity among distinct samples. Importantly, we show that
    the evolutionary trees generated with Treeomics are mathematically optimal.
alternative_title:
- IST Austria Technical Report
author:
- first_name: Johannes
  full_name: Reiter, Johannes
  id: 4A918E98-F248-11E8-B48F-1D18A9856A87
  last_name: Reiter
  orcid: 0000-0002-0170-7353
- first_name: Alvin
  full_name: Makohon-Moore, Alvin
  last_name: Makohon-Moore
- first_name: Jeffrey
  full_name: Gerold, Jeffrey
  last_name: Gerold
- first_name: Ivana
  full_name: Bozic, Ivana
  last_name: Bozic
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Christine
  full_name: Iacobuzio-Donahue, Christine
  last_name: Iacobuzio-Donahue
- first_name: Bert
  full_name: Vogelstein, Bert
  last_name: Vogelstein
- first_name: Martin
  full_name: Nowak, Martin
  last_name: Nowak
citation:
  ama: Reiter J, Makohon-Moore A, Gerold J, et al. <i>Reconstructing Robust Phylogenies
    of Metastatic Cancers</i>. IST Austria; 2015. doi:<a href="https://doi.org/10.15479/AT:IST-2015-399-v1-1">10.15479/AT:IST-2015-399-v1-1</a>
  apa: Reiter, J., Makohon-Moore, A., Gerold, J., Bozic, I., Chatterjee, K., Iacobuzio-Donahue,
    C., … Nowak, M. (2015). <i>Reconstructing robust phylogenies of metastatic cancers</i>.
    IST Austria. <a href="https://doi.org/10.15479/AT:IST-2015-399-v1-1">https://doi.org/10.15479/AT:IST-2015-399-v1-1</a>
  chicago: Reiter, Johannes, Alvin Makohon-Moore, Jeffrey Gerold, Ivana Bozic, Krishnendu
    Chatterjee, Christine Iacobuzio-Donahue, Bert Vogelstein, and Martin Nowak. <i>Reconstructing
    Robust Phylogenies of Metastatic Cancers</i>. IST Austria, 2015. <a href="https://doi.org/10.15479/AT:IST-2015-399-v1-1">https://doi.org/10.15479/AT:IST-2015-399-v1-1</a>.
  ieee: J. Reiter <i>et al.</i>, <i>Reconstructing robust phylogenies of metastatic
    cancers</i>. IST Austria, 2015.
  ista: Reiter J, Makohon-Moore A, Gerold J, Bozic I, Chatterjee K, Iacobuzio-Donahue
    C, Vogelstein B, Nowak M. 2015. Reconstructing robust phylogenies of metastatic
    cancers, IST Austria, 25p.
  mla: Reiter, Johannes, et al. <i>Reconstructing Robust Phylogenies of Metastatic
    Cancers</i>. IST Austria, 2015, doi:<a href="https://doi.org/10.15479/AT:IST-2015-399-v1-1">10.15479/AT:IST-2015-399-v1-1</a>.
  short: J. Reiter, A. Makohon-Moore, J. Gerold, I. Bozic, K. Chatterjee, C. Iacobuzio-Donahue,
    B. Vogelstein, M. Nowak, Reconstructing Robust Phylogenies of Metastatic Cancers,
    IST Austria, 2015.
date_created: 2018-12-12T11:39:22Z
date_published: 2015-12-30T00:00:00Z
date_updated: 2020-07-14T23:05:07Z
day: '30'
ddc:
- '000'
- '576'
department:
- _id: KrCh
doi: 10.15479/AT:IST-2015-399-v1-1
file:
- access_level: open_access
  checksum: c47d33bdda06181753c0af36f16e7b5d
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T11:53:24Z
  date_updated: 2020-07-14T12:46:58Z
  file_id: '5485'
  file_name: IST-2015-399-v1+1_treeomics.pdf
  file_size: 3533200
  relation: main_file
file_date_updated: 2020-07-14T12:46:58Z
has_accepted_license: '1'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
page: '25'
publication_identifier:
  issn:
  - 2664-1690
publication_status: published
publisher: IST Austria
pubrep_id: '399'
status: public
title: Reconstructing robust phylogenies of metastatic cancers
type: technical_report
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2015'
...
---
_id: '5549'
abstract:
- lang: eng
  text: "This repository contains the experimental part of the CAV 2015 publication
    Counterexample Explanation by Learning Small Strategies in Markov Decision Processes.\r\nWe
    extended the probabilistic model checker PRISM to represent strategies of Markov
    Decision Processes as Decision Trees.\r\nThe archive contains a java executable
    version of the extended tool (prism_dectree.jar) together with a few examples
    of the PRISM benchmark library.\r\nTo execute the program, please have a look
    at the README.txt, which provides instructions and further information on the
    archive.\r\nThe archive contains scripts that (if run often enough) reproduces
    the data presented in the publication."
article_processing_charge: No
author:
- first_name: Andreas
  full_name: Fellner, Andreas
  id: 42BABFB4-F248-11E8-B48F-1D18A9856A87
  last_name: Fellner
citation:
  ama: 'Fellner A. Experimental part of CAV 2015 publication: Counterexample Explanation
    by Learning Small Strategies in Markov Decision Processes. 2015. doi:<a href="https://doi.org/10.15479/AT:ISTA:28">10.15479/AT:ISTA:28</a>'
  apa: 'Fellner, A. (2015). Experimental part of CAV 2015 publication: Counterexample
    Explanation by Learning Small Strategies in Markov Decision Processes. Institute
    of Science and Technology Austria. <a href="https://doi.org/10.15479/AT:ISTA:28">https://doi.org/10.15479/AT:ISTA:28</a>'
  chicago: 'Fellner, Andreas. “Experimental Part of CAV 2015 Publication: Counterexample
    Explanation by Learning Small Strategies in Markov Decision Processes.” Institute
    of Science and Technology Austria, 2015. <a href="https://doi.org/10.15479/AT:ISTA:28">https://doi.org/10.15479/AT:ISTA:28</a>.'
  ieee: 'A. Fellner, “Experimental part of CAV 2015 publication: Counterexample Explanation
    by Learning Small Strategies in Markov Decision Processes.” Institute of Science
    and Technology Austria, 2015.'
  ista: 'Fellner A. 2015. Experimental part of CAV 2015 publication: Counterexample
    Explanation by Learning Small Strategies in Markov Decision Processes, Institute
    of Science and Technology Austria, <a href="https://doi.org/10.15479/AT:ISTA:28">10.15479/AT:ISTA:28</a>.'
  mla: 'Fellner, Andreas. <i>Experimental Part of CAV 2015 Publication: Counterexample
    Explanation by Learning Small Strategies in Markov Decision Processes</i>. Institute
    of Science and Technology Austria, 2015, doi:<a href="https://doi.org/10.15479/AT:ISTA:28">10.15479/AT:ISTA:28</a>.'
  short: A. Fellner, (2015).
contributor:
- first_name: Jan
  id: 44CEF464-F248-11E8-B48F-1D18A9856A87
  last_name: Kretinsky
datarep_id: '28'
date_created: 2018-12-12T12:31:29Z
date_published: 2015-08-13T00:00:00Z
date_updated: 2024-02-21T13:52:07Z
day: '13'
ddc:
- '004'
department:
- _id: KrCh
- _id: ToHe
doi: 10.15479/AT:ISTA:28
ec_funded: 1
file:
- access_level: open_access
  checksum: b8bcb43c0893023cda66c1b69c16ac62
  content_type: application/zip
  creator: system
  date_created: 2018-12-12T13:02:31Z
  date_updated: 2020-07-14T12:47:00Z
  file_id: '5597'
  file_name: IST-2015-28-v1+2_Fellner_DataRep.zip
  file_size: 49557109
  relation: main_file
file_date_updated: 2020-07-14T12:47:00Z
has_accepted_license: '1'
keyword:
- Markov Decision Process
- Decision Tree
- Probabilistic Verification
- Counterexample Explanation
license: https://creativecommons.org/publicdomain/zero/1.0/
month: '08'
oa: 1
oa_version: Published Version
project:
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '279307'
  name: 'Quantitative Graph Games: Theory and Applications'
- _id: 25832EC2-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: S 11407_N23
  name: Rigorous Systems Engineering
publisher: Institute of Science and Technology Austria
publist_id: '5564'
related_material:
  record:
  - id: '1603'
    relation: popular_science
    status: public
status: public
title: 'Experimental part of CAV 2015 publication: Counterexample Explanation by Learning
  Small Strategies in Markov Decision Processes'
tmp:
  image: /images/cc_0.png
  legal_code_url: https://creativecommons.org/publicdomain/zero/1.0/legalcode
  name: Creative Commons Public Domain Dedication (CC0 1.0)
  short: CC0 (1.0)
type: research_data
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2015'
...
---
_id: '10794'
abstract:
- lang: eng
  text: Mathematical models are of fundamental importance in the understanding of
    complex population dynamics. For instance, they can be used to predict the population
    evolution starting from different initial conditions or to test how a system responds
    to external perturbations. For this analysis to be meaningful in real applications,
    however, it is of paramount importance to choose an appropriate model structure
    and to infer the model parameters from measured data. While many parameter inference
    methods are available for models based on deterministic ordinary differential
    equations, the same does not hold for more detailed individual-based models. Here
    we consider, in particular, stochastic models in which the time evolution of the
    species abundances is described by a continuous-time Markov chain. These models
    are governed by a master equation that is typically difficult to solve. Consequently,
    traditional inference methods that rely on iterative evaluation of parameter likelihoods
    are computationally intractable. The aim of this paper is to present recent advances
    in parameter inference for continuous-time Markov chain models, based on a moment
    closure approximation of the parameter likelihood, and to investigate how these
    results can help in understanding, and ultimately controlling, complex systems
    in ecology. Specifically, we illustrate through an agricultural pest case study
    how parameters of a stochastic individual-based model can be identified from measured
    data and how the resulting model can be used to solve an optimal control problem
    in a stochastic setting. In particular, we show how the matter of determining
    the optimal combination of two different pest control methods can be formulated
    as a chance constrained optimization problem where the control action is modeled
    as a state reset, leading to a hybrid system formulation.
acknowledgement: "The authors would like to acknowledge contributions from Baptiste
  Mottet who performed preliminary analysis regarding parameter inference for the
  considered case study in a student project (Mottet, 2014/2015).\r\nThe research
  leading to these results has received funding from the People Programme (Marie Curie
  Actions) of the European Union's Seventh Framework Programme (FP7/2007-2013) under
  REA grant agreement No. [291734] and from SystemsX under the project SignalX."
article_number: '42'
article_processing_charge: No
article_type: original
author:
- first_name: Francesca
  full_name: Parise, Francesca
  last_name: Parise
- first_name: John
  full_name: Lygeros, John
  last_name: Lygeros
- first_name: Jakob
  full_name: Ruess, Jakob
  id: 4A245D00-F248-11E8-B48F-1D18A9856A87
  last_name: Ruess
  orcid: 0000-0003-1615-3282
citation:
  ama: 'Parise F, Lygeros J, Ruess J. Bayesian inference for stochastic individual-based
    models of ecological systems: a pest control simulation study. <i>Frontiers in
    Environmental Science</i>. 2015;3. doi:<a href="https://doi.org/10.3389/fenvs.2015.00042">10.3389/fenvs.2015.00042</a>'
  apa: 'Parise, F., Lygeros, J., &#38; Ruess, J. (2015). Bayesian inference for stochastic
    individual-based models of ecological systems: a pest control simulation study.
    <i>Frontiers in Environmental Science</i>. Frontiers. <a href="https://doi.org/10.3389/fenvs.2015.00042">https://doi.org/10.3389/fenvs.2015.00042</a>'
  chicago: 'Parise, Francesca, John Lygeros, and Jakob Ruess. “Bayesian Inference
    for Stochastic Individual-Based Models of Ecological Systems: A Pest Control Simulation
    Study.” <i>Frontiers in Environmental Science</i>. Frontiers, 2015. <a href="https://doi.org/10.3389/fenvs.2015.00042">https://doi.org/10.3389/fenvs.2015.00042</a>.'
  ieee: 'F. Parise, J. Lygeros, and J. Ruess, “Bayesian inference for stochastic individual-based
    models of ecological systems: a pest control simulation study,” <i>Frontiers in
    Environmental Science</i>, vol. 3. Frontiers, 2015.'
  ista: 'Parise F, Lygeros J, Ruess J. 2015. Bayesian inference for stochastic individual-based
    models of ecological systems: a pest control simulation study. Frontiers in Environmental
    Science. 3, 42.'
  mla: 'Parise, Francesca, et al. “Bayesian Inference for Stochastic Individual-Based
    Models of Ecological Systems: A Pest Control Simulation Study.” <i>Frontiers in
    Environmental Science</i>, vol. 3, 42, Frontiers, 2015, doi:<a href="https://doi.org/10.3389/fenvs.2015.00042">10.3389/fenvs.2015.00042</a>.'
  short: F. Parise, J. Lygeros, J. Ruess, Frontiers in Environmental Science 3 (2015).
date_created: 2022-02-25T11:42:25Z
date_published: 2015-06-10T00:00:00Z
date_updated: 2022-02-25T11:59:23Z
day: '10'
ddc:
- '000'
- '570'
department:
- _id: ToHe
- _id: GaTk
doi: 10.3389/fenvs.2015.00042
ec_funded: 1
file:
- access_level: open_access
  checksum: 26c222487564e1be02a11d688d6f769d
  content_type: application/pdf
  creator: dernst
  date_created: 2022-02-25T11:55:26Z
  date_updated: 2022-02-25T11:55:26Z
  file_id: '10795'
  file_name: 2015_FrontiersEnvironmScience_Parise.pdf
  file_size: 1371201
  relation: main_file
  success: 1
file_date_updated: 2022-02-25T11:55:26Z
has_accepted_license: '1'
intvolume: '         3'
keyword:
- General Environmental Science
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '291734'
  name: International IST Postdoc Fellowship Programme
publication: Frontiers in Environmental Science
publication_identifier:
  issn:
  - 2296-665X
publication_status: published
publisher: Frontiers
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Bayesian inference for stochastic individual-based models of ecological systems:
  a pest control simulation study'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 3
year: '2015'
...
---
_id: '10796'
abstract:
- lang: eng
  text: 'We consider concurrent mean-payoff games, a very well-studied class of two-player
    (player 1 vs player 2) zero-sum games on finite-state graphs where every transition
    is assigned a reward between 0 and 1, and the payoff function is the long-run
    average of the rewards. The value is the maximal expected payoff that player 1
    can guarantee against all strategies of player 2. We consider the computation
    of the set of states with value 1 under finite-memory strategies for player 1,
    and our main results for the problem are as follows: (1) we present a polynomial-time
    algorithm; (2) we show that whenever there is a finite-memory strategy, there
    is a stationary strategy that does not need memory at all; and (3) we present
    an optimal bound (which is double exponential) on the patience of stationary strategies
    (where patience of a distribution is the inverse of the smallest positive probability
    and represents a complexity measure of a stationary strategy).'
acknowledgement: "The research was partly supported by FWF Grant No P 23499-N23, FWF
  NFN Grant\r\nNo S11407-N23 (RiSE), ERC Start grant (279307: Graph Games), and Microsoft
  faculty fellows award."
article_processing_charge: No
arxiv: 1
author:
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Rasmus
  full_name: Ibsen-Jensen, Rasmus
  id: 3B699956-F248-11E8-B48F-1D18A9856A87
  last_name: Ibsen-Jensen
  orcid: 0000-0003-4783-0389
citation:
  ama: 'Chatterjee K, Ibsen-Jensen R. The value 1 problem under finite-memory strategies
    for concurrent mean-payoff games. In: <i>Proceedings of the Twenty-Sixth Annual
    ACM-SIAM Symposium on Discrete Algorithms</i>. Vol 2015. SIAM; 2015:1018-1029.
    doi:<a href="https://doi.org/10.1137/1.9781611973730.69">10.1137/1.9781611973730.69</a>'
  apa: 'Chatterjee, K., &#38; Ibsen-Jensen, R. (2015). The value 1 problem under finite-memory
    strategies for concurrent mean-payoff games. In <i>Proceedings of the Twenty-Sixth
    Annual ACM-SIAM Symposium on Discrete Algorithms</i> (Vol. 2015, pp. 1018–1029).
    San Diego, CA, United States: SIAM. <a href="https://doi.org/10.1137/1.9781611973730.69">https://doi.org/10.1137/1.9781611973730.69</a>'
  chicago: Chatterjee, Krishnendu, and Rasmus Ibsen-Jensen. “The Value 1 Problem under
    Finite-Memory Strategies for Concurrent Mean-Payoff Games.” In <i>Proceedings
    of the Twenty-Sixth Annual ACM-SIAM Symposium on Discrete Algorithms</i>, 2015:1018–29.
    SIAM, 2015. <a href="https://doi.org/10.1137/1.9781611973730.69">https://doi.org/10.1137/1.9781611973730.69</a>.
  ieee: K. Chatterjee and R. Ibsen-Jensen, “The value 1 problem under finite-memory
    strategies for concurrent mean-payoff games,” in <i>Proceedings of the Twenty-Sixth
    Annual ACM-SIAM Symposium on Discrete Algorithms</i>, San Diego, CA, United States,
    2015, vol. 2015, no. 1, pp. 1018–1029.
  ista: 'Chatterjee K, Ibsen-Jensen R. 2015. The value 1 problem under finite-memory
    strategies for concurrent mean-payoff games. Proceedings of the Twenty-Sixth Annual
    ACM-SIAM Symposium on Discrete Algorithms. SODA: Symposium on Discrete Algorithms
    vol. 2015, 1018–1029.'
  mla: Chatterjee, Krishnendu, and Rasmus Ibsen-Jensen. “The Value 1 Problem under
    Finite-Memory Strategies for Concurrent Mean-Payoff Games.” <i>Proceedings of
    the Twenty-Sixth Annual ACM-SIAM Symposium on Discrete Algorithms</i>, vol. 2015,
    no. 1, SIAM, 2015, pp. 1018–29, doi:<a href="https://doi.org/10.1137/1.9781611973730.69">10.1137/1.9781611973730.69</a>.
  short: K. Chatterjee, R. Ibsen-Jensen, in:, Proceedings of the Twenty-Sixth Annual
    ACM-SIAM Symposium on Discrete Algorithms, SIAM, 2015, pp. 1018–1029.
conference:
  end_date: 2015-01-06
  location: San Diego, CA, United States
  name: 'SODA: Symposium on Discrete Algorithms'
  start_date: 2015-01-04
date_created: 2022-02-25T12:18:43Z
date_published: 2015-01-01T00:00:00Z
date_updated: 2022-02-25T12:33:32Z
day: '01'
department:
- _id: KrCh
doi: 10.1137/1.9781611973730.69
ec_funded: 1
external_id:
  arxiv:
  - '1409.6690'
intvolume: '      2015'
issue: '1'
language:
- iso: eng
month: '01'
oa_version: Preprint
page: 1018-1029
project:
- _id: 2584A770-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: P 23499-N23
  name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 25863FF4-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: S11407
  name: Game Theory
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '279307'
  name: 'Quantitative Graph Games: Theory and Applications'
- _id: 2587B514-B435-11E9-9278-68D0E5697425
  name: Microsoft Research Faculty Fellowship
publication: Proceedings of the Twenty-Sixth Annual ACM-SIAM Symposium on Discrete
  Algorithms
publication_identifier:
  isbn:
  - 978-161197374-7
publication_status: published
publisher: SIAM
quality_controlled: '1'
scopus_import: '1'
status: public
title: The value 1 problem under finite-memory strategies for concurrent mean-payoff
  games
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 2015
year: '2015'
...
---
_id: '9532'
abstract:
- lang: eng
  text: Genomic imprinting, an inherently epigenetic phenomenon defined by parent
    of origin-dependent gene expression, is observed in mammals and flowering plants.
    Genome-scale surveys of imprinted expression and the underlying differential epigenetic
    marks have led to the discovery of hundreds of imprinted plant genes and confirmed
    DNA and histone methylation as key regulators of plant imprinting. However, the
    biological roles of the vast majority of imprinted plant genes are unknown, and
    the evolutionary forces shaping plant imprinting remain rather opaque. Here, we
    review the mechanisms of plant genomic imprinting and discuss theories of imprinting
    evolution and biological significance in light of recent findings.
article_processing_charge: No
article_type: review
author:
- first_name: Jessica A.
  full_name: Rodrigues, Jessica A.
  last_name: Rodrigues
- first_name: Daniel
  full_name: Zilberman, Daniel
  id: 6973db13-dd5f-11ea-814e-b3e5455e9ed1
  last_name: Zilberman
  orcid: 0000-0002-0123-8649
citation:
  ama: Rodrigues JA, Zilberman D. Evolution and function of genomic imprinting in
    plants. <i>Genes and Development</i>. 2015;29(24):2517–2531. doi:<a href="https://doi.org/10.1101/gad.269902.115">10.1101/gad.269902.115</a>
  apa: Rodrigues, J. A., &#38; Zilberman, D. (2015). Evolution and function of genomic
    imprinting in plants. <i>Genes and Development</i>. Cold Spring Harbor Laboratory
    Press. <a href="https://doi.org/10.1101/gad.269902.115">https://doi.org/10.1101/gad.269902.115</a>
  chicago: Rodrigues, Jessica A., and Daniel Zilberman. “Evolution and Function of
    Genomic Imprinting in Plants.” <i>Genes and Development</i>. Cold Spring Harbor
    Laboratory Press, 2015. <a href="https://doi.org/10.1101/gad.269902.115">https://doi.org/10.1101/gad.269902.115</a>.
  ieee: J. A. Rodrigues and D. Zilberman, “Evolution and function of genomic imprinting
    in plants,” <i>Genes and Development</i>, vol. 29, no. 24. Cold Spring Harbor
    Laboratory Press, pp. 2517–2531, 2015.
  ista: Rodrigues JA, Zilberman D. 2015. Evolution and function of genomic imprinting
    in plants. Genes and Development. 29(24), 2517–2531.
  mla: Rodrigues, Jessica A., and Daniel Zilberman. “Evolution and Function of Genomic
    Imprinting in Plants.” <i>Genes and Development</i>, vol. 29, no. 24, Cold Spring
    Harbor Laboratory Press, 2015, pp. 2517–2531, doi:<a href="https://doi.org/10.1101/gad.269902.115">10.1101/gad.269902.115</a>.
  short: J.A. Rodrigues, D. Zilberman, Genes and Development 29 (2015) 2517–2531.
date_created: 2021-06-08T09:56:24Z
date_published: 2015-12-15T00:00:00Z
date_updated: 2021-12-14T07:58:15Z
day: '15'
ddc:
- '570'
department:
- _id: DaZi
doi: 10.1101/gad.269902.115
extern: '1'
external_id:
  pmid:
  - '26680300'
file:
- access_level: open_access
  checksum: 086a88cfca4677646da26ed960cb02e9
  content_type: application/pdf
  creator: asandaue
  date_created: 2021-06-08T09:55:10Z
  date_updated: 2021-06-08T09:55:10Z
  file_id: '9533'
  file_name: 2015_GenesAndDevelopment_Rodrigues.pdf
  file_size: 1116846
  relation: main_file
  success: 1
file_date_updated: 2021-06-08T09:55:10Z
has_accepted_license: '1'
intvolume: '        29'
issue: '24'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc/4.0/
month: '12'
oa: 1
oa_version: Published Version
page: 2517–2531
pmid: 1
publication: Genes and Development
publication_identifier:
  eissn:
  - 1549-5477
  issn:
  - 0890-9369
publication_status: published
publisher: Cold Spring Harbor Laboratory Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Evolution and function of genomic imprinting in plants
tmp:
  image: /images/cc_by_nc.png
  legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
  short: CC BY-NC (4.0)
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 29
year: '2015'
...
---
_id: '9711'
article_processing_charge: No
author:
- first_name: Guillaume
  full_name: Chevereau, Guillaume
  id: 424D78A0-F248-11E8-B48F-1D18A9856A87
  last_name: Chevereau
- first_name: Marta
  full_name: Lukacisinova, Marta
  id: 4342E402-F248-11E8-B48F-1D18A9856A87
  last_name: Lukacisinova
  orcid: 0000-0002-2519-8004
- first_name: Tugce
  full_name: Batur, Tugce
  last_name: Batur
- first_name: Aysegul
  full_name: Guvenek, Aysegul
  last_name: Guvenek
- first_name: Dilay Hazal
  full_name: Ayhan, Dilay Hazal
  last_name: Ayhan
- first_name: Erdal
  full_name: Toprak, Erdal
  last_name: Toprak
- first_name: Mark Tobias
  full_name: Bollenbach, Mark Tobias
  id: 3E6DB97A-F248-11E8-B48F-1D18A9856A87
  last_name: Bollenbach
  orcid: 0000-0003-4398-476X
citation:
  ama: Chevereau G, Lukacisinova M, Batur T, et al. Excel file containing the raw
    data for all figures. 2015. doi:<a href="https://doi.org/10.1371/journal.pbio.1002299.s001">10.1371/journal.pbio.1002299.s001</a>
  apa: Chevereau, G., Lukacisinova, M., Batur, T., Guvenek, A., Ayhan, D. H., Toprak,
    E., &#38; Bollenbach, M. T. (2015). Excel file containing the raw data for all
    figures. Public Library of Science. <a href="https://doi.org/10.1371/journal.pbio.1002299.s001">https://doi.org/10.1371/journal.pbio.1002299.s001</a>
  chicago: Chevereau, Guillaume, Marta Lukacisinova, Tugce Batur, Aysegul Guvenek,
    Dilay Hazal Ayhan, Erdal Toprak, and Mark Tobias Bollenbach. “Excel File Containing
    the Raw Data for All Figures.” Public Library of Science, 2015. <a href="https://doi.org/10.1371/journal.pbio.1002299.s001">https://doi.org/10.1371/journal.pbio.1002299.s001</a>.
  ieee: G. Chevereau <i>et al.</i>, “Excel file containing the raw data for all figures.”
    Public Library of Science, 2015.
  ista: Chevereau G, Lukacisinova M, Batur T, Guvenek A, Ayhan DH, Toprak E, Bollenbach
    MT. 2015. Excel file containing the raw data for all figures, Public Library of
    Science, <a href="https://doi.org/10.1371/journal.pbio.1002299.s001">10.1371/journal.pbio.1002299.s001</a>.
  mla: Chevereau, Guillaume, et al. <i>Excel File Containing the Raw Data for All
    Figures</i>. Public Library of Science, 2015, doi:<a href="https://doi.org/10.1371/journal.pbio.1002299.s001">10.1371/journal.pbio.1002299.s001</a>.
  short: G. Chevereau, M. Lukacisinova, T. Batur, A. Guvenek, D.H. Ayhan, E. Toprak,
    M.T. Bollenbach, (2015).
date_created: 2021-07-23T11:53:50Z
date_published: 2015-11-18T00:00:00Z
date_updated: 2023-02-23T10:07:02Z
day: '18'
department:
- _id: ToBo
doi: 10.1371/journal.pbio.1002299.s001
month: '11'
oa_version: Published Version
publisher: Public Library of Science
related_material:
  record:
  - id: '1619'
    relation: used_in_publication
    status: public
status: public
title: Excel file containing the raw data for all figures
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2015'
...
---
_id: '9712'
article_processing_charge: No
author:
- first_name: Murat
  full_name: Tugrul, Murat
  id: 37C323C6-F248-11E8-B48F-1D18A9856A87
  last_name: Tugrul
  orcid: 0000-0002-8523-0758
- first_name: Tiago
  full_name: Paixao, Tiago
  id: 2C5658E6-F248-11E8-B48F-1D18A9856A87
  last_name: Paixao
  orcid: 0000-0003-2361-3953
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
- first_name: Gašper
  full_name: Tkačik, Gašper
  id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
  last_name: Tkačik
  orcid: 0000-0002-6699-1455
citation:
  ama: Tugrul M, Paixao T, Barton NH, Tkačik G. Other fitness models for comparison
    &#38; for interacting TFBSs. 2015. doi:<a href="https://doi.org/10.1371/journal.pgen.1005639.s001">10.1371/journal.pgen.1005639.s001</a>
  apa: Tugrul, M., Paixao, T., Barton, N. H., &#38; Tkačik, G. (2015). Other fitness
    models for comparison &#38; for interacting TFBSs. Public Library of Science.
    <a href="https://doi.org/10.1371/journal.pgen.1005639.s001">https://doi.org/10.1371/journal.pgen.1005639.s001</a>
  chicago: Tugrul, Murat, Tiago Paixao, Nicholas H Barton, and Gašper Tkačik. “Other
    Fitness Models for Comparison &#38; for Interacting TFBSs.” Public Library of
    Science, 2015. <a href="https://doi.org/10.1371/journal.pgen.1005639.s001">https://doi.org/10.1371/journal.pgen.1005639.s001</a>.
  ieee: M. Tugrul, T. Paixao, N. H. Barton, and G. Tkačik, “Other fitness models for
    comparison &#38; for interacting TFBSs.” Public Library of Science, 2015.
  ista: Tugrul M, Paixao T, Barton NH, Tkačik G. 2015. Other fitness models for comparison
    &#38; for interacting TFBSs, Public Library of Science, <a href="https://doi.org/10.1371/journal.pgen.1005639.s001">10.1371/journal.pgen.1005639.s001</a>.
  mla: Tugrul, Murat, et al. <i>Other Fitness Models for Comparison &#38; for Interacting
    TFBSs</i>. Public Library of Science, 2015, doi:<a href="https://doi.org/10.1371/journal.pgen.1005639.s001">10.1371/journal.pgen.1005639.s001</a>.
  short: M. Tugrul, T. Paixao, N.H. Barton, G. Tkačik, (2015).
date_created: 2021-07-23T12:00:37Z
date_published: 2015-11-06T00:00:00Z
date_updated: 2025-05-28T11:57:04Z
day: '06'
department:
- _id: NiBa
- _id: CaGu
- _id: GaTk
doi: 10.1371/journal.pgen.1005639.s001
month: '11'
oa_version: Published Version
publisher: Public Library of Science
related_material:
  record:
  - id: '1666'
    relation: used_in_publication
    status: public
status: public
title: Other fitness models for comparison & for interacting TFBSs
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2015'
...
---
_id: '9714'
article_processing_charge: No
author:
- first_name: Àngel
  full_name: Gómez Sicilia, Àngel
  last_name: Gómez Sicilia
- first_name: Mateusz K
  full_name: Sikora, Mateusz K
  id: 2F74BCDE-F248-11E8-B48F-1D18A9856A87
  last_name: Sikora
- first_name: Marek
  full_name: Cieplak, Marek
  last_name: Cieplak
- first_name: Mariano
  full_name: Carrión Vázquez, Mariano
  last_name: Carrión Vázquez
citation:
  ama: Gómez Sicilia À, Sikora MK, Cieplak M, Carrión Vázquez M. An exploration of
    the universe of polyglutamine structures - submission to PLOS journals. 2015.
    doi:<a href="https://doi.org/10.1371/journal.pcbi.1004541.s001">10.1371/journal.pcbi.1004541.s001</a>
  apa: Gómez Sicilia, À., Sikora, M. K., Cieplak, M., &#38; Carrión Vázquez, M. (2015).
    An exploration of the universe of polyglutamine structures - submission to PLOS
    journals. Public Library of Science . <a href="https://doi.org/10.1371/journal.pcbi.1004541.s001">https://doi.org/10.1371/journal.pcbi.1004541.s001</a>
  chicago: Gómez Sicilia, Àngel, Mateusz K Sikora, Marek Cieplak, and Mariano Carrión
    Vázquez. “An Exploration of the Universe of Polyglutamine Structures - Submission
    to PLOS Journals.” Public Library of Science , 2015. <a href="https://doi.org/10.1371/journal.pcbi.1004541.s001">https://doi.org/10.1371/journal.pcbi.1004541.s001</a>.
  ieee: À. Gómez Sicilia, M. K. Sikora, M. Cieplak, and M. Carrión Vázquez, “An exploration
    of the universe of polyglutamine structures - submission to PLOS journals.” Public
    Library of Science , 2015.
  ista: Gómez Sicilia À, Sikora MK, Cieplak M, Carrión Vázquez M. 2015. An exploration
    of the universe of polyglutamine structures - submission to PLOS journals, Public
    Library of Science , <a href="https://doi.org/10.1371/journal.pcbi.1004541.s001">10.1371/journal.pcbi.1004541.s001</a>.
  mla: Gómez Sicilia, Àngel, et al. <i>An Exploration of the Universe of Polyglutamine
    Structures - Submission to PLOS Journals</i>. Public Library of Science , 2015,
    doi:<a href="https://doi.org/10.1371/journal.pcbi.1004541.s001">10.1371/journal.pcbi.1004541.s001</a>.
  short: À. Gómez Sicilia, M.K. Sikora, M. Cieplak, M. Carrión Vázquez, (2015).
date_created: 2021-07-23T12:05:28Z
date_published: 2015-10-23T00:00:00Z
date_updated: 2023-02-23T10:04:35Z
day: '23'
department:
- _id: CaHe
doi: 10.1371/journal.pcbi.1004541.s001
month: '10'
oa_version: Published Version
publisher: 'Public Library of Science '
related_material:
  record:
  - id: '1566'
    relation: used_in_publication
    status: public
status: public
title: An exploration of the universe of polyglutamine structures - submission to
  PLOS journals
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2015'
...
---
_id: '9715'
article_processing_charge: No
author:
- first_name: Barbora
  full_name: Trubenova, Barbora
  id: 42302D54-F248-11E8-B48F-1D18A9856A87
  last_name: Trubenova
  orcid: 0000-0002-6873-2967
- first_name: Sebastian
  full_name: Novak, Sebastian
  id: 461468AE-F248-11E8-B48F-1D18A9856A87
  last_name: Novak
- first_name: Reinmar
  full_name: Hager, Reinmar
  last_name: Hager
citation:
  ama: Trubenova B, Novak S, Hager R. Mathematical inference of the results. 2015.
    doi:<a href="https://doi.org/10.1371/journal.pone.0126907.s001">10.1371/journal.pone.0126907.s001</a>
  apa: Trubenova, B., Novak, S., &#38; Hager, R. (2015). Mathematical inference of
    the results. Public Library of Science. <a href="https://doi.org/10.1371/journal.pone.0126907.s001">https://doi.org/10.1371/journal.pone.0126907.s001</a>
  chicago: Trubenova, Barbora, Sebastian Novak, and Reinmar Hager. “Mathematical Inference
    of the Results.” Public Library of Science, 2015. <a href="https://doi.org/10.1371/journal.pone.0126907.s001">https://doi.org/10.1371/journal.pone.0126907.s001</a>.
  ieee: B. Trubenova, S. Novak, and R. Hager, “Mathematical inference of the results.”
    Public Library of Science, 2015.
  ista: Trubenova B, Novak S, Hager R. 2015. Mathematical inference of the results,
    Public Library of Science, <a href="https://doi.org/10.1371/journal.pone.0126907.s001">10.1371/journal.pone.0126907.s001</a>.
  mla: Trubenova, Barbora, et al. <i>Mathematical Inference of the Results</i>. Public
    Library of Science, 2015, doi:<a href="https://doi.org/10.1371/journal.pone.0126907.s001">10.1371/journal.pone.0126907.s001</a>.
  short: B. Trubenova, S. Novak, R. Hager, (2015).
date_created: 2021-07-23T12:11:30Z
date_published: 2015-05-18T00:00:00Z
date_updated: 2023-02-23T10:15:25Z
day: '18'
department:
- _id: NiBa
doi: 10.1371/journal.pone.0126907.s001
month: '05'
oa_version: Published Version
publisher: Public Library of Science
related_material:
  record:
  - id: '1809'
    relation: used_in_publication
    status: public
status: public
title: Mathematical inference of the results
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2015'
...
---
_id: '9718'
article_processing_charge: No
author:
- first_name: Tamar
  full_name: Friedlander, Tamar
  id: 36A5845C-F248-11E8-B48F-1D18A9856A87
  last_name: Friedlander
- first_name: Avraham E.
  full_name: Mayo, Avraham E.
  last_name: Mayo
- first_name: Tsvi
  full_name: Tlusty, Tsvi
  last_name: Tlusty
- first_name: Uri
  full_name: Alon, Uri
  last_name: Alon
citation:
  ama: Friedlander T, Mayo AE, Tlusty T, Alon U. Supporting information text. 2015.
    doi:<a href="https://doi.org/10.1371/journal.pcbi.1004055.s001">10.1371/journal.pcbi.1004055.s001</a>
  apa: Friedlander, T., Mayo, A. E., Tlusty, T., &#38; Alon, U. (2015). Supporting
    information text. Public Library of Science. <a href="https://doi.org/10.1371/journal.pcbi.1004055.s001">https://doi.org/10.1371/journal.pcbi.1004055.s001</a>
  chicago: Friedlander, Tamar, Avraham E. Mayo, Tsvi Tlusty, and Uri Alon. “Supporting
    Information Text.” Public Library of Science, 2015. <a href="https://doi.org/10.1371/journal.pcbi.1004055.s001">https://doi.org/10.1371/journal.pcbi.1004055.s001</a>.
  ieee: T. Friedlander, A. E. Mayo, T. Tlusty, and U. Alon, “Supporting information
    text.” Public Library of Science, 2015.
  ista: Friedlander T, Mayo AE, Tlusty T, Alon U. 2015. Supporting information text,
    Public Library of Science, <a href="https://doi.org/10.1371/journal.pcbi.1004055.s001">10.1371/journal.pcbi.1004055.s001</a>.
  mla: Friedlander, Tamar, et al. <i>Supporting Information Text</i>. Public Library
    of Science, 2015, doi:<a href="https://doi.org/10.1371/journal.pcbi.1004055.s001">10.1371/journal.pcbi.1004055.s001</a>.
  short: T. Friedlander, A.E. Mayo, T. Tlusty, U. Alon, (2015).
date_created: 2021-07-26T08:35:23Z
date_published: 2015-03-23T00:00:00Z
date_updated: 2023-02-23T10:16:13Z
day: '23'
department:
- _id: GaTk
doi: 10.1371/journal.pcbi.1004055.s001
month: '03'
oa_version: Published Version
publisher: Public Library of Science
related_material:
  record:
  - id: '1827'
    relation: used_in_publication
    status: public
status: public
title: Supporting information text
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2015'
...
---
_id: '9719'
abstract:
- lang: eng
  text: Parasitism creates selection for resistance mechanisms in host populations
    and is hypothesized to promote increased host evolvability. However, the influence
    of these traits on host evolution when parasites are no longer present is unclear.
    We used experimental evolution and whole-genome sequencing of Escherichia coli
    to determine the effects of past and present exposure to parasitic viruses (phages)
    on the spread of mutator alleles, resistance, and bacterial competitive fitness.
    We found that mutator alleles spread rapidly during adaptation to any of four
    different phage species, and this pattern was even more pronounced with multiple
    phages present simultaneously. However, hypermutability did not detectably accelerate
    adaptation in the absence of phages and recovery of fitness costs associated with
    resistance. Several lineages evolved phage resistance through elevated mucoidy,
    and during subsequent evolution in phage-free conditions they rapidly reverted
    to nonmucoid, phage-susceptible phenotypes. Genome sequencing revealed that this
    phenotypic reversion was achieved by additional genetic changes rather than by
    genotypic reversion of the initial resistance mutations. Insertion sequence (IS)
    elements played a key role in both the acquisition of resistance and adaptation
    in the absence of parasites; unlike single nucleotide polymorphisms, IS insertions
    were not more frequent in mutator lineages. Our results provide a genetic explanation
    for rapid reversion of mucoidy, a phenotype observed in other bacterial species
    including human pathogens. Moreover, this demonstrates that the types of genetic
    change underlying adaptation to fitness costs, and consequently the impact of
    evolvability mechanisms such as increased point-mutation rates, depend critically
    on the mechanism of resistance.
article_processing_charge: No
author:
- first_name: Sébastien
  full_name: Wielgoss, Sébastien
  last_name: Wielgoss
- first_name: Tobias
  full_name: Bergmiller, Tobias
  id: 2C471CFA-F248-11E8-B48F-1D18A9856A87
  last_name: Bergmiller
  orcid: 0000-0001-5396-4346
- first_name: Anna M.
  full_name: Bischofberger, Anna M.
  last_name: Bischofberger
- first_name: Alex R.
  full_name: Hall, Alex R.
  last_name: Hall
citation:
  ama: 'Wielgoss S, Bergmiller T, Bischofberger AM, Hall AR. Data from: Adaptation
    to parasites and costs of parasite resistance in mutator and non-mutator bacteria.
    2015. doi:<a href="https://doi.org/10.5061/dryad.cj910">10.5061/dryad.cj910</a>'
  apa: 'Wielgoss, S., Bergmiller, T., Bischofberger, A. M., &#38; Hall, A. R. (2015).
    Data from: Adaptation to parasites and costs of parasite resistance in mutator
    and non-mutator bacteria. Dryad. <a href="https://doi.org/10.5061/dryad.cj910">https://doi.org/10.5061/dryad.cj910</a>'
  chicago: 'Wielgoss, Sébastien, Tobias Bergmiller, Anna M. Bischofberger, and Alex
    R. Hall. “Data from: Adaptation to Parasites and Costs of Parasite Resistance
    in Mutator and Non-Mutator Bacteria.” Dryad, 2015. <a href="https://doi.org/10.5061/dryad.cj910">https://doi.org/10.5061/dryad.cj910</a>.'
  ieee: 'S. Wielgoss, T. Bergmiller, A. M. Bischofberger, and A. R. Hall, “Data from:
    Adaptation to parasites and costs of parasite resistance in mutator and non-mutator
    bacteria.” Dryad, 2015.'
  ista: 'Wielgoss S, Bergmiller T, Bischofberger AM, Hall AR. 2015. Data from: Adaptation
    to parasites and costs of parasite resistance in mutator and non-mutator bacteria,
    Dryad, <a href="https://doi.org/10.5061/dryad.cj910">10.5061/dryad.cj910</a>.'
  mla: 'Wielgoss, Sébastien, et al. <i>Data from: Adaptation to Parasites and Costs
    of Parasite Resistance in Mutator and Non-Mutator Bacteria</i>. Dryad, 2015, doi:<a
    href="https://doi.org/10.5061/dryad.cj910">10.5061/dryad.cj910</a>.'
  short: S. Wielgoss, T. Bergmiller, A.M. Bischofberger, A.R. Hall, (2015).
date_created: 2021-07-26T08:44:04Z
date_published: 2015-12-21T00:00:00Z
date_updated: 2023-09-05T13:46:04Z
day: '21'
department:
- _id: CaGu
doi: 10.5061/dryad.cj910
main_file_link:
- open_access: '1'
  url: https://doi.org/10.5061/dryad.cj910
month: '12'
oa: 1
oa_version: Published Version
publisher: Dryad
related_material:
  record:
  - id: '5749'
    relation: used_in_publication
    status: public
status: public
title: 'Data from: Adaptation to parasites and costs of parasite resistance in mutator
  and non-mutator bacteria'
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2015'
...
---
_id: '9721'
abstract:
- lang: eng
  text: To prevent epidemics, insect societies have evolved collective disease defences
    that are highly effective at curing exposed individuals and limiting disease transmission
    to healthy group members. Grooming is an important sanitary behaviour—either performed
    towards oneself (self-grooming) or towards others (allogrooming)—to remove infectious
    agents from the body surface of exposed individuals, but at the risk of disease
    contraction by the groomer. We use garden ants (Lasius neglectus) and the fungal
    pathogen Metarhizium as a model system to study how pathogen presence affects
    self-grooming and allogrooming between exposed and healthy individuals. We develop
    an epidemiological SIS model to explore how experimentally observed grooming patterns
    affect disease spread within the colony, thereby providing a direct link between
    the expression and direction of sanitary behaviours, and their effects on colony-level
    epidemiology. We find that fungus-exposed ants increase self-grooming, while simultaneously
    decreasing allogrooming. This behavioural modulation seems universally adaptive
    and is predicted to contain disease spread in a great variety of host–pathogen
    systems. In contrast, allogrooming directed towards pathogen-exposed individuals
    might both increase and decrease disease risk. Our model reveals that the effect
    of allogrooming depends on the balance between pathogen infectiousness and efficiency
    of social host defences, which are likely to vary across host–pathogen systems.
article_processing_charge: No
author:
- first_name: Fabian
  full_name: Theis, Fabian
  last_name: Theis
- first_name: Line V
  full_name: Ugelvig, Line V
  id: 3DC97C8E-F248-11E8-B48F-1D18A9856A87
  last_name: Ugelvig
  orcid: 0000-0003-1832-8883
- first_name: Carsten
  full_name: Marr, Carsten
  last_name: Marr
- first_name: Sylvia
  full_name: Cremer, Sylvia
  id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
  last_name: Cremer
  orcid: 0000-0002-2193-3868
citation:
  ama: 'Theis F, Ugelvig LV, Marr C, Cremer S. Data from: Opposing effects of allogrooming
    on disease transmission in ant societies. 2015. doi:<a href="https://doi.org/10.5061/dryad.dj2bf">10.5061/dryad.dj2bf</a>'
  apa: 'Theis, F., Ugelvig, L. V., Marr, C., &#38; Cremer, S. (2015). Data from: Opposing
    effects of allogrooming on disease transmission in ant societies. Dryad. <a href="https://doi.org/10.5061/dryad.dj2bf">https://doi.org/10.5061/dryad.dj2bf</a>'
  chicago: 'Theis, Fabian, Line V Ugelvig, Carsten Marr, and Sylvia Cremer. “Data
    from: Opposing Effects of Allogrooming on Disease Transmission in Ant Societies.”
    Dryad, 2015. <a href="https://doi.org/10.5061/dryad.dj2bf">https://doi.org/10.5061/dryad.dj2bf</a>.'
  ieee: 'F. Theis, L. V. Ugelvig, C. Marr, and S. Cremer, “Data from: Opposing effects
    of allogrooming on disease transmission in ant societies.” Dryad, 2015.'
  ista: 'Theis F, Ugelvig LV, Marr C, Cremer S. 2015. Data from: Opposing effects
    of allogrooming on disease transmission in ant societies, Dryad, <a href="https://doi.org/10.5061/dryad.dj2bf">10.5061/dryad.dj2bf</a>.'
  mla: 'Theis, Fabian, et al. <i>Data from: Opposing Effects of Allogrooming on Disease
    Transmission in Ant Societies</i>. Dryad, 2015, doi:<a href="https://doi.org/10.5061/dryad.dj2bf">10.5061/dryad.dj2bf</a>.'
  short: F. Theis, L.V. Ugelvig, C. Marr, S. Cremer, (2015).
date_created: 2021-07-26T09:38:36Z
date_published: 2015-12-29T00:00:00Z
date_updated: 2023-02-23T10:16:22Z
day: '29'
department:
- _id: SyCr
doi: 10.5061/dryad.dj2bf
main_file_link:
- open_access: '1'
  url: https://doi.org/10.5061/dryad.dj2bf
month: '12'
oa: 1
oa_version: Published Version
publisher: Dryad
related_material:
  record:
  - id: '1830'
    relation: used_in_publication
    status: public
status: public
title: 'Data from: Opposing effects of allogrooming on disease transmission in ant
  societies'
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2015'
...
---
_id: '9737'
article_processing_charge: No
author:
- first_name: Olga
  full_name: Symonova, Olga
  id: 3C0C7BC6-F248-11E8-B48F-1D18A9856A87
  last_name: Symonova
- first_name: Christopher
  full_name: Topp, Christopher
  last_name: Topp
- first_name: Herbert
  full_name: Edelsbrunner, Herbert
  id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
  last_name: Edelsbrunner
  orcid: 0000-0002-9823-6833
citation:
  ama: Symonova O, Topp C, Edelsbrunner H. Root traits computed by DynamicRoots for
    the maize root shown in fig 2. 2015. doi:<a href="https://doi.org/10.1371/journal.pone.0127657.s001">10.1371/journal.pone.0127657.s001</a>
  apa: Symonova, O., Topp, C., &#38; Edelsbrunner, H. (2015). Root traits computed
    by DynamicRoots for the maize root shown in fig 2. Public Library of Science.
    <a href="https://doi.org/10.1371/journal.pone.0127657.s001">https://doi.org/10.1371/journal.pone.0127657.s001</a>
  chicago: Symonova, Olga, Christopher Topp, and Herbert Edelsbrunner. “Root Traits
    Computed by DynamicRoots for the Maize Root Shown in Fig 2.” Public Library of
    Science, 2015. <a href="https://doi.org/10.1371/journal.pone.0127657.s001">https://doi.org/10.1371/journal.pone.0127657.s001</a>.
  ieee: O. Symonova, C. Topp, and H. Edelsbrunner, “Root traits computed by DynamicRoots
    for the maize root shown in fig 2.” Public Library of Science, 2015.
  ista: Symonova O, Topp C, Edelsbrunner H. 2015. Root traits computed by DynamicRoots
    for the maize root shown in fig 2, Public Library of Science, <a href="https://doi.org/10.1371/journal.pone.0127657.s001">10.1371/journal.pone.0127657.s001</a>.
  mla: Symonova, Olga, et al. <i>Root Traits Computed by DynamicRoots for the Maize
    Root Shown in Fig 2</i>. Public Library of Science, 2015, doi:<a href="https://doi.org/10.1371/journal.pone.0127657.s001">10.1371/journal.pone.0127657.s001</a>.
  short: O. Symonova, C. Topp, H. Edelsbrunner, (2015).
date_created: 2021-07-28T06:20:13Z
date_published: 2015-06-01T00:00:00Z
date_updated: 2023-02-23T10:14:42Z
day: '01'
department:
- _id: MaJö
- _id: HeEd
doi: 10.1371/journal.pone.0127657.s001
month: '06'
oa_version: Published Version
publisher: Public Library of Science
related_material:
  record:
  - id: '1793'
    relation: used_in_publication
    status: public
status: public
title: Root traits computed by DynamicRoots for the maize root shown in fig 2
type: research_data_reference
user_id: 6785fbc1-c503-11eb-8a32-93094b40e1cf
year: '2015'
...
