---
_id: '571'
abstract:
- lang: eng
  text: Blood platelets are critical for hemostasis and thrombosis and play diverse
    roles during immune responses. Despite these versatile tasks in mammalian biology,
    their skills on a cellular level are deemed limited, mainly consisting in rolling,
    adhesion, and aggregate formation. Here, we identify an unappreciated asset of
    platelets and show that adherent platelets use adhesion receptors to mechanically
    probe the adhesive substrate in their local microenvironment. When actomyosin-dependent
    traction forces overcome substrate resistance, platelets migrate and pile up the
    adhesive substrate together with any bound particulate material. They use this
    ability to act as cellular scavengers, scanning the vascular surface for potential
    invaders and collecting deposited bacteria. Microbe collection by migrating platelets
    boosts the activity of professional phagocytes, exacerbating inflammatory tissue
    injury in sepsis. This assigns platelets a central role in innate immune responses
    and identifies them as potential targets to dampen inflammatory tissue damage
    in clinical scenarios of severe systemic infection. In addition to their role
    in thrombosis and hemostasis, platelets can also migrate to sites of infection
    to help trap bacteria and clear the vascular surface.
author:
- first_name: Florian R
  full_name: Gärtner, Florian R
  id: 397A88EE-F248-11E8-B48F-1D18A9856A87
  last_name: Gärtner
  orcid: 0000-0001-6120-3723
- first_name: Zerkah
  full_name: Ahmad, Zerkah
  last_name: Ahmad
- first_name: Gerhild
  full_name: Rosenberger, Gerhild
  last_name: Rosenberger
- first_name: Shuxia
  full_name: Fan, Shuxia
  last_name: Fan
- first_name: Leo
  full_name: Nicolai, Leo
  last_name: Nicolai
- first_name: Benjamin
  full_name: Busch, Benjamin
  last_name: Busch
- first_name: Gökce
  full_name: Yavuz, Gökce
  last_name: Yavuz
- first_name: Manja
  full_name: Luckner, Manja
  last_name: Luckner
- first_name: Hellen
  full_name: Ishikawa Ankerhold, Hellen
  last_name: Ishikawa Ankerhold
- first_name: Roman
  full_name: Hennel, Roman
  last_name: Hennel
- first_name: Alexandre
  full_name: Benechet, Alexandre
  last_name: Benechet
- first_name: Michael
  full_name: Lorenz, Michael
  last_name: Lorenz
- first_name: Sue
  full_name: Chandraratne, Sue
  last_name: Chandraratne
- first_name: Irene
  full_name: Schubert, Irene
  last_name: Schubert
- first_name: Sebastian
  full_name: Helmer, Sebastian
  last_name: Helmer
- first_name: Bianca
  full_name: Striednig, Bianca
  last_name: Striednig
- first_name: Konstantin
  full_name: Stark, Konstantin
  last_name: Stark
- first_name: Marek
  full_name: Janko, Marek
  last_name: Janko
- first_name: Ralph
  full_name: Böttcher, Ralph
  last_name: Böttcher
- first_name: Admar
  full_name: Verschoor, Admar
  last_name: Verschoor
- first_name: Catherine
  full_name: Leon, Catherine
  last_name: Leon
- first_name: Christian
  full_name: Gachet, Christian
  last_name: Gachet
- first_name: Thomas
  full_name: Gudermann, Thomas
  last_name: Gudermann
- first_name: Michael
  full_name: Mederos Y Schnitzler, Michael
  last_name: Mederos Y Schnitzler
- first_name: Zachary
  full_name: Pincus, Zachary
  last_name: Pincus
- first_name: Matteo
  full_name: Iannacone, Matteo
  last_name: Iannacone
- first_name: Rainer
  full_name: Haas, Rainer
  last_name: Haas
- first_name: Gerhard
  full_name: Wanner, Gerhard
  last_name: Wanner
- first_name: Kirsten
  full_name: Lauber, Kirsten
  last_name: Lauber
- first_name: Michael K
  full_name: Sixt, Michael K
  id: 41E9FBEA-F248-11E8-B48F-1D18A9856A87
  last_name: Sixt
  orcid: 0000-0002-6620-9179
- first_name: Steffen
  full_name: Massberg, Steffen
  last_name: Massberg
citation:
  ama: Gärtner FR, Ahmad Z, Rosenberger G, et al. Migrating platelets are mechano
    scavengers that collect and bundle bacteria. <i>Cell Press</i>. 2017;171(6):1368-1382.
    doi:<a href="https://doi.org/10.1016/j.cell.2017.11.001">10.1016/j.cell.2017.11.001</a>
  apa: Gärtner, F. R., Ahmad, Z., Rosenberger, G., Fan, S., Nicolai, L., Busch, B.,
    … Massberg, S. (2017). Migrating platelets are mechano scavengers that collect
    and bundle bacteria. <i>Cell Press</i>. Cell Press. <a href="https://doi.org/10.1016/j.cell.2017.11.001">https://doi.org/10.1016/j.cell.2017.11.001</a>
  chicago: Gärtner, Florian R, Zerkah Ahmad, Gerhild Rosenberger, Shuxia Fan, Leo
    Nicolai, Benjamin Busch, Gökce Yavuz, et al. “Migrating Platelets Are Mechano
    Scavengers That Collect and Bundle Bacteria.” <i>Cell Press</i>. Cell Press, 2017.
    <a href="https://doi.org/10.1016/j.cell.2017.11.001">https://doi.org/10.1016/j.cell.2017.11.001</a>.
  ieee: F. R. Gärtner <i>et al.</i>, “Migrating platelets are mechano scavengers that
    collect and bundle bacteria,” <i>Cell Press</i>, vol. 171, no. 6. Cell Press,
    pp. 1368–1382, 2017.
  ista: Gärtner FR, Ahmad Z, Rosenberger G, Fan S, Nicolai L, Busch B, Yavuz G, Luckner
    M, Ishikawa Ankerhold H, Hennel R, Benechet A, Lorenz M, Chandraratne S, Schubert
    I, Helmer S, Striednig B, Stark K, Janko M, Böttcher R, Verschoor A, Leon C, Gachet
    C, Gudermann T, Mederos Y Schnitzler M, Pincus Z, Iannacone M, Haas R, Wanner
    G, Lauber K, Sixt MK, Massberg S. 2017. Migrating platelets are mechano scavengers
    that collect and bundle bacteria. Cell Press. 171(6), 1368–1382.
  mla: Gärtner, Florian R., et al. “Migrating Platelets Are Mechano Scavengers That
    Collect and Bundle Bacteria.” <i>Cell Press</i>, vol. 171, no. 6, Cell Press,
    2017, pp. 1368–82, doi:<a href="https://doi.org/10.1016/j.cell.2017.11.001">10.1016/j.cell.2017.11.001</a>.
  short: F.R. Gärtner, Z. Ahmad, G. Rosenberger, S. Fan, L. Nicolai, B. Busch, G.
    Yavuz, M. Luckner, H. Ishikawa Ankerhold, R. Hennel, A. Benechet, M. Lorenz, S.
    Chandraratne, I. Schubert, S. Helmer, B. Striednig, K. Stark, M. Janko, R. Böttcher,
    A. Verschoor, C. Leon, C. Gachet, T. Gudermann, M. Mederos Y Schnitzler, Z. Pincus,
    M. Iannacone, R. Haas, G. Wanner, K. Lauber, M.K. Sixt, S. Massberg, Cell Press
    171 (2017) 1368–1382.
date_created: 2018-12-11T11:47:15Z
date_published: 2017-11-30T00:00:00Z
date_updated: 2021-01-12T08:03:15Z
day: '30'
department:
- _id: MiSi
doi: 10.1016/j.cell.2017.11.001
ec_funded: 1
intvolume: '       171'
issue: '6'
language:
- iso: eng
month: '11'
oa_version: None
page: 1368 - 1382
project:
- _id: 260AA4E2-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '747687'
  name: Mechanical Adaptation of Lamellipodial Actin Networks in Migrating Cells
publication: Cell Press
publication_identifier:
  issn:
  - '00928674'
publication_status: published
publisher: Cell Press
publist_id: '7243'
quality_controlled: '1'
scopus_import: 1
status: public
title: Migrating platelets are mechano scavengers that collect and bundle bacteria
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 171
year: '2017'
...
---
_id: '572'
abstract:
- lang: eng
  text: In this review, we summarize the different biosynthesis-related pathways that
    contribute to the regulation of endogenous auxin in plants. We demonstrate that
    all known genes involved in auxin biosynthesis also have a role in root formation,
    from the initiation of a root meristem during embryogenesis to the generation
    of a functional root system with a primary root, secondary lateral root branches
    and adventitious roots. Furthermore, the versatile adaptation of root development
    in response to environmental challenges is mediated by both local and distant
    control of auxin biosynthesis. In conclusion, auxin homeostasis mediated by spatial
    and temporal regulation of auxin biosynthesis plays a central role in determining
    root architecture.
article_number: '2587'
article_processing_charge: No
author:
- first_name: Damilola
  full_name: Olatunji, Damilola
  last_name: Olatunji
- first_name: Danny
  full_name: Geelen, Danny
  last_name: Geelen
- first_name: Inge
  full_name: Verstraeten, Inge
  id: 362BF7FE-F248-11E8-B48F-1D18A9856A87
  last_name: Verstraeten
  orcid: 0000-0001-7241-2328
citation:
  ama: Olatunji D, Geelen D, Verstraeten I. Control of endogenous auxin levels in
    plant root development. <i>International Journal of Molecular Sciences</i>. 2017;18(12).
    doi:<a href="https://doi.org/10.3390/ijms18122587">10.3390/ijms18122587</a>
  apa: Olatunji, D., Geelen, D., &#38; Verstraeten, I. (2017). Control of endogenous
    auxin levels in plant root development. <i>International Journal of Molecular
    Sciences</i>. MDPI. <a href="https://doi.org/10.3390/ijms18122587">https://doi.org/10.3390/ijms18122587</a>
  chicago: Olatunji, Damilola, Danny Geelen, and Inge Verstraeten. “Control of Endogenous
    Auxin Levels in Plant Root Development.” <i>International Journal of Molecular
    Sciences</i>. MDPI, 2017. <a href="https://doi.org/10.3390/ijms18122587">https://doi.org/10.3390/ijms18122587</a>.
  ieee: D. Olatunji, D. Geelen, and I. Verstraeten, “Control of endogenous auxin levels
    in plant root development,” <i>International Journal of Molecular Sciences</i>,
    vol. 18, no. 12. MDPI, 2017.
  ista: Olatunji D, Geelen D, Verstraeten I. 2017. Control of endogenous auxin levels
    in plant root development. International Journal of Molecular Sciences. 18(12),
    2587.
  mla: Olatunji, Damilola, et al. “Control of Endogenous Auxin Levels in Plant Root
    Development.” <i>International Journal of Molecular Sciences</i>, vol. 18, no.
    12, 2587, MDPI, 2017, doi:<a href="https://doi.org/10.3390/ijms18122587">10.3390/ijms18122587</a>.
  short: D. Olatunji, D. Geelen, I. Verstraeten, International Journal of Molecular
    Sciences 18 (2017).
date_created: 2018-12-11T11:47:15Z
date_published: 2017-12-01T00:00:00Z
date_updated: 2021-01-12T08:03:16Z
day: '01'
ddc:
- '580'
department:
- _id: JiFr
doi: 10.3390/ijms18122587
file:
- access_level: open_access
  checksum: 82d51f11e493f7eec02976d9a9a9805e
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:08:55Z
  date_updated: 2020-07-14T12:47:10Z
  file_id: '4718'
  file_name: IST-2017-917-v1+1_ijms-18-02587.pdf
  file_size: 920962
  relation: main_file
file_date_updated: 2020-07-14T12:47:10Z
has_accepted_license: '1'
intvolume: '        18'
issue: '12'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
publication: International Journal of Molecular Sciences
publication_status: published
publisher: MDPI
publist_id: '7242'
pubrep_id: '917'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Control of endogenous auxin levels in plant root development
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 18
year: '2017'
...
---
_id: '5803'
abstract:
- lang: eng
  text: Different distance metrics produce Voronoi diagrams with different properties.
    It is a well-known that on the (real) 2D plane or even on any 3D plane, a Voronoi
    diagram (VD) based on the Euclidean distance metric produces convex Voronoi regions.
    In this paper, we first show that this metric produces a persistent VD on the
    2D digital plane, as it comprises digitally convex Voronoi regions and hence correctly
    approximates the corresponding VD on the 2D real plane. Next, we show that on
    a 3D digital plane D, the Euclidean metric spanning over its voxel set does not
    guarantee a digital VD which is persistent with the real-space VD. As a solution,
    we introduce a novel concept of functional-plane-convexity, which is ensured by
    the Euclidean metric spanning over the pedal set of D. Necessary proofs and some
    visual result have been provided to adjudge the merit and usefulness of the proposed
    concept.
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Ranita
  full_name: Biswas, Ranita
  id: 3C2B033E-F248-11E8-B48F-1D18A9856A87
  last_name: Biswas
  orcid: 0000-0002-5372-7890
- first_name: Partha
  full_name: Bhowmick, Partha
  last_name: Bhowmick
citation:
  ama: 'Biswas R, Bhowmick P. Construction of persistent Voronoi diagram on 3D digital
    plane. In: <i>Combinatorial Image Analysis</i>. Vol 10256. Cham: Springer Nature;
    2017:93-104. doi:<a href="https://doi.org/10.1007/978-3-319-59108-7_8">10.1007/978-3-319-59108-7_8</a>'
  apa: 'Biswas, R., &#38; Bhowmick, P. (2017). Construction of persistent Voronoi
    diagram on 3D digital plane. In <i>Combinatorial image analysis</i> (Vol. 10256,
    pp. 93–104). Cham: Springer Nature. <a href="https://doi.org/10.1007/978-3-319-59108-7_8">https://doi.org/10.1007/978-3-319-59108-7_8</a>'
  chicago: 'Biswas, Ranita, and Partha Bhowmick. “Construction of Persistent Voronoi
    Diagram on 3D Digital Plane.” In <i>Combinatorial Image Analysis</i>, 10256:93–104.
    Cham: Springer Nature, 2017. <a href="https://doi.org/10.1007/978-3-319-59108-7_8">https://doi.org/10.1007/978-3-319-59108-7_8</a>.'
  ieee: 'R. Biswas and P. Bhowmick, “Construction of persistent Voronoi diagram on
    3D digital plane,” in <i>Combinatorial image analysis</i>, vol. 10256, Cham: Springer
    Nature, 2017, pp. 93–104.'
  ista: 'Biswas R, Bhowmick P. 2017.Construction of persistent Voronoi diagram on
    3D digital plane. In: Combinatorial image analysis. LNCS, vol. 10256, 93–104.'
  mla: Biswas, Ranita, and Partha Bhowmick. “Construction of Persistent Voronoi Diagram
    on 3D Digital Plane.” <i>Combinatorial Image Analysis</i>, vol. 10256, Springer
    Nature, 2017, pp. 93–104, doi:<a href="https://doi.org/10.1007/978-3-319-59108-7_8">10.1007/978-3-319-59108-7_8</a>.
  short: R. Biswas, P. Bhowmick, in:, Combinatorial Image Analysis, Springer Nature,
    Cham, 2017, pp. 93–104.
conference:
  end_date: 2017-06-21
  location: Plovdiv, Bulgaria
  name: 'IWCIA: International Workshop on Combinatorial Image Analysis'
  start_date: 2017-06-19
date_created: 2019-01-08T20:42:56Z
date_published: 2017-05-17T00:00:00Z
date_updated: 2022-01-28T07:48:24Z
day: '17'
department:
- _id: HeEd
doi: 10.1007/978-3-319-59108-7_8
extern: '1'
intvolume: '     10256'
language:
- iso: eng
month: '05'
oa_version: None
page: 93-104
place: Cham
publication: Combinatorial image analysis
publication_identifier:
  isbn:
  - 978-3-319-59107-0
  - 978-3-319-59108-7
  issn:
  - 0302-9743
  - 1611-3349
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: Construction of persistent Voronoi diagram on 3D digital plane
type: book_chapter
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 10256
year: '2017'
...
---
_id: '6013'
abstract:
- lang: eng
  text: The first hundred attoseconds of the electron dynamics during strong field
    tunneling ionization are investigated. We quantify theoretically how the electron’s
    classical trajectories in the continuum emerge from the tunneling process and
    test the results with those achieved in parallel from attoclock measurements.
    An especially high sensitivity on the tunneling barrier is accomplished here by
    comparing the momentum distributions of two atomic species of slightly deviating
    atomic potentials (argon and krypton) being ionized under absolutely identical
    conditions with near-infrared laser pulses (1300 nm). The agreement between experiment
    and theory provides clear evidence for a nonzero tunneling time delay and a nonvanishing
    longitudinal momentum of the electron at the “tunnel exit.”
article_number: '023201'
arxiv: 1
author:
- first_name: Nicolas
  full_name: Camus, Nicolas
  last_name: Camus
- first_name: Enderalp
  full_name: Yakaboylu, Enderalp
  id: 38CB71F6-F248-11E8-B48F-1D18A9856A87
  last_name: Yakaboylu
  orcid: 0000-0001-5973-0874
- first_name: Lutz
  full_name: Fechner, Lutz
  last_name: Fechner
- first_name: Michael
  full_name: Klaiber, Michael
  last_name: Klaiber
- first_name: Martin
  full_name: Laux, Martin
  last_name: Laux
- first_name: Yonghao
  full_name: Mi, Yonghao
  last_name: Mi
- first_name: Karen Z.
  full_name: Hatsagortsyan, Karen Z.
  last_name: Hatsagortsyan
- first_name: Thomas
  full_name: Pfeifer, Thomas
  last_name: Pfeifer
- first_name: Christoph H.
  full_name: Keitel, Christoph H.
  last_name: Keitel
- first_name: Robert
  full_name: Moshammer, Robert
  last_name: Moshammer
citation:
  ama: Camus N, Yakaboylu E, Fechner L, et al. Experimental evidence for quantum tunneling
    time. <i>Physical Review Letters</i>. 2017;119(2). doi:<a href="https://doi.org/10.1103/PhysRevLett.119.023201">10.1103/PhysRevLett.119.023201</a>
  apa: Camus, N., Yakaboylu, E., Fechner, L., Klaiber, M., Laux, M., Mi, Y., … Moshammer,
    R. (2017). Experimental evidence for quantum tunneling time. <i>Physical Review
    Letters</i>. American Physical Society. <a href="https://doi.org/10.1103/PhysRevLett.119.023201">https://doi.org/10.1103/PhysRevLett.119.023201</a>
  chicago: Camus, Nicolas, Enderalp Yakaboylu, Lutz Fechner, Michael Klaiber, Martin
    Laux, Yonghao Mi, Karen Z. Hatsagortsyan, Thomas Pfeifer, Christoph H. Keitel,
    and Robert Moshammer. “Experimental Evidence for Quantum Tunneling Time.” <i>Physical
    Review Letters</i>. American Physical Society, 2017. <a href="https://doi.org/10.1103/PhysRevLett.119.023201">https://doi.org/10.1103/PhysRevLett.119.023201</a>.
  ieee: N. Camus <i>et al.</i>, “Experimental evidence for quantum tunneling time,”
    <i>Physical Review Letters</i>, vol. 119, no. 2. American Physical Society, 2017.
  ista: Camus N, Yakaboylu E, Fechner L, Klaiber M, Laux M, Mi Y, Hatsagortsyan KZ,
    Pfeifer T, Keitel CH, Moshammer R. 2017. Experimental evidence for quantum tunneling
    time. Physical Review Letters. 119(2), 023201.
  mla: Camus, Nicolas, et al. “Experimental Evidence for Quantum Tunneling Time.”
    <i>Physical Review Letters</i>, vol. 119, no. 2, 023201, American Physical Society,
    2017, doi:<a href="https://doi.org/10.1103/PhysRevLett.119.023201">10.1103/PhysRevLett.119.023201</a>.
  short: N. Camus, E. Yakaboylu, L. Fechner, M. Klaiber, M. Laux, Y. Mi, K.Z. Hatsagortsyan,
    T. Pfeifer, C.H. Keitel, R. Moshammer, Physical Review Letters 119 (2017).
date_created: 2019-02-14T15:24:13Z
date_published: 2017-07-14T00:00:00Z
date_updated: 2023-02-23T11:13:36Z
day: '14'
department:
- _id: MiLe
doi: 10.1103/PhysRevLett.119.023201
external_id:
  arxiv:
  - '1611.03701'
intvolume: '       119'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1611.03701
month: '07'
oa: 1
oa_version: Preprint
publication: Physical Review Letters
publication_identifier:
  eissn:
  - 1079-7114
  issn:
  - 0031-9007
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
related_material:
  record:
  - id: '313'
    relation: earlier_version
    status: public
scopus_import: 1
status: public
title: Experimental evidence for quantum tunneling time
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 119
year: '2017'
...
---
_id: '604'
abstract:
- lang: eng
  text: In several settings of physics and chemistry one has to deal with molecules
    interacting with some kind of an external environment, be it a gas, a solution,
    or a crystal surface. Understanding molecular processes in the presence of such
    a many-particle bath is inherently challenging, and usually requires large-scale
    numerical computations. Here, we present an alternative approach to the problem,
    based on the notion of the angulon quasiparticle. We show that molecules rotating
    inside superfluid helium nanodroplets and Bose–Einstein condensates form angulons,
    and therefore can be described by straightforward solutions of a simple microscopic
    Hamiltonian. Casting the problem in the language of angulons allows us not only
    to greatly simplify it, but also to gain insights into the origins of the observed
    phenomena and to make predictions for future experimental studies.
alternative_title:
- Theoretical and Computational Chemistry Series
author:
- first_name: Mikhail
  full_name: Lemeshko, Mikhail
  id: 37CB05FA-F248-11E8-B48F-1D18A9856A87
  last_name: Lemeshko
  orcid: 0000-0002-6990-7802
- first_name: Richard
  full_name: Schmidt, Richard
  last_name: Schmidt
citation:
  ama: 'Lemeshko M, Schmidt R. Molecular impurities interacting with a many-particle
    environment: From ultracold gases to helium nanodroplets. In: Dulieu O, Osterwalder
    A, eds. <i>Cold Chemistry: Molecular Scattering and Reactivity Near Absolute Zero
    </i>. Vol 11. Theoretical and Computational Chemistry Series. The Royal Society
    of Chemistry; 2017:444-495. doi:<a href="https://doi.org/10.1039/9781782626800-00444">10.1039/9781782626800-00444</a>'
  apa: 'Lemeshko, M., &#38; Schmidt, R. (2017). Molecular impurities interacting with
    a many-particle environment: From ultracold gases to helium nanodroplets. In O.
    Dulieu &#38; A. Osterwalder (Eds.), <i>Cold Chemistry: Molecular Scattering and
    Reactivity Near Absolute Zero </i> (Vol. 11, pp. 444–495). The Royal Society of
    Chemistry. <a href="https://doi.org/10.1039/9781782626800-00444">https://doi.org/10.1039/9781782626800-00444</a>'
  chicago: 'Lemeshko, Mikhail, and Richard Schmidt. “Molecular Impurities Interacting
    with a Many-Particle Environment: From Ultracold Gases to Helium Nanodroplets.”
    In <i>Cold Chemistry: Molecular Scattering and Reactivity Near Absolute Zero </i>,
    edited by Oliver Dulieu and Andreas Osterwalder, 11:444–95. Theoretical and Computational
    Chemistry Series. The Royal Society of Chemistry, 2017. <a href="https://doi.org/10.1039/9781782626800-00444">https://doi.org/10.1039/9781782626800-00444</a>.'
  ieee: 'M. Lemeshko and R. Schmidt, “Molecular impurities interacting with a many-particle
    environment: From ultracold gases to helium nanodroplets,” in <i>Cold Chemistry:
    Molecular Scattering and Reactivity Near Absolute Zero </i>, vol. 11, O. Dulieu
    and A. Osterwalder, Eds. The Royal Society of Chemistry, 2017, pp. 444–495.'
  ista: 'Lemeshko M, Schmidt R. 2017.Molecular impurities interacting with a many-particle
    environment: From ultracold gases to helium nanodroplets. In: Cold Chemistry:
    Molecular Scattering and Reactivity Near Absolute Zero . Theoretical and Computational
    Chemistry Series, vol. 11, 444–495.'
  mla: 'Lemeshko, Mikhail, and Richard Schmidt. “Molecular Impurities Interacting
    with a Many-Particle Environment: From Ultracold Gases to Helium Nanodroplets.”
    <i>Cold Chemistry: Molecular Scattering and Reactivity Near Absolute Zero </i>,
    edited by Oliver Dulieu and Andreas Osterwalder, vol. 11, The Royal Society of
    Chemistry, 2017, pp. 444–95, doi:<a href="https://doi.org/10.1039/9781782626800-00444">10.1039/9781782626800-00444</a>.'
  short: 'M. Lemeshko, R. Schmidt, in:, O. Dulieu, A. Osterwalder (Eds.), Cold Chemistry:
    Molecular Scattering and Reactivity Near Absolute Zero , The Royal Society of
    Chemistry, 2017, pp. 444–495.'
date_created: 2018-12-11T11:47:27Z
date_published: 2017-12-14T00:00:00Z
date_updated: 2021-01-12T08:05:50Z
day: '14'
department:
- _id: MiLe
doi: 10.1039/9781782626800-00444
editor:
- first_name: Oliver
  full_name: Dulieu, Oliver
  last_name: Dulieu
- first_name: Andreas
  full_name: Osterwalder, Andreas
  last_name: Osterwalder
intvolume: '        11'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1703.06753
month: '12'
oa: 1
oa_version: Submitted Version
page: 444 - 495
publication: 'Cold Chemistry: Molecular Scattering and Reactivity Near Absolute Zero '
publication_identifier:
  issn:
  - '20413181'
publication_status: published
publisher: The Royal Society of Chemistry
publist_id: '7201'
quality_controlled: '1'
scopus_import: 1
series_title: Theoretical and Computational Chemistry Series
status: public
title: 'Molecular impurities interacting with a many-particle environment: From ultracold
  gases to helium nanodroplets'
type: book_chapter
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 11
year: '2017'
...
---
_id: '605'
abstract:
- lang: eng
  text: 'Position based cryptography (PBC), proposed in the seminal work of Chandran,
    Goyal, Moriarty, and Ostrovsky (SIAM J. Computing, 2014), aims at constructing
    cryptographic schemes in which the identity of the user is his geographic position.
    Chandran et al. construct PBC schemes for secure positioning and position-based
    key agreement in the bounded-storage model (Maurer, J. Cryptology, 1992). Apart
    from bounded memory, their security proofs need a strong additional restriction
    on the power of the adversary: he cannot compute joint functions of his inputs.
    Removing this assumption is left as an open problem. We show that an answer to
    this question would resolve a long standing open problem in multiparty communication
    complexity: finding a function that is hard to compute with low communication
    complexity in the simultaneous message model, but easy to compute in the fully
    adaptive model. On a more positive side: we also show some implications in the
    other direction, i.e.: we prove that lower bounds on the communication complexity
    of certain multiparty problems imply existence of PBC primitives. Using this result
    we then show two attractive ways to “bypass” our hardness result: the first uses
    the random oracle model, the second weakens the locality requirement in the bounded-storage
    model to online computability. The random oracle construction is arguably one
    of the simplest proposed so far in this area. Our results indicate that constructing
    improved provably secure protocols for PBC requires a better understanding of
    multiparty communication complexity. This is yet another example where negative
    results in one area (in our case: lower bounds in multiparty communication complexity)
    can be used to construct secure cryptographic schemes.'
alternative_title:
- LNCS
author:
- first_name: Joshua
  full_name: Brody, Joshua
  last_name: Brody
- first_name: Stefan
  full_name: Dziembowski, Stefan
  last_name: Dziembowski
- first_name: Sebastian
  full_name: Faust, Sebastian
  last_name: Faust
- first_name: Krzysztof Z
  full_name: Pietrzak, Krzysztof Z
  id: 3E04A7AA-F248-11E8-B48F-1D18A9856A87
  last_name: Pietrzak
  orcid: 0000-0002-9139-1654
citation:
  ama: 'Brody J, Dziembowski S, Faust S, Pietrzak KZ. Position based cryptography
    and multiparty communication complexity. In: Kalai Y, Reyzin L, eds. Vol 10677.
    Springer; 2017:56-81. doi:<a href="https://doi.org/10.1007/978-3-319-70500-2_3">10.1007/978-3-319-70500-2_3</a>'
  apa: 'Brody, J., Dziembowski, S., Faust, S., &#38; Pietrzak, K. Z. (2017). Position
    based cryptography and multiparty communication complexity. In Y. Kalai &#38;
    L. Reyzin (Eds.) (Vol. 10677, pp. 56–81). Presented at the TCC: Theory of Cryptography
    Conference, Baltimore, MD, United States: Springer. <a href="https://doi.org/10.1007/978-3-319-70500-2_3">https://doi.org/10.1007/978-3-319-70500-2_3</a>'
  chicago: Brody, Joshua, Stefan Dziembowski, Sebastian Faust, and Krzysztof Z Pietrzak.
    “Position Based Cryptography and Multiparty Communication Complexity.” edited
    by Yael Kalai and Leonid Reyzin, 10677:56–81. Springer, 2017. <a href="https://doi.org/10.1007/978-3-319-70500-2_3">https://doi.org/10.1007/978-3-319-70500-2_3</a>.
  ieee: 'J. Brody, S. Dziembowski, S. Faust, and K. Z. Pietrzak, “Position based cryptography
    and multiparty communication complexity,” presented at the TCC: Theory of Cryptography
    Conference, Baltimore, MD, United States, 2017, vol. 10677, pp. 56–81.'
  ista: 'Brody J, Dziembowski S, Faust S, Pietrzak KZ. 2017. Position based cryptography
    and multiparty communication complexity. TCC: Theory of Cryptography Conference,
    LNCS, vol. 10677, 56–81.'
  mla: Brody, Joshua, et al. <i>Position Based Cryptography and Multiparty Communication
    Complexity</i>. Edited by Yael Kalai and Leonid Reyzin, vol. 10677, Springer,
    2017, pp. 56–81, doi:<a href="https://doi.org/10.1007/978-3-319-70500-2_3">10.1007/978-3-319-70500-2_3</a>.
  short: J. Brody, S. Dziembowski, S. Faust, K.Z. Pietrzak, in:, Y. Kalai, L. Reyzin
    (Eds.), Springer, 2017, pp. 56–81.
conference:
  end_date: 2017-11-15
  location: Baltimore, MD, United States
  name: 'TCC: Theory of Cryptography Conference'
  start_date: 2017-11-12
date_created: 2018-12-11T11:47:27Z
date_published: 2017-11-05T00:00:00Z
date_updated: 2021-01-12T08:05:53Z
day: '05'
department:
- _id: KrPi
doi: 10.1007/978-3-319-70500-2_3
ec_funded: 1
editor:
- first_name: Yael
  full_name: Kalai, Yael
  last_name: Kalai
- first_name: Leonid
  full_name: Reyzin, Leonid
  last_name: Reyzin
intvolume: '     10677'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://eprint.iacr.org/2016/536
month: '11'
oa: 1
oa_version: Submitted Version
page: 56 - 81
project:
- _id: 258AA5B2-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '682815'
  name: Teaching Old Crypto New Tricks
publication_identifier:
  isbn:
  - 978-331970499-9
publication_status: published
publisher: Springer
publist_id: '7200'
quality_controlled: '1'
scopus_import: 1
status: public
title: Position based cryptography and multiparty communication complexity
type: conference
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 10677
year: '2017'
...
---
_id: '609'
abstract:
- lang: eng
  text: Several cryptographic schemes and applications are based on functions that
    are both reasonably efficient to compute and moderately hard to invert, including
    client puzzles for Denial-of-Service protection, password protection via salted
    hashes, or recent proof-of-work blockchain systems. Despite their wide use, a
    definition of this concept has not yet been distilled and formalized explicitly.
    Instead, either the applications are proven directly based on the assumptions
    underlying the function, or some property of the function is proven, but the security
    of the application is argued only informally. The goal of this work is to provide
    a (universal) definition that decouples the efforts of designing new moderately
    hard functions and of building protocols based on them, serving as an interface
    between the two. On a technical level, beyond the mentioned definitions, we instantiate
    the model for four different notions of hardness. We extend the work of Alwen
    and Serbinenko (STOC 2015) by providing a general tool for proving security for
    the first notion of memory-hard functions that allows for provably secure applications.
    The tool allows us to recover all of the graph-theoretic techniques developed
    for proving security under the older, non-composable, notion of security used
    by Alwen and Serbinenko. As an application of our definition of moderately hard
    functions, we prove the security of two different schemes for proofs of effort
    (PoE). We also formalize and instantiate the concept of a non-interactive proof
    of effort (niPoE), in which the proof is not bound to a particular communication
    context but rather any bit-string chosen by the prover.
alternative_title:
- LNCS
author:
- first_name: Joel F
  full_name: Alwen, Joel F
  id: 2A8DFA8C-F248-11E8-B48F-1D18A9856A87
  last_name: Alwen
- first_name: Björn
  full_name: Tackmann, Björn
  last_name: Tackmann
citation:
  ama: 'Alwen JF, Tackmann B. Moderately hard functions: Definition, instantiations,
    and applications. In: Kalai Y, Reyzin L, eds. Vol 10677. Springer; 2017:493-526.
    doi:<a href="https://doi.org/10.1007/978-3-319-70500-2_17">10.1007/978-3-319-70500-2_17</a>'
  apa: 'Alwen, J. F., &#38; Tackmann, B. (2017). Moderately hard functions: Definition,
    instantiations, and applications. In Y. Kalai &#38; L. Reyzin (Eds.) (Vol. 10677,
    pp. 493–526). Presented at the TCC: Theory of Cryptography, Baltimore, MD, United
    States: Springer. <a href="https://doi.org/10.1007/978-3-319-70500-2_17">https://doi.org/10.1007/978-3-319-70500-2_17</a>'
  chicago: 'Alwen, Joel F, and Björn Tackmann. “Moderately Hard Functions: Definition,
    Instantiations, and Applications.” edited by Yael Kalai and Leonid Reyzin, 10677:493–526.
    Springer, 2017. <a href="https://doi.org/10.1007/978-3-319-70500-2_17">https://doi.org/10.1007/978-3-319-70500-2_17</a>.'
  ieee: 'J. F. Alwen and B. Tackmann, “Moderately hard functions: Definition, instantiations,
    and applications,” presented at the TCC: Theory of Cryptography, Baltimore, MD,
    United States, 2017, vol. 10677, pp. 493–526.'
  ista: 'Alwen JF, Tackmann B. 2017. Moderately hard functions: Definition, instantiations,
    and applications. TCC: Theory of Cryptography, LNCS, vol. 10677, 493–526.'
  mla: 'Alwen, Joel F., and Björn Tackmann. <i>Moderately Hard Functions: Definition,
    Instantiations, and Applications</i>. Edited by Yael Kalai and Leonid Reyzin,
    vol. 10677, Springer, 2017, pp. 493–526, doi:<a href="https://doi.org/10.1007/978-3-319-70500-2_17">10.1007/978-3-319-70500-2_17</a>.'
  short: J.F. Alwen, B. Tackmann, in:, Y. Kalai, L. Reyzin (Eds.), Springer, 2017,
    pp. 493–526.
conference:
  end_date: 2017-11-15
  location: Baltimore, MD, United States
  name: 'TCC: Theory of Cryptography'
  start_date: 2017-11-12
date_created: 2018-12-11T11:47:28Z
date_published: 2017-11-05T00:00:00Z
date_updated: 2021-01-12T08:06:04Z
day: '05'
department:
- _id: KrPi
doi: 10.1007/978-3-319-70500-2_17
editor:
- first_name: Yael
  full_name: Kalai, Yael
  last_name: Kalai
- first_name: Leonid
  full_name: Reyzin, Leonid
  last_name: Reyzin
intvolume: '     10677'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://eprint.iacr.org/2017/945
month: '11'
oa: 1
oa_version: Submitted Version
page: 493 - 526
publication_identifier:
  isbn:
  - 978-331970499-9
publication_status: published
publisher: Springer
publist_id: '7196'
quality_controlled: '1'
scopus_import: 1
status: public
title: 'Moderately hard functions: Definition, instantiations, and applications'
type: conference
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 10677
year: '2017'
...
---
_id: '610'
abstract:
- lang: eng
  text: 'The fact that the complete graph K5 does not embed in the plane has been
    generalized in two independent directions. On the one hand, the solution of the
    classical Heawood problem for graphs on surfaces established that the complete
    graph Kn embeds in a closed surface M (other than the Klein bottle) if and only
    if (n−3)(n−4) ≤ 6b1(M), where b1(M) is the first Z2-Betti number of M. On the
    other hand, van Kampen and Flores proved that the k-skeleton of the n-dimensional
    simplex (the higher-dimensional analogue of Kn+1) embeds in R2k if and only if
    n ≤ 2k + 1. Two decades ago, Kühnel conjectured that the k-skeleton of the n-simplex
    embeds in a compact, (k − 1)-connected 2k-manifold with kth Z2-Betti number bk
    only if the following generalized Heawood inequality holds: (k+1 n−k−1) ≤ (k+1
    2k+1)bk. This is a common generalization of the case of graphs on surfaces as
    well as the van Kampen–Flores theorem. In the spirit of Kühnel’s conjecture, we
    prove that if the k-skeleton of the n-simplex embeds in a compact 2k-manifold
    with kth Z2-Betti number bk, then n ≤ 2bk(k 2k+2)+2k+4. This bound is weaker than
    the generalized Heawood inequality, but does not require the assumption that M
    is (k−1)-connected. Our results generalize to maps without q-covered points, in
    the spirit of Tverberg’s theorem, for q a prime power. Our proof uses a result
    of Volovikov about maps that satisfy a certain homological triviality condition.'
acknowledgement: The work by Z. P. was partially supported by the Israel Science Foundation
  grant ISF-768/12. The work by Z. P. and M. T. was partially supported by the project
  CE-ITI (GACR P202/12/G061) of the Czech Science Foundation and by the ERC Advanced
  Grant No. 267165. Part of the research work of M.T. was conducted at IST Austria,
  supported by an IST Fellowship. The research of P. P. was supported by the ERC Advanced
  grant no. 320924. The work by I. M. and U. W. was supported by the Swiss National
  Science Foundation (grants SNSF-200020-138230 and SNSF-PP00P2-138948). The collaboration
  between U. W. and X. G. was partially supported by the LabEx Bézout (ANR-10-LABX-58).
author:
- first_name: Xavier
  full_name: Goaoc, Xavier
  last_name: Goaoc
- first_name: Isaac
  full_name: Mabillard, Isaac
  id: 32BF9DAA-F248-11E8-B48F-1D18A9856A87
  last_name: Mabillard
- first_name: Pavel
  full_name: Paták, Pavel
  last_name: Paták
- first_name: Zuzana
  full_name: Patakova, Zuzana
  id: 48B57058-F248-11E8-B48F-1D18A9856A87
  last_name: Patakova
  orcid: 0000-0002-3975-1683
- first_name: Martin
  full_name: Tancer, Martin
  id: 38AC689C-F248-11E8-B48F-1D18A9856A87
  last_name: Tancer
  orcid: 0000-0002-1191-6714
- first_name: Uli
  full_name: Wagner, Uli
  id: 36690CA2-F248-11E8-B48F-1D18A9856A87
  last_name: Wagner
  orcid: 0000-0002-1494-0568
citation:
  ama: 'Goaoc X, Mabillard I, Paták P, Patakova Z, Tancer M, Wagner U. On generalized
    Heawood inequalities for manifolds: A van Kampen–Flores type nonembeddability
    result. <i>Israel Journal of Mathematics</i>. 2017;222(2):841-866. doi:<a href="https://doi.org/10.1007/s11856-017-1607-7">10.1007/s11856-017-1607-7</a>'
  apa: 'Goaoc, X., Mabillard, I., Paták, P., Patakova, Z., Tancer, M., &#38; Wagner,
    U. (2017). On generalized Heawood inequalities for manifolds: A van Kampen–Flores
    type nonembeddability result. <i>Israel Journal of Mathematics</i>. Springer.
    <a href="https://doi.org/10.1007/s11856-017-1607-7">https://doi.org/10.1007/s11856-017-1607-7</a>'
  chicago: 'Goaoc, Xavier, Isaac Mabillard, Pavel Paták, Zuzana Patakova, Martin Tancer,
    and Uli Wagner. “On Generalized Heawood Inequalities for Manifolds: A van Kampen–Flores
    Type Nonembeddability Result.” <i>Israel Journal of Mathematics</i>. Springer,
    2017. <a href="https://doi.org/10.1007/s11856-017-1607-7">https://doi.org/10.1007/s11856-017-1607-7</a>.'
  ieee: 'X. Goaoc, I. Mabillard, P. Paták, Z. Patakova, M. Tancer, and U. Wagner,
    “On generalized Heawood inequalities for manifolds: A van Kampen–Flores type nonembeddability
    result,” <i>Israel Journal of Mathematics</i>, vol. 222, no. 2. Springer, pp.
    841–866, 2017.'
  ista: 'Goaoc X, Mabillard I, Paták P, Patakova Z, Tancer M, Wagner U. 2017. On generalized
    Heawood inequalities for manifolds: A van Kampen–Flores type nonembeddability
    result. Israel Journal of Mathematics. 222(2), 841–866.'
  mla: 'Goaoc, Xavier, et al. “On Generalized Heawood Inequalities for Manifolds:
    A van Kampen–Flores Type Nonembeddability Result.” <i>Israel Journal of Mathematics</i>,
    vol. 222, no. 2, Springer, 2017, pp. 841–66, doi:<a href="https://doi.org/10.1007/s11856-017-1607-7">10.1007/s11856-017-1607-7</a>.'
  short: X. Goaoc, I. Mabillard, P. Paták, Z. Patakova, M. Tancer, U. Wagner, Israel
    Journal of Mathematics 222 (2017) 841–866.
date_created: 2018-12-11T11:47:29Z
date_published: 2017-10-01T00:00:00Z
date_updated: 2023-02-23T10:02:13Z
day: '01'
department:
- _id: UlWa
doi: 10.1007/s11856-017-1607-7
ec_funded: 1
intvolume: '       222'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1610.09063
month: '10'
oa: 1
oa_version: Preprint
page: 841 - 866
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '291734'
  name: International IST Postdoc Fellowship Programme
publication: Israel Journal of Mathematics
publication_status: published
publisher: Springer
publist_id: '7194'
quality_controlled: '1'
related_material:
  record:
  - id: '1511'
    relation: earlier_version
    status: public
scopus_import: 1
status: public
title: 'On generalized Heawood inequalities for manifolds: A van Kampen–Flores type
  nonembeddability result'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 222
year: '2017'
...
---
_id: '611'
abstract:
- lang: eng
  text: Small RNAs (sRNAs) regulate genes in plants and animals. Here, we show that
    population-wide differences in color patterns in snapdragon flowers are caused
    by an inverted duplication that generates sRNAs. The complexity and size of the
    transcripts indicate that the duplication represents an intermediate on the pathway
    to microRNA evolution. The sRNAs repress a pigment biosynthesis gene, creating
    a yellow highlight at the site of pollinator entry. The inverted duplication exhibits
    steep clines in allele frequency in a natural hybrid zone, showing that the allele
    is under selection. Thus, regulatory interactions of evolutionarily recent sRNAs
    can be acted upon by selection and contribute to the evolution of phenotypic diversity.
author:
- first_name: Desmond
  full_name: Bradley, Desmond
  last_name: Bradley
- first_name: Ping
  full_name: Xu, Ping
  last_name: Xu
- first_name: Irina
  full_name: Mohorianu, Irina
  last_name: Mohorianu
- first_name: Annabel
  full_name: Whibley, Annabel
  last_name: Whibley
- first_name: David
  full_name: Field, David
  id: 419049E2-F248-11E8-B48F-1D18A9856A87
  last_name: Field
  orcid: 0000-0002-4014-8478
- first_name: Hugo
  full_name: Tavares, Hugo
  last_name: Tavares
- first_name: Matthew
  full_name: Couchman, Matthew
  last_name: Couchman
- first_name: Lucy
  full_name: Copsey, Lucy
  last_name: Copsey
- first_name: Rosemary
  full_name: Carpenter, Rosemary
  last_name: Carpenter
- first_name: Miaomiao
  full_name: Li, Miaomiao
  last_name: Li
- first_name: Qun
  full_name: Li, Qun
  last_name: Li
- first_name: Yongbiao
  full_name: Xue, Yongbiao
  last_name: Xue
- first_name: Tamas
  full_name: Dalmay, Tamas
  last_name: Dalmay
- first_name: Enrico
  full_name: Coen, Enrico
  last_name: Coen
citation:
  ama: Bradley D, Xu P, Mohorianu I, et al. Evolution of flower color pattern through
    selection on regulatory small RNAs. <i>Science</i>. 2017;358(6365):925-928. doi:<a
    href="https://doi.org/10.1126/science.aao3526">10.1126/science.aao3526</a>
  apa: Bradley, D., Xu, P., Mohorianu, I., Whibley, A., Field, D., Tavares, H., …
    Coen, E. (2017). Evolution of flower color pattern through selection on regulatory
    small RNAs. <i>Science</i>. American Association for the Advancement of Science.
    <a href="https://doi.org/10.1126/science.aao3526">https://doi.org/10.1126/science.aao3526</a>
  chicago: Bradley, Desmond, Ping Xu, Irina Mohorianu, Annabel Whibley, David Field,
    Hugo Tavares, Matthew Couchman, et al. “Evolution of Flower Color Pattern through
    Selection on Regulatory Small RNAs.” <i>Science</i>. American Association for
    the Advancement of Science, 2017. <a href="https://doi.org/10.1126/science.aao3526">https://doi.org/10.1126/science.aao3526</a>.
  ieee: D. Bradley <i>et al.</i>, “Evolution of flower color pattern through selection
    on regulatory small RNAs,” <i>Science</i>, vol. 358, no. 6365. American Association
    for the Advancement of Science, pp. 925–928, 2017.
  ista: Bradley D, Xu P, Mohorianu I, Whibley A, Field D, Tavares H, Couchman M, Copsey
    L, Carpenter R, Li M, Li Q, Xue Y, Dalmay T, Coen E. 2017. Evolution of flower
    color pattern through selection on regulatory small RNAs. Science. 358(6365),
    925–928.
  mla: Bradley, Desmond, et al. “Evolution of Flower Color Pattern through Selection
    on Regulatory Small RNAs.” <i>Science</i>, vol. 358, no. 6365, American Association
    for the Advancement of Science, 2017, pp. 925–28, doi:<a href="https://doi.org/10.1126/science.aao3526">10.1126/science.aao3526</a>.
  short: D. Bradley, P. Xu, I. Mohorianu, A. Whibley, D. Field, H. Tavares, M. Couchman,
    L. Copsey, R. Carpenter, M. Li, Q. Li, Y. Xue, T. Dalmay, E. Coen, Science 358
    (2017) 925–928.
date_created: 2018-12-11T11:47:29Z
date_published: 2017-11-17T00:00:00Z
date_updated: 2021-01-12T08:06:10Z
day: '17'
department:
- _id: NiBa
doi: 10.1126/science.aao3526
intvolume: '       358'
issue: '6365'
language:
- iso: eng
month: '11'
oa_version: None
page: 925 - 928
publication: Science
publication_identifier:
  issn:
  - '00368075'
publication_status: published
publisher: American Association for the Advancement of Science
publist_id: '7193'
quality_controlled: '1'
scopus_import: 1
status: public
title: Evolution of flower color pattern through selection on regulatory small RNAs
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 358
year: '2017'
...
---
_id: '613'
abstract:
- lang: eng
  text: 'Bacteria in groups vary individually, and interact with other bacteria and
    the environment to produce population-level patterns of gene expression. Investigating
    such behavior in detail requires measuring and controlling populations at the
    single-cell level alongside precisely specified interactions and environmental
    characteristics. Here we present an automated, programmable platform that combines
    image-based gene expression and growth measurements with on-line optogenetic expression
    control for hundreds of individual Escherichia coli cells over days, in a dynamically
    adjustable environment. This integrated platform broadly enables experiments that
    bridge individual and population behaviors. We demonstrate: (i) population structuring
    by independent closed-loop control of gene expression in many individual cells,
    (ii) cell-cell variation control during antibiotic perturbation, (iii) hybrid
    bio-digital circuits in single cells, and freely specifiable digital communication
    between individual bacteria. These examples showcase the potential for real-time
    integration of theoretical models with measurement and control of many individual
    cells to investigate and engineer microbial population behavior.'
acknowledgement: We are grateful to M. Lang, H. Janovjak, M. Khammash, A. Milias-Argeitis,
  M. Rullan, G. Batt, A. Bosma-Moody, Aryan, S. Leibler, and members of the Guet and
  Tkačik groups for helpful discussion, comments, and suggestions. We thank A. Moglich,
  T. Mathes, J. Tabor, and S. Schmidl for kind gifts of strains, and R. Hauschild,
  B. Knep, M. Lang, T. Asenov, E. Papusheva, T. Menner, T. Adletzberger, and J. Merrin
  for technical assistance. The research leading to these results has received funding
  from the People Programme (Marie Curie Actions) of the European Union’s Seventh
  Framework Programme (FP7/2007–2013) under REA grant agreement no. [291734]. (to
  R.C. and J.R.), Austrian Science Fund grant FWF P28844 (to G.T.), and internal IST
  Austria Interdisciplinary Project Support. J.R. acknowledges support from the Agence
  Nationale de la Recherche (ANR) under Grant Nos. ANR-16-CE33-0018 (MEMIP), ANR-16-CE12-0025
  (COGEX) and ANR-10-BINF-06-01 (ICEBERG).
article_number: '1535'
article_processing_charge: Yes (in subscription journal)
author:
- first_name: Remy P
  full_name: Chait, Remy P
  id: 3464AE84-F248-11E8-B48F-1D18A9856A87
  last_name: Chait
  orcid: 0000-0003-0876-3187
- first_name: Jakob
  full_name: Ruess, Jakob
  id: 4A245D00-F248-11E8-B48F-1D18A9856A87
  last_name: Ruess
  orcid: 0000-0003-1615-3282
- first_name: Tobias
  full_name: Bergmiller, Tobias
  id: 2C471CFA-F248-11E8-B48F-1D18A9856A87
  last_name: Bergmiller
  orcid: 0000-0001-5396-4346
- first_name: Gasper
  full_name: Tkacik, Gasper
  id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
  last_name: Tkacik
  orcid: 0000-0002-6699-1455
- first_name: Calin C
  full_name: Guet, Calin C
  id: 47F8433E-F248-11E8-B48F-1D18A9856A87
  last_name: Guet
  orcid: 0000-0001-6220-2052
citation:
  ama: Chait RP, Ruess J, Bergmiller T, Tkačik G, Guet CC. Shaping bacterial population
    behavior through computer interfaced control of individual cells. <i>Nature Communications</i>.
    2017;8(1). doi:<a href="https://doi.org/10.1038/s41467-017-01683-1">10.1038/s41467-017-01683-1</a>
  apa: Chait, R. P., Ruess, J., Bergmiller, T., Tkačik, G., &#38; Guet, C. C. (2017).
    Shaping bacterial population behavior through computer interfaced control of individual
    cells. <i>Nature Communications</i>. Nature Publishing Group. <a href="https://doi.org/10.1038/s41467-017-01683-1">https://doi.org/10.1038/s41467-017-01683-1</a>
  chicago: Chait, Remy P, Jakob Ruess, Tobias Bergmiller, Gašper Tkačik, and Calin
    C Guet. “Shaping Bacterial Population Behavior through Computer Interfaced Control
    of Individual Cells.” <i>Nature Communications</i>. Nature Publishing Group, 2017.
    <a href="https://doi.org/10.1038/s41467-017-01683-1">https://doi.org/10.1038/s41467-017-01683-1</a>.
  ieee: R. P. Chait, J. Ruess, T. Bergmiller, G. Tkačik, and C. C. Guet, “Shaping
    bacterial population behavior through computer interfaced control of individual
    cells,” <i>Nature Communications</i>, vol. 8, no. 1. Nature Publishing Group,
    2017.
  ista: Chait RP, Ruess J, Bergmiller T, Tkačik G, Guet CC. 2017. Shaping bacterial
    population behavior through computer interfaced control of individual cells. Nature
    Communications. 8(1), 1535.
  mla: Chait, Remy P., et al. “Shaping Bacterial Population Behavior through Computer
    Interfaced Control of Individual Cells.” <i>Nature Communications</i>, vol. 8,
    no. 1, 1535, Nature Publishing Group, 2017, doi:<a href="https://doi.org/10.1038/s41467-017-01683-1">10.1038/s41467-017-01683-1</a>.
  short: R.P. Chait, J. Ruess, T. Bergmiller, G. Tkačik, C.C. Guet, Nature Communications
    8 (2017).
date_created: 2018-12-11T11:47:30Z
date_published: 2017-12-01T00:00:00Z
date_updated: 2021-01-12T08:06:15Z
day: '01'
ddc:
- '576'
- '579'
department:
- _id: CaGu
- _id: GaTk
doi: 10.1038/s41467-017-01683-1
ec_funded: 1
file:
- access_level: open_access
  checksum: 44bb5d0229926c23a9955d9fe0f9723f
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:16:05Z
  date_updated: 2020-07-14T12:47:20Z
  file_id: '5190'
  file_name: IST-2017-911-v1+1_s41467-017-01683-1.pdf
  file_size: 1951699
  relation: main_file
file_date_updated: 2020-07-14T12:47:20Z
has_accepted_license: '1'
intvolume: '         8'
issue: '1'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
project:
- _id: 25681D80-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '291734'
  name: International IST Postdoc Fellowship Programme
- _id: 254E9036-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: P28844-B27
  name: Biophysics of information processing in gene regulation
publication: Nature Communications
publication_identifier:
  issn:
  - '20411723'
publication_status: published
publisher: Nature Publishing Group
publist_id: '7191'
pubrep_id: '911'
quality_controlled: '1'
scopus_import: 1
status: public
title: Shaping bacterial population behavior through computer interfaced control of
  individual cells
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 8
year: '2017'
...
---
_id: '614'
abstract:
- lang: eng
  text: 'Moths and butterflies (Lepidoptera) usually have a pair of differentiated
    WZ sex chromosomes. However, in most lineages outside of the division Ditrysia,
    as well as in the sister order Trichoptera, females lack a W chromosome. The W
    is therefore thought to have been acquired secondarily. Here we compare the genomes
    of three Lepidoptera species (one Dytrisia and two non-Dytrisia) to test three
    models accounting for the origin of the W: (1) a Z-autosome fusion; (2) a sex
    chromosome turnover; and (3) a non-canonical mechanism (e.g., through the recruitment
    of a B chromosome). We show that the gene content of the Z is highly conserved
    across Lepidoptera (rejecting a sex chromosome turnover) and that very few genes
    moved onto the Z in the common ancestor of the Ditrysia (arguing against a Z-autosome
    fusion). Our comparative genomics analysis therefore supports the secondary acquisition
    of the Lepidoptera W by a non-canonical mechanism, and it confirms the extreme
    stability of well-differentiated sex chromosomes.'
article_number: '1486'
article_processing_charge: No
article_type: original
author:
- first_name: Christelle
  full_name: Fraisse, Christelle
  id: 32DF5794-F248-11E8-B48F-1D18A9856A87
  last_name: Fraisse
  orcid: 0000-0001-8441-5075
- first_name: Marion A
  full_name: Picard, Marion A
  id: 2C921A7A-F248-11E8-B48F-1D18A9856A87
  last_name: Picard
  orcid: 0000-0002-8101-2518
- first_name: Beatriz
  full_name: Vicoso, Beatriz
  id: 49E1C5C6-F248-11E8-B48F-1D18A9856A87
  last_name: Vicoso
  orcid: 0000-0002-4579-8306
citation:
  ama: Fraisse C, Picard MAL, Vicoso B. The deep conservation of the Lepidoptera Z
    chromosome suggests a non canonical origin of the W. <i>Nature Communications</i>.
    2017;8(1). doi:<a href="https://doi.org/10.1038/s41467-017-01663-5">10.1038/s41467-017-01663-5</a>
  apa: Fraisse, C., Picard, M. A. L., &#38; Vicoso, B. (2017). The deep conservation
    of the Lepidoptera Z chromosome suggests a non canonical origin of the W. <i>Nature
    Communications</i>. Nature Publishing Group. <a href="https://doi.org/10.1038/s41467-017-01663-5">https://doi.org/10.1038/s41467-017-01663-5</a>
  chicago: Fraisse, Christelle, Marion A L Picard, and Beatriz Vicoso. “The Deep Conservation
    of the Lepidoptera Z Chromosome Suggests a Non Canonical Origin of the W.” <i>Nature
    Communications</i>. Nature Publishing Group, 2017. <a href="https://doi.org/10.1038/s41467-017-01663-5">https://doi.org/10.1038/s41467-017-01663-5</a>.
  ieee: C. Fraisse, M. A. L. Picard, and B. Vicoso, “The deep conservation of the
    Lepidoptera Z chromosome suggests a non canonical origin of the W,” <i>Nature
    Communications</i>, vol. 8, no. 1. Nature Publishing Group, 2017.
  ista: Fraisse C, Picard MAL, Vicoso B. 2017. The deep conservation of the Lepidoptera
    Z chromosome suggests a non canonical origin of the W. Nature Communications.
    8(1), 1486.
  mla: Fraisse, Christelle, et al. “The Deep Conservation of the Lepidoptera Z Chromosome
    Suggests a Non Canonical Origin of the W.” <i>Nature Communications</i>, vol.
    8, no. 1, 1486, Nature Publishing Group, 2017, doi:<a href="https://doi.org/10.1038/s41467-017-01663-5">10.1038/s41467-017-01663-5</a>.
  short: C. Fraisse, M.A.L. Picard, B. Vicoso, Nature Communications 8 (2017).
date_created: 2018-12-11T11:47:30Z
date_published: 2017-12-01T00:00:00Z
date_updated: 2024-02-21T13:47:47Z
day: '01'
ddc:
- '570'
- '576'
department:
- _id: BeVi
- _id: NiBa
doi: 10.1038/s41467-017-01663-5
external_id:
  pmid:
  - '29133797'
file:
- access_level: open_access
  checksum: 4da2651303c8afc2f7fc419be42a2433
  content_type: application/pdf
  creator: dernst
  date_created: 2020-03-03T15:55:50Z
  date_updated: 2020-07-14T12:47:20Z
  file_id: '7562'
  file_name: 2017_NatureComm_Fraisse.pdf
  file_size: 1201520
  relation: main_file
file_date_updated: 2020-07-14T12:47:20Z
has_accepted_license: '1'
intvolume: '         8'
issue: '1'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 250ED89C-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: P28842-B22
  name: Sex chromosome evolution under male- and female- heterogamety
publication: Nature Communications
publication_identifier:
  issn:
  - '20411723'
publication_status: published
publisher: Nature Publishing Group
publist_id: '7190'
pubrep_id: '910'
quality_controlled: '1'
related_material:
  record:
  - id: '7163'
    relation: popular_science
    status: public
scopus_import: 1
status: public
title: The deep conservation of the Lepidoptera Z chromosome suggests a non canonical
  origin of the W
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 8
year: '2017'
...
---
_id: '615'
abstract:
- lang: eng
  text: We show that the Dyson Brownian Motion exhibits local universality after a
    very short time assuming that local rigidity and level repulsion of the eigenvalues
    hold. These conditions are verified, hence bulk spectral universality is proven,
    for a large class of Wigner-like matrices, including deformed Wigner ensembles
    and ensembles with non-stochastic variance matrices whose limiting densities differ
    from Wigner's semicircle law.
author:
- first_name: László
  full_name: Erdös, László
  id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
  last_name: Erdös
  orcid: 0000-0001-5366-9603
- first_name: Kevin
  full_name: Schnelli, Kevin
  id: 434AD0AE-F248-11E8-B48F-1D18A9856A87
  last_name: Schnelli
  orcid: 0000-0003-0954-3231
citation:
  ama: Erdös L, Schnelli K. Universality for random matrix flows with time dependent
    density. <i>Annales de l’institut Henri Poincare (B) Probability and Statistics</i>.
    2017;53(4):1606-1656. doi:<a href="https://doi.org/10.1214/16-AIHP765">10.1214/16-AIHP765</a>
  apa: Erdös, L., &#38; Schnelli, K. (2017). Universality for random matrix flows
    with time dependent density. <i>Annales de l’institut Henri Poincare (B) Probability
    and Statistics</i>. Institute of Mathematical Statistics. <a href="https://doi.org/10.1214/16-AIHP765">https://doi.org/10.1214/16-AIHP765</a>
  chicago: Erdös, László, and Kevin Schnelli. “Universality for Random Matrix Flows
    with Time Dependent Density.” <i>Annales de l’institut Henri Poincare (B) Probability
    and Statistics</i>. Institute of Mathematical Statistics, 2017. <a href="https://doi.org/10.1214/16-AIHP765">https://doi.org/10.1214/16-AIHP765</a>.
  ieee: L. Erdös and K. Schnelli, “Universality for random matrix flows with time
    dependent density,” <i>Annales de l’institut Henri Poincare (B) Probability and
    Statistics</i>, vol. 53, no. 4. Institute of Mathematical Statistics, pp. 1606–1656,
    2017.
  ista: Erdös L, Schnelli K. 2017. Universality for random matrix flows with time
    dependent density. Annales de l’institut Henri Poincare (B) Probability and Statistics.
    53(4), 1606–1656.
  mla: Erdös, László, and Kevin Schnelli. “Universality for Random Matrix Flows with
    Time Dependent Density.” <i>Annales de l’institut Henri Poincare (B) Probability
    and Statistics</i>, vol. 53, no. 4, Institute of Mathematical Statistics, 2017,
    pp. 1606–56, doi:<a href="https://doi.org/10.1214/16-AIHP765">10.1214/16-AIHP765</a>.
  short: L. Erdös, K. Schnelli, Annales de l’institut Henri Poincare (B) Probability
    and Statistics 53 (2017) 1606–1656.
date_created: 2018-12-11T11:47:30Z
date_published: 2017-11-01T00:00:00Z
date_updated: 2021-01-12T08:06:22Z
day: '01'
department:
- _id: LaEr
doi: 10.1214/16-AIHP765
ec_funded: 1
intvolume: '        53'
issue: '4'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1504.00650
month: '11'
oa: 1
oa_version: Submitted Version
page: 1606 - 1656
project:
- _id: 258DCDE6-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '338804'
  name: Random matrices, universality and disordered quantum systems
publication: Annales de l'institut Henri Poincare (B) Probability and Statistics
publication_identifier:
  issn:
  - '02460203'
publication_status: published
publisher: Institute of Mathematical Statistics
publist_id: '7189'
quality_controlled: '1'
scopus_import: 1
status: public
title: Universality for random matrix flows with time dependent density
type: journal_article
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 53
year: '2017'
...
---
_id: '6196'
abstract:
- lang: eng
  text: PMAC is a simple and parallel block-cipher mode of operation, which was introduced
    by Black and Rogaway at Eurocrypt 2002. If instantiated with a (pseudo)random
    permutation over n-bit strings, PMAC constitutes a provably secure variable input-length
    (pseudo)random function. For adversaries making q queries, each of length at most
    l (in n-bit blocks), and of total length σ ≤ ql, the original paper proves an
    upper bound on the distinguishing advantage of  Ο(σ2/2n), while the currently
    best bound is  Ο (qσ/2n).In this work we show that this bound is tight by giving
    an attack with advantage Ω (q2l/2n). In the PMAC construction one initially XORs
    a mask to every message block, where the mask for the ith block is computed as
    τi := γi·L, where L is a (secret) random value, and γi is the i-th codeword of
    the Gray code. Our attack applies more generally to any sequence of γi’s which
    contains a large coset of a subgroup of GF(2n). We then investigate if the security
    of PMAC can be further improved by using τi’s that are k-wise independent, for
    k > 1 (the original distribution is only 1-wise independent). We observe that
    the security of PMAC will not increase in general, even if the masks are chosen
    from a 2-wise independent distribution, and then prove that the security increases
    to O(q<2/2n), if the τi are 4-wise independent. Due to simple extension attacks,
    this is the best bound one can hope for, using any distribution on the masks.
    Whether 3-wise independence is already sufficient to get this level of security
    is left as an open problem.
author:
- first_name: Peter
  full_name: Gazi, Peter
  id: 3E0BFE38-F248-11E8-B48F-1D18A9856A87
  last_name: Gazi
- first_name: Krzysztof Z
  full_name: Pietrzak, Krzysztof Z
  id: 3E04A7AA-F248-11E8-B48F-1D18A9856A87
  last_name: Pietrzak
  orcid: 0000-0002-9139-1654
- first_name: Michal
  full_name: Rybar, Michal
  id: 2B3E3DE8-F248-11E8-B48F-1D18A9856A87
  last_name: Rybar
citation:
  ama: Gazi P, Pietrzak KZ, Rybar M. The exact security of PMAC. <i>IACR Transactions
    on Symmetric Cryptology</i>. 2017;2016(2):145-161. doi:<a href="https://doi.org/10.13154/TOSC.V2016.I2.145-161">10.13154/TOSC.V2016.I2.145-161</a>
  apa: Gazi, P., Pietrzak, K. Z., &#38; Rybar, M. (2017). The exact security of PMAC.
    <i>IACR Transactions on Symmetric Cryptology</i>. Ruhr University Bochum. <a href="https://doi.org/10.13154/TOSC.V2016.I2.145-161">https://doi.org/10.13154/TOSC.V2016.I2.145-161</a>
  chicago: Gazi, Peter, Krzysztof Z Pietrzak, and Michal Rybar. “The Exact Security
    of PMAC.” <i>IACR Transactions on Symmetric Cryptology</i>. Ruhr University Bochum,
    2017. <a href="https://doi.org/10.13154/TOSC.V2016.I2.145-161">https://doi.org/10.13154/TOSC.V2016.I2.145-161</a>.
  ieee: P. Gazi, K. Z. Pietrzak, and M. Rybar, “The exact security of PMAC,” <i>IACR
    Transactions on Symmetric Cryptology</i>, vol. 2016, no. 2. Ruhr University Bochum,
    pp. 145–161, 2017.
  ista: Gazi P, Pietrzak KZ, Rybar M. 2017. The exact security of PMAC. IACR Transactions
    on Symmetric Cryptology. 2016(2), 145–161.
  mla: Gazi, Peter, et al. “The Exact Security of PMAC.” <i>IACR Transactions on Symmetric
    Cryptology</i>, vol. 2016, no. 2, Ruhr University Bochum, 2017, pp. 145–61, doi:<a
    href="https://doi.org/10.13154/TOSC.V2016.I2.145-161">10.13154/TOSC.V2016.I2.145-161</a>.
  short: P. Gazi, K.Z. Pietrzak, M. Rybar, IACR Transactions on Symmetric Cryptology
    2016 (2017) 145–161.
date_created: 2019-04-04T13:48:23Z
date_published: 2017-02-03T00:00:00Z
date_updated: 2023-09-07T12:02:27Z
day: '03'
ddc:
- '000'
department:
- _id: KrPi
doi: 10.13154/TOSC.V2016.I2.145-161
ec_funded: 1
file:
- access_level: open_access
  checksum: f23161d685dd957ae8d7274132999684
  content_type: application/pdf
  creator: dernst
  date_created: 2019-04-04T13:53:58Z
  date_updated: 2020-07-14T12:47:24Z
  file_id: '6197'
  file_name: 2017_IACR_Gazi.pdf
  file_size: 597335
  relation: main_file
file_date_updated: 2020-07-14T12:47:24Z
has_accepted_license: '1'
intvolume: '      2016'
issue: '2'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
page: 145-161
project:
- _id: 258AA5B2-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '682815'
  name: Teaching Old Crypto New Tricks
publication: IACR Transactions on Symmetric Cryptology
publication_identifier:
  eissn:
  - 2519-173X
publication_status: published
publisher: Ruhr University Bochum
quality_controlled: '1'
related_material:
  record:
  - id: '838'
    relation: dissertation_contains
    status: public
status: public
title: The exact security of PMAC
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 2016
year: '2017'
...
---
_id: '621'
abstract:
- lang: eng
  text: The mammalian cerebral cortex is responsible for higher cognitive functions
    such as perception, consciousness, and acquiring and processing information. The
    neocortex is organized into six distinct laminae, each composed of a rich diversity
    of cell types which assemble into highly complex cortical circuits. Radial glia
    progenitors (RGPs) are responsible for producing all neocortical neurons and certain
    glia lineages. Here, we discuss recent discoveries emerging from clonal lineage
    analysis at the single RGP cell level that provide us with an inaugural quantitative
    framework of RGP lineage progression. We further discuss the importance of the
    relative contribution of intrinsic gene functions and non-cell-autonomous or community
    effects in regulating RGP proliferation behavior and lineage progression.
article_processing_charge: Yes (in subscription journal)
author:
- first_name: Robert J
  full_name: Beattie, Robert J
  id: 2E26DF60-F248-11E8-B48F-1D18A9856A87
  last_name: Beattie
  orcid: 0000-0002-8483-8753
- first_name: Simon
  full_name: Hippenmeyer, Simon
  id: 37B36620-F248-11E8-B48F-1D18A9856A87
  last_name: Hippenmeyer
  orcid: 0000-0003-2279-1061
citation:
  ama: Beattie RJ, Hippenmeyer S. Mechanisms of radial glia progenitor cell lineage
    progression. <i>FEBS letters</i>. 2017;591(24):3993-4008. doi:<a href="https://doi.org/10.1002/1873-3468.12906">10.1002/1873-3468.12906</a>
  apa: Beattie, R. J., &#38; Hippenmeyer, S. (2017). Mechanisms of radial glia progenitor
    cell lineage progression. <i>FEBS Letters</i>. Wiley-Blackwell. <a href="https://doi.org/10.1002/1873-3468.12906">https://doi.org/10.1002/1873-3468.12906</a>
  chicago: Beattie, Robert J, and Simon Hippenmeyer. “Mechanisms of Radial Glia Progenitor
    Cell Lineage Progression.” <i>FEBS Letters</i>. Wiley-Blackwell, 2017. <a href="https://doi.org/10.1002/1873-3468.12906">https://doi.org/10.1002/1873-3468.12906</a>.
  ieee: R. J. Beattie and S. Hippenmeyer, “Mechanisms of radial glia progenitor cell
    lineage progression,” <i>FEBS letters</i>, vol. 591, no. 24. Wiley-Blackwell,
    pp. 3993–4008, 2017.
  ista: Beattie RJ, Hippenmeyer S. 2017. Mechanisms of radial glia progenitor cell
    lineage progression. FEBS letters. 591(24), 3993–4008.
  mla: Beattie, Robert J., and Simon Hippenmeyer. “Mechanisms of Radial Glia Progenitor
    Cell Lineage Progression.” <i>FEBS Letters</i>, vol. 591, no. 24, Wiley-Blackwell,
    2017, pp. 3993–4008, doi:<a href="https://doi.org/10.1002/1873-3468.12906">10.1002/1873-3468.12906</a>.
  short: R.J. Beattie, S. Hippenmeyer, FEBS Letters 591 (2017) 3993–4008.
date_created: 2018-12-11T11:47:32Z
date_published: 2017-12-01T00:00:00Z
date_updated: 2024-02-14T12:02:08Z
day: '01'
ddc:
- '571'
- '610'
department:
- _id: SiHi
doi: 10.1002/1873-3468.12906
ec_funded: 1
external_id:
  pmid:
  - '29121403'
file:
- access_level: open_access
  checksum: a46dadc84e0c28d389dd3e9e954464db
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:16:24Z
  date_updated: 2020-07-14T12:47:24Z
  file_id: '5211'
  file_name: IST-2018-928-v1+1_Beattie_et_al-2017-FEBS_Letters.pdf
  file_size: 644149
  relation: main_file
file_date_updated: 2020-07-14T12:47:24Z
has_accepted_license: '1'
intvolume: '       591'
issue: '24'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
page: 3993  - 4008
pmid: 1
project:
- _id: 25D7962E-B435-11E9-9278-68D0E5697425
  grant_number: RGP0053/2014
  name: Quantitative Structure-Function Analysis of Cerebral Cortex Assembly at Clonal
    Level
- _id: 25D61E48-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '618444'
  name: Molecular Mechanisms of Cerebral Cortex Development
publication: FEBS letters
publication_identifier:
  issn:
  - '00145793'
publication_status: published
publisher: Wiley-Blackwell
publist_id: '7183'
pubrep_id: '928'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Mechanisms of radial glia progenitor cell lineage progression
tmp:
  image: /images/cc_by_nc.png
  legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
  short: CC BY-NC (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 591
year: '2017'
...
---
_id: '623'
abstract:
- lang: eng
  text: Genetic factors might be largely responsible for the development of autism
    spectrum disorder (ASD) that alone or in combination with specific environmental
    risk factors trigger the pathology. Multiple mutations identified in ASD patients
    that impair synaptic function in the central nervous system are well studied in
    animal models. How these mutations might interact with other risk factors is not
    fully understood though. Additionally, how systems outside of the brain are altered
    in the context of ASD is an emerging area of research. Extracerebral influences
    on the physiology could begin in utero and contribute to changes in the brain
    and in the development of other body systems and further lead to epigenetic changes.
    Therefore, multiple recent studies have aimed at elucidating the role of gene-environment
    interactions in ASD. Here we provide an overview on the extracerebral systems
    that might play an important associative role in ASD and review evidence regarding
    the potential roles of inflammation, trace metals, metabolism, genetic susceptibility,
    enteric nervous system function and the microbiota of the gastrointestinal (GI)
    tract on the development of endophenotypes in animal models of ASD. By influencing
    environmental conditions, it might be possible to reduce or limit the severity
    of ASD pathology.
alternative_title:
- ADVSANAT
author:
- first_name: Elisa
  full_name: Hill Yardin, Elisa
  last_name: Hill Yardin
- first_name: Sonja
  full_name: Mckeown, Sonja
  last_name: Mckeown
- first_name: Gaia
  full_name: Novarino, Gaia
  id: 3E57A680-F248-11E8-B48F-1D18A9856A87
  last_name: Novarino
  orcid: 0000-0002-7673-7178
- first_name: Andreas
  full_name: Grabrucker, Andreas
  last_name: Grabrucker
citation:
  ama: 'Hill Yardin E, Mckeown S, Novarino G, Grabrucker A. Extracerebral dysfunction
    in animal models of autism spectrum disorder. In: Schmeisser M, Boekers T, eds.
    <i>Translational Anatomy and Cell Biology of Autism Spectrum Disorder</i>. Vol
    224. Advances in Anatomy Embryology and Cell Biology. Springer; 2017:159-187.
    doi:<a href="https://doi.org/10.1007/978-3-319-52498-6_9">10.1007/978-3-319-52498-6_9</a>'
  apa: Hill Yardin, E., Mckeown, S., Novarino, G., &#38; Grabrucker, A. (2017). Extracerebral
    dysfunction in animal models of autism spectrum disorder. In M. Schmeisser &#38;
    T. Boekers (Eds.), <i>Translational Anatomy and Cell Biology of Autism Spectrum
    Disorder</i> (Vol. 224, pp. 159–187). Springer. <a href="https://doi.org/10.1007/978-3-319-52498-6_9">https://doi.org/10.1007/978-3-319-52498-6_9</a>
  chicago: Hill Yardin, Elisa, Sonja Mckeown, Gaia Novarino, and Andreas Grabrucker.
    “Extracerebral Dysfunction in Animal Models of Autism Spectrum Disorder.” In <i>Translational
    Anatomy and Cell Biology of Autism Spectrum Disorder</i>, edited by Michael Schmeisser
    and Tobias Boekers, 224:159–87. Advances in Anatomy Embryology and Cell Biology.
    Springer, 2017. <a href="https://doi.org/10.1007/978-3-319-52498-6_9">https://doi.org/10.1007/978-3-319-52498-6_9</a>.
  ieee: E. Hill Yardin, S. Mckeown, G. Novarino, and A. Grabrucker, “Extracerebral
    dysfunction in animal models of autism spectrum disorder,” in <i>Translational
    Anatomy and Cell Biology of Autism Spectrum Disorder</i>, vol. 224, M. Schmeisser
    and T. Boekers, Eds. Springer, 2017, pp. 159–187.
  ista: 'Hill Yardin E, Mckeown S, Novarino G, Grabrucker A. 2017.Extracerebral dysfunction
    in animal models of autism spectrum disorder. In: Translational Anatomy and Cell
    Biology of Autism Spectrum Disorder. ADVSANAT, vol. 224, 159–187.'
  mla: Hill Yardin, Elisa, et al. “Extracerebral Dysfunction in Animal Models of Autism
    Spectrum Disorder.” <i>Translational Anatomy and Cell Biology of Autism Spectrum
    Disorder</i>, edited by Michael Schmeisser and Tobias Boekers, vol. 224, Springer,
    2017, pp. 159–87, doi:<a href="https://doi.org/10.1007/978-3-319-52498-6_9">10.1007/978-3-319-52498-6_9</a>.
  short: E. Hill Yardin, S. Mckeown, G. Novarino, A. Grabrucker, in:, M. Schmeisser,
    T. Boekers (Eds.), Translational Anatomy and Cell Biology of Autism Spectrum Disorder,
    Springer, 2017, pp. 159–187.
date_created: 2018-12-11T11:47:33Z
date_published: 2017-05-28T00:00:00Z
date_updated: 2021-01-12T08:06:46Z
day: '28'
department:
- _id: GaNo
doi: 10.1007/978-3-319-52498-6_9
editor:
- first_name: Michael
  full_name: Schmeisser, Michael
  last_name: Schmeisser
- first_name: Tobias
  full_name: Boekers, Tobias
  last_name: Boekers
intvolume: '       224'
language:
- iso: eng
month: '05'
oa_version: None
page: 159 - 187
publication: Translational Anatomy and Cell Biology of Autism Spectrum Disorder
publication_identifier:
  isbn:
  - 978-3-319-52496-2
  issn:
  - '03015556'
publication_status: published
publisher: Springer
publist_id: '7177'
quality_controlled: '1'
scopus_import: 1
series_title: Advances in Anatomy Embryology and Cell Biology
status: public
title: Extracerebral dysfunction in animal models of autism spectrum disorder
type: book_chapter
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 224
year: '2017'
...
---
_id: '624'
abstract:
- lang: eng
  text: Bacteria adapt to adverse environmental conditions by altering gene expression
    patterns. Recently, a novel stress adaptation mechanism has been described that
    allows Escherichia coli to alter gene expression at the post-transcriptional level.
    The key player in this regulatory pathway is the endoribonuclease MazF, the toxin
    component of the toxin-antitoxin module mazEF that is triggered by various stressful
    conditions. In general, MazF degrades the majority of transcripts by cleaving
    at ACA sites, which results in the retardation of bacterial growth. Furthermore,
    MazF can process a small subset of mRNAs and render them leaderless by removing
    their ribosome binding site. MazF concomitantly modifies ribosomes, making them
    selective for the translation of leaderless mRNAs. In this study, we employed
    fluorescent reporter-systems to investigate mazEF expression during stressful
    conditions, and to infer consequences of the mRNA processing mediated by MazF
    on gene expression at the single-cell level. Our results suggest that mazEF transcription
    is maintained at low levels in single cells encountering adverse conditions, such
    as antibiotic stress or amino acid starvation. Moreover, using the grcA mRNA as
    a model for MazF-mediated mRNA processing, we found that MazF activation promotes
    heterogeneity in the grcA reporter expression, resulting in a subpopulation of
    cells with increased levels of GrcA reporter protein.
acknowledgement: 'Austrian Science Fund (FWF): M1697, P22249; Swiss National Science
  Foundation (SNF): 145706; European Commission;FWF Special Research Program: RNA-REG
  F43'
article_number: '3830'
author:
- first_name: Nela
  full_name: Nikolic, Nela
  id: 42D9CABC-F248-11E8-B48F-1D18A9856A87
  last_name: Nikolic
  orcid: 0000-0001-9068-6090
- first_name: Zrinka
  full_name: Didara, Zrinka
  last_name: Didara
- first_name: Isabella
  full_name: Moll, Isabella
  last_name: Moll
citation:
  ama: Nikolic N, Didara Z, Moll I. MazF activation promotes translational heterogeneity
    of the grcA mRNA in Escherichia coli populations. <i>PeerJ</i>. 2017;2017(9).
    doi:<a href="https://doi.org/10.7717/peerj.3830">10.7717/peerj.3830</a>
  apa: Nikolic, N., Didara, Z., &#38; Moll, I. (2017). MazF activation promotes translational
    heterogeneity of the grcA mRNA in Escherichia coli populations. <i>PeerJ</i>.
    PeerJ. <a href="https://doi.org/10.7717/peerj.3830">https://doi.org/10.7717/peerj.3830</a>
  chicago: Nikolic, Nela, Zrinka Didara, and Isabella Moll. “MazF Activation Promotes
    Translational Heterogeneity of the GrcA MRNA in Escherichia Coli Populations.”
    <i>PeerJ</i>. PeerJ, 2017. <a href="https://doi.org/10.7717/peerj.3830">https://doi.org/10.7717/peerj.3830</a>.
  ieee: N. Nikolic, Z. Didara, and I. Moll, “MazF activation promotes translational
    heterogeneity of the grcA mRNA in Escherichia coli populations,” <i>PeerJ</i>,
    vol. 2017, no. 9. PeerJ, 2017.
  ista: Nikolic N, Didara Z, Moll I. 2017. MazF activation promotes translational
    heterogeneity of the grcA mRNA in Escherichia coli populations. PeerJ. 2017(9),
    3830.
  mla: Nikolic, Nela, et al. “MazF Activation Promotes Translational Heterogeneity
    of the GrcA MRNA in Escherichia Coli Populations.” <i>PeerJ</i>, vol. 2017, no.
    9, 3830, PeerJ, 2017, doi:<a href="https://doi.org/10.7717/peerj.3830">10.7717/peerj.3830</a>.
  short: N. Nikolic, Z. Didara, I. Moll, PeerJ 2017 (2017).
date_created: 2018-12-11T11:47:33Z
date_published: 2017-09-21T00:00:00Z
date_updated: 2021-01-12T08:06:48Z
day: '21'
ddc:
- '579'
department:
- _id: CaGu
doi: 10.7717/peerj.3830
file:
- access_level: open_access
  checksum: 3d79ae6b6eabc90b0eaaed82ff3493b0
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:11:51Z
  date_updated: 2020-07-14T12:47:24Z
  file_id: '4908'
  file_name: IST-2017-909-v1+1_peerj-3830.pdf
  file_size: 682064
  relation: main_file
file_date_updated: 2020-07-14T12:47:24Z
has_accepted_license: '1'
intvolume: '      2017'
issue: '9'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
publication: PeerJ
publication_identifier:
  issn:
  - '21678359'
publication_status: published
publisher: PeerJ
publist_id: '7172'
pubrep_id: '909'
quality_controlled: '1'
scopus_import: 1
status: public
title: MazF activation promotes translational heterogeneity of the grcA mRNA in Escherichia
  coli populations
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 2017
year: '2017'
...
---
_id: '625'
abstract:
- lang: eng
  text: In the analysis of reactive systems a quantitative objective assigns a real
    value to every trace of the system. The value decision problem for a quantitative
    objective requires a trace whose value is at least a given threshold, and the
    exact value decision problem requires a trace whose value is exactly the threshold.
    We compare the computational complexity of the value and exact value decision
    problems for classical quantitative objectives, such as sum, discounted sum, energy,
    and mean-payoff for two standard models of reactive systems, namely, graphs and
    graph games.
acknowledgement: 'This research was supported in part by the Austrian Science Fund
  (FWF) under grants S11402-N23 and S11407-N23 (RiSE/SHiNE), and Z211-N23 (Wittgenstein
  Award), ERC Start grant (279307: Graph Games), Vienna Science and Technology Fund
  (WWTF) through project ICT15-003.'
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Laurent
  full_name: Doyen, Laurent
  last_name: Doyen
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000−0002−2985−7724
citation:
  ama: 'Chatterjee K, Doyen L, Henzinger TA. The cost of exactness in quantitative
    reachability. In: Aceto L, Bacci G, Ingólfsdóttir A, Legay A, Mardare R, eds.
    <i>Models, Algorithms, Logics and Tools</i>. Vol 10460. Theoretical Computer Science
    and General Issues. Springer; 2017:367-381. doi:<a href="https://doi.org/10.1007/978-3-319-63121-9_18">10.1007/978-3-319-63121-9_18</a>'
  apa: Chatterjee, K., Doyen, L., &#38; Henzinger, T. A. (2017). The cost of exactness
    in quantitative reachability. In L. Aceto, G. Bacci, A. Ingólfsdóttir, A. Legay,
    &#38; R. Mardare (Eds.), <i>Models, Algorithms, Logics and Tools</i> (Vol. 10460,
    pp. 367–381). Springer. <a href="https://doi.org/10.1007/978-3-319-63121-9_18">https://doi.org/10.1007/978-3-319-63121-9_18</a>
  chicago: Chatterjee, Krishnendu, Laurent Doyen, and Thomas A Henzinger. “The Cost
    of Exactness in Quantitative Reachability.” In <i>Models, Algorithms, Logics and
    Tools</i>, edited by Luca Aceto, Giorgio Bacci, Anna Ingólfsdóttir, Axel Legay,
    and Radu Mardare, 10460:367–81. Theoretical Computer Science and General Issues.
    Springer, 2017. <a href="https://doi.org/10.1007/978-3-319-63121-9_18">https://doi.org/10.1007/978-3-319-63121-9_18</a>.
  ieee: K. Chatterjee, L. Doyen, and T. A. Henzinger, “The cost of exactness in quantitative
    reachability,” in <i>Models, Algorithms, Logics and Tools</i>, vol. 10460, L.
    Aceto, G. Bacci, A. Ingólfsdóttir, A. Legay, and R. Mardare, Eds. Springer, 2017,
    pp. 367–381.
  ista: 'Chatterjee K, Doyen L, Henzinger TA. 2017.The cost of exactness in quantitative
    reachability. In: Models, Algorithms, Logics and Tools. LNCS, vol. 10460, 367–381.'
  mla: Chatterjee, Krishnendu, et al. “The Cost of Exactness in Quantitative Reachability.”
    <i>Models, Algorithms, Logics and Tools</i>, edited by Luca Aceto et al., vol.
    10460, Springer, 2017, pp. 367–81, doi:<a href="https://doi.org/10.1007/978-3-319-63121-9_18">10.1007/978-3-319-63121-9_18</a>.
  short: K. Chatterjee, L. Doyen, T.A. Henzinger, in:, L. Aceto, G. Bacci, A. Ingólfsdóttir,
    A. Legay, R. Mardare (Eds.), Models, Algorithms, Logics and Tools, Springer, 2017,
    pp. 367–381.
date_created: 2018-12-11T11:47:34Z
date_published: 2017-07-25T00:00:00Z
date_updated: 2025-06-02T08:53:45Z
day: '25'
ddc:
- '000'
department:
- _id: KrCh
- _id: ToHe
doi: 10.1007/978-3-319-63121-9_18
ec_funded: 1
editor:
- first_name: Luca
  full_name: Aceto, Luca
  last_name: Aceto
- first_name: Giorgio
  full_name: Bacci, Giorgio
  last_name: Bacci
- first_name: Anna
  full_name: Ingólfsdóttir, Anna
  last_name: Ingólfsdóttir
- first_name: Axel
  full_name: Legay, Axel
  last_name: Legay
- first_name: Radu
  full_name: Mardare, Radu
  last_name: Mardare
file:
- access_level: open_access
  checksum: b2402766ec02c79801aac634bd8f9f6c
  content_type: application/pdf
  creator: dernst
  date_created: 2019-11-19T08:06:50Z
  date_updated: 2020-07-14T12:47:25Z
  file_id: '7048'
  file_name: 2017_ModelsAlgorithms_Chatterjee.pdf
  file_size: 192826
  relation: main_file
file_date_updated: 2020-07-14T12:47:25Z
has_accepted_license: '1'
intvolume: '     10460'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Submitted Version
page: 367 - 381
project:
- _id: 25F5A88A-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: S11402-N23
  name: Moderne Concurrency Paradigms
- _id: 25863FF4-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: S11407
  name: Game Theory
- _id: 25F42A32-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: Z211
  name: The Wittgenstein Prize
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '279307'
  name: 'Quantitative Graph Games: Theory and Applications'
- _id: 25892FC0-B435-11E9-9278-68D0E5697425
  grant_number: ICT15-003
  name: Efficient Algorithms for Computer Aided Verification
publication: Models, Algorithms, Logics and Tools
publication_identifier:
  isbn:
  - 978-3-319-63120-2
  issn:
  - 0302-9743
publication_status: published
publisher: Springer
publist_id: '7170'
quality_controlled: '1'
scopus_import: '1'
series_title: Theoretical Computer Science and General Issues
status: public
title: The cost of exactness in quantitative reachability
type: book_chapter
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 10460
year: '2017'
...
---
_id: '626'
abstract:
- lang: eng
  text: 'Our focus here is on the infinitesimal model. In this model, one or several
    quantitative traits are described as the sum of a genetic and a non-genetic component,
    the first being distributed within families as a normal random variable centred
    at the average of the parental genetic components, and with a variance independent
    of the parental traits. Thus, the variance that segregates within families is
    not perturbed by selection, and can be predicted from the variance components.
    This does not necessarily imply that the trait distribution across the whole population
    should be Gaussian, and indeed selection or population structure may have a substantial
    effect on the overall trait distribution. One of our main aims is to identify
    some general conditions on the allelic effects for the infinitesimal model to
    be accurate. We first review the long history of the infinitesimal model in quantitative
    genetics. Then we formulate the model at the phenotypic level in terms of individual
    trait values and relationships between individuals, but including different evolutionary
    processes: genetic drift, recombination, selection, mutation, population structure,
    …. We give a range of examples of its application to evolutionary questions related
    to stabilising selection, assortative mating, effective population size and response
    to selection, habitat preference and speciation. We provide a mathematical justification
    of the model as the limit as the number M of underlying loci tends to infinity
    of a model with Mendelian inheritance, mutation and environmental noise, when
    the genetic component of the trait is purely additive. We also show how the model
    generalises to include epistatic effects. We prove in particular that, within
    each family, the genetic components of the individual trait values in the current
    generation are indeed normally distributed with a variance independent of ancestral
    traits, up to an error of order 1∕M. Simulations suggest that in some cases the
    convergence may be as fast as 1∕M.'
author:
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
- first_name: Alison
  full_name: Etheridge, Alison
  last_name: Etheridge
- first_name: Amandine
  full_name: Véber, Amandine
  last_name: Véber
citation:
  ama: 'Barton NH, Etheridge A, Véber A. The infinitesimal model: Definition derivation
    and implications. <i>Theoretical Population Biology</i>. 2017;118:50-73. doi:<a
    href="https://doi.org/10.1016/j.tpb.2017.06.001">10.1016/j.tpb.2017.06.001</a>'
  apa: 'Barton, N. H., Etheridge, A., &#38; Véber, A. (2017). The infinitesimal model:
    Definition derivation and implications. <i>Theoretical Population Biology</i>.
    Academic Press. <a href="https://doi.org/10.1016/j.tpb.2017.06.001">https://doi.org/10.1016/j.tpb.2017.06.001</a>'
  chicago: 'Barton, Nicholas H, Alison Etheridge, and Amandine Véber. “The Infinitesimal
    Model: Definition Derivation and Implications.” <i>Theoretical Population Biology</i>.
    Academic Press, 2017. <a href="https://doi.org/10.1016/j.tpb.2017.06.001">https://doi.org/10.1016/j.tpb.2017.06.001</a>.'
  ieee: 'N. H. Barton, A. Etheridge, and A. Véber, “The infinitesimal model: Definition
    derivation and implications,” <i>Theoretical Population Biology</i>, vol. 118.
    Academic Press, pp. 50–73, 2017.'
  ista: 'Barton NH, Etheridge A, Véber A. 2017. The infinitesimal model: Definition
    derivation and implications. Theoretical Population Biology. 118, 50–73.'
  mla: 'Barton, Nicholas H., et al. “The Infinitesimal Model: Definition Derivation
    and Implications.” <i>Theoretical Population Biology</i>, vol. 118, Academic Press,
    2017, pp. 50–73, doi:<a href="https://doi.org/10.1016/j.tpb.2017.06.001">10.1016/j.tpb.2017.06.001</a>.'
  short: N.H. Barton, A. Etheridge, A. Véber, Theoretical Population Biology 118 (2017)
    50–73.
date_created: 2018-12-11T11:47:34Z
date_published: 2017-12-01T00:00:00Z
date_updated: 2021-01-12T08:06:50Z
day: '01'
ddc:
- '576'
department:
- _id: NiBa
doi: 10.1016/j.tpb.2017.06.001
ec_funded: 1
file:
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file_date_updated: 2020-07-14T12:47:25Z
has_accepted_license: '1'
intvolume: '       118'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
page: 50 - 73
project:
- _id: 25B07788-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '250152'
  name: Limits to selection in biology and in evolutionary computation
publication: Theoretical Population Biology
publication_identifier:
  issn:
  - '00405809'
publication_status: published
publisher: Academic Press
publist_id: '7169'
pubrep_id: '908'
quality_controlled: '1'
scopus_import: 1
status: public
title: 'The infinitesimal model: Definition derivation and implications'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 118
year: '2017'
...
---
_id: '627'
abstract:
- lang: eng
  text: Beige adipocytes are a new type of recruitable brownish adipocytes, with highly
    mitochondrial membrane uncoupling protein 1 expression and thermogenesis. Beige
    adipocytes were found among white adipocytes, especially in subcutaneous white
    adipose tissue (sWAT). Therefore, beige adipocytes may be involved in the regulation
    of energy metabolism and fat deposition. Transient receptor potential melastatin
    8 (TRPM8), a Ca2+-permeable non-selective cation channel, plays vital roles in
    the regulation of various cellular functions. It has been reported that TRPM8
    activation enhanced the thermogenic function of brown adiposytes. However, the
    involvement of TRPM8 in the thermogenic function of WAT remains unexplored. Our
    data revealed that TRPM8 was expressed in mouse white adipocytes at mRNA, protein
    and functional levels. The mRNA expression of Trpm8 was significantly increased
    in the differentiated white adipocytes than pre-adipocytes. Moreover, activation
    of TRPM8 by menthol enhanced the expression of thermogenic genes in cultured white
    aidpocytes. And menthol-induced increases of the thermogenic genes in white adipocytes
    was inhibited by either KT5720 (a protein kinase A inhibitor) or BAPTA-AM. In
    addition, high fat diet (HFD)-induced obesity in mice was significantly recovered
    by co-treatment with menthol. Dietary menthol enhanced WAT &quot;browning&quot;
    and improved glucose metabolism in HFD-induced obesity mice as well. Therefore,
    we concluded that TRPM8 might be involved in WAT &quot;browning&quot; by increasing
    the expression levels of genes related to thermogenesis and energy metabolism.
    And dietary menthol could be a novel approach for combating human obesity and
    related metabolic diseases.
article_processing_charge: No
author:
- first_name: Changyu
  full_name: Jiang, Changyu
  last_name: Jiang
- first_name: Ming-Zhu
  full_name: Zhai, Ming-Zhu
  id: 34009CFA-F248-11E8-B48F-1D18A9856A87
  last_name: Zhai
- first_name: Dong
  full_name: Yan, Dong
  last_name: Yan
- first_name: Da
  full_name: Li, Da
  last_name: Li
- first_name: Chen
  full_name: Li, Chen
  last_name: Li
- first_name: Yonghong
  full_name: Zhang, Yonghong
  last_name: Zhang
- first_name: Lizu
  full_name: Xiao, Lizu
  last_name: Xiao
- first_name: Donglin
  full_name: Xiong, Donglin
  last_name: Xiong
- first_name: Qiwen
  full_name: Deng, Qiwen
  last_name: Deng
- first_name: Wuping
  full_name: Sun, Wuping
  last_name: Sun
citation:
  ama: Jiang C, Zhai M-Z, Yan D, et al. Dietary menthol-induced TRPM8 activation enhances
    WAT “browning” and ameliorates diet-induced obesity. <i>Oncotarget</i>. 2017;8(43):75114-75126.
    doi:<a href="https://doi.org/10.18632/oncotarget.20540">10.18632/oncotarget.20540</a>
  apa: Jiang, C., Zhai, M.-Z., Yan, D., Li, D., Li, C., Zhang, Y., … Sun, W. (2017).
    Dietary menthol-induced TRPM8 activation enhances WAT “browning” and ameliorates
    diet-induced obesity. <i>Oncotarget</i>. Impact Journals. <a href="https://doi.org/10.18632/oncotarget.20540">https://doi.org/10.18632/oncotarget.20540</a>
  chicago: Jiang, Changyu, Ming-Zhu Zhai, Dong Yan, Da Li, Chen Li, Yonghong Zhang,
    Lizu Xiao, Donglin Xiong, Qiwen Deng, and Wuping Sun. “Dietary Menthol-Induced
    TRPM8 Activation Enhances WAT ‘Browning’ and Ameliorates Diet-Induced Obesity.”
    <i>Oncotarget</i>. Impact Journals, 2017. <a href="https://doi.org/10.18632/oncotarget.20540">https://doi.org/10.18632/oncotarget.20540</a>.
  ieee: C. Jiang <i>et al.</i>, “Dietary menthol-induced TRPM8 activation enhances
    WAT ‘browning’ and ameliorates diet-induced obesity,” <i>Oncotarget</i>, vol.
    8, no. 43. Impact Journals, pp. 75114–75126, 2017.
  ista: Jiang C, Zhai M-Z, Yan D, Li D, Li C, Zhang Y, Xiao L, Xiong D, Deng Q, Sun
    W. 2017. Dietary menthol-induced TRPM8 activation enhances WAT “browning” and
    ameliorates diet-induced obesity. Oncotarget. 8(43), 75114–75126.
  mla: Jiang, Changyu, et al. “Dietary Menthol-Induced TRPM8 Activation Enhances WAT
    ‘Browning’ and Ameliorates Diet-Induced Obesity.” <i>Oncotarget</i>, vol. 8, no.
    43, Impact Journals, 2017, pp. 75114–26, doi:<a href="https://doi.org/10.18632/oncotarget.20540">10.18632/oncotarget.20540</a>.
  short: C. Jiang, M.-Z. Zhai, D. Yan, D. Li, C. Li, Y. Zhang, L. Xiao, D. Xiong,
    Q. Deng, W. Sun, Oncotarget 8 (2017) 75114–75126.
date_created: 2018-12-11T11:47:34Z
date_published: 2017-08-24T00:00:00Z
date_updated: 2023-10-17T08:56:37Z
day: '24'
ddc:
- '571'
department:
- _id: RySh
doi: 10.18632/oncotarget.20540
file:
- access_level: open_access
  checksum: 2219e5348bbfe1aac2725aa620c33280
  content_type: application/pdf
  creator: system
  date_created: 2018-12-12T10:16:15Z
  date_updated: 2020-07-14T12:47:26Z
  file_id: '5201'
  file_name: IST-2017-907-v1+1_20540-294640-4-PB.pdf
  file_size: 6101606
  relation: main_file
file_date_updated: 2020-07-14T12:47:26Z
has_accepted_license: '1'
intvolume: '         8'
issue: '43'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
page: 75114 - 75126
publication: Oncotarget
publication_identifier:
  issn:
  - 1949-2553
publication_status: published
publisher: Impact Journals
publist_id: '7167'
pubrep_id: '907'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Dietary menthol-induced TRPM8 activation enhances WAT “browning” and ameliorates
  diet-induced obesity
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 8
year: '2017'
...
---
_id: '628'
abstract:
- lang: eng
  text: We consider the problem of developing automated techniques for solving recurrence
    relations to aid the expected-runtime analysis of programs. The motivation is
    that several classical textbook algorithms have quite efficient expected-runtime
    complexity, whereas the corresponding worst-case bounds are either inefficient
    (e.g., Quick-Sort), or completely ineffective (e.g., Coupon-Collector). Since
    the main focus of expected-runtime analysis is to obtain efficient bounds, we
    consider bounds that are either logarithmic, linear or almost-linear (O(log n),
    O(n), O(n · log n), respectively, where n represents the input size). Our main
    contribution is an efficient (simple linear-time algorithm) sound approach for
    deriving such expected-runtime bounds for the analysis of recurrence relations
    induced by randomized algorithms. The experimental results show that our approach
    can efficiently derive asymptotically optimal expected-runtime bounds for recurrences
    of classical randomized algorithms, including Randomized-Search, Quick-Sort, Quick-Select,
    Coupon-Collector, where the worst-case bounds are either inefficient (such as
    linear as compared to logarithmic expected-runtime complexity, or quadratic as
    compared to linear or almost-linear expected-runtime complexity), or ineffective.
alternative_title:
- LNCS
author:
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Hongfei
  full_name: Fu, Hongfei
  last_name: Fu
- first_name: Aniket
  full_name: Murhekar, Aniket
  last_name: Murhekar
citation:
  ama: 'Chatterjee K, Fu H, Murhekar A. Automated recurrence analysis for almost linear
    expected runtime bounds. In: Majumdar R, Kunčak V, eds. Vol 10426. Springer; 2017:118-139.
    doi:<a href="https://doi.org/10.1007/978-3-319-63387-9_6">10.1007/978-3-319-63387-9_6</a>'
  apa: 'Chatterjee, K., Fu, H., &#38; Murhekar, A. (2017). Automated recurrence analysis
    for almost linear expected runtime bounds. In R. Majumdar &#38; V. Kunčak (Eds.)
    (Vol. 10426, pp. 118–139). Presented at the CAV: Computer Aided Verification,
    Heidelberg, Germany: Springer. <a href="https://doi.org/10.1007/978-3-319-63387-9_6">https://doi.org/10.1007/978-3-319-63387-9_6</a>'
  chicago: Chatterjee, Krishnendu, Hongfei Fu, and Aniket Murhekar. “Automated Recurrence
    Analysis for Almost Linear Expected Runtime Bounds.” edited by Rupak Majumdar
    and Viktor Kunčak, 10426:118–39. Springer, 2017. <a href="https://doi.org/10.1007/978-3-319-63387-9_6">https://doi.org/10.1007/978-3-319-63387-9_6</a>.
  ieee: 'K. Chatterjee, H. Fu, and A. Murhekar, “Automated recurrence analysis for
    almost linear expected runtime bounds,” presented at the CAV: Computer Aided Verification,
    Heidelberg, Germany, 2017, vol. 10426, pp. 118–139.'
  ista: 'Chatterjee K, Fu H, Murhekar A. 2017. Automated recurrence analysis for almost
    linear expected runtime bounds. CAV: Computer Aided Verification, LNCS, vol. 10426,
    118–139.'
  mla: Chatterjee, Krishnendu, et al. <i>Automated Recurrence Analysis for Almost
    Linear Expected Runtime Bounds</i>. Edited by Rupak Majumdar and Viktor Kunčak,
    vol. 10426, Springer, 2017, pp. 118–39, doi:<a href="https://doi.org/10.1007/978-3-319-63387-9_6">10.1007/978-3-319-63387-9_6</a>.
  short: K. Chatterjee, H. Fu, A. Murhekar, in:, R. Majumdar, V. Kunčak (Eds.), Springer,
    2017, pp. 118–139.
conference:
  end_date: 2017-07-28
  location: Heidelberg, Germany
  name: 'CAV: Computer Aided Verification'
  start_date: 2017-07-24
date_created: 2018-12-11T11:47:35Z
date_published: 2017-01-01T00:00:00Z
date_updated: 2021-01-12T08:06:55Z
day: '01'
department:
- _id: KrCh
doi: 10.1007/978-3-319-63387-9_6
ec_funded: 1
editor:
- first_name: Rupak
  full_name: Majumdar, Rupak
  last_name: Majumdar
- first_name: Viktor
  full_name: Kunčak, Viktor
  last_name: Kunčak
intvolume: '     10426'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1705.00314
month: '01'
oa: 1
oa_version: Submitted Version
page: 118 - 139
project:
- _id: 25892FC0-B435-11E9-9278-68D0E5697425
  grant_number: ICT15-003
  name: Efficient Algorithms for Computer Aided Verification
- _id: 25863FF4-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: S11407
  name: Game Theory
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '279307'
  name: 'Quantitative Graph Games: Theory and Applications'
publication_identifier:
  isbn:
  - 978-331963386-2
publication_status: published
publisher: Springer
publist_id: '7166'
quality_controlled: '1'
scopus_import: 1
status: public
title: Automated recurrence analysis for almost linear expected runtime bounds
type: conference
user_id: 4435EBFC-F248-11E8-B48F-1D18A9856A87
volume: 10426
year: '2017'
...
