---
_id: '7650'
abstract:
- lang: eng
  text: We consider a dilute, homogeneous Bose gas at positive temperature. The system
    is investigated in the Gross–Pitaevskii limit, where the scattering length a is
    so small that the interaction energy is of the same order of magnitude as the
    spectral gap of the Laplacian, and for temperatures that are comparable to the
    critical temperature of the ideal gas. We show that the difference between the
    specific free energy of the interacting system and the one of the ideal gas is
    to leading order given by 4πa(2ϱ2−ϱ20). Here ϱ denotes the density of the system
    and ϱ0 is the expected condensate density of the ideal gas. Additionally, we show
    that the one-particle density matrix of any approximate minimizer of the Gibbs
    free energy functional is to leading order given by the one of the ideal gas.
    This in particular proves Bose–Einstein condensation with critical temperature
    given by the one of the ideal gas to leading order. One key ingredient of our
    proof is a novel use of the Gibbs variational principle that goes hand in hand
    with the c-number substitution.
acknowledgement: Open access funding provided by Institute of Science and Technology
  (IST Austria). It is a pleasure to thank Jakob Yngvason for helpful discussions.
  Financial support by the European Research Council (ERC) under the European Union’sHorizon
  2020 research and innovation programme (Grant Agreement No. 694227) is gratefully
  acknowledged. A. D. acknowledges funding from the European Union’s Horizon 2020
  research and innovation programme under the Marie Sklodowska-Curie Grant Agreement
  No. 836146.
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Andreas
  full_name: Deuchert, Andreas
  id: 4DA65CD0-F248-11E8-B48F-1D18A9856A87
  last_name: Deuchert
  orcid: 0000-0003-3146-6746
- first_name: Robert
  full_name: Seiringer, Robert
  id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
  last_name: Seiringer
  orcid: 0000-0002-6781-0521
citation:
  ama: Deuchert A, Seiringer R. Gross-Pitaevskii limit of a homogeneous Bose gas at
    positive temperature. <i>Archive for Rational Mechanics and Analysis</i>. 2020;236(6):1217-1271.
    doi:<a href="https://doi.org/10.1007/s00205-020-01489-4">10.1007/s00205-020-01489-4</a>
  apa: Deuchert, A., &#38; Seiringer, R. (2020). Gross-Pitaevskii limit of a homogeneous
    Bose gas at positive temperature. <i>Archive for Rational Mechanics and Analysis</i>.
    Springer Nature. <a href="https://doi.org/10.1007/s00205-020-01489-4">https://doi.org/10.1007/s00205-020-01489-4</a>
  chicago: Deuchert, Andreas, and Robert Seiringer. “Gross-Pitaevskii Limit of a Homogeneous
    Bose Gas at Positive Temperature.” <i>Archive for Rational Mechanics and Analysis</i>.
    Springer Nature, 2020. <a href="https://doi.org/10.1007/s00205-020-01489-4">https://doi.org/10.1007/s00205-020-01489-4</a>.
  ieee: A. Deuchert and R. Seiringer, “Gross-Pitaevskii limit of a homogeneous Bose
    gas at positive temperature,” <i>Archive for Rational Mechanics and Analysis</i>,
    vol. 236, no. 6. Springer Nature, pp. 1217–1271, 2020.
  ista: Deuchert A, Seiringer R. 2020. Gross-Pitaevskii limit of a homogeneous Bose
    gas at positive temperature. Archive for Rational Mechanics and Analysis. 236(6),
    1217–1271.
  mla: Deuchert, Andreas, and Robert Seiringer. “Gross-Pitaevskii Limit of a Homogeneous
    Bose Gas at Positive Temperature.” <i>Archive for Rational Mechanics and Analysis</i>,
    vol. 236, no. 6, Springer Nature, 2020, pp. 1217–71, doi:<a href="https://doi.org/10.1007/s00205-020-01489-4">10.1007/s00205-020-01489-4</a>.
  short: A. Deuchert, R. Seiringer, Archive for Rational Mechanics and Analysis 236
    (2020) 1217–1271.
date_created: 2020-04-08T15:18:03Z
date_published: 2020-03-09T00:00:00Z
date_updated: 2023-09-05T14:18:49Z
day: '09'
ddc:
- '510'
department:
- _id: RoSe
doi: 10.1007/s00205-020-01489-4
ec_funded: 1
external_id:
  arxiv:
  - '1901.11363'
  isi:
  - '000519415000001'
file:
- access_level: open_access
  checksum: b645fb64bfe95bbc05b3eea374109a9c
  content_type: application/pdf
  creator: dernst
  date_created: 2020-11-20T13:17:42Z
  date_updated: 2020-11-20T13:17:42Z
  file_id: '8785'
  file_name: 2020_ArchRatMechanicsAnalysis_Deuchert.pdf
  file_size: 704633
  relation: main_file
  success: 1
file_date_updated: 2020-11-20T13:17:42Z
has_accepted_license: '1'
intvolume: '       236'
isi: 1
issue: '6'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
page: 1217-1271
project:
- _id: 25C6DC12-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '694227'
  name: Analysis of quantum many-body systems
- _id: B67AFEDC-15C9-11EA-A837-991A96BB2854
  name: IST Austria Open Access Fund
publication: Archive for Rational Mechanics and Analysis
publication_identifier:
  eissn:
  - 1432-0673
  issn:
  - 0003-9527
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Gross-Pitaevskii limit of a homogeneous Bose gas at positive temperature
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 236
year: '2020'
...
---
_id: '7651'
abstract:
- lang: eng
  text: The growth of snail shells can be described by simple mathematical rules.
    Variation in a few parameters can explain much of the diversity of shell shapes
    seen in nature. However, empirical studies of gastropod shell shape variation
    typically use geometric morphometric approaches, which do not capture this growth
    pattern. We have developed a way to infer a set of developmentally descriptive
    shape parameters based on three-dimensional logarithmic helicospiral growth and
    using landmarks from two-dimensional shell images as input. We demonstrate the
    utility of this approach, and compare it to the geometric morphometric approach,
    using a large set of Littorina saxatilis shells in which locally adapted populations
    differ in shape. Our method can be modified easily to make it applicable to a
    wide range of shell forms, which would allow for investigations of the similarities
    and differences between and within many different species of gastropods.
article_number: '20190721'
article_processing_charge: No
article_type: original
author:
- first_name: J.
  full_name: Larsson, J.
  last_name: Larsson
- first_name: Anja M
  full_name: Westram, Anja M
  id: 3C147470-F248-11E8-B48F-1D18A9856A87
  last_name: Westram
  orcid: 0000-0003-1050-4969
- first_name: S.
  full_name: Bengmark, S.
  last_name: Bengmark
- first_name: T.
  full_name: Lundh, T.
  last_name: Lundh
- first_name: R. K.
  full_name: Butlin, R. K.
  last_name: Butlin
citation:
  ama: Larsson J, Westram AM, Bengmark S, Lundh T, Butlin RK. A developmentally descriptive
    method for quantifying shape in gastropod shells. <i>Journal of The Royal Society
    Interface</i>. 2020;17(163). doi:<a href="https://doi.org/10.1098/rsif.2019.0721">10.1098/rsif.2019.0721</a>
  apa: Larsson, J., Westram, A. M., Bengmark, S., Lundh, T., &#38; Butlin, R. K. (2020).
    A developmentally descriptive method for quantifying shape in gastropod shells.
    <i>Journal of The Royal Society Interface</i>. The Royal Society. <a href="https://doi.org/10.1098/rsif.2019.0721">https://doi.org/10.1098/rsif.2019.0721</a>
  chicago: Larsson, J., Anja M Westram, S. Bengmark, T. Lundh, and R. K. Butlin. “A
    Developmentally Descriptive Method for Quantifying Shape in Gastropod Shells.”
    <i>Journal of The Royal Society Interface</i>. The Royal Society, 2020. <a href="https://doi.org/10.1098/rsif.2019.0721">https://doi.org/10.1098/rsif.2019.0721</a>.
  ieee: J. Larsson, A. M. Westram, S. Bengmark, T. Lundh, and R. K. Butlin, “A developmentally
    descriptive method for quantifying shape in gastropod shells,” <i>Journal of The
    Royal Society Interface</i>, vol. 17, no. 163. The Royal Society, 2020.
  ista: Larsson J, Westram AM, Bengmark S, Lundh T, Butlin RK. 2020. A developmentally
    descriptive method for quantifying shape in gastropod shells. Journal of The Royal
    Society Interface. 17(163), 20190721.
  mla: Larsson, J., et al. “A Developmentally Descriptive Method for Quantifying Shape
    in Gastropod Shells.” <i>Journal of The Royal Society Interface</i>, vol. 17,
    no. 163, 20190721, The Royal Society, 2020, doi:<a href="https://doi.org/10.1098/rsif.2019.0721">10.1098/rsif.2019.0721</a>.
  short: J. Larsson, A.M. Westram, S. Bengmark, T. Lundh, R.K. Butlin, Journal of
    The Royal Society Interface 17 (2020).
date_created: 2020-04-08T15:19:17Z
date_published: 2020-02-01T00:00:00Z
date_updated: 2021-01-12T08:14:41Z
day: '01'
ddc:
- '570'
department:
- _id: NiBa
doi: 10.1098/rsif.2019.0721
file:
- access_level: open_access
  checksum: 4eb102304402f5c56432516b84df86d6
  content_type: application/pdf
  creator: dernst
  date_created: 2020-04-14T12:31:16Z
  date_updated: 2020-07-14T12:48:01Z
  file_id: '7660'
  file_name: 2020_JournRoyalSociety_Larsson.pdf
  file_size: 1556190
  relation: main_file
file_date_updated: 2020-07-14T12:48:01Z
has_accepted_license: '1'
intvolume: '        17'
issue: '163'
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
publication: Journal of The Royal Society Interface
publication_identifier:
  eissn:
  - 1742-5662
  issn:
  - 1742-5689
publication_status: published
publisher: The Royal Society
quality_controlled: '1'
scopus_import: 1
status: public
title: A developmentally descriptive method for quantifying shape in gastropod shells
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 17
year: '2020'
...
---
_id: '7652'
abstract:
- lang: eng
  text: Organisms cope with change by taking advantage of transcriptional regulators.
    However, when faced with rare environments, the evolution of transcriptional regulators
    and their promoters may be too slow. Here, we investigate whether the intrinsic
    instability of gene duplication and amplification provides a generic alternative
    to canonical gene regulation. Using real-time monitoring of gene-copy-number mutations
    in Escherichia coli, we show that gene duplications and amplifications enable
    adaptation to fluctuating environments by rapidly generating copy-number and,
    therefore, expression-level polymorphisms. This amplification-mediated gene expression
    tuning (AMGET) occurs on timescales that are similar to canonical gene regulation
    and can respond to rapid environmental changes. Mathematical modelling shows that
    amplifications also tune gene expression in stochastic environments in which transcription-factor-based
    schemes are hard to evolve or maintain. The fleeting nature of gene amplifications
    gives rise to a generic population-level mechanism that relies on genetic heterogeneity
    to rapidly tune the expression of any gene, without leaving any genomic signature.
acknowledgement: We thank L. Hurst, N. Barton, M. Pleska, M. Steinrück, B. Kavcic
  and A. Staron for input on the manuscript, and To. Bergmiller and R. Chait for help
  with microfluidics experiments. I.T. is a recipient the OMV fellowship. R.G. is
  a recipient of a DOC (Doctoral Fellowship Programme of the Austrian Academy of Sciences)
  Fellowship of the Austrian Academy of Sciences.
article_processing_charge: No
article_type: original
author:
- first_name: Isabella
  full_name: Tomanek, Isabella
  id: 3981F020-F248-11E8-B48F-1D18A9856A87
  last_name: Tomanek
  orcid: 0000-0001-6197-363X
- first_name: Rok
  full_name: Grah, Rok
  id: 483E70DE-F248-11E8-B48F-1D18A9856A87
  last_name: Grah
  orcid: 0000-0003-2539-3560
- first_name: M.
  full_name: Lagator, M.
  last_name: Lagator
- first_name: A. M. C.
  full_name: Andersson, A. M. C.
  last_name: Andersson
- first_name: Jonathan P
  full_name: Bollback, Jonathan P
  id: 2C6FA9CC-F248-11E8-B48F-1D18A9856A87
  last_name: Bollback
  orcid: 0000-0002-4624-4612
- first_name: Gašper
  full_name: Tkačik, Gašper
  id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
  last_name: Tkačik
  orcid: 0000-0002-6699-1455
- first_name: Calin C
  full_name: Guet, Calin C
  id: 47F8433E-F248-11E8-B48F-1D18A9856A87
  last_name: Guet
  orcid: 0000-0001-6220-2052
citation:
  ama: Tomanek I, Grah R, Lagator M, et al. Gene amplification as a form of population-level
    gene expression regulation. <i>Nature Ecology &#38; Evolution</i>. 2020;4(4):612-625.
    doi:<a href="https://doi.org/10.1038/s41559-020-1132-7">10.1038/s41559-020-1132-7</a>
  apa: Tomanek, I., Grah, R., Lagator, M., Andersson, A. M. C., Bollback, J. P., Tkačik,
    G., &#38; Guet, C. C. (2020). Gene amplification as a form of population-level
    gene expression regulation. <i>Nature Ecology &#38; Evolution</i>. Springer Nature.
    <a href="https://doi.org/10.1038/s41559-020-1132-7">https://doi.org/10.1038/s41559-020-1132-7</a>
  chicago: Tomanek, Isabella, Rok Grah, M. Lagator, A. M. C. Andersson, Jonathan P
    Bollback, Gašper Tkačik, and Calin C Guet. “Gene Amplification as a Form of Population-Level
    Gene Expression Regulation.” <i>Nature Ecology &#38; Evolution</i>. Springer Nature,
    2020. <a href="https://doi.org/10.1038/s41559-020-1132-7">https://doi.org/10.1038/s41559-020-1132-7</a>.
  ieee: I. Tomanek <i>et al.</i>, “Gene amplification as a form of population-level
    gene expression regulation,” <i>Nature Ecology &#38; Evolution</i>, vol. 4, no.
    4. Springer Nature, pp. 612–625, 2020.
  ista: Tomanek I, Grah R, Lagator M, Andersson AMC, Bollback JP, Tkačik G, Guet CC.
    2020. Gene amplification as a form of population-level gene expression regulation.
    Nature Ecology &#38; Evolution. 4(4), 612–625.
  mla: Tomanek, Isabella, et al. “Gene Amplification as a Form of Population-Level
    Gene Expression Regulation.” <i>Nature Ecology &#38; Evolution</i>, vol. 4, no.
    4, Springer Nature, 2020, pp. 612–25, doi:<a href="https://doi.org/10.1038/s41559-020-1132-7">10.1038/s41559-020-1132-7</a>.
  short: I. Tomanek, R. Grah, M. Lagator, A.M.C. Andersson, J.P. Bollback, G. Tkačik,
    C.C. Guet, Nature Ecology &#38; Evolution 4 (2020) 612–625.
date_created: 2020-04-08T15:20:53Z
date_published: 2020-04-01T00:00:00Z
date_updated: 2024-03-25T23:30:20Z
day: '01'
ddc:
- '570'
department:
- _id: GaTk
- _id: CaGu
doi: 10.1038/s41559-020-1132-7
external_id:
  isi:
  - '000519008300005'
file:
- access_level: open_access
  checksum: ef3bbf42023e30b2c24a6278025d2040
  content_type: application/pdf
  creator: dernst
  date_created: 2020-10-09T09:56:01Z
  date_updated: 2020-10-09T09:56:01Z
  file_id: '8640'
  file_name: 2020_NatureEcolEvo_Tomanek.pdf
  file_size: 745242
  relation: main_file
  success: 1
file_date_updated: 2020-10-09T09:56:01Z
has_accepted_license: '1'
intvolume: '         4'
isi: 1
issue: '4'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Submitted Version
page: 612-625
project:
- _id: 267C84F4-B435-11E9-9278-68D0E5697425
  name: Biophysically realistic genotype-phenotype maps for regulatory networks
publication: Nature Ecology & Evolution
publication_identifier:
  issn:
  - 2397-334X
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
  link:
  - description: News on IST Homepage
    relation: press_release
    url: https://ist.ac.at/en/news/how-to-thrive-without-gene-regulation/
  record:
  - id: '8155'
    relation: dissertation_contains
    status: public
  - id: '7383'
    relation: research_data
    status: public
  - id: '7016'
    relation: research_data
    status: public
  - id: '8653'
    relation: used_in_publication
    status: public
scopus_import: '1'
status: public
title: Gene amplification as a form of population-level gene expression regulation
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 4
year: '2020'
...
---
_id: '7656'
abstract:
- lang: eng
  text: 'We propose that correlations among neurons are generically strong enough
    to organize neural activity patterns into a discrete set of clusters, which can
    each be viewed as a population codeword. Our reasoning starts with the analysis
    of retinal ganglion cell data using maximum entropy models, showing that the population
    is robustly in a frustrated, marginally sub-critical, or glassy, state. This leads
    to an argument that neural populations in many other brain areas might share this
    structure. Next, we use latent variable models to show that this glassy state
    possesses well-defined clusters of neural activity. Clusters have three appealing
    properties: (i) clusters exhibit error correction, i.e., they are reproducibly
    elicited by the same stimulus despite variability at the level of constituent
    neurons; (ii) clusters encode qualitatively different visual features than their
    constituent neurons; and (iii) clusters can be learned by downstream neural circuits
    in an unsupervised fashion. We hypothesize that these properties give rise to
    a “learnable” neural code which the cortical hierarchy uses to extract increasingly
    complex features without supervision or reinforcement.'
article_number: '20'
article_processing_charge: No
article_type: original
author:
- first_name: Michael J.
  full_name: Berry, Michael J.
  last_name: Berry
- first_name: Gašper
  full_name: Tkačik, Gašper
  id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
  last_name: Tkačik
  orcid: 0000-0002-6699-1455
citation:
  ama: 'Berry MJ, Tkačik G. Clustering of neural activity: A design principle for
    population codes. <i>Frontiers in Computational Neuroscience</i>. 2020;14. doi:<a
    href="https://doi.org/10.3389/fncom.2020.00020">10.3389/fncom.2020.00020</a>'
  apa: 'Berry, M. J., &#38; Tkačik, G. (2020). Clustering of neural activity: A design
    principle for population codes. <i>Frontiers in Computational Neuroscience</i>.
    Frontiers. <a href="https://doi.org/10.3389/fncom.2020.00020">https://doi.org/10.3389/fncom.2020.00020</a>'
  chicago: 'Berry, Michael J., and Gašper Tkačik. “Clustering of Neural Activity:
    A Design Principle for Population Codes.” <i>Frontiers in Computational Neuroscience</i>.
    Frontiers, 2020. <a href="https://doi.org/10.3389/fncom.2020.00020">https://doi.org/10.3389/fncom.2020.00020</a>.'
  ieee: 'M. J. Berry and G. Tkačik, “Clustering of neural activity: A design principle
    for population codes,” <i>Frontiers in Computational Neuroscience</i>, vol. 14.
    Frontiers, 2020.'
  ista: 'Berry MJ, Tkačik G. 2020. Clustering of neural activity: A design principle
    for population codes. Frontiers in Computational Neuroscience. 14, 20.'
  mla: 'Berry, Michael J., and Gašper Tkačik. “Clustering of Neural Activity: A Design
    Principle for Population Codes.” <i>Frontiers in Computational Neuroscience</i>,
    vol. 14, 20, Frontiers, 2020, doi:<a href="https://doi.org/10.3389/fncom.2020.00020">10.3389/fncom.2020.00020</a>.'
  short: M.J. Berry, G. Tkačik, Frontiers in Computational Neuroscience 14 (2020).
date_created: 2020-04-12T22:00:40Z
date_published: 2020-03-13T00:00:00Z
date_updated: 2023-08-18T10:30:11Z
day: '13'
ddc:
- '570'
department:
- _id: GaTk
doi: 10.3389/fncom.2020.00020
external_id:
  isi:
  - '000525543200001'
  pmid:
  - '32231528'
file:
- access_level: open_access
  checksum: 2b1da23823eae9cedbb42d701945b61e
  content_type: application/pdf
  creator: dernst
  date_created: 2020-04-14T12:20:39Z
  date_updated: 2020-07-14T12:48:01Z
  file_id: '7659'
  file_name: 2020_Frontiers_Berry.pdf
  file_size: 4082937
  relation: main_file
file_date_updated: 2020-07-14T12:48:01Z
has_accepted_license: '1'
intvolume: '        14'
isi: 1
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
pmid: 1
publication: Frontiers in Computational Neuroscience
publication_identifier:
  eissn:
  - '16625188'
publication_status: published
publisher: Frontiers
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Clustering of neural activity: A design principle for population codes'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 14
year: '2020'
...
---
_id: '7663'
abstract:
- lang: eng
  text: Wood, as the most abundant carbon dioxide storing bioresource, is currently
    driven beyond its traditional use through creative innovations and nanotechnology.
    For many properties the micro- and nanostructure plays a crucial role and one
    key challenge is control and detection of chemical and physical processes in the
    confined microstructure and nanopores of the wooden cell wall. In this study,
    correlative Raman and atomic force microscopy show high potential for tracking
    in situ molecular rearrangement of wood polymers during compression. More water
    molecules (interpreted as wider cellulose microfibril distances) and disentangling
    of hemicellulose chains are detected in the opened cell wall regions, whereas
    an increase of lignin is revealed in the compressed areas. These results support
    a new more “loose” cell wall model based on flexible lignin nanodomains and advance
    our knowledge of the molecular reorganization during deformation of wood for optimized
    processing and utilization.
article_processing_charge: No
article_type: original
author:
- first_name: Martin
  full_name: Felhofer, Martin
  last_name: Felhofer
- first_name: Peter
  full_name: Bock, Peter
  last_name: Bock
- first_name: Adya
  full_name: Singh, Adya
  last_name: Singh
- first_name: Batirtze
  full_name: Prats Mateu, Batirtze
  id: 299FE892-F248-11E8-B48F-1D18A9856A87
  last_name: Prats Mateu
- first_name: Ronald
  full_name: Zirbs, Ronald
  last_name: Zirbs
- first_name: Notburga
  full_name: Gierlinger, Notburga
  last_name: Gierlinger
citation:
  ama: Felhofer M, Bock P, Singh A, Prats Mateu B, Zirbs R, Gierlinger N. Wood deformation
    leads to rearrangement of molecules at the nanoscale. <i>Nano Letters</i>. 2020;20(4):2647-2653.
    doi:<a href="https://doi.org/10.1021/acs.nanolett.0c00205">10.1021/acs.nanolett.0c00205</a>
  apa: Felhofer, M., Bock, P., Singh, A., Prats Mateu, B., Zirbs, R., &#38; Gierlinger,
    N. (2020). Wood deformation leads to rearrangement of molecules at the nanoscale.
    <i>Nano Letters</i>. American Chemical Society. <a href="https://doi.org/10.1021/acs.nanolett.0c00205">https://doi.org/10.1021/acs.nanolett.0c00205</a>
  chicago: Felhofer, Martin, Peter Bock, Adya Singh, Batirtze Prats Mateu, Ronald
    Zirbs, and Notburga Gierlinger. “Wood Deformation Leads to Rearrangement of Molecules
    at the Nanoscale.” <i>Nano Letters</i>. American Chemical Society, 2020. <a href="https://doi.org/10.1021/acs.nanolett.0c00205">https://doi.org/10.1021/acs.nanolett.0c00205</a>.
  ieee: M. Felhofer, P. Bock, A. Singh, B. Prats Mateu, R. Zirbs, and N. Gierlinger,
    “Wood deformation leads to rearrangement of molecules at the nanoscale,” <i>Nano
    Letters</i>, vol. 20, no. 4. American Chemical Society, pp. 2647–2653, 2020.
  ista: Felhofer M, Bock P, Singh A, Prats Mateu B, Zirbs R, Gierlinger N. 2020. Wood
    deformation leads to rearrangement of molecules at the nanoscale. Nano Letters.
    20(4), 2647–2653.
  mla: Felhofer, Martin, et al. “Wood Deformation Leads to Rearrangement of Molecules
    at the Nanoscale.” <i>Nano Letters</i>, vol. 20, no. 4, American Chemical Society,
    2020, pp. 2647–53, doi:<a href="https://doi.org/10.1021/acs.nanolett.0c00205">10.1021/acs.nanolett.0c00205</a>.
  short: M. Felhofer, P. Bock, A. Singh, B. Prats Mateu, R. Zirbs, N. Gierlinger,
    Nano Letters 20 (2020) 2647–2653.
date_created: 2020-04-19T22:00:54Z
date_published: 2020-04-08T00:00:00Z
date_updated: 2023-08-21T06:12:09Z
day: '08'
ddc:
- '530'
department:
- _id: MaLo
doi: 10.1021/acs.nanolett.0c00205
external_id:
  isi:
  - '000526413400055'
  pmid:
  - '32196350'
file:
- access_level: open_access
  checksum: fe46146a9c4c620592a1932a8599069e
  content_type: application/pdf
  creator: dernst
  date_created: 2020-04-20T10:43:36Z
  date_updated: 2020-07-14T12:48:01Z
  file_id: '7667'
  file_name: 2020_NanoLetters_Felhofer.pdf
  file_size: 7108014
  relation: main_file
file_date_updated: 2020-07-14T12:48:01Z
has_accepted_license: '1'
intvolume: '        20'
isi: 1
issue: '4'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
page: 2647-2653
pmid: 1
publication: Nano Letters
publication_identifier:
  eissn:
  - '15306992'
publication_status: published
publisher: American Chemical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: Wood deformation leads to rearrangement of molecules at the nanoscale
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 20
year: '2020'
...
---
_id: '7664'
abstract:
- lang: eng
  text: Metabotropic γ-aminobutyric acid (GABAB) receptors contribute to the control
    of network activity and information processing in hippocampal circuits by regulating
    neuronal excitability and synaptic transmission. The dysfunction in the dentate
    gyrus (DG) has been implicated in Alzheimer´s disease (AD). Given the involvement
    of GABAB receptors in AD, to determine their subcellular localisation and possible
    alteration in granule cells of the DG in a mouse model of AD at 12 months of age,
    we used high-resolution immunoelectron microscopic analysis. Immunohistochemistry
    at the light microscopic level showed that the regional and cellular expression
    pattern of GABAB1 was similar in an AD model mouse expressing mutated human amyloid
    precursor protein and presenilin1 (APP/PS1) and in age-matched wild type mice.
    High-resolution immunoelectron microscopy revealed a distance-dependent gradient
    of immunolabelling for GABAB receptors, increasing from proximal to distal dendrites
    in both wild type and APP/PS1 mice. However, the overall density of GABAB receptors
    at the neuronal surface of these postsynaptic compartments of granule cells was
    significantly reduced in APP/PS1 mice. Parallel to this reduction in surface receptors,
    we found a significant increase in GABAB1 at cytoplasmic sites. GABAB receptors
    were also detected at presynaptic sites in the molecular layer of the DG. We also
    found a decrease in plasma membrane GABAB receptors in axon terminals contacting
    dendritic spines of granule cells, which was more pronounced in the outer than
    in the inner molecular layer. Altogether, our data showing post- and presynaptic
    reduction in surface GABAB receptors in the DG suggest the alteration of the GABAB-mediated
    modulation of excitability and synaptic transmission in granule cells, which may
    contribute to the cognitive dysfunctions in the APP/PS1 model of AD
article_number: '2459'
article_processing_charge: No
article_type: original
author:
- first_name: Alejandro
  full_name: Martín-Belmonte, Alejandro
  last_name: Martín-Belmonte
- first_name: Carolina
  full_name: Aguado, Carolina
  last_name: Aguado
- first_name: Rocío
  full_name: Alfaro-Ruíz, Rocío
  last_name: Alfaro-Ruíz
- first_name: Ana Esther
  full_name: Moreno-Martínez, Ana Esther
  last_name: Moreno-Martínez
- first_name: Luis
  full_name: De La Ossa, Luis
  last_name: De La Ossa
- first_name: José
  full_name: Martínez-Hernández, José
  last_name: Martínez-Hernández
- first_name: Alain
  full_name: Buisson, Alain
  last_name: Buisson
- first_name: Ryuichi
  full_name: Shigemoto, Ryuichi
  id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
  last_name: Shigemoto
  orcid: 0000-0001-8761-9444
- first_name: Yugo
  full_name: Fukazawa, Yugo
  last_name: Fukazawa
- first_name: Rafael
  full_name: Luján, Rafael
  last_name: Luján
citation:
  ama: Martín-Belmonte A, Aguado C, Alfaro-Ruíz R, et al. Density of GABAB receptors
    is reduced in granule cells of the hippocampus in a mouse model of Alzheimer’s
    disease. <i>International journal of molecular sciences</i>. 2020;21(7). doi:<a
    href="https://doi.org/10.3390/ijms21072459">10.3390/ijms21072459</a>
  apa: Martín-Belmonte, A., Aguado, C., Alfaro-Ruíz, R., Moreno-Martínez, A. E., De
    La Ossa, L., Martínez-Hernández, J., … Luján, R. (2020). Density of GABAB receptors
    is reduced in granule cells of the hippocampus in a mouse model of Alzheimer’s
    disease. <i>International Journal of Molecular Sciences</i>. MDPI. <a href="https://doi.org/10.3390/ijms21072459">https://doi.org/10.3390/ijms21072459</a>
  chicago: Martín-Belmonte, Alejandro, Carolina Aguado, Rocío Alfaro-Ruíz, Ana Esther
    Moreno-Martínez, Luis De La Ossa, José Martínez-Hernández, Alain Buisson, Ryuichi
    Shigemoto, Yugo Fukazawa, and Rafael Luján. “Density of GABAB Receptors Is Reduced
    in Granule Cells of the Hippocampus in a Mouse Model of Alzheimer’s Disease.”
    <i>International Journal of Molecular Sciences</i>. MDPI, 2020. <a href="https://doi.org/10.3390/ijms21072459">https://doi.org/10.3390/ijms21072459</a>.
  ieee: A. Martín-Belmonte <i>et al.</i>, “Density of GABAB receptors is reduced in
    granule cells of the hippocampus in a mouse model of Alzheimer’s disease,” <i>International
    journal of molecular sciences</i>, vol. 21, no. 7. MDPI, 2020.
  ista: Martín-Belmonte A, Aguado C, Alfaro-Ruíz R, Moreno-Martínez AE, De La Ossa
    L, Martínez-Hernández J, Buisson A, Shigemoto R, Fukazawa Y, Luján R. 2020. Density
    of GABAB receptors is reduced in granule cells of the hippocampus in a mouse model
    of Alzheimer’s disease. International journal of molecular sciences. 21(7), 2459.
  mla: Martín-Belmonte, Alejandro, et al. “Density of GABAB Receptors Is Reduced in
    Granule Cells of the Hippocampus in a Mouse Model of Alzheimer’s Disease.” <i>International
    Journal of Molecular Sciences</i>, vol. 21, no. 7, 2459, MDPI, 2020, doi:<a href="https://doi.org/10.3390/ijms21072459">10.3390/ijms21072459</a>.
  short: A. Martín-Belmonte, C. Aguado, R. Alfaro-Ruíz, A.E. Moreno-Martínez, L. De
    La Ossa, J. Martínez-Hernández, A. Buisson, R. Shigemoto, Y. Fukazawa, R. Luján,
    International Journal of Molecular Sciences 21 (2020).
date_created: 2020-04-19T22:00:55Z
date_published: 2020-04-02T00:00:00Z
date_updated: 2023-08-21T06:13:19Z
day: '02'
ddc:
- '570'
department:
- _id: RySh
doi: 10.3390/ijms21072459
external_id:
  isi:
  - '000535574200201'
  pmid:
  - '32252271'
file:
- access_level: open_access
  checksum: b9d2f1657d8c4a74b01a62b474d009b0
  content_type: application/pdf
  creator: dernst
  date_created: 2020-04-20T11:43:18Z
  date_updated: 2020-07-14T12:48:01Z
  file_id: '7669'
  file_name: 2020_JournMolecSciences_Martin_Belmonte.pdf
  file_size: 2941197
  relation: main_file
file_date_updated: 2020-07-14T12:48:01Z
has_accepted_license: '1'
intvolume: '        21'
isi: 1
issue: '7'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
pmid: 1
publication: International journal of molecular sciences
publication_identifier:
  eissn:
  - '14220067'
publication_status: published
publisher: MDPI
quality_controlled: '1'
scopus_import: '1'
status: public
title: Density of GABAB receptors is reduced in granule cells of the hippocampus in
  a mouse model of Alzheimer's disease
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 21
year: '2020'
...
---
_id: '7665'
abstract:
- lang: eng
  text: Acute brain slice preparation is a powerful experimental model for investigating
    the characteristics of synaptic function in the brain. Although brain tissue is
    usually cut at ice-cold temperature (CT) to facilitate slicing and avoid neuronal
    damage, exposure to CT causes molecular and architectural changes of synapses.
    To address these issues, we investigated ultrastructural and electrophysiological
    features of synapses in mouse acute cerebellar slices prepared at ice-cold and
    physiological temperature (PT). In the slices prepared at CT, we found significant
    spine loss and reconstruction, synaptic vesicle rearrangement and decrease in
    synaptic proteins, all of which were not detected in slices prepared at PT. Consistent
    with these structural findings, slices prepared at PT showed higher release probability.
    Furthermore, preparation at PT allows electrophysiological recording immediately
    after slicing resulting in higher detectability of long-term depression (LTD)
    after motor learning compared with that at CT. These results indicate substantial
    advantages of the slice preparation at PT for investigating synaptic functions
    in different physiological conditions.
article_number: '63'
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Kohgaku
  full_name: Eguchi, Kohgaku
  id: 2B7846DC-F248-11E8-B48F-1D18A9856A87
  last_name: Eguchi
  orcid: 0000-0002-6170-2546
- first_name: Philipp
  full_name: Velicky, Philipp
  id: 39BDC62C-F248-11E8-B48F-1D18A9856A87
  last_name: Velicky
  orcid: 0000-0002-2340-7431
- first_name: Elena
  full_name: Hollergschwandtner, Elena
  id: 3C054040-F248-11E8-B48F-1D18A9856A87
  last_name: Hollergschwandtner
- first_name: Makoto
  full_name: Itakura, Makoto
  last_name: Itakura
- first_name: Yugo
  full_name: Fukazawa, Yugo
  last_name: Fukazawa
- first_name: Johann G
  full_name: Danzl, Johann G
  id: 42EFD3B6-F248-11E8-B48F-1D18A9856A87
  last_name: Danzl
  orcid: 0000-0001-8559-3973
- first_name: Ryuichi
  full_name: Shigemoto, Ryuichi
  id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
  last_name: Shigemoto
  orcid: 0000-0001-8761-9444
citation:
  ama: Eguchi K, Velicky P, Saeckl E, et al. Advantages of acute brain slices prepared
    at physiological temperature in the characterization of synaptic functions. <i>Frontiers
    in Cellular Neuroscience</i>. 2020;14. doi:<a href="https://doi.org/10.3389/fncel.2020.00063">10.3389/fncel.2020.00063</a>
  apa: Eguchi, K., Velicky, P., Saeckl, E., Itakura, M., Fukazawa, Y., Danzl, J. G.,
    &#38; Shigemoto, R. (2020). Advantages of acute brain slices prepared at physiological
    temperature in the characterization of synaptic functions. <i>Frontiers in Cellular
    Neuroscience</i>. Frontiers Media. <a href="https://doi.org/10.3389/fncel.2020.00063">https://doi.org/10.3389/fncel.2020.00063</a>
  chicago: Eguchi, Kohgaku, Philipp Velicky, Elena Saeckl, Makoto Itakura, Yugo Fukazawa,
    Johann G Danzl, and Ryuichi Shigemoto. “Advantages of Acute Brain Slices Prepared
    at Physiological Temperature in the Characterization of Synaptic Functions.” <i>Frontiers
    in Cellular Neuroscience</i>. Frontiers Media, 2020. <a href="https://doi.org/10.3389/fncel.2020.00063">https://doi.org/10.3389/fncel.2020.00063</a>.
  ieee: K. Eguchi <i>et al.</i>, “Advantages of acute brain slices prepared at physiological
    temperature in the characterization of synaptic functions,” <i>Frontiers in Cellular
    Neuroscience</i>, vol. 14. Frontiers Media, 2020.
  ista: Eguchi K, Velicky P, Saeckl E, Itakura M, Fukazawa Y, Danzl JG, Shigemoto
    R. 2020. Advantages of acute brain slices prepared at physiological temperature
    in the characterization of synaptic functions. Frontiers in Cellular Neuroscience.
    14, 63.
  mla: Eguchi, Kohgaku, et al. “Advantages of Acute Brain Slices Prepared at Physiological
    Temperature in the Characterization of Synaptic Functions.” <i>Frontiers in Cellular
    Neuroscience</i>, vol. 14, 63, Frontiers Media, 2020, doi:<a href="https://doi.org/10.3389/fncel.2020.00063">10.3389/fncel.2020.00063</a>.
  short: K. Eguchi, P. Velicky, E. Saeckl, M. Itakura, Y. Fukazawa, J.G. Danzl, R.
    Shigemoto, Frontiers in Cellular Neuroscience 14 (2020).
date_created: 2020-04-19T22:00:55Z
date_published: 2020-03-19T00:00:00Z
date_updated: 2023-08-21T06:12:48Z
day: '19'
ddc:
- '570'
department:
- _id: JoDa
- _id: RySh
doi: 10.3389/fncel.2020.00063
ec_funded: 1
external_id:
  isi:
  - '000525582200001'
file:
- access_level: open_access
  checksum: 1c145123c6f8dc3e2e4bd5a66a1ad60e
  content_type: application/pdf
  creator: dernst
  date_created: 2020-04-20T10:59:49Z
  date_updated: 2020-07-14T12:48:01Z
  file_id: '7668'
  file_name: 2020_FrontiersCellularNeurosc_Eguchi.pdf
  file_size: 9227283
  relation: main_file
file_date_updated: 2020-07-14T12:48:01Z
has_accepted_license: '1'
intvolume: '        14'
isi: 1
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
project:
- _id: 2659CC84-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '793482'
  name: 'Ultrastructural analysis of phosphoinositides in nerve terminals: distribution,
    dynamics and physiological roles in synaptic transmission'
- _id: 25CA28EA-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '694539'
  name: 'In situ analysis of single channel subunit composition in neurons: physiological
    implication in synaptic plasticity and behaviour'
- _id: 265CB4D0-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: I03600
  name: Optical control of synaptic function via adhesion molecules
- _id: B67AFEDC-15C9-11EA-A837-991A96BB2854
  name: IST Austria Open Access Fund
publication: Frontiers in Cellular Neuroscience
publication_identifier:
  issn:
  - '16625102'
publication_status: published
publisher: Frontiers Media
quality_controlled: '1'
scopus_import: '1'
status: public
title: Advantages of acute brain slices prepared at physiological temperature in the
  characterization of synaptic functions
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 14
year: '2020'
...
---
_id: '7666'
abstract:
- lang: eng
  text: Generalizing the decomposition of a connected planar graph into a tree and
    a dual tree, we prove a combinatorial analog of the classic Helmholtz–Hodge decomposition
    of a smooth vector field. Specifically, we show that for every polyhedral complex,
    K, and every dimension, p, there is a partition of the set of p-cells into a maximal
    p-tree, a maximal p-cotree, and a collection of p-cells whose cardinality is the
    p-th reduced Betti number of K. Given an ordering of the p-cells, this tri-partition
    is unique, and it can be computed by a matrix reduction algorithm that also constructs
    canonical bases of cycle and boundary groups.
acknowledgement: This project has received funding from the European Research Council
  under the European Union’s Horizon 2020 research and innovation programme (Grant
  Agreement No. 78818 Alpha). It is also partially supported by the DFG Collaborative
  Research Center TRR 109, ‘Discretization in Geometry and Dynamics’, through Grant
  No. I02979-N35 of the Austrian Science Fund (FWF).
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Herbert
  full_name: Edelsbrunner, Herbert
  id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
  last_name: Edelsbrunner
  orcid: 0000-0002-9823-6833
- first_name: Katharina
  full_name: Ölsböck, Katharina
  id: 4D4AA390-F248-11E8-B48F-1D18A9856A87
  last_name: Ölsböck
  orcid: 0000-0002-4672-8297
citation:
  ama: Edelsbrunner H, Ölsböck K. Tri-partitions and bases of an ordered complex.
    <i>Discrete and Computational Geometry</i>. 2020;64:759-775. doi:<a href="https://doi.org/10.1007/s00454-020-00188-x">10.1007/s00454-020-00188-x</a>
  apa: Edelsbrunner, H., &#38; Ölsböck, K. (2020). Tri-partitions and bases of an
    ordered complex. <i>Discrete and Computational Geometry</i>. Springer Nature.
    <a href="https://doi.org/10.1007/s00454-020-00188-x">https://doi.org/10.1007/s00454-020-00188-x</a>
  chicago: Edelsbrunner, Herbert, and Katharina Ölsböck. “Tri-Partitions and Bases
    of an Ordered Complex.” <i>Discrete and Computational Geometry</i>. Springer Nature,
    2020. <a href="https://doi.org/10.1007/s00454-020-00188-x">https://doi.org/10.1007/s00454-020-00188-x</a>.
  ieee: H. Edelsbrunner and K. Ölsböck, “Tri-partitions and bases of an ordered complex,”
    <i>Discrete and Computational Geometry</i>, vol. 64. Springer Nature, pp. 759–775,
    2020.
  ista: Edelsbrunner H, Ölsböck K. 2020. Tri-partitions and bases of an ordered complex.
    Discrete and Computational Geometry. 64, 759–775.
  mla: Edelsbrunner, Herbert, and Katharina Ölsböck. “Tri-Partitions and Bases of
    an Ordered Complex.” <i>Discrete and Computational Geometry</i>, vol. 64, Springer
    Nature, 2020, pp. 759–75, doi:<a href="https://doi.org/10.1007/s00454-020-00188-x">10.1007/s00454-020-00188-x</a>.
  short: H. Edelsbrunner, K. Ölsböck, Discrete and Computational Geometry 64 (2020)
    759–775.
date_created: 2020-04-19T22:00:56Z
date_published: 2020-03-20T00:00:00Z
date_updated: 2023-08-21T06:13:48Z
day: '20'
ddc:
- '510'
department:
- _id: HeEd
doi: 10.1007/s00454-020-00188-x
ec_funded: 1
external_id:
  isi:
  - '000520918800001'
file:
- access_level: open_access
  checksum: f8cc96e497f00c38340b5dafe0cb91d7
  content_type: application/pdf
  creator: dernst
  date_created: 2020-11-20T13:22:21Z
  date_updated: 2020-11-20T13:22:21Z
  file_id: '8786'
  file_name: 2020_DiscreteCompGeo_Edelsbrunner.pdf
  file_size: 701673
  relation: main_file
  success: 1
file_date_updated: 2020-11-20T13:22:21Z
has_accepted_license: '1'
intvolume: '        64'
isi: 1
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
page: 759-775
project:
- _id: B67AFEDC-15C9-11EA-A837-991A96BB2854
  name: IST Austria Open Access Fund
- _id: 266A2E9E-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '788183'
  name: Alpha Shape Theory Extended
- _id: 2561EBF4-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: I02979-N35
  name: Persistence and stability of geometric complexes
publication: Discrete and Computational Geometry
publication_identifier:
  eissn:
  - '14320444'
  issn:
  - '01795376'
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Tri-partitions and bases of an ordered complex
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 64
year: '2020'
...
---
_id: '7672'
abstract:
- lang: eng
  text: Large overpotentials upon discharge and charge of Li-O2 cells have motivated
    extensive research into heterogeneous solid electrocatalysts or non-carbon electrodes
    with the aim to improve rate capability, round-trip efficiency and cycle life.
    These features are equally governed by parasitic reactions, which are now recognized
    to be caused by the highly reactive singlet oxygen (1O2). However, the link between
    the presence of electrocatalysts and 1O2 formation in metal-O2 cells is unknown.
    Here, we show that, compared to pristine carbon black electrodes, a representative
    selection of electrocatalysts or non-carbon electrodes (noble metal, transition
    metal compounds) may both slightly reduce or severely increase the 1O2 formation.
    The individual reaction steps, where the surfaces impact the 1O2 yield are deciphered,
    showing that 1O2 yield from superoxide disproportionation as well as the decomposition
    of trace H2O2 are sensitive to catalysts. Transition metal compounds in general
    are prone to increase 1O2.
acknowledgement: S.A.F. thanks the International Society of Electrochemistry for awarding
  the Tajima Prize 2019 “in recognition of outstanding re- searches on Li-Air batteries
  by the use of a range of in-situ elec- trochemical methods to achieve comprehensive
  understanding of the reactions taking place at the oxygen electrode”. This article
  is dedicated to the special issue of Electrochmica Acta associated with the awarding
  conference. S.A.F. is indebted to and the Austrian Federal Ministry of Science,
  Research and Economy and the Austrian Research Promotion Agency (grant No. 845364
  ) and the European Research Council (ERC) under the European Union’s Horizon 2020
  research and innovation programme (grant agreement No 636069). The authors thank
  J. Schlegl for manufacturing instrumentation, M. Winkler of Acib GmbH and G. Strohmeier
  for help with HPLC measurements, S. Eder for cyclic voltammetry measurements, and
  C. Slugovc for discussions and continuous support. We thank S. Borisov for access
  and advice with fluorescence measurements. We thank EL-Cell GmbH, Hamburg, Germany
  for providing the PAT-Cell-Press electrochemical cell.
article_number: '137175'
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Aleksej
  full_name: Samojlov, Aleksej
  last_name: Samojlov
- first_name: David
  full_name: Schuster, David
  last_name: Schuster
- first_name: Jürgen
  full_name: Kahr, Jürgen
  last_name: Kahr
- first_name: Stefan Alexander
  full_name: Freunberger, Stefan Alexander
  id: A8CA28E6-CE23-11E9-AD2D-EC27E6697425
  last_name: Freunberger
  orcid: 0000-0003-2902-5319
citation:
  ama: Samojlov A, Schuster D, Kahr J, Freunberger SA. Surface and catalyst driven
    singlet oxygen formation in Li-O2 cells. <i>Electrochimica Acta</i>. 2020;362(12).
    doi:<a href="https://doi.org/10.1016/j.electacta.2020.137175">10.1016/j.electacta.2020.137175</a>
  apa: Samojlov, A., Schuster, D., Kahr, J., &#38; Freunberger, S. A. (2020). Surface
    and catalyst driven singlet oxygen formation in Li-O2 cells. <i>Electrochimica
    Acta</i>. Elsevier. <a href="https://doi.org/10.1016/j.electacta.2020.137175">https://doi.org/10.1016/j.electacta.2020.137175</a>
  chicago: Samojlov, Aleksej, David Schuster, Jürgen Kahr, and Stefan Alexander Freunberger.
    “Surface and Catalyst Driven Singlet Oxygen Formation in Li-O2 Cells.” <i>Electrochimica
    Acta</i>. Elsevier, 2020. <a href="https://doi.org/10.1016/j.electacta.2020.137175">https://doi.org/10.1016/j.electacta.2020.137175</a>.
  ieee: A. Samojlov, D. Schuster, J. Kahr, and S. A. Freunberger, “Surface and catalyst
    driven singlet oxygen formation in Li-O2 cells,” <i>Electrochimica Acta</i>, vol.
    362, no. 12. Elsevier, 2020.
  ista: Samojlov A, Schuster D, Kahr J, Freunberger SA. 2020. Surface and catalyst
    driven singlet oxygen formation in Li-O2 cells. Electrochimica Acta. 362(12),
    137175.
  mla: Samojlov, Aleksej, et al. “Surface and Catalyst Driven Singlet Oxygen Formation
    in Li-O2 Cells.” <i>Electrochimica Acta</i>, vol. 362, no. 12, 137175, Elsevier,
    2020, doi:<a href="https://doi.org/10.1016/j.electacta.2020.137175">10.1016/j.electacta.2020.137175</a>.
  short: A. Samojlov, D. Schuster, J. Kahr, S.A. Freunberger, Electrochimica Acta
    362 (2020).
date_created: 2020-04-20T19:29:31Z
date_published: 2020-12-01T00:00:00Z
date_updated: 2023-08-21T06:14:21Z
day: '01'
ddc:
- '540'
department:
- _id: StFr
doi: 10.1016/j.electacta.2020.137175
external_id:
  isi:
  - '000582869700060'
file:
- access_level: open_access
  checksum: 1ab1aa2024d431e2a089ea336bc08298
  content_type: application/pdf
  creator: dernst
  date_created: 2020-10-01T13:20:45Z
  date_updated: 2020-10-01T13:20:45Z
  file_id: '8593'
  file_name: 2020_ElectrochimicaActa_Samojlov.pdf
  file_size: 1404030
  relation: main_file
  success: 1
file_date_updated: 2020-10-01T13:20:45Z
has_accepted_license: '1'
intvolume: '       362'
isi: 1
issue: '12'
language:
- iso: eng
month: '12'
oa: 1
oa_version: Published Version
publication: Electrochimica Acta
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Surface and catalyst driven singlet oxygen formation in Li-O2 cells
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 362
year: '2020'
...
---
_id: '7673'
abstract:
- lang: eng
  text: Combining drugs can improve the efficacy of treatments. However, predicting
    the effect of drug combinations is still challenging. The combined potency of
    drugs determines the drug interaction, which is classified as synergistic, additive,
    antagonistic, or suppressive. While probabilistic, non-mechanistic models exist,
    there is currently no biophysical model that can predict antibiotic interactions.
    Here, we present a physiologically relevant model of the combined action of antibiotics
    that inhibit protein synthesis by targeting the ribosome. This model captures
    the kinetics of antibiotic binding and transport, and uses bacterial growth laws
    to predict growth in the presence of antibiotic combinations. We find that this
    biophysical model can produce all drug interaction types except suppression. We
    show analytically that antibiotics which cannot bind to the ribosome simultaneously
    generally act as substitutes for one another, leading to additive drug interactions.
    Previously proposed null expectations for higher-order drug interactions follow
    as a limiting case of our model. We further extend the model to include the effects
    of direct physical or allosteric interactions between individual drugs on the
    ribosome. Notably, such direct interactions profoundly change the combined drug
    effect, depending on the kinetic parameters of the drugs used. The model makes
    additional predictions for the effects of resistance genes on drug interactions
    and for interactions between ribosome-targeting antibiotics and antibiotics with
    other targets. These findings enhance our understanding of the interplay between
    drug action and cell physiology and are a key step toward a general framework
    for predicting drug interactions.
article_processing_charge: No
author:
- first_name: Bor
  full_name: Kavcic, Bor
  id: 350F91D2-F248-11E8-B48F-1D18A9856A87
  last_name: Kavcic
  orcid: 0000-0001-6041-254X
- first_name: Gašper
  full_name: Tkačik, Gašper
  id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
  last_name: Tkačik
  orcid: 0000-0002-6699-1455
- first_name: Tobias
  full_name: Bollenbach, Tobias
  id: 3E6DB97A-F248-11E8-B48F-1D18A9856A87
  last_name: Bollenbach
  orcid: 0000-0003-4398-476X
citation:
  ama: Kavcic B, Tkačik G, Bollenbach MT. A minimal biophysical model of combined
    antibiotic action. <i>bioRxiv</i>. 2020. doi:<a href="https://doi.org/10.1101/2020.04.18.047886">10.1101/2020.04.18.047886</a>
  apa: Kavcic, B., Tkačik, G., &#38; Bollenbach, M. T. (2020). A minimal biophysical
    model of combined antibiotic action. <i>bioRxiv</i>. Cold Spring Harbor Laboratory.
    <a href="https://doi.org/10.1101/2020.04.18.047886">https://doi.org/10.1101/2020.04.18.047886</a>
  chicago: Kavcic, Bor, Gašper Tkačik, and Mark Tobias Bollenbach. “A Minimal Biophysical
    Model of Combined Antibiotic Action.” <i>BioRxiv</i>. Cold Spring Harbor Laboratory,
    2020. <a href="https://doi.org/10.1101/2020.04.18.047886">https://doi.org/10.1101/2020.04.18.047886</a>.
  ieee: B. Kavcic, G. Tkačik, and M. T. Bollenbach, “A minimal biophysical model of
    combined antibiotic action,” <i>bioRxiv</i>. Cold Spring Harbor Laboratory, 2020.
  ista: Kavcic B, Tkačik G, Bollenbach MT. 2020. A minimal biophysical model of combined
    antibiotic action. bioRxiv, <a href="https://doi.org/10.1101/2020.04.18.047886">10.1101/2020.04.18.047886</a>.
  mla: Kavcic, Bor, et al. “A Minimal Biophysical Model of Combined Antibiotic Action.”
    <i>BioRxiv</i>, Cold Spring Harbor Laboratory, 2020, doi:<a href="https://doi.org/10.1101/2020.04.18.047886">10.1101/2020.04.18.047886</a>.
  short: B. Kavcic, G. Tkačik, M.T. Bollenbach, BioRxiv (2020).
date_created: 2020-04-22T08:27:56Z
date_published: 2020-04-18T00:00:00Z
date_updated: 2024-03-25T23:30:05Z
day: '18'
department:
- _id: GaTk
doi: 10.1101/2020.04.18.047886
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: 'https://doi.org/10.1101/2020.04.18.047886 '
month: '04'
oa: 1
oa_version: Preprint
project:
- _id: 25E9AF9E-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: P27201-B22
  name: Revealing the mechanisms underlying drug interactions
- _id: 254E9036-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: P28844-B27
  name: Biophysics of information processing in gene regulation
publication: bioRxiv
publication_status: published
publisher: Cold Spring Harbor Laboratory
related_material:
  record:
  - id: '8997'
    relation: later_version
    status: public
  - id: '8657'
    relation: dissertation_contains
    status: public
status: public
title: A minimal biophysical model of combined antibiotic action
type: preprint
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2020'
...
---
_id: '7675'
abstract:
- lang: eng
  text: 'In prokaryotes, thermodynamic models of gene regulation provide a highly
    quantitative mapping from promoter sequences to gene expression levels that is
    compatible with in vivo and in vitro bio-physical measurements. Such concordance
    has not been achieved for models of enhancer function in eukaryotes. In equilibrium
    models, it is difficult to reconcile the reported short transcription factor (TF)
    residence times on the DNA with the high specificity of regulation. In non-equilibrium
    models, progress is difficult due to an explosion in the number of parameters.
    Here, we navigate this complexity by looking for minimal non-equilibrium enhancer
    models that yield desired regulatory phenotypes: low TF residence time, high specificity
    and tunable cooperativity. We find that a single extra parameter, interpretable
    as the “linking rate” by which bound TFs interact with Mediator components, enables
    our models to escape equilibrium bounds and access optimal regulatory phenotypes,
    while remaining consistent with the reported phenomenology and simple enough to
    be inferred from upcoming experiments. We further find that high specificity in
    non-equilibrium models is in a tradeoff with gene expression noise, predicting
    bursty dynamics — an experimentally-observed hallmark of eukaryotic transcription.
    By drastically reducing the vast parameter space to a much smaller subspace that
    optimally realizes biological function prior to inference from data, our normative
    approach holds promise for mathematical models in systems biology.'
article_processing_charge: No
author:
- first_name: Rok
  full_name: Grah, Rok
  id: 483E70DE-F248-11E8-B48F-1D18A9856A87
  last_name: Grah
  orcid: 0000-0003-2539-3560
- first_name: Benjamin
  full_name: Zoller, Benjamin
  last_name: Zoller
- first_name: Gašper
  full_name: Tkačik, Gašper
  id: 3D494DCA-F248-11E8-B48F-1D18A9856A87
  last_name: Tkačik
  orcid: 0000-0002-6699-1455
citation:
  ama: Grah R, Zoller B, Tkačik G. Normative models of enhancer function. <i>bioRxiv</i>.
    2020. doi:<a href="https://doi.org/10.1101/2020.04.08.029405">10.1101/2020.04.08.029405</a>
  apa: Grah, R., Zoller, B., &#38; Tkačik, G. (2020). Normative models of enhancer
    function. <i>bioRxiv</i>. Cold Spring Harbor Laboratory. <a href="https://doi.org/10.1101/2020.04.08.029405">https://doi.org/10.1101/2020.04.08.029405</a>
  chicago: Grah, Rok, Benjamin Zoller, and Gašper Tkačik. “Normative Models of Enhancer
    Function.” <i>BioRxiv</i>. Cold Spring Harbor Laboratory, 2020. <a href="https://doi.org/10.1101/2020.04.08.029405">https://doi.org/10.1101/2020.04.08.029405</a>.
  ieee: R. Grah, B. Zoller, and G. Tkačik, “Normative models of enhancer function,”
    <i>bioRxiv</i>. Cold Spring Harbor Laboratory, 2020.
  ista: Grah R, Zoller B, Tkačik G. 2020. Normative models of enhancer function. bioRxiv,
    <a href="https://doi.org/10.1101/2020.04.08.029405">10.1101/2020.04.08.029405</a>.
  mla: Grah, Rok, et al. “Normative Models of Enhancer Function.” <i>BioRxiv</i>,
    Cold Spring Harbor Laboratory, 2020, doi:<a href="https://doi.org/10.1101/2020.04.08.029405">10.1101/2020.04.08.029405</a>.
  short: R. Grah, B. Zoller, G. Tkačik, BioRxiv (2020).
date_created: 2020-04-23T10:12:51Z
date_published: 2020-04-09T00:00:00Z
date_updated: 2023-09-07T13:13:26Z
day: '09'
department:
- _id: CaGu
- _id: GaTk
doi: 10.1101/2020.04.08.029405
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: 'https://doi.org/10.1101/2020.04.08.029405 '
month: '04'
oa: 1
oa_version: Preprint
project:
- _id: 2665AAFE-B435-11E9-9278-68D0E5697425
  grant_number: RGP0034/2018
  name: Can evolution minimize spurious signaling crosstalk to reach optimal performance?
- _id: 267C84F4-B435-11E9-9278-68D0E5697425
  name: Biophysically realistic genotype-phenotype maps for regulatory networks
publication: bioRxiv
publication_status: published
publisher: Cold Spring Harbor Laboratory
related_material:
  record:
  - id: '8155'
    relation: dissertation_contains
    status: public
status: public
title: Normative models of enhancer function
type: preprint
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2020'
...
---
_id: '7680'
abstract:
- lang: eng
  text: "Proteins and their complex dynamic interactions regulate cellular mechanisms
    from sensing and transducing extracellular signals, to mediating genetic responses,
    and sustaining or changing cell morphology. To manipulate these protein-protein
    interactions (PPIs) that govern the behavior and fate of cells, synthetically
    constructed, genetically encoded tools provide the means to precisely target proteins
    of interest (POIs), and control their subcellular localization and activity in
    vitro and in vivo. Ideal synthetic tools react to an orthogonal cue, i.e. a trigger
    that does not activate any other endogenous process, thereby allowing manipulation
    of the POI alone.\r\nIn optogenetics, naturally occurring photosensory domain
    from plants, algae and bacteria are re-purposed and genetically fused to POIs.
    Illumination with light of a specific wavelength triggers a conformational change
    that can mediate PPIs, such as dimerization or oligomerization. By using light
    as a trigger, these tools can be activated with high spatial and temporal precision,
    on subcellular and millisecond scales. Chemogenetic tools consist of protein domains
    that recognize and bind small molecules. By genetic fusion to POIs, these domains
    can mediate PPIs upon addition of their specific ligands, which are often synthetically
    designed to provide highly specific interactions and exhibit good bioavailability.\r\nMost
    optogenetic tools to mediate PPIs are based on well-studied photoreceptors responding
    to red, blue or near-UV light, leaving a striking gap in the green band of the
    visible light spectrum. Among both optogenetic and chemogenetic tools, there is
    an abundance of methods to induce PPIs, but tools to disrupt them require UV illumination,
    rely on covalent linkage and subsequent enzymatic cleavage or initially result
    in protein clustering of unknown stoichiometry.\r\nThis work describes how the
    recently structurally and photochemically characterized green-light responsive
    cobalamin-binding domains (CBDs) from bacterial transcription factors were re-purposed
    to function as a green-light responsive optogenetic tool. In contrast to previously
    engineered optogenetic tools, CBDs do not induce PPI, but rather confer a PPI
    already upon expression, which can be rapidly disrupted by illumination. This
    was employed to mimic inhibition of constitutive activity of a growth factor receptor,
    and successfully implement for cell signalling in mammalian cells and in vivo
    to rescue development in zebrafish. This work further describes the development
    and application of a chemically induced de-dimerizer (CDD) based on a recently
    identified and structurally described bacterial oxyreductase. CDD forms a dimer
    upon expression in absence of its cofactor, the flavin derivative F420. Safety
    and of domain expression and ligand exposure are demonstrated in vitro and in
    vivo in zebrafish. The system is further applied to inhibit cell signalling output
    from a chimeric receptor upon F420 treatment.\r\nCBDs and CDD expand the repertoire
    of synthetic tools by providing novel mechanisms of mediating PPIs, and by recognizing
    previously not utilized cues. In the future, they can readily be combined with
    existing synthetic tools to functionally manipulate PPIs in vitro and in vivo."
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Stephanie
  full_name: Kainrath, Stephanie
  id: 32CFBA64-F248-11E8-B48F-1D18A9856A87
  last_name: Kainrath
citation:
  ama: Kainrath S. Synthetic tools for optogenetic and chemogenetic inhibition of
    cellular signals. 2020. doi:<a href="https://doi.org/10.15479/AT:ISTA:7680">10.15479/AT:ISTA:7680</a>
  apa: Kainrath, S. (2020). <i>Synthetic tools for optogenetic and chemogenetic inhibition
    of cellular signals</i>. Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/AT:ISTA:7680">https://doi.org/10.15479/AT:ISTA:7680</a>
  chicago: Kainrath, Stephanie. “Synthetic Tools for Optogenetic and Chemogenetic
    Inhibition of Cellular Signals.” Institute of Science and Technology Austria,
    2020. <a href="https://doi.org/10.15479/AT:ISTA:7680">https://doi.org/10.15479/AT:ISTA:7680</a>.
  ieee: S. Kainrath, “Synthetic tools for optogenetic and chemogenetic inhibition
    of cellular signals,” Institute of Science and Technology Austria, 2020.
  ista: Kainrath S. 2020. Synthetic tools for optogenetic and chemogenetic inhibition
    of cellular signals. Institute of Science and Technology Austria.
  mla: Kainrath, Stephanie. <i>Synthetic Tools for Optogenetic and Chemogenetic Inhibition
    of Cellular Signals</i>. Institute of Science and Technology Austria, 2020, doi:<a
    href="https://doi.org/10.15479/AT:ISTA:7680">10.15479/AT:ISTA:7680</a>.
  short: S. Kainrath, Synthetic Tools for Optogenetic and Chemogenetic Inhibition
    of Cellular Signals, Institute of Science and Technology Austria, 2020.
date_created: 2020-04-24T16:00:51Z
date_published: 2020-04-24T00:00:00Z
date_updated: 2023-09-22T09:20:10Z
day: '24'
ddc:
- '570'
degree_awarded: PhD
department:
- _id: CaGu
doi: 10.15479/AT:ISTA:7680
file:
- access_level: open_access
  checksum: fb9a4468eb27be92690728e35c823796
  content_type: application/pdf
  creator: stgingl
  date_created: 2020-04-28T11:19:21Z
  date_updated: 2021-10-31T23:30:05Z
  embargo: 2021-10-30
  file_id: '7692'
  file_name: Thesis_without-signatures_PDFA.pdf
  file_size: 3268017
  relation: main_file
- access_level: closed
  checksum: f6c80ca97104a631a328cb79a2c53493
  content_type: application/octet-stream
  creator: stgingl
  date_created: 2020-04-28T11:19:24Z
  date_updated: 2021-10-31T23:30:05Z
  embargo_to: open_access
  file_id: '7693'
  file_name: Thesis_without signatures.docx
  file_size: 5167703
  relation: source_file
file_date_updated: 2021-10-31T23:30:05Z
has_accepted_license: '1'
language:
- iso: eng
month: '04'
oa: 1
oa_version: None
page: '98'
publication_identifier:
  eissn:
  - 2663-337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '1028'
    relation: dissertation_contains
    status: public
status: public
supervisor:
- first_name: Harald L
  full_name: Janovjak, Harald L
  id: 33BA6C30-F248-11E8-B48F-1D18A9856A87
  last_name: Janovjak
  orcid: 0000-0002-8023-9315
title: Synthetic tools for optogenetic and chemogenetic inhibition of cellular signals
type: dissertation
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
year: '2020'
...
---
_id: '7683'
abstract:
- lang: eng
  text: For any free oriented Borel–Moore homology theory A, we construct an associative
    product on the A-theory of the stack of Higgs torsion sheaves over a projective
    curve C. We show that the resulting algebra AHa0C admits a natural shuffle presentation,
    and prove it is faithful when A is replaced with usual Borel–Moore homology groups.
    We also introduce moduli spaces of stable triples, heavily inspired by Nakajima
    quiver varieties, whose A-theory admits an AHa0C-action. These triples can be
    interpreted as certain sheaves on PC(ωC⊕OC). In particular, we obtain an action
    of AHa0C on the cohomology of Hilbert schemes of points on T∗C.
article_number: '30'
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Sasha
  full_name: Minets, Sasha
  id: 3E7C5304-F248-11E8-B48F-1D18A9856A87
  last_name: Minets
  orcid: 0000-0003-3883-1806
citation:
  ama: Minets S. Cohomological Hall algebras for Higgs torsion sheaves, moduli of
    triples and sheaves on surfaces. <i>Selecta Mathematica, New Series</i>. 2020;26(2).
    doi:<a href="https://doi.org/10.1007/s00029-020-00553-x">10.1007/s00029-020-00553-x</a>
  apa: Minets, S. (2020). Cohomological Hall algebras for Higgs torsion sheaves, moduli
    of triples and sheaves on surfaces. <i>Selecta Mathematica, New Series</i>. Springer
    Nature. <a href="https://doi.org/10.1007/s00029-020-00553-x">https://doi.org/10.1007/s00029-020-00553-x</a>
  chicago: Minets, Sasha. “Cohomological Hall Algebras for Higgs Torsion Sheaves,
    Moduli of Triples and Sheaves on Surfaces.” <i>Selecta Mathematica, New Series</i>.
    Springer Nature, 2020. <a href="https://doi.org/10.1007/s00029-020-00553-x">https://doi.org/10.1007/s00029-020-00553-x</a>.
  ieee: S. Minets, “Cohomological Hall algebras for Higgs torsion sheaves, moduli
    of triples and sheaves on surfaces,” <i>Selecta Mathematica, New Series</i>, vol.
    26, no. 2. Springer Nature, 2020.
  ista: Minets S. 2020. Cohomological Hall algebras for Higgs torsion sheaves, moduli
    of triples and sheaves on surfaces. Selecta Mathematica, New Series. 26(2), 30.
  mla: Minets, Sasha. “Cohomological Hall Algebras for Higgs Torsion Sheaves, Moduli
    of Triples and Sheaves on Surfaces.” <i>Selecta Mathematica, New Series</i>, vol.
    26, no. 2, 30, Springer Nature, 2020, doi:<a href="https://doi.org/10.1007/s00029-020-00553-x">10.1007/s00029-020-00553-x</a>.
  short: S. Minets, Selecta Mathematica, New Series 26 (2020).
date_created: 2020-04-26T22:00:44Z
date_published: 2020-04-15T00:00:00Z
date_updated: 2023-08-21T06:14:58Z
day: '15'
ddc:
- '510'
department:
- _id: TaHa
doi: 10.1007/s00029-020-00553-x
external_id:
  arxiv:
  - '1801.01429'
  isi:
  - '000526036400001'
file:
- access_level: open_access
  checksum: 2368c4662629b4759295eb365323b2ad
  content_type: application/pdf
  creator: dernst
  date_created: 2020-04-28T10:57:58Z
  date_updated: 2020-07-14T12:48:02Z
  file_id: '7690'
  file_name: 2020_SelectaMathematica_Minets.pdf
  file_size: 792469
  relation: main_file
file_date_updated: 2020-07-14T12:48:02Z
has_accepted_license: '1'
intvolume: '        26'
isi: 1
issue: '2'
language:
- iso: eng
month: '04'
oa: 1
oa_version: Published Version
project:
- _id: B67AFEDC-15C9-11EA-A837-991A96BB2854
  name: IST Austria Open Access Fund
publication: Selecta Mathematica, New Series
publication_identifier:
  eissn:
  - '14209020'
  issn:
  - '10221824'
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Cohomological Hall algebras for Higgs torsion sheaves, moduli of triples and
  sheaves on surfaces
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 26
year: '2020'
...
---
_id: '7684'
article_processing_charge: No
article_type: original
author:
- first_name: Igor
  full_name: Gridchyn, Igor
  id: 4B60654C-F248-11E8-B48F-1D18A9856A87
  last_name: Gridchyn
  orcid: 0000-0002-1807-1929
- first_name: Philipp
  full_name: Schönenberger, Philipp
  id: 3B9D816C-F248-11E8-B48F-1D18A9856A87
  last_name: Schönenberger
- first_name: Joseph
  full_name: O'Neill, Joseph
  id: 426376DC-F248-11E8-B48F-1D18A9856A87
  last_name: O'Neill
- first_name: Jozsef L
  full_name: Csicsvari, Jozsef L
  id: 3FA14672-F248-11E8-B48F-1D18A9856A87
  last_name: Csicsvari
  orcid: 0000-0002-5193-4036
citation:
  ama: Gridchyn I, Schönenberger P, O’Neill J, Csicsvari JL. Assembly-specific disruption
    of hippocampal replay leads to selective memory deficit. <i>Neuron</i>. 2020;106(2):291-300.e6.
    doi:<a href="https://doi.org/10.1016/j.neuron.2020.01.021">10.1016/j.neuron.2020.01.021</a>
  apa: Gridchyn, I., Schönenberger, P., O’Neill, J., &#38; Csicsvari, J. L. (2020).
    Assembly-specific disruption of hippocampal replay leads to selective memory deficit.
    <i>Neuron</i>. Elsevier. <a href="https://doi.org/10.1016/j.neuron.2020.01.021">https://doi.org/10.1016/j.neuron.2020.01.021</a>
  chicago: Gridchyn, Igor, Philipp Schönenberger, Joseph O’Neill, and Jozsef L Csicsvari.
    “Assembly-Specific Disruption of Hippocampal Replay Leads to Selective Memory
    Deficit.” <i>Neuron</i>. Elsevier, 2020. <a href="https://doi.org/10.1016/j.neuron.2020.01.021">https://doi.org/10.1016/j.neuron.2020.01.021</a>.
  ieee: I. Gridchyn, P. Schönenberger, J. O’Neill, and J. L. Csicsvari, “Assembly-specific
    disruption of hippocampal replay leads to selective memory deficit,” <i>Neuron</i>,
    vol. 106, no. 2. Elsevier, p. 291–300.e6, 2020.
  ista: Gridchyn I, Schönenberger P, O’Neill J, Csicsvari JL. 2020. Assembly-specific
    disruption of hippocampal replay leads to selective memory deficit. Neuron. 106(2),
    291–300.e6.
  mla: Gridchyn, Igor, et al. “Assembly-Specific Disruption of Hippocampal Replay
    Leads to Selective Memory Deficit.” <i>Neuron</i>, vol. 106, no. 2, Elsevier,
    2020, p. 291–300.e6, doi:<a href="https://doi.org/10.1016/j.neuron.2020.01.021">10.1016/j.neuron.2020.01.021</a>.
  short: I. Gridchyn, P. Schönenberger, J. O’Neill, J.L. Csicsvari, Neuron 106 (2020)
    291–300.e6.
date_created: 2020-04-26T22:00:45Z
date_published: 2020-04-22T00:00:00Z
date_updated: 2023-08-21T06:15:31Z
day: '22'
department:
- _id: JoCs
doi: 10.1016/j.neuron.2020.01.021
ec_funded: 1
external_id:
  isi:
  - '000528268200013'
  pmid:
  - '32070475'
intvolume: '       106'
isi: 1
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1016/j.neuron.2020.01.021
month: '04'
oa: 1
oa_version: Published Version
page: 291-300.e6
pmid: 1
project:
- _id: 257A4776-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '281511'
  name: Memory-related information processing in neuronal circuits of the hippocampus
    and entorhinal cortex
publication: Neuron
publication_identifier:
  eissn:
  - '10974199'
  issn:
  - '08966273'
publication_status: published
publisher: Elsevier
quality_controlled: '1'
related_material:
  link:
  - description: News on IST Homepage
    relation: press_release
    url: https://ist.ac.at/en/news/librarian-of-memory/
scopus_import: '1'
status: public
title: Assembly-specific disruption of hippocampal replay leads to selective memory
  deficit
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 106
year: '2020'
...
---
_id: '7686'
abstract:
- lang: eng
  text: 'The agricultural green revolution spectacularly enhanced crop yield and lodging
    resistance with modified DELLA-mediated gibberellin signaling. However, this was
    achieved at the expense of reduced nitrogen-use efficiency (NUE). Recently, Wu
    et al. revealed novel gibberellin signaling that provides a blueprint for improving
    tillering and NUE in Green Revolution varieties (GRVs). '
article_processing_charge: No
article_type: original
author:
- first_name: Huidan
  full_name: Xue, Huidan
  last_name: Xue
- first_name: Yuzhou
  full_name: Zhang, Yuzhou
  id: 3B6137F2-F248-11E8-B48F-1D18A9856A87
  last_name: Zhang
  orcid: 0000-0003-2627-6956
- first_name: Guanghui
  full_name: Xiao, Guanghui
  last_name: Xiao
citation:
  ama: 'Xue H, Zhang Y, Xiao G. Neo-gibberellin signaling: Guiding the next generation
    of the green revolution. <i>Trends in Plant Science</i>. 2020;25(6):520-522. doi:<a
    href="https://doi.org/10.1016/j.tplants.2020.04.001">10.1016/j.tplants.2020.04.001</a>'
  apa: 'Xue, H., Zhang, Y., &#38; Xiao, G. (2020). Neo-gibberellin signaling: Guiding
    the next generation of the green revolution. <i>Trends in Plant Science</i>. Elsevier.
    <a href="https://doi.org/10.1016/j.tplants.2020.04.001">https://doi.org/10.1016/j.tplants.2020.04.001</a>'
  chicago: 'Xue, Huidan, Yuzhou Zhang, and Guanghui Xiao. “Neo-Gibberellin Signaling:
    Guiding the next Generation of the Green Revolution.” <i>Trends in Plant Science</i>.
    Elsevier, 2020. <a href="https://doi.org/10.1016/j.tplants.2020.04.001">https://doi.org/10.1016/j.tplants.2020.04.001</a>.'
  ieee: 'H. Xue, Y. Zhang, and G. Xiao, “Neo-gibberellin signaling: Guiding the next
    generation of the green revolution,” <i>Trends in Plant Science</i>, vol. 25,
    no. 6. Elsevier, pp. 520–522, 2020.'
  ista: 'Xue H, Zhang Y, Xiao G. 2020. Neo-gibberellin signaling: Guiding the next
    generation of the green revolution. Trends in Plant Science. 25(6), 520–522.'
  mla: 'Xue, Huidan, et al. “Neo-Gibberellin Signaling: Guiding the next Generation
    of the Green Revolution.” <i>Trends in Plant Science</i>, vol. 25, no. 6, Elsevier,
    2020, pp. 520–22, doi:<a href="https://doi.org/10.1016/j.tplants.2020.04.001">10.1016/j.tplants.2020.04.001</a>.'
  short: H. Xue, Y. Zhang, G. Xiao, Trends in Plant Science 25 (2020) 520–522.
date_created: 2020-04-26T22:00:46Z
date_published: 2020-06-01T00:00:00Z
date_updated: 2023-08-21T06:16:01Z
day: '01'
department:
- _id: JiFr
doi: 10.1016/j.tplants.2020.04.001
external_id:
  isi:
  - '000533518400003'
  pmid:
  - '32407691'
intvolume: '        25'
isi: 1
issue: '6'
language:
- iso: eng
month: '06'
oa_version: None
page: 520-522
pmid: 1
publication: Trends in Plant Science
publication_identifier:
  issn:
  - 1360-1385
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Neo-gibberellin signaling: Guiding the next generation of the green revolution'
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 25
year: '2020'
...
---
_id: '7687'
abstract:
- lang: eng
  text: A working group, which was established within the Network of Repository Managers  (RepManNet),  has  dealt  with  common  certifications  for  repositories.  In
    addition,  current  requirements  of  the  research  funding  agencies  FWF  and  EU  were
    also taken into account. The Core Trust Seal was examined in more detail. For
    this purpose,  a  questionnaire  was  sent  to  those  organizations  that  are  already  certified
    with CTS in Austria. The answers were summarized and evaluated anonymously. It
    is recommended to go for a repository certification. Moreover, the development
    of a DINI certificate in Austria is strongly suggested.
- lang: ger
  text: ' Eine Arbeitsgruppe, die im Rahmen des Netzwerks für RepositorienmanagerInnen
    (RepManNet) entstanden ist, hat sich mit gängigen Zertifizierungen für Repositorien
    beschäftigt. Weiters wurden aktuelle Vorgaben der Forschungsförderer FWF und EU
    herangezogen. Das Core Trust Seal wurde genauer betrachtet. Hierfür  wurden jenen  Organisationen,  die  in  Österreich  bereits  mit  CTS  zertifiziert
    sind, ein Fragebogen übermittelt. Die Antworten wurden anonymisiert zusammengefasst
    und ausgewertet. Plädiert wird für eine Zertifizierung von Repositorien und die
    Entwicklung einer DINI-Zertifizierung in Österreich.'
article_processing_charge: No
article_type: original
author:
- first_name: Doris
  full_name: Ernst, Doris
  id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
  last_name: Ernst
  orcid: 0000-0002-2354-0195
- first_name: Gertraud
  full_name: Novotny, Gertraud
  last_name: Novotny
- first_name: Eva Maria
  full_name: Schönher, Eva Maria
  last_name: Schönher
citation:
  ama: Ernst D, Novotny G, Schönher EM. (Core Trust) Seal your repository! <i>Mitteilungen
    der Vereinigung Österreichischer Bibliothekarinnen und Bibliothekare</i>. 2020;73(1):46-59.
    doi:<a href="https://doi.org/10.31263/voebm.v73i1.3491">10.31263/voebm.v73i1.3491</a>
  apa: Ernst, D., Novotny, G., &#38; Schönher, E. M. (2020). (Core Trust) Seal your
    repository! <i>Mitteilungen der Vereinigung Österreichischer Bibliothekarinnen
    und Bibliothekare</i>. Vereinigung Osterreichischer Bibliothekarinnen und Bibliothekare.
    <a href="https://doi.org/10.31263/voebm.v73i1.3491">https://doi.org/10.31263/voebm.v73i1.3491</a>
  chicago: Ernst, Doris, Gertraud Novotny, and Eva Maria Schönher. “(Core Trust) Seal
    your repository!” <i>Mitteilungen der Vereinigung Österreichischer Bibliothekarinnen
    und Bibliothekare</i>. Vereinigung Osterreichischer Bibliothekarinnen und Bibliothekare,
    2020. <a href="https://doi.org/10.31263/voebm.v73i1.3491">https://doi.org/10.31263/voebm.v73i1.3491</a>.
  ieee: D. Ernst, G. Novotny, and E. M. Schönher, “(Core Trust) Seal your repository!,”
    <i>Mitteilungen der Vereinigung Österreichischer Bibliothekarinnen und Bibliothekare</i>,
    vol. 73, no. 1. Vereinigung Osterreichischer Bibliothekarinnen und Bibliothekare,
    pp. 46–59, 2020.
  ista: Ernst D, Novotny G, Schönher EM. 2020. (Core Trust) Seal your repository!
    Mitteilungen der Vereinigung Österreichischer Bibliothekarinnen und Bibliothekare.
    73(1), 46–59.
  mla: Ernst, Doris, et al. “(Core Trust) Seal your repository!” <i>Mitteilungen der
    Vereinigung Österreichischer Bibliothekarinnen und Bibliothekare</i>, vol. 73,
    no. 1, Vereinigung Osterreichischer Bibliothekarinnen und Bibliothekare, 2020,
    pp. 46–59, doi:<a href="https://doi.org/10.31263/voebm.v73i1.3491">10.31263/voebm.v73i1.3491</a>.
  short: D. Ernst, G. Novotny, E.M. Schönher, Mitteilungen der Vereinigung Österreichischer
    Bibliothekarinnen und Bibliothekare 73 (2020) 46–59.
date_created: 2020-04-28T08:37:38Z
date_published: 2020-04-28T00:00:00Z
date_updated: 2024-02-27T13:41:03Z
day: '28'
ddc:
- '020'
department:
- _id: E-Lib
doi: 10.31263/voebm.v73i1.3491
file:
- access_level: open_access
  checksum: fee784f15a489deb7def6ccf8c5bf8c3
  content_type: application/pdf
  creator: dernst
  date_created: 2020-06-17T10:50:13Z
  date_updated: 2023-04-03T09:17:25Z
  file_id: '7970'
  file_name: 2020_VOEB_Ernst.pdf
  file_size: 579291
  relation: main_file
file_date_updated: 2023-04-03T09:17:25Z
has_accepted_license: '1'
intvolume: '        73'
issue: '1'
language:
- iso: ger
month: '04'
oa: 1
oa_version: Published Version
page: 46-59
popular_science: '1'
publication: Mitteilungen der Vereinigung Österreichischer Bibliothekarinnen und Bibliothekare
publication_identifier:
  issn:
  - 1022-2588
publication_status: published
publisher: Vereinigung Osterreichischer Bibliothekarinnen und Bibliothekare
scopus_import: '1'
status: public
title: (Core Trust) Seal your repository!
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 73
year: '2020'
...
---
_id: '7689'
abstract:
- lang: eng
  text: "These are the supplementary research data to the publication \"Zero field
    splitting of heavy-hole states in quantum dots\". All matrix files have the same
    format. Within each column the bias voltage is changed. Each column corresponds
    to either a different gate voltage or magnetic field. The voltage values are given
    in mV, the current values in pA. Find a specific description in the included Readme
    file.\r\n"
article_processing_charge: No
author:
- first_name: Georgios
  full_name: Katsaros, Georgios
  id: 38DB5788-F248-11E8-B48F-1D18A9856A87
  last_name: Katsaros
  orcid: 0000-0001-8342-202X
citation:
  ama: Katsaros G. Supplementary data for “Zero field splitting of heavy-hole states
    in quantum dots.” 2020. doi:<a href="https://doi.org/10.15479/AT:ISTA:7689">10.15479/AT:ISTA:7689</a>
  apa: Katsaros, G. (2020). Supplementary data for “Zero field splitting of heavy-hole
    states in quantum dots.” Institute of Science and Technology Austria. <a href="https://doi.org/10.15479/AT:ISTA:7689">https://doi.org/10.15479/AT:ISTA:7689</a>
  chicago: Katsaros, Georgios. “Supplementary Data for ‘Zero Field Splitting of Heavy-Hole
    States in Quantum Dots.’” Institute of Science and Technology Austria, 2020. <a
    href="https://doi.org/10.15479/AT:ISTA:7689">https://doi.org/10.15479/AT:ISTA:7689</a>.
  ieee: G. Katsaros, “Supplementary data for ‘Zero field splitting of heavy-hole states
    in quantum dots.’” Institute of Science and Technology Austria, 2020.
  ista: Katsaros G. 2020. Supplementary data for ‘Zero field splitting of heavy-hole
    states in quantum dots’, Institute of Science and Technology Austria, <a href="https://doi.org/10.15479/AT:ISTA:7689">10.15479/AT:ISTA:7689</a>.
  mla: Katsaros, Georgios. <i>Supplementary Data for “Zero Field Splitting of Heavy-Hole
    States in Quantum Dots.”</i> Institute of Science and Technology Austria, 2020,
    doi:<a href="https://doi.org/10.15479/AT:ISTA:7689">10.15479/AT:ISTA:7689</a>.
  short: G. Katsaros, (2020).
contributor:
- contributor_type: contact_person
  first_name: Georgios
  id: 38DB5788-F248-11E8-B48F-1D18A9856A87
  last_name: Katsaros
date_created: 2020-05-01T15:14:46Z
date_published: 2020-05-01T00:00:00Z
date_updated: 2024-02-21T12:44:02Z
day: '01'
ddc:
- '530'
department:
- _id: GeKa
doi: 10.15479/AT:ISTA:7689
ec_funded: 1
file:
- access_level: open_access
  checksum: d23c0cb9e2d19e14e2f902b88b97c05d
  content_type: application/x-zip-compressed
  creator: gkatsaro
  date_created: 2020-05-01T15:13:28Z
  date_updated: 2020-07-14T12:48:02Z
  file_id: '7786'
  file_name: DOI_ZeroFieldSplitting.zip
  file_size: 5514403
  relation: main_file
file_date_updated: 2020-07-14T12:48:02Z
has_accepted_license: '1'
license: https://creativecommons.org/publicdomain/zero/1.0/
month: '05'
oa: 1
oa_version: Published Version
project:
- _id: 237E5020-32DE-11EA-91FC-C7463DDC885E
  call_identifier: H2020
  grant_number: '862046'
  name: TOPOLOGICALLY PROTECTED AND SCALABLE QUANTUM BITS
- _id: 237B3DA4-32DE-11EA-91FC-C7463DDC885E
  call_identifier: FWF
  grant_number: P32235
  name: Towards scalable hut wire quantum devices
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '8203'
    relation: used_in_publication
    status: public
status: public
title: Supplementary data for "Zero field splitting of heavy-hole states in quantum
  dots"
tmp:
  image: /images/cc_0.png
  legal_code_url: https://creativecommons.org/publicdomain/zero/1.0/legalcode
  name: Creative Commons Public Domain Dedication (CC0 1.0)
  short: CC0 (1.0)
type: research_data
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2020'
...
---
_id: '7695'
abstract:
- lang: eng
  text: The TPLATE complex (TPC) is a key endocytic adaptor protein complex in plants.
    TPC in Arabidopsis (Arabidopsis thaliana) contains six evolutionarily conserved
    subunits and two plant-specific subunits, AtEH1/Pan1 and AtEH2/Pan1, although
    cytoplasmic proteins are not associated with the hexameric subcomplex in the cytoplasm.
    To investigate the dynamic assembly of the octameric TPC at the plasma membrane
    (PM), we performed state-of-the-art dual-color live cell imaging at physiological
    and lowered temperatures. Lowering the temperature slowed down endocytosis, thereby
    enhancing the temporal resolution of the differential recruitment of endocytic
    components. Under both normal and lowered temperature conditions, the core TPC
    subunit TPLATE and the AtEH/Pan1 proteins exhibited simultaneous recruitment at
    the PM. These results, together with co-localization analysis of different TPC
    subunits, allow us to conclude that TPC in plant cells is not recruited to the
    PM sequentially but as an octameric complex.
article_processing_charge: No
article_type: original
author:
- first_name: J
  full_name: Wang, J
  last_name: Wang
- first_name: E
  full_name: Mylle, E
  last_name: Mylle
- first_name: Alexander J
  full_name: Johnson, Alexander J
  id: 46A62C3A-F248-11E8-B48F-1D18A9856A87
  last_name: Johnson
  orcid: 0000-0002-2739-8843
- first_name: N
  full_name: Besbrugge, N
  last_name: Besbrugge
- first_name: G
  full_name: De Jaeger, G
  last_name: De Jaeger
- first_name: Jiří
  full_name: Friml, Jiří
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
- first_name: R
  full_name: Pleskot, R
  last_name: Pleskot
- first_name: D
  full_name: van Damme, D
  last_name: van Damme
citation:
  ama: Wang J, Mylle E, Johnson AJ, et al. High temporal resolution reveals simultaneous
    plasma membrane recruitment of TPLATE complex subunits. <i>Plant Physiology</i>.
    2020;183(3):986-997. doi:<a href="https://doi.org/10.1104/pp.20.00178">10.1104/pp.20.00178</a>
  apa: Wang, J., Mylle, E., Johnson, A. J., Besbrugge, N., De Jaeger, G., Friml, J.,
    … van Damme, D. (2020). High temporal resolution reveals simultaneous plasma membrane
    recruitment of TPLATE complex subunits. <i>Plant Physiology</i>. American Society
    of Plant Biologists. <a href="https://doi.org/10.1104/pp.20.00178">https://doi.org/10.1104/pp.20.00178</a>
  chicago: Wang, J, E Mylle, Alexander J Johnson, N Besbrugge, G De Jaeger, Jiří Friml,
    R Pleskot, and D van Damme. “High Temporal Resolution Reveals Simultaneous Plasma
    Membrane Recruitment of TPLATE Complex Subunits.” <i>Plant Physiology</i>. American
    Society of Plant Biologists, 2020. <a href="https://doi.org/10.1104/pp.20.00178">https://doi.org/10.1104/pp.20.00178</a>.
  ieee: J. Wang <i>et al.</i>, “High temporal resolution reveals simultaneous plasma
    membrane recruitment of TPLATE complex subunits,” <i>Plant Physiology</i>, vol.
    183, no. 3. American Society of Plant Biologists, pp. 986–997, 2020.
  ista: Wang J, Mylle E, Johnson AJ, Besbrugge N, De Jaeger G, Friml J, Pleskot R,
    van Damme D. 2020. High temporal resolution reveals simultaneous plasma membrane
    recruitment of TPLATE complex subunits. Plant Physiology. 183(3), 986–997.
  mla: Wang, J., et al. “High Temporal Resolution Reveals Simultaneous Plasma Membrane
    Recruitment of TPLATE Complex Subunits.” <i>Plant Physiology</i>, vol. 183, no.
    3, American Society of Plant Biologists, 2020, pp. 986–97, doi:<a href="https://doi.org/10.1104/pp.20.00178">10.1104/pp.20.00178</a>.
  short: J. Wang, E. Mylle, A.J. Johnson, N. Besbrugge, G. De Jaeger, J. Friml, R.
    Pleskot, D. van Damme, Plant Physiology 183 (2020) 986–997.
date_created: 2020-04-29T15:23:00Z
date_published: 2020-07-01T00:00:00Z
date_updated: 2023-09-05T12:20:02Z
day: '01'
department:
- _id: JiFr
doi: 10.1104/pp.20.00178
external_id:
  isi:
  - '000550682000018'
  pmid:
  - '32321842'
intvolume: '       183'
isi: 1
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1101/2020.02.13.948109
month: '07'
oa: 1
oa_version: Preprint
page: 986-997
pmid: 1
project:
- _id: 26538374-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: I03630
  name: Molecular mechanisms of endocytic cargo recognition in plants
publication: Plant Physiology
publication_identifier:
  eissn:
  - 1532-2548
  issn:
  - 0032-0889
publication_status: published
publisher: American Society of Plant Biologists
quality_controlled: '1'
scopus_import: '1'
status: public
title: High temporal resolution reveals simultaneous plasma membrane recruitment of
  TPLATE complex subunits
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 183
year: '2020'
...
---
_id: '7697'
abstract:
- lang: eng
  text: "* Morphogenesis and adaptive tropic growth in plants depend on gradients
    of the phytohormone auxin, mediated by the membrane‐based PIN‐FORMED (PIN) auxin
    transporters. PINs localize to a particular side of the plasma membrane (PM) or
    to the endoplasmic reticulum (ER) to directionally transport auxin and maintain
    intercellular and intracellular auxin homeostasis, respectively. However, the
    molecular cues that confer their diverse cellular localizations remain largely
    unknown.\r\n* In this study, we systematically swapped the domains between ER‐
    and PM‐localized PIN proteins, as well as between apical and basal PM‐localized
    PINs from Arabidopsis thaliana , to shed light on why PIN family members with
    similar topological structures reside at different membrane compartments within
    cells.\r\n* Our results show that not only do the N‐ and C‐terminal transmembrane
    domains (TMDs) and central hydrophilic loop contribute to their differential subcellular
    localizations and cellular polarity, but that the pairwise‐matched N‐ and C‐terminal
    TMDs resulting from intramolecular domain–domain coevolution are also crucial
    for their divergent patterns of localization.\r\n* These findings illustrate the
    complexity of the evolutionary path of PIN proteins in acquiring their plethora
    of developmental functions and adaptive growth in plants."
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Yuzhou
  full_name: Zhang, Yuzhou
  id: 3B6137F2-F248-11E8-B48F-1D18A9856A87
  last_name: Zhang
  orcid: 0000-0003-2627-6956
- first_name: Corinna
  full_name: Hartinger, Corinna
  id: AEFB2266-8ABF-11EA-AA39-812C3623CBE4
  last_name: Hartinger
  orcid: 0000-0003-1618-2737
- first_name: Xiaojuan
  full_name: Wang, Xiaojuan
  last_name: Wang
- first_name: Jiří
  full_name: Friml, Jiří
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
citation:
  ama: Zhang Y, Hartinger C, Wang X, Friml J. Directional auxin fluxes in plants by
    intramolecular domain‐domain co‐evolution of PIN auxin transporters. <i>New Phytologist</i>.
    2020;227(5):1406-1416. doi:<a href="https://doi.org/10.1111/nph.16629">10.1111/nph.16629</a>
  apa: Zhang, Y., Hartinger, C., Wang, X., &#38; Friml, J. (2020). Directional auxin
    fluxes in plants by intramolecular domain‐domain co‐evolution of PIN auxin transporters.
    <i>New Phytologist</i>. Wiley. <a href="https://doi.org/10.1111/nph.16629">https://doi.org/10.1111/nph.16629</a>
  chicago: Zhang, Yuzhou, Corinna Hartinger, Xiaojuan Wang, and Jiří Friml. “Directional
    Auxin Fluxes in Plants by Intramolecular Domain‐domain Co‐evolution of PIN Auxin
    Transporters.” <i>New Phytologist</i>. Wiley, 2020. <a href="https://doi.org/10.1111/nph.16629">https://doi.org/10.1111/nph.16629</a>.
  ieee: Y. Zhang, C. Hartinger, X. Wang, and J. Friml, “Directional auxin fluxes in
    plants by intramolecular domain‐domain co‐evolution of PIN auxin transporters,”
    <i>New Phytologist</i>, vol. 227, no. 5. Wiley, pp. 1406–1416, 2020.
  ista: Zhang Y, Hartinger C, Wang X, Friml J. 2020. Directional auxin fluxes in plants
    by intramolecular domain‐domain co‐evolution of PIN auxin transporters. New Phytologist.
    227(5), 1406–1416.
  mla: Zhang, Yuzhou, et al. “Directional Auxin Fluxes in Plants by Intramolecular
    Domain‐domain Co‐evolution of PIN Auxin Transporters.” <i>New Phytologist</i>,
    vol. 227, no. 5, Wiley, 2020, pp. 1406–16, doi:<a href="https://doi.org/10.1111/nph.16629">10.1111/nph.16629</a>.
  short: Y. Zhang, C. Hartinger, X. Wang, J. Friml, New Phytologist 227 (2020) 1406–1416.
date_created: 2020-04-30T08:43:29Z
date_published: 2020-09-01T00:00:00Z
date_updated: 2023-09-05T15:46:04Z
day: '01'
ddc:
- '580'
department:
- _id: JiFr
doi: 10.1111/nph.16629
ec_funded: 1
external_id:
  isi:
  - '000534092400001'
  pmid:
  - '32350870'
file:
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  checksum: 8e8150dbbba8cb65b72f81d1f0864b8b
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  creator: dernst
  date_created: 2020-11-24T12:19:38Z
  date_updated: 2020-11-24T12:19:38Z
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file_date_updated: 2020-11-24T12:19:38Z
has_accepted_license: '1'
intvolume: '       227'
isi: 1
issue: '5'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
page: 1406-1416
pmid: 1
project:
- _id: 261099A6-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '742985'
  name: Tracing Evolution of Auxin Transport and Polarity in Plants
- _id: 26538374-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: I03630
  name: Molecular mechanisms of endocytic cargo recognition in plants
- _id: 25681D80-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '291734'
  name: International IST Postdoc Fellowship Programme
publication: New Phytologist
publication_identifier:
  eissn:
  - 1469-8137
  issn:
  - 0028-646X
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Directional auxin fluxes in plants by intramolecular domain‐domain co‐evolution
  of PIN auxin transporters
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 227
year: '2020'
...
---
_id: '5681'
abstract:
- lang: eng
  text: 'We introduce dynamically warping grids for adaptive liquid simulation. Our
    primary contributions are a strategy for dynamically deforming regular grids over
    the course of a simulation and a method for efficiently utilizing these deforming
    grids for liquid simulation. Prior work has shown that unstructured grids are
    very effective for adaptive fluid simulations. However, unstructured grids often
    lead to complicated implementations and a poor cache hit rate due to inconsistent
    memory access. Regular grids, on the other hand, provide a fast, fixed memory
    access pattern and straightforward implementation. Our method combines the advantages
    of both: we leverage the simplicity of regular grids while still achieving practical
    and controllable spatial adaptivity. We demonstrate that our method enables adaptive
    simulations that are fast, flexible, and robust to null-space issues. At the same
    time, our method is simple to implement and takes advantage of existing highly-tuned
    algorithms.'
acknowledged_ssus:
- _id: ScienComp
acknowledgement: This work was partially supported by JSPS Grant-in-Aid forYoung Scientists
  (Start-up) 16H07410, the ERC StartingGrantsrealFlow(StG-2015-637014) andBigSplash(StG-2014-638176).
  This research was supported by the Scientific Ser-vice Units (SSU) of IST Austria
  through resources providedby Scientific Computing. We would like to express my grati-tude
  to Nobuyuki Umetani and Tomas Skrivan for insight-ful discussion.
article_processing_charge: No
article_type: original
author:
- first_name: Ibayashi
  full_name: Hikaru, Ibayashi
  last_name: Hikaru
- first_name: Christopher J
  full_name: Wojtan, Christopher J
  id: 3C61F1D2-F248-11E8-B48F-1D18A9856A87
  last_name: Wojtan
  orcid: 0000-0001-6646-5546
- first_name: Nils
  full_name: Thuerey, Nils
  last_name: Thuerey
- first_name: Takeo
  full_name: Igarashi, Takeo
  last_name: Igarashi
- first_name: Ryoichi
  full_name: Ando, Ryoichi
  last_name: Ando
citation:
  ama: Hikaru I, Wojtan C, Thuerey N, Igarashi T, Ando R. Simulating liquids on dynamically
    warping grids. <i>IEEE Transactions on Visualization and Computer Graphics</i>.
    2020;26(6):2288-2302. doi:<a href="https://doi.org/10.1109/TVCG.2018.2883628">10.1109/TVCG.2018.2883628</a>
  apa: Hikaru, I., Wojtan, C., Thuerey, N., Igarashi, T., &#38; Ando, R. (2020). Simulating
    liquids on dynamically warping grids. <i>IEEE Transactions on Visualization and
    Computer Graphics</i>. IEEE. <a href="https://doi.org/10.1109/TVCG.2018.2883628">https://doi.org/10.1109/TVCG.2018.2883628</a>
  chicago: Hikaru, Ibayashi, Chris Wojtan, Nils Thuerey, Takeo Igarashi, and Ryoichi
    Ando. “Simulating Liquids on Dynamically Warping Grids.” <i>IEEE Transactions
    on Visualization and Computer Graphics</i>. IEEE, 2020. <a href="https://doi.org/10.1109/TVCG.2018.2883628">https://doi.org/10.1109/TVCG.2018.2883628</a>.
  ieee: I. Hikaru, C. Wojtan, N. Thuerey, T. Igarashi, and R. Ando, “Simulating liquids
    on dynamically warping grids,” <i>IEEE Transactions on Visualization and Computer
    Graphics</i>, vol. 26, no. 6. IEEE, pp. 2288–2302, 2020.
  ista: Hikaru I, Wojtan C, Thuerey N, Igarashi T, Ando R. 2020. Simulating liquids
    on dynamically warping grids. IEEE Transactions on Visualization and Computer
    Graphics. 26(6), 2288–2302.
  mla: Hikaru, Ibayashi, et al. “Simulating Liquids on Dynamically Warping Grids.”
    <i>IEEE Transactions on Visualization and Computer Graphics</i>, vol. 26, no.
    6, IEEE, 2020, pp. 2288–302, doi:<a href="https://doi.org/10.1109/TVCG.2018.2883628">10.1109/TVCG.2018.2883628</a>.
  short: I. Hikaru, C. Wojtan, N. Thuerey, T. Igarashi, R. Ando, IEEE Transactions
    on Visualization and Computer Graphics 26 (2020) 2288–2302.
date_created: 2018-12-16T22:59:21Z
date_published: 2020-06-01T00:00:00Z
date_updated: 2023-09-18T09:30:01Z
day: '01'
ddc:
- '006'
department:
- _id: ChWo
doi: 10.1109/TVCG.2018.2883628
external_id:
  isi:
  - '000532295600014'
  pmid:
  - '30507534'
file:
- access_level: open_access
  checksum: 8d4c55443a0ee335bb5bb652de503042
  content_type: application/pdf
  creator: wojtan
  date_created: 2020-10-08T08:34:53Z
  date_updated: 2020-10-08T08:34:53Z
  file_id: '8626'
  file_name: preprint.pdf
  file_size: 21910098
  relation: main_file
  success: 1
file_date_updated: 2020-10-08T08:34:53Z
has_accepted_license: '1'
intvolume: '        26'
isi: 1
issue: '6'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Submitted Version
page: 2288-2302
pmid: 1
publication: IEEE Transactions on Visualization and Computer Graphics
publication_identifier:
  eissn:
  - '19410506'
  issn:
  - '10772626'
publication_status: published
publisher: IEEE
quality_controlled: '1'
scopus_import: '1'
status: public
title: Simulating liquids on dynamically warping grids
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 26
year: '2020'
...
