---
_id: '9253'
abstract:
- lang: eng
text: In March 2020, the Austrian government introduced a widespread lock-down in
response to the COVID-19 pandemic. Based on subjective impressions and anecdotal
evidence, Austrian public and private life came to a sudden halt. Here we assess
the effect of the lock-down quantitatively for all regions in Austria and present
an analysis of daily changes of human mobility throughout Austria using near-real-time
anonymized mobile phone data. We describe an efficient data aggregation pipeline
and analyze the mobility by quantifying mobile-phone traffic at specific point
of interests (POIs), analyzing individual trajectories and investigating the cluster
structure of the origin-destination graph. We found a reduction of commuters at
Viennese metro stations of over 80% and the number of devices with a radius of
gyration of less than 500 m almost doubled. The results of studying crowd-movement
behavior highlight considerable changes in the structure of mobility networks,
revealed by a higher modularity and an increase from 12 to 20 detected communities.
We demonstrate the relevance of mobility data for epidemiological studies by showing
a significant correlation of the outflow from the town of Ischgl (an early COVID-19
hotspot) and the reported COVID-19 cases with an 8-day time lag. This research
indicates that mobile phone usage data permits the moment-by-moment quantification
of mobility behavior for a whole country. We emphasize the need to improve the
availability of such data in anonymized form to empower rapid response to combat
COVID-19 and future pandemics.
article_processing_charge: No
arxiv: 1
author:
- first_name: Georg
full_name: Heiler, Georg
last_name: Heiler
- first_name: Tobias
full_name: Reisch, Tobias
last_name: Reisch
- first_name: Jan
full_name: Hurt, Jan
last_name: Hurt
- first_name: Mohammad
full_name: Forghani, Mohammad
last_name: Forghani
- first_name: Aida
full_name: Omani, Aida
last_name: Omani
- first_name: Allan
full_name: Hanbury, Allan
last_name: Hanbury
- first_name: Farid
full_name: Karimipour, Farid
id: 2A2BCDC4-CF62-11E9-BE5E-3B1EE6697425
last_name: Karimipour
orcid: 0000-0001-6746-4174
citation:
ama: 'Heiler G, Reisch T, Hurt J, et al. Country-wide mobility changes observed
using mobile phone data during COVID-19 pandemic. In: 2020 IEEE International
Conference on Big Data. IEEE; 2021:3123-3132. doi:10.1109/bigdata50022.2020.9378374'
apa: 'Heiler, G., Reisch, T., Hurt, J., Forghani, M., Omani, A., Hanbury, A., &
Karimipour, F. (2021). Country-wide mobility changes observed using mobile phone
data during COVID-19 pandemic. In 2020 IEEE International Conference on Big
Data (pp. 3123–3132). Atlanta, GA, United States: IEEE. https://doi.org/10.1109/bigdata50022.2020.9378374'
chicago: Heiler, Georg, Tobias Reisch, Jan Hurt, Mohammad Forghani, Aida Omani,
Allan Hanbury, and Farid Karimipour. “Country-Wide Mobility Changes Observed Using
Mobile Phone Data during COVID-19 Pandemic.” In 2020 IEEE International Conference
on Big Data, 3123–32. IEEE, 2021. https://doi.org/10.1109/bigdata50022.2020.9378374.
ieee: G. Heiler et al., “Country-wide mobility changes observed using mobile
phone data during COVID-19 pandemic,” in 2020 IEEE International Conference
on Big Data, Atlanta, GA, United States, 2021, pp. 3123–3132.
ista: 'Heiler G, Reisch T, Hurt J, Forghani M, Omani A, Hanbury A, Karimipour F.
2021. Country-wide mobility changes observed using mobile phone data during COVID-19
pandemic. 2020 IEEE International Conference on Big Data. Big Data: International
Conference on Big Data, 3123–3132.'
mla: Heiler, Georg, et al. “Country-Wide Mobility Changes Observed Using Mobile
Phone Data during COVID-19 Pandemic.” 2020 IEEE International Conference on
Big Data, IEEE, 2021, pp. 3123–32, doi:10.1109/bigdata50022.2020.9378374.
short: G. Heiler, T. Reisch, J. Hurt, M. Forghani, A. Omani, A. Hanbury, F. Karimipour,
in:, 2020 IEEE International Conference on Big Data, IEEE, 2021, pp. 3123–3132.
conference:
end_date: 2020-12-13
location: Atlanta, GA, United States
name: 'Big Data: International Conference on Big Data'
start_date: 2020-12-10
date_created: 2021-03-21T11:34:07Z
date_published: 2021-03-19T00:00:00Z
date_updated: 2023-08-07T14:00:13Z
day: '19'
department:
- _id: HeEd
doi: 10.1109/bigdata50022.2020.9378374
external_id:
arxiv:
- '2008.10064'
isi:
- '000662554703032'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/2008.10064
month: '03'
oa: 1
oa_version: Preprint
page: 3123-3132
publication: 2020 IEEE International Conference on Big Data
publication_identifier:
isbn:
- '9781728162515'
publication_status: published
publisher: IEEE
quality_controlled: '1'
scopus_import: '1'
status: public
title: Country-wide mobility changes observed using mobile phone data during COVID-19
pandemic
type: conference
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
year: '2021'
...
---
_id: '9254'
abstract:
- lang: eng
text: 'Auxin is a key regulator of plant growth and development. Local auxin biosynthesis
and intercellular transport generates regional gradients in the root that are
instructive for processes such as specification of developmental zones that maintain
root growth and tropic responses. Here we present a toolbox to study auxin-mediated
root development that features: (i) the ability to control auxin synthesis with
high spatio-temporal resolution and (ii) single-cell nucleus tracking and morphokinetic
analysis infrastructure. Integration of these two features enables cutting-edge
analysis of root development at single-cell resolution based on morphokinetic
parameters under normal growth conditions and during cell-type-specific induction
of auxin biosynthesis. We show directional auxin flow in the root and refine the
contributions of key players in this process. In addition, we determine the quantitative
kinetics of Arabidopsis root meristem skewing, which depends on local auxin gradients
but does not require PIN2 and AUX1 auxin transporter activities. Beyond the mechanistic
insights into root development, the tools developed here will enable biologists
to study kinetics and morphology of various critical processes at the single cell-level
in whole organisms.'
acknowledgement: This work was supported by grants from the Israel Science Foundation
(2378/19 to E.S.), the Joint NSFC-ISF Research Grant (3419/20 to E.S. and Z.D.),
the Human Frontier Science Program (HFSP—LIY000540/2020 to E.S.), the European Research
Council Starting Grant (757683- RobustHormoneTrans to E.S.), PBC postdoctoral fellowships
(to Y.H. and M.O.), NIH (GM114660 to Y.Z.), Breast Cancer Research Foundation (BCRF
to I.T.).
article_number: '1657'
article_processing_charge: No
article_type: original
author:
- first_name: Yangjie
full_name: Hu, Yangjie
last_name: Hu
- first_name: Moutasem
full_name: Omary, Moutasem
last_name: Omary
- first_name: Yun
full_name: Hu, Yun
last_name: Hu
- first_name: Ohad
full_name: Doron, Ohad
last_name: Doron
- first_name: Lukas
full_name: Hörmayer, Lukas
id: 2EEE7A2A-F248-11E8-B48F-1D18A9856A87
last_name: Hörmayer
- first_name: Qingguo
full_name: Chen, Qingguo
last_name: Chen
- first_name: Or
full_name: Megides, Or
last_name: Megides
- first_name: Ori
full_name: Chekli, Ori
last_name: Chekli
- first_name: Zhaojun
full_name: Ding, Zhaojun
last_name: Ding
- first_name: Jiří
full_name: Friml, Jiří
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Yunde
full_name: Zhao, Yunde
last_name: Zhao
- first_name: Ilan
full_name: Tsarfaty, Ilan
last_name: Tsarfaty
- first_name: Eilon
full_name: Shani, Eilon
last_name: Shani
citation:
ama: Hu Y, Omary M, Hu Y, et al. Cell kinetics of auxin transport and activity in
Arabidopsis root growth and skewing. Nature Communications. 2021;12. doi:10.1038/s41467-021-21802-3
apa: Hu, Y., Omary, M., Hu, Y., Doron, O., Hörmayer, L., Chen, Q., … Shani, E. (2021).
Cell kinetics of auxin transport and activity in Arabidopsis root growth and skewing.
Nature Communications. Springer Nature. https://doi.org/10.1038/s41467-021-21802-3
chicago: Hu, Yangjie, Moutasem Omary, Yun Hu, Ohad Doron, Lukas Hörmayer, Qingguo
Chen, Or Megides, et al. “Cell Kinetics of Auxin Transport and Activity in Arabidopsis
Root Growth and Skewing.” Nature Communications. Springer Nature, 2021.
https://doi.org/10.1038/s41467-021-21802-3.
ieee: Y. Hu et al., “Cell kinetics of auxin transport and activity in Arabidopsis
root growth and skewing,” Nature Communications, vol. 12. Springer Nature,
2021.
ista: Hu Y, Omary M, Hu Y, Doron O, Hörmayer L, Chen Q, Megides O, Chekli O, Ding
Z, Friml J, Zhao Y, Tsarfaty I, Shani E. 2021. Cell kinetics of auxin transport
and activity in Arabidopsis root growth and skewing. Nature Communications. 12,
1657.
mla: Hu, Yangjie, et al. “Cell Kinetics of Auxin Transport and Activity in Arabidopsis
Root Growth and Skewing.” Nature Communications, vol. 12, 1657, Springer
Nature, 2021, doi:10.1038/s41467-021-21802-3.
short: Y. Hu, M. Omary, Y. Hu, O. Doron, L. Hörmayer, Q. Chen, O. Megides, O. Chekli,
Z. Ding, J. Friml, Y. Zhao, I. Tsarfaty, E. Shani, Nature Communications 12 (2021).
date_created: 2021-03-21T23:01:19Z
date_published: 2021-03-12T00:00:00Z
date_updated: 2023-08-07T14:17:55Z
day: '12'
ddc:
- '580'
department:
- _id: JiFr
doi: 10.1038/s41467-021-21802-3
external_id:
isi:
- '000630419400048'
pmid:
- '33712581'
file:
- access_level: open_access
checksum: e1022f3aee349853ded2b2b3e092362d
content_type: application/pdf
creator: dernst
date_created: 2021-03-22T11:18:58Z
date_updated: 2021-03-22T11:18:58Z
file_id: '9275'
file_name: 2021_NatureComm_Hu.pdf
file_size: 8602096
relation: main_file
success: 1
file_date_updated: 2021-03-22T11:18:58Z
has_accepted_license: '1'
intvolume: ' 12'
isi: 1
language:
- iso: eng
license: https://creativecommons.org/licenses/by/4.0/
month: '03'
oa: 1
oa_version: Published Version
pmid: 1
publication: Nature Communications
publication_identifier:
eissn:
- '20411723'
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Cell kinetics of auxin transport and activity in Arabidopsis root growth and
skewing
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 12
year: '2021'
...
---
_id: '9255'
abstract:
- lang: eng
text: Our ability to trust that a random number is truly random is essential for
fields as diverse as cryptography and fundamental tests of quantum mechanics.
Existing solutions both come with drawbacks—device-independent quantum random
number generators (QRNGs) are highly impractical and standard semi-device-independent
QRNGs are limited to a specific physical implementation and level of trust. Here
we propose a framework for semi-device-independent randomness certification, using
a source of trusted vacuum in the form of a signal shutter. It employs a flexible
set of assumptions and levels of trust, allowing it to be applied in a wide range
of physical scenarios involving both quantum and classical entropy sources. We
experimentally demonstrate our protocol with a photonic setup and generate secure
random bits under three different assumptions with varying degrees of security
and resulting data rates.
acknowledgement: We would like to thank Robert Fickler for discussions about the experimental
realization and Marek Sýs for running the NIST randomness test on the data we acquired
in the experiment. We would like to thank Ugo Zanforlin, Gerald Buller, Daniel White,
and Cristian Bonato for their help with the experiment. M. Pivoluska, M. Plesch,
and M.M. acknowledge Czech-Austrian project MultiQUEST (I3053-N27 and GF17-33780L).
M. Pivoluska and M. Plesch additionally acknowledge the support of VEGA project
2/0136/19. M.F. acknowledges support from the Polish NCN grant Sonata UMO-2014/14/E/ST2/00020,
the European Research Council (ERC) under the European Union’s Horizon 2020 research
and innovation program ERC AdG CERQUTE (grant agreement No 834266), the State Research
Agency (AEI) TRANQI (PID2019-106888GB-I00/10.13039/501100011033), the Government
of Spain (FIS2020-TRANQI; Severo Ochoa CEX2019-000910-S), Fundació Cellex, Fundació
Mir-Puig, and Generalitat de Catalunya (CERCA, AGAUR). M.M., W.M., N.H.V., and C.F.
acknowledge support from the QuantERA ERA-NET Co-fund (FWF Project I3773-N36) and
the UK Engineering and Physical Sciences Research Council (EPSRC) (EP/P024114/1).
article_number: '50'
article_processing_charge: No
article_type: original
author:
- first_name: Matej
full_name: Pivoluska, Matej
last_name: Pivoluska
- first_name: Martin
full_name: Plesch, Martin
last_name: Plesch
- first_name: Máté
full_name: Farkas, Máté
last_name: Farkas
- first_name: Natalia
full_name: Ruzickova, Natalia
id: D2761128-D73D-11E9-A1BF-BA0DE6697425
last_name: Ruzickova
- first_name: Clara
full_name: Flegel, Clara
last_name: Flegel
- first_name: Natalia Herrera
full_name: Valencia, Natalia Herrera
last_name: Valencia
- first_name: Will
full_name: Mccutcheon, Will
last_name: Mccutcheon
- first_name: Mehul
full_name: Malik, Mehul
last_name: Malik
- first_name: Edgar A.
full_name: Aguilar, Edgar A.
last_name: Aguilar
citation:
ama: Pivoluska M, Plesch M, Farkas M, et al. Semi-device-independent random number
generation with flexible assumptions. npj Quantum Information. 2021;7.
doi:10.1038/s41534-021-00387-1
apa: Pivoluska, M., Plesch, M., Farkas, M., Ruzickova, N., Flegel, C., Valencia,
N. H., … Aguilar, E. A. (2021). Semi-device-independent random number generation
with flexible assumptions. Npj Quantum Information. Springer Nature. https://doi.org/10.1038/s41534-021-00387-1
chicago: Pivoluska, Matej, Martin Plesch, Máté Farkas, Natalia Ruzickova, Clara
Flegel, Natalia Herrera Valencia, Will Mccutcheon, Mehul Malik, and Edgar A. Aguilar.
“Semi-Device-Independent Random Number Generation with Flexible Assumptions.”
Npj Quantum Information. Springer Nature, 2021. https://doi.org/10.1038/s41534-021-00387-1.
ieee: M. Pivoluska et al., “Semi-device-independent random number generation
with flexible assumptions,” npj Quantum Information, vol. 7. Springer Nature,
2021.
ista: Pivoluska M, Plesch M, Farkas M, Ruzickova N, Flegel C, Valencia NH, Mccutcheon
W, Malik M, Aguilar EA. 2021. Semi-device-independent random number generation
with flexible assumptions. npj Quantum Information. 7, 50.
mla: Pivoluska, Matej, et al. “Semi-Device-Independent Random Number Generation
with Flexible Assumptions.” Npj Quantum Information, vol. 7, 50, Springer
Nature, 2021, doi:10.1038/s41534-021-00387-1.
short: M. Pivoluska, M. Plesch, M. Farkas, N. Ruzickova, C. Flegel, N.H. Valencia,
W. Mccutcheon, M. Malik, E.A. Aguilar, Npj Quantum Information 7 (2021).
date_created: 2021-03-21T23:01:19Z
date_published: 2021-03-15T00:00:00Z
date_updated: 2023-08-07T14:17:26Z
day: '15'
ddc:
- '530'
department:
- _id: FyKo
doi: 10.1038/s41534-021-00387-1
external_id:
isi:
- '000629173100001'
file:
- access_level: open_access
checksum: 26d3f2a2c8c8fa8c1002028326b45f64
content_type: application/pdf
creator: dernst
date_created: 2021-03-22T11:09:34Z
date_updated: 2021-03-22T11:09:34Z
file_id: '9274'
file_name: 2021_NPJQuantumInformation_Pivoluska.pdf
file_size: 1360271
relation: main_file
success: 1
file_date_updated: 2021-03-22T11:09:34Z
has_accepted_license: '1'
intvolume: ' 7'
isi: 1
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
publication: npj Quantum Information
publication_identifier:
eissn:
- 2056-6387
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Semi-device-independent random number generation with flexible assumptions
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 7
year: '2021'
...
---
_id: '9256'
abstract:
- lang: eng
text: We consider the ferromagnetic quantum Heisenberg model in one dimension, for
any spin S≥1/2. We give upper and lower bounds on the free energy, proving that
at low temperature it is asymptotically equal to the one of an ideal Bose gas
of magnons, as predicted by the spin-wave approximation. The trial state used
in the upper bound yields an analogous estimate also in the case of two spatial
dimensions, which is believed to be sharp at low temperature.
acknowledgement: "The work of MN was supported by the National Science Centre (NCN)
Project Nr. 2016/21/D/ST1/02430. The work of RS was supported by the European Research
Council (ERC) under the European Union’s Horizon 2020 research and innovation programme
(Grant Agreement No. 694227).\r\nOpen access funding provided by Institute of Science
and Technology (IST Austria)."
article_number: '31'
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Marcin M
full_name: Napiórkowski, Marcin M
id: 4197AD04-F248-11E8-B48F-1D18A9856A87
last_name: Napiórkowski
- first_name: Robert
full_name: Seiringer, Robert
id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
last_name: Seiringer
orcid: 0000-0002-6781-0521
citation:
ama: Napiórkowski MM, Seiringer R. Free energy asymptotics of the quantum Heisenberg
spin chain. Letters in Mathematical Physics. 2021;111(2). doi:10.1007/s11005-021-01375-4
apa: Napiórkowski, M. M., & Seiringer, R. (2021). Free energy asymptotics of
the quantum Heisenberg spin chain. Letters in Mathematical Physics. Springer
Nature. https://doi.org/10.1007/s11005-021-01375-4
chicago: Napiórkowski, Marcin M, and Robert Seiringer. “Free Energy Asymptotics
of the Quantum Heisenberg Spin Chain.” Letters in Mathematical Physics.
Springer Nature, 2021. https://doi.org/10.1007/s11005-021-01375-4.
ieee: M. M. Napiórkowski and R. Seiringer, “Free energy asymptotics of the quantum
Heisenberg spin chain,” Letters in Mathematical Physics, vol. 111, no.
2. Springer Nature, 2021.
ista: Napiórkowski MM, Seiringer R. 2021. Free energy asymptotics of the quantum
Heisenberg spin chain. Letters in Mathematical Physics. 111(2), 31.
mla: Napiórkowski, Marcin M., and Robert Seiringer. “Free Energy Asymptotics of
the Quantum Heisenberg Spin Chain.” Letters in Mathematical Physics, vol.
111, no. 2, 31, Springer Nature, 2021, doi:10.1007/s11005-021-01375-4.
short: M.M. Napiórkowski, R. Seiringer, Letters in Mathematical Physics 111 (2021).
date_created: 2021-03-21T23:01:19Z
date_published: 2021-03-09T00:00:00Z
date_updated: 2023-08-07T14:17:00Z
day: '09'
ddc:
- '510'
department:
- _id: RoSe
doi: 10.1007/s11005-021-01375-4
external_id:
isi:
- '000626837400001'
file:
- access_level: open_access
checksum: 687fef1525789c0950de90468dd81604
content_type: application/pdf
creator: dernst
date_created: 2021-03-22T11:01:09Z
date_updated: 2021-03-22T11:01:09Z
file_id: '9273'
file_name: 2021_LettersMathPhysics_Napiorkowski.pdf
file_size: 397962
relation: main_file
success: 1
file_date_updated: 2021-03-22T11:01:09Z
has_accepted_license: '1'
intvolume: ' 111'
isi: 1
issue: '2'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
publication: Letters in Mathematical Physics
publication_identifier:
eissn:
- '15730530'
issn:
- '03779017'
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Free energy asymptotics of the quantum Heisenberg spin chain
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 111
year: '2021'
...
---
_id: '9257'
abstract:
- lang: eng
text: 'The inverse problem of designing component interactions to target emergent
structure is fundamental to numerous applications in biotechnology, materials
science, and statistical physics. Equally important is the inverse problem of
designing emergent kinetics, but this has received considerably less attention.
Using recent advances in automatic differentiation, we show how kinetic pathways
can be precisely designed by directly differentiating through statistical physics
models, namely free energy calculations and molecular dynamics simulations. We
consider two systems that are crucial to our understanding of structural self-assembly:
bulk crystallization and small nanoclusters. In each case, we are able to assemble
precise dynamical features. Using gradient information, we manipulate interactions
among constituent particles to tune the rate at which these systems yield specific
structures of interest. Moreover, we use this approach to learn nontrivial features
about the high-dimensional design space, allowing us to accurately predict when
multiple kinetic features can be simultaneously and independently controlled.
These results provide a concrete and generalizable foundation for studying nonstructural
self-assembly, including kinetic properties as well as other complex emergent
properties, in a vast array of systems.'
acknowledgement: We thank Agnese Curatolo, Megan Engel, Ofer Kimchi, Seong Ho Pahng,
and Roy Frostig for helpful discussions. This material is based on work supported
by NSF Graduate Research Fellowship Grant DGE1745303. This research was funded by
NSF Grant DMS-1715477, Materials Research Science and Engineering Centers Grant
DMR-1420570, and Office of Naval Research Grant N00014-17-1-3029. M.P.B. is an investigator
of the Simons Foundation.
article_number: e2024083118
article_processing_charge: No
article_type: original
author:
- first_name: Carl Peter
full_name: Goodrich, Carl Peter
id: EB352CD2-F68A-11E9-89C5-A432E6697425
last_name: Goodrich
orcid: 0000-0002-1307-5074
- first_name: Ella M.
full_name: King, Ella M.
last_name: King
- first_name: Samuel S.
full_name: Schoenholz, Samuel S.
last_name: Schoenholz
- first_name: Ekin D.
full_name: Cubuk, Ekin D.
last_name: Cubuk
- first_name: Michael P.
full_name: Brenner, Michael P.
last_name: Brenner
citation:
ama: Goodrich CP, King EM, Schoenholz SS, Cubuk ED, Brenner MP. Designing self-assembling
kinetics with differentiable statistical physics models. Proceedings of the
National Academy of Sciences. 2021;118(10). doi:10.1073/pnas.2024083118
apa: Goodrich, C. P., King, E. M., Schoenholz, S. S., Cubuk, E. D., & Brenner,
M. P. (2021). Designing self-assembling kinetics with differentiable statistical
physics models. Proceedings of the National Academy of Sciences. National
Academy of Sciences. https://doi.org/10.1073/pnas.2024083118
chicago: Goodrich, Carl Peter, Ella M. King, Samuel S. Schoenholz, Ekin D. Cubuk,
and Michael P. Brenner. “Designing Self-Assembling Kinetics with Differentiable
Statistical Physics Models.” Proceedings of the National Academy of Sciences.
National Academy of Sciences, 2021. https://doi.org/10.1073/pnas.2024083118.
ieee: C. P. Goodrich, E. M. King, S. S. Schoenholz, E. D. Cubuk, and M. P. Brenner,
“Designing self-assembling kinetics with differentiable statistical physics models,”
Proceedings of the National Academy of Sciences, vol. 118, no. 10. National
Academy of Sciences, 2021.
ista: Goodrich CP, King EM, Schoenholz SS, Cubuk ED, Brenner MP. 2021. Designing
self-assembling kinetics with differentiable statistical physics models. Proceedings
of the National Academy of Sciences. 118(10), e2024083118.
mla: Goodrich, Carl Peter, et al. “Designing Self-Assembling Kinetics with Differentiable
Statistical Physics Models.” Proceedings of the National Academy of Sciences,
vol. 118, no. 10, e2024083118, National Academy of Sciences, 2021, doi:10.1073/pnas.2024083118.
short: C.P. Goodrich, E.M. King, S.S. Schoenholz, E.D. Cubuk, M.P. Brenner, Proceedings
of the National Academy of Sciences 118 (2021).
date_created: 2021-03-21T23:01:20Z
date_published: 2021-03-09T00:00:00Z
date_updated: 2023-08-07T14:19:34Z
day: '09'
ddc:
- '530'
department:
- _id: CaGo
doi: 10.1073/pnas.2024083118
external_id:
isi:
- '000627429100097'
pmid:
- '33653960'
file:
- access_level: open_access
checksum: 5be8da2b1c0757feb1057f1a515cf9e0
content_type: application/pdf
creator: dernst
date_created: 2021-03-22T12:23:54Z
date_updated: 2021-03-22T12:23:54Z
file_id: '9278'
file_name: 2021_PNAS_Goodrich.pdf
file_size: 1047954
relation: main_file
success: 1
file_date_updated: 2021-03-22T12:23:54Z
has_accepted_license: '1'
intvolume: ' 118'
isi: 1
issue: '10'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-nd/4.0/
month: '03'
oa: 1
oa_version: Published Version
pmid: 1
publication: Proceedings of the National Academy of Sciences
publication_identifier:
eissn:
- 1091-6490
issn:
- 0027-8424
publication_status: published
publisher: National Academy of Sciences
quality_controlled: '1'
scopus_import: '1'
status: public
title: Designing self-assembling kinetics with differentiable statistical physics
models
tmp:
image: /images/cc_by_nc_nd.png
legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
(CC BY-NC-ND 4.0)
short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 118
year: '2021'
...
---
_id: '9258'
acknowledgement: 'We thank S. van der Walt and K. Marchuk for discussion during development.
This project was funded by Packard Fellowship and Chan Zuckerberg Biohub Investigator
Awards to L.W.; STROBE: A NSF Science and Technology Center; an NSF Graduate Research
Fellowship awarded to H.P.; a Berkeley Institute for Data Science/UCSF Bakar Computational
Health Sciences Institute Fellowship awarded to H.P. with support from the Koret
Foundation, the Gordon and Betty Moore Foundation, and the Alfred P. Sloan Foundation
to the University of California, Berkeley. K.W.E., B.L. and M.T. were funded by
the Chan Zuckerberg Initiative and NIH grant P41GM135019.'
article_processing_charge: No
article_type: letter_note
author:
- first_name: Henry
full_name: Pinkard, Henry
last_name: Pinkard
- first_name: Nico
full_name: Stuurman, Nico
last_name: Stuurman
- first_name: Ivan E.
full_name: Ivanov, Ivan E.
last_name: Ivanov
- first_name: Nicholas M.
full_name: Anthony, Nicholas M.
last_name: Anthony
- first_name: Wei
full_name: Ouyang, Wei
last_name: Ouyang
- first_name: Bin
full_name: Li, Bin
last_name: Li
- first_name: Bin
full_name: Yang, Bin
last_name: Yang
- first_name: Mark A.
full_name: Tsuchida, Mark A.
last_name: Tsuchida
- first_name: Bryant
full_name: Chhun, Bryant
last_name: Chhun
- first_name: Grace
full_name: Zhang, Grace
last_name: Zhang
- first_name: Ryan
full_name: Mei, Ryan
last_name: Mei
- first_name: Michael
full_name: Anderson, Michael
last_name: Anderson
- first_name: Douglas P.
full_name: Shepherd, Douglas P.
last_name: Shepherd
- first_name: Ian
full_name: Hunt-Isaak, Ian
last_name: Hunt-Isaak
- first_name: Raymond L.
full_name: Dunn, Raymond L.
last_name: Dunn
- first_name: Wiebke
full_name: Jahr, Wiebke
id: 425C1CE8-F248-11E8-B48F-1D18A9856A87
last_name: Jahr
- first_name: Saul
full_name: Kato, Saul
last_name: Kato
- first_name: Loïc A.
full_name: Royer, Loïc A.
last_name: Royer
- first_name: Jay R.
full_name: Thiagarajah, Jay R.
last_name: Thiagarajah
- first_name: Kevin W.
full_name: Eliceiri, Kevin W.
last_name: Eliceiri
- first_name: Emma
full_name: Lundberg, Emma
last_name: Lundberg
- first_name: Shalin B.
full_name: Mehta, Shalin B.
last_name: Mehta
- first_name: Laura
full_name: Waller, Laura
last_name: Waller
citation:
ama: 'Pinkard H, Stuurman N, Ivanov IE, et al. Pycro-Manager: Open-source software
for customized and reproducible microscope control. Nature Methods. 2021;18(3):226-228.
doi:10.1038/s41592-021-01087-6'
apa: 'Pinkard, H., Stuurman, N., Ivanov, I. E., Anthony, N. M., Ouyang, W., Li,
B., … Waller, L. (2021). Pycro-Manager: Open-source software for customized and
reproducible microscope control. Nature Methods. Springer Nature. https://doi.org/10.1038/s41592-021-01087-6'
chicago: 'Pinkard, Henry, Nico Stuurman, Ivan E. Ivanov, Nicholas M. Anthony, Wei
Ouyang, Bin Li, Bin Yang, et al. “Pycro-Manager: Open-Source Software for Customized
and Reproducible Microscope Control.” Nature Methods. Springer Nature,
2021. https://doi.org/10.1038/s41592-021-01087-6.'
ieee: 'H. Pinkard et al., “Pycro-Manager: Open-source software for customized
and reproducible microscope control,” Nature Methods, vol. 18, no. 3. Springer
Nature, pp. 226–228, 2021.'
ista: 'Pinkard H, Stuurman N, Ivanov IE, Anthony NM, Ouyang W, Li B, Yang B, Tsuchida
MA, Chhun B, Zhang G, Mei R, Anderson M, Shepherd DP, Hunt-Isaak I, Dunn RL, Jahr
W, Kato S, Royer LA, Thiagarajah JR, Eliceiri KW, Lundberg E, Mehta SB, Waller
L. 2021. Pycro-Manager: Open-source software for customized and reproducible microscope
control. Nature Methods. 18(3), 226–228.'
mla: 'Pinkard, Henry, et al. “Pycro-Manager: Open-Source Software for Customized
and Reproducible Microscope Control.” Nature Methods, vol. 18, no. 3, Springer
Nature, 2021, pp. 226–28, doi:10.1038/s41592-021-01087-6.'
short: H. Pinkard, N. Stuurman, I.E. Ivanov, N.M. Anthony, W. Ouyang, B. Li, B.
Yang, M.A. Tsuchida, B. Chhun, G. Zhang, R. Mei, M. Anderson, D.P. Shepherd, I.
Hunt-Isaak, R.L. Dunn, W. Jahr, S. Kato, L.A. Royer, J.R. Thiagarajah, K.W. Eliceiri,
E. Lundberg, S.B. Mehta, L. Waller, Nature Methods 18 (2021) 226–228.
date_created: 2021-03-21T23:01:20Z
date_published: 2021-03-01T00:00:00Z
date_updated: 2023-08-07T14:19:08Z
day: '01'
department:
- _id: JoDa
doi: 10.1038/s41592-021-01087-6
external_id:
isi:
- '000625600600007'
pmid:
- '33674797'
intvolume: ' 18'
isi: 1
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1038/s41592-021-01087-6
month: '03'
oa: 1
oa_version: Published Version
page: 226-228
pmid: 1
publication: Nature Methods
publication_identifier:
eissn:
- 1548-7105
issn:
- 1548-7091
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Pycro-Manager: Open-source software for customized and reproducible microscope
control'
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 18
year: '2021'
...
---
_id: '9259'
abstract:
- lang: eng
text: Gradients of chemokines and growth factors guide migrating cells and morphogenetic
processes. Migration of antigen-presenting dendritic cells from the interstitium
into the lymphatic system is dependent on chemokine CCL21, which is secreted by
endothelial cells of the lymphatic capillary, binds heparan sulfates and forms
gradients decaying into the interstitium. Despite the importance of CCL21 gradients,
and chemokine gradients in general, the mechanisms of gradient formation are unclear.
Studies on fibroblast growth factors have shown that limited diffusion is crucial
for gradient formation. Here, we used the mouse dermis as a model tissue to address
the necessity of CCL21 anchoring to lymphatic capillary heparan sulfates in the
formation of interstitial CCL21 gradients. Surprisingly, the absence of lymphatic
endothelial heparan sulfates resulted only in a modest decrease of CCL21 levels
at the lymphatic capillaries and did neither affect interstitial CCL21 gradient
shape nor dendritic cell migration toward lymphatic capillaries. Thus, heparan
sulfates at the level of the lymphatic endothelium are dispensable for the formation
of a functional CCL21 gradient.
acknowledgement: "This work was supported by Sigrid Juselius fellowship (KV), University
of Helsinki 3-year research grant (KV), Academy of Finland Research fellow funding
(315710, to KV), the European Research Council (ERC CoG 724373 to MS), and by the
Austrian Science foundation (FWF) (Y564-B12 START award to MS).\r\nTaija Mäkinen
is acknowledged for providing Prox1CreERT2 transgenic mice and Yu Yamaguchi for
providing the conditional Ext1 mouse strain."
article_number: '630002'
article_processing_charge: No
article_type: original
author:
- first_name: Kari
full_name: Vaahtomeri, Kari
id: 368EE576-F248-11E8-B48F-1D18A9856A87
last_name: Vaahtomeri
orcid: 0000-0001-7829-3518
- first_name: Christine
full_name: Moussion, Christine
id: 3356F664-F248-11E8-B48F-1D18A9856A87
last_name: Moussion
- first_name: Robert
full_name: Hauschild, Robert
id: 4E01D6B4-F248-11E8-B48F-1D18A9856A87
last_name: Hauschild
orcid: 0000-0001-9843-3522
- first_name: Michael K
full_name: Sixt, Michael K
id: 41E9FBEA-F248-11E8-B48F-1D18A9856A87
last_name: Sixt
orcid: 0000-0002-6620-9179
citation:
ama: Vaahtomeri K, Moussion C, Hauschild R, Sixt MK. Shape and function of interstitial
chemokine CCL21 gradients are independent of heparan sulfates produced by lymphatic
endothelium. Frontiers in Immunology. 2021;12. doi:10.3389/fimmu.2021.630002
apa: Vaahtomeri, K., Moussion, C., Hauschild, R., & Sixt, M. K. (2021). Shape
and function of interstitial chemokine CCL21 gradients are independent of heparan
sulfates produced by lymphatic endothelium. Frontiers in Immunology. Frontiers.
https://doi.org/10.3389/fimmu.2021.630002
chicago: Vaahtomeri, Kari, Christine Moussion, Robert Hauschild, and Michael K Sixt.
“Shape and Function of Interstitial Chemokine CCL21 Gradients Are Independent
of Heparan Sulfates Produced by Lymphatic Endothelium.” Frontiers in Immunology.
Frontiers, 2021. https://doi.org/10.3389/fimmu.2021.630002.
ieee: K. Vaahtomeri, C. Moussion, R. Hauschild, and M. K. Sixt, “Shape and function
of interstitial chemokine CCL21 gradients are independent of heparan sulfates
produced by lymphatic endothelium,” Frontiers in Immunology, vol. 12. Frontiers,
2021.
ista: Vaahtomeri K, Moussion C, Hauschild R, Sixt MK. 2021. Shape and function of
interstitial chemokine CCL21 gradients are independent of heparan sulfates produced
by lymphatic endothelium. Frontiers in Immunology. 12, 630002.
mla: Vaahtomeri, Kari, et al. “Shape and Function of Interstitial Chemokine CCL21
Gradients Are Independent of Heparan Sulfates Produced by Lymphatic Endothelium.”
Frontiers in Immunology, vol. 12, 630002, Frontiers, 2021, doi:10.3389/fimmu.2021.630002.
short: K. Vaahtomeri, C. Moussion, R. Hauschild, M.K. Sixt, Frontiers in Immunology
12 (2021).
date_created: 2021-03-21T23:01:20Z
date_published: 2021-02-25T00:00:00Z
date_updated: 2023-08-07T14:18:26Z
day: '25'
ddc:
- '570'
department:
- _id: MiSi
- _id: Bio
doi: 10.3389/fimmu.2021.630002
ec_funded: 1
external_id:
isi:
- '000627134400001'
pmid:
- '33717158'
file:
- access_level: open_access
checksum: 663f5a48375e42afa4bfef58d42ec186
content_type: application/pdf
creator: dernst
date_created: 2021-03-22T12:08:26Z
date_updated: 2021-03-22T12:08:26Z
file_id: '9277'
file_name: 2021_FrontiersImmumo_Vaahtomeri.pdf
file_size: 3740146
relation: main_file
success: 1
file_date_updated: 2021-03-22T12:08:26Z
has_accepted_license: '1'
intvolume: ' 12'
isi: 1
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 25FE9508-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '724373'
name: Cellular navigation along spatial gradients
- _id: 25A8E5EA-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: Y 564-B12
name: Cytoskeletal force generation and force transduction of migrating leukocytes
publication: Frontiers in Immunology
publication_identifier:
eissn:
- 1664-3224
publication_status: published
publisher: Frontiers
quality_controlled: '1'
scopus_import: '1'
status: public
title: Shape and function of interstitial chemokine CCL21 gradients are independent
of heparan sulfates produced by lymphatic endothelium
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 12
year: '2021'
...
---
_id: '9260'
abstract:
- lang: eng
text: We study the density of rational points on a higher-dimensional orbifold (Pn−1,Δ)
when Δ is a Q-divisor involving hyperplanes. This allows us to address a question
of Tanimoto about whether the set of rational points on such an orbifold constitutes
a thin set. Our approach relies on the Hardy–Littlewood circle method to first
study an asymptotic version of Waring’s problem for mixed powers. In doing so
we make crucial use of the recent resolution of the main conjecture in Vinogradov’s
mean value theorem, due to Bourgain–Demeter–Guth and Wooley.
acknowledgement: While working on this paper the authors were both supported by EPSRC
grant EP/P026710/1, and the second author received additional support from the NWO
Veni Grant 016.Veni.192.047. Thanks are due to Marta Pieropan, Arne Smeets and Sho
Tanimoto for useful conversations related to this topic, and to the anonymous referee
for numerous helpful suggestions.
article_processing_charge: No
article_type: original
author:
- first_name: Timothy D
full_name: Browning, Timothy D
id: 35827D50-F248-11E8-B48F-1D18A9856A87
last_name: Browning
orcid: 0000-0002-8314-0177
- first_name: Shuntaro
full_name: Yamagishi, Shuntaro
last_name: Yamagishi
citation:
ama: Browning TD, Yamagishi S. Arithmetic of higher-dimensional orbifolds and a
mixed Waring problem. Mathematische Zeitschrift. 2021;299:1071–1101. doi:10.1007/s00209-021-02695-w
apa: Browning, T. D., & Yamagishi, S. (2021). Arithmetic of higher-dimensional
orbifolds and a mixed Waring problem. Mathematische Zeitschrift. Springer
Nature. https://doi.org/10.1007/s00209-021-02695-w
chicago: Browning, Timothy D, and Shuntaro Yamagishi. “Arithmetic of Higher-Dimensional
Orbifolds and a Mixed Waring Problem.” Mathematische Zeitschrift. Springer
Nature, 2021. https://doi.org/10.1007/s00209-021-02695-w.
ieee: T. D. Browning and S. Yamagishi, “Arithmetic of higher-dimensional orbifolds
and a mixed Waring problem,” Mathematische Zeitschrift, vol. 299. Springer
Nature, pp. 1071–1101, 2021.
ista: Browning TD, Yamagishi S. 2021. Arithmetic of higher-dimensional orbifolds
and a mixed Waring problem. Mathematische Zeitschrift. 299, 1071–1101.
mla: Browning, Timothy D., and Shuntaro Yamagishi. “Arithmetic of Higher-Dimensional
Orbifolds and a Mixed Waring Problem.” Mathematische Zeitschrift, vol.
299, Springer Nature, 2021, pp. 1071–1101, doi:10.1007/s00209-021-02695-w.
short: T.D. Browning, S. Yamagishi, Mathematische Zeitschrift 299 (2021) 1071–1101.
date_created: 2021-03-21T23:01:21Z
date_published: 2021-03-05T00:00:00Z
date_updated: 2023-08-07T14:20:00Z
day: '05'
ddc:
- '510'
department:
- _id: TiBr
doi: 10.1007/s00209-021-02695-w
external_id:
isi:
- '000625573800002'
file:
- access_level: open_access
checksum: 8ed9f49568806894744096dbbca0ad7b
content_type: application/pdf
creator: dernst
date_created: 2021-03-22T12:41:26Z
date_updated: 2021-03-22T12:41:26Z
file_id: '9279'
file_name: 2021_MathZeitschrift_Browning.pdf
file_size: 492685
relation: main_file
success: 1
file_date_updated: 2021-03-22T12:41:26Z
has_accepted_license: '1'
intvolume: ' 299'
isi: 1
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
page: 1071–1101
project:
- _id: 26A8D266-B435-11E9-9278-68D0E5697425
grant_number: EP-P026710-2
name: Between rational and integral points
publication: Mathematische Zeitschrift
publication_identifier:
eissn:
- 1432-1823
issn:
- 0025-5874
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Arithmetic of higher-dimensional orbifolds and a mixed Waring problem
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 299
year: '2021'
...
---
_id: '9262'
abstract:
- lang: eng
text: Sequence-specific oligomers with predictable folding patterns, i.e., foldamers,
provide new opportunities to mimic α-helical peptides and design inhibitors of
protein-protein interactions. One major hurdle of this strategy is to retain the
correct orientation of key side chains involved in protein surface recognition.
Here, we show that the structural plasticity of a foldamer backbone may notably
contribute to the required spatial adjustment for optimal interaction with the
protein surface. By using oligoureas as α helix mimics, we designed a foldamer/peptide
hybrid inhibitor of histone chaperone ASF1, a key regulator of chromatin dynamics.
The crystal structure of its complex with ASF1 reveals a notable plasticity of
the urea backbone, which adapts to the ASF1 surface to maintain the same binding
interface. One additional benefit of generating ASF1 ligands with nonpeptide oligourea
segments is the resistance to proteolysis in human plasma, which was highly improved
compared to the cognate α-helical peptide.
acknowledgement: 'We thank the Synchrotron SOLEIL, the European Synchrotron Radiation
Facility (ESRF), and the French Infrastructure for Integrated Structural Biology
(FRISBI) ANR-10-INBS-05. We are particularly grateful to A. Clavier and A. Campalans
for help in setting up and performing the cell penetration assays. Funding: Research
was funded by the French Centre National de Recherche Scientifique (CNRS), the Commissariat
à l’Energie Atomique (CEA), University of Bordeaux, University Paris-Saclay, and
the Synchrotron Soleil. The project was supported by the ANR 2007 BREAKABOUND (JC-07-216078),
2011 BIPBIP (ANR-10-BINF-0003), 2012 CHAPINHIB (ANR-12-BSV5-0022-01), 2015 CHIPSET
(ANR-15-CE11-008-01), 2015 HIMPP2I (ANR-15-CE07-0010), and the program labeled by
the ARC foundation 2016 PGA1*20160203953). M.B. was supported by Canceropole (Paris,
France) and a grant for young researchers from La Ligue contre le Cancer. J.M. was
supported by La Ligue contre le Cancer.'
article_number: eabd9153
article_processing_charge: No
article_type: original
author:
- first_name: Johanne
full_name: Mbianda, Johanne
last_name: Mbianda
- first_name: May M
full_name: Bakail, May M
id: FB3C3F8E-522F-11EA-B186-22963DDC885E
last_name: Bakail
orcid: 0000-0002-9592-1587
- first_name: Christophe
full_name: André, Christophe
last_name: André
- first_name: Gwenaëlle
full_name: Moal, Gwenaëlle
last_name: Moal
- first_name: Marie E.
full_name: Perrin, Marie E.
last_name: Perrin
- first_name: Guillaume
full_name: Pinna, Guillaume
last_name: Pinna
- first_name: Raphaël
full_name: Guerois, Raphaël
last_name: Guerois
- first_name: Francois
full_name: Becher, Francois
last_name: Becher
- first_name: Pierre
full_name: Legrand, Pierre
last_name: Legrand
- first_name: Seydou
full_name: Traoré, Seydou
last_name: Traoré
- first_name: Céline
full_name: Douat, Céline
last_name: Douat
- first_name: Gilles
full_name: Guichard, Gilles
last_name: Guichard
- first_name: Françoise
full_name: Ochsenbein, Françoise
last_name: Ochsenbein
citation:
ama: Mbianda J, Bakail MM, André C, et al. Optimal anchoring of a foldamer inhibitor
of ASF1 histone chaperone through backbone plasticity. Science Advances.
2021;7(12). doi:10.1126/sciadv.abd9153
apa: Mbianda, J., Bakail, M. M., André, C., Moal, G., Perrin, M. E., Pinna, G.,
… Ochsenbein, F. (2021). Optimal anchoring of a foldamer inhibitor of ASF1 histone
chaperone through backbone plasticity. Science Advances. American Association
for the Advancement of Science. https://doi.org/10.1126/sciadv.abd9153
chicago: Mbianda, Johanne, May M Bakail, Christophe André, Gwenaëlle Moal, Marie
E. Perrin, Guillaume Pinna, Raphaël Guerois, et al. “Optimal Anchoring of a Foldamer
Inhibitor of ASF1 Histone Chaperone through Backbone Plasticity.” Science Advances.
American Association for the Advancement of Science, 2021. https://doi.org/10.1126/sciadv.abd9153.
ieee: J. Mbianda et al., “Optimal anchoring of a foldamer inhibitor of ASF1
histone chaperone through backbone plasticity,” Science Advances, vol.
7, no. 12. American Association for the Advancement of Science, 2021.
ista: Mbianda J, Bakail MM, André C, Moal G, Perrin ME, Pinna G, Guerois R, Becher
F, Legrand P, Traoré S, Douat C, Guichard G, Ochsenbein F. 2021. Optimal anchoring
of a foldamer inhibitor of ASF1 histone chaperone through backbone plasticity.
Science Advances. 7(12), eabd9153.
mla: Mbianda, Johanne, et al. “Optimal Anchoring of a Foldamer Inhibitor of ASF1
Histone Chaperone through Backbone Plasticity.” Science Advances, vol.
7, no. 12, eabd9153, American Association for the Advancement of Science, 2021,
doi:10.1126/sciadv.abd9153.
short: J. Mbianda, M.M. Bakail, C. André, G. Moal, M.E. Perrin, G. Pinna, R. Guerois,
F. Becher, P. Legrand, S. Traoré, C. Douat, G. Guichard, F. Ochsenbein, Science
Advances 7 (2021).
date_created: 2021-03-22T07:14:03Z
date_published: 2021-03-19T00:00:00Z
date_updated: 2023-08-07T14:20:26Z
day: '19'
ddc:
- '570'
department:
- _id: CampIT
doi: 10.1126/sciadv.abd9153
external_id:
isi:
- '000633443000011'
pmid:
- '33741589'
file:
- access_level: open_access
checksum: 737624cd0e630ffa7c52797a690500e3
content_type: application/pdf
creator: dernst
date_created: 2021-03-22T12:49:00Z
date_updated: 2021-03-22T12:49:00Z
file_id: '9280'
file_name: 2021_ScienceAdv_Mbianda.pdf
file_size: 837156
relation: main_file
success: 1
file_date_updated: 2021-03-22T12:49:00Z
has_accepted_license: '1'
intvolume: ' 7'
isi: 1
issue: '12'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc/4.0/
month: '03'
oa: 1
oa_version: Published Version
pmid: 1
publication: Science Advances
publication_identifier:
issn:
- 2375-2548
publication_status: published
publisher: American Association for the Advancement of Science
quality_controlled: '1'
status: public
title: Optimal anchoring of a foldamer inhibitor of ASF1 histone chaperone through
backbone plasticity
tmp:
image: /images/cc_by_nc.png
legal_code_url: https://creativecommons.org/licenses/by-nc/4.0/legalcode
name: Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
short: CC BY-NC (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 7
year: '2021'
...
---
_id: '9281'
abstract:
- lang: eng
text: We comment on two formal proofs of Fermat's sum of two squares theorem, written
using the Mathematical Components libraries of the Coq proof assistant. The first
one follows Zagier's celebrated one-sentence proof; the second follows David Christopher's
recent new proof relying on partition-theoretic arguments. Both formal proofs
rely on a general property of involutions of finite sets, of independent interest.
The proof technique consists for the most part of automating recurrent tasks (such
as case distinctions and computations on natural numbers) via ad hoc tactics.
article_number: '2103.11389'
article_processing_charge: No
arxiv: 1
author:
- first_name: Guillaume
full_name: Dubach, Guillaume
id: D5C6A458-10C4-11EA-ABF4-A4B43DDC885E
last_name: Dubach
orcid: 0000-0001-6892-8137
- first_name: Fabian
full_name: Mühlböck, Fabian
id: 6395C5F6-89DF-11E9-9C97-6BDFE5697425
last_name: Mühlböck
orcid: 0000-0003-1548-0177
citation:
ama: Dubach G, Mühlböck F. Formal verification of Zagier’s one-sentence proof. arXiv.
doi:10.48550/arXiv.2103.11389
apa: Dubach, G., & Mühlböck, F. (n.d.). Formal verification of Zagier’s one-sentence
proof. arXiv. https://doi.org/10.48550/arXiv.2103.11389
chicago: Dubach, Guillaume, and Fabian Mühlböck. “Formal Verification of Zagier’s
One-Sentence Proof.” ArXiv, n.d. https://doi.org/10.48550/arXiv.2103.11389.
ieee: G. Dubach and F. Mühlböck, “Formal verification of Zagier’s one-sentence proof,”
arXiv. .
ista: Dubach G, Mühlböck F. Formal verification of Zagier’s one-sentence proof.
arXiv, 2103.11389.
mla: Dubach, Guillaume, and Fabian Mühlböck. “Formal Verification of Zagier’s One-Sentence
Proof.” ArXiv, 2103.11389, doi:10.48550/arXiv.2103.11389.
short: G. Dubach, F. Mühlböck, ArXiv (n.d.).
date_created: 2021-03-23T05:38:48Z
date_published: 2021-03-21T00:00:00Z
date_updated: 2023-05-03T10:26:45Z
day: '21'
department:
- _id: LaEr
- _id: ToHe
doi: 10.48550/arXiv.2103.11389
ec_funded: 1
external_id:
arxiv:
- '2103.11389'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/2103.11389
month: '03'
oa: 1
oa_version: Preprint
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
publication: arXiv
publication_status: submitted
related_material:
record:
- id: '9946'
relation: other
status: public
status: public
title: Formal verification of Zagier's one-sentence proof
type: preprint
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2021'
...
---
_id: '9282'
abstract:
- lang: eng
text: Several Ising-type magnetic van der Waals (vdW) materials exhibit stable magnetic
ground states. Despite these clear experimental demonstrations, a complete theoretical
and microscopic understanding of their magnetic anisotropy is still lacking. In
particular, the validity limit of identifying their one-dimensional (1-D) Ising
nature has remained uninvestigated in a quantitative way. Here we performed the
complete mapping of magnetic anisotropy for a prototypical Ising vdW magnet FePS3
for the first time. Combining torque magnetometry measurements with their magnetostatic
model analysis and the relativistic density functional total energy calculations,
we successfully constructed the three-dimensional (3-D) mappings of the magnetic
anisotropy in terms of magnetic torque and energy. The results not only quantitatively
confirm that the easy axis is perpendicular to the ab plane, but also reveal the
anisotropies within the ab, ac, and bc planes. Our approach can be applied to
the detailed quantitative study of magnetism in vdW materials.
article_number: '035011'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Muhammad
full_name: Nauman, Muhammad
id: 32c21954-2022-11eb-9d5f-af9f93c24e71
last_name: Nauman
orcid: 0000-0002-2111-4846
- first_name: Do Hoon
full_name: Kiem, Do Hoon
last_name: Kiem
- first_name: Sungmin
full_name: Lee, Sungmin
last_name: Lee
- first_name: Suhan
full_name: Son, Suhan
last_name: Son
- first_name: J-G
full_name: Park, J-G
last_name: Park
- first_name: Woun
full_name: Kang, Woun
last_name: Kang
- first_name: Myung Joon
full_name: Han, Myung Joon
last_name: Han
- first_name: Youn Jung
full_name: Jo, Youn Jung
last_name: Jo
citation:
ama: Nauman M, Kiem DH, Lee S, et al. Complete mapping of magnetic anisotropy for
prototype Ising van der Waals FePS3. 2D Materials. 2021;8(3). doi:10.1088/2053-1583/abeed3
apa: Nauman, M., Kiem, D. H., Lee, S., Son, S., Park, J.-G., Kang, W., … Jo, Y.
J. (2021). Complete mapping of magnetic anisotropy for prototype Ising van der
Waals FePS3. 2D Materials. IOP Publishing. https://doi.org/10.1088/2053-1583/abeed3
chicago: Nauman, Muhammad, Do Hoon Kiem, Sungmin Lee, Suhan Son, J-G Park, Woun
Kang, Myung Joon Han, and Youn Jung Jo. “Complete Mapping of Magnetic Anisotropy
for Prototype Ising van Der Waals FePS3.” 2D Materials. IOP Publishing,
2021. https://doi.org/10.1088/2053-1583/abeed3.
ieee: M. Nauman et al., “Complete mapping of magnetic anisotropy for prototype
Ising van der Waals FePS3,” 2D Materials, vol. 8, no. 3. IOP Publishing,
2021.
ista: Nauman M, Kiem DH, Lee S, Son S, Park J-G, Kang W, Han MJ, Jo YJ. 2021. Complete
mapping of magnetic anisotropy for prototype Ising van der Waals FePS3. 2D Materials.
8(3), 035011.
mla: Nauman, Muhammad, et al. “Complete Mapping of Magnetic Anisotropy for Prototype
Ising van Der Waals FePS3.” 2D Materials, vol. 8, no. 3, 035011, IOP Publishing,
2021, doi:10.1088/2053-1583/abeed3.
short: M. Nauman, D.H. Kiem, S. Lee, S. Son, J.-G. Park, W. Kang, M.J. Han, Y.J.
Jo, 2D Materials 8 (2021).
date_created: 2021-03-23T07:10:17Z
date_published: 2021-04-06T00:00:00Z
date_updated: 2021-12-01T10:36:56Z
day: '06'
department:
- _id: KiMo
doi: 10.1088/2053-1583/abeed3
extern: '1'
external_id:
arxiv:
- '2103.09029'
intvolume: ' 8'
issue: '3'
keyword:
- Mechanical Engineering
- General Materials Science
- Mechanics of Materials
- General Chemistry
- Condensed Matter Physics
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/2103.09029
month: '04'
oa: 1
oa_version: Preprint
publication: 2D Materials
publication_identifier:
issn:
- 2053-1583
publication_status: published
publisher: IOP Publishing
quality_controlled: '1'
status: public
title: Complete mapping of magnetic anisotropy for prototype Ising van der Waals FePS3
type: journal_article
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
volume: 8
year: '2021'
...
---
_id: '9283'
abstract:
- lang: eng
text: Gene expression levels are influenced by multiple coexisting molecular mechanisms.
Some of these interactions such as those of transcription factors and promoters
have been studied extensively. However, predicting phenotypes of gene regulatory
networks (GRNs) remains a major challenge. Here, we use a well-defined synthetic
GRN to study in Escherichia coli how network phenotypes depend on local genetic
context, i.e. the genetic neighborhood of a transcription factor and its relative
position. We show that one GRN with fixed topology can display not only quantitatively
but also qualitatively different phenotypes, depending solely on the local genetic
context of its components. Transcriptional read-through is the main molecular
mechanism that places one transcriptional unit (TU) within two separate regulons
without the need for complex regulatory sequences. We propose that relative order
of individual TUs, with its potential for combinatorial complexity, plays an important
role in shaping phenotypes of GRNs.
acknowledgement: "We thank J Bollback, L Hurst, M Lagator, C Nizak, O Rivoire, M Savageau,
G Tkacik, and B Vicozo\r\nfor helpful discussions; A Dolinar and A Greshnova for
technical assistance; T Bollenbach for supplying the strain JW0336; C Rusnac, and
members of the Guet lab for comments. The research leading to these results has
received funding from the People Programme (Marie Curie Actions) of the European
Union’s Seventh Framework Programme (FP7/2007-2013) under REA grant agreement n˚\r\n628377
(ANS) and an Austrian Science Fund (FWF) grant n˚ I 3901-B32 (CCG)."
article_number: e65993
article_processing_charge: Yes
article_type: original
author:
- first_name: Anna A
full_name: Nagy-Staron, Anna A
id: 3ABC5BA6-F248-11E8-B48F-1D18A9856A87
last_name: Nagy-Staron
orcid: 0000-0002-1391-8377
- first_name: Kathrin
full_name: Tomasek, Kathrin
id: 3AEC8556-F248-11E8-B48F-1D18A9856A87
last_name: Tomasek
orcid: 0000-0003-3768-877X
- first_name: Caroline
full_name: Caruso Carter, Caroline
last_name: Caruso Carter
- first_name: Elisabeth
full_name: Sonnleitner, Elisabeth
last_name: Sonnleitner
- first_name: Bor
full_name: Kavcic, Bor
id: 350F91D2-F248-11E8-B48F-1D18A9856A87
last_name: Kavcic
orcid: 0000-0001-6041-254X
- first_name: Tiago
full_name: Paixão, Tiago
last_name: Paixão
- first_name: Calin C
full_name: Guet, Calin C
id: 47F8433E-F248-11E8-B48F-1D18A9856A87
last_name: Guet
orcid: 0000-0001-6220-2052
citation:
ama: Nagy-Staron AA, Tomasek K, Caruso Carter C, et al. Local genetic context shapes
the function of a gene regulatory network. eLife. 2021;10. doi:10.7554/elife.65993
apa: Nagy-Staron, A. A., Tomasek, K., Caruso Carter, C., Sonnleitner, E., Kavcic,
B., Paixão, T., & Guet, C. C. (2021). Local genetic context shapes the function
of a gene regulatory network. ELife. eLife Sciences Publications. https://doi.org/10.7554/elife.65993
chicago: Nagy-Staron, Anna A, Kathrin Tomasek, Caroline Caruso Carter, Elisabeth
Sonnleitner, Bor Kavcic, Tiago Paixão, and Calin C Guet. “Local Genetic Context
Shapes the Function of a Gene Regulatory Network.” ELife. eLife Sciences
Publications, 2021. https://doi.org/10.7554/elife.65993.
ieee: A. A. Nagy-Staron et al., “Local genetic context shapes the function
of a gene regulatory network,” eLife, vol. 10. eLife Sciences Publications,
2021.
ista: Nagy-Staron AA, Tomasek K, Caruso Carter C, Sonnleitner E, Kavcic B, Paixão
T, Guet CC. 2021. Local genetic context shapes the function of a gene regulatory
network. eLife. 10, e65993.
mla: Nagy-Staron, Anna A., et al. “Local Genetic Context Shapes the Function of
a Gene Regulatory Network.” ELife, vol. 10, e65993, eLife Sciences Publications,
2021, doi:10.7554/elife.65993.
short: A.A. Nagy-Staron, K. Tomasek, C. Caruso Carter, E. Sonnleitner, B. Kavcic,
T. Paixão, C.C. Guet, ELife 10 (2021).
date_created: 2021-03-23T10:11:46Z
date_published: 2021-03-08T00:00:00Z
date_updated: 2024-02-21T12:41:57Z
day: '08'
ddc:
- '570'
department:
- _id: GaTk
- _id: CaGu
doi: 10.7554/elife.65993
ec_funded: 1
external_id:
isi:
- '000631050900001'
file:
- access_level: open_access
checksum: 3c2f44058c2dd45a5a1027f09d263f8e
content_type: application/pdf
creator: bkavcic
date_created: 2021-03-23T10:12:58Z
date_updated: 2021-03-23T10:12:58Z
file_id: '9284'
file_name: elife-65993-v2.pdf
file_size: 1390469
relation: main_file
success: 1
file_date_updated: 2021-03-23T10:12:58Z
has_accepted_license: '1'
intvolume: ' 10'
isi: 1
keyword:
- Genetics and Molecular Biology
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
project:
- _id: 2517526A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '628377'
name: 'The Systems Biology of Transcriptional Read-Through in Bacteria: from Synthetic
Networks to Genomic Studies'
- _id: 268BFA92-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: I03901
name: 'CyberCircuits: Cybergenetic circuits to test composability of gene networks'
publication: eLife
publication_identifier:
issn:
- 2050-084X
publication_status: published
publisher: eLife Sciences Publications
quality_controlled: '1'
related_material:
record:
- id: '8951'
relation: research_data
status: public
status: public
title: Local genetic context shapes the function of a gene regulatory network
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 10
year: '2021'
...
---
_id: '9287'
abstract:
- lang: eng
text: "The phytohormone auxin and its directional transport through tissues are
intensively studied. However, a mechanistic understanding of auxin-mediated feedback
on endocytosis and polar distribution of PIN auxin transporters remains limited
due to contradictory observations and interpretations. Here, we used state-of-the-art
methods to reexamine the\r\nauxin effects on PIN endocytic trafficking. We used
high auxin concentrations or longer treatments versus lower concentrations and
shorter treatments of natural (IAA) and synthetic (NAA) auxins to distinguish
between specific and nonspecific effects. Longer treatments of both auxins interfere
with Brefeldin A-mediated intracellular PIN2 accumulation and also with general
aggregation of endomembrane compartments. NAA treatment decreased the internalization
of the endocytic tracer dye, FM4-64; however, NAA treatment also affected the
number, distribution, and compartment identity of the early endosome/trans-Golgi
network (EE/TGN), rendering the FM4-64 endocytic assays at high NAA concentrations
unreliable. To circumvent these nonspecific effects of NAA and IAA affecting the
endomembrane system, we opted for alternative approaches visualizing the endocytic
events directly at the plasma membrane (PM). Using Total Internal Reflection Fluorescence
(TIRF) microscopy, we saw no significant effects of IAA or NAA treatments on the
incidence and dynamics of clathrin foci, implying that these treatments do not
affect the overall endocytosis rate. However, both NAA and IAA at low concentrations
rapidly and specifically promoted endocytosis of photo-converted PIN2 from the
PM. These analyses identify a specific effect of NAA and IAA on PIN2 endocytosis,
thus contributing to its\r\npolarity maintenance and furthermore illustrate that
high auxin levels have nonspecific effects on trafficking and endomembrane compartments. "
acknowledged_ssus:
- _id: M-Shop
- _id: Bio
acknowledgement: 'We thank Ivan Kulik for developing the Chip’n’Dale apparatus with
Lanxin Li; the IST machine shop and the Bioimaging facility for their excellent
support; Matouš Glanc and Matyáš Fendrych for their valuable discussions and help;
Barbara Casillas-Perez for her help with statistics. This project has received funding
from the European Research Council (ERC) under the European Union''s Horizon 2020
research and innovation program (grant agreement No 742985). A.J. is supported by
funding from the Austrian Science Fund (FWF): I3630B25 to J.F. '
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: Madhumitha
full_name: Narasimhan, Madhumitha
id: 44BF24D0-F248-11E8-B48F-1D18A9856A87
last_name: Narasimhan
orcid: 0000-0002-8600-0671
- first_name: Michelle C
full_name: Gallei, Michelle C
id: 35A03822-F248-11E8-B48F-1D18A9856A87
last_name: Gallei
orcid: 0000-0003-1286-7368
- first_name: Shutang
full_name: Tan, Shutang
id: 2DE75584-F248-11E8-B48F-1D18A9856A87
last_name: Tan
orcid: 0000-0002-0471-8285
- first_name: Alexander J
full_name: Johnson, Alexander J
id: 46A62C3A-F248-11E8-B48F-1D18A9856A87
last_name: Johnson
orcid: 0000-0002-2739-8843
- first_name: Inge
full_name: Verstraeten, Inge
id: 362BF7FE-F248-11E8-B48F-1D18A9856A87
last_name: Verstraeten
orcid: 0000-0001-7241-2328
- first_name: Lanxin
full_name: Li, Lanxin
id: 367EF8FA-F248-11E8-B48F-1D18A9856A87
last_name: Li
orcid: 0000-0002-5607-272X
- first_name: Lesia
full_name: Rodriguez Solovey, Lesia
id: 3922B506-F248-11E8-B48F-1D18A9856A87
last_name: Rodriguez Solovey
orcid: 0000-0002-7244-7237
- first_name: Huibin
full_name: Han, Huibin
id: 31435098-F248-11E8-B48F-1D18A9856A87
last_name: Han
- first_name: E
full_name: Himschoot, E
last_name: Himschoot
- first_name: R
full_name: Wang, R
last_name: Wang
- first_name: S
full_name: Vanneste, S
last_name: Vanneste
- first_name: J
full_name: Sánchez-Simarro, J
last_name: Sánchez-Simarro
- first_name: F
full_name: Aniento, F
last_name: Aniento
- first_name: Maciek
full_name: Adamowski, Maciek
id: 45F536D2-F248-11E8-B48F-1D18A9856A87
last_name: Adamowski
orcid: 0000-0001-6463-5257
- first_name: Jiří
full_name: Friml, Jiří
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
citation:
ama: Narasimhan M, Gallei MC, Tan S, et al. Systematic analysis of specific and
nonspecific auxin effects on endocytosis and trafficking. Plant Physiology.
2021;186(2):1122–1142. doi:10.1093/plphys/kiab134
apa: Narasimhan, M., Gallei, M. C., Tan, S., Johnson, A. J., Verstraeten, I., Li,
L., … Friml, J. (2021). Systematic analysis of specific and nonspecific auxin
effects on endocytosis and trafficking. Plant Physiology. Oxford University
Press. https://doi.org/10.1093/plphys/kiab134
chicago: Narasimhan, Madhumitha, Michelle C Gallei, Shutang Tan, Alexander J Johnson,
Inge Verstraeten, Lanxin Li, Lesia Rodriguez Solovey, et al. “Systematic Analysis
of Specific and Nonspecific Auxin Effects on Endocytosis and Trafficking.” Plant
Physiology. Oxford University Press, 2021. https://doi.org/10.1093/plphys/kiab134.
ieee: M. Narasimhan et al., “Systematic analysis of specific and nonspecific
auxin effects on endocytosis and trafficking,” Plant Physiology, vol. 186,
no. 2. Oxford University Press, pp. 1122–1142, 2021.
ista: Narasimhan M, Gallei MC, Tan S, Johnson AJ, Verstraeten I, Li L, Rodriguez
Solovey L, Han H, Himschoot E, Wang R, Vanneste S, Sánchez-Simarro J, Aniento
F, Adamowski M, Friml J. 2021. Systematic analysis of specific and nonspecific
auxin effects on endocytosis and trafficking. Plant Physiology. 186(2), 1122–1142.
mla: Narasimhan, Madhumitha, et al. “Systematic Analysis of Specific and Nonspecific
Auxin Effects on Endocytosis and Trafficking.” Plant Physiology, vol. 186,
no. 2, Oxford University Press, 2021, pp. 1122–1142, doi:10.1093/plphys/kiab134.
short: M. Narasimhan, M.C. Gallei, S. Tan, A.J. Johnson, I. Verstraeten, L. Li,
L. Rodriguez Solovey, H. Han, E. Himschoot, R. Wang, S. Vanneste, J. Sánchez-Simarro,
F. Aniento, M. Adamowski, J. Friml, Plant Physiology 186 (2021) 1122–1142.
date_created: 2021-03-26T12:08:38Z
date_published: 2021-06-01T00:00:00Z
date_updated: 2024-10-29T10:22:43Z
day: '01'
ddc:
- '580'
department:
- _id: JiFr
doi: 10.1093/plphys/kiab134
ec_funded: 1
external_id:
isi:
- '000671555900031'
pmid:
- '33734402'
file:
- access_level: open_access
checksum: 532bb9469d3b665907f06df8c383eade
content_type: application/pdf
creator: cziletti
date_created: 2021-11-11T15:07:51Z
date_updated: 2021-11-11T15:07:51Z
file_id: '10273'
file_name: 2021_PlantPhysio_Narasimhan.pdf
file_size: 2289127
relation: main_file
success: 1
file_date_updated: 2021-11-11T15:07:51Z
has_accepted_license: '1'
intvolume: ' 186'
isi: 1
issue: '2'
language:
- iso: eng
month: '06'
oa: 1
oa_version: Published Version
page: 1122–1142
pmid: 1
project:
- _id: 261099A6-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '742985'
name: Tracing Evolution of Auxin Transport and Polarity in Plants
- _id: 26538374-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: I03630
name: Molecular mechanisms of endocytic cargo recognition in plants
publication: Plant Physiology
publication_identifier:
eissn:
- 1532-2548
issn:
- 0032-0889
publication_status: published
publisher: Oxford University Press
quality_controlled: '1'
related_material:
link:
- relation: erratum
url: 10.1093/plphys/kiab380
record:
- id: '11626'
relation: dissertation_contains
status: public
- id: '10083'
relation: dissertation_contains
status: public
status: public
title: Systematic analysis of specific and nonspecific auxin effects on endocytosis
and trafficking
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 186
year: '2021'
...
---
_id: '9288'
abstract:
- lang: eng
text: "• The phenylpropanoid pathway serves a central role in plant metabolism,
providing numerous compounds involved in diverse physiological processes. Most
carbon entering the pathway is incorporated into lignin. Although several phenylpropanoid
pathway mutants show seedling growth arrest, the role for lignin in seedling growth
and development is unexplored.\r\n• We use complementary pharmacological and genetic
approaches to block CINNAMATE‐4‐HYDROXYLASE (C4H) functionality in Arabidopsis
seedlings and a set of molecular and biochemical techniques to investigate the
underlying phenotypes.\r\n• Blocking C4H resulted in reduced lateral rooting and
increased adventitious rooting apically in the hypocotyl. These phenotypes coincided
with an inhibition in auxin transport. The upstream accumulation in cis‐cinnamic
acid was found to likely cause polar auxin transport inhibition. Conversely, a
downstream depletion in lignin perturbed phloem‐mediated auxin transport. Restoring
lignin deposition effectively reestablished phloem transport and, accordingly,
auxin homeostasis.\r\n• Our results show that the accumulation of bioactive intermediates
and depletion in lignin jointly cause the aberrant phenotypes upon blocking C4H,
and demonstrate that proper deposition of lignin is essential for the establishment
of auxin distribution in seedlings. Our data position the phenylpropanoid pathway
and lignin in a new physiological framework, consolidating their importance in
plant growth and development."
article_processing_charge: No
article_type: original
author:
- first_name: I
full_name: El Houari, I
last_name: El Houari
- first_name: C
full_name: Van Beirs, C
last_name: Van Beirs
- first_name: HE
full_name: Arents, HE
last_name: Arents
- first_name: Huibin
full_name: Han, Huibin
id: 31435098-F248-11E8-B48F-1D18A9856A87
last_name: Han
- first_name: A
full_name: Chanoca, A
last_name: Chanoca
- first_name: D
full_name: Opdenacker, D
last_name: Opdenacker
- first_name: J
full_name: Pollier, J
last_name: Pollier
- first_name: V
full_name: Storme, V
last_name: Storme
- first_name: W
full_name: Steenackers, W
last_name: Steenackers
- first_name: M
full_name: Quareshy, M
last_name: Quareshy
- first_name: R
full_name: Napier, R
last_name: Napier
- first_name: T
full_name: Beeckman, T
last_name: Beeckman
- first_name: Jiří
full_name: Friml, Jiří
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: B
full_name: De Rybel, B
last_name: De Rybel
- first_name: W
full_name: Boerjan, W
last_name: Boerjan
- first_name: B
full_name: Vanholme, B
last_name: Vanholme
citation:
ama: El Houari I, Van Beirs C, Arents H, et al. Seedling developmental defects upon
blocking CINNAMATE-4-HYDROXYLASE are caused by perturbations in auxin transport.
New Phytologist. 2021;230(6):2275-2291. doi:10.1111/nph.17349
apa: El Houari, I., Van Beirs, C., Arents, H., Han, H., Chanoca, A., Opdenacker,
D., … Vanholme, B. (2021). Seedling developmental defects upon blocking CINNAMATE-4-HYDROXYLASE
are caused by perturbations in auxin transport. New Phytologist. Wiley.
https://doi.org/10.1111/nph.17349
chicago: El Houari, I, C Van Beirs, HE Arents, Huibin Han, A Chanoca, D Opdenacker,
J Pollier, et al. “Seedling Developmental Defects upon Blocking CINNAMATE-4-HYDROXYLASE
Are Caused by Perturbations in Auxin Transport.” New Phytologist. Wiley,
2021. https://doi.org/10.1111/nph.17349.
ieee: I. El Houari et al., “Seedling developmental defects upon blocking
CINNAMATE-4-HYDROXYLASE are caused by perturbations in auxin transport,” New
Phytologist, vol. 230, no. 6. Wiley, pp. 2275–2291, 2021.
ista: El Houari I, Van Beirs C, Arents H, Han H, Chanoca A, Opdenacker D, Pollier
J, Storme V, Steenackers W, Quareshy M, Napier R, Beeckman T, Friml J, De Rybel
B, Boerjan W, Vanholme B. 2021. Seedling developmental defects upon blocking CINNAMATE-4-HYDROXYLASE
are caused by perturbations in auxin transport. New Phytologist. 230(6), 2275–2291.
mla: El Houari, I., et al. “Seedling Developmental Defects upon Blocking CINNAMATE-4-HYDROXYLASE
Are Caused by Perturbations in Auxin Transport.” New Phytologist, vol.
230, no. 6, Wiley, 2021, pp. 2275–91, doi:10.1111/nph.17349.
short: I. El Houari, C. Van Beirs, H. Arents, H. Han, A. Chanoca, D. Opdenacker,
J. Pollier, V. Storme, W. Steenackers, M. Quareshy, R. Napier, T. Beeckman, J.
Friml, B. De Rybel, W. Boerjan, B. Vanholme, New Phytologist 230 (2021) 2275–2291.
date_created: 2021-03-26T12:09:01Z
date_published: 2021-03-17T00:00:00Z
date_updated: 2023-09-05T15:46:55Z
day: '17'
department:
- _id: JiFr
doi: 10.1111/nph.17349
external_id:
isi:
- '000639552400001'
pmid:
- '33728703'
intvolume: ' 230'
isi: 1
issue: '6'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://biblio.ugent.be/publication/8703799/file/8703800.pdf
month: '03'
oa: 1
oa_version: Published Version
page: 2275-2291
pmid: 1
publication: New Phytologist
publication_identifier:
eissn:
- 1469-8137
issn:
- 0028-646x
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Seedling developmental defects upon blocking CINNAMATE-4-HYDROXYLASE are caused
by perturbations in auxin transport
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 230
year: '2021'
...
---
_id: '9290'
abstract:
- lang: eng
text: Polar subcellular localization of the PIN exporters of the phytohormone auxin
is a key determinant of directional, intercellular auxin transport and thus a
central topic of both plant cell and developmental biology. Arabidopsis mutants
lacking PID, a kinase that phosphorylates PINs, or the MAB4/MEL proteins of unknown
molecular function display PIN polarity defects and phenocopy pin mutants, but
mechanistic insights into how these factors convey PIN polarity are missing. Here,
by combining protein biochemistry with quantitative live-cell imaging, we demonstrate
that PINs, MAB4/MELs, and AGC kinases interact in the same complex at the plasma
membrane. MAB4/MELs are recruited to the plasma membrane by the PINs and in concert
with the AGC kinases maintain PIN polarity through limiting lateral diffusion-based
escape of PINs from the polar domain. The PIN-MAB4/MEL-PID protein complex has
self-reinforcing properties thanks to positive feedback between AGC kinase-mediated
PIN phosphorylation and MAB4/MEL recruitment. We thus uncover the molecular mechanism
by which AGC kinases and MAB4/MEL proteins regulate PIN localization and plant
development.
acknowledged_ssus:
- _id: Bio
acknowledgement: We acknowledge Ben Scheres, Christian Luschnig, and Claus Schwechheimer
for sharing published material. We thank Monika Hrtyan and Dorota Jaworska at IST
Austria and Gerda Lamers and Ward de Winter at IBL Netherlands for technical assistance;
Corinna Hartinger, Jakub Hajný, Lesia Rodriguez, Mingyue Li, and Lindy Abas for
experimental support; and the Bioimaging Facility at IST Austria and the Bioimaging
Core at VIB for imaging support. We are grateful to Christian Luschnig, Lindy Abas,
and Roman Pleskot for valuable discussions. We also acknowledge the EMBO for supporting
M.G. with a long-term fellowship ( ALTF 1005-2019 ) during the finalization and
revision of this manuscript in the laboratory of B.D.R., and we thank R. Pierik
for allowing K.V.G. to work on this manuscript during a postdoc in his laboratory
at Utrecht University. This work was supported by grants from the European Research
Council under the European Union’s Seventh Framework Programme (ERC grant agreements
742985 to J.F., 714055 to B.D.R., and 803048 to M.F.), the Austrian Science Fund
(FWF; I 3630-B25 to J.F.), Chemical Sciences (partly) financed by the Dutch Research
Council (NWO-CW TOP 700.58.301 to R.O.), the Dutch Research Council (NWO-VICI 865.17.002
to R. Pierik), Grants-in-Aid from the Ministry of Education, Culture, Sports, Science
and Technology, Japan (KAKENHI grant 17K17595 to S.N.), the Ministry of Education,
Youth and Sports of the Czech Republic (MŠMT project NPUI-LO1417 ), and a China
Scholarship Council (to X.W.).
article_processing_charge: No
article_type: original
author:
- first_name: Matous
full_name: Glanc, Matous
id: 1AE1EA24-02D0-11E9-9BAA-DAF4881429F2
last_name: Glanc
orcid: 0000-0003-0619-7783
- first_name: K
full_name: Van Gelderen, K
last_name: Van Gelderen
- first_name: Lukas
full_name: Hörmayer, Lukas
id: 2EEE7A2A-F248-11E8-B48F-1D18A9856A87
last_name: Hörmayer
orcid: 0000-0001-8295-2926
- first_name: Shutang
full_name: Tan, Shutang
id: 2DE75584-F248-11E8-B48F-1D18A9856A87
last_name: Tan
orcid: 0000-0002-0471-8285
- first_name: S
full_name: Naramoto, S
last_name: Naramoto
- first_name: Xixi
full_name: Zhang, Xixi
id: 61A66458-47E9-11EA-85BA-8AEAAF14E49A
last_name: Zhang
orcid: 0000-0001-7048-4627
- first_name: David
full_name: Domjan, David
id: C684CD7A-257E-11EA-9B6F-D8588B4F947F
last_name: Domjan
orcid: 0000-0003-2267-106X
- first_name: L
full_name: Vcelarova, L
last_name: Vcelarova
- first_name: Robert
full_name: Hauschild, Robert
id: 4E01D6B4-F248-11E8-B48F-1D18A9856A87
last_name: Hauschild
orcid: 0000-0001-9843-3522
- first_name: Alexander J
full_name: Johnson, Alexander J
id: 46A62C3A-F248-11E8-B48F-1D18A9856A87
last_name: Johnson
orcid: 0000-0002-2739-8843
- first_name: E
full_name: de Koning, E
last_name: de Koning
- first_name: M
full_name: van Dop, M
last_name: van Dop
- first_name: E
full_name: Rademacher, E
last_name: Rademacher
- first_name: S
full_name: Janson, S
last_name: Janson
- first_name: X
full_name: Wei, X
last_name: Wei
- first_name: Gergely
full_name: Molnar, Gergely
id: 34F1AF46-F248-11E8-B48F-1D18A9856A87
last_name: Molnar
- first_name: Matyas
full_name: Fendrych, Matyas
id: 43905548-F248-11E8-B48F-1D18A9856A87
last_name: Fendrych
orcid: 0000-0002-9767-8699
- first_name: B
full_name: De Rybel, B
last_name: De Rybel
- first_name: R
full_name: Offringa, R
last_name: Offringa
- first_name: Jiří
full_name: Friml, Jiří
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
citation:
ama: Glanc M, Van Gelderen K, Hörmayer L, et al. AGC kinases and MAB4/MEL proteins
maintain PIN polarity by limiting lateral diffusion in plant cells. Current
Biology. 2021;31(9):1918-1930. doi:10.1016/j.cub.2021.02.028
apa: Glanc, M., Van Gelderen, K., Hörmayer, L., Tan, S., Naramoto, S., Zhang, X.,
… Friml, J. (2021). AGC kinases and MAB4/MEL proteins maintain PIN polarity by
limiting lateral diffusion in plant cells. Current Biology. Elsevier. https://doi.org/10.1016/j.cub.2021.02.028
chicago: Glanc, Matous, K Van Gelderen, Lukas Hörmayer, Shutang Tan, S Naramoto,
Xixi Zhang, David Domjan, et al. “AGC Kinases and MAB4/MEL Proteins Maintain PIN
Polarity by Limiting Lateral Diffusion in Plant Cells.” Current Biology.
Elsevier, 2021. https://doi.org/10.1016/j.cub.2021.02.028.
ieee: M. Glanc et al., “AGC kinases and MAB4/MEL proteins maintain PIN polarity
by limiting lateral diffusion in plant cells,” Current Biology, vol. 31,
no. 9. Elsevier, pp. 1918–1930, 2021.
ista: Glanc M, Van Gelderen K, Hörmayer L, Tan S, Naramoto S, Zhang X, Domjan D,
Vcelarova L, Hauschild R, Johnson AJ, de Koning E, van Dop M, Rademacher E, Janson
S, Wei X, Molnar G, Fendrych M, De Rybel B, Offringa R, Friml J. 2021. AGC kinases
and MAB4/MEL proteins maintain PIN polarity by limiting lateral diffusion in plant
cells. Current Biology. 31(9), 1918–1930.
mla: Glanc, Matous, et al. “AGC Kinases and MAB4/MEL Proteins Maintain PIN Polarity
by Limiting Lateral Diffusion in Plant Cells.” Current Biology, vol. 31,
no. 9, Elsevier, 2021, pp. 1918–30, doi:10.1016/j.cub.2021.02.028.
short: M. Glanc, K. Van Gelderen, L. Hörmayer, S. Tan, S. Naramoto, X. Zhang, D.
Domjan, L. Vcelarova, R. Hauschild, A.J. Johnson, E. de Koning, M. van Dop, E.
Rademacher, S. Janson, X. Wei, G. Molnar, M. Fendrych, B. De Rybel, R. Offringa,
J. Friml, Current Biology 31 (2021) 1918–1930.
date_created: 2021-03-26T12:09:33Z
date_published: 2021-03-10T00:00:00Z
date_updated: 2023-09-05T13:03:34Z
day: '10'
ddc:
- '580'
department:
- _id: JiFr
doi: 10.1016/j.cub.2021.02.028
ec_funded: 1
external_id:
isi:
- '000653077800004'
pmid:
- '33705718'
file:
- access_level: open_access
checksum: b1723040ecfd8c81194185472eb62546
content_type: application/pdf
creator: dernst
date_created: 2021-04-01T10:53:42Z
date_updated: 2021-04-01T10:53:42Z
file_id: '9303'
file_name: 2021_CurrentBiology_Glanc.pdf
file_size: 4324371
relation: main_file
success: 1
file_date_updated: 2021-04-01T10:53:42Z
has_accepted_license: '1'
intvolume: ' 31'
isi: 1
issue: '9'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
page: 1918-1930
pmid: 1
project:
- _id: 261099A6-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '742985'
name: Tracing Evolution of Auxin Transport and Polarity in Plants
- _id: 26538374-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: I03630
name: Molecular mechanisms of endocytic cargo recognition in plants
publication: Current Biology
publication_identifier:
eissn:
- 1879-0445
issn:
- 0960-9822
publication_status: published
publisher: Elsevier
quality_controlled: '1'
status: public
title: AGC kinases and MAB4/MEL proteins maintain PIN polarity by limiting lateral
diffusion in plant cells
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 31
year: '2021'
...
---
_id: '9291'
abstract:
- lang: eng
text: "This .zip File contains the transport data for figures presented in the main
text and supplementary material of \"Enhancement of Proximity Induced Superconductivity
in Planar Germanium\" by K. Aggarwal, et. al. \r\nThe measurements were done using
Labber Software and the data is stored in the hdf5 file format. The files can
be opened using either the Labber Log Browser (https://labber.org/overview/) or
Labber Python API (http://labber.org/online-doc/api/LogFile.html)."
article_processing_charge: No
author:
- first_name: Georgios
full_name: Katsaros, Georgios
id: 38DB5788-F248-11E8-B48F-1D18A9856A87
last_name: Katsaros
orcid: 0000-0001-8342-202X
citation:
ama: 'Katsaros G. Raw transport data for: Enhancement of proximity induced superconductivity
in planar germanium. 2021. doi:10.15479/AT:ISTA:9291'
apa: 'Katsaros, G. (2021). Raw transport data for: Enhancement of proximity induced
superconductivity in planar germanium. Institute of Science and Technology Austria.
https://doi.org/10.15479/AT:ISTA:9291'
chicago: 'Katsaros, Georgios. “Raw Transport Data for: Enhancement of Proximity
Induced Superconductivity in Planar Germanium.” Institute of Science and Technology
Austria, 2021. https://doi.org/10.15479/AT:ISTA:9291.'
ieee: 'G. Katsaros, “Raw transport data for: Enhancement of proximity induced superconductivity
in planar germanium.” Institute of Science and Technology Austria, 2021.'
ista: 'Katsaros G. 2021. Raw transport data for: Enhancement of proximity induced
superconductivity in planar germanium, Institute of Science and Technology Austria,
10.15479/AT:ISTA:9291.'
mla: 'Katsaros, Georgios. Raw Transport Data for: Enhancement of Proximity Induced
Superconductivity in Planar Germanium. Institute of Science and Technology
Austria, 2021, doi:10.15479/AT:ISTA:9291.'
short: G. Katsaros, (2021).
date_created: 2021-03-27T13:47:49Z
date_published: 2021-03-29T00:00:00Z
date_updated: 2024-02-21T12:37:14Z
day: '29'
ddc:
- '530'
department:
- _id: GeKa
doi: 10.15479/AT:ISTA:9291
file:
- access_level: open_access
checksum: 635df3c08fc13c3dac008cd421aefbe4
content_type: application/x-zip-compressed
creator: gkatsaro
date_created: 2021-03-27T13:46:17Z
date_updated: 2021-03-27T13:46:17Z
file_id: '9292'
file_name: Raw Data- Enhancement of Superconductivity in a Planar Ge hole gas.zip
file_size: 10616071
relation: main_file
success: 1
- access_level: open_access
checksum: 12b3ca69ae7509a346711baae0b02a75
content_type: text/plain
creator: dernst
date_created: 2021-04-01T07:52:56Z
date_updated: 2021-04-01T07:52:56Z
file_id: '9302'
file_name: README.txt
file_size: 470
relation: main_file
success: 1
file_date_updated: 2021-04-01T07:52:56Z
has_accepted_license: '1'
license: https://creativecommons.org/publicdomain/zero/1.0/
month: '03'
oa: 1
oa_version: Published Version
publisher: Institute of Science and Technology Austria
status: public
title: 'Raw transport data for: Enhancement of proximity induced superconductivity
in planar germanium'
tmp:
image: /images/cc_0.png
legal_code_url: https://creativecommons.org/publicdomain/zero/1.0/legalcode
name: Creative Commons Public Domain Dedication (CC0 1.0)
short: CC0 (1.0)
type: research_data
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2021'
...
---
_id: '9293'
abstract:
- lang: eng
text: 'We consider planning problems for graphs, Markov Decision Processes (MDPs),
and games on graphs in an explicit state space. While graphs represent the most
basic planning model, MDPs represent interaction with nature and games on graphs
represent interaction with an adversarial environment. We consider two planning
problems with k different target sets: (a) the coverage problem asks whether there
is a plan for each individual target set; and (b) the sequential target reachability
problem asks whether the targets can be reached in a given sequence. For the coverage
problem, we present a linear-time algorithm for graphs, and quadratic conditional
lower bound for MDPs and games on graphs. For the sequential target problem, we
present a linear-time algorithm for graphs, a sub-quadratic algorithm for MDPs,
and a quadratic conditional lower bound for games on graphs. Our results with
conditional lower bounds, based on the boolean matrix multiplication (BMM) conjecture
and strong exponential time hypothesis (SETH), establish (i) model-separation
results showing that for the coverage problem MDPs and games on graphs are harder
than graphs, and for the sequential reachability problem games on graphs are harder
than MDPs and graphs; and (ii) problem-separation results showing that for MDPs
the coverage problem is harder than the sequential target problem.'
article_number: '103499'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Krishnendu
full_name: Chatterjee, Krishnendu
id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
last_name: Chatterjee
orcid: 0000-0002-4561-241X
- first_name: Wolfgang
full_name: Dvořák, Wolfgang
last_name: Dvořák
- first_name: Monika H
full_name: Henzinger, Monika H
id: 540c9bbd-f2de-11ec-812d-d04a5be85630
last_name: Henzinger
orcid: 0000-0002-5008-6530
- first_name: Alexander
full_name: Svozil, Alexander
last_name: Svozil
citation:
ama: Chatterjee K, Dvořák W, Henzinger MH, Svozil A. Algorithms and conditional
lower bounds for planning problems. Artificial Intelligence. 2021;297(8).
doi:10.1016/j.artint.2021.103499
apa: Chatterjee, K., Dvořák, W., Henzinger, M. H., & Svozil, A. (2021). Algorithms
and conditional lower bounds for planning problems. Artificial Intelligence.
Elsevier. https://doi.org/10.1016/j.artint.2021.103499
chicago: Chatterjee, Krishnendu, Wolfgang Dvořák, Monika H Henzinger, and Alexander
Svozil. “Algorithms and Conditional Lower Bounds for Planning Problems.” Artificial
Intelligence. Elsevier, 2021. https://doi.org/10.1016/j.artint.2021.103499.
ieee: K. Chatterjee, W. Dvořák, M. H. Henzinger, and A. Svozil, “Algorithms and
conditional lower bounds for planning problems,” Artificial Intelligence,
vol. 297, no. 8. Elsevier, 2021.
ista: Chatterjee K, Dvořák W, Henzinger MH, Svozil A. 2021. Algorithms and conditional
lower bounds for planning problems. Artificial Intelligence. 297(8), 103499.
mla: Chatterjee, Krishnendu, et al. “Algorithms and Conditional Lower Bounds for
Planning Problems.” Artificial Intelligence, vol. 297, no. 8, 103499, Elsevier,
2021, doi:10.1016/j.artint.2021.103499.
short: K. Chatterjee, W. Dvořák, M.H. Henzinger, A. Svozil, Artificial Intelligence
297 (2021).
date_created: 2021-03-28T22:01:40Z
date_published: 2021-03-16T00:00:00Z
date_updated: 2023-09-26T10:41:42Z
day: '16'
department:
- _id: KrCh
doi: 10.1016/j.artint.2021.103499
external_id:
arxiv:
- '1804.07031'
isi:
- '000657537500003'
intvolume: ' 297'
isi: 1
issue: '8'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/1804.07031
month: '03'
oa: 1
oa_version: Preprint
publication: Artificial Intelligence
publication_identifier:
issn:
- 0004-3702
publication_status: published
publisher: Elsevier
quality_controlled: '1'
related_material:
record:
- id: '35'
relation: earlier_version
status: public
scopus_import: '1'
status: public
title: Algorithms and conditional lower bounds for planning problems
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 297
year: '2021'
...
---
_id: '9294'
abstract:
- lang: eng
text: In this issue of Developmental Cell, Doyle and colleagues identify periodic
anterior contraction as a characteristic feature of fibroblasts and mesenchymal
cancer cells embedded in 3D collagen gels. This contractile mechanism generates
a matrix prestrain required for crawling in fibrous 3D environments.
article_processing_charge: No
article_type: original
author:
- first_name: Florian R
full_name: Gärtner, Florian R
id: 397A88EE-F248-11E8-B48F-1D18A9856A87
last_name: Gärtner
orcid: 0000-0001-6120-3723
- first_name: Michael K
full_name: Sixt, Michael K
id: 41E9FBEA-F248-11E8-B48F-1D18A9856A87
last_name: Sixt
orcid: 0000-0002-6620-9179
citation:
ama: Gärtner FR, Sixt MK. Engaging the front wheels to drive through fibrous terrain.
Developmental Cell. 2021;56(6):723-725. doi:10.1016/j.devcel.2021.03.002
apa: Gärtner, F. R., & Sixt, M. K. (2021). Engaging the front wheels to drive
through fibrous terrain. Developmental Cell. Elsevier. https://doi.org/10.1016/j.devcel.2021.03.002
chicago: Gärtner, Florian R, and Michael K Sixt. “Engaging the Front Wheels to Drive
through Fibrous Terrain.” Developmental Cell. Elsevier, 2021. https://doi.org/10.1016/j.devcel.2021.03.002.
ieee: F. R. Gärtner and M. K. Sixt, “Engaging the front wheels to drive through
fibrous terrain,” Developmental Cell, vol. 56, no. 6. Elsevier, pp. 723–725,
2021.
ista: Gärtner FR, Sixt MK. 2021. Engaging the front wheels to drive through fibrous
terrain. Developmental Cell. 56(6), 723–725.
mla: Gärtner, Florian R., and Michael K. Sixt. “Engaging the Front Wheels to Drive
through Fibrous Terrain.” Developmental Cell, vol. 56, no. 6, Elsevier,
2021, pp. 723–25, doi:10.1016/j.devcel.2021.03.002.
short: F.R. Gärtner, M.K. Sixt, Developmental Cell 56 (2021) 723–725.
date_created: 2021-03-28T22:01:41Z
date_published: 2021-03-22T00:00:00Z
date_updated: 2023-08-07T14:26:47Z
day: '22'
department:
- _id: MiSi
doi: 10.1016/j.devcel.2021.03.002
external_id:
isi:
- '000631681200004'
pmid:
- '33756118'
intvolume: ' 56'
isi: 1
issue: '6'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://doi.org/10.1016/j.devcel.2021.03.002
month: '03'
oa: 1
oa_version: Published Version
page: 723-725
pmid: 1
publication: Developmental Cell
publication_identifier:
eissn:
- '18781551'
issn:
- '15345807'
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Engaging the front wheels to drive through fibrous terrain
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 56
year: '2021'
...
---
_id: '9295'
abstract:
- lang: eng
text: "Hill's Conjecture states that the crossing number cr(\U0001D43E\U0001D45B)
\ of the complete graph \U0001D43E\U0001D45B in the plane (equivalently, the
sphere) is 14⌊\U0001D45B2⌋⌊\U0001D45B−12⌋⌊\U0001D45B−22⌋⌊\U0001D45B−32⌋=\U0001D45B4/64+\U0001D442(\U0001D45B3)
. Moon proved that the expected number of crossings in a spherical drawing in
which the points are randomly distributed and joined by geodesics is precisely
\ \U0001D45B4/64+\U0001D442(\U0001D45B3) , thus matching asymptotically the conjectured
value of cr(\U0001D43E\U0001D45B) . Let cr\U0001D443(\U0001D43A) denote the
crossing number of a graph \U0001D43A in the projective plane. Recently, Elkies
proved that the expected number of crossings in a naturally defined random projective
plane drawing of \U0001D43E\U0001D45B is (\U0001D45B4/8\U0001D70B2)+\U0001D442(\U0001D45B3)
. In analogy with the relation of Moon's result to Hill's conjecture, Elkies asked
if lim\U0001D45B→∞ cr\U0001D443(\U0001D43E\U0001D45B)/\U0001D45B4=1/8\U0001D70B2
. We construct drawings of \U0001D43E\U0001D45B in the projective plane that
disprove this."
acknowledgement: "We thank two reviewers for their corrections and suggestions on
the original version of this\r\npaper. This project has received funding from NSERC
Grant 50503-10940-500 and from the European Union’s Horizon 2020 research and innovation
programme under the Marie SkłodowskaCurie grant agreement No 754411, IST, Klosterneuburg,
Austria."
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Alan M
full_name: Arroyo Guevara, Alan M
id: 3207FDC6-F248-11E8-B48F-1D18A9856A87
last_name: Arroyo Guevara
orcid: 0000-0003-2401-8670
- first_name: Dan
full_name: Mcquillan, Dan
last_name: Mcquillan
- first_name: R. Bruce
full_name: Richter, R. Bruce
last_name: Richter
- first_name: Gelasio
full_name: Salazar, Gelasio
last_name: Salazar
- first_name: Matthew
full_name: Sullivan, Matthew
last_name: Sullivan
citation:
ama: Arroyo Guevara AM, Mcquillan D, Richter RB, Salazar G, Sullivan M. Drawings
of complete graphs in the projective plane. Journal of Graph Theory. 2021;97(3):426-440.
doi:10.1002/jgt.22665
apa: Arroyo Guevara, A. M., Mcquillan, D., Richter, R. B., Salazar, G., & Sullivan,
M. (2021). Drawings of complete graphs in the projective plane. Journal of
Graph Theory. Wiley. https://doi.org/10.1002/jgt.22665
chicago: Arroyo Guevara, Alan M, Dan Mcquillan, R. Bruce Richter, Gelasio Salazar,
and Matthew Sullivan. “Drawings of Complete Graphs in the Projective Plane.” Journal
of Graph Theory. Wiley, 2021. https://doi.org/10.1002/jgt.22665.
ieee: A. M. Arroyo Guevara, D. Mcquillan, R. B. Richter, G. Salazar, and M. Sullivan,
“Drawings of complete graphs in the projective plane,” Journal of Graph Theory,
vol. 97, no. 3. Wiley, pp. 426–440, 2021.
ista: Arroyo Guevara AM, Mcquillan D, Richter RB, Salazar G, Sullivan M. 2021. Drawings
of complete graphs in the projective plane. Journal of Graph Theory. 97(3), 426–440.
mla: Arroyo Guevara, Alan M., et al. “Drawings of Complete Graphs in the Projective
Plane.” Journal of Graph Theory, vol. 97, no. 3, Wiley, 2021, pp. 426–40,
doi:10.1002/jgt.22665.
short: A.M. Arroyo Guevara, D. Mcquillan, R.B. Richter, G. Salazar, M. Sullivan,
Journal of Graph Theory 97 (2021) 426–440.
date_created: 2021-03-28T22:01:41Z
date_published: 2021-03-23T00:00:00Z
date_updated: 2023-08-07T14:26:15Z
day: '23'
department:
- _id: UlWa
doi: 10.1002/jgt.22665
ec_funded: 1
external_id:
arxiv:
- '2002.02287'
isi:
- '000631693200001'
intvolume: ' 97'
isi: 1
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/2002.02287
month: '03'
oa: 1
oa_version: Preprint
page: 426-440
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
publication: Journal of Graph Theory
publication_identifier:
eissn:
- 1097-0118
issn:
- 0364-9024
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Drawings of complete graphs in the projective plane
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 97
year: '2021'
...
---
_id: '9296'
abstract:
- lang: eng
text: ' matching is compatible to two or more labeled point sets of size n with
labels {1,…,n} if its straight-line drawing on each of these point sets is
crossing-free. We study the maximum number of edges in a matching compatible to
two or more labeled point sets in general position in the plane. We show that
for any two labeled convex sets of n points there exists a compatible matching
with ⌊2n−−√⌋ edges. More generally, for any ℓ labeled point sets we construct
compatible matchings of size Ω(n1/ℓ) . As a corresponding upper bound, we use
probabilistic arguments to show that for any ℓ given sets of n points there
exists a labeling of each set such that the largest compatible matching has O(n2/(ℓ+1)) edges.
Finally, we show that Θ(logn) copies of any set of n points are necessary and
sufficient for the existence of a labeling such that any compatible matching consists
only of a single edge.'
acknowledgement: 'A.A. funded by the Marie Skłodowska-Curie grant agreement No. 754411.
Z.M. partially funded by Wittgenstein Prize, Austrian Science Fund (FWF), grant
no. Z 342-N31. I.P., D.P., and B.V. partially supported by FWF within the collaborative
DACH project Arrangements and Drawings as FWF project I 3340-N35. A.P. supported
by a Schrödinger fellowship of the FWF: J-3847-N35. J.T. partially supported by
ERC Start grant no. (279307: Graph Games), FWF grant no. P23499-N23 and S11407-N23
(RiSE).'
alternative_title:
- LNCS
article_processing_charge: No
arxiv: 1
author:
- first_name: Oswin
full_name: Aichholzer, Oswin
last_name: Aichholzer
- first_name: Alan M
full_name: Arroyo Guevara, Alan M
id: 3207FDC6-F248-11E8-B48F-1D18A9856A87
last_name: Arroyo Guevara
orcid: 0000-0003-2401-8670
- first_name: Zuzana
full_name: Masárová, Zuzana
id: 45CFE238-F248-11E8-B48F-1D18A9856A87
last_name: Masárová
orcid: 0000-0002-6660-1322
- first_name: Irene
full_name: Parada, Irene
last_name: Parada
- first_name: Daniel
full_name: Perz, Daniel
last_name: Perz
- first_name: Alexander
full_name: Pilz, Alexander
last_name: Pilz
- first_name: Josef
full_name: Tkadlec, Josef
id: 3F24CCC8-F248-11E8-B48F-1D18A9856A87
last_name: Tkadlec
orcid: 0000-0002-1097-9684
- first_name: Birgit
full_name: Vogtenhuber, Birgit
last_name: Vogtenhuber
citation:
ama: 'Aichholzer O, Arroyo Guevara AM, Masárová Z, et al. On compatible matchings.
In: 15th International Conference on Algorithms and Computation. Vol 12635.
Springer Nature; 2021:221-233. doi:10.1007/978-3-030-68211-8_18'
apa: 'Aichholzer, O., Arroyo Guevara, A. M., Masárová, Z., Parada, I., Perz, D.,
Pilz, A., … Vogtenhuber, B. (2021). On compatible matchings. In 15th International
Conference on Algorithms and Computation (Vol. 12635, pp. 221–233). Yangon,
Myanmar: Springer Nature. https://doi.org/10.1007/978-3-030-68211-8_18'
chicago: Aichholzer, Oswin, Alan M Arroyo Guevara, Zuzana Masárová, Irene Parada,
Daniel Perz, Alexander Pilz, Josef Tkadlec, and Birgit Vogtenhuber. “On Compatible
Matchings.” In 15th International Conference on Algorithms and Computation,
12635:221–33. Springer Nature, 2021. https://doi.org/10.1007/978-3-030-68211-8_18.
ieee: O. Aichholzer et al., “On compatible matchings,” in 15th International
Conference on Algorithms and Computation, Yangon, Myanmar, 2021, vol. 12635,
pp. 221–233.
ista: 'Aichholzer O, Arroyo Guevara AM, Masárová Z, Parada I, Perz D, Pilz A, Tkadlec
J, Vogtenhuber B. 2021. On compatible matchings. 15th International Conference
on Algorithms and Computation. WALCOM: Algorithms and Computation, LNCS, vol.
12635, 221–233.'
mla: Aichholzer, Oswin, et al. “On Compatible Matchings.” 15th International
Conference on Algorithms and Computation, vol. 12635, Springer Nature, 2021,
pp. 221–33, doi:10.1007/978-3-030-68211-8_18.
short: O. Aichholzer, A.M. Arroyo Guevara, Z. Masárová, I. Parada, D. Perz, A. Pilz,
J. Tkadlec, B. Vogtenhuber, in:, 15th International Conference on Algorithms and
Computation, Springer Nature, 2021, pp. 221–233.
conference:
end_date: 2021-03-02
location: Yangon, Myanmar
name: 'WALCOM: Algorithms and Computation'
start_date: 2021-02-28
date_created: 2021-03-28T22:01:41Z
date_published: 2021-02-16T00:00:00Z
date_updated: 2023-02-21T16:33:44Z
day: '16'
department:
- _id: UlWa
- _id: HeEd
- _id: KrCh
doi: 10.1007/978-3-030-68211-8_18
ec_funded: 1
external_id:
arxiv:
- '2101.03928'
intvolume: ' 12635'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://arxiv.org/abs/2101.03928
month: '02'
oa: 1
oa_version: Preprint
page: 221-233
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
call_identifier: H2020
grant_number: '754411'
name: ISTplus - Postdoctoral Fellowships
- _id: 268116B8-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: Z00342
name: The Wittgenstein Prize
- _id: 2581B60A-B435-11E9-9278-68D0E5697425
call_identifier: FP7
grant_number: '279307'
name: 'Quantitative Graph Games: Theory and Applications'
- _id: 2584A770-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: P 23499-N23
name: Modern Graph Algorithmic Techniques in Formal Verification
- _id: 25863FF4-B435-11E9-9278-68D0E5697425
call_identifier: FWF
grant_number: S11407
name: Game Theory
publication: 15th International Conference on Algorithms and Computation
publication_identifier:
eissn:
- '16113349'
isbn:
- '9783030682101'
issn:
- '03029743'
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
record:
- id: '11938'
relation: later_version
status: public
scopus_import: '1'
status: public
title: On compatible matchings
type: conference
user_id: D865714E-FA4E-11E9-B85B-F5C5E5697425
volume: 12635
year: '2021'
...