---
_id: '8546'
abstract:
- lang: eng
  text: Brain neurons arise from relatively few progenitors generating an enormous
    diversity of neuronal types. Nonetheless, a cardinal feature of mammalian brain
    neurogenesis is thought to be that excitatory and inhibitory neurons derive from
    separate, spatially segregated progenitors. Whether bi-potential progenitors with
    an intrinsic capacity to generate both lineages exist and how such a fate decision
    may be regulated are unknown. Using cerebellar development as a model, we discover
    that individual progenitors can give rise to both inhibitory and excitatory lineages.
    Gradations of Notch activity determine the fates of the progenitors and their
    daughters. Daughters with the highest levels of Notch activity retain the progenitor
    fate, while intermediate levels of Notch activity generate inhibitory neurons,
    and daughters with very low levels of Notch signaling adopt the excitatory fate.
    Therefore, Notch-mediated binary cell fate choice is a mechanism for regulating
    the ratio of excitatory to inhibitory neurons from common progenitors.
acknowledgement: This work was supported by the program “Investissements d’avenir”
  ANR-10-IAIHU-06 , ICM , a Sorbonne Université Emergence grant, an Allen Distinguished
  Investigator Award , and the Roger De Spoelberch Foundation Prize (to B.A.H.); Armenise-Harvard
  Foundation , AIRC , and CARITRO (to L.T.); and the European Research Council under
  the European Union’s Horizon 2020 research and innovation programme grant agreement
  no. 725780 LinPro (to S.H.). T.Z. and T.L. were supported by doctoral fellowships
  from the China Scholarship Council and A.H.H. by a doctoral DOC fellowship of the
  Austrian Academy of Sciences ( 24812 ). All animal work was conducted at the PHENO-ICMice
  facility. The Core is supported by 2 “Investissements d’avenir” (ANR-10- IAIHU-06
  and ANR-11-INBS-0011-NeurATRIS) and the “Fondation pour la Recherche Médicale.”
  Light microscopy work was carried out at ICM’s imaging core facility, ICM.Quant,
  and analysis of scRNA-seq data was carried out at ICM’s bioinformatics core facility,
  iCONICS. We thank Paulina Ejsmont, Natalia Danda, and Nathalie De Geest for technical
  support. We are grateful to Dr. Shahragim TAJBAKHSH for providing R26Rstop-NICD-nGFP
  transgenic mice, Dr. Bart De Strooper for Psn1-deficient mice, Dr. Jean-Christophe
  Marine for Gt(ROSA)26SortdTom reporter mice, and Dr. Martinez Barbera for Sox2CreERT2
  mice. We also give thanks to Dr. Mikio Hoshino for providing Atoh1 and Ptf1a antibodies.
  B.A.H. is an Einstein Visiting Fellow of the Berlin Institute of Health .
article_number: '109208'
article_processing_charge: No
article_type: original
author:
- first_name: Tingting
  full_name: Zhang, Tingting
  last_name: Zhang
- first_name: Tengyuan
  full_name: Liu, Tengyuan
  last_name: Liu
- first_name: Natalia
  full_name: Mora, Natalia
  last_name: Mora
- first_name: Justine
  full_name: Guegan, Justine
  last_name: Guegan
- first_name: Mathilde
  full_name: Bertrand, Mathilde
  last_name: Bertrand
- first_name: Ximena
  full_name: Contreras, Ximena
  id: 475990FE-F248-11E8-B48F-1D18A9856A87
  last_name: Contreras
- first_name: Andi H
  full_name: Hansen, Andi H
  id: 38853E16-F248-11E8-B48F-1D18A9856A87
  last_name: Hansen
- first_name: Carmen
  full_name: Streicher, Carmen
  id: 36BCB99C-F248-11E8-B48F-1D18A9856A87
  last_name: Streicher
- first_name: Marica
  full_name: Anderle, Marica
  last_name: Anderle
- first_name: Natasha
  full_name: Danda, Natasha
  last_name: Danda
- first_name: Luca
  full_name: Tiberi, Luca
  last_name: Tiberi
- first_name: Simon
  full_name: Hippenmeyer, Simon
  id: 37B36620-F248-11E8-B48F-1D18A9856A87
  last_name: Hippenmeyer
  orcid: 0000-0003-2279-1061
- first_name: Bassem A.
  full_name: Hassan, Bassem A.
  last_name: Hassan
citation:
  ama: Zhang T, Liu T, Mora N, et al. Generation of excitatory and inhibitory neurons
    from common progenitors via Notch signaling in the cerebellum. <i>Cell Reports</i>.
    2021;35(10). doi:<a href="https://doi.org/10.1016/j.celrep.2021.109208">10.1016/j.celrep.2021.109208</a>
  apa: Zhang, T., Liu, T., Mora, N., Guegan, J., Bertrand, M., Contreras, X., … Hassan,
    B. A. (2021). Generation of excitatory and inhibitory neurons from common progenitors
    via Notch signaling in the cerebellum. <i>Cell Reports</i>. Elsevier. <a href="https://doi.org/10.1016/j.celrep.2021.109208">https://doi.org/10.1016/j.celrep.2021.109208</a>
  chicago: Zhang, Tingting, Tengyuan Liu, Natalia Mora, Justine Guegan, Mathilde Bertrand,
    Ximena Contreras, Andi H Hansen, et al. “Generation of Excitatory and Inhibitory
    Neurons from Common Progenitors via Notch Signaling in the Cerebellum.” <i>Cell
    Reports</i>. Elsevier, 2021. <a href="https://doi.org/10.1016/j.celrep.2021.109208">https://doi.org/10.1016/j.celrep.2021.109208</a>.
  ieee: T. Zhang <i>et al.</i>, “Generation of excitatory and inhibitory neurons from
    common progenitors via Notch signaling in the cerebellum,” <i>Cell Reports</i>,
    vol. 35, no. 10. Elsevier, 2021.
  ista: Zhang T, Liu T, Mora N, Guegan J, Bertrand M, Contreras X, Hansen AH, Streicher
    C, Anderle M, Danda N, Tiberi L, Hippenmeyer S, Hassan BA. 2021. Generation of
    excitatory and inhibitory neurons from common progenitors via Notch signaling
    in the cerebellum. Cell Reports. 35(10), 109208.
  mla: Zhang, Tingting, et al. “Generation of Excitatory and Inhibitory Neurons from
    Common Progenitors via Notch Signaling in the Cerebellum.” <i>Cell Reports</i>,
    vol. 35, no. 10, 109208, Elsevier, 2021, doi:<a href="https://doi.org/10.1016/j.celrep.2021.109208">10.1016/j.celrep.2021.109208</a>.
  short: T. Zhang, T. Liu, N. Mora, J. Guegan, M. Bertrand, X. Contreras, A.H. Hansen,
    C. Streicher, M. Anderle, N. Danda, L. Tiberi, S. Hippenmeyer, B.A. Hassan, Cell
    Reports 35 (2021).
date_created: 2020-09-21T12:00:48Z
date_published: 2021-06-08T00:00:00Z
date_updated: 2023-08-04T11:00:48Z
day: '08'
ddc:
- '570'
department:
- _id: SiHi
doi: 10.1016/j.celrep.2021.109208
ec_funded: 1
external_id:
  isi:
  - '000659894300001'
  pmid:
  - '34107249 '
file:
- access_level: open_access
  checksum: 7def3d42ebc8f5675efb6f38819e3e2e
  content_type: application/pdf
  creator: cziletti
  date_created: 2021-06-15T14:01:35Z
  date_updated: 2021-06-15T14:01:35Z
  file_id: '9554'
  file_name: 2021_CellReports_Zhang.pdf
  file_size: 8900385
  relation: main_file
  success: 1
file_date_updated: 2021-06-15T14:01:35Z
has_accepted_license: '1'
intvolume: '        35'
isi: 1
issue: '10'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nc-nd/4.0/
month: '06'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 260018B0-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '725780'
  name: Principles of Neural Stem Cell Lineage Progression in Cerebral Cortex Development
- _id: 2625A13E-B435-11E9-9278-68D0E5697425
  grant_number: '24812'
  name: Molecular Mechanisms of Radial Neuronal Migration
publication: Cell Reports
publication_identifier:
  eissn:
  - ' 22111247'
publication_status: published
publisher: Elsevier
quality_controlled: '1'
related_material:
  link:
  - relation: earlier_version
    url: https://doi.org/10.1101/2020.03.18.997205
scopus_import: '1'
status: public
title: Generation of excitatory and inhibitory neurons from common progenitors via
  Notch signaling in the cerebellum
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 35
year: '2021'
...
---
_id: '8582'
abstract:
- lang: eng
  text: "Cell and tissue polarization is fundamental for plant growth and morphogenesis.
    The polar, cellular localization of Arabidopsis PIN‐FORMED (PIN) proteins is crucial
    for their function in directional auxin transport. The clustering of PIN polar
    cargoes within the plasma membrane has been proposed to be important for the maintenance
    of their polar distribution. However, the more detailed features of PIN clusters
    and the cellular requirements of cargo clustering remain unclear.\r\nHere, we
    characterized PIN clusters in detail by means of multiple advanced microscopy
    and quantification methods, such as 3D quantitative imaging or freeze‐fracture
    replica labeling. The size and aggregation types of PIN clusters were determined
    by electron microscopy at the nanometer level at different polar domains and at
    different developmental stages, revealing a strong preference for clustering at
    the polar domains.\r\nPharmacological and genetic studies revealed that PIN clusters
    depend on phosphoinositol pathways, cytoskeletal structures and specific cell‐wall
    components as well as connections between the cell wall and the plasma membrane.\r\nThis
    study identifies the role of different cellular processes and structures in polar
    cargo clustering and provides initial mechanistic insight into the maintenance
    of polarity in plants and other systems."
acknowledged_ssus:
- _id: Bio
acknowledgement: We thank Dr Ingo Heilmann (Martin‐Luther‐University Halle‐Wittenberg)
  for the XVE>>PIP5K1‐YFP line, Dr Brad Day (Michigan State University) for the ndr1‐1
  mutant and the complementation lines, and Dr Patricia C. Zambryski (University of
  California, Berkeley) for the 35S::P30‐GFP line, the Bioimaging team (IST Austria)
  for assistance with imaging, group members for discussions, Martine De Cock for
  help in preparing the manuscript and Nataliia Gnyliukh for critical reading and
  revision of the manuscript. This project received funding from the European Research
  Council (ERC) under the European Union's Horizon 2020 research and innovation program
  (grant agreement No. 742985) and Comisión Nacional de Investigación Científica y
  Tecnológica (Project CONICYT‐PAI 82130047). DvW received funding from the People
  Programme (Marie Curie Actions) of the European Union’s Seventh Framework Programme
  (FP7/2007‐2013) under REA grant agreement no. 291734.
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Hongjiang
  full_name: Li, Hongjiang
  id: 33CA54A6-F248-11E8-B48F-1D18A9856A87
  last_name: Li
  orcid: 0000-0001-5039-9660
- first_name: Daniel
  full_name: von Wangenheim, Daniel
  id: 49E91952-F248-11E8-B48F-1D18A9856A87
  last_name: von Wangenheim
  orcid: 0000-0002-6862-1247
- first_name: Xixi
  full_name: Zhang, Xixi
  id: 61A66458-47E9-11EA-85BA-8AEAAF14E49A
  last_name: Zhang
  orcid: 0000-0001-7048-4627
- first_name: Shutang
  full_name: Tan, Shutang
  id: 2DE75584-F248-11E8-B48F-1D18A9856A87
  last_name: Tan
  orcid: 0000-0002-0471-8285
- first_name: Nasser
  full_name: Darwish-Miranda, Nasser
  id: 39CD9926-F248-11E8-B48F-1D18A9856A87
  last_name: Darwish-Miranda
  orcid: 0000-0002-8821-8236
- first_name: Satoshi
  full_name: Naramoto, Satoshi
  last_name: Naramoto
- first_name: Krzysztof T
  full_name: Wabnik, Krzysztof T
  id: 4DE369A4-F248-11E8-B48F-1D18A9856A87
  last_name: Wabnik
  orcid: 0000-0001-7263-0560
- first_name: Riet
  full_name: de Rycke, Riet
  last_name: de Rycke
- first_name: Walter
  full_name: Kaufmann, Walter
  id: 3F99E422-F248-11E8-B48F-1D18A9856A87
  last_name: Kaufmann
  orcid: 0000-0001-9735-5315
- first_name: Daniel J
  full_name: Gütl, Daniel J
  id: 381929CE-F248-11E8-B48F-1D18A9856A87
  last_name: Gütl
- first_name: Ricardo
  full_name: Tejos, Ricardo
  last_name: Tejos
- first_name: Peter
  full_name: Grones, Peter
  id: 399876EC-F248-11E8-B48F-1D18A9856A87
  last_name: Grones
- first_name: Meiyu
  full_name: Ke, Meiyu
  last_name: Ke
- first_name: Xu
  full_name: Chen, Xu
  id: 4E5ADCAA-F248-11E8-B48F-1D18A9856A87
  last_name: Chen
- first_name: Jan
  full_name: Dettmer, Jan
  last_name: Dettmer
- first_name: Jiří
  full_name: Friml, Jiří
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
citation:
  ama: Li H, von Wangenheim D, Zhang X, et al. Cellular requirements for PIN polar
    cargo clustering in Arabidopsis thaliana. <i>New Phytologist</i>. 2021;229(1):351-369.
    doi:<a href="https://doi.org/10.1111/nph.16887">10.1111/nph.16887</a>
  apa: Li, H., von Wangenheim, D., Zhang, X., Tan, S., Darwish-Miranda, N., Naramoto,
    S., … Friml, J. (2021). Cellular requirements for PIN polar cargo clustering in
    Arabidopsis thaliana. <i>New Phytologist</i>. Wiley. <a href="https://doi.org/10.1111/nph.16887">https://doi.org/10.1111/nph.16887</a>
  chicago: Li, Hongjiang, Daniel von Wangenheim, Xixi Zhang, Shutang Tan, Nasser Darwish-Miranda,
    Satoshi Naramoto, Krzysztof T Wabnik, et al. “Cellular Requirements for PIN Polar
    Cargo Clustering in Arabidopsis Thaliana.” <i>New Phytologist</i>. Wiley, 2021.
    <a href="https://doi.org/10.1111/nph.16887">https://doi.org/10.1111/nph.16887</a>.
  ieee: H. Li <i>et al.</i>, “Cellular requirements for PIN polar cargo clustering
    in Arabidopsis thaliana,” <i>New Phytologist</i>, vol. 229, no. 1. Wiley, pp.
    351–369, 2021.
  ista: Li H, von Wangenheim D, Zhang X, Tan S, Darwish-Miranda N, Naramoto S, Wabnik
    KT, de Rycke R, Kaufmann W, Gütl DJ, Tejos R, Grones P, Ke M, Chen X, Dettmer
    J, Friml J. 2021. Cellular requirements for PIN polar cargo clustering in Arabidopsis
    thaliana. New Phytologist. 229(1), 351–369.
  mla: Li, Hongjiang, et al. “Cellular Requirements for PIN Polar Cargo Clustering
    in Arabidopsis Thaliana.” <i>New Phytologist</i>, vol. 229, no. 1, Wiley, 2021,
    pp. 351–69, doi:<a href="https://doi.org/10.1111/nph.16887">10.1111/nph.16887</a>.
  short: H. Li, D. von Wangenheim, X. Zhang, S. Tan, N. Darwish-Miranda, S. Naramoto,
    K.T. Wabnik, R. de Rycke, W. Kaufmann, D.J. Gütl, R. Tejos, P. Grones, M. Ke,
    X. Chen, J. Dettmer, J. Friml, New Phytologist 229 (2021) 351–369.
date_created: 2020-09-28T08:59:28Z
date_published: 2021-01-01T00:00:00Z
date_updated: 2023-08-04T11:01:21Z
day: '01'
ddc:
- '580'
department:
- _id: JiFr
- _id: EM-Fac
- _id: Bio
- _id: EvBe
doi: 10.1111/nph.16887
ec_funded: 1
external_id:
  isi:
  - '000570187900001'
file:
- access_level: open_access
  checksum: b45621607b4cab97eeb1605ab58e896e
  content_type: application/pdf
  creator: dernst
  date_created: 2021-02-04T09:44:17Z
  date_updated: 2021-02-04T09:44:17Z
  file_id: '9084'
  file_name: 2021_NewPhytologist_Li.pdf
  file_size: 4061962
  relation: main_file
  success: 1
file_date_updated: 2021-02-04T09:44:17Z
has_accepted_license: '1'
intvolume: '       229'
isi: 1
issue: '1'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: 351-369
project:
- _id: 261099A6-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '742985'
  name: Tracing Evolution of Auxin Transport and Polarity in Plants
- _id: 25681D80-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '291734'
  name: International IST Postdoc Fellowship Programme
publication: New Phytologist
publication_identifier:
  eissn:
  - '14698137'
  issn:
  - 0028646X
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Cellular requirements for PIN polar cargo clustering in Arabidopsis thaliana
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 229
year: '2021'
...
---
_id: '8601'
abstract:
- lang: eng
  text: We consider large non-Hermitian real or complex random matrices X with independent,
    identically distributed centred entries. We prove that their local eigenvalue
    statistics near the spectral edge, the unit circle, coincide with those of the
    Ginibre ensemble, i.e. when the matrix elements of X are Gaussian. This result
    is the non-Hermitian counterpart of the universality of the Tracy–Widom distribution
    at the spectral edges of the Wigner ensemble.
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Giorgio
  full_name: Cipolloni, Giorgio
  id: 42198EFA-F248-11E8-B48F-1D18A9856A87
  last_name: Cipolloni
  orcid: 0000-0002-4901-7992
- first_name: László
  full_name: Erdös, László
  id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
  last_name: Erdös
  orcid: 0000-0001-5366-9603
- first_name: Dominik J
  full_name: Schröder, Dominik J
  id: 408ED176-F248-11E8-B48F-1D18A9856A87
  last_name: Schröder
  orcid: 0000-0002-2904-1856
citation:
  ama: Cipolloni G, Erdös L, Schröder DJ. Edge universality for non-Hermitian random
    matrices. <i>Probability Theory and Related Fields</i>. 2021. doi:<a href="https://doi.org/10.1007/s00440-020-01003-7">10.1007/s00440-020-01003-7</a>
  apa: Cipolloni, G., Erdös, L., &#38; Schröder, D. J. (2021). Edge universality for
    non-Hermitian random matrices. <i>Probability Theory and Related Fields</i>. Springer
    Nature. <a href="https://doi.org/10.1007/s00440-020-01003-7">https://doi.org/10.1007/s00440-020-01003-7</a>
  chicago: Cipolloni, Giorgio, László Erdös, and Dominik J Schröder. “Edge Universality
    for Non-Hermitian Random Matrices.” <i>Probability Theory and Related Fields</i>.
    Springer Nature, 2021. <a href="https://doi.org/10.1007/s00440-020-01003-7">https://doi.org/10.1007/s00440-020-01003-7</a>.
  ieee: G. Cipolloni, L. Erdös, and D. J. Schröder, “Edge universality for non-Hermitian
    random matrices,” <i>Probability Theory and Related Fields</i>. Springer Nature,
    2021.
  ista: Cipolloni G, Erdös L, Schröder DJ. 2021. Edge universality for non-Hermitian
    random matrices. Probability Theory and Related Fields.
  mla: Cipolloni, Giorgio, et al. “Edge Universality for Non-Hermitian Random Matrices.”
    <i>Probability Theory and Related Fields</i>, Springer Nature, 2021, doi:<a href="https://doi.org/10.1007/s00440-020-01003-7">10.1007/s00440-020-01003-7</a>.
  short: G. Cipolloni, L. Erdös, D.J. Schröder, Probability Theory and Related Fields
    (2021).
date_created: 2020-10-04T22:01:37Z
date_published: 2021-02-01T00:00:00Z
date_updated: 2024-03-07T15:07:53Z
day: '01'
ddc:
- '510'
department:
- _id: LaEr
doi: 10.1007/s00440-020-01003-7
ec_funded: 1
external_id:
  arxiv:
  - '1908.00969'
  isi:
  - '000572724600002'
file:
- access_level: open_access
  checksum: 611ae28d6055e1e298d53a57beb05ef4
  content_type: application/pdf
  creator: dernst
  date_created: 2020-10-05T14:53:40Z
  date_updated: 2020-10-05T14:53:40Z
  file_id: '8612'
  file_name: 2020_ProbTheory_Cipolloni.pdf
  file_size: 497032
  relation: main_file
  success: 1
file_date_updated: 2020-10-05T14:53:40Z
has_accepted_license: '1'
isi: 1
language:
- iso: eng
month: '02'
oa: 1
oa_version: Published Version
project:
- _id: B67AFEDC-15C9-11EA-A837-991A96BB2854
  name: IST Austria Open Access Fund
- _id: 258DCDE6-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '338804'
  name: Random matrices, universality and disordered quantum systems
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '665385'
  name: International IST Doctoral Program
publication: Probability Theory and Related Fields
publication_identifier:
  eissn:
  - '14322064'
  issn:
  - '01788051'
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Edge universality for non-Hermitian random matrices
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
year: '2021'
...
---
_id: '8602'
abstract:
- lang: eng
  text: Collective cell migration offers a rich field of study for non-equilibrium
    physics and cellular biology, revealing phenomena such as glassy dynamics, pattern
    formation and active turbulence. However, how mechanical and chemical signalling
    are integrated at the cellular level to give rise to such collective behaviours
    remains unclear. We address this by focusing on the highly conserved phenomenon
    of spatiotemporal waves of density and extracellular signal-regulated kinase (ERK)
    activation, which appear both in vitro and in vivo during collective cell migration
    and wound healing. First, we propose a biophysical theory, backed by mechanical
    and optogenetic perturbation experiments, showing that patterns can be quantitatively
    explained by a mechanochemical coupling between active cellular tensions and the
    mechanosensitive ERK pathway. Next, we demonstrate how this biophysical mechanism
    can robustly induce long-ranged order and migration in a desired orientation,
    and we determine the theoretically optimal wavelength and period for inducing
    maximal migration towards free edges, which fits well with experimentally observed
    dynamics. We thereby provide a bridge between the biophysical origin of spatiotemporal
    instabilities and the design principles of robust and efficient long-ranged migration.
acknowledgement: We would like to thank G. Tkacik and all of the members of the Hannezo
  and Hirashima groups for useful discussions, X. Trepat for help on traction force
  microscopy and M. Matsuda for use of the lab facility. E.H. acknowledges grants
  from the Austrian Science Fund (FWF) (P 31639) and the European Research Council
  (851288). T.H. acknowledges a grant from JST, PRESTO (JPMJPR1949). This project
  has received funding from the European Union’s Horizon 2020 research and innovation
  programme under the Marie Skłodowska-Curie grant agreement no. 665385 (to D.B.),
  from JSPS KAKENHI grant no. 17J02107 (to N.H.) and from the SPIRITS 2018 of Kyoto
  University (to E.H. and T.H.).
article_processing_charge: No
article_type: original
author:
- first_name: Daniel R
  full_name: Boocock, Daniel R
  id: 453AF628-F248-11E8-B48F-1D18A9856A87
  last_name: Boocock
  orcid: 0000-0002-1585-2631
- first_name: Naoya
  full_name: Hino, Naoya
  last_name: Hino
- first_name: Natalia
  full_name: Ruzickova, Natalia
  id: D2761128-D73D-11E9-A1BF-BA0DE6697425
  last_name: Ruzickova
- first_name: Tsuyoshi
  full_name: Hirashima, Tsuyoshi
  last_name: Hirashima
- first_name: Edouard B
  full_name: Hannezo, Edouard B
  id: 3A9DB764-F248-11E8-B48F-1D18A9856A87
  last_name: Hannezo
  orcid: 0000-0001-6005-1561
citation:
  ama: Boocock DR, Hino N, Ruzickova N, Hirashima T, Hannezo EB. Theory of mechanochemical
    patterning and optimal migration in cell monolayers. <i>Nature Physics</i>. 2021;17:267-274.
    doi:<a href="https://doi.org/10.1038/s41567-020-01037-7">10.1038/s41567-020-01037-7</a>
  apa: Boocock, D. R., Hino, N., Ruzickova, N., Hirashima, T., &#38; Hannezo, E. B.
    (2021). Theory of mechanochemical patterning and optimal migration in cell monolayers.
    <i>Nature Physics</i>. Springer Nature. <a href="https://doi.org/10.1038/s41567-020-01037-7">https://doi.org/10.1038/s41567-020-01037-7</a>
  chicago: Boocock, Daniel R, Naoya Hino, Natalia Ruzickova, Tsuyoshi Hirashima, and
    Edouard B Hannezo. “Theory of Mechanochemical Patterning and Optimal Migration
    in Cell Monolayers.” <i>Nature Physics</i>. Springer Nature, 2021. <a href="https://doi.org/10.1038/s41567-020-01037-7">https://doi.org/10.1038/s41567-020-01037-7</a>.
  ieee: D. R. Boocock, N. Hino, N. Ruzickova, T. Hirashima, and E. B. Hannezo, “Theory
    of mechanochemical patterning and optimal migration in cell monolayers,” <i>Nature
    Physics</i>, vol. 17. Springer Nature, pp. 267–274, 2021.
  ista: Boocock DR, Hino N, Ruzickova N, Hirashima T, Hannezo EB. 2021. Theory of
    mechanochemical patterning and optimal migration in cell monolayers. Nature Physics.
    17, 267–274.
  mla: Boocock, Daniel R., et al. “Theory of Mechanochemical Patterning and Optimal
    Migration in Cell Monolayers.” <i>Nature Physics</i>, vol. 17, Springer Nature,
    2021, pp. 267–74, doi:<a href="https://doi.org/10.1038/s41567-020-01037-7">10.1038/s41567-020-01037-7</a>.
  short: D.R. Boocock, N. Hino, N. Ruzickova, T. Hirashima, E.B. Hannezo, Nature Physics
    17 (2021) 267–274.
date_created: 2020-10-04T22:01:37Z
date_published: 2021-02-01T00:00:00Z
date_updated: 2023-08-04T11:02:41Z
day: '01'
department:
- _id: EdHa
doi: 10.1038/s41567-020-01037-7
ec_funded: 1
external_id:
  isi:
  - '000573519500002'
intvolume: '        17'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1101/2020.05.15.096479
month: '02'
oa: 1
oa_version: Preprint
page: 267-274
project:
- _id: 268294B6-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: P31639
  name: Active mechano-chemical description of the cell cytoskeleton
- _id: 05943252-7A3F-11EA-A408-12923DDC885E
  call_identifier: H2020
  grant_number: '851288'
  name: Design Principles of Branching Morphogenesis
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '665385'
  name: International IST Doctoral Program
publication: Nature Physics
publication_identifier:
  eissn:
  - '17452481'
  issn:
  - '17452473'
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
  link:
  - description: News on IST Homepage
    relation: press_release
    url: https://ist.ac.at/en/news/wound-healing-waves/
  record:
  - id: '12964'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: Theory of mechanochemical patterning and optimal migration in cell monolayers
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 17
year: '2021'
...
---
_id: '8603'
abstract:
- lang: eng
  text: We consider the Fröhlich polaron model in the strong coupling limit. It is
    well‐known that to leading order the ground state energy is given by the (classical)
    Pekar energy. In this work, we establish the subleading correction, describing
    quantum fluctuation about the classical limit. Our proof applies to a model of
    a confined polaron, where both the electron and the polarization field are restricted
    to a set of finite volume, with linear size determined by the natural length scale
    of the Pekar problem.
acknowledgement: Partial support through National Science Foundation GrantDMS-1363432
  (R.L.F.) and the European Research Council (ERC) under the Euro-pean Union’s Horizon
  2020 research and innovation programme (grant agreementNo 694227; R.S.), is acknowledged.
  Open access funding enabled and organizedby Projekt DEAL.
article_processing_charge: No
article_type: original
author:
- first_name: Rupert
  full_name: Frank, Rupert
  last_name: Frank
- first_name: Robert
  full_name: Seiringer, Robert
  id: 4AFD0470-F248-11E8-B48F-1D18A9856A87
  last_name: Seiringer
  orcid: 0000-0002-6781-0521
citation:
  ama: Frank R, Seiringer R. Quantum corrections to the Pekar asymptotics of a strongly
    coupled polaron. <i>Communications on Pure and Applied Mathematics</i>. 2021;74(3):544-588.
    doi:<a href="https://doi.org/10.1002/cpa.21944">10.1002/cpa.21944</a>
  apa: Frank, R., &#38; Seiringer, R. (2021). Quantum corrections to the Pekar asymptotics
    of a strongly coupled polaron. <i>Communications on Pure and Applied Mathematics</i>.
    Wiley. <a href="https://doi.org/10.1002/cpa.21944">https://doi.org/10.1002/cpa.21944</a>
  chicago: Frank, Rupert, and Robert Seiringer. “Quantum Corrections to the Pekar
    Asymptotics of a Strongly Coupled Polaron.” <i>Communications on Pure and Applied
    Mathematics</i>. Wiley, 2021. <a href="https://doi.org/10.1002/cpa.21944">https://doi.org/10.1002/cpa.21944</a>.
  ieee: R. Frank and R. Seiringer, “Quantum corrections to the Pekar asymptotics of
    a strongly coupled polaron,” <i>Communications on Pure and Applied Mathematics</i>,
    vol. 74, no. 3. Wiley, pp. 544–588, 2021.
  ista: Frank R, Seiringer R. 2021. Quantum corrections to the Pekar asymptotics of
    a strongly coupled polaron. Communications on Pure and Applied Mathematics. 74(3),
    544–588.
  mla: Frank, Rupert, and Robert Seiringer. “Quantum Corrections to the Pekar Asymptotics
    of a Strongly Coupled Polaron.” <i>Communications on Pure and Applied Mathematics</i>,
    vol. 74, no. 3, Wiley, 2021, pp. 544–88, doi:<a href="https://doi.org/10.1002/cpa.21944">10.1002/cpa.21944</a>.
  short: R. Frank, R. Seiringer, Communications on Pure and Applied Mathematics 74
    (2021) 544–588.
date_created: 2020-10-04T22:01:37Z
date_published: 2021-03-01T00:00:00Z
date_updated: 2023-08-04T11:02:16Z
day: '01'
ddc:
- '510'
department:
- _id: RoSe
doi: 10.1002/cpa.21944
ec_funded: 1
external_id:
  isi:
  - '000572991500001'
file:
- access_level: open_access
  checksum: 5f665ffa6e6dd958aec5c3040cbcfa84
  content_type: application/pdf
  creator: dernst
  date_created: 2021-03-11T10:03:30Z
  date_updated: 2021-03-11T10:03:30Z
  file_id: '9236'
  file_name: 2021_CommPureApplMath_Frank.pdf
  file_size: 334987
  relation: main_file
  success: 1
file_date_updated: 2021-03-11T10:03:30Z
has_accepted_license: '1'
intvolume: '        74'
isi: 1
issue: '3'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
page: 544-588
project:
- _id: 25C6DC12-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '694227'
  name: Analysis of quantum many-body systems
publication: Communications on Pure and Applied Mathematics
publication_identifier:
  eissn:
  - '10970312'
  issn:
  - '00103640'
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Quantum corrections to the Pekar asymptotics of a strongly coupled polaron
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 74
year: '2021'
...
---
_id: '8606'
abstract:
- lang: eng
  text: The leaf is a crucial organ evolved with remarkable morphological diversity
    to maximize plant photosynthesis. The leaf shape is a key trait that affects photosynthesis,
    flowering rates, disease resistance, and yield. Although many genes regulating
    leaf development have been identified in the past years, the precise regulatory
    architecture underlying the generation of diverse leaf shapes remains to be elucidated.
    We used cotton as a reference model to probe the genetic framework underlying
    divergent leaf forms. Comparative transcriptome analysis revealed that the GhARF16‐1
    and GhKNOX2‐1 genes might be potential regulators of leaf shape. We functionally
    characterized the auxin‐responsive factor ARF16‐1 acting upstream of GhKNOX2‐1
    to determine leaf morphology in cotton. The transcription of GhARF16‐1 was significantly
    higher in lobed‐leaved cotton than in smooth‐leaved cotton. Furthermore, the overexpression
    of GhARF16‐1 led to the upregulation of GhKNOX2‐1 and resulted in more and deeper
    serrations in cotton leaves, similar to the leaf shape of cotton plants overexpressing
    GhKNOX2‐1. We found that GhARF16‐1 specifically bound to the promoter of GhKNOX2‐1
    to induce its expression. The heterologous expression of GhARF16‐1 and GhKNOX2‐1
    in Arabidopsis led to lobed and curly leaves, and a genetic analysis revealed
    that GhKNOX2‐1 is epistatic to GhARF16‐1 in Arabidopsis, suggesting that the GhARF16‐1
    and GhKNOX2‐1 interaction paradigm also functions to regulate leaf shape in Arabidopsis.
    To our knowledge, our results uncover a novel mechanism by which auxin, through
    the key component ARF16‐1 and its downstream‐activated gene KNOX2‐1, determines
    leaf morphology in eudicots.
acknowledgement: We are thankful to Professor Yuxian Zhu from Wuhan University for
  his extremely valuable remarks and helpful comments on the manuscript. This work
  was supported by the Shaanxi Natural Science Foundation (2019JQ‐062 and 2020JQ‐410),
  Shaanxi Youth Entrusted Talents Program (20190205), China Postdoctoral Science Foundation
  (2018M640947, 2020T130394), Shaanxi Postdoctoral Project (2018BSHYDZZ76), Natural
  Science Basic Research Plan in Shaanxi Province of China (2018JZ3006), Fundamental
  Research Funds for the Central Universities (GK201903064, GK201901004, GK202002005
  and GK202001004), and State Key Laboratory of Cotton Biology Open Fund (CB2020A12).
article_processing_charge: No
article_type: original
author:
- first_name: P
  full_name: He, P
  last_name: He
- first_name: Yuzhou
  full_name: Zhang, Yuzhou
  id: 3B6137F2-F248-11E8-B48F-1D18A9856A87
  last_name: Zhang
  orcid: 0000-0003-2627-6956
- first_name: H
  full_name: Li, H
  last_name: Li
- first_name: X
  full_name: Fu, X
  last_name: Fu
- first_name: H
  full_name: Shang, H
  last_name: Shang
- first_name: C
  full_name: Zou, C
  last_name: Zou
- first_name: Jiří
  full_name: Friml, Jiří
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
- first_name: G
  full_name: Xiao, G
  last_name: Xiao
citation:
  ama: He P, Zhang Y, Li H, et al. GhARF16-1 modulates leaf development by transcriptionally
    regulating the GhKNOX2-1 gene in cotton. <i>Plant Biotechnology Journal</i>. 2021;19(3):548-562.
    doi:<a href="https://doi.org/10.1111/pbi.13484">10.1111/pbi.13484</a>
  apa: He, P., Zhang, Y., Li, H., Fu, X., Shang, H., Zou, C., … Xiao, G. (2021). GhARF16-1
    modulates leaf development by transcriptionally regulating the GhKNOX2-1 gene
    in cotton. <i>Plant Biotechnology Journal</i>. Wiley. <a href="https://doi.org/10.1111/pbi.13484">https://doi.org/10.1111/pbi.13484</a>
  chicago: He, P, Yuzhou Zhang, H Li, X Fu, H Shang, C Zou, Jiří Friml, and G Xiao.
    “GhARF16-1 Modulates Leaf Development by Transcriptionally Regulating the GhKNOX2-1
    Gene in Cotton.” <i>Plant Biotechnology Journal</i>. Wiley, 2021. <a href="https://doi.org/10.1111/pbi.13484">https://doi.org/10.1111/pbi.13484</a>.
  ieee: P. He <i>et al.</i>, “GhARF16-1 modulates leaf development by transcriptionally
    regulating the GhKNOX2-1 gene in cotton,” <i>Plant Biotechnology Journal</i>,
    vol. 19, no. 3. Wiley, pp. 548–562, 2021.
  ista: He P, Zhang Y, Li H, Fu X, Shang H, Zou C, Friml J, Xiao G. 2021. GhARF16-1
    modulates leaf development by transcriptionally regulating the GhKNOX2-1 gene
    in cotton. Plant Biotechnology Journal. 19(3), 548–562.
  mla: He, P., et al. “GhARF16-1 Modulates Leaf Development by Transcriptionally Regulating
    the GhKNOX2-1 Gene in Cotton.” <i>Plant Biotechnology Journal</i>, vol. 19, no.
    3, Wiley, 2021, pp. 548–62, doi:<a href="https://doi.org/10.1111/pbi.13484">10.1111/pbi.13484</a>.
  short: P. He, Y. Zhang, H. Li, X. Fu, H. Shang, C. Zou, J. Friml, G. Xiao, Plant
    Biotechnology Journal 19 (2021) 548–562.
date_created: 2020-10-05T12:44:33Z
date_published: 2021-03-01T00:00:00Z
date_updated: 2023-08-04T11:03:10Z
day: '01'
ddc:
- '580'
department:
- _id: JiFr
doi: 10.1111/pbi.13484
external_id:
  isi:
  - '000577682300001'
  pmid:
  - '32981232'
file:
- access_level: open_access
  checksum: 63845be37fb962586e0c7773f2355970
  content_type: application/pdf
  creator: dernst
  date_created: 2021-04-12T12:29:07Z
  date_updated: 2021-04-12T12:29:07Z
  file_id: '9321'
  file_name: 2021_PlantBiotechJournal_He.pdf
  file_size: 15691871
  relation: main_file
  success: 1
file_date_updated: 2021-04-12T12:29:07Z
has_accepted_license: '1'
intvolume: '        19'
isi: 1
issue: '3'
language:
- iso: eng
month: '03'
oa: 1
oa_version: Published Version
page: 548-562
pmid: 1
publication: Plant Biotechnology Journal
publication_identifier:
  issn:
  - 1467-7644
  - 1467-7652
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: GhARF16-1 modulates leaf development by transcriptionally regulating the GhKNOX2-1
  gene in cotton
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 19
year: '2021'
...
---
_id: '8608'
abstract:
- lang: eng
  text: To adapt to the diverse array of biotic and abiotic cues, plants have evolved
    sophisticated mechanisms to sense changes in environmental conditions and modulate
    their growth. Growth-promoting hormones and defence signalling fine tune plant
    development antagonistically. During host-pathogen interactions, this defence-growth
    trade-off is mediated by the counteractive effects of the defence hormone salicylic
    acid (SA) and the growth hormone auxin. Here we revealed an underlying mechanism
    of SA regulating auxin signalling by constraining the plasma membrane dynamics
    of PIN2 auxin efflux transporter in Arabidopsis thaliana roots. The lateral diffusion
    of PIN2 proteins is constrained by SA signalling, during which PIN2 proteins are
    condensed into hyperclusters depending on REM1.2-mediated nanodomain compartmentalisation.
    Furthermore, membrane nanodomain compartmentalisation by SA or Remorin (REM) assembly
    significantly suppressed clathrin-mediated endocytosis. Consequently, SA-induced
    heterogeneous surface condensation disrupted asymmetric auxin distribution and
    the resultant gravitropic response. Our results demonstrated a defence-growth
    trade-off mechanism by which SA signalling crosstalked with auxin transport by
    concentrating membrane-resident PIN2 into heterogeneous compartments.
acknowledgement: This work was supported by the National Key Research andDevelopment
  Programme of China (2017YFA0506100), theNational Natural Science Foundation of China
  (31870170 and31701168), and the Fok Ying Tung Education Foundation(161027) to XC;
  NTU startup grant (M4081533) and NIM/01/2016 (NTU, Singapore) to YM. We thank Lei
  Shi andZhongquan Lin for microscopy assistance.
article_processing_charge: No
article_type: original
author:
- first_name: M
  full_name: Ke, M
  last_name: Ke
- first_name: Z
  full_name: Ma, Z
  last_name: Ma
- first_name: D
  full_name: Wang, D
  last_name: Wang
- first_name: Y
  full_name: Sun, Y
  last_name: Sun
- first_name: C
  full_name: Wen, C
  last_name: Wen
- first_name: D
  full_name: Huang, D
  last_name: Huang
- first_name: Z
  full_name: Chen, Z
  last_name: Chen
- first_name: L
  full_name: Yang, L
  last_name: Yang
- first_name: Shutang
  full_name: Tan, Shutang
  id: 2DE75584-F248-11E8-B48F-1D18A9856A87
  last_name: Tan
  orcid: 0000-0002-0471-8285
- first_name: R
  full_name: Li, R
  last_name: Li
- first_name: Jiří
  full_name: Friml, Jiří
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
- first_name: Y
  full_name: Miao, Y
  last_name: Miao
- first_name: X
  full_name: Chen, X
  last_name: Chen
citation:
  ama: Ke M, Ma Z, Wang D, et al. Salicylic acid regulates PIN2 auxin transporter
    hyper-clustering and root gravitropic growth via Remorin-dependent lipid nanodomain
    organization in Arabidopsis thaliana. <i>New Phytologist</i>. 2021;229(2):963-978.
    doi:<a href="https://doi.org/10.1111/nph.16915">10.1111/nph.16915</a>
  apa: Ke, M., Ma, Z., Wang, D., Sun, Y., Wen, C., Huang, D., … Chen, X. (2021). Salicylic
    acid regulates PIN2 auxin transporter hyper-clustering and root gravitropic growth
    via Remorin-dependent lipid nanodomain organization in Arabidopsis thaliana. <i>New
    Phytologist</i>. Wiley. <a href="https://doi.org/10.1111/nph.16915">https://doi.org/10.1111/nph.16915</a>
  chicago: Ke, M, Z Ma, D Wang, Y Sun, C Wen, D Huang, Z Chen, et al. “Salicylic Acid
    Regulates PIN2 Auxin Transporter Hyper-Clustering and Root Gravitropic Growth
    via Remorin-Dependent Lipid Nanodomain Organization in Arabidopsis Thaliana.”
    <i>New Phytologist</i>. Wiley, 2021. <a href="https://doi.org/10.1111/nph.16915">https://doi.org/10.1111/nph.16915</a>.
  ieee: M. Ke <i>et al.</i>, “Salicylic acid regulates PIN2 auxin transporter hyper-clustering
    and root gravitropic growth via Remorin-dependent lipid nanodomain organization
    in Arabidopsis thaliana,” <i>New Phytologist</i>, vol. 229, no. 2. Wiley, pp.
    963–978, 2021.
  ista: Ke M, Ma Z, Wang D, Sun Y, Wen C, Huang D, Chen Z, Yang L, Tan S, Li R, Friml
    J, Miao Y, Chen X. 2021. Salicylic acid regulates PIN2 auxin transporter hyper-clustering
    and root gravitropic growth via Remorin-dependent lipid nanodomain organization
    in Arabidopsis thaliana. New Phytologist. 229(2), 963–978.
  mla: Ke, M., et al. “Salicylic Acid Regulates PIN2 Auxin Transporter Hyper-Clustering
    and Root Gravitropic Growth via Remorin-Dependent Lipid Nanodomain Organization
    in Arabidopsis Thaliana.” <i>New Phytologist</i>, vol. 229, no. 2, Wiley, 2021,
    pp. 963–78, doi:<a href="https://doi.org/10.1111/nph.16915">10.1111/nph.16915</a>.
  short: M. Ke, Z. Ma, D. Wang, Y. Sun, C. Wen, D. Huang, Z. Chen, L. Yang, S. Tan,
    R. Li, J. Friml, Y. Miao, X. Chen, New Phytologist 229 (2021) 963–978.
date_created: 2020-10-05T12:45:36Z
date_published: 2021-01-01T00:00:00Z
date_updated: 2023-09-05T16:06:24Z
day: '01'
ddc:
- '580'
department:
- _id: JiFr
doi: 10.1111/nph.16915
external_id:
  isi:
  - '000573568000001'
  pmid:
  - '32901934'
file:
- access_level: open_access
  checksum: d36b6a8c6fafab66264e0d27114dae63
  content_type: application/pdf
  creator: dernst
  date_created: 2021-02-04T09:53:16Z
  date_updated: 2021-02-04T09:53:16Z
  file_id: '9085'
  file_name: 2021_NewPhytologist_Ke.pdf
  file_size: 3674502
  relation: main_file
  success: 1
file_date_updated: 2021-02-04T09:53:16Z
has_accepted_license: '1'
intvolume: '       229'
isi: 1
issue: '2'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: 963-978
pmid: 1
publication: New Phytologist
publication_identifier:
  eissn:
  - 1469-8137
  issn:
  - 0028-646x
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Salicylic acid regulates PIN2 auxin transporter hyper-clustering and root gravitropic
  growth via Remorin-dependent lipid nanodomain organization in Arabidopsis thaliana
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: c635000d-4b10-11ee-a964-aac5a93f6ac1
volume: 229
year: '2021'
...
---
_id: '8673'
abstract:
- lang: eng
  text: In RuCl3, inelastic neutron scattering and Raman spectroscopy reveal a continuum
    of non-spin-wave excitations that persists to high temperature, suggesting the
    presence of a spin liquid state on a honeycomb lattice. In the context of the
    Kitaev model, finite magnetic fields introduce interactions between the elementary
    excitations, and thus the effects of high magnetic fields that are comparable
    to the spin-exchange energy scale must be explored. Here, we report measurements
    of the magnetotropic coefficient—the thermodynamic coefficient associated with
    magnetic anisotropy—over a wide range of magnetic fields and temperatures. We
    find that magnetic field and temperature compete to determine the magnetic response
    in a way that is independent of the large intrinsic exchange-interaction energy.
    This emergent scale-invariant magnetic anisotropy provides evidence for a high
    degree of exchange frustration that favours the formation of a spin liquid state
    in RuCl3.
acknowledgement: We thank M. Baenitz, A. Bangura, R. Coldea, G. Jackeli, S. Kivelson,
  S. Nagler, R. Valenti, C. Varma, S. Winter and J. Zaanen for insightful discussions.
  Samples were grown at the Max Planck Institute for Chemical Physics of Solids. The
  d.c.-field measurements were made at the National High Magnetic Field Laboratory
  (NHMFL) in Tallahassee, FL. The pulsed-field measurements were made in the Pulsed
  Field Facility of the NHMFL in Los Alamos, NM. All work at the NHMFL is supported
  through the National Science Foundation Cooperative Agreement nos. DMR-1157490 and
  DMR-1644779, the US Department of Energy and the State of Florida. R.D.M. acknowledges
  support from LANL LDRD-DR 20160085 Topology and Strong Correlations. M.C. acknowledges
  support from the Department of Energy ‘Science of 100 tesla’ BES programme for high-field
  experiments. X-ray data acquisition and analysis was performed at Cornell University.
  Research conducted at the Cornell High Energy Synchrotron Source (CHESS) is supported
  by the National Science Foundation under award no. DMR-1332208. B.J.R. acknowledges
  support from the Institute for Quantum Matter, an Energy Frontier Research Center
  funded by the US Department of Energy, Office of Science, Office of Basic Energy
  Sciences under award no. DE-SC0019331. Y.L. acknowledges support from the US Department
  of Energy through the LANL/LDRD programme and the G.T. Seaborg institute. J.C.P.
  is supported by a Gabilan Stanford Graduate Fellowship and an NSF Graduate Research
  Fellowship (grant no. DGE-114747). P.J.W.M. acknowledges funding from the Swiss
  National Science Foundation through project no. PP00P2-176789.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Kimberly A
  full_name: Modic, Kimberly A
  id: 13C26AC0-EB69-11E9-87C6-5F3BE6697425
  last_name: Modic
  orcid: 0000-0001-9760-3147
- first_name: Ross D.
  full_name: McDonald, Ross D.
  last_name: McDonald
- first_name: J.P.C.
  full_name: Ruff, J.P.C.
  last_name: Ruff
- first_name: Maja D.
  full_name: Bachmann, Maja D.
  last_name: Bachmann
- first_name: You
  full_name: Lai, You
  last_name: Lai
- first_name: Johanna C.
  full_name: Palmstrom, Johanna C.
  last_name: Palmstrom
- first_name: David
  full_name: Graf, David
  last_name: Graf
- first_name: Mun K.
  full_name: Chan, Mun K.
  last_name: Chan
- first_name: F.F.
  full_name: Balakirev, F.F.
  last_name: Balakirev
- first_name: J.B.
  full_name: Betts, J.B.
  last_name: Betts
- first_name: G.S.
  full_name: Boebinger, G.S.
  last_name: Boebinger
- first_name: Marcus
  full_name: Schmidt, Marcus
  last_name: Schmidt
- first_name: Michael J.
  full_name: Lawler, Michael J.
  last_name: Lawler
- first_name: D.A.
  full_name: Sokolov, D.A.
  last_name: Sokolov
- first_name: Philip J.W.
  full_name: Moll, Philip J.W.
  last_name: Moll
- first_name: B.J.
  full_name: Ramshaw, B.J.
  last_name: Ramshaw
- first_name: Arkady
  full_name: Shekhter, Arkady
  last_name: Shekhter
citation:
  ama: Modic KA, McDonald RD, Ruff JPC, et al. Scale-invariant magnetic anisotropy
    in RuCl3 at high magnetic fields. <i>Nature Physics</i>. 2021;17:240-244. doi:<a
    href="https://doi.org/10.1038/s41567-020-1028-0">10.1038/s41567-020-1028-0</a>
  apa: Modic, K. A., McDonald, R. D., Ruff, J. P. C., Bachmann, M. D., Lai, Y., Palmstrom,
    J. C., … Shekhter, A. (2021). Scale-invariant magnetic anisotropy in RuCl3 at
    high magnetic fields. <i>Nature Physics</i>. Springer Nature. <a href="https://doi.org/10.1038/s41567-020-1028-0">https://doi.org/10.1038/s41567-020-1028-0</a>
  chicago: Modic, Kimberly A, Ross D. McDonald, J.P.C. Ruff, Maja D. Bachmann, You
    Lai, Johanna C. Palmstrom, David Graf, et al. “Scale-Invariant Magnetic Anisotropy
    in RuCl3 at High Magnetic Fields.” <i>Nature Physics</i>. Springer Nature, 2021.
    <a href="https://doi.org/10.1038/s41567-020-1028-0">https://doi.org/10.1038/s41567-020-1028-0</a>.
  ieee: K. A. Modic <i>et al.</i>, “Scale-invariant magnetic anisotropy in RuCl3 at
    high magnetic fields,” <i>Nature Physics</i>, vol. 17. Springer Nature, pp. 240–244,
    2021.
  ista: Modic KA, McDonald RD, Ruff JPC, Bachmann MD, Lai Y, Palmstrom JC, Graf D,
    Chan MK, Balakirev FF, Betts JB, Boebinger GS, Schmidt M, Lawler MJ, Sokolov DA,
    Moll PJW, Ramshaw BJ, Shekhter A. 2021. Scale-invariant magnetic anisotropy in
    RuCl3 at high magnetic fields. Nature Physics. 17, 240–244.
  mla: Modic, Kimberly A., et al. “Scale-Invariant Magnetic Anisotropy in RuCl3 at
    High Magnetic Fields.” <i>Nature Physics</i>, vol. 17, Springer Nature, 2021,
    pp. 240–44, doi:<a href="https://doi.org/10.1038/s41567-020-1028-0">10.1038/s41567-020-1028-0</a>.
  short: K.A. Modic, R.D. McDonald, J.P.C. Ruff, M.D. Bachmann, Y. Lai, J.C. Palmstrom,
    D. Graf, M.K. Chan, F.F. Balakirev, J.B. Betts, G.S. Boebinger, M. Schmidt, M.J.
    Lawler, D.A. Sokolov, P.J.W. Moll, B.J. Ramshaw, A. Shekhter, Nature Physics 17
    (2021) 240–244.
date_created: 2020-10-18T22:01:37Z
date_published: 2021-02-01T00:00:00Z
date_updated: 2023-08-04T11:03:39Z
day: '01'
department:
- _id: KiMo
doi: 10.1038/s41567-020-1028-0
external_id:
  arxiv:
  - '2005.04228'
  isi:
  - '000575344700003'
intvolume: '        17'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/2005.04228
month: '02'
oa: 1
oa_version: Preprint
page: 240-244
publication: Nature Physics
publication_identifier:
  eissn:
  - '17452481'
  issn:
  - '17452473'
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Scale-invariant magnetic anisotropy in RuCl3 at high magnetic fields
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 17
year: '2021'
...
---
_id: '8689'
abstract:
- lang: eng
  text: 'This paper continues the discussion started in [CK19] concerning Arnold''s
    legacy on classical KAM theory and (some of) its modern developments. We prove
    a detailed and explicit `global'' Arnold''s KAM Theorem, which yields, in particular,
    the Whitney conjugacy of a non{degenerate, real{analytic, nearly-integrable Hamiltonian
    system to an integrable system on a closed, nowhere dense, positive measure subset
    of the phase space. Detailed measure estimates on the Kolmogorov''s set are provided
    in the case the phase space is: (A) a uniform neighbourhood of an arbitrary (bounded)
    set times the d-torus and (B) a domain with C2 boundary times the d-torus. All
    constants are explicitly given.'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Luigi
  full_name: Chierchia, Luigi
  last_name: Chierchia
- first_name: Edmond
  full_name: Koudjinan, Edmond
  id: 52DF3E68-AEFA-11EA-95A4-124A3DDC885E
  last_name: Koudjinan
  orcid: 0000-0003-2640-4049
citation:
  ama: Chierchia L, Koudjinan E. V.I. Arnold’s “‘Global’” KAM theorem and geometric
    measure estimates. <i>Regular and Chaotic Dynamics</i>. 2021;26(1):61-88. doi:<a
    href="https://doi.org/10.1134/S1560354721010044">10.1134/S1560354721010044</a>
  apa: Chierchia, L., &#38; Koudjinan, E. (2021). V.I. Arnold’s “‘Global’” KAM theorem
    and geometric measure estimates. <i>Regular and Chaotic Dynamics</i>. Springer
    Nature. <a href="https://doi.org/10.1134/S1560354721010044">https://doi.org/10.1134/S1560354721010044</a>
  chicago: Chierchia, Luigi, and Edmond Koudjinan. “V.I. Arnold’s ‘“Global”’ KAM Theorem
    and Geometric Measure Estimates.” <i>Regular and Chaotic Dynamics</i>. Springer
    Nature, 2021. <a href="https://doi.org/10.1134/S1560354721010044">https://doi.org/10.1134/S1560354721010044</a>.
  ieee: L. Chierchia and E. Koudjinan, “V.I. Arnold’s ‘“Global”’ KAM theorem and geometric
    measure estimates,” <i>Regular and Chaotic Dynamics</i>, vol. 26, no. 1. Springer
    Nature, pp. 61–88, 2021.
  ista: Chierchia L, Koudjinan E. 2021. V.I. Arnold’s ‘“Global”’ KAM theorem and geometric
    measure estimates. Regular and Chaotic Dynamics. 26(1), 61–88.
  mla: Chierchia, Luigi, and Edmond Koudjinan. “V.I. Arnold’s ‘“Global”’ KAM Theorem
    and Geometric Measure Estimates.” <i>Regular and Chaotic Dynamics</i>, vol. 26,
    no. 1, Springer Nature, 2021, pp. 61–88, doi:<a href="https://doi.org/10.1134/S1560354721010044">10.1134/S1560354721010044</a>.
  short: L. Chierchia, E. Koudjinan, Regular and Chaotic Dynamics 26 (2021) 61–88.
date_created: 2020-10-21T14:56:47Z
date_published: 2021-02-03T00:00:00Z
date_updated: 2023-08-07T13:37:27Z
day: '03'
ddc:
- '515'
department:
- _id: VaKa
doi: 10.1134/S1560354721010044
external_id:
  arxiv:
  - '2010.13243'
  isi:
  - '000614454700004'
intvolume: '        26'
isi: 1
issue: '1'
keyword:
- Nearly{integrable Hamiltonian systems
- perturbation theory
- KAM Theory
- Arnold's scheme
- Kolmogorov's set
- primary invariant tori
- Lagrangian tori
- measure estimates
- small divisors
- integrability on nowhere dense sets
- Diophantine frequencies.
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/2010.13243
month: '02'
oa: 1
oa_version: Preprint
page: 61-88
publication: Regular and Chaotic Dynamics
publication_identifier:
  issn:
  - 1560-3547
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: V.I. Arnold's ''Global'' KAM theorem and geometric measure estimates
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 26
year: '2021'
...
---
_id: '8708'
abstract:
- lang: eng
  text: The Mytilus complex of marine mussel species forms a mosaic of hybrid zones,
    found across temperate regions of the globe. This allows us to study ‘replicated’
    instances of secondary contact between closely related species. Previous work
    on this complex has shown that local introgression is both widespread and highly
    heterogeneous, and has identified SNPs that are outliers of differentiation between
    lineages. Here, we developed an ancestry‐informative panel of such SNPs. We then
    compared their frequencies in newly sampled populations, including samples from
    within the hybrid zones, and parental populations at different distances from
    the contact. Results show that close to the hybrid zones, some outlier loci are
    near to fixation for the heterospecific allele, suggesting enhanced local introgression,
    or the local sweep of a shared ancestral allele. Conversely, genomic cline analyses,
    treating local parental populations as the reference, reveal a globally high concordance
    among loci, albeit with a few signals of asymmetric introgression. Enhanced local
    introgression at specific loci is consistent with the early transfer of adaptive
    variants after contact, possibly including asymmetric bi‐stable variants (Dobzhansky‐Muller
    incompatibilities), or haplotypes loaded with fewer deleterious mutations. Having
    escaped one barrier, however, these variants can be trapped or delayed at the
    next barrier, confining the introgression locally. These results shed light on
    the decay of species barriers during phases of contact.
acknowledgement: Data used in this work were partly produced through the genotyping
  and sequencing facilities of ISEM and LabEx CeMEB, an ANR ‘Investissements d'avenir’
  program (ANR‐10‐LABX‐04‐01) This project benefited from the Montpellier Bioinformatics
  Biodiversity platform supported by the LabEx CeMEB. We thank Norah Saarman, Grant
  Pogson, Célia Gosset and Pierre‐Alexandre Gagnaire for providing samples. This work
  was funded by a Languedoc‐Roussillon ‘Chercheur(se)s d'Avenir’ grant (Connect7 project).
  P. Strelkov was supported by the Russian Science Foundation project 19‐74‐20024.
  This is article 2020‐240 of Institut des Sciences de l'Evolution de Montpellier.
article_processing_charge: No
article_type: original
author:
- first_name: Alexis
  full_name: Simon, Alexis
  last_name: Simon
- first_name: Christelle
  full_name: Fraisse, Christelle
  id: 32DF5794-F248-11E8-B48F-1D18A9856A87
  last_name: Fraisse
  orcid: 0000-0001-8441-5075
- first_name: Tahani
  full_name: El Ayari, Tahani
  last_name: El Ayari
- first_name: Cathy
  full_name: Liautard‐Haag, Cathy
  last_name: Liautard‐Haag
- first_name: Petr
  full_name: Strelkov, Petr
  last_name: Strelkov
- first_name: John J
  full_name: Welch, John J
  last_name: Welch
- first_name: Nicolas
  full_name: Bierne, Nicolas
  last_name: Bierne
citation:
  ama: Simon A, Fraisse C, El Ayari T, et al. How do species barriers decay? Concordance
    and local introgression in mosaic hybrid zones of mussels. <i>Journal of Evolutionary
    Biology</i>. 2021;34(1):208-223. doi:<a href="https://doi.org/10.1111/jeb.13709">10.1111/jeb.13709</a>
  apa: Simon, A., Fraisse, C., El Ayari, T., Liautard‐Haag, C., Strelkov, P., Welch,
    J. J., &#38; Bierne, N. (2021). How do species barriers decay? Concordance and
    local introgression in mosaic hybrid zones of mussels. <i>Journal of Evolutionary
    Biology</i>. Wiley. <a href="https://doi.org/10.1111/jeb.13709">https://doi.org/10.1111/jeb.13709</a>
  chicago: Simon, Alexis, Christelle Fraisse, Tahani El Ayari, Cathy Liautard‐Haag,
    Petr Strelkov, John J Welch, and Nicolas Bierne. “How Do Species Barriers Decay?
    Concordance and Local Introgression in Mosaic Hybrid Zones of Mussels.” <i>Journal
    of Evolutionary Biology</i>. Wiley, 2021. <a href="https://doi.org/10.1111/jeb.13709">https://doi.org/10.1111/jeb.13709</a>.
  ieee: A. Simon <i>et al.</i>, “How do species barriers decay? Concordance and local
    introgression in mosaic hybrid zones of mussels,” <i>Journal of Evolutionary Biology</i>,
    vol. 34, no. 1. Wiley, pp. 208–223, 2021.
  ista: Simon A, Fraisse C, El Ayari T, Liautard‐Haag C, Strelkov P, Welch JJ, Bierne
    N. 2021. How do species barriers decay? Concordance and local introgression in
    mosaic hybrid zones of mussels. Journal of Evolutionary Biology. 34(1), 208–223.
  mla: Simon, Alexis, et al. “How Do Species Barriers Decay? Concordance and Local
    Introgression in Mosaic Hybrid Zones of Mussels.” <i>Journal of Evolutionary Biology</i>,
    vol. 34, no. 1, Wiley, 2021, pp. 208–23, doi:<a href="https://doi.org/10.1111/jeb.13709">10.1111/jeb.13709</a>.
  short: A. Simon, C. Fraisse, T. El Ayari, C. Liautard‐Haag, P. Strelkov, J.J. Welch,
    N. Bierne, Journal of Evolutionary Biology 34 (2021) 208–223.
date_created: 2020-10-25T23:01:20Z
date_published: 2021-01-01T00:00:00Z
date_updated: 2023-08-04T11:04:11Z
day: '01'
department:
- _id: BeVi
- _id: NiBa
doi: 10.1111/jeb.13709
external_id:
  isi:
  - '000579599700001'
  pmid:
  - '33045123'
intvolume: '        34'
isi: 1
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1101/818559
month: '01'
oa: 1
oa_version: Preprint
page: 208-223
pmid: 1
publication: Journal of Evolutionary Biology
publication_identifier:
  eissn:
  - '14209101'
  issn:
  - 1010061X
publication_status: published
publisher: Wiley
quality_controlled: '1'
related_material:
  record:
  - id: '13073'
    relation: research_data
    status: public
scopus_import: '1'
status: public
title: How do species barriers decay? Concordance and local introgression in mosaic
  hybrid zones of mussels
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 34
year: '2021'
...
---
_id: '8723'
abstract:
- lang: eng
  text: Deep learning at scale is dominated by communication time. Distributing samples
    across nodes usually yields the best performance, but poses scaling challenges
    due to global information dissemination and load imbalance across uneven sample
    lengths. State-of-the-art decentralized optimizers mitigate the problem, but require
    more iterations to achieve the same accuracy as their globally-communicating counterparts.
    We present Wait-Avoiding Group Model Averaging (WAGMA) SGD, a wait-avoiding stochastic
    optimizer that reduces global communication via subgroup weight exchange. The
    key insight is a combination of algorithmic changes to the averaging scheme and
    the use of a group allreduce operation. We prove the convergence of WAGMA-SGD,
    and empirically show that it retains convergence rates similar to Allreduce-SGD.
    For evaluation, we train ResNet-50 on ImageNet; Transformer for machine translation;
    and deep reinforcement learning for navigation at scale. Compared with state-of-the-art
    decentralized SGD variants, WAGMA-SGD significantly improves training throughput
    (e.g., 2.1× on 1,024 GPUs for reinforcement learning), and achieves the fastest
    time-to-solution (e.g., the highest score using the shortest training time for
    Transformer).
acknowledgement: "This project has received funding from the European Research Council
  (ERC) under the European Union’s Hori-\r\nzon 2020 programme under Grant DAPP, Grant
  678880; EPi-GRAM-HS, Grant 801039; and ERC Starting Grant ScaleML, Grant 805223.
  The work of Tal Ben-Nun is supported by the Swiss National Science Foundation (Ambizione
  Project No. 185778). The work of Nikoli Dryden is supported by the ETH Postdoctoral
  Fellowship. The authors would like to thank the Swiss National Supercomputing Center
  for providing the computing resources and technical support."
article_number: '9271898'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Shigang
  full_name: Li, Shigang
  last_name: Li
- first_name: Tal Ben-Nun
  full_name: Tal Ben-Nun, Tal Ben-Nun
  last_name: Tal Ben-Nun
- first_name: Giorgi
  full_name: Nadiradze, Giorgi
  id: 3279A00C-F248-11E8-B48F-1D18A9856A87
  last_name: Nadiradze
- first_name: Salvatore Di
  full_name: Girolamo, Salvatore Di
  last_name: Girolamo
- first_name: Nikoli
  full_name: Dryden, Nikoli
  last_name: Dryden
- first_name: Dan-Adrian
  full_name: Alistarh, Dan-Adrian
  id: 4A899BFC-F248-11E8-B48F-1D18A9856A87
  last_name: Alistarh
  orcid: 0000-0003-3650-940X
- first_name: Torsten
  full_name: Hoefler, Torsten
  last_name: Hoefler
citation:
  ama: Li S, Tal Ben-Nun TB-N, Nadiradze G, et al. Breaking (global) barriers in parallel
    stochastic optimization with wait-avoiding group averaging. <i>IEEE Transactions
    on Parallel and Distributed Systems</i>. 2021;32(7). doi:<a href="https://doi.org/10.1109/TPDS.2020.3040606">10.1109/TPDS.2020.3040606</a>
  apa: Li, S., Tal Ben-Nun, T. B.-N., Nadiradze, G., Girolamo, S. D., Dryden, N.,
    Alistarh, D.-A., &#38; Hoefler, T. (2021). Breaking (global) barriers in parallel
    stochastic optimization with wait-avoiding group averaging. <i>IEEE Transactions
    on Parallel and Distributed Systems</i>. IEEE. <a href="https://doi.org/10.1109/TPDS.2020.3040606">https://doi.org/10.1109/TPDS.2020.3040606</a>
  chicago: Li, Shigang, Tal Ben-Nun Tal Ben-Nun, Giorgi Nadiradze, Salvatore Di Girolamo,
    Nikoli Dryden, Dan-Adrian Alistarh, and Torsten Hoefler. “Breaking (Global) Barriers
    in Parallel Stochastic Optimization with Wait-Avoiding Group Averaging.” <i>IEEE
    Transactions on Parallel and Distributed Systems</i>. IEEE, 2021. <a href="https://doi.org/10.1109/TPDS.2020.3040606">https://doi.org/10.1109/TPDS.2020.3040606</a>.
  ieee: S. Li <i>et al.</i>, “Breaking (global) barriers in parallel stochastic optimization
    with wait-avoiding group averaging,” <i>IEEE Transactions on Parallel and Distributed
    Systems</i>, vol. 32, no. 7. IEEE, 2021.
  ista: Li S, Tal Ben-Nun TB-N, Nadiradze G, Girolamo SD, Dryden N, Alistarh D-A,
    Hoefler T. 2021. Breaking (global) barriers in parallel stochastic optimization
    with wait-avoiding group averaging. IEEE Transactions on Parallel and Distributed
    Systems. 32(7), 9271898.
  mla: Li, Shigang, et al. “Breaking (Global) Barriers in Parallel Stochastic Optimization
    with Wait-Avoiding Group Averaging.” <i>IEEE Transactions on Parallel and Distributed
    Systems</i>, vol. 32, no. 7, 9271898, IEEE, 2021, doi:<a href="https://doi.org/10.1109/TPDS.2020.3040606">10.1109/TPDS.2020.3040606</a>.
  short: S. Li, T.B.-N. Tal Ben-Nun, G. Nadiradze, S.D. Girolamo, N. Dryden, D.-A.
    Alistarh, T. Hoefler, IEEE Transactions on Parallel and Distributed Systems 32
    (2021).
date_created: 2020-11-05T15:25:43Z
date_published: 2021-07-01T00:00:00Z
date_updated: 2023-08-04T11:08:52Z
day: '01'
department:
- _id: DaAl
doi: 10.1109/TPDS.2020.3040606
ec_funded: 1
external_id:
  arxiv:
  - '2005.00124'
  isi:
  - '000621405200019'
intvolume: '        32'
isi: 1
issue: '7'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/2005.00124
month: '07'
oa: 1
oa_version: Preprint
project:
- _id: 268A44D6-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '805223'
  name: Elastic Coordination for Scalable Machine Learning
publication: IEEE Transactions on Parallel and Distributed Systems
publication_identifier:
  issn:
  - '10459219'
publication_status: published
publisher: IEEE
quality_controlled: '1'
scopus_import: '1'
status: public
title: Breaking (global) barriers in parallel stochastic optimization with wait-avoiding
  group averaging
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 32
year: '2021'
...
---
_id: '8730'
abstract:
- lang: eng
  text: P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) restrict
    at the blood–brain barrier (BBB) the brain distribution of the majority of currently
    known molecularly targeted anticancer drugs. To improve brain delivery of dual
    ABCB1/ABCG2 substrates, both ABCB1 and ABCG2 need to be inhibited simultaneously
    at the BBB. We examined the feasibility of simultaneous ABCB1/ABCG2 inhibition
    with i.v. co-infusion of erlotinib and tariquidar by studying brain distribution
    of the model ABCB1/ABCG2 substrate [11C]erlotinib in mice and rhesus macaques
    with PET. Tolerability of the erlotinib/tariquidar combination was assessed in
    human embryonic stem cell-derived cerebral organoids. In mice and macaques, baseline
    brain distribution of [11C]erlotinib was low (brain distribution volume, VT,brain < 0.3 mL/cm3).
    Co-infusion of erlotinib and tariquidar increased VT,brain in mice by 3.0-fold
    and in macaques by 3.4- to 5.0-fold, while infusion of erlotinib alone or tariquidar
    alone led to less pronounced VT,brain increases in both species. Treatment of
    cerebral organoids with erlotinib/tariquidar led to an induction of Caspase-3-dependent
    apoptosis. Co-infusion of erlotinib/tariquidar may potentially allow for complete
    ABCB1/ABCG2 inhibition at the BBB, while simultaneously achieving brain-targeted
    EGFR inhibition. Our protocol may be applicable to enhance brain delivery of molecularly
    targeted anticancer drugs for a more effective treatment of brain tumors.
article_processing_charge: No
article_type: original
author:
- first_name: N
  full_name: Tournier, N
  last_name: Tournier
- first_name: S
  full_name: Goutal, S
  last_name: Goutal
- first_name: S
  full_name: Mairinger, S
  last_name: Mairinger
- first_name: IH
  full_name: Lozano, IH
  last_name: Lozano
- first_name: T
  full_name: Filip, T
  last_name: Filip
- first_name: M
  full_name: Sauberer, M
  last_name: Sauberer
- first_name: F
  full_name: Caillé, F
  last_name: Caillé
- first_name: L
  full_name: Breuil, L
  last_name: Breuil
- first_name: J
  full_name: Stanek, J
  last_name: Stanek
- first_name: AF
  full_name: Freeman, AF
  last_name: Freeman
- first_name: Gaia
  full_name: Novarino, Gaia
  id: 3E57A680-F248-11E8-B48F-1D18A9856A87
  last_name: Novarino
  orcid: 0000-0002-7673-7178
- first_name: C
  full_name: Truillet, C
  last_name: Truillet
- first_name: T
  full_name: Wanek, T
  last_name: Wanek
- first_name: O
  full_name: Langer, O
  last_name: Langer
citation:
  ama: Tournier N, Goutal S, Mairinger S, et al. Complete inhibition of ABCB1 and
    ABCG2 at the blood-brain barrier by co-infusion of erlotinib and tariquidar to
    improve brain delivery of the model ABCB1/ABCG2 substrate [11C]erlotinib. <i>Journal
    of Cerebral Blood Flow and Metabolism</i>. 2021;41(7):1634-1646. doi:<a href="https://doi.org/10.1177/0271678X20965500">10.1177/0271678X20965500</a>
  apa: Tournier, N., Goutal, S., Mairinger, S., Lozano, I., Filip, T., Sauberer, M.,
    … Langer, O. (2021). Complete inhibition of ABCB1 and ABCG2 at the blood-brain
    barrier by co-infusion of erlotinib and tariquidar to improve brain delivery of
    the model ABCB1/ABCG2 substrate [11C]erlotinib. <i>Journal of Cerebral Blood Flow
    and Metabolism</i>. SAGE Publications. <a href="https://doi.org/10.1177/0271678X20965500">https://doi.org/10.1177/0271678X20965500</a>
  chicago: Tournier, N, S Goutal, S Mairinger, IH Lozano, T Filip, M Sauberer, F Caillé,
    et al. “Complete Inhibition of ABCB1 and ABCG2 at the Blood-Brain Barrier by Co-Infusion
    of Erlotinib and Tariquidar to Improve Brain Delivery of the Model ABCB1/ABCG2
    Substrate [11C]Erlotinib.” <i>Journal of Cerebral Blood Flow and Metabolism</i>.
    SAGE Publications, 2021. <a href="https://doi.org/10.1177/0271678X20965500">https://doi.org/10.1177/0271678X20965500</a>.
  ieee: N. Tournier <i>et al.</i>, “Complete inhibition of ABCB1 and ABCG2 at the
    blood-brain barrier by co-infusion of erlotinib and tariquidar to improve brain
    delivery of the model ABCB1/ABCG2 substrate [11C]erlotinib,” <i>Journal of Cerebral
    Blood Flow and Metabolism</i>, vol. 41, no. 7. SAGE Publications, pp. 1634–1646,
    2021.
  ista: Tournier N, Goutal S, Mairinger S, Lozano I, Filip T, Sauberer M, Caillé F,
    Breuil L, Stanek J, Freeman A, Novarino G, Truillet C, Wanek T, Langer O. 2021.
    Complete inhibition of ABCB1 and ABCG2 at the blood-brain barrier by co-infusion
    of erlotinib and tariquidar to improve brain delivery of the model ABCB1/ABCG2
    substrate [11C]erlotinib. Journal of Cerebral Blood Flow and Metabolism. 41(7),
    1634–1646.
  mla: Tournier, N., et al. “Complete Inhibition of ABCB1 and ABCG2 at the Blood-Brain
    Barrier by Co-Infusion of Erlotinib and Tariquidar to Improve Brain Delivery of
    the Model ABCB1/ABCG2 Substrate [11C]Erlotinib.” <i>Journal of Cerebral Blood
    Flow and Metabolism</i>, vol. 41, no. 7, SAGE Publications, 2021, pp. 1634–46,
    doi:<a href="https://doi.org/10.1177/0271678X20965500">10.1177/0271678X20965500</a>.
  short: N. Tournier, S. Goutal, S. Mairinger, I. Lozano, T. Filip, M. Sauberer, F.
    Caillé, L. Breuil, J. Stanek, A. Freeman, G. Novarino, C. Truillet, T. Wanek,
    O. Langer, Journal of Cerebral Blood Flow and Metabolism 41 (2021) 1634–1646.
date_created: 2020-11-06T08:39:01Z
date_published: 2021-07-01T00:00:00Z
date_updated: 2023-10-18T06:45:30Z
day: '01'
department:
- _id: GaNo
doi: 10.1177/0271678X20965500
external_id:
  isi:
  - '000664214100012'
  pmid:
  - '33081568'
intvolume: '        41'
isi: 1
issue: '7'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8221757/
month: '07'
oa: 1
oa_version: Published Version
page: 1634-1646
pmid: 1
publication: Journal of Cerebral Blood Flow and Metabolism
publication_identifier:
  eissn:
  - 1559-7016
  issn:
  - 0271-678x
publication_status: published
publisher: SAGE Publications
quality_controlled: '1'
scopus_import: '1'
status: public
title: Complete inhibition of ABCB1 and ABCG2 at the blood-brain barrier by co-infusion
  of erlotinib and tariquidar to improve brain delivery of the model ABCB1/ABCG2 substrate
  [11C]erlotinib
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 41
year: '2021'
...
---
_id: '8742'
abstract:
- lang: eng
  text: We develop a version of Ekedahl’s geometric sieve for integral quadratic forms
    of rank at least five. As one ranges over the zeros of such quadratic forms, we
    use the sieve to compute the density of coprime values of polynomials, and furthermore,
    to address a question about local solubility in families of varieties parameterised
    by the zeros.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Timothy D
  full_name: Browning, Timothy D
  id: 35827D50-F248-11E8-B48F-1D18A9856A87
  last_name: Browning
  orcid: 0000-0002-8314-0177
- first_name: Roger
  full_name: Heath-Brown, Roger
  last_name: Heath-Brown
citation:
  ama: Browning TD, Heath-Brown R. The geometric sieve for quadrics. <i>Forum Mathematicum</i>.
    2021;33(1):147-165. doi:<a href="https://doi.org/10.1515/forum-2020-0074">10.1515/forum-2020-0074</a>
  apa: Browning, T. D., &#38; Heath-Brown, R. (2021). The geometric sieve for quadrics.
    <i>Forum Mathematicum</i>. De Gruyter. <a href="https://doi.org/10.1515/forum-2020-0074">https://doi.org/10.1515/forum-2020-0074</a>
  chicago: Browning, Timothy D, and Roger Heath-Brown. “The Geometric Sieve for Quadrics.”
    <i>Forum Mathematicum</i>. De Gruyter, 2021. <a href="https://doi.org/10.1515/forum-2020-0074">https://doi.org/10.1515/forum-2020-0074</a>.
  ieee: T. D. Browning and R. Heath-Brown, “The geometric sieve for quadrics,” <i>Forum
    Mathematicum</i>, vol. 33, no. 1. De Gruyter, pp. 147–165, 2021.
  ista: Browning TD, Heath-Brown R. 2021. The geometric sieve for quadrics. Forum
    Mathematicum. 33(1), 147–165.
  mla: Browning, Timothy D., and Roger Heath-Brown. “The Geometric Sieve for Quadrics.”
    <i>Forum Mathematicum</i>, vol. 33, no. 1, De Gruyter, 2021, pp. 147–65, doi:<a
    href="https://doi.org/10.1515/forum-2020-0074">10.1515/forum-2020-0074</a>.
  short: T.D. Browning, R. Heath-Brown, Forum Mathematicum 33 (2021) 147–165.
date_created: 2020-11-08T23:01:25Z
date_published: 2021-01-01T00:00:00Z
date_updated: 2023-10-17T07:39:01Z
day: '01'
department:
- _id: TiBr
doi: 10.1515/forum-2020-0074
external_id:
  arxiv:
  - '2003.09593'
  isi:
  - '000604750900008'
intvolume: '        33'
isi: 1
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/2003.09593
month: '01'
oa: 1
oa_version: Preprint
page: 147-165
project:
- _id: 26AEDAB2-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: P32428
  name: New frontiers of the Manin conjecture
publication: Forum Mathematicum
publication_identifier:
  eissn:
  - 1435-5337
  issn:
  - 0933-7741
publication_status: published
publisher: De Gruyter
quality_controlled: '1'
scopus_import: '1'
status: public
title: The geometric sieve for quadrics
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 33
year: '2021'
...
---
_id: '8743'
abstract:
- lang: eng
  text: 'Montane cloud forests are areas of high endemism, and are one of the more
    vulnerable terrestrial ecosystems to climate change. Thus, understanding how they
    both contribute to the generation of biodiversity, and will respond to ongoing
    climate change, are important and related challenges. The widely accepted model
    for montane cloud forest dynamics involves upslope forcing of their range limits
    with global climate warming. However, limited climate data provides some support
    for an alternative model, where range limits are forced downslope with climate
    warming. Testing between these two models is challenging, due to the inherent
    limitations of climate and pollen records. We overcome this with an alternative
    source of historical information, testing between competing model predictions
    using genomic data and demographic analyses for a species of beetle tightly associated
    to an oceanic island cloud forest. Results unequivocally support the alternative
    model: populations that were isolated at higher elevation peaks during the Last
    Glacial Maximum are now in contact and hybridizing at lower elevations. Our results
    suggest that genomic data are a rich source of information to further understand
    how montane cloud forest biodiversity originates, and how it is likely to be impacted
    by ongoing climate change.'
acknowledgement: 'This work was financed by the Spanish Agencia Estatal de Investigación
  (CGL2017‐85718‐P), awarded to BCE, and co‐financed by FEDER. It was also supported
  by the Spanish Ministerio de Ciencia, Innovación y Universidades (EQC2018‐004418‐P),
  awarded to BCE. AS‐C was funded by the Spanish Ministerio de Ciencia, Innovación
  y Universidades through an FPU PhD fellowship (FPU014/02948). The authors thank
  Instituto Tecnológico y de Energías Renovables (ITER), S.A for providing access
  to the Teide High‐Performance Computing facility (Teide‐HPC). Fieldwork was supported
  by collecting permit AFF 107/17 (sigma number 2017‐00572) kindly provided by the
  Cabildo of Tenerife. The authors wish to thank the following for field work and
  sample sorting and identification: A. J. Pérez‐Delgado, H. López, and C. Andújar.
  We also thank V. García‐Olivares for assistance with laboratory and bioinformatic
  work.'
article_processing_charge: No
article_type: original
author:
- first_name: Antonia
  full_name: Salces-Castellano, Antonia
  last_name: Salces-Castellano
- first_name: Sean
  full_name: Stankowski, Sean
  id: 43161670-5719-11EA-8025-FABC3DDC885E
  last_name: Stankowski
- first_name: Paula
  full_name: Arribas, Paula
  last_name: Arribas
- first_name: Jairo
  full_name: Patino, Jairo
  last_name: Patino
- first_name: 'Dirk N. '
  full_name: 'Karger, Dirk N. '
  last_name: Karger
- first_name: Roger
  full_name: Butlin, Roger
  last_name: Butlin
- first_name: Brent C.
  full_name: Emerson, Brent C.
  last_name: Emerson
citation:
  ama: Salces-Castellano A, Stankowski S, Arribas P, et al. Long-term cloud forest
    response to climate warming revealed by insect speciation history. <i>Evolution</i>.
    2021;75(2):231-244. doi:<a href="https://doi.org/10.1111/evo.14111">10.1111/evo.14111</a>
  apa: Salces-Castellano, A., Stankowski, S., Arribas, P., Patino, J., Karger, D.
    N., Butlin, R., &#38; Emerson, B. C. (2021). Long-term cloud forest response to
    climate warming revealed by insect speciation history. <i>Evolution</i>. Wiley.
    <a href="https://doi.org/10.1111/evo.14111">https://doi.org/10.1111/evo.14111</a>
  chicago: Salces-Castellano, Antonia, Sean Stankowski, Paula Arribas, Jairo Patino,
    Dirk N.  Karger, Roger Butlin, and Brent C. Emerson. “Long-Term Cloud Forest Response
    to Climate Warming Revealed by Insect Speciation History.” <i>Evolution</i>. Wiley,
    2021. <a href="https://doi.org/10.1111/evo.14111">https://doi.org/10.1111/evo.14111</a>.
  ieee: A. Salces-Castellano <i>et al.</i>, “Long-term cloud forest response to climate
    warming revealed by insect speciation history,” <i>Evolution</i>, vol. 75, no.
    2. Wiley, pp. 231–244, 2021.
  ista: Salces-Castellano A, Stankowski S, Arribas P, Patino J, Karger DN, Butlin
    R, Emerson BC. 2021. Long-term cloud forest response to climate warming revealed
    by insect speciation history. Evolution. 75(2), 231–244.
  mla: Salces-Castellano, Antonia, et al. “Long-Term Cloud Forest Response to Climate
    Warming Revealed by Insect Speciation History.” <i>Evolution</i>, vol. 75, no.
    2, Wiley, 2021, pp. 231–44, doi:<a href="https://doi.org/10.1111/evo.14111">10.1111/evo.14111</a>.
  short: A. Salces-Castellano, S. Stankowski, P. Arribas, J. Patino, D.N. Karger,
    R. Butlin, B.C. Emerson, Evolution 75 (2021) 231–244.
date_created: 2020-11-08T23:01:26Z
date_published: 2021-02-01T00:00:00Z
date_updated: 2023-08-04T11:09:49Z
day: '01'
department:
- _id: NiBa
doi: 10.1111/evo.14111
external_id:
  isi:
  - '000583190600001'
  pmid:
  - '33078844'
intvolume: '        75'
isi: 1
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: http://hdl.handle.net/10261/223937
month: '02'
oa: 1
oa_version: Submitted Version
page: 231-244
pmid: 1
publication: Evolution
publication_identifier:
  eissn:
  - 1558-5646
  issn:
  - 0014-3820
publication_status: published
publisher: Wiley
quality_controlled: '1'
related_material:
  link:
  - relation: erratum
    url: https://doi.org/10.1111/evo.14225
scopus_import: '1'
status: public
title: Long-term cloud forest response to climate warming revealed by insect speciation
  history
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 75
year: '2021'
...
---
_id: '8757'
abstract:
- lang: eng
  text: Traditional scientific conferences and seminar events have been hugely disrupted
    by the COVID-19 pandemic, paving the way for virtual forms of scientific communication
    to take hold and be put to the test.
article_processing_charge: No
article_type: letter_note
author:
- first_name: Panagiotis
  full_name: Bozelos, Panagiotis
  id: 52e9c652-2982-11eb-81d4-b43d94c63700
  last_name: Bozelos
- first_name: Tim P
  full_name: Vogels, Tim P
  id: CB6FF8D2-008F-11EA-8E08-2637E6697425
  last_name: Vogels
  orcid: 0000-0003-3295-6181
citation:
  ama: Bozelos P, Vogels TP. Talking science, online. <i>Nature Reviews Neuroscience</i>.
    2021;22(1):1-2. doi:<a href="https://doi.org/10.1038/s41583-020-00408-6">10.1038/s41583-020-00408-6</a>
  apa: Bozelos, P., &#38; Vogels, T. P. (2021). Talking science, online. <i>Nature
    Reviews Neuroscience</i>. Springer Nature. <a href="https://doi.org/10.1038/s41583-020-00408-6">https://doi.org/10.1038/s41583-020-00408-6</a>
  chicago: Bozelos, Panagiotis, and Tim P Vogels. “Talking Science, Online.” <i>Nature
    Reviews Neuroscience</i>. Springer Nature, 2021. <a href="https://doi.org/10.1038/s41583-020-00408-6">https://doi.org/10.1038/s41583-020-00408-6</a>.
  ieee: P. Bozelos and T. P. Vogels, “Talking science, online,” <i>Nature Reviews
    Neuroscience</i>, vol. 22, no. 1. Springer Nature, pp. 1–2, 2021.
  ista: Bozelos P, Vogels TP. 2021. Talking science, online. Nature Reviews Neuroscience.
    22(1), 1–2.
  mla: Bozelos, Panagiotis, and Tim P. Vogels. “Talking Science, Online.” <i>Nature
    Reviews Neuroscience</i>, vol. 22, no. 1, Springer Nature, 2021, pp. 1–2, doi:<a
    href="https://doi.org/10.1038/s41583-020-00408-6">10.1038/s41583-020-00408-6</a>.
  short: P. Bozelos, T.P. Vogels, Nature Reviews Neuroscience 22 (2021) 1–2.
date_created: 2020-11-15T23:01:18Z
date_published: 2021-01-01T00:00:00Z
date_updated: 2023-08-04T11:10:20Z
day: '01'
ddc:
- '570'
department:
- _id: TiVo
doi: 10.1038/s41583-020-00408-6
external_id:
  isi:
  - '000588256300001'
  pmid:
  - '33173190'
file:
- access_level: open_access
  checksum: 7985d7dff94c086e35b94a911d78d9ad
  content_type: application/pdf
  creator: dernst
  date_created: 2021-02-04T10:34:22Z
  date_updated: 2021-02-04T10:34:22Z
  file_id: '9088'
  file_name: 2021_NatureNeuroScience_Bozelos.pdf
  file_size: 683634
  relation: main_file
  success: 1
file_date_updated: 2021-02-04T10:34:22Z
has_accepted_license: '1'
intvolume: '        22'
isi: 1
issue: '1'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: 1-2
pmid: 1
publication: Nature Reviews Neuroscience
publication_identifier:
  eissn:
  - '14710048'
  issn:
  - 1471003X
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Talking science, online
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 22
year: '2021'
...
---
_id: '8773'
abstract:
- lang: eng
  text: Let g be a complex semisimple Lie algebra. We give a classification of contravariant
    forms on the nondegenerate Whittaker g-modules Y(χ,η) introduced by Kostant. We
    prove that the set of all contravariant forms on Y(χ,η) forms a vector space whose
    dimension is given by the cardinality of the Weyl group of g. We also describe
    a procedure for parabolically inducing contravariant forms. As a corollary, we
    deduce the existence of the Shapovalov form on a Verma module, and provide a formula
    for the dimension of the space of contravariant forms on the degenerate Whittaker
    modules M(χ,η) introduced by McDowell.
acknowledgement: "We would like to thank Peter Trapa for useful discussions, and Dragan
  Milicic and Arun Ram for valuable feedback on the structure of the paper. The first
  author acknowledges the support of the European Unions Horizon 2020 research and
  innovation programme under the Marie Skodowska-Curie Grant Agreement No. 754411.
  The second author is\r\nsupported by the National Science Foundation Award No. 1803059."
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Adam
  full_name: Brown, Adam
  id: 70B7FDF6-608D-11E9-9333-8535E6697425
  last_name: Brown
- first_name: Anna
  full_name: Romanov, Anna
  last_name: Romanov
citation:
  ama: Brown A, Romanov A. Contravariant forms on Whittaker modules. <i>Proceedings
    of the American Mathematical Society</i>. 2021;149(1):37-52. doi:<a href="https://doi.org/10.1090/proc/15205">10.1090/proc/15205</a>
  apa: Brown, A., &#38; Romanov, A. (2021). Contravariant forms on Whittaker modules.
    <i>Proceedings of the American Mathematical Society</i>. American Mathematical
    Society. <a href="https://doi.org/10.1090/proc/15205">https://doi.org/10.1090/proc/15205</a>
  chicago: Brown, Adam, and Anna Romanov. “Contravariant Forms on Whittaker Modules.”
    <i>Proceedings of the American Mathematical Society</i>. American Mathematical
    Society, 2021. <a href="https://doi.org/10.1090/proc/15205">https://doi.org/10.1090/proc/15205</a>.
  ieee: A. Brown and A. Romanov, “Contravariant forms on Whittaker modules,” <i>Proceedings
    of the American Mathematical Society</i>, vol. 149, no. 1. American Mathematical
    Society, pp. 37–52, 2021.
  ista: Brown A, Romanov A. 2021. Contravariant forms on Whittaker modules. Proceedings
    of the American Mathematical Society. 149(1), 37–52.
  mla: Brown, Adam, and Anna Romanov. “Contravariant Forms on Whittaker Modules.”
    <i>Proceedings of the American Mathematical Society</i>, vol. 149, no. 1, American
    Mathematical Society, 2021, pp. 37–52, doi:<a href="https://doi.org/10.1090/proc/15205">10.1090/proc/15205</a>.
  short: A. Brown, A. Romanov, Proceedings of the American Mathematical Society 149
    (2021) 37–52.
date_created: 2020-11-19T10:17:40Z
date_published: 2021-01-01T00:00:00Z
date_updated: 2023-08-04T11:11:47Z
day: '01'
department:
- _id: HeEd
doi: 10.1090/proc/15205
ec_funded: 1
external_id:
  arxiv:
  - '1910.08286'
  isi:
  - '000600416300004'
intvolume: '       149'
isi: 1
issue: '1'
keyword:
- Applied Mathematics
- General Mathematics
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/1910.08286
month: '01'
oa: 1
oa_version: Preprint
page: 37-52
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '754411'
  name: ISTplus - Postdoctoral Fellowships
publication: Proceedings of the American Mathematical Society
publication_identifier:
  eissn:
  - 1088-6826
  issn:
  - 0002-9939
publication_status: published
publisher: American Mathematical Society
quality_controlled: '1'
status: public
title: Contravariant forms on Whittaker modules
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 149
year: '2021'
...
---
_id: '8792'
abstract:
- lang: eng
  text: This paper is concerned with a non-isothermal Cahn-Hilliard model based on
    a microforce balance. The model was derived by A. Miranville and G. Schimperna
    starting from the two fundamental laws of Thermodynamics, following M. Gurtin's
    two-scale approach. The main working assumptions are made on the behaviour of
    the heat flux as the absolute temperature tends to zero and to infinity. A suitable
    Ginzburg-Landau free energy is considered. Global-in-time existence for the initial-boundary
    value problem associated to the entropy formulation and, in a subcase, also to
    the weak formulation of the model is proved by deriving suitable a priori estimates
    and by showing weak sequential stability of families of approximating solutions.
    At last, some highlights are given regarding a possible approximation scheme compatible
    with the a-priori estimates available for the system.
acknowledgement: G. Schimperna has been partially supported by GNAMPA (Gruppo Nazionale
  per l'Analisi Matematica, la Probabilità e le loro Applicazioni) of INdAM (Istituto
  Nazionale di Alta Matematica).
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Alice
  full_name: Marveggio, Alice
  id: 25647992-AA84-11E9-9D75-8427E6697425
  last_name: Marveggio
- first_name: Giulio
  full_name: Schimperna, Giulio
  last_name: Schimperna
citation:
  ama: Marveggio A, Schimperna G. On a non-isothermal Cahn-Hilliard model based on
    a microforce balance. <i>Journal of Differential Equations</i>. 2021;274(2):924-970.
    doi:<a href="https://doi.org/10.1016/j.jde.2020.10.030">10.1016/j.jde.2020.10.030</a>
  apa: Marveggio, A., &#38; Schimperna, G. (2021). On a non-isothermal Cahn-Hilliard
    model based on a microforce balance. <i>Journal of Differential Equations</i>.
    Elsevier. <a href="https://doi.org/10.1016/j.jde.2020.10.030">https://doi.org/10.1016/j.jde.2020.10.030</a>
  chicago: Marveggio, Alice, and Giulio Schimperna. “On a Non-Isothermal Cahn-Hilliard
    Model Based on a Microforce Balance.” <i>Journal of Differential Equations</i>.
    Elsevier, 2021. <a href="https://doi.org/10.1016/j.jde.2020.10.030">https://doi.org/10.1016/j.jde.2020.10.030</a>.
  ieee: A. Marveggio and G. Schimperna, “On a non-isothermal Cahn-Hilliard model based
    on a microforce balance,” <i>Journal of Differential Equations</i>, vol. 274,
    no. 2. Elsevier, pp. 924–970, 2021.
  ista: Marveggio A, Schimperna G. 2021. On a non-isothermal Cahn-Hilliard model based
    on a microforce balance. Journal of Differential Equations. 274(2), 924–970.
  mla: Marveggio, Alice, and Giulio Schimperna. “On a Non-Isothermal Cahn-Hilliard
    Model Based on a Microforce Balance.” <i>Journal of Differential Equations</i>,
    vol. 274, no. 2, Elsevier, 2021, pp. 924–70, doi:<a href="https://doi.org/10.1016/j.jde.2020.10.030">10.1016/j.jde.2020.10.030</a>.
  short: A. Marveggio, G. Schimperna, Journal of Differential Equations 274 (2021)
    924–970.
date_created: 2020-11-22T23:01:26Z
date_published: 2021-02-15T00:00:00Z
date_updated: 2023-08-04T11:12:16Z
day: '15'
department:
- _id: JuFi
doi: 10.1016/j.jde.2020.10.030
external_id:
  arxiv:
  - '2004.02618'
  isi:
  - '000600845300023'
intvolume: '       274'
isi: 1
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/2004.02618
month: '02'
oa: 1
oa_version: Preprint
page: 924-970
publication: Journal of Differential Equations
publication_identifier:
  eissn:
  - '10902732'
  issn:
  - '00220396'
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: On a non-isothermal Cahn-Hilliard model based on a microforce balance
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 274
year: '2021'
...
---
_id: '8793'
abstract:
- lang: eng
  text: We study optimal election sequences for repeatedly selecting a (very) small
    group of leaders among a set of participants (players) with publicly known unique
    ids. In every time slot, every player has to select exactly one player that it
    considers to be the current leader, oblivious to the selection of the other players,
    but with the overarching goal of maximizing a given parameterized global (“social”)
    payoff function in the limit. We consider a quite generic model, where the local
    payoff achieved by a given player depends, weighted by some arbitrary but fixed
    real parameter, on the number of different leaders chosen in a round, the number
    of players that choose the given player as the leader, and whether the chosen
    leader has changed w.r.t. the previous round or not. The social payoff can be
    the maximum, average or minimum local payoff of the players. Possible applications
    include quite diverse examples such as rotating coordinator-based distributed
    algorithms and long-haul formation flying of social birds. Depending on the weights
    and the particular social payoff, optimal sequences can be very different, from
    simple round-robin where all players chose the same leader alternatingly every
    time slot to very exotic patterns, where a small group of leaders (at most 2)
    is elected in every time slot. Moreover, we study the question if and when a single
    player would not benefit w.r.t. its local payoff when deviating from the given
    optimal sequence, i.e., when our optimal sequences are Nash equilibria in the
    restricted strategy space of oblivious strategies. As this is the case for many
    parameterizations of our model, our results reveal that no punishment is needed
    to make it rational for the players to optimize the social payoff.
acknowledgement: "We are grateful to Matthias Függer and Thomas Nowak for having raised
  our interest in the problem studied in this paper.\r\nThis work has been supported
  the Austrian Science Fund (FWF) projects S11405, S11407 (RiSE), and P28182 (ADynNet)."
article_processing_charge: No
article_type: original
author:
- first_name: Martin
  full_name: Zeiner, Martin
  last_name: Zeiner
- first_name: Ulrich
  full_name: Schmid, Ulrich
  last_name: Schmid
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
citation:
  ama: Zeiner M, Schmid U, Chatterjee K. Optimal strategies for selecting coordinators.
    <i>Discrete Applied Mathematics</i>. 2021;289(1):392-415. doi:<a href="https://doi.org/10.1016/j.dam.2020.10.022">10.1016/j.dam.2020.10.022</a>
  apa: Zeiner, M., Schmid, U., &#38; Chatterjee, K. (2021). Optimal strategies for
    selecting coordinators. <i>Discrete Applied Mathematics</i>. Elsevier. <a href="https://doi.org/10.1016/j.dam.2020.10.022">https://doi.org/10.1016/j.dam.2020.10.022</a>
  chicago: Zeiner, Martin, Ulrich Schmid, and Krishnendu Chatterjee. “Optimal Strategies
    for Selecting Coordinators.” <i>Discrete Applied Mathematics</i>. Elsevier, 2021.
    <a href="https://doi.org/10.1016/j.dam.2020.10.022">https://doi.org/10.1016/j.dam.2020.10.022</a>.
  ieee: M. Zeiner, U. Schmid, and K. Chatterjee, “Optimal strategies for selecting
    coordinators,” <i>Discrete Applied Mathematics</i>, vol. 289, no. 1. Elsevier,
    pp. 392–415, 2021.
  ista: Zeiner M, Schmid U, Chatterjee K. 2021. Optimal strategies for selecting coordinators.
    Discrete Applied Mathematics. 289(1), 392–415.
  mla: Zeiner, Martin, et al. “Optimal Strategies for Selecting Coordinators.” <i>Discrete
    Applied Mathematics</i>, vol. 289, no. 1, Elsevier, 2021, pp. 392–415, doi:<a
    href="https://doi.org/10.1016/j.dam.2020.10.022">10.1016/j.dam.2020.10.022</a>.
  short: M. Zeiner, U. Schmid, K. Chatterjee, Discrete Applied Mathematics 289 (2021)
    392–415.
date_created: 2020-11-22T23:01:26Z
date_published: 2021-01-31T00:00:00Z
date_updated: 2023-08-04T11:12:41Z
day: '31'
ddc:
- '510'
department:
- _id: KrCh
doi: 10.1016/j.dam.2020.10.022
external_id:
  isi:
  - '000596823800035'
file:
- access_level: open_access
  checksum: f1039ff5a2d6ca116720efdb84ee9d5e
  content_type: application/pdf
  creator: dernst
  date_created: 2021-02-04T11:28:42Z
  date_updated: 2021-02-04T11:28:42Z
  file_id: '9089'
  file_name: 2021_DiscreteApplMath_Zeiner.pdf
  file_size: 652739
  relation: main_file
  success: 1
file_date_updated: 2021-02-04T11:28:42Z
has_accepted_license: '1'
intvolume: '       289'
isi: 1
issue: '1'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: 392-415
project:
- _id: 25F2ACDE-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: S11402-N23
  name: Rigorous Systems Engineering
- _id: 25863FF4-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: S11407
  name: Game Theory
publication: Discrete Applied Mathematics
publication_identifier:
  issn:
  - 0166218X
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Optimal strategies for selecting coordinators
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 289
year: '2021'
...
---
_id: '8816'
abstract:
- lang: eng
  text: Area-dependent quantum field theory is a modification of two-dimensional topological
    quantum field theory, where one equips each connected component of a bordism with
    a positive real number—interpreted as area—which behaves additively under glueing.
    As opposed to topological theories, in area-dependent theories the state spaces
    can be infinite-dimensional. We introduce the notion of regularised Frobenius
    algebras in Hilbert spaces and show that area-dependent theories are in one-to-one
    correspondence to commutative regularised Frobenius algebras. We also provide
    a state sum construction for area-dependent theories. Our main example is two-dimensional
    Yang–Mills theory with compact gauge group, which we treat in detail.
acknowledgement: The authors thank Yuki Arano, Nils Carqueville, Alexei Davydov, Reiner
  Lauterbach, Pau Enrique Moliner, Chris Heunen, André Henriques, Ehud Meir, Catherine
  Meusburger, Gregor Schaumann, Richard Szabo and Stefan Wagner for helpful discussions
  and comments. We also thank the referees for their detailed comments which significantly
  improved the exposition of this paper. LS is supported by the DFG Research Training
  Group 1670 “Mathematics Inspired by String Theory and Quantum Field Theory”. Open
  access funding provided by Institute of Science and Technology (IST Austria).
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Ingo
  full_name: Runkel, Ingo
  last_name: Runkel
- first_name: Lorant
  full_name: Szegedy, Lorant
  id: 7943226E-220E-11EA-94C7-D59F3DDC885E
  last_name: Szegedy
  orcid: 0000-0003-2834-5054
citation:
  ama: Runkel I, Szegedy L. Area-dependent quantum field theory. <i>Communications
    in Mathematical Physics</i>. 2021;381(1):83–117. doi:<a href="https://doi.org/10.1007/s00220-020-03902-1">10.1007/s00220-020-03902-1</a>
  apa: Runkel, I., &#38; Szegedy, L. (2021). Area-dependent quantum field theory.
    <i>Communications in Mathematical Physics</i>. Springer Nature. <a href="https://doi.org/10.1007/s00220-020-03902-1">https://doi.org/10.1007/s00220-020-03902-1</a>
  chicago: Runkel, Ingo, and Lorant Szegedy. “Area-Dependent Quantum Field Theory.”
    <i>Communications in Mathematical Physics</i>. Springer Nature, 2021. <a href="https://doi.org/10.1007/s00220-020-03902-1">https://doi.org/10.1007/s00220-020-03902-1</a>.
  ieee: I. Runkel and L. Szegedy, “Area-dependent quantum field theory,” <i>Communications
    in Mathematical Physics</i>, vol. 381, no. 1. Springer Nature, pp. 83–117, 2021.
  ista: Runkel I, Szegedy L. 2021. Area-dependent quantum field theory. Communications
    in Mathematical Physics. 381(1), 83–117.
  mla: Runkel, Ingo, and Lorant Szegedy. “Area-Dependent Quantum Field Theory.” <i>Communications
    in Mathematical Physics</i>, vol. 381, no. 1, Springer Nature, 2021, pp. 83–117,
    doi:<a href="https://doi.org/10.1007/s00220-020-03902-1">10.1007/s00220-020-03902-1</a>.
  short: I. Runkel, L. Szegedy, Communications in Mathematical Physics 381 (2021)
    83–117.
date_created: 2020-11-29T23:01:17Z
date_published: 2021-01-01T00:00:00Z
date_updated: 2023-08-04T11:13:35Z
day: '01'
ddc:
- '510'
department:
- _id: MiLe
doi: 10.1007/s00220-020-03902-1
external_id:
  isi:
  - '000591139000001'
file:
- access_level: open_access
  checksum: 6f451f9c2b74bedbc30cf884a3e02670
  content_type: application/pdf
  creator: dernst
  date_created: 2021-02-03T15:00:30Z
  date_updated: 2021-02-03T15:00:30Z
  file_id: '9081'
  file_name: 2021_CommMathPhys_Runkel.pdf
  file_size: 790526
  relation: main_file
  success: 1
file_date_updated: 2021-02-03T15:00:30Z
has_accepted_license: '1'
intvolume: '       381'
isi: 1
issue: '1'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: 83–117
project:
- _id: B67AFEDC-15C9-11EA-A837-991A96BB2854
  name: IST Austria Open Access Fund
publication: Communications in Mathematical Physics
publication_identifier:
  eissn:
  - '14320916'
  issn:
  - '00103616'
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Area-dependent quantum field theory
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 381
year: '2021'
...
---
_id: '8817'
abstract:
- lang: eng
  text: The paper introduces an inertial extragradient subgradient method with self-adaptive
    step sizes for solving equilibrium problems in real Hilbert spaces. Weak convergence
    of the proposed method is obtained under the condition that the bifunction is
    pseudomonotone and Lipchitz continuous. Linear convergence is also given when
    the bifunction is strongly pseudomonotone and Lipchitz continuous. Numerical implementations
    and comparisons with other related inertial methods are given using test problems
    including a real-world application to Nash–Cournot oligopolistic electricity market
    equilibrium model.
acknowledgement: The authors are grateful to the two referees and the Associate Editor
  for their comments and suggestions which have improved the earlier version of the
  paper greatly. The project of Yekini Shehu has received funding from the European
  Research Council (ERC) under the European Union’s Seventh Framework Program (FP7
  - 2007-2013) (Grant agreement No. 616160).
article_processing_charge: No
article_type: original
author:
- first_name: Yekini
  full_name: Shehu, Yekini
  id: 3FC7CB58-F248-11E8-B48F-1D18A9856A87
  last_name: Shehu
  orcid: 0000-0001-9224-7139
- first_name: Olaniyi S.
  full_name: Iyiola, Olaniyi S.
  last_name: Iyiola
- first_name: Duong Viet
  full_name: Thong, Duong Viet
  last_name: Thong
- first_name: Nguyen Thi Cam
  full_name: Van, Nguyen Thi Cam
  last_name: Van
citation:
  ama: Shehu Y, Iyiola OS, Thong DV, Van NTC. An inertial subgradient extragradient
    algorithm extended to pseudomonotone equilibrium problems. <i>Mathematical Methods
    of Operations Research</i>. 2021;93(2):213-242. doi:<a href="https://doi.org/10.1007/s00186-020-00730-w">10.1007/s00186-020-00730-w</a>
  apa: Shehu, Y., Iyiola, O. S., Thong, D. V., &#38; Van, N. T. C. (2021). An inertial
    subgradient extragradient algorithm extended to pseudomonotone equilibrium problems.
    <i>Mathematical Methods of Operations Research</i>. Springer Nature. <a href="https://doi.org/10.1007/s00186-020-00730-w">https://doi.org/10.1007/s00186-020-00730-w</a>
  chicago: Shehu, Yekini, Olaniyi S. Iyiola, Duong Viet Thong, and Nguyen Thi Cam
    Van. “An Inertial Subgradient Extragradient Algorithm Extended to Pseudomonotone
    Equilibrium Problems.” <i>Mathematical Methods of Operations Research</i>. Springer
    Nature, 2021. <a href="https://doi.org/10.1007/s00186-020-00730-w">https://doi.org/10.1007/s00186-020-00730-w</a>.
  ieee: Y. Shehu, O. S. Iyiola, D. V. Thong, and N. T. C. Van, “An inertial subgradient
    extragradient algorithm extended to pseudomonotone equilibrium problems,” <i>Mathematical
    Methods of Operations Research</i>, vol. 93, no. 2. Springer Nature, pp. 213–242,
    2021.
  ista: Shehu Y, Iyiola OS, Thong DV, Van NTC. 2021. An inertial subgradient extragradient
    algorithm extended to pseudomonotone equilibrium problems. Mathematical Methods
    of Operations Research. 93(2), 213–242.
  mla: Shehu, Yekini, et al. “An Inertial Subgradient Extragradient Algorithm Extended
    to Pseudomonotone Equilibrium Problems.” <i>Mathematical Methods of Operations
    Research</i>, vol. 93, no. 2, Springer Nature, 2021, pp. 213–42, doi:<a href="https://doi.org/10.1007/s00186-020-00730-w">10.1007/s00186-020-00730-w</a>.
  short: Y. Shehu, O.S. Iyiola, D.V. Thong, N.T.C. Van, Mathematical Methods of Operations
    Research 93 (2021) 213–242.
date_created: 2020-11-29T23:01:18Z
date_published: 2021-04-01T00:00:00Z
date_updated: 2023-10-10T09:30:23Z
day: '01'
department:
- _id: VlKo
doi: 10.1007/s00186-020-00730-w
ec_funded: 1
external_id:
  isi:
  - '000590497300001'
intvolume: '        93'
isi: 1
issue: '2'
language:
- iso: eng
month: '04'
oa_version: None
page: 213-242
project:
- _id: 25FBA906-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '616160'
  name: 'Discrete Optimization in Computer Vision: Theory and Practice'
publication: Mathematical Methods of Operations Research
publication_identifier:
  eissn:
  - 1432-5217
  issn:
  - 1432-2994
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: An inertial subgradient extragradient algorithm extended to pseudomonotone
  equilibrium problems
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 93
year: '2021'
...
