[{"month":"01","arxiv":1,"department":[{"_id":"GradSch"},{"_id":"LaEr"}],"file":[{"file_id":"10647","date_updated":"2022-01-19T09:41:14Z","creator":"cchlebak","file_size":357547,"date_created":"2022-01-19T09:41:14Z","checksum":"7e8e69b76e892c305071a4736131fe18","relation":"main_file","content_type":"application/pdf","access_level":"open_access","file_name":"2022_LettersMathPhys_Henheik.pdf","success":1}],"article_number":"9","oa":1,"language":[{"iso":"eng"}],"citation":{"mla":"Henheik, Sven Joscha, et al. “Local Stability of Ground States in Locally Gapped and Weakly Interacting Quantum Spin Systems.” <i>Letters in Mathematical Physics</i>, vol. 112, no. 1, 9, Springer Nature, 2022, doi:<a href=\"https://doi.org/10.1007/s11005-021-01494-y\">10.1007/s11005-021-01494-y</a>.","apa":"Henheik, S. J., Teufel, S., &#38; Wessel, T. (2022). Local stability of ground states in locally gapped and weakly interacting quantum spin systems. <i>Letters in Mathematical Physics</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s11005-021-01494-y\">https://doi.org/10.1007/s11005-021-01494-y</a>","ista":"Henheik SJ, Teufel S, Wessel T. 2022. Local stability of ground states in locally gapped and weakly interacting quantum spin systems. Letters in Mathematical Physics. 112(1), 9.","chicago":"Henheik, Sven Joscha, Stefan Teufel, and Tom Wessel. “Local Stability of Ground States in Locally Gapped and Weakly Interacting Quantum Spin Systems.” <i>Letters in Mathematical Physics</i>. Springer Nature, 2022. <a href=\"https://doi.org/10.1007/s11005-021-01494-y\">https://doi.org/10.1007/s11005-021-01494-y</a>.","short":"S.J. Henheik, S. Teufel, T. Wessel, Letters in Mathematical Physics 112 (2022).","ieee":"S. J. Henheik, S. Teufel, and T. Wessel, “Local stability of ground states in locally gapped and weakly interacting quantum spin systems,” <i>Letters in Mathematical Physics</i>, vol. 112, no. 1. Springer Nature, 2022.","ama":"Henheik SJ, Teufel S, Wessel T. Local stability of ground states in locally gapped and weakly interacting quantum spin systems. <i>Letters in Mathematical Physics</i>. 2022;112(1). doi:<a href=\"https://doi.org/10.1007/s11005-021-01494-y\">10.1007/s11005-021-01494-y</a>"},"issue":"1","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","day":"18","author":[{"last_name":"Henheik","id":"31d731d7-d235-11ea-ad11-b50331c8d7fb","full_name":"Henheik, Sven Joscha","orcid":"0000-0003-1106-327X","first_name":"Sven Joscha"},{"last_name":"Teufel","full_name":"Teufel, Stefan","first_name":"Stefan"},{"last_name":"Wessel","full_name":"Wessel, Tom","first_name":"Tom"}],"oa_version":"Published Version","title":"Local stability of ground states in locally gapped and weakly interacting quantum spin systems","volume":112,"date_created":"2022-01-18T16:18:25Z","article_type":"original","has_accepted_license":"1","intvolume":"       112","license":"https://creativecommons.org/licenses/by/4.0/","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","short":"CC BY (4.0)"},"abstract":[{"text":"Based on a result by Yarotsky (J Stat Phys 118, 2005), we prove that localized but otherwise arbitrary perturbations of weakly interacting quantum spin systems with uniformly gapped on-site terms change the ground state of such a system only locally, even if they close the spectral gap. We call this a strong version of the local perturbations perturb locally (LPPL) principle which is known to hold for much more general gapped systems, but only for perturbations that do not close the spectral gap of the Hamiltonian. We also extend this strong LPPL-principle to Hamiltonians that have the appropriate structure of gapped on-site terms and weak interactions only locally in some region of space. While our results are technically corollaries to a theorem of Yarotsky, we expect that the paradigm of systems with a locally gapped ground state that is completely insensitive to the form of the Hamiltonian elsewhere extends to other situations and has important physical consequences.","lang":"eng"}],"file_date_updated":"2022-01-19T09:41:14Z","publication_identifier":{"eissn":["1573-0530"],"issn":["0377-9017"]},"publication_status":"published","year":"2022","isi":1,"external_id":{"isi":["000744930400001"],"arxiv":["2106.13780"]},"keyword":["mathematical physics","statistical and nonlinear physics"],"publication":"Letters in Mathematical Physics","status":"public","project":[{"_id":"62796744-2b32-11ec-9570-940b20777f1d","name":"Random matrices beyond Wigner-Dyson-Mehta","grant_number":"101020331","call_identifier":"H2020"}],"ec_funded":1,"acknowledgement":"J. H. acknowledges partial financial support by the ERC Advanced Grant “RMTBeyond” No. 101020331. S. T. thanks Marius Lemm and Simone Warzel for very helpful comments and discussions and Jürg Fröhlich for references to the literature. Open Access funding enabled and organized by Projekt DEAL.","date_published":"2022-01-18T00:00:00Z","article_processing_charge":"No","doi":"10.1007/s11005-021-01494-y","publisher":"Springer Nature","_id":"10642","date_updated":"2023-08-02T13:57:02Z","type":"journal_article","ddc":["530"],"quality_controlled":"1"},{"ddc":["510"],"quality_controlled":"1","doi":"10.1017/fms.2021.80","article_processing_charge":"Yes","publisher":"Cambridge University Press","date_updated":"2023-08-02T13:53:11Z","_id":"10643","type":"journal_article","project":[{"_id":"62796744-2b32-11ec-9570-940b20777f1d","call_identifier":"H2020","name":"Random matrices beyond Wigner-Dyson-Mehta","grant_number":"101020331"}],"publication":"Forum of Mathematics, Sigma","status":"public","ec_funded":1,"date_published":"2022-01-18T00:00:00Z","acknowledgement":"J.H. acknowledges partial financial support by the ERC Advanced Grant ‘RMTBeyond’ No. 101020331. Support for publication costs from the Deutsche Forschungsgemeinschaft and the Open Access Publishing Fund of the University of Tübingen is gratefully acknowledged.","year":"2022","isi":1,"external_id":{"arxiv":["2012.15239"],"isi":["000743615000001"]},"keyword":["computational mathematics","discrete mathematics and combinatorics","geometry and topology","mathematical physics","statistics and probability","algebra and number theory","theoretical computer science","analysis"],"has_accepted_license":"1","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","short":"CC BY (4.0)"},"intvolume":"        10","abstract":[{"lang":"eng","text":"We prove a generalised super-adiabatic theorem for extended fermionic systems assuming a spectral gap only in the bulk. More precisely, we assume that the infinite system has a unique ground state and that the corresponding Gelfand–Naimark–Segal Hamiltonian has a spectral gap above its eigenvalue zero. Moreover, we show that a similar adiabatic theorem also holds in the bulk of finite systems up to errors that vanish faster than any inverse power of the system size, although the corresponding finite-volume Hamiltonians need not have a spectral gap.\r\n\r\n"}],"publication_status":"published","publication_identifier":{"eissn":["2050-5094"]},"file_date_updated":"2022-01-19T09:27:43Z","author":[{"last_name":"Henheik","full_name":"Henheik, Sven Joscha","id":"31d731d7-d235-11ea-ad11-b50331c8d7fb","orcid":"0000-0003-1106-327X","first_name":"Sven Joscha"},{"last_name":"Teufel","full_name":"Teufel, Stefan","first_name":"Stefan"}],"day":"18","title":"Adiabatic theorem in the thermodynamic limit: Systems with a gap in the bulk","oa_version":"Published Version","volume":10,"article_type":"original","date_created":"2022-01-18T16:18:51Z","oa":1,"language":[{"iso":"eng"}],"citation":{"ama":"Henheik SJ, Teufel S. Adiabatic theorem in the thermodynamic limit: Systems with a gap in the bulk. <i>Forum of Mathematics, Sigma</i>. 2022;10. doi:<a href=\"https://doi.org/10.1017/fms.2021.80\">10.1017/fms.2021.80</a>","short":"S.J. Henheik, S. Teufel, Forum of Mathematics, Sigma 10 (2022).","ieee":"S. J. Henheik and S. Teufel, “Adiabatic theorem in the thermodynamic limit: Systems with a gap in the bulk,” <i>Forum of Mathematics, Sigma</i>, vol. 10. Cambridge University Press, 2022.","chicago":"Henheik, Sven Joscha, and Stefan Teufel. “Adiabatic Theorem in the Thermodynamic Limit: Systems with a Gap in the Bulk.” <i>Forum of Mathematics, Sigma</i>. Cambridge University Press, 2022. <a href=\"https://doi.org/10.1017/fms.2021.80\">https://doi.org/10.1017/fms.2021.80</a>.","ista":"Henheik SJ, Teufel S. 2022. Adiabatic theorem in the thermodynamic limit: Systems with a gap in the bulk. Forum of Mathematics, Sigma. 10, e4.","mla":"Henheik, Sven Joscha, and Stefan Teufel. “Adiabatic Theorem in the Thermodynamic Limit: Systems with a Gap in the Bulk.” <i>Forum of Mathematics, Sigma</i>, vol. 10, e4, Cambridge University Press, 2022, doi:<a href=\"https://doi.org/10.1017/fms.2021.80\">10.1017/fms.2021.80</a>.","apa":"Henheik, S. J., &#38; Teufel, S. (2022). Adiabatic theorem in the thermodynamic limit: Systems with a gap in the bulk. <i>Forum of Mathematics, Sigma</i>. Cambridge University Press. <a href=\"https://doi.org/10.1017/fms.2021.80\">https://doi.org/10.1017/fms.2021.80</a>"},"user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","arxiv":1,"month":"01","department":[{"_id":"GradSch"},{"_id":"LaEr"}],"file":[{"checksum":"87592a755adcef22ea590a99dc728dd3","relation":"main_file","content_type":"application/pdf","access_level":"open_access","file_name":"2022_ForumMathSigma_Henheik.pdf","success":1,"file_id":"10646","creator":"cchlebak","date_updated":"2022-01-19T09:27:43Z","file_size":705323,"date_created":"2022-01-19T09:27:43Z"}],"article_number":"e4"},{"date_updated":"2022-05-16T11:21:38Z","_id":"10652","type":"journal_article","doi":"10.1103/PhysRevResearch.4.013023","article_processing_charge":"Yes (via OA deal)","publisher":"American Physical Society","quality_controlled":"1","ddc":["530"],"year":"2022","date_published":"2022-01-10T00:00:00Z","acknowledgement":"O.H. is supported by Institute of Science and Technology Austria. The author thanks Jess Riedel for discussions.","publication":"Physical Review Research","status":"public","volume":4,"article_type":"original","date_created":"2022-01-23T23:01:27Z","author":[{"id":"4C02D85E-F248-11E8-B48F-1D18A9856A87","full_name":"Hosten, Onur","last_name":"Hosten","orcid":"0000-0002-2031-204X","first_name":"Onur"}],"scopus_import":"1","day":"10","title":"Constraints on probing quantum coherence to infer gravitational entanglement","oa_version":"Published Version","publication_identifier":{"issn":["2643-1564"]},"publication_status":"published","file_date_updated":"2022-01-24T11:12:44Z","has_accepted_license":"1","abstract":[{"text":"Finding a feasible scheme for testing the quantum mechanical nature of the gravitational interaction has been attracting an increasing level of attention. Gravity mediated entanglement generation so far appears to be the key ingredient for a potential experiment. In a recent proposal [D. Carney et al., PRX Quantum 2, 030330 (2021)] combining an atom interferometer with a low-frequency mechanical oscillator, a coherence revival test is proposed for verifying this entanglement generation. With measurements performed only on the atoms, this protocol bypasses the need for correlation measurements. Here, we explore formulations of such a protocol, and specifically find that in the envisioned regime of operation with high thermal excitation, semiclassical models, where there is no concept of entanglement, also give the same experimental signatures. We elucidate in a fully quantum mechanical calculation that entanglement is not the source of the revivals in the relevant parameter regime. We argue that, in its current form, the suggested test is only relevant if the oscillator is nearly in a pure quantum state, and in this regime the effects are too small to be measurable. We further discuss potential open ends. The results highlight the importance and subtleties of explicitly considering how the quantum case differs from the classical expectations when testing for the quantum mechanical nature of a physical system.","lang":"eng"}],"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","short":"CC BY (4.0)"},"intvolume":"         4","department":[{"_id":"OnHo"}],"file":[{"file_id":"10660","date_created":"2022-01-24T11:12:44Z","file_size":236329,"date_updated":"2022-01-24T11:12:44Z","creator":"cchlebak","relation":"main_file","checksum":"7254d267a0633ca5d63131d345e58686","file_name":"2022_PhysRevResearch_Hosten.pdf","success":1,"content_type":"application/pdf","access_level":"open_access"}],"article_number":"013023","month":"01","issue":"1","citation":{"ieee":"O. Hosten, “Constraints on probing quantum coherence to infer gravitational entanglement,” <i>Physical Review Research</i>, vol. 4, no. 1. American Physical Society, 2022.","short":"O. Hosten, Physical Review Research 4 (2022).","ama":"Hosten O. Constraints on probing quantum coherence to infer gravitational entanglement. <i>Physical Review Research</i>. 2022;4(1). doi:<a href=\"https://doi.org/10.1103/PhysRevResearch.4.013023\">10.1103/PhysRevResearch.4.013023</a>","apa":"Hosten, O. (2022). Constraints on probing quantum coherence to infer gravitational entanglement. <i>Physical Review Research</i>. American Physical Society. <a href=\"https://doi.org/10.1103/PhysRevResearch.4.013023\">https://doi.org/10.1103/PhysRevResearch.4.013023</a>","mla":"Hosten, Onur. “Constraints on Probing Quantum Coherence to Infer Gravitational Entanglement.” <i>Physical Review Research</i>, vol. 4, no. 1, 013023, American Physical Society, 2022, doi:<a href=\"https://doi.org/10.1103/PhysRevResearch.4.013023\">10.1103/PhysRevResearch.4.013023</a>.","chicago":"Hosten, Onur. “Constraints on Probing Quantum Coherence to Infer Gravitational Entanglement.” <i>Physical Review Research</i>. American Physical Society, 2022. <a href=\"https://doi.org/10.1103/PhysRevResearch.4.013023\">https://doi.org/10.1103/PhysRevResearch.4.013023</a>.","ista":"Hosten O. 2022. Constraints on probing quantum coherence to infer gravitational entanglement. Physical Review Research. 4(1), 013023."},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa":1,"language":[{"iso":"eng"}]},{"ddc":["550"],"quality_controlled":"1","publisher":"Wiley","doi":"10.1029/2021GL095184","article_processing_charge":"No","type":"journal_article","date_updated":"2023-08-02T14:00:17Z","_id":"10653","project":[{"grant_number":"805041","name":"organization of CLoUdS, and implications of Tropical  cyclones and for the Energetics of the tropics, in current and waRming climate","call_identifier":"H2020","_id":"629205d8-2b32-11ec-9570-e1356ff73576"}],"publication":"Geophysical Research Letters","status":"public","acknowledgement":"The authors gratefully acknowledge funding from the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation program (Project CLUSTER, Grant Agreement No. 805041), and from the PhD fellowship of Ecole Normale Supérieure de Paris-Saclay. Two supplementary movies are also provided showing the angle detection method and the squall line of the Usfc = 10 m s−1 simulation.","date_published":"2022-01-16T00:00:00Z","ec_funded":1,"external_id":{"isi":["000743989800040"]},"related_material":{"link":[{"url":"https://doi.org/10.1002/essoar.10507697.1","relation":"earlier_version"}]},"year":"2022","isi":1,"abstract":[{"text":"Squall lines are known to be the consequence of the interaction of low-level shear with cold pools associated with convective downdrafts. Also, as the magnitude of the shear increases beyond a critical shear, squall lines tend to orient themselves. The existing literature suggests that this orientation reduces incoming wind shear to the squall line, and maintains equilibrium between wind shear and cold pool spreading. Although this theory is widely accepted, very few quantitative studies have been conducted on supercritical regime especially. Here, we test this hypothesis with tropical squall lines obtained by imposing a vertical wind shear in cloud resolving simulations in radiative convective equilibrium. In the sub-critical regime, squall lines are perpendicular to the shear. In the super-critical regime, their orientation maintain the equilibrium, supporting existing theories. We also find that as shear increases, cold pools become more intense. However, this intensification has little impact on squall line orientation.","lang":"eng"}],"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","short":"CC BY (4.0)"},"intvolume":"        49","has_accepted_license":"1","publication_identifier":{"issn":["0094-8276"],"eissn":["1944-8007"]},"publication_status":"published","file_date_updated":"2022-01-24T12:14:41Z","title":"Shear-convection interactions and orientation of tropical squall lines","oa_version":"Published Version","author":[{"last_name":"Abramian","full_name":"Abramian, Sophie","first_name":"Sophie"},{"last_name":"Muller","id":"f978ccb0-3f7f-11eb-b193-b0e2bd13182b","full_name":"Muller, Caroline J","first_name":"Caroline J","orcid":"0000-0001-5836-5350"},{"last_name":"Risi","full_name":"Risi, Camille","first_name":"Camille"}],"scopus_import":"1","day":"16","article_type":"original","date_created":"2022-01-23T23:01:27Z","volume":49,"language":[{"iso":"eng"}],"oa":1,"user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","issue":"1","citation":{"ista":"Abramian S, Muller CJ, Risi C. 2022. Shear-convection interactions and orientation of tropical squall lines. Geophysical Research Letters. 49(1), e2021GL095184.","chicago":"Abramian, Sophie, Caroline J Muller, and Camille Risi. “Shear-Convection Interactions and Orientation of Tropical Squall Lines.” <i>Geophysical Research Letters</i>. Wiley, 2022. <a href=\"https://doi.org/10.1029/2021GL095184\">https://doi.org/10.1029/2021GL095184</a>.","mla":"Abramian, Sophie, et al. “Shear-Convection Interactions and Orientation of Tropical Squall Lines.” <i>Geophysical Research Letters</i>, vol. 49, no. 1, e2021GL095184, Wiley, 2022, doi:<a href=\"https://doi.org/10.1029/2021GL095184\">10.1029/2021GL095184</a>.","apa":"Abramian, S., Muller, C. J., &#38; Risi, C. (2022). Shear-convection interactions and orientation of tropical squall lines. <i>Geophysical Research Letters</i>. Wiley. <a href=\"https://doi.org/10.1029/2021GL095184\">https://doi.org/10.1029/2021GL095184</a>","ama":"Abramian S, Muller CJ, Risi C. Shear-convection interactions and orientation of tropical squall lines. <i>Geophysical Research Letters</i>. 2022;49(1). doi:<a href=\"https://doi.org/10.1029/2021GL095184\">10.1029/2021GL095184</a>","short":"S. Abramian, C.J. Muller, C. Risi, Geophysical Research Letters 49 (2022).","ieee":"S. Abramian, C. J. Muller, and C. Risi, “Shear-convection interactions and orientation of tropical squall lines,” <i>Geophysical Research Letters</i>, vol. 49, no. 1. Wiley, 2022."},"month":"01","file":[{"relation":"main_file","checksum":"08f88b57b8e409b42e382452cd5f297b","success":1,"file_name":"2022_GeophysResearchLet_Abramian.pdf","access_level":"open_access","content_type":"application/pdf","file_id":"10662","file_size":1117408,"date_created":"2022-01-24T12:14:41Z","creator":"cchlebak","date_updated":"2022-01-24T12:14:41Z"}],"article_number":"e2021GL095184","department":[{"_id":"CaMu"}]},{"month":"01","arxiv":1,"department":[{"_id":"BjHo"}],"article_number":"014502","oa":1,"language":[{"iso":"eng"}],"issue":"1","citation":{"ama":"Klotz L, Lemoult GM, Avila K, Hof B. Phase transition to turbulence in spatially extended shear flows. <i>Physical Review Letters</i>. 2022;128(1). doi:<a href=\"https://doi.org/10.1103/PhysRevLett.128.014502\">10.1103/PhysRevLett.128.014502</a>","ieee":"L. Klotz, G. M. Lemoult, K. Avila, and B. Hof, “Phase transition to turbulence in spatially extended shear flows,” <i>Physical Review Letters</i>, vol. 128, no. 1. American Physical Society, 2022.","short":"L. Klotz, G.M. Lemoult, K. Avila, B. Hof, Physical Review Letters 128 (2022).","chicago":"Klotz, Lukasz, Grégoire M Lemoult, Kerstin Avila, and Björn Hof. “Phase Transition to Turbulence in Spatially Extended Shear Flows.” <i>Physical Review Letters</i>. American Physical Society, 2022. <a href=\"https://doi.org/10.1103/PhysRevLett.128.014502\">https://doi.org/10.1103/PhysRevLett.128.014502</a>.","ista":"Klotz L, Lemoult GM, Avila K, Hof B. 2022. Phase transition to turbulence in spatially extended shear flows. Physical Review Letters. 128(1), 014502.","apa":"Klotz, L., Lemoult, G. M., Avila, K., &#38; Hof, B. (2022). Phase transition to turbulence in spatially extended shear flows. <i>Physical Review Letters</i>. American Physical Society. <a href=\"https://doi.org/10.1103/PhysRevLett.128.014502\">https://doi.org/10.1103/PhysRevLett.128.014502</a>","mla":"Klotz, Lukasz, et al. “Phase Transition to Turbulence in Spatially Extended Shear Flows.” <i>Physical Review Letters</i>, vol. 128, no. 1, 014502, American Physical Society, 2022, doi:<a href=\"https://doi.org/10.1103/PhysRevLett.128.014502\">10.1103/PhysRevLett.128.014502</a>."},"user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","author":[{"first_name":"Lukasz","orcid":"0000-0003-1740-7635","id":"2C9AF1C2-F248-11E8-B48F-1D18A9856A87","full_name":"Klotz, Lukasz","last_name":"Klotz"},{"full_name":"Lemoult, Grégoire M","id":"4787FE80-F248-11E8-B48F-1D18A9856A87","last_name":"Lemoult","first_name":"Grégoire M"},{"last_name":"Avila","full_name":"Avila, Kerstin","first_name":"Kerstin"},{"last_name":"Hof","id":"3A374330-F248-11E8-B48F-1D18A9856A87","full_name":"Hof, Björn","first_name":"Björn","orcid":"0000-0003-2057-2754"}],"day":"05","scopus_import":"1","title":"Phase transition to turbulence in spatially extended shear flows","oa_version":"Preprint","volume":128,"article_type":"original","date_created":"2022-01-23T23:01:28Z","abstract":[{"lang":"eng","text":"Directed percolation (DP) has recently emerged as a possible solution to the century old puzzle surrounding the transition to turbulence. Multiple model studies reported DP exponents, however, experimental evidence is limited since the largest possible observation times are orders of magnitude shorter than the flows’ characteristic timescales. An exception is cylindrical Couette flow where the limit is not temporal, but rather the realizable system size. We present experiments in a Couette setup of unprecedented azimuthal and axial aspect ratios. Approaching the critical point to within less than 0.1% we determine five critical exponents, all of which are in excellent agreement with the 2+1D DP universality class. The complex dynamics encountered at \r\nthe onset of turbulence can hence be fully rationalized within the framework of statistical mechanics."}],"intvolume":"       128","acknowledged_ssus":[{"_id":"M-Shop"}],"publication_identifier":{"issn":["0031-9007"],"eissn":["1079-7114"]},"publication_status":"published","year":"2022","isi":1,"external_id":{"pmid":["35061458"],"arxiv":["2111.14894"],"isi":["000748271700010"]},"project":[{"grant_number":"754411","name":"ISTplus - Postdoctoral Fellowships","call_identifier":"H2020","_id":"260C2330-B435-11E9-9278-68D0E5697425"},{"call_identifier":"FP7","name":"Decoding the complexity of turbulence at its origin","grant_number":"306589","_id":"25152F3A-B435-11E9-9278-68D0E5697425"},{"_id":"238598C6-32DE-11EA-91FC-C7463DDC885E","name":"Revisiting the Turbulence Problem Using Statistical Mechanics: Experimental Studies on Transitional and Turbulent Flows","grant_number":"662960"}],"status":"public","publication":"Physical Review Letters","pmid":1,"ec_funded":1,"acknowledgement":"We thank T.Menner, T.Asenov, P. Maier and the Miba machine shop of IST Austria for their valuable support in all technical aspects. We thank Marc Avila for comments on the manuscript. This work was supported by a grant from the Simons Foundation (662960, B.H.). We acknowledge the European Research Council under the European Union’s Seventh Framework Programme (FP/2007-2013)/ERC Grant Agreement 306589 for financial support. K.A.\r\nacknowledges funding from the Central Research Development Fund of the University of Bremen, grant number ZF04B /2019/FB04 Avila Kerstin (”Independent Project for Postdocs”). L.K. was supported by the European Union’s Horizon 2020 Research and innovation programme under the Marie Sklodowska-Curie grant agreement  No. 754411.\r\n","date_published":"2022-01-05T00:00:00Z","doi":"10.1103/PhysRevLett.128.014502","article_processing_charge":"No","publisher":"American Physical Society","date_updated":"2023-08-02T13:59:19Z","_id":"10654","type":"journal_article","main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/2111.14894"}],"quality_controlled":"1"},{"main_file_link":[{"url":" https://doi.org/10.48550/arXiv.2208.03160","open_access":"1"}],"quality_controlled":"1","page":"350-365","date_updated":"2023-05-03T08:00:46Z","_id":"11839","type":"conference","doi":"10.1007/978-3-031-19803-8_21","article_processing_charge":"No","alternative_title":["LNCS"],"publisher":"Springer Nature","conference":{"location":"Tel Aviv, Israel","name":"ECCV: European Conference on Computer Vision","end_date":"2022-10-27","start_date":"2022-10-23"},"date_published":"2022-10-23T00:00:00Z","publication":"Computer Vision – ECCV 2022","status":"public","year":"2022","external_id":{"arxiv":["2208.03160"]},"publication_status":"published","publication_identifier":{"isbn":["9783031198021"],"eisbn":["9783031198038"]},"abstract":[{"lang":"eng","text":"It is a highly desirable property for deep networks to be robust against\r\nsmall input changes. One popular way to achieve this property is by designing\r\nnetworks with a small Lipschitz constant. In this work, we propose a new\r\ntechnique for constructing such Lipschitz networks that has a number of\r\ndesirable properties: it can be applied to any linear network layer\r\n(fully-connected or convolutional), it provides formal guarantees on the\r\nLipschitz constant, it is easy to implement and efficient to run, and it can be\r\ncombined with any training objective and optimization method. In fact, our\r\ntechnique is the first one in the literature that achieves all of these\r\nproperties simultaneously. Our main contribution is a rescaling-based weight\r\nmatrix parametrization that guarantees each network layer to have a Lipschitz\r\nconstant of at most 1 and results in the learned weight matrices to be close to\r\northogonal. Hence we call such layers almost-orthogonal Lipschitz (AOL).\r\nExperiments and ablation studies in the context of image classification with\r\ncertified robust accuracy confirm that AOL layers achieve results that are on\r\npar with most existing methods. Yet, they are simpler to implement and more\r\nbroadly applicable, because they do not require computationally expensive\r\nmatrix orthogonalization or inversion steps as part of the network\r\narchitecture. We provide code at https://github.com/berndprach/AOL."}],"intvolume":"     13681","volume":13681,"date_created":"2022-08-12T15:09:47Z","author":[{"first_name":"Bernd","last_name":"Prach","id":"2D561D42-C427-11E9-89B4-9C1AE6697425","full_name":"Prach, Bernd"},{"first_name":"Christoph","orcid":"0000-0001-8622-7887","id":"40C20FD2-F248-11E8-B48F-1D18A9856A87","full_name":"Lampert, Christoph","last_name":"Lampert"}],"day":"23","scopus_import":"1","title":"Almost-orthogonal layers for efficient general-purpose Lipschitz networks","oa_version":"Preprint","citation":{"mla":"Prach, Bernd, and Christoph Lampert. “Almost-Orthogonal Layers for Efficient General-Purpose Lipschitz Networks.” <i>Computer Vision – ECCV 2022</i>, vol. 13681, Springer Nature, 2022, pp. 350–65, doi:<a href=\"https://doi.org/10.1007/978-3-031-19803-8_21\">10.1007/978-3-031-19803-8_21</a>.","apa":"Prach, B., &#38; Lampert, C. (2022). Almost-orthogonal layers for efficient general-purpose Lipschitz networks. In <i>Computer Vision – ECCV 2022</i> (Vol. 13681, pp. 350–365). Tel Aviv, Israel: Springer Nature. <a href=\"https://doi.org/10.1007/978-3-031-19803-8_21\">https://doi.org/10.1007/978-3-031-19803-8_21</a>","ista":"Prach B, Lampert C. 2022. Almost-orthogonal layers for efficient general-purpose Lipschitz networks. Computer Vision – ECCV 2022. ECCV: European Conference on Computer Vision, LNCS, vol. 13681, 350–365.","chicago":"Prach, Bernd, and Christoph Lampert. “Almost-Orthogonal Layers for Efficient General-Purpose Lipschitz Networks.” In <i>Computer Vision – ECCV 2022</i>, 13681:350–65. Springer Nature, 2022. <a href=\"https://doi.org/10.1007/978-3-031-19803-8_21\">https://doi.org/10.1007/978-3-031-19803-8_21</a>.","short":"B. Prach, C. Lampert, in:, Computer Vision – ECCV 2022, Springer Nature, 2022, pp. 350–365.","ieee":"B. Prach and C. Lampert, “Almost-orthogonal layers for efficient general-purpose Lipschitz networks,” in <i>Computer Vision – ECCV 2022</i>, Tel Aviv, Israel, 2022, vol. 13681, pp. 350–365.","ama":"Prach B, Lampert C. Almost-orthogonal layers for efficient general-purpose Lipschitz networks. In: <i>Computer Vision – ECCV 2022</i>. Vol 13681. Springer Nature; 2022:350-365. doi:<a href=\"https://doi.org/10.1007/978-3-031-19803-8_21\">10.1007/978-3-031-19803-8_21</a>"},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa":1,"language":[{"iso":"eng"}],"department":[{"_id":"GradSch"},{"_id":"ChLa"}],"month":"10","arxiv":1},{"year":"2022","isi":1,"external_id":{"isi":["000903753500002"]},"ec_funded":1,"acknowledgement":"The research leading to these results has received funding from the European Research Council (ERC) under the European Union’s Seventh Framework Programme (FP7/2007-2013) through the ERC grant PhysProt\r\n(agreement 337969). We are grateful for financial support from the Biotechnology and Biological Sciences Research Council (BBSRC) (T.P.J.K.), the Newman\r\nFoundation (T.P.J.K.), the Wellcome Trust (T.P.J.K. and M.V.), Peterhouse College\r\nCambridge (T.C.T.M.), the ERC Starting Grant (StG) Non-Equilibrium Protein Assembly (NEPA) (A.S.), the Royal Society (A.S.), the Academy of Medical Sciences\r\n(A.S. and J.K.), and the Cambridge Centre for Misfolding Diseases (CMD).","date_published":"2022-07-28T00:00:00Z","project":[{"_id":"eba2549b-77a9-11ec-83b8-a81e493eae4e","call_identifier":"H2020","grant_number":"802960","name":"Non-Equilibrium Protein Assembly: from Building Blocks to Biological Machines"}],"status":"public","publication":"Proceedings of the National Academy of Sciences of the United States of America","date_updated":"2023-10-04T09:06:52Z","_id":"11841","type":"journal_article","doi":"10.1073/pnas.2109718119","article_processing_charge":"No","publisher":"Proceedings of the National Academy of Sciences","quality_controlled":"1","ddc":["570"],"department":[{"_id":"AnSa"}],"file":[{"file_id":"14386","file_size":2476021,"date_created":"2023-10-04T09:05:44Z","date_updated":"2023-10-04T09:05:44Z","creator":"dernst","relation":"main_file","checksum":"0fe3878896cbeb6c44e29222ec2f336a","file_name":"2022_PNAS_Toprakcioglu.pdf","success":1,"content_type":"application/pdf","access_level":"open_access"}],"article_number":"e2109718119","month":"07","issue":"31","citation":{"ama":"Toprakcioglu Z, Kamada A, Michaels TCT, et al. Adsorption free energy predicts amyloid protein nucleation rates. <i>Proceedings of the National Academy of Sciences of the United States of America</i>. 2022;119(31). doi:<a href=\"https://doi.org/10.1073/pnas.2109718119\">10.1073/pnas.2109718119</a>","ieee":"Z. Toprakcioglu <i>et al.</i>, “Adsorption free energy predicts amyloid protein nucleation rates,” <i>Proceedings of the National Academy of Sciences of the United States of America</i>, vol. 119, no. 31. Proceedings of the National Academy of Sciences, 2022.","short":"Z. Toprakcioglu, A. Kamada, T.C.T. Michaels, M. Xie, J. Krausser, J. Wei, A. Šarić, M. Vendruscolo, T.P.J. Knowles, Proceedings of the National Academy of Sciences of the United States of America 119 (2022).","chicago":"Toprakcioglu, Zenon, Ayaka Kamada, Thomas C.T. Michaels, Mengqi Xie, Johannes Krausser, Jiapeng Wei, Anđela Šarić, Michele Vendruscolo, and Tuomas P.J. Knowles. “Adsorption Free Energy Predicts Amyloid Protein Nucleation Rates.” <i>Proceedings of the National Academy of Sciences of the United States of America</i>. Proceedings of the National Academy of Sciences, 2022. <a href=\"https://doi.org/10.1073/pnas.2109718119\">https://doi.org/10.1073/pnas.2109718119</a>.","ista":"Toprakcioglu Z, Kamada A, Michaels TCT, Xie M, Krausser J, Wei J, Šarić A, Vendruscolo M, Knowles TPJ. 2022. Adsorption free energy predicts amyloid protein nucleation rates. Proceedings of the National Academy of Sciences of the United States of America. 119(31), e2109718119.","apa":"Toprakcioglu, Z., Kamada, A., Michaels, T. C. T., Xie, M., Krausser, J., Wei, J., … Knowles, T. P. J. (2022). Adsorption free energy predicts amyloid protein nucleation rates. <i>Proceedings of the National Academy of Sciences of the United States of America</i>. Proceedings of the National Academy of Sciences. <a href=\"https://doi.org/10.1073/pnas.2109718119\">https://doi.org/10.1073/pnas.2109718119</a>","mla":"Toprakcioglu, Zenon, et al. “Adsorption Free Energy Predicts Amyloid Protein Nucleation Rates.” <i>Proceedings of the National Academy of Sciences of the United States of America</i>, vol. 119, no. 31, e2109718119, Proceedings of the National Academy of Sciences, 2022, doi:<a href=\"https://doi.org/10.1073/pnas.2109718119\">10.1073/pnas.2109718119</a>."},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa":1,"language":[{"iso":"eng"}],"volume":119,"article_type":"original","date_created":"2022-08-14T22:01:45Z","author":[{"last_name":"Toprakcioglu","full_name":"Toprakcioglu, Zenon","first_name":"Zenon"},{"last_name":"Kamada","full_name":"Kamada, Ayaka","first_name":"Ayaka"},{"last_name":"Michaels","full_name":"Michaels, Thomas C.T.","first_name":"Thomas C.T."},{"last_name":"Xie","full_name":"Xie, Mengqi","first_name":"Mengqi"},{"first_name":"Johannes","last_name":"Krausser","full_name":"Krausser, Johannes"},{"first_name":"Jiapeng","last_name":"Wei","full_name":"Wei, Jiapeng"},{"last_name":"Šarić","id":"bf63d406-f056-11eb-b41d-f263a6566d8b","full_name":"Šarić, Anđela","orcid":"0000-0002-7854-2139","first_name":"Anđela"},{"first_name":"Michele","last_name":"Vendruscolo","full_name":"Vendruscolo, Michele"},{"last_name":"Knowles","full_name":"Knowles, Tuomas P.J.","first_name":"Tuomas P.J."}],"scopus_import":"1","day":"28","oa_version":"Published Version","title":"Adsorption free energy predicts amyloid protein nucleation rates","publication_identifier":{"eissn":["1091-6490"],"issn":["0027-8424"]},"publication_status":"published","file_date_updated":"2023-10-04T09:05:44Z","has_accepted_license":"1","license":"https://creativecommons.org/licenses/by-nc-nd/4.0/","tmp":{"image":"/images/cc_by_nc_nd.png","name":"Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode","short":"CC BY-NC-ND (4.0)"},"intvolume":"       119","abstract":[{"text":"Primary nucleation is the fundamental event that initiates the conversion of proteins from their normal physiological forms into pathological amyloid aggregates associated with the onset and development of disorders including systemic amyloidosis, as well as the neurodegenerative conditions Alzheimer’s and Parkinson’s diseases. It has become apparent that the presence of surfaces can dramatically modulate nucleation. However, the underlying physicochemical parameters governing this process have been challenging to elucidate, with interfaces in some cases having been found to accelerate aggregation, while in others they can inhibit the kinetics of this process. Here we show through kinetic analysis that for three different fibril-forming proteins, interfaces affect the aggregation reaction mainly through modulating the primary nucleation step. Moreover, we show through direct measurements of the Gibbs free energy of adsorption, combined with theory and coarse-grained computer simulations, that overall nucleation rates are suppressed at high and at low surface interaction strengths but significantly enhanced at intermediate strengths, and we verify these regimes experimentally. Taken together, these results provide a quantitative description of the fundamental process which triggers amyloid formation and shed light on the key factors that control this process.","lang":"eng"}]},{"file":[{"file_id":"11848","date_created":"2022-08-16T06:55:22Z","file_size":2045570,"creator":"cchlebak","date_updated":"2022-08-16T06:55:22Z","relation":"main_file","checksum":"75c5f286300e6f0539cf57b4dba108d5","file_name":"2022_JMathFluidMech_Hensel.pdf","success":1,"content_type":"application/pdf","access_level":"open_access"}],"article_number":"93","department":[{"_id":"JuFi"}],"arxiv":1,"month":"08","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","issue":"3","citation":{"apa":"Hensel, S., &#38; Marveggio, A. (2022). Weak-strong uniqueness for the Navier–Stokes equation for two fluids with ninety degree contact angle and same viscosities. <i>Journal of Mathematical Fluid Mechanics</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s00021-022-00722-2\">https://doi.org/10.1007/s00021-022-00722-2</a>","mla":"Hensel, Sebastian, and Alice Marveggio. “Weak-Strong Uniqueness for the Navier–Stokes Equation for Two Fluids with Ninety Degree Contact Angle and Same Viscosities.” <i>Journal of Mathematical Fluid Mechanics</i>, vol. 24, no. 3, 93, Springer Nature, 2022, doi:<a href=\"https://doi.org/10.1007/s00021-022-00722-2\">10.1007/s00021-022-00722-2</a>.","chicago":"Hensel, Sebastian, and Alice Marveggio. “Weak-Strong Uniqueness for the Navier–Stokes Equation for Two Fluids with Ninety Degree Contact Angle and Same Viscosities.” <i>Journal of Mathematical Fluid Mechanics</i>. Springer Nature, 2022. <a href=\"https://doi.org/10.1007/s00021-022-00722-2\">https://doi.org/10.1007/s00021-022-00722-2</a>.","ista":"Hensel S, Marveggio A. 2022. Weak-strong uniqueness for the Navier–Stokes equation for two fluids with ninety degree contact angle and same viscosities. Journal of Mathematical Fluid Mechanics. 24(3), 93.","ieee":"S. Hensel and A. Marveggio, “Weak-strong uniqueness for the Navier–Stokes equation for two fluids with ninety degree contact angle and same viscosities,” <i>Journal of Mathematical Fluid Mechanics</i>, vol. 24, no. 3. Springer Nature, 2022.","short":"S. Hensel, A. Marveggio, Journal of Mathematical Fluid Mechanics 24 (2022).","ama":"Hensel S, Marveggio A. Weak-strong uniqueness for the Navier–Stokes equation for two fluids with ninety degree contact angle and same viscosities. <i>Journal of Mathematical Fluid Mechanics</i>. 2022;24(3). doi:<a href=\"https://doi.org/10.1007/s00021-022-00722-2\">10.1007/s00021-022-00722-2</a>"},"language":[{"iso":"eng"}],"oa":1,"article_type":"original","date_created":"2022-08-14T22:01:45Z","volume":24,"oa_version":"Published Version","title":"Weak-strong uniqueness for the Navier–Stokes equation for two fluids with ninety degree contact angle and same viscosities","author":[{"orcid":"0000-0001-7252-8072","first_name":"Sebastian","last_name":"Hensel","id":"4D23B7DA-F248-11E8-B48F-1D18A9856A87","full_name":"Hensel, Sebastian"},{"first_name":"Alice","id":"25647992-AA84-11E9-9D75-8427E6697425","full_name":"Marveggio, Alice","last_name":"Marveggio"}],"day":"01","scopus_import":"1","publication_identifier":{"issn":["1422-6928"],"eissn":["1422-6952"]},"publication_status":"published","file_date_updated":"2022-08-16T06:55:22Z","intvolume":"        24","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","short":"CC BY (4.0)"},"abstract":[{"lang":"eng","text":"We consider the flow of two viscous and incompressible fluids within a bounded domain modeled by means of a two-phase Navier–Stokes system. The two fluids are assumed to be immiscible, meaning that they are separated by an interface. With respect to the motion of the interface, we consider pure transport by the fluid flow. Along the boundary of the domain, a complete slip boundary condition for the fluid velocities and a constant ninety degree contact angle condition for the interface are assumed. In the present work, we devise for the resulting evolution problem a suitable weak solution concept based on the framework of varifolds and establish as the main result a weak-strong uniqueness principle in 2D. The proof is based on a relative entropy argument and requires a non-trivial further development of ideas from the recent work of Fischer and the first author (Arch. Ration. Mech. Anal. 236, 2020) to incorporate the contact angle condition. To focus on the effects of the necessarily singular geometry of the evolving fluid domains, we work for simplicity in the regime of same viscosities for the two fluids."}],"has_accepted_license":"1","external_id":{"isi":["000834834300001"],"arxiv":["2112.11154"]},"related_material":{"record":[{"relation":"dissertation_contains","status":"public","id":"14587"}]},"isi":1,"year":"2022","date_published":"2022-08-01T00:00:00Z","acknowledgement":"The authors warmly thank their former resp. current PhD advisor Julian Fischer for the suggestion of this problem and for valuable initial discussions on the subjects of this paper. This project has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement No 948819) , and from the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germany’s Excellence Strategy – EXC-2047/1 – 390685813.","ec_funded":1,"project":[{"call_identifier":"H2020","name":"Bridging Scales in Random Materials","grant_number":"948819","_id":"0aa76401-070f-11eb-9043-b5bb049fa26d"}],"publication":"Journal of Mathematical Fluid Mechanics","status":"public","type":"journal_article","date_updated":"2023-11-30T13:25:02Z","_id":"11842","publisher":"Springer Nature","doi":"10.1007/s00021-022-00722-2","article_processing_charge":"No","quality_controlled":"1","ddc":["510"]},{"quality_controlled":"1","ddc":["570"],"_id":"11843","date_updated":"2023-08-03T12:54:21Z","type":"journal_article","article_processing_charge":"Yes","doi":"10.7554/eLife.78995","publisher":"eLife Sciences Publications","ec_funded":1,"date_published":"2022-07-26T00:00:00Z","acknowledgement":"We thank Ulrich Dobrindt for providing UPEC strains CFT073, UTI89, and 536, Frank Assen, Vlad Gavra, Maximilian Götz, Bor Kavčič, Jonna Alanko, and Eva Kiermaier for help with experiments and Robert Hauschild, Julian Stopp, and Saren Tasciyan for help with data analysis. We thank the IST Austria Scientific Service Units, especially the Bioimaging facility, the Preclinical facility and the Electron microscopy facility for technical support, Jakob Wallner and all members of the Guet and Sixt lab for fruitful discussions and Daria Siekhaus for critically reading the manuscript. This work was supported by grants from the Austrian Research Promotion Agency (FEMtech 868984) to IG, the European Research Council (CoG 724373), and the Austrian Science Fund (FWF P29911) to MS.","status":"public","publication":"eLife","project":[{"call_identifier":"H2020","name":"Cellular navigation along spatial gradients","grant_number":"724373","_id":"25FE9508-B435-11E9-9278-68D0E5697425"},{"_id":"26018E70-B435-11E9-9278-68D0E5697425","call_identifier":"FWF","name":"Mechanical adaptation of lamellipodial actin","grant_number":"P29911"}],"year":"2022","isi":1,"related_material":{"record":[{"id":"10316","relation":"earlier_version","status":"public"}]},"external_id":{"isi":["000838410200001"]},"file_date_updated":"2022-08-16T08:57:37Z","publication_identifier":{"eissn":["2050-084X"]},"publication_status":"published","has_accepted_license":"1","acknowledged_ssus":[{"_id":"Bio"},{"_id":"PreCl"},{"_id":"EM-Fac"}],"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","short":"CC BY (4.0)"},"intvolume":"        11","abstract":[{"text":"A key attribute of persistent or recurring bacterial infections is the ability of the pathogen to evade the host’s immune response. Many Enterobacteriaceae express type 1 pili, a pre-adapted virulence trait, to invade host epithelial cells and establish persistent infections. However, the molecular mechanisms and strategies by which bacteria actively circumvent the immune response of the host remain poorly understood. Here, we identified CD14, the major co-receptor for lipopolysaccharide detection, on mouse dendritic cells (DCs) as a binding partner of FimH, the protein located at the tip of the type 1 pilus of Escherichia coli. The FimH amino acids involved in CD14 binding are highly conserved across pathogenic and non-pathogenic strains. Binding of the pathogenic strain CFT073 to CD14 reduced DC migration by overactivation of integrins and blunted expression of co-stimulatory molecules by overactivating the NFAT (nuclear factor of activated T-cells) pathway, both rate-limiting factors of T cell activation. This response was binary at the single-cell level, but averaged in larger populations exposed to both piliated and non-piliated pathogens, presumably via the exchange of immunomodulatory cytokines. While defining an active molecular mechanism of immune evasion by pathogens, the interaction between FimH and CD14 represents a potential target to interfere with persistent and recurrent infections, such as urinary tract infections or Crohn’s disease.","lang":"eng"}],"volume":11,"date_created":"2022-08-14T22:01:46Z","article_type":"original","scopus_import":"1","day":"26","author":[{"id":"3AEC8556-F248-11E8-B48F-1D18A9856A87","full_name":"Tomasek, Kathrin","last_name":"Tomasek","first_name":"Kathrin"},{"full_name":"Leithner, Alexander F","id":"3B1B77E4-F248-11E8-B48F-1D18A9856A87","last_name":"Leithner","first_name":"Alexander F"},{"first_name":"Ivana","last_name":"Glatzová","id":"727b3c7d-4939-11ec-89b3-b9b0750ab74d","full_name":"Glatzová, Ivana"},{"first_name":"Michael S.","full_name":"Lukesch, Michael S.","last_name":"Lukesch"},{"last_name":"Guet","full_name":"Guet, Calin C","id":"47F8433E-F248-11E8-B48F-1D18A9856A87","first_name":"Calin C","orcid":"0000-0001-6220-2052"},{"first_name":"Michael K","orcid":"0000-0002-6620-9179","last_name":"Sixt","full_name":"Sixt, Michael K","id":"41E9FBEA-F248-11E8-B48F-1D18A9856A87"}],"title":"Type 1 piliated uropathogenic Escherichia coli hijack the host immune response by binding to CD14","oa_version":"Published Version","citation":{"ista":"Tomasek K, Leithner AF, Glatzová I, Lukesch MS, Guet CC, Sixt MK. 2022. Type 1 piliated uropathogenic Escherichia coli hijack the host immune response by binding to CD14. eLife. 11, e78995.","chicago":"Tomasek, Kathrin, Alexander F Leithner, Ivana Glatzová, Michael S. Lukesch, Calin C Guet, and Michael K Sixt. “Type 1 Piliated Uropathogenic Escherichia Coli Hijack the Host Immune Response by Binding to CD14.” <i>ELife</i>. eLife Sciences Publications, 2022. <a href=\"https://doi.org/10.7554/eLife.78995\">https://doi.org/10.7554/eLife.78995</a>.","apa":"Tomasek, K., Leithner, A. F., Glatzová, I., Lukesch, M. S., Guet, C. C., &#38; Sixt, M. K. (2022). Type 1 piliated uropathogenic Escherichia coli hijack the host immune response by binding to CD14. <i>ELife</i>. eLife Sciences Publications. <a href=\"https://doi.org/10.7554/eLife.78995\">https://doi.org/10.7554/eLife.78995</a>","mla":"Tomasek, Kathrin, et al. “Type 1 Piliated Uropathogenic Escherichia Coli Hijack the Host Immune Response by Binding to CD14.” <i>ELife</i>, vol. 11, e78995, eLife Sciences Publications, 2022, doi:<a href=\"https://doi.org/10.7554/eLife.78995\">10.7554/eLife.78995</a>.","ama":"Tomasek K, Leithner AF, Glatzová I, Lukesch MS, Guet CC, Sixt MK. Type 1 piliated uropathogenic Escherichia coli hijack the host immune response by binding to CD14. <i>eLife</i>. 2022;11. doi:<a href=\"https://doi.org/10.7554/eLife.78995\">10.7554/eLife.78995</a>","ieee":"K. Tomasek, A. F. Leithner, I. Glatzová, M. S. Lukesch, C. C. Guet, and M. K. Sixt, “Type 1 piliated uropathogenic Escherichia coli hijack the host immune response by binding to CD14,” <i>eLife</i>, vol. 11. eLife Sciences Publications, 2022.","short":"K. Tomasek, A.F. Leithner, I. Glatzová, M.S. Lukesch, C.C. Guet, M.K. Sixt, ELife 11 (2022)."},"user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","oa":1,"language":[{"iso":"eng"}],"department":[{"_id":"MiSi"},{"_id":"CaGu"}],"file":[{"relation":"main_file","checksum":"002a3c7c7ea5caa9af9cfbea308f6ea4","success":1,"file_name":"2022_eLife_Tomasek.pdf","access_level":"open_access","content_type":"application/pdf","file_id":"11861","date_created":"2022-08-16T08:57:37Z","file_size":2057577,"date_updated":"2022-08-16T08:57:37Z","creator":"cchlebak"}],"article_number":"e78995","month":"07"},{"file_date_updated":"2022-08-16T08:05:15Z","publication_identifier":{"isbn":["9781450392624"]},"publication_status":"published","abstract":[{"text":"In the stochastic population protocol model, we are given a connected graph with n nodes, and in every time step, a scheduler samples an edge of the graph uniformly at random and the nodes connected by this edge interact. A fundamental task in this model is stable leader election, in which all nodes start in an identical state and the aim is to reach a configuration in which (1) exactly one node is elected as leader and (2) this node remains as the unique leader no matter what sequence of interactions follows. On cliques, the complexity of this problem has recently been settled: time-optimal protocols stabilize in Θ(n log n) expected steps using Θ(log log n) states, whereas protocols that use O(1) states require Θ(n2) expected steps.\r\n\r\nIn this work, we investigate the complexity of stable leader election on general graphs. We provide the first non-trivial time lower bounds for leader election on general graphs, showing that, when moving beyond cliques, the complexity landscape of leader election becomes very diverse: the time required to elect a leader can range from O(1) to Θ(n3) expected steps. On the upper bound side, we first observe that there exists a protocol that is time-optimal on many graph families, but uses polynomially-many states. In contrast, we give a near-time-optimal protocol that uses only O(log2n) states that is at most a factor log n slower. Finally, we show that the constant-state protocol of Beauquier et al. [OPODIS 2013] is at most a factor n log n slower than the fast polynomial-state protocol. Moreover, among constant-state protocols, this protocol has near-optimal average case complexity on dense random graphs.","lang":"eng"}],"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","short":"CC BY (4.0)"},"has_accepted_license":"1","date_created":"2022-08-14T22:01:46Z","title":"Near-optimal leader election in population protocols on graphs","oa_version":"Published Version","day":"21","scopus_import":"1","author":[{"last_name":"Alistarh","id":"4A899BFC-F248-11E8-B48F-1D18A9856A87","full_name":"Alistarh, Dan-Adrian","orcid":"0000-0003-3650-940X","first_name":"Dan-Adrian"},{"orcid":"0000-0002-6432-6646","first_name":"Joel","id":"334EFD2E-F248-11E8-B48F-1D18A9856A87","full_name":"Rybicki, Joel","last_name":"Rybicki"},{"first_name":"Sasha","full_name":"Voitovych, Sasha","last_name":"Voitovych"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","citation":{"ama":"Alistarh D-A, Rybicki J, Voitovych S. Near-optimal leader election in population protocols on graphs. In: <i>Proceedings of the Annual ACM Symposium on Principles of Distributed Computing</i>. Association for Computing Machinery; 2022:246-256. doi:<a href=\"https://doi.org/10.1145/3519270.3538435\">10.1145/3519270.3538435</a>","short":"D.-A. Alistarh, J. Rybicki, S. Voitovych, in:, Proceedings of the Annual ACM Symposium on Principles of Distributed Computing, Association for Computing Machinery, 2022, pp. 246–256.","ieee":"D.-A. Alistarh, J. Rybicki, and S. Voitovych, “Near-optimal leader election in population protocols on graphs,” in <i>Proceedings of the Annual ACM Symposium on Principles of Distributed Computing</i>, Salerno, Italy, 2022, pp. 246–256.","chicago":"Alistarh, Dan-Adrian, Joel Rybicki, and Sasha Voitovych. “Near-Optimal Leader Election in Population Protocols on Graphs.” In <i>Proceedings of the Annual ACM Symposium on Principles of Distributed Computing</i>, 246–56. Association for Computing Machinery, 2022. <a href=\"https://doi.org/10.1145/3519270.3538435\">https://doi.org/10.1145/3519270.3538435</a>.","ista":"Alistarh D-A, Rybicki J, Voitovych S. 2022. Near-optimal leader election in population protocols on graphs. Proceedings of the Annual ACM Symposium on Principles of Distributed Computing. PODC: Symposium on Principles of Distributed Computing, 246–256.","mla":"Alistarh, Dan-Adrian, et al. “Near-Optimal Leader Election in Population Protocols on Graphs.” <i>Proceedings of the Annual ACM Symposium on Principles of Distributed Computing</i>, Association for Computing Machinery, 2022, pp. 246–56, doi:<a href=\"https://doi.org/10.1145/3519270.3538435\">10.1145/3519270.3538435</a>.","apa":"Alistarh, D.-A., Rybicki, J., &#38; Voitovych, S. (2022). Near-optimal leader election in population protocols on graphs. In <i>Proceedings of the Annual ACM Symposium on Principles of Distributed Computing</i> (pp. 246–256). Salerno, Italy: Association for Computing Machinery. <a href=\"https://doi.org/10.1145/3519270.3538435\">https://doi.org/10.1145/3519270.3538435</a>"},"language":[{"iso":"eng"}],"oa":1,"file":[{"date_created":"2022-08-16T08:05:15Z","file_size":1593474,"date_updated":"2022-08-16T08:05:15Z","creator":"cchlebak","file_id":"11854","file_name":"2022_PODC_Alistarh.pdf","success":1,"content_type":"application/pdf","access_level":"open_access","relation":"main_file","checksum":"4c6b29172b8e355b4fbc364a2e0827b2"}],"department":[{"_id":"DaAl"}],"month":"07","arxiv":1,"quality_controlled":"1","ddc":["000"],"page":"246-256","type":"conference","_id":"11844","date_updated":"2023-06-14T12:06:01Z","publisher":"Association for Computing Machinery","article_processing_charge":"Yes (via OA deal)","doi":"10.1145/3519270.3538435","date_published":"2022-07-21T00:00:00Z","acknowledgement":"We thank the anonymous reviewers for their helpful comments. We gratefully acknowledge funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement No 805223 ScaleML).","conference":{"name":"PODC: Symposium on Principles of Distributed Computing","start_date":"2022-07-25","end_date":"2022-07-29","location":"Salerno, Italy"},"ec_funded":1,"publication":"Proceedings of the Annual ACM Symposium on Principles of Distributed Computing","status":"public","project":[{"_id":"268A44D6-B435-11E9-9278-68D0E5697425","grant_number":"805223","name":"Elastic Coordination for Scalable Machine Learning","call_identifier":"H2020"}],"external_id":{"arxiv":["2205.12597"]},"year":"2022"},{"oa":1,"language":[{"iso":"eng"}],"issue":"2","citation":{"chicago":"Agresti, Antonio, and Mark Veraar. “Nonlinear Parabolic Stochastic Evolution Equations in Critical Spaces Part II.” <i>Journal of Evolution Equations</i>. Springer Nature, 2022. <a href=\"https://doi.org/10.1007/s00028-022-00786-7\">https://doi.org/10.1007/s00028-022-00786-7</a>.","ista":"Agresti A, Veraar M. 2022. Nonlinear parabolic stochastic evolution equations in critical spaces part II. Journal of Evolution Equations. 22(2), 56.","mla":"Agresti, Antonio, and Mark Veraar. “Nonlinear Parabolic Stochastic Evolution Equations in Critical Spaces Part II.” <i>Journal of Evolution Equations</i>, vol. 22, no. 2, 56, Springer Nature, 2022, doi:<a href=\"https://doi.org/10.1007/s00028-022-00786-7\">10.1007/s00028-022-00786-7</a>.","apa":"Agresti, A., &#38; Veraar, M. (2022). Nonlinear parabolic stochastic evolution equations in critical spaces part II. <i>Journal of Evolution Equations</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s00028-022-00786-7\">https://doi.org/10.1007/s00028-022-00786-7</a>","ama":"Agresti A, Veraar M. Nonlinear parabolic stochastic evolution equations in critical spaces part II. <i>Journal of Evolution Equations</i>. 2022;22(2). doi:<a href=\"https://doi.org/10.1007/s00028-022-00786-7\">10.1007/s00028-022-00786-7</a>","short":"A. Agresti, M. Veraar, Journal of Evolution Equations 22 (2022).","ieee":"A. Agresti and M. Veraar, “Nonlinear parabolic stochastic evolution equations in critical spaces part II,” <i>Journal of Evolution Equations</i>, vol. 22, no. 2. Springer Nature, 2022."},"user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","month":"06","department":[{"_id":"JuFi"}],"article_number":"56","file":[{"date_created":"2022-08-16T08:52:46Z","file_size":1758371,"date_updated":"2022-08-16T08:52:46Z","creator":"kschuh","file_id":"11862","success":1,"file_name":"2022_Journal of Evolution Equations_Agresti.pdf","access_level":"open_access","content_type":"application/pdf","relation":"main_file","checksum":"59b99d1b48b6bd40983e7ce298524a21"}],"has_accepted_license":"1","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","short":"CC BY (4.0)"},"intvolume":"        22","abstract":[{"text":"This paper is a continuation of Part I of this project, where we developed a new local well-posedness theory for nonlinear stochastic PDEs with Gaussian noise. In the current Part II we consider blow-up criteria and regularization phenomena. As in Part I we can allow nonlinearities with polynomial growth and rough initial values from critical spaces. In the first main result we obtain several new blow-up criteria for quasi- and semilinear stochastic evolution equations. In particular, for semilinear equations we obtain a Serrin type blow-up criterium, which extends a recent result of Prüss–Simonett–Wilke (J Differ Equ 264(3):2028–2074, 2018) to the stochastic setting. Blow-up criteria can be used to prove global well-posedness for SPDEs. As in Part I, maximal regularity techniques and weights in time play a central role in the proofs. Our second contribution is a new method to bootstrap Sobolev and Hölder regularity in time and space, which does not require smoothness of the initial data. The blow-up criteria are at the basis of these new methods. Moreover, in applications the bootstrap results can be combined with our blow-up criteria, to obtain efficient ways to prove global existence. This gives new results even in classical 𝐿2-settings, which we illustrate for a concrete SPDE. In future works in preparation we apply the results of the current paper to obtain global well-posedness results and regularity for several concrete SPDEs. These include stochastic Navier–Stokes equations, reaction– diffusion equations and the Allen–Cahn equation. Our setting allows to put these SPDEs into a more flexible framework, where less restrictions on the nonlinearities are needed, and we are able to treat rough initial values from critical spaces. Moreover, we will obtain higher-order regularity results.","lang":"eng"}],"publication_status":"published","publication_identifier":{"issn":["1424-3199"],"eissn":["1424-3202"]},"file_date_updated":"2022-08-16T08:52:46Z","author":[{"orcid":"0000-0002-9573-2962","first_name":"Antonio","id":"673cd0cc-9b9a-11eb-b144-88f30e1fbb72","full_name":"Agresti, Antonio","last_name":"Agresti"},{"first_name":"Mark","full_name":"Veraar, Mark","last_name":"Veraar"}],"scopus_import":"1","day":"01","oa_version":"Published Version","title":"Nonlinear parabolic stochastic evolution equations in critical spaces part II","volume":22,"article_type":"original","date_created":"2022-08-16T08:39:43Z","publication":"Journal of Evolution Equations","status":"public","acknowledgement":"The authors thank Emiel Lorist for helpful comments. The authors thank the anonymous referees for their helpful remarks to improve the presentation.\r\nOpen access funding provided by Institute of Science and Technology (IST Austria).","date_published":"2022-06-01T00:00:00Z","year":"2022","isi":1,"external_id":{"isi":["000809108500001"]},"keyword":["Mathematics (miscellaneous)"],"ddc":["510"],"quality_controlled":"1","doi":"10.1007/s00028-022-00786-7","article_processing_charge":"Yes (via OA deal)","publisher":"Springer Nature","date_updated":"2023-08-03T12:53:51Z","_id":"11858","type":"journal_article"},{"publisher":"Institute of Science and Technology Austria","article_processing_charge":"No","alternative_title":["ISTA Thesis"],"doi":"10.15479/at:ista:11879","type":"dissertation","_id":"11879","date_updated":"2023-09-09T22:30:04Z","ddc":["580"],"page":"128","year":"2022","keyword":["high ambient temperature","auxin","PINs","Zinc-Finger proteins","thermomorphogenesis","stress"],"status":"public","project":[{"name":"Hormonal regulation of plant adaptive responses to environmental signals","_id":"2685A872-B435-11E9-9278-68D0E5697425"}],"degree_awarded":"PhD","date_published":"2022-08-17T00:00:00Z","acknowledgement":"I would like to acknowledge ISTA and all the people from the Scientific Service Units and at ISTA, in particular Dorota Jaworska for excellent technical and scientific support as well as ÖAW for funding my research for over 3 years (DOC ÖAW Fellowship PR1022OEAW02).","oa_version":"Published Version","title":"Modulation of auxin transport via ZF proteins adjust plant response to high ambient temperature","day":"17","author":[{"id":"45DF286A-F248-11E8-B48F-1D18A9856A87","full_name":"Artner, Christina","last_name":"Artner","first_name":"Christina"}],"date_created":"2022-08-17T07:58:53Z","acknowledged_ssus":[{"_id":"Bio"},{"_id":"LifeSc"},{"_id":"SSU"}],"abstract":[{"lang":"eng","text":"As the overall global mean surface temperature is increasing due to climate change, plant\r\nadaptation to those stressful conditions is of utmost importance for their survival. Plants are\r\nsessile organisms, thus to compensate for their lack of mobility, they evolved a variety of\r\nmechanisms enabling them to flexibly adjust their physiological, growth and developmental\r\nprocesses to fluctuating temperatures and to survive in harsh environments. While these unique\r\nadaptation abilities provide an important evolutionary advantage, overall modulation of plant\r\ngrowth and developmental program due to non-optimal temperature negatively affects biomass\r\nproduction, crop productivity or sensitivity to pathogens. Thus, understanding molecular\r\nprocesses underlying plant adaptation to increased temperature can provide important\r\nresources for breeding strategies to ensure sufficient agricultural food production.\r\nAn increase in ambient temperature by a few degrees leads to profound changes in organ growth\r\nincluding enhanced hypocotyl elongation, expansion of petioles, hyponastic growth of leaves and\r\ncotyledons, collectively named thermomorphogenesis (Casal & Balasubramanian, 2019). Auxin,\r\none of the best-studied growth hormones, plays an essential role in this process by direct\r\nactivation of transcriptional and non-transcriptional processes resulting in elongation growth\r\n(Majda & Robert, 2018).To modulate hypocotyl growth in response to high ambient temperature\r\n(hAT), auxin needs to be redistributed accordingly. PINs, auxin efflux transporters, are key\r\ncomponents of the polar auxin transport (PAT) machinery, which controls the amount and\r\ndirection of auxin translocated in the plant tissues and organs(Adamowski & Friml, 2015). Hence,\r\nPIN-mediated transport is tightly linked with thermo-morphogenesis, and interference with PAT\r\nthrough either chemical or genetic means dramatically affecting the adaptive responses to hAT.\r\nIntriguingly, despite the key role of PIN mediated transport in growth response to hAT, whether\r\nand how PINs at the level of expression adapt to fluctuation in temperature is scarcely\r\nunderstood.\r\nWith genetic, molecular and advanced bio-imaging approaches, we demonstrate the role of PIN\r\nauxin transporters in the regulation of hypocotyl growth in response to hAT. We show that via\r\nadjustment of PIN3, PIN4 and PIN7 expression in cotyledons and hypocotyls, auxin distribution is modulated thereby determining elongation pattern of epidermal cells at hAT. Furthermore, we\r\nidentified three Zinc-Finger (ZF) transcription factors as novel molecular components of the\r\nthermo-regulatory network, which through negative regulation of PIN transcription adjust the\r\ntransport of auxin at hAT. Our results suggest that the ZF-PIN module might be a part of the\r\nnegative feedback loop attenuating the activity of the thermo-sensing pathway to restrain\r\nexaggerated growth and developmental responses to hAT."}],"has_accepted_license":"1","file_date_updated":"2023-09-09T22:30:03Z","publication_identifier":{"isbn":["978-3-99078-022-0"],"issn":["2663-337X"]},"publication_status":"published","month":"08","supervisor":[{"first_name":"Eva","orcid":"0000-0002-8510-9739","full_name":"Benková, Eva","id":"38F4F166-F248-11E8-B48F-1D18A9856A87","last_name":"Benková"}],"file":[{"file_id":"11907","file_size":11113608,"date_created":"2022-08-17T12:08:49Z","date_updated":"2023-09-09T22:30:03Z","embargo":"2023-09-08","creator":"cartner","relation":"main_file","checksum":"a2c2fdc28002538840490bfa6a08b2cb","file_name":"ChristinaArtner_PhD_Thesis_2022.pdf","access_level":"open_access","content_type":"application/pdf"},{"access_level":"closed","content_type":"application/octet-stream","file_name":"ChristinaArtner_PhD_Thesis_2022.7z","checksum":"66b461c074b815fbe63481b3f46a9f43","relation":"source_file","date_updated":"2023-09-09T22:30:03Z","creator":"cartner","date_created":"2022-08-17T12:08:59Z","file_size":19097730,"embargo_to":"open_access","file_id":"11908"}],"department":[{"_id":"GradSch"},{"_id":"EvBe"}],"language":[{"iso":"eng"}],"oa":1,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","citation":{"ista":"Artner C. 2022. Modulation of auxin transport via ZF proteins adjust plant response to high ambient temperature. Institute of Science and Technology Austria.","chicago":"Artner, Christina. “Modulation of Auxin Transport via ZF Proteins Adjust Plant Response to High Ambient Temperature.” Institute of Science and Technology Austria, 2022. <a href=\"https://doi.org/10.15479/at:ista:11879\">https://doi.org/10.15479/at:ista:11879</a>.","mla":"Artner, Christina. <i>Modulation of Auxin Transport via ZF Proteins Adjust Plant Response to High Ambient Temperature</i>. Institute of Science and Technology Austria, 2022, doi:<a href=\"https://doi.org/10.15479/at:ista:11879\">10.15479/at:ista:11879</a>.","apa":"Artner, C. (2022). <i>Modulation of auxin transport via ZF proteins adjust plant response to high ambient temperature</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/at:ista:11879\">https://doi.org/10.15479/at:ista:11879</a>","ama":"Artner C. Modulation of auxin transport via ZF proteins adjust plant response to high ambient temperature. 2022. doi:<a href=\"https://doi.org/10.15479/at:ista:11879\">10.15479/at:ista:11879</a>","short":"C. Artner, Modulation of Auxin Transport via ZF Proteins Adjust Plant Response to High Ambient Temperature, Institute of Science and Technology Austria, 2022.","ieee":"C. Artner, “Modulation of auxin transport via ZF proteins adjust plant response to high ambient temperature,” Institute of Science and Technology Austria, 2022."}},{"quality_controlled":"1","ddc":["510"],"date_updated":"2023-02-21T10:08:07Z","_id":"11916","type":"journal_article","doi":"10.1007/s43036-022-00199-w","article_processing_charge":"Yes (via OA deal)","publisher":"Springer Nature","acknowledgement":"The author was supported by the German Academic Scholarship Foundation (Studienstiftung des deutschen Volkes) and by the German Research Foundation (DFG) via RTG 1523/2. The author would like to thank Daniel Lenz for his support and encouragement during the author’s ongoing graduate studies and him as well as Marcel Schmidt for fruitful discussions on domination of quadratic forms. He wants to thank Batu Güneysu and Peter Stollmann for valuable comments on a preliminary version of this article. He would also like to thank the organizers of the conference Analysis and Geometry on Graphs and Manifolds in Potsdam, where the initial motivation of this article was conceived, and the organizers of the intense activity period Metric Measure Spaces and Ricci Curvature at MPIM in Bonn, where this work was finished.\r\nOpen access funding provided by Institute of Science and Technology (IST Austria).","date_published":"2022-07-01T00:00:00Z","publication":"Advances in Operator Theory","status":"public","keyword":["Algebra and Number Theory","Analysis"],"year":"2022","publication_status":"published","publication_identifier":{"eissn":["2538-225X"]},"file_date_updated":"2022-08-18T08:02:34Z","has_accepted_license":"1","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","short":"CC BY (4.0)"},"abstract":[{"lang":"eng","text":"A domain is called Kac regular for a quadratic form on L2 if every functions vanishing almost everywhere outside the domain can be approximated in form norm by functions with compact support in the domain. It is shown that this notion is stable under domination of quadratic forms. As applications measure perturbations of quasi-regular Dirichlet forms, Cheeger energies on metric measure spaces and Schrödinger operators on manifolds are studied. Along the way a characterization of the Sobolev space with Dirichlet boundary conditions on domains in infinitesimally Riemannian metric measure spaces is obtained."}],"intvolume":"         7","volume":7,"article_type":"original","date_created":"2022-08-18T07:22:24Z","author":[{"last_name":"Wirth","full_name":"Wirth, Melchior","id":"88644358-0A0E-11EA-8FA5-49A33DDC885E","orcid":"0000-0002-0519-4241","first_name":"Melchior"}],"scopus_import":"1","day":"01","oa_version":"Published Version","title":"Kac regularity and domination of quadratic forms","issue":"3","citation":{"ieee":"M. Wirth, “Kac regularity and domination of quadratic forms,” <i>Advances in Operator Theory</i>, vol. 7, no. 3. Springer Nature, 2022.","short":"M. Wirth, Advances in Operator Theory 7 (2022).","ama":"Wirth M. Kac regularity and domination of quadratic forms. <i>Advances in Operator Theory</i>. 2022;7(3). doi:<a href=\"https://doi.org/10.1007/s43036-022-00199-w\">10.1007/s43036-022-00199-w</a>","apa":"Wirth, M. (2022). Kac regularity and domination of quadratic forms. <i>Advances in Operator Theory</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s43036-022-00199-w\">https://doi.org/10.1007/s43036-022-00199-w</a>","mla":"Wirth, Melchior. “Kac Regularity and Domination of Quadratic Forms.” <i>Advances in Operator Theory</i>, vol. 7, no. 3, 38, Springer Nature, 2022, doi:<a href=\"https://doi.org/10.1007/s43036-022-00199-w\">10.1007/s43036-022-00199-w</a>.","ista":"Wirth M. 2022. Kac regularity and domination of quadratic forms. Advances in Operator Theory. 7(3), 38.","chicago":"Wirth, Melchior. “Kac Regularity and Domination of Quadratic Forms.” <i>Advances in Operator Theory</i>. Springer Nature, 2022. <a href=\"https://doi.org/10.1007/s43036-022-00199-w\">https://doi.org/10.1007/s43036-022-00199-w</a>."},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa":1,"language":[{"iso":"eng"}],"department":[{"_id":"JaMa"}],"file":[{"file_id":"11921","file_size":389060,"date_created":"2022-08-18T08:02:34Z","creator":"dernst","date_updated":"2022-08-18T08:02:34Z","relation":"main_file","checksum":"913474844a1b38264fb710746d5e2e98","file_name":"2022_AdvancesOperatorTheory_Wirth.pdf","success":1,"content_type":"application/pdf","access_level":"open_access"}],"article_number":"38","month":"07"},{"oa":1,"language":[{"iso":"eng"}],"citation":{"ieee":"S. A. E. Rademacher and R. Seiringer, “Large deviation estimates for weakly interacting bosons,” <i>Journal of Statistical Physics</i>, vol. 188. Springer Nature, 2022.","short":"S.A.E. Rademacher, R. Seiringer, Journal of Statistical Physics 188 (2022).","ama":"Rademacher SAE, Seiringer R. Large deviation estimates for weakly interacting bosons. <i>Journal of Statistical Physics</i>. 2022;188. doi:<a href=\"https://doi.org/10.1007/s10955-022-02940-4\">10.1007/s10955-022-02940-4</a>","apa":"Rademacher, S. A. E., &#38; Seiringer, R. (2022). Large deviation estimates for weakly interacting bosons. <i>Journal of Statistical Physics</i>. Springer Nature. <a href=\"https://doi.org/10.1007/s10955-022-02940-4\">https://doi.org/10.1007/s10955-022-02940-4</a>","mla":"Rademacher, Simone Anna Elvira, and Robert Seiringer. “Large Deviation Estimates for Weakly Interacting Bosons.” <i>Journal of Statistical Physics</i>, vol. 188, 9, Springer Nature, 2022, doi:<a href=\"https://doi.org/10.1007/s10955-022-02940-4\">10.1007/s10955-022-02940-4</a>.","ista":"Rademacher SAE, Seiringer R. 2022. Large deviation estimates for weakly interacting bosons. Journal of Statistical Physics. 188, 9.","chicago":"Rademacher, Simone Anna Elvira, and Robert Seiringer. “Large Deviation Estimates for Weakly Interacting Bosons.” <i>Journal of Statistical Physics</i>. Springer Nature, 2022. <a href=\"https://doi.org/10.1007/s10955-022-02940-4\">https://doi.org/10.1007/s10955-022-02940-4</a>."},"user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","month":"07","department":[{"_id":"RoSe"}],"file":[{"file_id":"11922","date_created":"2022-08-18T08:09:00Z","file_size":483481,"creator":"dernst","date_updated":"2022-08-18T08:09:00Z","relation":"main_file","checksum":"44418cb44f07fa21ed3907f85abf7f39","file_name":"2022_JournalStatisticalPhysics_Rademacher.pdf","success":1,"content_type":"application/pdf","access_level":"open_access"}],"article_number":"9","has_accepted_license":"1","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","short":"CC BY (4.0)"},"abstract":[{"lang":"eng","text":"We study the many-body dynamics of an initially factorized bosonic wave function in the mean-field regime. We prove large deviation estimates for the fluctuations around the condensate. We derive an upper bound extending a recent result to more general interactions. Furthermore, we derive a new lower bound which agrees with the upper bound in leading order."}],"intvolume":"       188","file_date_updated":"2022-08-18T08:09:00Z","publication_identifier":{"eissn":["1572-9613"],"issn":["0022-4715"]},"publication_status":"published","scopus_import":"1","day":"01","author":[{"full_name":"Rademacher, Simone Anna Elvira","id":"856966FE-A408-11E9-977E-802DE6697425","last_name":"Rademacher","orcid":"0000-0001-5059-4466","first_name":"Simone Anna Elvira"},{"orcid":"0000-0002-6781-0521","first_name":"Robert","last_name":"Seiringer","full_name":"Seiringer, Robert","id":"4AFD0470-F248-11E8-B48F-1D18A9856A87"}],"title":"Large deviation estimates for weakly interacting bosons","oa_version":"Published Version","volume":188,"date_created":"2022-08-18T07:23:26Z","article_type":"original","status":"public","publication":"Journal of Statistical Physics","project":[{"_id":"25C6DC12-B435-11E9-9278-68D0E5697425","grant_number":"694227","name":"Analysis of quantum many-body systems","call_identifier":"H2020"},{"name":"ISTplus - Postdoctoral Fellowships","grant_number":"754411","call_identifier":"H2020","_id":"260C2330-B435-11E9-9278-68D0E5697425"}],"ec_funded":1,"acknowledgement":"The authors thank Gérard Ben Arous for pointing out the question of a lower bound. Funding from the European Union’s Horizon 2020 research and innovation programme under the ERC Grant Agreement No. 694227 (R.S.) and under the Marie Skłodowska-Curie Grant Agreement No. 754411 (S.R.) is gratefully acknowledged.\r\nOpen access funding provided by IST Austria.","date_published":"2022-07-01T00:00:00Z","isi":1,"year":"2022","external_id":{"isi":["000805175000001"]},"keyword":["Mathematical Physics","Statistical and Nonlinear Physics"],"ddc":["510"],"quality_controlled":"1","article_processing_charge":"Yes (via OA deal)","doi":"10.1007/s10955-022-02940-4","publisher":"Springer Nature","_id":"11917","date_updated":"2023-08-03T12:55:58Z","type":"journal_article"},{"page":"136","ddc":["573"],"date_updated":"2023-09-05T12:02:14Z","_id":"11932","type":"dissertation","doi":"10.15479/at:ista:11932","alternative_title":["ISTA Thesis"],"article_processing_charge":"No","publisher":"Institute of Science and Technology Austria","ec_funded":1,"date_published":"2022-08-19T00:00:00Z","acknowledgement":"I acknowledge the support from the European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie Grant Agreement No. 665385.","degree_awarded":"PhD","project":[{"_id":"2564DBCA-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","grant_number":"665385","name":"International IST Doctoral Program"}],"status":"public","year":"2022","related_material":{"record":[{"status":"public","relation":"part_of_dissertation","id":"10077"},{"id":"6194","relation":"part_of_dissertation","status":"public"}]},"publication_status":"published","publication_identifier":{"issn":["2663-337X"]},"file_date_updated":"2023-06-20T22:30:04Z","has_accepted_license":"1","abstract":[{"text":"The ability to form and retrieve memories is central to survival. In mammals, the hippocampus\r\nis a brain region essential to the acquisition and consolidation of new memories. It is also\r\ninvolved in keeping track of one’s position in space and aids navigation. Although this\r\nspace-memory has been a source of contradiction, evidence supports the view that the role of\r\nthe hippocampus in navigation is memory, thanks to the formation of cognitive maps. First\r\nintroduced by Tolman in 1948, cognitive maps are generally used to organize experiences in\r\nmemory; however, the detailed mechanisms by which these maps are formed and stored are not\r\nyet agreed upon. Some influential theories describe this process as involving three fundamental\r\nsteps: initial encoding by the hippocampus, interactions between the hippocampus and other\r\ncortical areas, and long-term extra-hippocampal consolidation. In this thesis, I will show how\r\nthe investigation of cognitive maps of space helped to shed light on each of these three memory\r\nprocesses.\r\nThe first study included in this thesis deals with the initial encoding of spatial memories in\r\nthe hippocampus. Much is known about encoding at the level of single cells, but less about\r\ntheir co-activity or joint contribution to the encoding of novel spatial information. I will\r\ndescribe the structure of an interaction network that allows for efficient encoding of noisy\r\nspatial information during the first exploration of a novel environment.\r\nThe second study describes the interactions between the hippocampus and the prefrontal\r\ncortex (PFC), two areas directly and indirectly connected. It is known that the PFC, in concert\r\nwith the hippocampus, is involved in various processes, including memory storage and spatial\r\nnavigation. Nonetheless, the detailed mechanisms by which PFC receives information from the\r\nhippocampus are not clear. I will show how a transient improvement in theta phase locking of\r\nPFC cells enables interactions of cell pairs across the two regions.\r\nThe third study describes the learning of behaviorally-relevant spatial locations in the hippocampus and the medial entorhinal cortex. I will show how the accumulation of firing around\r\ngoal locations, a correlate of learning, can shed light on the transition from short- to long-term\r\nspatial memories and the speed of consolidation in different brain areas.\r\nThe studies included in this thesis represent the main scientific contributions of my Ph.D. They\r\ninvolve statistical analyses and models of neural responses of cells in different brain areas of\r\nrats executing spatial tasks. I will conclude the thesis by discussing the impact of the findings\r\non principles of memory formation and retention, including the mechanisms, the speed, and\r\nthe duration of these processes.","lang":"eng"}],"date_created":"2022-08-19T08:52:30Z","author":[{"orcid":"0000-0001-8849-6570","first_name":"Michele","last_name":"Nardin","id":"30BD0376-F248-11E8-B48F-1D18A9856A87","full_name":"Nardin, Michele"}],"day":"19","title":"On the encoding, transfer, and consolidation of spatial memories","oa_version":"Published Version","citation":{"apa":"Nardin, M. (2022). <i>On the encoding, transfer, and consolidation of spatial memories</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/at:ista:11932\">https://doi.org/10.15479/at:ista:11932</a>","mla":"Nardin, Michele. <i>On the Encoding, Transfer, and Consolidation of Spatial Memories</i>. Institute of Science and Technology Austria, 2022, doi:<a href=\"https://doi.org/10.15479/at:ista:11932\">10.15479/at:ista:11932</a>.","ista":"Nardin M. 2022. On the encoding, transfer, and consolidation of spatial memories. Institute of Science and Technology Austria.","chicago":"Nardin, Michele. “On the Encoding, Transfer, and Consolidation of Spatial Memories.” Institute of Science and Technology Austria, 2022. <a href=\"https://doi.org/10.15479/at:ista:11932\">https://doi.org/10.15479/at:ista:11932</a>.","ieee":"M. Nardin, “On the encoding, transfer, and consolidation of spatial memories,” Institute of Science and Technology Austria, 2022.","short":"M. Nardin, On the Encoding, Transfer, and Consolidation of Spatial Memories, Institute of Science and Technology Austria, 2022.","ama":"Nardin M. On the encoding, transfer, and consolidation of spatial memories. 2022. doi:<a href=\"https://doi.org/10.15479/at:ista:11932\">10.15479/at:ista:11932</a>"},"user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","oa":1,"language":[{"iso":"eng"}],"department":[{"_id":"GradSch"},{"_id":"JoCs"}],"file":[{"relation":"source_file","checksum":"2dbb70c74aaa3b64c1f463e943baf09c","file_name":"Michele Nardin, Ph.D. Thesis - ISTA (1).zip","access_level":"closed","content_type":"application/zip","file_id":"11935","embargo_to":"open_access","date_created":"2022-08-19T16:31:34Z","file_size":13515457,"creator":"mnardin","date_updated":"2023-06-20T22:30:04Z"},{"relation":"main_file","checksum":"0ec94035ea35a47a9f589ed168e60b48","file_name":"Michele_Nardin_Phd_Thesis_PDFA.pdf","access_level":"open_access","content_type":"application/pdf","file_id":"11941","file_size":9906458,"date_created":"2022-08-22T09:43:50Z","date_updated":"2023-06-20T22:30:04Z","creator":"mnardin","embargo":"2023-06-19"}],"supervisor":[{"full_name":"Csicsvari, Jozsef L","id":"3FA14672-F248-11E8-B48F-1D18A9856A87","last_name":"Csicsvari","orcid":"0000-0002-5193-4036","first_name":"Jozsef L"}],"month":"08"},{"doi":"10.1038/s41467-022-32374-1","article_processing_charge":"No","publisher":"Springer Nature","date_updated":"2023-08-03T13:00:40Z","_id":"11937","type":"journal_article","ddc":["540"],"quality_controlled":"1","isi":1,"year":"2022","external_id":{"pmid":["35948550"],"isi":["000838655300022"]},"status":"public","publication":"Nature Communications","pmid":1,"date_published":"2022-08-10T00:00:00Z","acknowledgement":"We thank Chris Pickard for providing the initial structures of high-pressure ice phases and for useful advice. A.R. and B.C. acknowledge resources provided by the Cambridge Tier-2 system operated by the University of Cambridge Research Computing Service funded by EPSRC Tier-2 capital grant EP/P020259/1. M.B. was supported by the European Union within the Marie Skłodowska-Curie actions (xICE grant 894725) and acknowledges computational resources at North-German Supercomputing Alliance (HLRN) facilities. S.H. and M.M. acknowledge support from LDRD 19-ERD-031 and computing support from the Lawrence Livermore National Laboratory (LLNL) Institutional Computing Grand Challenge programme. F.C. acknowledges support from the US DOE Office of Science, Office of Fusion Energy Sciences. Lawrence Livermore National Laboratory is operated by Lawrence Livermore National Security, LLC, for the U.S. Department of Energy, National Nuclear Security Administration under Contract DE-AC52-07NA27344.","author":[{"first_name":"Aleks","full_name":"Reinhardt, Aleks","last_name":"Reinhardt"},{"full_name":"Bethkenhagen, Mandy","last_name":"Bethkenhagen","first_name":"Mandy"},{"full_name":"Coppari, Federica","last_name":"Coppari","first_name":"Federica"},{"first_name":"Marius","full_name":"Millot, Marius","last_name":"Millot"},{"first_name":"Sebastien","full_name":"Hamel, Sebastien","last_name":"Hamel"},{"orcid":"0000-0002-3584-9632","first_name":"Bingqing","full_name":"Cheng, Bingqing","id":"cbe3cda4-d82c-11eb-8dc7-8ff94289fcc9","last_name":"Cheng"}],"day":"10","scopus_import":"1","oa_version":"Published Version","title":"Thermodynamics of high-pressure ice phases explored with atomistic simulations","volume":13,"article_type":"original","date_created":"2022-08-21T22:01:55Z","has_accepted_license":"1","tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","short":"CC BY (4.0)"},"intvolume":"        13","abstract":[{"text":"Most experimentally known high-pressure ice phases have a body-centred cubic (bcc) oxygen lattice. Our large-scale molecular-dynamics simulations with a machine-learning potential indicate that, amongst these bcc ice phases, ices VII, VII′ and X are the same thermodynamic phase under different conditions, whereas superionic ice VII″ has a first-order phase boundary with ice VII′. Moreover, at about 300 GPa, the transformation between ice X and the Pbcm phase has a sharp structural change but no apparent activation barrier, whilst at higher pressures the barrier gradually increases. Our study thus clarifies the phase behaviour of the high-pressure ices and reveals peculiar solid–solid transition mechanisms not known in other systems.","lang":"eng"}],"publication_status":"published","publication_identifier":{"eissn":["2041-1723"]},"file_date_updated":"2022-08-22T06:33:02Z","month":"08","department":[{"_id":"BiCh"}],"file":[{"relation":"main_file","checksum":"8ff9b689cde59fd3a9959a9f01929dea","file_name":"2022_NatureCommunications_Reinhardt.pdf","success":1,"content_type":"application/pdf","access_level":"open_access","file_id":"11939","date_created":"2022-08-22T06:33:02Z","file_size":1767206,"creator":"dernst","date_updated":"2022-08-22T06:33:02Z"}],"article_number":"4707","oa":1,"language":[{"iso":"eng"}],"citation":{"apa":"Reinhardt, A., Bethkenhagen, M., Coppari, F., Millot, M., Hamel, S., &#38; Cheng, B. (2022). Thermodynamics of high-pressure ice phases explored with atomistic simulations. <i>Nature Communications</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41467-022-32374-1\">https://doi.org/10.1038/s41467-022-32374-1</a>","mla":"Reinhardt, Aleks, et al. “Thermodynamics of High-Pressure Ice Phases Explored with Atomistic Simulations.” <i>Nature Communications</i>, vol. 13, 4707, Springer Nature, 2022, doi:<a href=\"https://doi.org/10.1038/s41467-022-32374-1\">10.1038/s41467-022-32374-1</a>.","chicago":"Reinhardt, Aleks, Mandy Bethkenhagen, Federica Coppari, Marius Millot, Sebastien Hamel, and Bingqing Cheng. “Thermodynamics of High-Pressure Ice Phases Explored with Atomistic Simulations.” <i>Nature Communications</i>. Springer Nature, 2022. <a href=\"https://doi.org/10.1038/s41467-022-32374-1\">https://doi.org/10.1038/s41467-022-32374-1</a>.","ista":"Reinhardt A, Bethkenhagen M, Coppari F, Millot M, Hamel S, Cheng B. 2022. Thermodynamics of high-pressure ice phases explored with atomistic simulations. Nature Communications. 13, 4707.","ieee":"A. Reinhardt, M. Bethkenhagen, F. Coppari, M. Millot, S. Hamel, and B. Cheng, “Thermodynamics of high-pressure ice phases explored with atomistic simulations,” <i>Nature Communications</i>, vol. 13. Springer Nature, 2022.","short":"A. Reinhardt, M. Bethkenhagen, F. Coppari, M. Millot, S. Hamel, B. Cheng, Nature Communications 13 (2022).","ama":"Reinhardt A, Bethkenhagen M, Coppari F, Millot M, Hamel S, Cheng B. Thermodynamics of high-pressure ice phases explored with atomistic simulations. <i>Nature Communications</i>. 2022;13. doi:<a href=\"https://doi.org/10.1038/s41467-022-32374-1\">10.1038/s41467-022-32374-1</a>"},"user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8"},{"year":"2022","related_material":{"record":[{"id":"9296","relation":"earlier_version","status":"public"}]},"external_id":{"arxiv":["2101.03928"]},"ec_funded":1,"acknowledgement":"A.A. funded by the Marie Sklodowska-Curie grant agreement No 754411. Z.M. partially funded by Wittgenstein Prize, Austrian Science Fund (FWF), grant no. Z 342-N31. I.P., D.P., and B.V. partially supported by FWF within the collaborative DACH project Arrangements and Drawings as FWF project I 3340-N35. A.P. supported by a Schrödinger fellowship of the FWF: J-3847-N35. J.T. partially supported by ERC Start grant no. (279307: Graph Games), FWF grant no. P23499-N23 and S11407-N23 (RiSE).","date_published":"2022-06-01T00:00:00Z","status":"public","publication":"Journal of Graph Algorithms and Applications","project":[{"call_identifier":"H2020","name":"ISTplus - Postdoctoral Fellowships","grant_number":"754411","_id":"260C2330-B435-11E9-9278-68D0E5697425"},{"name":"The Wittgenstein Prize","grant_number":"Z00342","call_identifier":"FWF","_id":"268116B8-B435-11E9-9278-68D0E5697425"},{"_id":"2581B60A-B435-11E9-9278-68D0E5697425","name":"Quantitative Graph Games: Theory and Applications","grant_number":"279307","call_identifier":"FP7"},{"_id":"2584A770-B435-11E9-9278-68D0E5697425","call_identifier":"FWF","name":"Modern Graph Algorithmic Techniques in Formal Verification","grant_number":"P 23499-N23"},{"call_identifier":"FWF","name":"Game Theory","grant_number":"S11407","_id":"25863FF4-B435-11E9-9278-68D0E5697425"}],"_id":"11938","date_updated":"2023-02-23T13:54:21Z","type":"journal_article","article_processing_charge":"No","doi":"10.7155/jgaa.00591","publisher":"Brown University","quality_controlled":"1","page":"225-240","ddc":["000"],"department":[{"_id":"UlWa"},{"_id":"HeEd"},{"_id":"KrCh"}],"file":[{"checksum":"dc6e255e3558faff924fd9e370886c11","relation":"main_file","content_type":"application/pdf","access_level":"open_access","file_name":"2022_JourGraphAlgorithmsApplic_Aichholzer.pdf","success":1,"file_id":"11940","creator":"dernst","date_updated":"2022-08-22T06:42:42Z","date_created":"2022-08-22T06:42:42Z","file_size":694538}],"month":"06","arxiv":1,"citation":{"ama":"Aichholzer O, Arroyo Guevara AM, Masárová Z, et al. On compatible matchings. <i>Journal of Graph Algorithms and Applications</i>. 2022;26(2):225-240. doi:<a href=\"https://doi.org/10.7155/jgaa.00591\">10.7155/jgaa.00591</a>","short":"O. Aichholzer, A.M. Arroyo Guevara, Z. Masárová, I. Parada, D. Perz, A. Pilz, J. Tkadlec, B. Vogtenhuber, Journal of Graph Algorithms and Applications 26 (2022) 225–240.","ieee":"O. Aichholzer <i>et al.</i>, “On compatible matchings,” <i>Journal of Graph Algorithms and Applications</i>, vol. 26, no. 2. Brown University, pp. 225–240, 2022.","ista":"Aichholzer O, Arroyo Guevara AM, Masárová Z, Parada I, Perz D, Pilz A, Tkadlec J, Vogtenhuber B. 2022. On compatible matchings. Journal of Graph Algorithms and Applications. 26(2), 225–240.","chicago":"Aichholzer, Oswin, Alan M Arroyo Guevara, Zuzana Masárová, Irene Parada, Daniel Perz, Alexander Pilz, Josef Tkadlec, and Birgit Vogtenhuber. “On Compatible Matchings.” <i>Journal of Graph Algorithms and Applications</i>. Brown University, 2022. <a href=\"https://doi.org/10.7155/jgaa.00591\">https://doi.org/10.7155/jgaa.00591</a>.","mla":"Aichholzer, Oswin, et al. “On Compatible Matchings.” <i>Journal of Graph Algorithms and Applications</i>, vol. 26, no. 2, Brown University, 2022, pp. 225–40, doi:<a href=\"https://doi.org/10.7155/jgaa.00591\">10.7155/jgaa.00591</a>.","apa":"Aichholzer, O., Arroyo Guevara, A. M., Masárová, Z., Parada, I., Perz, D., Pilz, A., … Vogtenhuber, B. (2022). On compatible matchings. <i>Journal of Graph Algorithms and Applications</i>. Brown University. <a href=\"https://doi.org/10.7155/jgaa.00591\">https://doi.org/10.7155/jgaa.00591</a>"},"issue":"2","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa":1,"language":[{"iso":"eng"}],"volume":26,"date_created":"2022-08-21T22:01:56Z","article_type":"original","scopus_import":"1","day":"01","author":[{"last_name":"Aichholzer","full_name":"Aichholzer, Oswin","first_name":"Oswin"},{"last_name":"Arroyo Guevara","id":"3207FDC6-F248-11E8-B48F-1D18A9856A87","full_name":"Arroyo Guevara, Alan M","orcid":"0000-0003-2401-8670","first_name":"Alan M"},{"first_name":"Zuzana","orcid":"0000-0002-6660-1322","full_name":"Masárová, Zuzana","id":"45CFE238-F248-11E8-B48F-1D18A9856A87","last_name":"Masárová"},{"first_name":"Irene","full_name":"Parada, Irene","last_name":"Parada"},{"last_name":"Perz","full_name":"Perz, Daniel","first_name":"Daniel"},{"full_name":"Pilz, Alexander","last_name":"Pilz","first_name":"Alexander"},{"last_name":"Tkadlec","full_name":"Tkadlec, Josef","id":"3F24CCC8-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-1097-9684","first_name":"Josef"},{"last_name":"Vogtenhuber","full_name":"Vogtenhuber, Birgit","first_name":"Birgit"}],"oa_version":"Published Version","title":"On compatible matchings","file_date_updated":"2022-08-22T06:42:42Z","publication_status":"published","publication_identifier":{"issn":["1526-1719"]},"has_accepted_license":"1","abstract":[{"lang":"eng","text":"A matching is compatible to two or more labeled point sets of size n with labels {1, . . . , n} if its straight-line drawing on each of these point sets is crossing-free. We study the maximum number of edges in a matching compatible to two or more labeled point sets in general position in the plane. We show that for any two labeled sets of n points in convex position there exists a compatible matching with ⌊√2n + 1 − 1⌋ edges. More generally, for any ℓ labeled point sets we construct compatible matchings of size Ω(n1/ℓ). As a corresponding upper bound, we use probabilistic arguments to show that for any ℓ given sets of n points there exists a labeling of each set such that the largest compatible matching has O(n2/(ℓ+1)) edges. Finally, we show that Θ(log n) copies of any set of n points are necessary and sufficient for the existence of labelings of these point sets such that any compatible matching consists only of a single edge."}],"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","short":"CC BY (4.0)"},"intvolume":"        26"},{"author":[{"full_name":"Velicky, Philipp","id":"39BDC62C-F248-11E8-B48F-1D18A9856A87","last_name":"Velicky","orcid":"0000-0002-2340-7431","first_name":"Philipp"},{"last_name":"Miguel Villalba","id":"3FB91342-F248-11E8-B48F-1D18A9856A87","full_name":"Miguel Villalba, Eder","orcid":"0000-0001-5665-0430","first_name":"Eder"},{"first_name":"Julia M","orcid":"0000-0003-3862-1235","id":"443DB6DE-F248-11E8-B48F-1D18A9856A87","full_name":"Michalska, Julia M","last_name":"Michalska"},{"first_name":"Donglai","last_name":"Wei","full_name":"Wei, Donglai"},{"first_name":"Zudi","last_name":"Lin","full_name":"Lin, Zudi"},{"last_name":"Watson","id":"63836096-4690-11EA-BD4E-32803DDC885E","full_name":"Watson, Jake","orcid":"0000-0002-8698-3823","first_name":"Jake"},{"first_name":"Jakob","full_name":"Troidl, Jakob","last_name":"Troidl"},{"first_name":"Johanna","last_name":"Beyer","full_name":"Beyer, Johanna"},{"first_name":"Yoav","full_name":"Ben Simon, Yoav","id":"43DF3136-F248-11E8-B48F-1D18A9856A87","last_name":"Ben Simon"},{"first_name":"Christoph M","orcid":"0000-0003-1216-9105","last_name":"Sommer","full_name":"Sommer, Christoph M","id":"4DF26D8C-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Jahr","full_name":"Jahr, Wiebke","id":"425C1CE8-F248-11E8-B48F-1D18A9856A87","first_name":"Wiebke"},{"last_name":"Cenameri","full_name":"Cenameri, Alban","id":"9ac8f577-2357-11eb-997a-e566c5550886","first_name":"Alban"},{"first_name":"Johannes","last_name":"Broichhagen","full_name":"Broichhagen, Johannes"},{"last_name":"Grant","full_name":"Grant, Seth G. N.","first_name":"Seth G. N."},{"orcid":"0000-0001-5001-4804","first_name":"Peter M","full_name":"Jonas, Peter M","id":"353C1B58-F248-11E8-B48F-1D18A9856A87","last_name":"Jonas"},{"orcid":"0000-0002-7673-7178","first_name":"Gaia","last_name":"Novarino","id":"3E57A680-F248-11E8-B48F-1D18A9856A87","full_name":"Novarino, Gaia"},{"last_name":"Pfister","full_name":"Pfister, Hanspeter","first_name":"Hanspeter"},{"orcid":"0000-0001-6511-9385","first_name":"Bernd","last_name":"Bickel","full_name":"Bickel, Bernd","id":"49876194-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Danzl","full_name":"Danzl, Johann G","id":"42EFD3B6-F248-11E8-B48F-1D18A9856A87","first_name":"Johann G","orcid":"0000-0001-8559-3973"}],"doi":"10.1101/2022.03.16.484431","day":"09","article_processing_charge":"No","oa_version":"Preprint","title":"Saturated reconstruction of living brain tissue","publisher":"Cold Spring Harbor Laboratory","date_updated":"2024-03-25T23:30:11Z","_id":"11943","type":"preprint","date_created":"2022-08-23T11:07:59Z","abstract":[{"lang":"eng","text":"Complex wiring between neurons underlies the information-processing network enabling all brain functions, including cognition and memory. For understanding how the network is structured, processes information, and changes over time, comprehensive visualization of the architecture of living brain tissue with its cellular and molecular components would open up major opportunities. However, electron microscopy (EM) provides nanometre-scale resolution required for full <jats:italic>in-silico</jats:italic> reconstruction<jats:sup>1–5</jats:sup>, yet is limited to fixed specimens and static representations. Light microscopy allows live observation, with super-resolution approaches<jats:sup>6–12</jats:sup> facilitating nanoscale visualization, but comprehensive 3D-reconstruction of living brain tissue has been hindered by tissue photo-burden, photobleaching, insufficient 3D-resolution, and inadequate signal-to-noise ratio (SNR). Here we demonstrate saturated reconstruction of living brain tissue. We developed an integrated imaging and analysis technology, adapting stimulated emission depletion (STED) microscopy<jats:sup>6,13</jats:sup> in extracellularly labelled tissue<jats:sup>14</jats:sup> for high SNR and near-isotropic resolution. Centrally, a two-stage deep-learning approach leveraged previously obtained information on sample structure to drastically reduce photo-burden and enable automated volumetric reconstruction down to single synapse level. Live reconstruction provides unbiased analysis of tissue architecture across time in relation to functional activity and targeted activation, and contextual understanding of molecular labelling. This adoptable technology will facilitate novel insights into the dynamic functional architecture of living brain tissue."}],"main_file_link":[{"open_access":"1","url":"https://doi.org/10.1101/2022.03.16.484431"}],"publication_status":"submitted","year":"2022","related_material":{"record":[{"id":"12470","relation":"dissertation_contains","status":"public"}]},"month":"05","department":[{"_id":"PeJo"},{"_id":"GaNo"},{"_id":"BeBi"},{"_id":"JoDa"}],"oa":1,"publication":"bioRxiv","status":"public","language":[{"iso":"eng"}],"citation":{"ieee":"P. Velicky <i>et al.</i>, “Saturated reconstruction of living brain tissue,” <i>bioRxiv</i>. Cold Spring Harbor Laboratory.","short":"P. Velicky, E. Miguel Villalba, J.M. Michalska, D. Wei, Z. Lin, J. Watson, J. Troidl, J. Beyer, Y. Ben Simon, C.M. Sommer, W. Jahr, A. Cenameri, J. Broichhagen, S.G.N. Grant, P.M. Jonas, G. Novarino, H. Pfister, B. Bickel, J.G. Danzl, BioRxiv (n.d.).","ama":"Velicky P, Miguel Villalba E, Michalska JM, et al. Saturated reconstruction of living brain tissue. <i>bioRxiv</i>. doi:<a href=\"https://doi.org/10.1101/2022.03.16.484431\">10.1101/2022.03.16.484431</a>","apa":"Velicky, P., Miguel Villalba, E., Michalska, J. M., Wei, D., Lin, Z., Watson, J., … Danzl, J. G. (n.d.). Saturated reconstruction of living brain tissue. <i>bioRxiv</i>. Cold Spring Harbor Laboratory. <a href=\"https://doi.org/10.1101/2022.03.16.484431\">https://doi.org/10.1101/2022.03.16.484431</a>","mla":"Velicky, Philipp, et al. “Saturated Reconstruction of Living Brain Tissue.” <i>BioRxiv</i>, Cold Spring Harbor Laboratory, doi:<a href=\"https://doi.org/10.1101/2022.03.16.484431\">10.1101/2022.03.16.484431</a>.","chicago":"Velicky, Philipp, Eder Miguel Villalba, Julia M Michalska, Donglai Wei, Zudi Lin, Jake Watson, Jakob Troidl, et al. “Saturated Reconstruction of Living Brain Tissue.” <i>BioRxiv</i>. Cold Spring Harbor Laboratory, n.d. <a href=\"https://doi.org/10.1101/2022.03.16.484431\">https://doi.org/10.1101/2022.03.16.484431</a>.","ista":"Velicky P, Miguel Villalba E, Michalska JM, Wei D, Lin Z, Watson J, Troidl J, Beyer J, Ben Simon Y, Sommer CM, Jahr W, Cenameri A, Broichhagen J, Grant SGN, Jonas PM, Novarino G, Pfister H, Bickel B, Danzl JG. Saturated reconstruction of living brain tissue. bioRxiv, <a href=\"https://doi.org/10.1101/2022.03.16.484431\">10.1101/2022.03.16.484431</a>."},"date_published":"2022-05-09T00:00:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87"},{"user_id":"8b945eb4-e2f2-11eb-945a-df72226e66a9","citation":{"mla":"Schulz, Rouven. <i>Chimeric G Protein-Coupled Receptors Mimic Distinct Signaling Pathways and Modulate Microglia Function</i>. Institute of Science and Technology Austria, 2022, doi:<a href=\"https://doi.org/10.15479/at:ista:11945\">10.15479/at:ista:11945</a>.","apa":"Schulz, R. (2022). <i>Chimeric G protein-coupled receptors mimic distinct signaling pathways and modulate microglia function</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/at:ista:11945\">https://doi.org/10.15479/at:ista:11945</a>","ista":"Schulz R. 2022. Chimeric G protein-coupled receptors mimic distinct signaling pathways and modulate microglia function. Institute of Science and Technology Austria.","chicago":"Schulz, Rouven. “Chimeric G Protein-Coupled Receptors Mimic Distinct Signaling Pathways and Modulate Microglia Function.” Institute of Science and Technology Austria, 2022. <a href=\"https://doi.org/10.15479/at:ista:11945\">https://doi.org/10.15479/at:ista:11945</a>.","short":"R. Schulz, Chimeric G Protein-Coupled Receptors Mimic Distinct Signaling Pathways and Modulate Microglia Function, Institute of Science and Technology Austria, 2022.","ieee":"R. Schulz, “Chimeric G protein-coupled receptors mimic distinct signaling pathways and modulate microglia function,” Institute of Science and Technology Austria, 2022.","ama":"Schulz R. Chimeric G protein-coupled receptors mimic distinct signaling pathways and modulate microglia function. 2022. doi:<a href=\"https://doi.org/10.15479/at:ista:11945\">10.15479/at:ista:11945</a>"},"language":[{"iso":"eng"}],"oa":1,"file":[{"success":1,"file_name":"Thesis_Rouven_Schulz_2022_final.pdf","access_level":"open_access","content_type":"application/pdf","relation":"main_file","checksum":"61b1b666a210ff7cdd0e95ea75207a13","file_size":28079331,"date_created":"2022-08-25T08:59:57Z","date_updated":"2022-08-25T08:59:57Z","creator":"rschulz","file_id":"11970"},{"creator":"rschulz","date_updated":"2022-08-25T09:33:31Z","date_created":"2022-08-25T09:00:11Z","file_size":27226963,"file_id":"11971","access_level":"closed","content_type":"application/vnd.openxmlformats-officedocument.wordprocessingml.document","file_name":"Thesis_Rouven_Schulz_2022_final.docx","checksum":"2b8f95ea1c134dbdb927b41b1dbeeeb5","relation":"source_file"}],"department":[{"_id":"GradSch"},{"_id":"SaSi"}],"month":"08","supervisor":[{"id":"36ACD32E-F248-11E8-B48F-1D18A9856A87","full_name":"Siegert, Sandra","last_name":"Siegert","orcid":"0000-0001-8635-0877","first_name":"Sandra"}],"file_date_updated":"2022-08-25T09:33:31Z","publication_identifier":{"issn":["2663-337X"]},"publication_status":"published","acknowledged_ssus":[{"_id":"Bio"},{"_id":"PreCl"},{"_id":"LifeSc"}],"tmp":{"name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","short":"CC BY (4.0)"},"abstract":[{"text":"G protein-coupled receptors (GPCRs) respond to specific ligands and regulate multiple processes ranging from cell growth and immune responses to neuronal signal transmission. However, ligands for many GPCRs remain unknown, suffer from off-target effects or have poor bioavailability. Additional challenges exist to dissect cell-type specific responses when the same GPCR is expressed on several cell types within the body. Here, we overcome these limitations by engineering DREADD-based GPCR chimeras that selectively bind their agonist clozapine-N-oxide (CNO) and mimic a GPCR-of-interest in a desired cell type.\r\nWe validated our approach with β2-adrenergic receptor (β2AR/ADRB2) and show that our chimeric DREADD-β2AR triggers comparable responses on second messenger and kinase activity, post-translational modifications, and protein-protein interactions. Since β2AR is also enriched in microglia, which can drive inflammation in the central nervous system, we expressed chimeric DREADD-β2AR in primary microglia and successfully recapitulate β2AR-mediated filopodia formation through CNO stimulation. To dissect the role of selected GPCRs during microglial inflammation, we additionally generated DREADD-based chimeras for microglia-enriched GPR65 and GPR109A/HCAR2. In a microglia cell line, DREADD-β2AR and DREADD-GPR65 both modulated the inflammatory response with a similar profile as endogenously expressed β2AR, while DREADD-GPR109A showed no impact.\r\nOur DREADD-based approach provides the means to obtain mechanistic and functional insights into GPCR signaling on a cell-type specific level.","lang":"eng"}],"has_accepted_license":"1","date_created":"2022-08-23T11:33:11Z","oa_version":"Published Version","title":"Chimeric G protein-coupled receptors mimic distinct signaling pathways and modulate microglia function","day":"23","author":[{"id":"4C5E7B96-F248-11E8-B48F-1D18A9856A87","full_name":"Schulz, Rouven","last_name":"Schulz","orcid":"0000-0001-5297-733X","first_name":"Rouven"}],"date_published":"2022-08-23T00:00:00Z","status":"public","project":[{"_id":"267F75D8-B435-11E9-9278-68D0E5697425","name":"Modulating microglia through G protein-coupled receptor (GPCR) signaling"}],"degree_awarded":"PhD","related_material":{"record":[{"id":"11995","status":"public","relation":"dissertation_contains"}]},"year":"2022","ddc":["570"],"page":"133","type":"dissertation","_id":"11945","date_updated":"2023-08-03T13:02:26Z","publisher":"Institute of Science and Technology Austria","article_processing_charge":"No","alternative_title":["ISTA Thesis"],"doi":"10.15479/at:ista:11945"},{"abstract":[{"lang":"eng","text":"Mapping the complex and dense arrangement of cells and their connectivity in brain tissue demands nanoscale spatial resolution imaging. Super-resolution optical microscopy excels at visualizing specific molecules and individual cells but fails to provide tissue context. Here we developed Comprehensive Analysis of Tissues across Scales (CATS), a technology to densely map brain tissue architecture from millimeter regional to nanoscopic synaptic scales in diverse chemically fixed brain preparations, including rodent and human. CATS leverages fixation-compatible extracellular labeling and advanced optical readout, in particular stimulated-emission depletion and expansion microscopy, to comprehensively delineate cellular structures. It enables 3D-reconstructing single synapses and mapping synaptic connectivity by identification and tailored analysis of putative synaptic cleft regions. Applying CATS to the hippocampal mossy fiber circuitry, we demonstrate its power to reveal the system’s molecularly informed ultrastructure across spatial scales and assess local connectivity by reconstructing and quantifying the synaptic input and output structure of identified neurons."}],"main_file_link":[{"url":"https://doi.org/10.1101/2022.08.17.504272","open_access":"1"}],"publication_status":"submitted","article_processing_charge":"No","day":"18","author":[{"first_name":"Julia M","orcid":"0000-0003-3862-1235","last_name":"Michalska","full_name":"Michalska, Julia M","id":"443DB6DE-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Lyudchik","id":"46E28B80-F248-11E8-B48F-1D18A9856A87","full_name":"Lyudchik, Julia","first_name":"Julia"},{"first_name":"Philipp","orcid":"0000-0002-2340-7431","last_name":"Velicky","id":"39BDC62C-F248-11E8-B48F-1D18A9856A87","full_name":"Velicky, Philipp"},{"last_name":"Korinkova","id":"ee3cb6ca-ec98-11ea-ae11-ff703e2254ed","full_name":"Korinkova, Hana","first_name":"Hana"},{"id":"63836096-4690-11EA-BD4E-32803DDC885E","full_name":"Watson, Jake","last_name":"Watson","orcid":"0000-0002-8698-3823","first_name":"Jake"},{"first_name":"Alban","last_name":"Cenameri","id":"9ac8f577-2357-11eb-997a-e566c5550886","full_name":"Cenameri, Alban"},{"id":"4DF26D8C-F248-11E8-B48F-1D18A9856A87","full_name":"Sommer, Christoph M","last_name":"Sommer","orcid":"0000-0003-1216-9105","first_name":"Christoph M"},{"id":"41CB84B2-F248-11E8-B48F-1D18A9856A87","full_name":"Venturino, Alessandro","last_name":"Venturino","orcid":"0000-0003-2356-9403","first_name":"Alessandro"},{"last_name":"Roessler","full_name":"Roessler, Karl","first_name":"Karl"},{"first_name":"Thomas","last_name":"Czech","full_name":"Czech, Thomas"},{"orcid":"0000-0001-8635-0877","first_name":"Sandra","last_name":"Siegert","id":"36ACD32E-F248-11E8-B48F-1D18A9856A87","full_name":"Siegert, Sandra"},{"last_name":"Novarino","full_name":"Novarino, Gaia","id":"3E57A680-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-7673-7178","first_name":"Gaia"},{"last_name":"Jonas","full_name":"Jonas, Peter M","id":"353C1B58-F248-11E8-B48F-1D18A9856A87","first_name":"Peter M","orcid":"0000-0001-5001-4804"},{"last_name":"Danzl","id":"42EFD3B6-F248-11E8-B48F-1D18A9856A87","full_name":"Danzl, Johann G","orcid":"0000-0001-8559-3973","first_name":"Johann G"}],"doi":"10.1101/2022.08.17.504272","oa_version":"Preprint","title":"Uncovering brain tissue architecture across scales with super-resolution light microscopy","publisher":"Cold Spring Harbor Laboratory","_id":"11950","date_updated":"2024-03-25T23:30:11Z","date_created":"2022-08-24T08:24:52Z","type":"preprint","oa":1,"language":[{"iso":"eng"}],"publication":"bioRxiv","status":"public","citation":{"ista":"Michalska JM, Lyudchik J, Velicky P, Korinkova H, Watson J, Cenameri A, Sommer CM, Venturino A, Roessler K, Czech T, Siegert S, Novarino G, Jonas PM, Danzl JG. Uncovering brain tissue architecture across scales with super-resolution light microscopy. bioRxiv, <a href=\"https://doi.org/10.1101/2022.08.17.504272\">10.1101/2022.08.17.504272</a>.","chicago":"Michalska, Julia M, Julia Lyudchik, Philipp Velicky, Hana Korinkova, Jake Watson, Alban Cenameri, Christoph M Sommer, et al. “Uncovering Brain Tissue Architecture across Scales with Super-Resolution Light Microscopy.” <i>BioRxiv</i>. Cold Spring Harbor Laboratory, n.d. <a href=\"https://doi.org/10.1101/2022.08.17.504272\">https://doi.org/10.1101/2022.08.17.504272</a>.","mla":"Michalska, Julia M., et al. “Uncovering Brain Tissue Architecture across Scales with Super-Resolution Light Microscopy.” <i>BioRxiv</i>, Cold Spring Harbor Laboratory, doi:<a href=\"https://doi.org/10.1101/2022.08.17.504272\">10.1101/2022.08.17.504272</a>.","apa":"Michalska, J. M., Lyudchik, J., Velicky, P., Korinkova, H., Watson, J., Cenameri, A., … Danzl, J. G. (n.d.). Uncovering brain tissue architecture across scales with super-resolution light microscopy. <i>bioRxiv</i>. Cold Spring Harbor Laboratory. <a href=\"https://doi.org/10.1101/2022.08.17.504272\">https://doi.org/10.1101/2022.08.17.504272</a>","ama":"Michalska JM, Lyudchik J, Velicky P, et al. Uncovering brain tissue architecture across scales with super-resolution light microscopy. <i>bioRxiv</i>. doi:<a href=\"https://doi.org/10.1101/2022.08.17.504272\">10.1101/2022.08.17.504272</a>","short":"J.M. Michalska, J. Lyudchik, P. Velicky, H. Korinkova, J. Watson, A. Cenameri, C.M. Sommer, A. Venturino, K. Roessler, T. Czech, S. Siegert, G. Novarino, P.M. Jonas, J.G. Danzl, BioRxiv (n.d.).","ieee":"J. M. Michalska <i>et al.</i>, “Uncovering brain tissue architecture across scales with super-resolution light microscopy,” <i>bioRxiv</i>. Cold Spring Harbor Laboratory."},"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_published":"2022-08-18T00:00:00Z","year":"2022","related_material":{"record":[{"id":"12470","relation":"dissertation_contains","status":"public"}]},"month":"08","department":[{"_id":"SaSi"},{"_id":"GaNo"},{"_id":"PeJo"},{"_id":"JoDa"}]}]