[{"type":"conference","ddc":["000"],"intvolume":"      2017","month":"07","isi":1,"ec_funded":1,"page":"4990-4999","citation":{"apa":"Swoboda, P., &#38; Andres, B. (2017). A message passing algorithm for the minimum cost multicut problem (Vol. 2017, pp. 4990–4999). Presented at the CVPR: Computer Vision and Pattern Recognition, Honolulu, HA, United States: IEEE. <a href=\"https://doi.org/10.1109/CVPR.2017.530\">https://doi.org/10.1109/CVPR.2017.530</a>","chicago":"Swoboda, Paul, and Bjoern Andres. “A Message Passing Algorithm for the Minimum Cost Multicut Problem,” 2017:4990–99. IEEE, 2017. <a href=\"https://doi.org/10.1109/CVPR.2017.530\">https://doi.org/10.1109/CVPR.2017.530</a>.","ama":"Swoboda P, Andres B. A message passing algorithm for the minimum cost multicut problem. In: Vol 2017. IEEE; 2017:4990-4999. doi:<a href=\"https://doi.org/10.1109/CVPR.2017.530\">10.1109/CVPR.2017.530</a>","mla":"Swoboda, Paul, and Bjoern Andres. <i>A Message Passing Algorithm for the Minimum Cost Multicut Problem</i>. Vol. 2017, IEEE, 2017, pp. 4990–99, doi:<a href=\"https://doi.org/10.1109/CVPR.2017.530\">10.1109/CVPR.2017.530</a>.","short":"P. Swoboda, B. Andres, in:, IEEE, 2017, pp. 4990–4999.","ista":"Swoboda P, Andres B. 2017. A message passing algorithm for the minimum cost multicut problem. CVPR: Computer Vision and Pattern Recognition vol. 2017, 4990–4999.","ieee":"P. Swoboda and B. Andres, “A message passing algorithm for the minimum cost multicut problem,” presented at the CVPR: Computer Vision and Pattern Recognition, Honolulu, HA, United States, 2017, vol. 2017, pp. 4990–4999."},"quality_controlled":"1","publication_status":"published","abstract":[{"lang":"eng","text":"We propose a dual decomposition and linear program relaxation of the NP-hard minimum cost multicut problem. Unlike other polyhedral relaxations of the multicut polytope, it is amenable to efficient optimization by message passing. Like other polyhedral relaxations, it can be tightened efficiently by cutting planes.  We define an algorithm that alternates between message passing and efficient separation of cycle- and odd-wheel inequalities. This algorithm is more efficient than state-of-the-art algorithms based on linear programming, including algorithms written in the framework of leading commercial software, as we show in experiments with large instances of the problem from applications in computer vision, biomedical image analysis and data mining."}],"language":[{"iso":"eng"}],"publist_id":"6526","department":[{"_id":"VlKo"}],"publisher":"IEEE","file_date_updated":"2020-07-14T12:48:15Z","file":[{"file_id":"5849","checksum":"7e51dacefa693574581a32da3eff63dc","content_type":"application/pdf","creator":"dernst","access_level":"open_access","file_size":883264,"date_created":"2019-01-18T12:52:46Z","file_name":"Swoboda_A_Message_Passing_CVPR_2017_paper.pdf","date_updated":"2020-07-14T12:48:15Z","relation":"main_file"}],"scopus_import":"1","article_processing_charge":"No","title":"A message passing algorithm for the minimum cost multicut problem","_id":"915","date_updated":"2023-09-26T15:43:27Z","conference":{"name":"CVPR: Computer Vision and Pattern Recognition","location":"Honolulu, HA, United States","start_date":"2017-07-21","end_date":"2017-07-26"},"year":"2017","project":[{"name":"Discrete Optimization in Computer Vision: Theory and Practice","_id":"25FBA906-B435-11E9-9278-68D0E5697425","grant_number":"616160","call_identifier":"FP7"}],"has_accepted_license":"1","oa":1,"publication_identifier":{"isbn":["978-153860457-1"]},"oa_version":"Submitted Version","status":"public","author":[{"first_name":"Paul","full_name":"Swoboda, Paul","last_name":"Swoboda","id":"446560C6-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Bjoern","full_name":"Andres, Bjoern","last_name":"Andres"}],"doi":"10.1109/CVPR.2017.530","volume":2017,"date_created":"2018-12-11T11:49:11Z","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","external_id":{"isi":["000418371405009"]},"day":"01","date_published":"2017-07-01T00:00:00Z"},{"conference":{"start_date":"2017-07-21","end_date":"2017-07-26","name":"CVPR: Computer Vision and Pattern Recognition","location":"Honolulu, HA, United States"},"date_updated":"2023-09-26T15:41:40Z","_id":"916","article_processing_charge":"No","title":"A study of lagrangean decompositions and dual ascent solvers for graph matching","publication_identifier":{"isbn":["978-153860457-1"]},"oa":1,"has_accepted_license":"1","year":"2017","project":[{"_id":"25FBA906-B435-11E9-9278-68D0E5697425","name":"Discrete Optimization in Computer Vision: Theory and Practice","call_identifier":"FP7","grant_number":"616160"}],"user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","date_created":"2018-12-11T11:49:11Z","volume":2017,"doi":"10.1109/CVPR.2017.747","author":[{"id":"446560C6-F248-11E8-B48F-1D18A9856A87","last_name":"Swoboda","full_name":"Swoboda, Paul","first_name":"Paul"},{"first_name":"Carsten","full_name":"Rother, Carsten","last_name":"Rother"},{"first_name":"Carsten","full_name":"Abu Alhaija, Carsten","last_name":"Abu Alhaija"},{"last_name":"Kainmueller","first_name":"Dagmar","full_name":"Kainmueller, Dagmar"},{"full_name":"Savchynskyy, Bogdan","first_name":"Bogdan","last_name":"Savchynskyy"}],"status":"public","oa_version":"Submitted Version","date_published":"2017-01-01T00:00:00Z","day":"01","external_id":{"isi":["000418371407018"]},"ddc":["000"],"type":"conference","page":"7062-7071","ec_funded":1,"month":"01","isi":1,"intvolume":"      2017","publication_status":"published","quality_controlled":"1","citation":{"ista":"Swoboda P, Rother C, Abu Alhaija C, Kainmueller D, Savchynskyy B. 2017. A study of lagrangean decompositions and dual ascent solvers for graph matching. CVPR: Computer Vision and Pattern Recognition vol. 2017, 7062–7071.","ieee":"P. Swoboda, C. Rother, C. Abu Alhaija, D. Kainmueller, and B. Savchynskyy, “A study of lagrangean decompositions and dual ascent solvers for graph matching,” presented at the CVPR: Computer Vision and Pattern Recognition, Honolulu, HA, United States, 2017, vol. 2017, pp. 7062–7071.","mla":"Swoboda, Paul, et al. <i>A Study of Lagrangean Decompositions and Dual Ascent Solvers for Graph Matching</i>. Vol. 2017, IEEE, 2017, pp. 7062–71, doi:<a href=\"https://doi.org/10.1109/CVPR.2017.747\">10.1109/CVPR.2017.747</a>.","short":"P. Swoboda, C. Rother, C. Abu Alhaija, D. Kainmueller, B. Savchynskyy, in:, IEEE, 2017, pp. 7062–7071.","ama":"Swoboda P, Rother C, Abu Alhaija C, Kainmueller D, Savchynskyy B. A study of lagrangean decompositions and dual ascent solvers for graph matching. In: Vol 2017. IEEE; 2017:7062-7071. doi:<a href=\"https://doi.org/10.1109/CVPR.2017.747\">10.1109/CVPR.2017.747</a>","chicago":"Swoboda, Paul, Carsten Rother, Carsten Abu Alhaija, Dagmar Kainmueller, and Bogdan Savchynskyy. “A Study of Lagrangean Decompositions and Dual Ascent Solvers for Graph Matching,” 2017:7062–71. IEEE, 2017. <a href=\"https://doi.org/10.1109/CVPR.2017.747\">https://doi.org/10.1109/CVPR.2017.747</a>.","apa":"Swoboda, P., Rother, C., Abu Alhaija, C., Kainmueller, D., &#38; Savchynskyy, B. (2017). A study of lagrangean decompositions and dual ascent solvers for graph matching (Vol. 2017, pp. 7062–7071). Presented at the CVPR: Computer Vision and Pattern Recognition, Honolulu, HA, United States: IEEE. <a href=\"https://doi.org/10.1109/CVPR.2017.747\">https://doi.org/10.1109/CVPR.2017.747</a>"},"file_date_updated":"2020-07-14T12:48:15Z","file":[{"file_id":"5848","checksum":"e38a2740daad1ea178465843b5072906","content_type":"application/pdf","creator":"dernst","access_level":"open_access","file_size":944332,"date_created":"2019-01-18T12:49:38Z","file_name":"2017_CVPR_Swoboda2.pdf","date_updated":"2020-07-14T12:48:15Z","relation":"main_file"}],"scopus_import":"1","publisher":"IEEE","department":[{"_id":"VlKo"}],"language":[{"iso":"eng"}],"publist_id":"6525","abstract":[{"lang":"eng","text":"We study the quadratic assignment problem, in computer vision also known as graph matching. Two leading solvers for this problem optimize the Lagrange decomposition duals with sub-gradient and dual ascent (also known as message passing) updates. We explore this direction further and propose several additional Lagrangean relaxations of the graph matching problem along with corresponding algorithms, which are all based on a common dual ascent framework. Our extensive empirical evaluation gives several theoretical insights and suggests a new state-of-the-art anytime solver for the considered problem. Our improvement over state-of-the-art is particularly visible on a new dataset with large-scale sparse problem instances containing more than 500 graph nodes each."}]},{"external_id":{"isi":["000418371405005"]},"day":"01","date_published":"2017-07-01T00:00:00Z","oa_version":"Submitted Version","author":[{"first_name":"Paul","full_name":"Swoboda, Paul","id":"446560C6-F248-11E8-B48F-1D18A9856A87","last_name":"Swoboda"},{"full_name":"Kuske, Jan","first_name":"Jan","last_name":"Kuske"},{"last_name":"Savchynskyy","first_name":"Bogdan","full_name":"Savchynskyy, Bogdan"}],"status":"public","doi":"10.1109/CVPR.2017.526","date_created":"2018-12-11T11:49:11Z","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","volume":2017,"year":"2017","project":[{"name":"Discrete Optimization in Computer Vision: Theory and Practice","_id":"25FBA906-B435-11E9-9278-68D0E5697425","grant_number":"616160","call_identifier":"FP7"}],"has_accepted_license":"1","oa":1,"publication_identifier":{"isbn":["978-153860457-1"]},"title":"A dual ascent framework for Lagrangean decomposition of combinatorial problems","article_processing_charge":"No","date_updated":"2023-09-26T15:41:11Z","_id":"917","conference":{"start_date":"2017-07-21","end_date":"2017-07-26","name":"CVPR: Computer Vision and Pattern Recognition","location":"Honolulu, HA, United States"},"abstract":[{"text":"We  propose  a  general  dual  ascent  framework  for  Lagrangean decomposition of combinatorial problems.  Although methods of this type have shown their efficiency for a number of problems, so far there was no general algorithm applicable to multiple problem types. In this work, we propose such a general algorithm. It depends on several parameters, which can be used to optimize its performance in each particular setting. We demonstrate efficacy of our method on graph matching and multicut problems, where it outperforms state-of-the-art solvers including those based on subgradient optimization and off-the-shelf linear programming solvers.","lang":"eng"}],"publist_id":"6524","department":[{"_id":"VlKo"}],"language":[{"iso":"eng"}],"publisher":"IEEE","scopus_import":"1","file_date_updated":"2020-07-14T12:48:15Z","file":[{"date_created":"2019-01-18T12:45:55Z","file_size":898652,"date_updated":"2020-07-14T12:48:15Z","file_name":"2017_CVPR_Swoboda.pdf","relation":"main_file","file_id":"5847","content_type":"application/pdf","checksum":"72fd291046bd8e5717961bd68f6b6f03","access_level":"open_access","creator":"dernst"}],"quality_controlled":"1","citation":{"ama":"Swoboda P, Kuske J, Savchynskyy B. A dual ascent framework for Lagrangean decomposition of combinatorial problems. In: Vol 2017. IEEE; 2017:4950-4960. doi:<a href=\"https://doi.org/10.1109/CVPR.2017.526\">10.1109/CVPR.2017.526</a>","apa":"Swoboda, P., Kuske, J., &#38; Savchynskyy, B. (2017). A dual ascent framework for Lagrangean decomposition of combinatorial problems (Vol. 2017, pp. 4950–4960). Presented at the CVPR: Computer Vision and Pattern Recognition, Honolulu, HA, United States: IEEE. <a href=\"https://doi.org/10.1109/CVPR.2017.526\">https://doi.org/10.1109/CVPR.2017.526</a>","chicago":"Swoboda, Paul, Jan Kuske, and Bogdan Savchynskyy. “A Dual Ascent Framework for Lagrangean Decomposition of Combinatorial Problems,” 2017:4950–60. IEEE, 2017. <a href=\"https://doi.org/10.1109/CVPR.2017.526\">https://doi.org/10.1109/CVPR.2017.526</a>.","ieee":"P. Swoboda, J. Kuske, and B. Savchynskyy, “A dual ascent framework for Lagrangean decomposition of combinatorial problems,” presented at the CVPR: Computer Vision and Pattern Recognition, Honolulu, HA, United States, 2017, vol. 2017, pp. 4950–4960.","ista":"Swoboda P, Kuske J, Savchynskyy B. 2017. A dual ascent framework for Lagrangean decomposition of combinatorial problems. CVPR: Computer Vision and Pattern Recognition vol. 2017, 4950–4960.","mla":"Swoboda, Paul, et al. <i>A Dual Ascent Framework for Lagrangean Decomposition of Combinatorial Problems</i>. Vol. 2017, IEEE, 2017, pp. 4950–60, doi:<a href=\"https://doi.org/10.1109/CVPR.2017.526\">10.1109/CVPR.2017.526</a>.","short":"P. Swoboda, J. Kuske, B. Savchynskyy, in:, IEEE, 2017, pp. 4950–4960."},"publication_status":"published","intvolume":"      2017","month":"07","isi":1,"page":"4950-4960","ec_funded":1,"ddc":["000"],"type":"conference"},{"type":"dissertation","ddc":["581","583","580"],"degree_awarded":"PhD","page":"117","month":"06","pubrep_id":"842","supervisor":[{"last_name":"Friml","id":"4159519E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8302-7596","full_name":"Friml, Jiří","first_name":"Jiří"}],"publication_status":"published","citation":{"ama":"Adamowski M. Investigations into cell polarity and trafficking in the plant model Arabidopsis thaliana . 2017. doi:<a href=\"https://doi.org/10.15479/AT:ISTA:th_842\">10.15479/AT:ISTA:th_842</a>","chicago":"Adamowski, Maciek. “Investigations into Cell Polarity and Trafficking in the Plant Model Arabidopsis Thaliana .” Institute of Science and Technology Austria, 2017. <a href=\"https://doi.org/10.15479/AT:ISTA:th_842\">https://doi.org/10.15479/AT:ISTA:th_842</a>.","apa":"Adamowski, M. (2017). <i>Investigations into cell polarity and trafficking in the plant model Arabidopsis thaliana </i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT:ISTA:th_842\">https://doi.org/10.15479/AT:ISTA:th_842</a>","ista":"Adamowski M. 2017. Investigations into cell polarity and trafficking in the plant model Arabidopsis thaliana . Institute of Science and Technology Austria.","ieee":"M. Adamowski, “Investigations into cell polarity and trafficking in the plant model Arabidopsis thaliana ,” Institute of Science and Technology Austria, 2017.","mla":"Adamowski, Maciek. <i>Investigations into Cell Polarity and Trafficking in the Plant Model Arabidopsis Thaliana </i>. Institute of Science and Technology Austria, 2017, doi:<a href=\"https://doi.org/10.15479/AT:ISTA:th_842\">10.15479/AT:ISTA:th_842</a>.","short":"M. Adamowski, Investigations into Cell Polarity and Trafficking in the Plant Model Arabidopsis Thaliana , Institute of Science and Technology Austria, 2017."},"alternative_title":["ISTA Thesis"],"file":[{"relation":"source_file","file_name":"2017_Adamowski-Thesis_Source.docx","date_updated":"2020-07-14T12:48:15Z","date_created":"2019-04-05T09:03:20Z","file_size":46903863,"creator":"dernst","access_level":"closed","checksum":"193425764d9aaaed3ac57062a867b315","content_type":"application/vnd.openxmlformats-officedocument.wordprocessingml.document","file_id":"6215"},{"relation":"main_file","file_name":"2017_Adamowski-Thesis.pdf","date_updated":"2020-07-14T12:48:15Z","date_created":"2019-04-05T09:03:19Z","file_size":8698888,"creator":"dernst","access_level":"open_access","checksum":"df5ab01be81f821e1b958596a1ec8d21","content_type":"application/pdf","file_id":"6216"}],"file_date_updated":"2020-07-14T12:48:15Z","publisher":"Institute of Science and Technology Austria","department":[{"_id":"JiFr"}],"language":[{"iso":"eng"}],"publist_id":"6483","abstract":[{"text":"The thesis encompasses several topics of plant cell biology which were studied in the model plant Arabidopsis thaliana. Chapter 1 concerns the plant hormone auxin and its polar transport through cells and tissues. The highly controlled, directional transport of auxin is facilitated by plasma membrane-localized transporters. Transporters from the PIN family direct auxin transport due to their polarized localizations at cell membranes. Substantial effort has been put into research on cellular trafficking of PIN proteins, which is thought to underlie their polar distribution. I participated in a forward genetic screen aimed at identifying novel regulators of PIN polarity. The screen yielded several genes which may be involved in PIN polarity regulation or participate in polar auxin transport by other means. Chapter 2 focuses on the endomembrane system, with particular attention to clathrin-mediated endocytosis. The project started with identification of several proteins that interact with clathrin light chains. Among them, I focused on two putative homologues of auxilin, which in non-plant systems is an endocytotic factor known for uncoating clathrin-coated vesicles in the final step of endocytosis. The body of my work consisted of an in-depth characterization of transgenic A. thaliana lines overexpressing these putative auxilins in an inducible manner. Overexpression of these proteins leads to an inhibition of endocytosis, as documented by imaging of cargoes and clathrin-related endocytic machinery. An extension of this work is an investigation into a concept of homeostatic regulation acting between distinct transport processes in the endomembrane system. With auxilin overexpressing lines, where endocytosis is blocked specifically, I made observations on the mutual relationship between two opposite trafficking processes of secretion and endocytosis. In Chapter 3, I analyze cortical microtubule arrays and their relationship to auxin signaling and polarized growth in elongating cells. In plants, microtubules are organized into arrays just below the plasma membrane, and it is thought that their function is to guide membrane-docked cellulose synthase complexes. These, in turn, influence cell wall structure and cell shape by directed deposition of cellulose fibres. In elongating cells, cortical microtubule arrays are able to reorient in relation to long cell axis, and these reorientations have been linked to cell growth and to signaling of growth-regulating factors such as auxin or light. In this chapter, I am addressing the causal relationship between microtubule array reorientation, growth, and auxin signaling. I arrive at a model where array reorientation is not guided by auxin directly, but instead is only controlled by growth, which, in turn, is regulated by auxin.","lang":"eng"}],"related_material":{"record":[{"id":"1591","status":"public","relation":"part_of_dissertation"}]},"_id":"938","date_updated":"2023-09-07T12:06:09Z","title":"Investigations into cell polarity and trafficking in the plant model Arabidopsis thaliana ","article_processing_charge":"No","publication_identifier":{"issn":["2663-337X"]},"oa":1,"has_accepted_license":"1","year":"2017","date_created":"2018-12-11T11:49:18Z","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","doi":"10.15479/AT:ISTA:th_842","status":"public","author":[{"orcid":"0000-0001-6463-5257","full_name":"Adamowski, Maciek","first_name":"Maciek","last_name":"Adamowski","id":"45F536D2-F248-11E8-B48F-1D18A9856A87"}],"oa_version":"Published Version","date_published":"2017-06-02T00:00:00Z","day":"02"},{"publication_status":"published","citation":{"mla":"Midya, Bikashkali, and Vladimir Konotop. “Waveguides with Absorbing Boundaries: Nonlinearity Controlled by an Exceptional Point and Solitons.” <i>Physical Review Letters</i>, vol. 119, no. 3, 033905, American Physical Society, 2017, doi:<a href=\"https://doi.org/10.1103/PhysRevLett.119.033905\">10.1103/PhysRevLett.119.033905</a>.","short":"B. Midya, V. Konotop, Physical Review Letters 119 (2017).","ista":"Midya B, Konotop V. 2017. Waveguides with absorbing boundaries: Nonlinearity controlled by an exceptional point and solitons. Physical Review Letters. 119(3), 033905.","ieee":"B. Midya and V. Konotop, “Waveguides with absorbing boundaries: Nonlinearity controlled by an exceptional point and solitons,” <i>Physical Review Letters</i>, vol. 119, no. 3. American Physical Society, 2017.","chicago":"Midya, Bikashkali, and Vladimir Konotop. “Waveguides with Absorbing Boundaries: Nonlinearity Controlled by an Exceptional Point and Solitons.” <i>Physical Review Letters</i>. American Physical Society, 2017. <a href=\"https://doi.org/10.1103/PhysRevLett.119.033905\">https://doi.org/10.1103/PhysRevLett.119.033905</a>.","apa":"Midya, B., &#38; Konotop, V. (2017). Waveguides with absorbing boundaries: Nonlinearity controlled by an exceptional point and solitons. <i>Physical Review Letters</i>. American Physical Society. <a href=\"https://doi.org/10.1103/PhysRevLett.119.033905\">https://doi.org/10.1103/PhysRevLett.119.033905</a>","ama":"Midya B, Konotop V. Waveguides with absorbing boundaries: Nonlinearity controlled by an exceptional point and solitons. <i>Physical Review Letters</i>. 2017;119(3). doi:<a href=\"https://doi.org/10.1103/PhysRevLett.119.033905\">10.1103/PhysRevLett.119.033905</a>"},"quality_controlled":"1","publisher":"American Physical Society","scopus_import":"1","publication":"Physical Review Letters","abstract":[{"lang":"eng","text":"We reveal the existence of continuous families of guided single-mode solitons in planar waveguides with weakly nonlinear active core and absorbing boundaries. Stable propagation of TE and TM-polarized solitons is accompanied by attenuation of all other modes, i.e., the waveguide features properties of conservative and dissipative systems. If the linear spectrum of the waveguide possesses exceptional points, which occurs in the case of TM polarization, an originally focusing (defocusing) material nonlinearity may become effectively defocusing (focusing). This occurs due to the geometric phase of the carried eigenmode when the surface impedance encircles the exceptional point. In its turn, the change of the effective nonlinearity ensures the existence of dark (bright) solitons in spite of focusing (defocusing) Kerr nonlinearity of the core. The existence of an exceptional point can also result in anomalous enhancement of the effective nonlinearity. In terms of practical applications, the nonlinearity of the reported waveguide can be manipulated by controlling the properties of the absorbing cladding."}],"language":[{"iso":"eng"}],"department":[{"_id":"MiLe"}],"publist_id":"6481","type":"journal_article","main_file_link":[{"url":"https://arxiv.org/abs/1706.04085 ","open_access":"1"}],"ec_funded":1,"issue":"3","article_number":"033905","intvolume":"       119","month":"07","isi":1,"doi":"10.1103/PhysRevLett.119.033905","volume":119,"user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","date_created":"2018-12-11T11:49:18Z","oa_version":"Submitted Version","status":"public","author":[{"id":"456187FC-F248-11E8-B48F-1D18A9856A87","last_name":"Midya","full_name":"Midya, Bikashkali","first_name":"Bikashkali"},{"last_name":"Konotop","full_name":"Konotop, Vladimir","first_name":"Vladimir"}],"day":"18","date_published":"2017-07-18T00:00:00Z","external_id":{"isi":["000405718200012"]},"_id":"939","date_updated":"2023-09-26T15:39:46Z","title":"Waveguides with absorbing boundaries: Nonlinearity controlled by an exceptional point and solitons","article_processing_charge":"No","oa":1,"publication_identifier":{"issn":["00319007"]},"project":[{"grant_number":"291734","call_identifier":"FP7","name":"International IST Postdoc Fellowship Programme","_id":"25681D80-B435-11E9-9278-68D0E5697425"}],"year":"2017"},{"_id":"693","date_updated":"2023-02-23T12:54:57Z","article_processing_charge":"Yes (in subscription journal)","title":"Numbers of presynaptic Ca2+ channel clusters match those of functionally defined vesicular docking sites in single central synapses","publication_identifier":{"issn":["00278424"]},"oa":1,"has_accepted_license":"1","year":"2017","volume":114,"user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","date_created":"2018-12-11T11:47:57Z","pmid":1,"doi":"10.1073/pnas.1704470114","author":[{"full_name":"Miki, Takafumi","first_name":"Takafumi","last_name":"Miki"},{"first_name":"Walter","full_name":"Kaufmann, Walter","orcid":"0000-0001-9735-5315","id":"3F99E422-F248-11E8-B48F-1D18A9856A87","last_name":"Kaufmann"},{"last_name":"Malagon","full_name":"Malagon, Gerardo","first_name":"Gerardo"},{"last_name":"Gomez","first_name":"Laura","full_name":"Gomez, Laura"},{"first_name":"Katsuhiko","full_name":"Tabuchi, Katsuhiko","last_name":"Tabuchi"},{"full_name":"Watanabe, Masahiko","first_name":"Masahiko","last_name":"Watanabe"},{"first_name":"Ryuichi","full_name":"Shigemoto, Ryuichi","orcid":"0000-0001-8761-9444","id":"499F3ABC-F248-11E8-B48F-1D18A9856A87","last_name":"Shigemoto"},{"last_name":"Marty","first_name":"Alain","full_name":"Marty, Alain"}],"status":"public","oa_version":"Published Version","date_published":"2017-06-27T00:00:00Z","day":"27","external_id":{"pmid":["28607047"]},"type":"journal_article","ddc":["570"],"issue":"26","page":"E5246 - E5255","month":"06","intvolume":"       114","publication_status":"published","citation":{"apa":"Miki, T., Kaufmann, W., Malagon, G., Gomez, L., Tabuchi, K., Watanabe, M., … Marty, A. (2017). Numbers of presynaptic Ca2+ channel clusters match those of functionally defined vesicular docking sites in single central synapses. <i>PNAS</i>. National Academy of Sciences. <a href=\"https://doi.org/10.1073/pnas.1704470114\">https://doi.org/10.1073/pnas.1704470114</a>","chicago":"Miki, Takafumi, Walter Kaufmann, Gerardo Malagon, Laura Gomez, Katsuhiko Tabuchi, Masahiko Watanabe, Ryuichi Shigemoto, and Alain Marty. “Numbers of Presynaptic Ca2+ Channel Clusters Match Those of Functionally Defined Vesicular Docking Sites in Single Central Synapses.” <i>PNAS</i>. National Academy of Sciences, 2017. <a href=\"https://doi.org/10.1073/pnas.1704470114\">https://doi.org/10.1073/pnas.1704470114</a>.","ama":"Miki T, Kaufmann W, Malagon G, et al. Numbers of presynaptic Ca2+ channel clusters match those of functionally defined vesicular docking sites in single central synapses. <i>PNAS</i>. 2017;114(26):E5246-E5255. doi:<a href=\"https://doi.org/10.1073/pnas.1704470114\">10.1073/pnas.1704470114</a>","mla":"Miki, Takafumi, et al. “Numbers of Presynaptic Ca2+ Channel Clusters Match Those of Functionally Defined Vesicular Docking Sites in Single Central Synapses.” <i>PNAS</i>, vol. 114, no. 26, National Academy of Sciences, 2017, pp. E5246–55, doi:<a href=\"https://doi.org/10.1073/pnas.1704470114\">10.1073/pnas.1704470114</a>.","short":"T. Miki, W. Kaufmann, G. Malagon, L. Gomez, K. Tabuchi, M. Watanabe, R. Shigemoto, A. Marty, PNAS 114 (2017) E5246–E5255.","ieee":"T. Miki <i>et al.</i>, “Numbers of presynaptic Ca2+ channel clusters match those of functionally defined vesicular docking sites in single central synapses,” <i>PNAS</i>, vol. 114, no. 26. National Academy of Sciences, pp. E5246–E5255, 2017.","ista":"Miki T, Kaufmann W, Malagon G, Gomez L, Tabuchi K, Watanabe M, Shigemoto R, Marty A. 2017. Numbers of presynaptic Ca2+ channel clusters match those of functionally defined vesicular docking sites in single central synapses. PNAS. 114(26), E5246–E5255."},"quality_controlled":"1","file_date_updated":"2020-07-14T12:47:44Z","scopus_import":1,"publication":"PNAS","file":[{"file_id":"7223","access_level":"open_access","creator":"kschuh","checksum":"2ab75d554f3df4a34d20fa8040589b7e","content_type":"application/pdf","date_updated":"2020-07-14T12:47:44Z","file_name":"2017_PNAS_Miki.pdf","file_size":2721544,"date_created":"2020-01-03T13:27:29Z","relation":"main_file"}],"publisher":"National Academy of Sciences","language":[{"iso":"eng"}],"publist_id":"7013","department":[{"_id":"EM-Fac"},{"_id":"RySh"}],"abstract":[{"text":"Many central synapses contain a single presynaptic active zone and a single postsynaptic density. Vesicular release statistics at such “simple synapses” indicate that they contain a small complement of docking sites where vesicles repetitively dock and fuse. In this work, we investigate functional and morphological aspects of docking sites at simple synapses made between cerebellar parallel fibers and molecular layer interneurons. Using immunogold labeling of SDS-treated freeze-fracture replicas, we find that Cav2.1 channels form several clusters per active zone with about nine channels per cluster. The mean value and range of intersynaptic variation are similar for Cav2.1 cluster numbers and for functional estimates of docking-site numbers obtained from the maximum numbers of released vesicles per action potential. Both numbers grow in relation with synaptic size and decrease by a similar extent with age between 2 wk and 4 wk postnatal. Thus, the mean docking-site numbers were 3.15 at 2 wk (range: 1–10) and 2.03 at 4 wk (range: 1–4), whereas the mean numbers of Cav2.1 clusters were 2.84 at 2 wk (range: 1–8) and 2.37 at 4 wk (range: 1–5). These changes were accompanied by decreases of miniature current amplitude (from 93 pA to 56 pA), active-zone surface area (from 0.0427 μm2 to 0.0234 μm2), and initial success rate (from 0.609 to 0.353), indicating a tightening of synaptic transmission with development. Altogether, these results suggest a close correspondence between the number of functionally defined vesicular docking sites and that of clusters of voltage-gated calcium channels. ","lang":"eng"}]},{"publication_status":"published","article_type":"original","citation":{"apa":"Veß, A., Blache, U., Leitner, L., Kurz, A., Ehrenpfordt, A., Sixt, M. K., &#38; Posern, G. (2017). A dual phenotype of MDA MB 468 cancer cells reveals mutual regulation of tensin3 and adhesion plasticity. <i>Journal of Cell Science</i>. Company of Biologists. <a href=\"https://doi.org/10.1242/jcs.200899\">https://doi.org/10.1242/jcs.200899</a>","chicago":"Veß, Astrid, Ulrich Blache, Laura Leitner, Angela Kurz, Anja Ehrenpfordt, Michael K Sixt, and Guido Posern. “A Dual Phenotype of MDA MB 468 Cancer Cells Reveals Mutual Regulation of Tensin3 and Adhesion Plasticity.” <i>Journal of Cell Science</i>. Company of Biologists, 2017. <a href=\"https://doi.org/10.1242/jcs.200899\">https://doi.org/10.1242/jcs.200899</a>.","ama":"Veß A, Blache U, Leitner L, et al. A dual phenotype of MDA MB 468 cancer cells reveals mutual regulation of tensin3 and adhesion plasticity. <i>Journal of Cell Science</i>. 2017;130(13):2172-2184. doi:<a href=\"https://doi.org/10.1242/jcs.200899\">10.1242/jcs.200899</a>","short":"A. Veß, U. Blache, L. Leitner, A. Kurz, A. Ehrenpfordt, M.K. Sixt, G. Posern, Journal of Cell Science 130 (2017) 2172–2184.","mla":"Veß, Astrid, et al. “A Dual Phenotype of MDA MB 468 Cancer Cells Reveals Mutual Regulation of Tensin3 and Adhesion Plasticity.” <i>Journal of Cell Science</i>, vol. 130, no. 13, Company of Biologists, 2017, pp. 2172–84, doi:<a href=\"https://doi.org/10.1242/jcs.200899\">10.1242/jcs.200899</a>.","ieee":"A. Veß <i>et al.</i>, “A dual phenotype of MDA MB 468 cancer cells reveals mutual regulation of tensin3 and adhesion plasticity,” <i>Journal of Cell Science</i>, vol. 130, no. 13. Company of Biologists, pp. 2172–2184, 2017.","ista":"Veß A, Blache U, Leitner L, Kurz A, Ehrenpfordt A, Sixt MK, Posern G. 2017. A dual phenotype of MDA MB 468 cancer cells reveals mutual regulation of tensin3 and adhesion plasticity. Journal of Cell Science. 130(13), 2172–2184."},"quality_controlled":"1","publication":"Journal of Cell Science","scopus_import":1,"file":[{"relation":"main_file","file_name":"2017_CellScience_Vess.pdf","date_updated":"2020-07-14T12:47:45Z","date_created":"2019-10-24T09:43:56Z","file_size":10847596,"creator":"dernst","access_level":"open_access","checksum":"42c81a0a4fc3128883b391c3af3f74bc","content_type":"application/pdf","file_id":"6966"}],"file_date_updated":"2020-07-14T12:47:45Z","publisher":"Company of Biologists","publist_id":"7008","language":[{"iso":"eng"}],"department":[{"_id":"MiSi"}],"abstract":[{"lang":"eng","text":"A change regarding the extent of adhesion - hereafter referred to as adhesion plasticity - between adhesive and less-adhesive states of mammalian cells is important for their behavior. To investigate adhesion plasticity, we have selected a stable isogenic subpopulation of human MDA-MB-468 breast carcinoma cells growing in suspension. These suspension cells are unable to re-adhere to various matrices or to contract three-dimensional collagen lattices. By using transcriptome analysis, we identified the focal adhesion protein tensin3 (Tns3) as a determinant of adhesion plasticity. Tns3 is strongly reduced at mRNA and protein levels in suspension cells. Furthermore, by transiently challenging breast cancer cells to grow under non-adherent conditions markedly reduces Tns3 protein expression, which is regained upon re-adhesion. Stable knockdown of Tns3 in parental MDA-MB-468 cells results in defective adhesion, spreading and migration. Tns3-knockdown cells display impaired structure and dynamics of focal adhesion complexes as determined by immunostaining. Restoration of Tns3 protein expression in suspension cells partially rescues adhesion and focal contact composition. Our work identifies Tns3 as a crucial focal adhesion component regulated by, and functionally contributing to, the switch between adhesive and non-adhesive states in MDA-MB-468 cancer cells."}],"type":"journal_article","ddc":["570"],"issue":"13","page":"2172 - 2184","month":"07","intvolume":"       130","volume":130,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_created":"2018-12-11T11:47:58Z","pmid":1,"doi":"10.1242/jcs.200899","author":[{"last_name":"Veß","full_name":"Veß, Astrid","first_name":"Astrid"},{"first_name":"Ulrich","full_name":"Blache, Ulrich","last_name":"Blache"},{"last_name":"Leitner","full_name":"Leitner, Laura","first_name":"Laura"},{"full_name":"Kurz, Angela","first_name":"Angela","last_name":"Kurz"},{"last_name":"Ehrenpfordt","first_name":"Anja","full_name":"Ehrenpfordt, Anja"},{"first_name":"Michael K","full_name":"Sixt, Michael K","orcid":"0000-0002-6620-9179","id":"41E9FBEA-F248-11E8-B48F-1D18A9856A87","last_name":"Sixt"},{"last_name":"Posern","full_name":"Posern, Guido","first_name":"Guido"}],"status":"public","oa_version":"Published Version","date_published":"2017-07-01T00:00:00Z","day":"01","external_id":{"pmid":["28515231"]},"_id":"694","date_updated":"2021-01-12T08:09:41Z","title":"A dual phenotype of MDA MB 468 cancer cells reveals mutual regulation of tensin3 and adhesion plasticity","publication_identifier":{"issn":["00219533"]},"oa":1,"has_accepted_license":"1","year":"2017"},{"date_published":"2017-07-18T00:00:00Z","day":"18","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"status":"public","author":[{"id":"4342E402-F248-11E8-B48F-1D18A9856A87","last_name":"Lukacisinova","first_name":"Marta","full_name":"Lukacisinova, Marta","orcid":"0000-0002-2519-8004"},{"id":"461468AE-F248-11E8-B48F-1D18A9856A87","last_name":"Novak","full_name":"Novak, Sebastian","first_name":"Sebastian","orcid":"0000-0002-2519-824X"},{"id":"2C5658E6-F248-11E8-B48F-1D18A9856A87","last_name":"Paixao","full_name":"Paixao, Tiago","first_name":"Tiago","orcid":"0000-0003-2361-3953"}],"oa_version":"Published Version","date_created":"2018-12-11T11:47:58Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","volume":13,"doi":"10.1371/journal.pcbi.1005609","has_accepted_license":"1","year":"2017","project":[{"call_identifier":"FP7","grant_number":"618091","_id":"25B1EC9E-B435-11E9-9278-68D0E5697425","name":"Speed of Adaptation in Population Genetics and Evolutionary Computation"}],"publication_identifier":{"issn":["1553734X"]},"oa":1,"title":"Stress induced mutagenesis: Stress diversity facilitates the persistence of mutator genes","related_material":{"record":[{"relation":"research_data","status":"public","id":"9849"},{"relation":"research_data","id":"9850","status":"public"},{"status":"public","relation":"research_data","id":"9851"},{"relation":"research_data","id":"9852","status":"public"},{"relation":"dissertation_contains","status":"public","id":"6263"}]},"date_updated":"2024-03-25T23:30:14Z","_id":"696","department":[{"_id":"ToBo"},{"_id":"NiBa"},{"_id":"CaGu"}],"language":[{"iso":"eng"}],"publist_id":"7004","abstract":[{"text":"Mutator strains are expected to evolve when the availability and effect of beneficial mutations are high enough to counteract the disadvantage from deleterious mutations that will inevitably accumulate. As the population becomes more adapted to its environment, both availability and effect of beneficial mutations necessarily decrease and mutation rates are predicted to decrease. It has been shown that certain molecular mechanisms can lead to increased mutation rates when the organism finds itself in a stressful environment. While this may be a correlated response to other functions, it could also be an adaptive mechanism, raising mutation rates only when it is most advantageous. Here, we use a mathematical model to investigate the plausibility of the adaptive hypothesis. We show that such a mechanism can be mantained if the population is subjected to diverse stresses. By simulating various antibiotic treatment schemes, we find that combination treatments can reduce the effectiveness of second-order selection on stress-induced mutagenesis. We discuss the implications of our results to strategies of antibiotic therapy.","lang":"eng"}],"publication":"PLoS Computational Biology","file_date_updated":"2020-07-14T12:47:46Z","scopus_import":1,"file":[{"date_created":"2018-12-12T10:15:01Z","file_size":3775716,"file_name":"IST-2017-894-v1+1_journal.pcbi.1005609.pdf","date_updated":"2020-07-14T12:47:46Z","relation":"main_file","file_id":"5117","checksum":"9143c290fa6458ed2563bff4b295554a","content_type":"application/pdf","creator":"system","access_level":"open_access"}],"publisher":"Public Library of Science","quality_controlled":"1","citation":{"ieee":"M. Lukacisinova, S. Novak, and T. Paixao, “Stress induced mutagenesis: Stress diversity facilitates the persistence of mutator genes,” <i>PLoS Computational Biology</i>, vol. 13, no. 7. Public Library of Science, 2017.","ista":"Lukacisinova M, Novak S, Paixao T. 2017. Stress induced mutagenesis: Stress diversity facilitates the persistence of mutator genes. PLoS Computational Biology. 13(7), e1005609.","short":"M. Lukacisinova, S. Novak, T. Paixao, PLoS Computational Biology 13 (2017).","mla":"Lukacisinova, Marta, et al. “Stress Induced Mutagenesis: Stress Diversity Facilitates the Persistence of Mutator Genes.” <i>PLoS Computational Biology</i>, vol. 13, no. 7, e1005609, Public Library of Science, 2017, doi:<a href=\"https://doi.org/10.1371/journal.pcbi.1005609\">10.1371/journal.pcbi.1005609</a>.","ama":"Lukacisinova M, Novak S, Paixao T. Stress induced mutagenesis: Stress diversity facilitates the persistence of mutator genes. <i>PLoS Computational Biology</i>. 2017;13(7). doi:<a href=\"https://doi.org/10.1371/journal.pcbi.1005609\">10.1371/journal.pcbi.1005609</a>","chicago":"Lukacisinova, Marta, Sebastian Novak, and Tiago Paixao. “Stress Induced Mutagenesis: Stress Diversity Facilitates the Persistence of Mutator Genes.” <i>PLoS Computational Biology</i>. Public Library of Science, 2017. <a href=\"https://doi.org/10.1371/journal.pcbi.1005609\">https://doi.org/10.1371/journal.pcbi.1005609</a>.","apa":"Lukacisinova, M., Novak, S., &#38; Paixao, T. (2017). Stress induced mutagenesis: Stress diversity facilitates the persistence of mutator genes. <i>PLoS Computational Biology</i>. Public Library of Science. <a href=\"https://doi.org/10.1371/journal.pcbi.1005609\">https://doi.org/10.1371/journal.pcbi.1005609</a>"},"publication_status":"published","license":"https://creativecommons.org/licenses/by/4.0/","article_type":"original","month":"07","pubrep_id":"894","intvolume":"        13","article_number":"e1005609","issue":"7","ec_funded":1,"ddc":["576"],"type":"journal_article"},{"month":"07","article_number":"39","intvolume":"        80","pubrep_id":"893","ec_funded":1,"type":"conference","ddc":["005"],"department":[{"_id":"KrPi"}],"language":[{"iso":"eng"}],"publist_id":"7003","abstract":[{"lang":"eng","text":"De, Trevisan and Tulsiani [CRYPTO 2010] show that every distribution over n-bit strings which has constant statistical distance to uniform (e.g., the output of a pseudorandom generator mapping n-1 to n bit strings), can be distinguished from the uniform distribution with advantage epsilon by a circuit of size O( 2^n epsilon^2). We generalize this result, showing that a distribution which has less than k bits of min-entropy, can be distinguished from any distribution with k bits of delta-smooth min-entropy with advantage epsilon by a circuit of size O(2^k epsilon^2/delta^2). As a special case, this implies that any distribution with support at most 2^k (e.g., the output of a pseudoentropy generator mapping k to n bit strings) can be distinguished from any given distribution with min-entropy k+1 with advantage epsilon by a circuit of size O(2^k epsilon^2). Our result thus shows that pseudoentropy distributions face basically the same non-uniform attacks as pseudorandom distributions. "}],"scopus_import":1,"file_date_updated":"2020-07-14T12:47:46Z","file":[{"file_id":"4701","access_level":"open_access","creator":"system","content_type":"application/pdf","checksum":"e95618a001692f1af2d68f5fde43bc1f","date_updated":"2020-07-14T12:47:46Z","file_name":"IST-2017-893-v1+1_LIPIcs-ICALP-2017-39.pdf","file_size":601004,"date_created":"2018-12-12T10:08:40Z","relation":"main_file"}],"publisher":"Schloss Dagstuhl - Leibniz-Zentrum für Informatik","citation":{"mla":"Pietrzak, Krzysztof Z., and Maciej Skórski. <i>Non Uniform Attacks against Pseudoentropy</i>. Vol. 80, 39, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2017, doi:<a href=\"https://doi.org/10.4230/LIPIcs.ICALP.2017.39\">10.4230/LIPIcs.ICALP.2017.39</a>.","short":"K.Z. Pietrzak, M. Skórski, in:, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2017.","ista":"Pietrzak KZ, Skórski M. 2017. Non uniform attacks against pseudoentropy. ICALP: International Colloquium on Automata, Languages, and Programming, LIPIcs, vol. 80, 39.","ieee":"K. Z. Pietrzak and M. Skórski, “Non uniform attacks against pseudoentropy,” presented at the ICALP: International Colloquium on Automata, Languages, and Programming, Warsaw, Poland, 2017, vol. 80.","apa":"Pietrzak, K. Z., &#38; Skórski, M. (2017). Non uniform attacks against pseudoentropy (Vol. 80). Presented at the ICALP: International Colloquium on Automata, Languages, and Programming, Warsaw, Poland: Schloss Dagstuhl - Leibniz-Zentrum für Informatik. <a href=\"https://doi.org/10.4230/LIPIcs.ICALP.2017.39\">https://doi.org/10.4230/LIPIcs.ICALP.2017.39</a>","chicago":"Pietrzak, Krzysztof Z, and Maciej Skórski. “Non Uniform Attacks against Pseudoentropy,” Vol. 80. Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2017. <a href=\"https://doi.org/10.4230/LIPIcs.ICALP.2017.39\">https://doi.org/10.4230/LIPIcs.ICALP.2017.39</a>.","ama":"Pietrzak KZ, Skórski M. Non uniform attacks against pseudoentropy. In: Vol 80. Schloss Dagstuhl - Leibniz-Zentrum für Informatik; 2017. doi:<a href=\"https://doi.org/10.4230/LIPIcs.ICALP.2017.39\">10.4230/LIPIcs.ICALP.2017.39</a>"},"alternative_title":["LIPIcs"],"quality_controlled":"1","publication_status":"published","has_accepted_license":"1","project":[{"_id":"258AA5B2-B435-11E9-9278-68D0E5697425","name":"Teaching Old Crypto New Tricks","call_identifier":"H2020","grant_number":"682815"}],"year":"2017","publication_identifier":{"issn":["18688969"]},"oa":1,"title":"Non uniform attacks against pseudoentropy","conference":{"name":"ICALP: International Colloquium on Automata, Languages, and Programming","location":"Warsaw, Poland","end_date":"2017-07-14","start_date":"2017-07-10"},"_id":"697","date_updated":"2021-01-12T08:11:15Z","date_published":"2017-07-01T00:00:00Z","day":"01","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"author":[{"first_name":"Krzysztof Z","full_name":"Pietrzak, Krzysztof Z","orcid":"0000-0002-9139-1654","id":"3E04A7AA-F248-11E8-B48F-1D18A9856A87","last_name":"Pietrzak"},{"last_name":"Skórski","id":"EC09FA6A-02D0-11E9-8223-86B7C91467DD","first_name":"Maciej","full_name":"Skórski, Maciej"}],"status":"public","oa_version":"Published Version","volume":80,"user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","date_created":"2018-12-11T11:47:59Z","doi":"10.4230/LIPIcs.ICALP.2017.39"},{"publication_identifier":{"issn":["10591524"]},"oa":1,"has_accepted_license":"1","project":[{"call_identifier":"FWF","grant_number":"Y 903-N35","_id":"2530CA10-B435-11E9-9278-68D0E5697425","name":"Gaussian Graphical Models: Theory and Applications"}],"year":"2017","date_updated":"2021-01-12T08:11:17Z","_id":"698","title":"Orientation and repositioning of chromosomes correlate with cell geometry dependent gene expression","date_published":"2017-07-07T00:00:00Z","day":"07","date_created":"2018-12-11T11:47:59Z","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","volume":28,"doi":"10.1091/mbc.E16-12-0825","author":[{"first_name":"Yejun","full_name":"Wang, Yejun","last_name":"Wang"},{"full_name":"Nagarajan, Mallika","first_name":"Mallika","last_name":"Nagarajan"},{"id":"49ADD78E-F248-11E8-B48F-1D18A9856A87","last_name":"Uhler","full_name":"Uhler, Caroline","first_name":"Caroline","orcid":"0000-0002-7008-0216"},{"last_name":"Shivashankar","full_name":"Shivashankar, Gv","first_name":"Gv"}],"tmp":{"image":"/images/cc_by_nc_sa.png","legal_code_url":"https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode","name":"Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)","short":"CC BY-NC-SA (4.0)"},"status":"public","oa_version":"Published Version","issue":"14","page":"1997 - 2009","month":"07","intvolume":"        28","pubrep_id":"892","ddc":["519"],"type":"journal_article","file_date_updated":"2020-07-14T12:47:46Z","scopus_import":1,"publication":"Molecular Biology of the Cell","file":[{"creator":"system","access_level":"open_access","content_type":"application/pdf","checksum":"de01dac9e30970cfa6ae902480a4e04d","file_id":"4844","relation":"main_file","file_name":"IST-2017-892-v1+1_Mol._Biol._Cell-2017-Wang-1997-2009.pdf","date_updated":"2020-07-14T12:47:46Z","file_size":1086097,"date_created":"2018-12-12T10:10:53Z"}],"publisher":"American Society for Cell Biology","department":[{"_id":"CaUh"}],"language":[{"iso":"eng"}],"publist_id":"7001","abstract":[{"text":"Extracellular matrix signals from the microenvironment regulate gene expression patterns and cell behavior. Using a combination of experiments and geometric models, we demonstrate correlations between cell geometry, three-dimensional (3D) organization of chromosome territories, and gene expression. Fluorescence in situ hybridization experiments showed that micropatterned fibroblasts cultured on anisotropic versus isotropic substrates resulted in repositioning of specific chromosomes, which contained genes that were differentially regulated by cell geometries. Experiments combined with ellipsoid packing models revealed that the mechanosensitivity of chromosomes was correlated with their orientation in the nucleus. Transcription inhibition experiments suggested that the intermingling degree was more sensitive to global changes in transcription than to chromosome radial positioning and its orientations. These results suggested that cell geometry modulated 3D chromosome arrangement, and their neighborhoods correlated with gene expression patterns in a predictable manner. This is central to understanding geometric control of genetic programs involved in cellular homeostasis and the associated diseases. ","lang":"eng"}],"publication_status":"published","license":"https://creativecommons.org/licenses/by-nc-sa/4.0/","quality_controlled":"1","citation":{"ama":"Wang Y, Nagarajan M, Uhler C, Shivashankar G. Orientation and repositioning of chromosomes correlate with cell geometry dependent gene expression. <i>Molecular Biology of the Cell</i>. 2017;28(14):1997-2009. doi:<a href=\"https://doi.org/10.1091/mbc.E16-12-0825\">10.1091/mbc.E16-12-0825</a>","apa":"Wang, Y., Nagarajan, M., Uhler, C., &#38; Shivashankar, G. (2017). Orientation and repositioning of chromosomes correlate with cell geometry dependent gene expression. <i>Molecular Biology of the Cell</i>. American Society for Cell Biology. <a href=\"https://doi.org/10.1091/mbc.E16-12-0825\">https://doi.org/10.1091/mbc.E16-12-0825</a>","chicago":"Wang, Yejun, Mallika Nagarajan, Caroline Uhler, and Gv Shivashankar. “Orientation and Repositioning of Chromosomes Correlate with Cell Geometry Dependent Gene Expression.” <i>Molecular Biology of the Cell</i>. American Society for Cell Biology, 2017. <a href=\"https://doi.org/10.1091/mbc.E16-12-0825\">https://doi.org/10.1091/mbc.E16-12-0825</a>.","ista":"Wang Y, Nagarajan M, Uhler C, Shivashankar G. 2017. Orientation and repositioning of chromosomes correlate with cell geometry dependent gene expression. Molecular Biology of the Cell. 28(14), 1997–2009.","ieee":"Y. Wang, M. Nagarajan, C. Uhler, and G. Shivashankar, “Orientation and repositioning of chromosomes correlate with cell geometry dependent gene expression,” <i>Molecular Biology of the Cell</i>, vol. 28, no. 14. American Society for Cell Biology, pp. 1997–2009, 2017.","short":"Y. Wang, M. Nagarajan, C. Uhler, G. Shivashankar, Molecular Biology of the Cell 28 (2017) 1997–2009.","mla":"Wang, Yejun, et al. “Orientation and Repositioning of Chromosomes Correlate with Cell Geometry Dependent Gene Expression.” <i>Molecular Biology of the Cell</i>, vol. 28, no. 14, American Society for Cell Biology, 2017, pp. 1997–2009, doi:<a href=\"https://doi.org/10.1091/mbc.E16-12-0825\">10.1091/mbc.E16-12-0825</a>."}},{"main_file_link":[{"open_access":"1","url":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502615/"}],"type":"journal_article","intvolume":"       114","month":"07","page":"E5396 - E5405","issue":"27","quality_controlled":"1","citation":{"ieee":"C. Veller, L. Hayward, M. Nowak, and C. Hilbe, “The red queen and king in finite populations,” <i>PNAS</i>, vol. 114, no. 27. National Academy of Sciences, pp. E5396–E5405, 2017.","ista":"Veller C, Hayward L, Nowak M, Hilbe C. 2017. The red queen and king in finite populations. PNAS. 114(27), E5396–E5405.","short":"C. Veller, L. Hayward, M. Nowak, C. Hilbe, PNAS 114 (2017) E5396–E5405.","mla":"Veller, Carl, et al. “The Red Queen and King in Finite Populations.” <i>PNAS</i>, vol. 114, no. 27, National Academy of Sciences, 2017, pp. E5396–405, doi:<a href=\"https://doi.org/10.1073/pnas.1702020114\">10.1073/pnas.1702020114</a>.","ama":"Veller C, Hayward L, Nowak M, Hilbe C. The red queen and king in finite populations. <i>PNAS</i>. 2017;114(27):E5396-E5405. doi:<a href=\"https://doi.org/10.1073/pnas.1702020114\">10.1073/pnas.1702020114</a>","apa":"Veller, C., Hayward, L., Nowak, M., &#38; Hilbe, C. (2017). The red queen and king in finite populations. <i>PNAS</i>. National Academy of Sciences. <a href=\"https://doi.org/10.1073/pnas.1702020114\">https://doi.org/10.1073/pnas.1702020114</a>","chicago":"Veller, Carl, Laura Hayward, Martin Nowak, and Christian Hilbe. “The Red Queen and King in Finite Populations.” <i>PNAS</i>. National Academy of Sciences, 2017. <a href=\"https://doi.org/10.1073/pnas.1702020114\">https://doi.org/10.1073/pnas.1702020114</a>."},"publication_status":"published","abstract":[{"text":"In antagonistic symbioses, such as host–parasite interactions, one population’s success is the other’s loss. In mutualistic symbioses, such as division of labor, both parties can gain, but they might have different preferences over the possible mutualistic arrangements. The rates of evolution of the two populations in a symbiosis are important determinants of which population will be more successful: Faster evolution is thought to be favored in antagonistic symbioses (the “Red Queen effect”), but disfavored in certain mutualistic symbioses (the “Red King effect”). However, it remains unclear which biological parameters drive these effects. Here, we analyze the effects of the various determinants of evolutionary rate: generation time, mutation rate, population size, and the intensity of natural selection. Our main results hold for the case where mutation is infrequent. Slower evolution causes a long-term advantage in an important class of mutualistic interactions. Surprisingly, less intense selection is the strongest driver of this Red King effect, whereas relative mutation rates and generation times have little effect. In antagonistic interactions, faster evolution by any means is beneficial. Our results provide insight into the demographic evolution of symbionts. ","lang":"eng"}],"publist_id":"7002","department":[{"_id":"KrCh"}],"language":[{"iso":"eng"}],"publisher":"National Academy of Sciences","publication":"PNAS","scopus_import":1,"title":"The red queen and king in finite populations","date_updated":"2021-01-12T08:11:21Z","_id":"699","year":"2017","oa":1,"publication_identifier":{"issn":["00278424"]},"oa_version":"Submitted Version","status":"public","author":[{"first_name":"Carl","full_name":"Veller, Carl","last_name":"Veller"},{"last_name":"Hayward","first_name":"Laura","full_name":"Hayward, Laura"},{"first_name":"Martin","full_name":"Nowak, Martin","last_name":"Nowak"},{"id":"2FDF8F3C-F248-11E8-B48F-1D18A9856A87","last_name":"Hilbe","full_name":"Hilbe, Christian","first_name":"Christian","orcid":"0000-0001-5116-955X"}],"pmid":1,"doi":"10.1073/pnas.1702020114","date_created":"2018-12-11T11:48:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","volume":114,"external_id":{"pmid":["28630336"]},"day":"03","date_published":"2017-07-03T00:00:00Z"},{"month":"07","article_number":"012404","intvolume":"        96","issue":"1","ec_funded":1,"main_file_link":[{"url":"https://arxiv.org/pdf/1612.07061.pdf","open_access":"1"}],"type":"journal_article","publist_id":"6997","department":[{"_id":"JoFi"}],"language":[{"iso":"eng"}],"abstract":[{"lang":"eng","text":"Microtubules provide the mechanical force required for chromosome separation during mitosis. However, little is known about the dynamic (high-frequency) mechanical properties of microtubules. Here, we theoretically propose to control the vibrations of a doubly clamped microtubule by tip electrodes and to detect its motion via the optomechanical coupling between the vibrational modes of the microtubule and an optical cavity. In the presence of a red-detuned strong pump laser, this coupling leads to optomechanical-induced transparency of an optical probe field, which can be detected with state-of-the art technology. The center frequency and line width of the transparency peak give the resonance frequency and damping rate of the microtubule, respectively, while the height of the peak reveals information about the microtubule-cavity field coupling. Our method opens the new possibilities to gain information about the physical properties of microtubules, which will enhance our capability to design physical cancer treatment protocols as alternatives to chemotherapeutic drugs."}],"scopus_import":1,"publication":" Physical Review E Statistical Nonlinear and Soft Matter Physics ","publisher":"American Institute of Physics","citation":{"ieee":"S. Barzanjeh, V. Salari, J. Tuszynski, M. Cifra, and C. Simon, “Optomechanical proposal for monitoring microtubule mechanical vibrations,” <i> Physical Review E Statistical Nonlinear and Soft Matter Physics </i>, vol. 96, no. 1. American Institute of Physics, 2017.","ista":"Barzanjeh S, Salari V, Tuszynski J, Cifra M, Simon C. 2017. Optomechanical proposal for monitoring microtubule mechanical vibrations.  Physical Review E Statistical Nonlinear and Soft Matter Physics . 96(1), 012404.","short":"S. Barzanjeh, V. Salari, J. Tuszynski, M. Cifra, C. Simon,  Physical Review E Statistical Nonlinear and Soft Matter Physics  96 (2017).","mla":"Barzanjeh, Shabir, et al. “Optomechanical Proposal for Monitoring Microtubule Mechanical Vibrations.” <i> Physical Review E Statistical Nonlinear and Soft Matter Physics </i>, vol. 96, no. 1, 012404, American Institute of Physics, 2017, doi:<a href=\"https://doi.org/10.1103/PhysRevE.96.012404\">10.1103/PhysRevE.96.012404</a>.","ama":"Barzanjeh S, Salari V, Tuszynski J, Cifra M, Simon C. Optomechanical proposal for monitoring microtubule mechanical vibrations. <i> Physical Review E Statistical Nonlinear and Soft Matter Physics </i>. 2017;96(1). doi:<a href=\"https://doi.org/10.1103/PhysRevE.96.012404\">10.1103/PhysRevE.96.012404</a>","apa":"Barzanjeh, S., Salari, V., Tuszynski, J., Cifra, M., &#38; Simon, C. (2017). Optomechanical proposal for monitoring microtubule mechanical vibrations. <i> Physical Review E Statistical Nonlinear and Soft Matter Physics </i>. American Institute of Physics. <a href=\"https://doi.org/10.1103/PhysRevE.96.012404\">https://doi.org/10.1103/PhysRevE.96.012404</a>","chicago":"Barzanjeh, Shabir, Vahid Salari, Jack Tuszynski, Michal Cifra, and Christoph Simon. “Optomechanical Proposal for Monitoring Microtubule Mechanical Vibrations.” <i> Physical Review E Statistical Nonlinear and Soft Matter Physics </i>. American Institute of Physics, 2017. <a href=\"https://doi.org/10.1103/PhysRevE.96.012404\">https://doi.org/10.1103/PhysRevE.96.012404</a>."},"quality_controlled":"1","publication_status":"published","project":[{"call_identifier":"H2020","grant_number":"707438","_id":"258047B6-B435-11E9-9278-68D0E5697425","name":"Microwave-to-Optical Quantum Link: Quantum Teleportation and Quantum Illumination with cavity Optomechanics"}],"year":"2017","publication_identifier":{"issn":["24700045"]},"oa":1,"title":"Optomechanical proposal for monitoring microtubule mechanical vibrations","_id":"700","date_updated":"2023-02-23T12:56:35Z","date_published":"2017-07-12T00:00:00Z","day":"12","author":[{"orcid":"0000-0003-0415-1423","full_name":"Barzanjeh, Shabir","first_name":"Shabir","last_name":"Barzanjeh","id":"2D25E1F6-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Salari","first_name":"Vahid","full_name":"Salari, Vahid"},{"full_name":"Tuszynski, Jack","first_name":"Jack","last_name":"Tuszynski"},{"last_name":"Cifra","first_name":"Michal","full_name":"Cifra, Michal"},{"first_name":"Christoph","full_name":"Simon, Christoph","last_name":"Simon"}],"status":"public","oa_version":"Submitted Version","volume":96,"date_created":"2018-12-11T11:48:00Z","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","doi":"10.1103/PhysRevE.96.012404"},{"oa_version":"Submitted Version","author":[{"full_name":"Kynčl, Jan","first_name":"Jan","last_name":"Kynčl"},{"full_name":"Patakova, Zuzana","first_name":"Zuzana","orcid":"0000-0002-3975-1683","id":"48B57058-F248-11E8-B48F-1D18A9856A87","last_name":"Patakova"}],"status":"public","volume":24,"date_created":"2018-12-11T11:48:00Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","day":"14","date_published":"2017-07-14T00:00:00Z","title":"On the nonexistence of k reptile simplices in ℝ^3 and ℝ^4","_id":"701","date_updated":"2021-01-12T08:11:28Z","year":"2017","has_accepted_license":"1","oa":1,"publication_identifier":{"issn":["10778926"]},"citation":{"mla":"Kynčl, Jan, and Zuzana Patakova. “On the Nonexistence of k Reptile Simplices in ℝ^3 and ℝ^4.” <i>The Electronic Journal of Combinatorics</i>, vol. 24, no. 3, International Press, 2017, pp. 1–44.","short":"J. Kynčl, Z. Patakova, The Electronic Journal of Combinatorics 24 (2017) 1–44.","ista":"Kynčl J, Patakova Z. 2017. On the nonexistence of k reptile simplices in ℝ^3 and ℝ^4. The Electronic Journal of Combinatorics. 24(3), 1–44.","ieee":"J. Kynčl and Z. Patakova, “On the nonexistence of k reptile simplices in ℝ^3 and ℝ^4,” <i>The Electronic Journal of Combinatorics</i>, vol. 24, no. 3. International Press, pp. 1–44, 2017.","apa":"Kynčl, J., &#38; Patakova, Z. (2017). On the nonexistence of k reptile simplices in ℝ^3 and ℝ^4. <i>The Electronic Journal of Combinatorics</i>. International Press.","chicago":"Kynčl, Jan, and Zuzana Patakova. “On the Nonexistence of k Reptile Simplices in ℝ^3 and ℝ^4.” <i>The Electronic Journal of Combinatorics</i>. International Press, 2017.","ama":"Kynčl J, Patakova Z. On the nonexistence of k reptile simplices in ℝ^3 and ℝ^4. <i>The Electronic Journal of Combinatorics</i>. 2017;24(3):1-44."},"quality_controlled":"1","publication_status":"published","abstract":[{"lang":"eng","text":"A d-dimensional simplex S is called a k-reptile (or a k-reptile simplex) if it can be tiled by k simplices with disjoint interiors that are all mutually congruent and similar to S. For d = 2, triangular k-reptiles exist for all k of the form a^2, 3a^2 or a^2+b^2 and they have been completely characterized by Snover, Waiveris, and Williams. On the other hand, the only k-reptile simplices that are known for d ≥ 3, have k = m^d, where m is a positive integer. We substantially simplify the proof by Matoušek and the second author that for d = 3, k-reptile tetrahedra can exist only for k = m^3. We then prove a weaker analogue of this result for d = 4 by showing that four-dimensional k-reptile simplices can exist only for k = m^2."}],"department":[{"_id":"UlWa"}],"language":[{"iso":"eng"}],"publist_id":"6996","publisher":"International Press","publication":"The Electronic Journal of Combinatorics","file_date_updated":"2020-07-14T12:47:47Z","file":[{"relation":"main_file","file_size":544042,"date_created":"2018-12-12T10:14:25Z","date_updated":"2020-07-14T12:47:47Z","file_name":"IST-2018-984-v1+1_Patakova_on_the_nonexistence_of_k-reptile_simplices_in_R_3_and_R_4_2017.pdf","content_type":"application/pdf","checksum":"a431e573e31df13bc0f66de3061006ec","access_level":"open_access","creator":"system","file_id":"5077"}],"type":"journal_article","ddc":["500"],"pubrep_id":"984","intvolume":"        24","month":"07","page":"1-44","issue":"3"},{"doi":"10.1126/scitranslmed.aao0972","volume":9,"date_created":"2018-12-11T11:48:01Z","publication_status":"published","user_id":"4435EBFC-F248-11E8-B48F-1D18A9856A87","oa_version":"None","citation":{"apa":"Novarino, G. (2017). The riddle of CHD8 haploinsufficiency in autism spectrum disorder. <i>Science Translational Medicine</i>. American Association for the Advancement of Science. <a href=\"https://doi.org/10.1126/scitranslmed.aao0972\">https://doi.org/10.1126/scitranslmed.aao0972</a>","chicago":"Novarino, Gaia. “The Riddle of CHD8 Haploinsufficiency in Autism Spectrum Disorder.” <i>Science Translational Medicine</i>. American Association for the Advancement of Science, 2017. <a href=\"https://doi.org/10.1126/scitranslmed.aao0972\">https://doi.org/10.1126/scitranslmed.aao0972</a>.","ama":"Novarino G. The riddle of CHD8 haploinsufficiency in autism spectrum disorder. <i>Science Translational Medicine</i>. 2017;9(399):eaao0972. doi:<a href=\"https://doi.org/10.1126/scitranslmed.aao0972\">10.1126/scitranslmed.aao0972</a>","short":"G. Novarino, Science Translational Medicine 9 (2017) eaao0972.","mla":"Novarino, Gaia. “The Riddle of CHD8 Haploinsufficiency in Autism Spectrum Disorder.” <i>Science Translational Medicine</i>, vol. 9, no. 399, American Association for the Advancement of Science, 2017, p. eaao0972, doi:<a href=\"https://doi.org/10.1126/scitranslmed.aao0972\">10.1126/scitranslmed.aao0972</a>.","ista":"Novarino G. 2017. The riddle of CHD8 haploinsufficiency in autism spectrum disorder. Science Translational Medicine. 9(399), eaao0972.","ieee":"G. Novarino, “The riddle of CHD8 haploinsufficiency in autism spectrum disorder,” <i>Science Translational Medicine</i>, vol. 9, no. 399. American Association for the Advancement of Science, p. eaao0972, 2017."},"author":[{"orcid":"0000-0002-7673-7178","full_name":"Novarino, Gaia","first_name":"Gaia","last_name":"Novarino","id":"3E57A680-F248-11E8-B48F-1D18A9856A87"}],"status":"public","quality_controlled":"1","publisher":"American Association for the Advancement of Science","day":"19","scopus_import":1,"publication":"Science Translational Medicine","date_published":"2017-07-19T00:00:00Z","abstract":[{"text":"Leading autism-associated mutation in mouse partially mimics human disorder.\r\n\r\n","lang":"eng"}],"publist_id":"6993","language":[{"iso":"eng"}],"department":[{"_id":"GaNo"}],"type":"journal_article","_id":"702","date_updated":"2021-01-12T08:11:31Z","title":"The riddle of CHD8 haploinsufficiency in autism spectrum disorder","page":"eaao0972","issue":"399","publication_identifier":{"issn":["19466234"]},"intvolume":"         9","year":"2017","month":"07"},{"article_number":"e25100","intvolume":"         6","pubrep_id":"890","month":"07","type":"journal_article","ddc":["576"],"publisher":"eLife Sciences Publications","publication":"eLife","file_date_updated":"2020-07-14T12:47:48Z","scopus_import":1,"file":[{"relation":"main_file","date_created":"2018-12-12T10:12:54Z","file_size":2092088,"file_name":"IST-2017-890-v1+1_elife-25100-v1.pdf","date_updated":"2020-07-14T12:47:48Z","content_type":"application/pdf","checksum":"6b908b5db9f61f6820ebd7f8fa815571","creator":"system","access_level":"open_access","file_id":"4975"},{"checksum":"ca21530389b720243552678125fdba35","content_type":"application/pdf","creator":"system","access_level":"open_access","file_id":"4976","relation":"main_file","date_created":"2018-12-12T10:12:55Z","file_size":3428681,"file_name":"IST-2017-890-v1+2_elife-25100-figures-v1.pdf","date_updated":"2020-07-14T12:47:48Z"}],"abstract":[{"text":"How the organization of genes on a chromosome shapes adaptation is essential for understanding evolutionary paths. Here, we investigate how adaptation to rapidly increasing levels of antibiotic depends on the chromosomal neighborhood of a drug-resistance gene inserted at different positions of the Escherichia coli chromosome. Using a dual-fluorescence reporter that allows us to distinguish gene amplifications from other up-mutations, we track in real-time adaptive changes in expression of the drug-resistance gene. We find that the relative contribution of several mutation types differs systematically between loci due to properties of neighboring genes: essentiality, expression, orientation, termination, and presence of duplicates. These properties determine rate and fitness effects of gene amplification, deletions, and mutations compromising transcriptional termination. Thus, the adaptive potential of a gene under selection is a system-property with a complex genetic basis that is specific for each chromosomal locus, and it can be inferred from detailed functional and genomic data.","lang":"eng"}],"department":[{"_id":"CaGu"}],"publist_id":"6990","language":[{"iso":"eng"}],"publication_status":"published","citation":{"mla":"Steinrück, Magdalena, and Calin C. Guet. “Complex Chromosomal Neighborhood Effects Determine the Adaptive Potential of a Gene under Selection.” <i>ELife</i>, vol. 6, e25100, eLife Sciences Publications, 2017, doi:<a href=\"https://doi.org/10.7554/eLife.25100\">10.7554/eLife.25100</a>.","short":"M. Steinrück, C.C. Guet, ELife 6 (2017).","ista":"Steinrück M, Guet CC. 2017. Complex chromosomal neighborhood effects determine the adaptive potential of a gene under selection. eLife. 6, e25100.","ieee":"M. Steinrück and C. C. Guet, “Complex chromosomal neighborhood effects determine the adaptive potential of a gene under selection,” <i>eLife</i>, vol. 6. eLife Sciences Publications, 2017.","chicago":"Steinrück, Magdalena, and Calin C Guet. “Complex Chromosomal Neighborhood Effects Determine the Adaptive Potential of a Gene under Selection.” <i>ELife</i>. eLife Sciences Publications, 2017. <a href=\"https://doi.org/10.7554/eLife.25100\">https://doi.org/10.7554/eLife.25100</a>.","apa":"Steinrück, M., &#38; Guet, C. C. (2017). Complex chromosomal neighborhood effects determine the adaptive potential of a gene under selection. <i>ELife</i>. eLife Sciences Publications. <a href=\"https://doi.org/10.7554/eLife.25100\">https://doi.org/10.7554/eLife.25100</a>","ama":"Steinrück M, Guet CC. Complex chromosomal neighborhood effects determine the adaptive potential of a gene under selection. <i>eLife</i>. 2017;6. doi:<a href=\"https://doi.org/10.7554/eLife.25100\">10.7554/eLife.25100</a>"},"quality_controlled":"1","oa":1,"publication_identifier":{"issn":["2050084X"]},"year":"2017","has_accepted_license":"1","_id":"704","date_updated":"2024-03-25T23:30:14Z","related_material":{"record":[{"relation":"popular_science","id":"5564","status":"public"},{"id":"26","status":"public","relation":"dissertation_contains"}]},"title":"Complex chromosomal neighborhood effects determine the adaptive potential of a gene under selection","day":"25","date_published":"2017-07-25T00:00:00Z","doi":"10.7554/eLife.25100","volume":6,"date_created":"2018-12-11T11:48:01Z","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","oa_version":"Published Version","author":[{"full_name":"Steinrück, Magdalena","first_name":"Magdalena","orcid":"0000-0003-1229-9719","id":"2C023F40-F248-11E8-B48F-1D18A9856A87","last_name":"Steinrück"},{"first_name":"Calin C","full_name":"Guet, Calin C","orcid":"0000-0001-6220-2052","id":"47F8433E-F248-11E8-B48F-1D18A9856A87","last_name":"Guet"}],"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"status":"public"},{"date_updated":"2021-01-12T08:11:37Z","_id":"706","type":"journal_article","title":"Roles of afadin in functional differentiations of hippocampal mossy fiber synapse","publication_identifier":{"issn":["13569597"]},"issue":"8","page":"715 - 722","month":"08","year":"2017","intvolume":"        22","publication_status":"published","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","date_created":"2018-12-11T11:48:02Z","volume":22,"doi":"10.1111/gtc.12508","quality_controlled":"1","author":[{"id":"3395256A-F248-11E8-B48F-1D18A9856A87","last_name":"Geng","first_name":"Xiaoqi","full_name":"Geng, Xiaoqi"},{"last_name":"Maruo","first_name":"Tomohiko","full_name":"Maruo, Tomohiko"},{"last_name":"Mandai","first_name":"Kenji","full_name":"Mandai, Kenji"},{"last_name":"Supriyanto","full_name":"Supriyanto, Irwan","first_name":"Irwan"},{"full_name":"Miyata, Muneaki","first_name":"Muneaki","last_name":"Miyata"},{"first_name":"Shotaro","full_name":"Sakakibara, Shotaro","last_name":"Sakakibara"},{"last_name":"Mizoguchi","first_name":"Akira","full_name":"Mizoguchi, Akira"},{"full_name":"Takai, Yoshimi","first_name":"Yoshimi","last_name":"Takai"},{"last_name":"Mori","first_name":"Masahiro","full_name":"Mori, Masahiro"}],"status":"public","citation":{"ama":"Geng X, Maruo T, Mandai K, et al. Roles of afadin in functional differentiations of hippocampal mossy fiber synapse. <i>Genes to Cells</i>. 2017;22(8):715-722. doi:<a href=\"https://doi.org/10.1111/gtc.12508\">10.1111/gtc.12508</a>","apa":"Geng, X., Maruo, T., Mandai, K., Supriyanto, I., Miyata, M., Sakakibara, S., … Mori, M. (2017). Roles of afadin in functional differentiations of hippocampal mossy fiber synapse. <i>Genes to Cells</i>. Wiley-Blackwell. <a href=\"https://doi.org/10.1111/gtc.12508\">https://doi.org/10.1111/gtc.12508</a>","chicago":"Geng, Xiaoqi, Tomohiko Maruo, Kenji Mandai, Irwan Supriyanto, Muneaki Miyata, Shotaro Sakakibara, Akira Mizoguchi, Yoshimi Takai, and Masahiro Mori. “Roles of Afadin in Functional Differentiations of Hippocampal Mossy Fiber Synapse.” <i>Genes to Cells</i>. Wiley-Blackwell, 2017. <a href=\"https://doi.org/10.1111/gtc.12508\">https://doi.org/10.1111/gtc.12508</a>.","ieee":"X. Geng <i>et al.</i>, “Roles of afadin in functional differentiations of hippocampal mossy fiber synapse,” <i>Genes to Cells</i>, vol. 22, no. 8. Wiley-Blackwell, pp. 715–722, 2017.","ista":"Geng X, Maruo T, Mandai K, Supriyanto I, Miyata M, Sakakibara S, Mizoguchi A, Takai Y, Mori M. 2017. Roles of afadin in functional differentiations of hippocampal mossy fiber synapse. Genes to Cells. 22(8), 715–722.","mla":"Geng, Xiaoqi, et al. “Roles of Afadin in Functional Differentiations of Hippocampal Mossy Fiber Synapse.” <i>Genes to Cells</i>, vol. 22, no. 8, Wiley-Blackwell, 2017, pp. 715–22, doi:<a href=\"https://doi.org/10.1111/gtc.12508\">10.1111/gtc.12508</a>.","short":"X. Geng, T. Maruo, K. Mandai, I. Supriyanto, M. Miyata, S. Sakakibara, A. Mizoguchi, Y. Takai, M. Mori, Genes to Cells 22 (2017) 715–722."},"oa_version":"None","date_published":"2017-08-01T00:00:00Z","publication":"Genes to Cells","scopus_import":1,"publisher":"Wiley-Blackwell","day":"01","language":[{"iso":"eng"}],"department":[{"_id":"PeJo"}],"publist_id":"6987","abstract":[{"text":"A hippocampal mossy fiber synapse has a complex structure and is implicated in learning and memory. In this synapse, the mossy fiber boutons attach to the dendritic shaft by puncta adherentia junctions and wrap around a multiply-branched spine, forming synaptic junctions. We have recently shown using transmission electron microscopy, immunoelectron microscopy and serial block face-scanning electron microscopy that atypical puncta adherentia junctions are formed in the afadin-deficient mossy fiber synapse and that the complexity of postsynaptic spines and mossy fiber boutons, the number of spine heads, the area of postsynaptic densities and the density of synaptic vesicles docked to active zones are decreased in the afadin-deficient synapse. We investigated here the roles of afadin in the functional differentiations of the mossy fiber synapse using the afadin-deficient mice. The electrophysiological studies showed that both the release probability of glutamate and the postsynaptic responsiveness to glutamate were markedly reduced, but not completely lost, in the afadin-deficient mossy fiber synapse, whereas neither long-term potentiation nor long-term depression was affected. These results indicate that afadin plays roles in the functional differentiations of the presynapse and the postsynapse of the hippocampal mossy fiber synapse.","lang":"eng"}]},{"oa_version":"Preprint","status":"public","author":[{"last_name":"Akopyan","id":"430D2C90-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-2548-617X","full_name":"Akopyan, Arseniy","first_name":"Arseniy"},{"last_name":"Karasev","first_name":"Roman","full_name":"Karasev, Roman"}],"doi":"10.1112/blms.12062","date_created":"2018-12-11T11:48:02Z","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","volume":49,"day":"01","date_published":"2017-08-01T00:00:00Z","title":"A tight estimate for the waist of the ball ","date_updated":"2021-01-12T08:11:41Z","_id":"707","year":"2017","project":[{"grant_number":"291734","call_identifier":"FP7","name":"International IST Postdoc Fellowship Programme","_id":"25681D80-B435-11E9-9278-68D0E5697425"}],"oa":1,"publication_identifier":{"issn":["00246093"]},"quality_controlled":"1","citation":{"chicago":"Akopyan, Arseniy, and Roman Karasev. “A Tight Estimate for the Waist of the Ball .” <i>Bulletin of the London Mathematical Society</i>. Wiley-Blackwell, 2017. <a href=\"https://doi.org/10.1112/blms.12062\">https://doi.org/10.1112/blms.12062</a>.","apa":"Akopyan, A., &#38; Karasev, R. (2017). A tight estimate for the waist of the ball . <i>Bulletin of the London Mathematical Society</i>. Wiley-Blackwell. <a href=\"https://doi.org/10.1112/blms.12062\">https://doi.org/10.1112/blms.12062</a>","ama":"Akopyan A, Karasev R. A tight estimate for the waist of the ball . <i>Bulletin of the London Mathematical Society</i>. 2017;49(4):690-693. doi:<a href=\"https://doi.org/10.1112/blms.12062\">10.1112/blms.12062</a>","short":"A. Akopyan, R. Karasev, Bulletin of the London Mathematical Society 49 (2017) 690–693.","mla":"Akopyan, Arseniy, and Roman Karasev. “A Tight Estimate for the Waist of the Ball .” <i>Bulletin of the London Mathematical Society</i>, vol. 49, no. 4, Wiley-Blackwell, 2017, pp. 690–93, doi:<a href=\"https://doi.org/10.1112/blms.12062\">10.1112/blms.12062</a>.","ieee":"A. Akopyan and R. Karasev, “A tight estimate for the waist of the ball ,” <i>Bulletin of the London Mathematical Society</i>, vol. 49, no. 4. Wiley-Blackwell, pp. 690–693, 2017.","ista":"Akopyan A, Karasev R. 2017. A tight estimate for the waist of the ball . Bulletin of the London Mathematical Society. 49(4), 690–693."},"publication_status":"published","abstract":[{"lang":"eng","text":"We answer a question of M. Gromov on the waist of the unit ball."}],"language":[{"iso":"eng"}],"publist_id":"6982","department":[{"_id":"HeEd"}],"publisher":"Wiley-Blackwell","scopus_import":1,"publication":"Bulletin of the London Mathematical Society","main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/1608.06279"}],"type":"journal_article","intvolume":"        49","month":"08","page":"690 - 693","ec_funded":1,"issue":"4"},{"citation":{"short":"B. Nagy, A. Hovhannisyan, R. Barzan, T. Chen, M. Kukley, PLoS Biology 15 (2017).","mla":"Nagy, Balint, et al. “Different Patterns of Neuronal Activity Trigger Distinct Responses of Oligodendrocyte Precursor Cells in the Corpus Callosum.” <i>PLoS Biology</i>, vol. 15, no. 8, e2001993, Public Library of Science, 2017, doi:<a href=\"https://doi.org/10.1371/journal.pbio.2001993\">10.1371/journal.pbio.2001993</a>.","ista":"Nagy B, Hovhannisyan A, Barzan R, Chen T, Kukley M. 2017. Different patterns of neuronal activity trigger distinct responses of oligodendrocyte precursor cells in the corpus callosum. PLoS Biology. 15(8), e2001993.","ieee":"B. Nagy, A. Hovhannisyan, R. Barzan, T. Chen, and M. Kukley, “Different patterns of neuronal activity trigger distinct responses of oligodendrocyte precursor cells in the corpus callosum,” <i>PLoS Biology</i>, vol. 15, no. 8. Public Library of Science, 2017.","chicago":"Nagy, Balint, Anahit Hovhannisyan, Ruxandra Barzan, Ting Chen, and Maria Kukley. “Different Patterns of Neuronal Activity Trigger Distinct Responses of Oligodendrocyte Precursor Cells in the Corpus Callosum.” <i>PLoS Biology</i>. Public Library of Science, 2017. <a href=\"https://doi.org/10.1371/journal.pbio.2001993\">https://doi.org/10.1371/journal.pbio.2001993</a>.","apa":"Nagy, B., Hovhannisyan, A., Barzan, R., Chen, T., &#38; Kukley, M. (2017). Different patterns of neuronal activity trigger distinct responses of oligodendrocyte precursor cells in the corpus callosum. <i>PLoS Biology</i>. Public Library of Science. <a href=\"https://doi.org/10.1371/journal.pbio.2001993\">https://doi.org/10.1371/journal.pbio.2001993</a>","ama":"Nagy B, Hovhannisyan A, Barzan R, Chen T, Kukley M. Different patterns of neuronal activity trigger distinct responses of oligodendrocyte precursor cells in the corpus callosum. <i>PLoS Biology</i>. 2017;15(8). doi:<a href=\"https://doi.org/10.1371/journal.pbio.2001993\">10.1371/journal.pbio.2001993</a>"},"quality_controlled":"1","publication_status":"published","publist_id":"6983","language":[{"iso":"eng"}],"department":[{"_id":"SaSi"}],"abstract":[{"lang":"eng","text":"In the developing and adult brain, oligodendrocyte precursor cells (OPCs) are influenced by neuronal activity: they are involved in synaptic signaling with neurons, and their proliferation and differentiation into myelinating glia can be altered by transient changes in neuronal firing. An important question that has been unanswered is whether OPCs can discriminate different patterns of neuronal activity and respond to them in a distinct way. Here, we demonstrate in brain slices that the pattern of neuronal activity determines the functional changes triggered at synapses between axons and OPCs. Furthermore, we show that stimulation of the corpus callosum at different frequencies in vivo affects proliferation and differentiation of OPCs in a dissimilar way. Our findings suggest that neurons do not influence OPCs in “all-or-none” fashion but use their firing pattern to tune the response and behavior of these nonneuronal cells."}],"file":[{"relation":"main_file","file_size":18155365,"date_created":"2018-12-12T10:15:35Z","date_updated":"2020-07-14T12:47:49Z","file_name":"IST-2017-889-v1+1_journal.pbio.2001993.pdf","content_type":"application/pdf","checksum":"0c974f430682dc832ea7b27ab5a93124","access_level":"open_access","creator":"system","file_id":"5156"}],"file_date_updated":"2020-07-14T12:47:49Z","scopus_import":1,"publication":"PLoS Biology","publisher":"Public Library of Science","type":"journal_article","ddc":["576","610"],"month":"08","article_number":"e2001993","pubrep_id":"889","intvolume":"        15","issue":"8","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"author":[{"full_name":"Nagy, Balint","first_name":"Balint","orcid":"0000-0002-4002-4686","id":"30F830CE-02D1-11E9-9BAA-DAF4881429F2","last_name":"Nagy"},{"full_name":"Hovhannisyan, Anahit","first_name":"Anahit","last_name":"Hovhannisyan"},{"last_name":"Barzan","first_name":"Ruxandra","full_name":"Barzan, Ruxandra"},{"full_name":"Chen, Ting","first_name":"Ting","last_name":"Chen"},{"first_name":"Maria","full_name":"Kukley, Maria","last_name":"Kukley"}],"status":"public","oa_version":"Published Version","volume":15,"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","date_created":"2018-12-11T11:48:03Z","doi":"10.1371/journal.pbio.2001993","date_published":"2017-08-22T00:00:00Z","day":"22","title":"Different patterns of neuronal activity trigger distinct responses of oligodendrocyte precursor cells in the corpus callosum","_id":"708","date_updated":"2021-01-12T08:11:45Z","has_accepted_license":"1","year":"2017","publication_identifier":{"issn":["15449173"]},"oa":1},{"title":"Gene expression changes of thermo sensitive transient receptor potential channels in obese mice","date_updated":"2021-01-12T08:11:47Z","_id":"709","type":"journal_article","intvolume":"        41","year":"2017","month":"08","page":"908 - 913","publication_identifier":{"issn":["10656995"]},"issue":"8","oa_version":"None","author":[{"first_name":"Wuping","full_name":"Sun, Wuping","last_name":"Sun"},{"first_name":"Chen","full_name":"Li, Chen","last_name":"Li"},{"last_name":"Zhang","first_name":"Yonghong","full_name":"Zhang, Yonghong"},{"last_name":"Jiang","first_name":"Changyu","full_name":"Jiang, Changyu"},{"full_name":"Zhai, Ming-Zhu","first_name":"Ming-Zhu","last_name":"Zhai","id":"34009CFA-F248-11E8-B48F-1D18A9856A87"},{"first_name":"Qian","full_name":"Zhou, Qian","last_name":"Zhou"},{"first_name":"Lizu","full_name":"Xiao, Lizu","last_name":"Xiao"},{"first_name":"Qiwen","full_name":"Deng, Qiwen","last_name":"Deng"}],"status":"public","quality_controlled":"1","citation":{"chicago":"Sun, Wuping, Chen Li, Yonghong Zhang, Changyu Jiang, Ming-Zhu Zhai, Qian Zhou, Lizu Xiao, and Qiwen Deng. “Gene Expression Changes of Thermo Sensitive Transient Receptor Potential Channels in Obese Mice.” <i>Cell Biology International</i>. Wiley-Blackwell, 2017. <a href=\"https://doi.org/10.1002/cbin.10783\">https://doi.org/10.1002/cbin.10783</a>.","apa":"Sun, W., Li, C., Zhang, Y., Jiang, C., Zhai, M.-Z., Zhou, Q., … Deng, Q. (2017). Gene expression changes of thermo sensitive transient receptor potential channels in obese mice. <i>Cell Biology International</i>. Wiley-Blackwell. <a href=\"https://doi.org/10.1002/cbin.10783\">https://doi.org/10.1002/cbin.10783</a>","ama":"Sun W, Li C, Zhang Y, et al. Gene expression changes of thermo sensitive transient receptor potential channels in obese mice. <i>Cell Biology International</i>. 2017;41(8):908-913. doi:<a href=\"https://doi.org/10.1002/cbin.10783\">10.1002/cbin.10783</a>","short":"W. Sun, C. Li, Y. Zhang, C. Jiang, M.-Z. Zhai, Q. Zhou, L. Xiao, Q. Deng, Cell Biology International 41 (2017) 908–913.","mla":"Sun, Wuping, et al. “Gene Expression Changes of Thermo Sensitive Transient Receptor Potential Channels in Obese Mice.” <i>Cell Biology International</i>, vol. 41, no. 8, Wiley-Blackwell, 2017, pp. 908–13, doi:<a href=\"https://doi.org/10.1002/cbin.10783\">10.1002/cbin.10783</a>.","ieee":"W. Sun <i>et al.</i>, “Gene expression changes of thermo sensitive transient receptor potential channels in obese mice,” <i>Cell Biology International</i>, vol. 41, no. 8. Wiley-Blackwell, pp. 908–913, 2017.","ista":"Sun W, Li C, Zhang Y, Jiang C, Zhai M-Z, Zhou Q, Xiao L, Deng Q. 2017. Gene expression changes of thermo sensitive transient receptor potential channels in obese mice. Cell Biology International. 41(8), 908–913."},"doi":"10.1002/cbin.10783","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","publication_status":"published","date_created":"2018-12-11T11:48:04Z","volume":41,"abstract":[{"lang":"eng","text":"Adipose tissues play key roles in energy homeostasis. Brown adipocytes and beige adipocytes in white adipose tissue (WAT) share the similar characters of thermogenesis, both of them could be potential targets for obesity management. Several thermo-sensitive transient receptor potential channels (thermoTRPs) are shown to be involved in adipocyte biology. However, the expression pattern of thermoTRPs in adipose tissues from obese mice is still unknown. The mRNA expression of thermoTRPs in subcutaneous WAT (sWAT) and interscapular brown adipose tissue (iBAT) from lean and obese mice were measured using reverse transcriptase-quantitative PCRs (RT-qPCR). The results demonstrated that all 10 thermoTRPs are expressed in both iBAT and sWAT, and without significant difference in the mRNA expression level of thermoTRPs between these two tissues. Moreover, Trpv1 and Trpv3 mRNA expression levels in both iBAT and sWAT were significantly decreased in high fat diet (HFD)-induced obese mice and db/db (leptin receptor deficient) mice. Trpm2 mRNA expression level was significantly decreased only in sWAT from HFD-induced obese mice and db/db mice. On the other hand, Trpv2 and Trpv4 mRNA expression levels in iBAT and sWAT were significantly increased in HFD-induced obese mice and db/db mice. Taken together, we conclude that all 10 thermoTRPs are expressed in iBAT and sWAT. And several thermoTRPs differentially expressed in adipose tissues from HFD-induced obese mice and db/db mice, suggesting a potential involvement in anti-obesity regulations."}],"language":[{"iso":"eng"}],"department":[{"_id":"RySh"}],"publist_id":"6981","publisher":"Wiley-Blackwell","day":"01","date_published":"2017-08-01T00:00:00Z","publication":"Cell Biology International","scopus_import":1},{"citation":{"ama":"Obremski M, Skórski M. Renyi entropy estimation revisited. In: Vol 81. Schloss Dagstuhl - Leibniz-Zentrum für Informatik; 2017. doi:<a href=\"https://doi.org/10.4230/LIPIcs.APPROX-RANDOM.2017.20\">10.4230/LIPIcs.APPROX-RANDOM.2017.20</a>","chicago":"Obremski, Maciej, and Maciej Skórski. “Renyi Entropy Estimation Revisited,” Vol. 81. Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2017. <a href=\"https://doi.org/10.4230/LIPIcs.APPROX-RANDOM.2017.20\">https://doi.org/10.4230/LIPIcs.APPROX-RANDOM.2017.20</a>.","apa":"Obremski, M., &#38; Skórski, M. (2017). Renyi entropy estimation revisited (Vol. 81). Presented at the 20th International Workshop on Approximation Algorithms for Combinatorial Optimization Problems, APPROX, Berkeley, USA: Schloss Dagstuhl - Leibniz-Zentrum für Informatik. <a href=\"https://doi.org/10.4230/LIPIcs.APPROX-RANDOM.2017.20\">https://doi.org/10.4230/LIPIcs.APPROX-RANDOM.2017.20</a>","ista":"Obremski M, Skórski M. 2017. Renyi entropy estimation revisited. 20th International Workshop on Approximation Algorithms for Combinatorial Optimization Problems, APPROX, LIPIcs, vol. 81, 20.","ieee":"M. Obremski and M. Skórski, “Renyi entropy estimation revisited,” presented at the 20th International Workshop on Approximation Algorithms for Combinatorial Optimization Problems, APPROX, Berkeley, USA, 2017, vol. 81.","short":"M. Obremski, M. Skórski, in:, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2017.","mla":"Obremski, Maciej, and Maciej Skórski. <i>Renyi Entropy Estimation Revisited</i>. Vol. 81, 20, Schloss Dagstuhl - Leibniz-Zentrum für Informatik, 2017, doi:<a href=\"https://doi.org/10.4230/LIPIcs.APPROX-RANDOM.2017.20\">10.4230/LIPIcs.APPROX-RANDOM.2017.20</a>."},"quality_controlled":"1","alternative_title":["LIPIcs"],"publication_status":"published","abstract":[{"lang":"eng","text":"We revisit the problem of estimating entropy of discrete distributions from independent samples, studied recently by Acharya, Orlitsky, Suresh and Tyagi (SODA 2015), improving their upper and lower bounds on the necessary sample size n. For estimating Renyi entropy of order alpha, up to constant accuracy and error probability, we show the following * Upper bounds n = O(1) 2^{(1-1/alpha)H_alpha} for integer alpha&gt;1, as the worst case over distributions with Renyi entropy equal to H_alpha. * Lower bounds n = Omega(1) K^{1-1/alpha} for any real alpha&gt;1, with the constant being an inverse polynomial of the accuracy, as the worst case over all distributions on K elements. Our upper bounds essentially replace the alphabet size by a factor exponential in the entropy, which offers improvements especially in low or medium entropy regimes (interesting for example in anomaly detection). As for the lower bounds, our proof explicitly shows how the complexity depends on both alphabet and accuracy, partially solving the open problem posted in previous works. The argument for upper bounds derives a clean identity for the variance of falling-power sum of a multinomial distribution. Our approach for lower bounds utilizes convex optimization to find a distribution with possibly worse estimation performance, and may be of independent interest as a tool to work with Le Cam’s two point method. "}],"language":[{"iso":"eng"}],"publist_id":"6979","department":[{"_id":"KrPi"}],"publisher":"Schloss Dagstuhl - Leibniz-Zentrum für Informatik","file_date_updated":"2020-07-14T12:47:49Z","scopus_import":1,"file":[{"file_id":"4991","checksum":"89225c7dcec2c93838458c9102858985","content_type":"application/pdf","access_level":"open_access","creator":"system","file_size":604813,"date_created":"2018-12-12T10:13:10Z","date_updated":"2020-07-14T12:47:49Z","file_name":"IST-2017-888-v1+1_LIPIcs-APPROX-RANDOM-2017-20.pdf","relation":"main_file"}],"type":"conference","ddc":["005","600"],"article_number":"20","pubrep_id":"888","intvolume":"        81","month":"08","ec_funded":1,"oa_version":"Published Version","author":[{"first_name":"Maciej","full_name":"Obremski, Maciej","last_name":"Obremski"},{"full_name":"Skórski, Maciej","first_name":"Maciej","last_name":"Skórski","id":"EC09FA6A-02D0-11E9-8223-86B7C91467DD"}],"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","image":"/images/cc_by.png","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)"},"status":"public","doi":"10.4230/LIPIcs.APPROX-RANDOM.2017.20","volume":81,"date_created":"2018-12-11T11:48:04Z","user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","day":"01","date_published":"2017-08-01T00:00:00Z","title":"Renyi entropy estimation revisited","_id":"710","date_updated":"2021-01-12T08:11:50Z","conference":{"start_date":"2017-08-18","end_date":"2017-08-18","name":"20th International Workshop on Approximation Algorithms for Combinatorial Optimization Problems, APPROX","location":"Berkeley, USA"},"project":[{"_id":"258AA5B2-B435-11E9-9278-68D0E5697425","name":"Teaching Old Crypto New Tricks","call_identifier":"H2020","grant_number":"682815"}],"year":"2017","has_accepted_license":"1","oa":1,"publication_identifier":{"issn":["18688969"]}}]