[{"publisher":"American Association for the Advancement of Science","oa_version":"None","user_id":"4435EBFC-F248-11E8-B48F-1D18A9856A87","department":[{"_id":"GaNo"}],"publist_id":"7365","date_published":"2018-01-10T00:00:00Z","publication_status":"published","citation":{"ama":"Novarino G. Zika-associated microcephaly: Reduce the stress and race for the treatment. <i>Science Translational Medicine</i>. 2018;10(423). doi:<a href=\"https://doi.org/10.1126/scitranslmed.aar7514\">10.1126/scitranslmed.aar7514</a>","apa":"Novarino, G. (2018). Zika-associated microcephaly: Reduce the stress and race for the treatment. <i>Science Translational Medicine</i>. American Association for the Advancement of Science. <a href=\"https://doi.org/10.1126/scitranslmed.aar7514\">https://doi.org/10.1126/scitranslmed.aar7514</a>","chicago":"Novarino, Gaia. “Zika-Associated Microcephaly: Reduce the Stress and Race for the Treatment.” <i>Science Translational Medicine</i>. American Association for the Advancement of Science, 2018. <a href=\"https://doi.org/10.1126/scitranslmed.aar7514\">https://doi.org/10.1126/scitranslmed.aar7514</a>.","ieee":"G. Novarino, “Zika-associated microcephaly: Reduce the stress and race for the treatment,” <i>Science Translational Medicine</i>, vol. 10, no. 423. American Association for the Advancement of Science, 2018.","short":"G. Novarino, Science Translational Medicine 10 (2018).","mla":"Novarino, Gaia. “Zika-Associated Microcephaly: Reduce the Stress and Race for the Treatment.” <i>Science Translational Medicine</i>, vol. 10, no. 423, eaar7514, American Association for the Advancement of Science, 2018, doi:<a href=\"https://doi.org/10.1126/scitranslmed.aar7514\">10.1126/scitranslmed.aar7514</a>.","ista":"Novarino G. 2018. Zika-associated microcephaly: Reduce the stress and race for the treatment. Science Translational Medicine. 10(423), eaar7514."},"abstract":[{"lang":"eng","text":"Inhibition of the endoplasmic reticulum stress pathway may hold the key to Zika virus-associated microcephaly treatment. "}],"_id":"456","quality_controlled":"1","language":[{"iso":"eng"}],"author":[{"first_name":"Gaia","full_name":"Novarino, Gaia","last_name":"Novarino","id":"3E57A680-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-7673-7178"}],"month":"01","type":"journal_article","status":"public","intvolume":"        10","scopus_import":1,"publication":"Science Translational Medicine","date_updated":"2021-01-12T07:59:42Z","article_number":"eaar7514","doi":"10.1126/scitranslmed.aar7514","day":"10","volume":10,"title":"Zika-associated microcephaly: Reduce the stress and race for the treatment","issue":"423","year":"2018","date_created":"2018-12-11T11:46:34Z"},{"publication_status":"published","citation":{"chicago":"Pleska, Maros, Moritz Lang, Dominik Refardt, Bruce Levin, and Calin C Guet. “Phage-Host Population Dynamics Promotes Prophage Acquisition in Bacteria with Innate Immunity.” <i>Nature Ecology and Evolution</i>. Springer Nature, 2018. <a href=\"https://doi.org/10.1038/s41559-017-0424-z\">https://doi.org/10.1038/s41559-017-0424-z</a>.","apa":"Pleska, M., Lang, M., Refardt, D., Levin, B., &#38; Guet, C. C. (2018). Phage-host population dynamics promotes prophage acquisition in bacteria with innate immunity. <i>Nature Ecology and Evolution</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41559-017-0424-z\">https://doi.org/10.1038/s41559-017-0424-z</a>","ama":"Pleska M, Lang M, Refardt D, Levin B, Guet CC. Phage-host population dynamics promotes prophage acquisition in bacteria with innate immunity. <i>Nature Ecology and Evolution</i>. 2018;2(2):359-366. doi:<a href=\"https://doi.org/10.1038/s41559-017-0424-z\">10.1038/s41559-017-0424-z</a>","ista":"Pleska M, Lang M, Refardt D, Levin B, Guet CC. 2018. Phage-host population dynamics promotes prophage acquisition in bacteria with innate immunity. Nature Ecology and Evolution. 2(2), 359–366.","mla":"Pleska, Maros, et al. “Phage-Host Population Dynamics Promotes Prophage Acquisition in Bacteria with Innate Immunity.” <i>Nature Ecology and Evolution</i>, vol. 2, no. 2, Springer Nature, 2018, pp. 359–66, doi:<a href=\"https://doi.org/10.1038/s41559-017-0424-z\">10.1038/s41559-017-0424-z</a>.","short":"M. Pleska, M. Lang, D. Refardt, B. Levin, C.C. Guet, Nature Ecology and Evolution 2 (2018) 359–366.","ieee":"M. Pleska, M. Lang, D. Refardt, B. Levin, and C. C. Guet, “Phage-host population dynamics promotes prophage acquisition in bacteria with innate immunity,” <i>Nature Ecology and Evolution</i>, vol. 2, no. 2. Springer Nature, pp. 359–366, 2018."},"quality_controlled":"1","department":[{"_id":"CaGu"},{"_id":"GaTk"}],"oa_version":"None","date_published":"2018-02-01T00:00:00Z","title":"Phage-host population dynamics promotes prophage acquisition in bacteria with innate immunity","issue":"2","doi":"10.1038/s41559-017-0424-z","day":"01","isi":1,"year":"2018","external_id":{"isi":["000426516400027"]},"date_updated":"2023-09-15T12:04:57Z","intvolume":"         2","status":"public","abstract":[{"lang":"eng","text":"Temperate bacteriophages integrate in bacterial genomes as prophages and represent an important source of genetic variation for bacterial evolution, frequently transmitting fitness-augmenting genes such as toxins responsible for virulence of major pathogens. However, only a fraction of bacteriophage infections are lysogenic and lead to prophage acquisition, whereas the majority are lytic and kill the infected bacteria. Unless able to discriminate lytic from lysogenic infections, mechanisms of immunity to bacteriophages are expected to act as a double-edged sword and increase the odds of survival at the cost of depriving bacteria of potentially beneficial prophages. We show that although restriction-modification systems as mechanisms of innate immunity prevent both lytic and lysogenic infections indiscriminately in individual bacteria, they increase the number of prophage-acquiring individuals at the population level. We find that this counterintuitive result is a consequence of phage-host population dynamics, in which restriction-modification systems delay infection onset until bacteria reach densities at which the probability of lysogeny increases. These results underscore the importance of population-level dynamics as a key factor modulating costs and benefits of immunity to temperate bacteriophages"}],"_id":"457","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","project":[{"grant_number":"291734","call_identifier":"FP7","_id":"25681D80-B435-11E9-9278-68D0E5697425","name":"International IST Postdoc Fellowship Programme"},{"name":"Multi-Level Conflicts in Evolutionary Dynamics of Restriction-Modification Systems (HFSP Young investigators' grant)","_id":"251BCBEC-B435-11E9-9278-68D0E5697425","grant_number":"RGY0079/2011"},{"name":"Effects of Stochasticity on the Function of Restriction-Modi cation Systems at the Single-Cell Level (DOC Fellowship)","_id":"251D65D8-B435-11E9-9278-68D0E5697425","grant_number":"24210"}],"publisher":"Springer Nature","ec_funded":1,"publist_id":"7364","related_material":{"record":[{"relation":"dissertation_contains","id":"202","status":"public"}]},"volume":2,"page":"359 - 366","date_created":"2018-12-11T11:46:35Z","type":"journal_article","author":[{"last_name":"Pleska","full_name":"Pleska, Maros","first_name":"Maros","id":"4569785E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-7460-7479"},{"full_name":"Lang, Moritz","first_name":"Moritz","last_name":"Lang","id":"29E0800A-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Refardt","full_name":"Refardt, Dominik","first_name":"Dominik"},{"full_name":"Levin, Bruce","first_name":"Bruce","last_name":"Levin"},{"full_name":"Guet, Calin C","first_name":"Calin C","last_name":"Guet","orcid":"0000-0001-6220-2052","id":"47F8433E-F248-11E8-B48F-1D18A9856A87"}],"month":"02","language":[{"iso":"eng"}],"publication":"Nature Ecology and Evolution","article_processing_charge":"No","scopus_import":"1"},{"oa":1,"external_id":{"isi":["000423197800019"]},"date_updated":"2023-09-11T14:19:12Z","intvolume":"       370","status":"public","title":"Incircular nets and confocal conics","issue":"4","day":"01","doi":"10.1090/tran/7292","isi":1,"year":"2018","department":[{"_id":"HeEd"}],"oa_version":"Preprint","date_published":"2018-04-01T00:00:00Z","citation":{"ama":"Akopyan A, Bobenko A. Incircular nets and confocal conics. <i>Transactions of the American Mathematical Society</i>. 2018;370(4):2825-2854. doi:<a href=\"https://doi.org/10.1090/tran/7292\">10.1090/tran/7292</a>","apa":"Akopyan, A., &#38; Bobenko, A. (2018). Incircular nets and confocal conics. <i>Transactions of the American Mathematical Society</i>. American Mathematical Society. <a href=\"https://doi.org/10.1090/tran/7292\">https://doi.org/10.1090/tran/7292</a>","chicago":"Akopyan, Arseniy, and Alexander Bobenko. “Incircular Nets and Confocal Conics.” <i>Transactions of the American Mathematical Society</i>. American Mathematical Society, 2018. <a href=\"https://doi.org/10.1090/tran/7292\">https://doi.org/10.1090/tran/7292</a>.","ieee":"A. Akopyan and A. Bobenko, “Incircular nets and confocal conics,” <i>Transactions of the American Mathematical Society</i>, vol. 370, no. 4. American Mathematical Society, pp. 2825–2854, 2018.","short":"A. Akopyan, A. Bobenko, Transactions of the American Mathematical Society 370 (2018) 2825–2854.","mla":"Akopyan, Arseniy, and Alexander Bobenko. “Incircular Nets and Confocal Conics.” <i>Transactions of the American Mathematical Society</i>, vol. 370, no. 4, American Mathematical Society, 2018, pp. 2825–54, doi:<a href=\"https://doi.org/10.1090/tran/7292\">10.1090/tran/7292</a>.","ista":"Akopyan A, Bobenko A. 2018. Incircular nets and confocal conics. Transactions of the American Mathematical Society. 370(4), 2825–2854."},"publication_status":"published","quality_controlled":"1","type":"journal_article","language":[{"iso":"eng"}],"month":"04","author":[{"orcid":"0000-0002-2548-617X","id":"430D2C90-F248-11E8-B48F-1D18A9856A87","first_name":"Arseniy","full_name":"Akopyan, Arseniy","last_name":"Akopyan"},{"last_name":"Bobenko","full_name":"Bobenko, Alexander","first_name":"Alexander"}],"publication":"Transactions of the American Mathematical Society","article_processing_charge":"No","scopus_import":"1","volume":370,"page":"2825 - 2854","date_created":"2018-12-11T11:46:35Z","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","project":[{"grant_number":"291734","call_identifier":"FP7","_id":"25681D80-B435-11E9-9278-68D0E5697425","name":"International IST Postdoc Fellowship Programme"}],"main_file_link":[{"url":"https://arxiv.org/abs/1602.04637","open_access":"1"}],"publisher":"American Mathematical Society","ec_funded":1,"publist_id":"7363","abstract":[{"lang":"eng","text":"We consider congruences of straight lines in a plane with the combinatorics of the square grid, with all elementary quadrilaterals possessing an incircle. It is shown that all the vertices of such nets (we call them incircular or IC-nets) lie on confocal conics. Our main new results are on checkerboard IC-nets in the plane. These are congruences of straight lines in the plane with the combinatorics of the square grid, combinatorially colored as a checkerboard, such that all black coordinate quadrilaterals possess inscribed circles. We show how this larger class of IC-nets appears quite naturally in Laguerre geometry of oriented planes and spheres and leads to new remarkable incidence theorems. Most of our results are valid in hyperbolic and spherical geometries as well. We present also generalizations in spaces of higher dimension, called checkerboard IS-nets. The construction of these nets is based on a new 9 inspheres incidence theorem."}],"acknowledgement":"DFG Collaborative Research Center TRR 109 “Discretization in Geometry and Dynamics”; People Programme (Marie Curie Actions) of the European Union’s Seventh Framework Programme (FP7/2007-2013) REA grant agreement n◦[291734]","_id":"458"},{"article_processing_charge":"No","publication":"Physical Review B","scopus_import":"1","author":[{"full_name":"Hetterich, Daniel","first_name":"Daniel","last_name":"Hetterich"},{"first_name":"Norman","full_name":"Yao, Norman","last_name":"Yao"},{"first_name":"Maksym","full_name":"Serbyn, Maksym","last_name":"Serbyn","orcid":"0000-0002-2399-5827","id":"47809E7E-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Pollmann, Frank","first_name":"Frank","last_name":"Pollmann"},{"first_name":"Björn","full_name":"Trauzettel, Björn","last_name":"Trauzettel"}],"language":[{"iso":"eng"}],"month":"10","type":"journal_article","date_created":"2018-12-11T11:44:20Z","volume":98,"publist_id":"8008","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","publisher":"American Physical Society","main_file_link":[{"open_access":"1","url":"https://arxiv.org/abs/1806.08316"}],"_id":"46","acknowledgement":"F.P. acknowledges the sup- port of the DFG Research Unit FOR 1807 through Grants No. PO 1370/2-1 and No. TRR80, the Nanosystems Initiative Munich (NIM) by the German Excellence Initiative, and the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (Grant Agreement No. 771537). N.Y.Y. acknowledges support from the NSF (PHY-1654740), the ARO STIR program, and a Google research award.","abstract":[{"lang":"eng","text":"We analyze a disordered central spin model, where a central spin interacts equally with each spin in a periodic one-dimensional (1D) random-field Heisenberg chain. If the Heisenberg chain is initially in the many-body localized (MBL) phase, we find that the coupling to the central spin suffices to delocalize the chain for a substantial range of coupling strengths. We calculate the phase diagram of the model and identify the phase boundary between the MBL and ergodic phase. Within the localized phase, the central spin significantly enhances the rate of the logarithmic entanglement growth and its saturation value. We attribute the increase in entanglement entropy to a nonextensive enhancement of magnetization fluctuations induced by the central spin. Finally, we demonstrate that correlation functions of the central spin can be utilized to distinguish between MBL and ergodic phases of the 1D chain. Hence, we propose the use of a central spin as a possible experimental probe to identify the MBL phase."}],"date_updated":"2023-09-11T12:55:03Z","status":"public","intvolume":"        98","oa":1,"external_id":{"isi":["000448596500002"],"arxiv":["1806.08316"]},"year":"2018","title":"Detection and characterization of many-body localization in central spin models","issue":"16","isi":1,"day":"15","doi":"10.1103/PhysRevB.98.161122","article_number":"161122","date_published":"2018-10-15T00:00:00Z","article_type":"original","department":[{"_id":"MaSe"}],"oa_version":"Preprint","arxiv":1,"quality_controlled":"1","publication_status":"published","citation":{"chicago":"Hetterich, Daniel, Norman Yao, Maksym Serbyn, Frank Pollmann, and Björn Trauzettel. “Detection and Characterization of Many-Body Localization in Central Spin Models.” <i>Physical Review B</i>. American Physical Society, 2018. <a href=\"https://doi.org/10.1103/PhysRevB.98.161122\">https://doi.org/10.1103/PhysRevB.98.161122</a>.","ama":"Hetterich D, Yao N, Serbyn M, Pollmann F, Trauzettel B. Detection and characterization of many-body localization in central spin models. <i>Physical Review B</i>. 2018;98(16). doi:<a href=\"https://doi.org/10.1103/PhysRevB.98.161122\">10.1103/PhysRevB.98.161122</a>","apa":"Hetterich, D., Yao, N., Serbyn, M., Pollmann, F., &#38; Trauzettel, B. (2018). Detection and characterization of many-body localization in central spin models. <i>Physical Review B</i>. American Physical Society. <a href=\"https://doi.org/10.1103/PhysRevB.98.161122\">https://doi.org/10.1103/PhysRevB.98.161122</a>","ista":"Hetterich D, Yao N, Serbyn M, Pollmann F, Trauzettel B. 2018. Detection and characterization of many-body localization in central spin models. Physical Review B. 98(16), 161122.","ieee":"D. Hetterich, N. Yao, M. Serbyn, F. Pollmann, and B. Trauzettel, “Detection and characterization of many-body localization in central spin models,” <i>Physical Review B</i>, vol. 98, no. 16. American Physical Society, 2018.","short":"D. Hetterich, N. Yao, M. Serbyn, F. Pollmann, B. Trauzettel, Physical Review B 98 (2018).","mla":"Hetterich, Daniel, et al. “Detection and Characterization of Many-Body Localization in Central Spin Models.” <i>Physical Review B</i>, vol. 98, no. 16, 161122, American Physical Society, 2018, doi:<a href=\"https://doi.org/10.1103/PhysRevB.98.161122\">10.1103/PhysRevB.98.161122</a>."}},{"quality_controlled":"1","citation":{"ama":"Kühnen J, Song B, Scarselli D, et al. Destabilizing turbulence in pipe flow. <i>Nature Physics</i>. 2018;14:386-390. doi:<a href=\"https://doi.org/10.1038/s41567-017-0018-3\">10.1038/s41567-017-0018-3</a>","apa":"Kühnen, J., Song, B., Scarselli, D., Budanur, N. B., Riedl, M., Willis, A., … Hof, B. (2018). Destabilizing turbulence in pipe flow. <i>Nature Physics</i>. Nature Publishing Group. <a href=\"https://doi.org/10.1038/s41567-017-0018-3\">https://doi.org/10.1038/s41567-017-0018-3</a>","chicago":"Kühnen, Jakob, Baofang Song, Davide Scarselli, Nazmi B Budanur, Michael Riedl, Ashley Willis, Marc Avila, and Björn Hof. “Destabilizing Turbulence in Pipe Flow.” <i>Nature Physics</i>. Nature Publishing Group, 2018. <a href=\"https://doi.org/10.1038/s41567-017-0018-3\">https://doi.org/10.1038/s41567-017-0018-3</a>.","ieee":"J. Kühnen <i>et al.</i>, “Destabilizing turbulence in pipe flow,” <i>Nature Physics</i>, vol. 14. Nature Publishing Group, pp. 386–390, 2018.","short":"J. Kühnen, B. Song, D. Scarselli, N.B. Budanur, M. Riedl, A. Willis, M. Avila, B. Hof, Nature Physics 14 (2018) 386–390.","mla":"Kühnen, Jakob, et al. “Destabilizing Turbulence in Pipe Flow.” <i>Nature Physics</i>, vol. 14, Nature Publishing Group, 2018, pp. 386–90, doi:<a href=\"https://doi.org/10.1038/s41567-017-0018-3\">10.1038/s41567-017-0018-3</a>.","ista":"Kühnen J, Song B, Scarselli D, Budanur NB, Riedl M, Willis A, Avila M, Hof B. 2018. Destabilizing turbulence in pipe flow. Nature Physics. 14, 386–390."},"publication_status":"published","date_published":"2018-01-08T00:00:00Z","oa_version":"Preprint","department":[{"_id":"BjHo"}],"year":"2018","isi":1,"day":"08","doi":"10.1038/s41567-017-0018-3","title":"Destabilizing turbulence in pipe flow","status":"public","intvolume":"        14","date_updated":"2024-03-25T23:30:20Z","external_id":{"isi":["000429434100020"]},"oa":1,"_id":"461","acknowledgement":"We acknowledge the European Research Council under the European Union’s Seventh Framework Programme (FP/2007-2013)/ERC Grant Agreement 306589, the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement no. 737549) and the Deutsche Forschungsgemeinschaft (Project No. FOR 1182) for financial support. We thank our technician P. Maier for providing highly valuable ideas and greatly supporting us in all technical aspects. We thank M. Schaner for technical drawings, construction and design. We thank M. Schwegel for a Matlab code to post-process experimental data.","abstract":[{"text":"Turbulence is the major cause of friction losses in transport processes and it is responsible for a drastic drag increase in flows over bounding surfaces. While much effort is invested into developing ways to control and reduce turbulence intensities, so far no methods exist to altogether eliminate turbulence if velocities are sufficiently large. We demonstrate for pipe flow that appropriate distortions to the velocity profile lead to a complete collapse of turbulence and subsequently friction losses are reduced by as much as 90%. Counterintuitively, the return to laminar motion is accomplished by initially increasing turbulence intensities or by transiently amplifying wall shear. Since neither the Reynolds number nor the shear stresses decrease (the latter often increase), these measures are not indicative of turbulence collapse. Instead, an amplification mechanism                      measuring the interaction between eddies and the mean shear is found to set a threshold below which turbulence is suppressed beyond recovery.","lang":"eng"}],"publist_id":"7360","ec_funded":1,"publisher":"Nature Publishing Group","project":[{"grant_number":"306589","call_identifier":"FP7","_id":"25152F3A-B435-11E9-9278-68D0E5697425","name":"Decoding the complexity of turbulence at its origin"},{"name":"Eliminating turbulence in oil pipelines","_id":"25104D44-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","grant_number":"737549"}],"main_file_link":[{"url":"https://arxiv.org/abs/1711.06543","open_access":"1"}],"user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","date_created":"2018-12-11T11:46:36Z","page":"386-390","volume":14,"related_material":{"record":[{"status":"public","id":"12726","relation":"dissertation_contains"},{"status":"public","id":"14530","relation":"dissertation_contains"},{"id":"7258","relation":"dissertation_contains","status":"public"}]},"scopus_import":"1","article_processing_charge":"No","publication":"Nature Physics","month":"01","author":[{"orcid":"0000-0003-4312-0179","id":"3A47AE32-F248-11E8-B48F-1D18A9856A87","last_name":"Kühnen","full_name":"Kühnen, Jakob","first_name":"Jakob"},{"last_name":"Song","first_name":"Baofang","full_name":"Song, Baofang"},{"first_name":"Davide","full_name":"Scarselli, Davide","last_name":"Scarselli","id":"40315C30-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-5227-4271"},{"last_name":"Budanur","full_name":"Budanur, Nazmi B","first_name":"Nazmi B","orcid":"0000-0003-0423-5010","id":"3EA1010E-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Riedl","full_name":"Riedl, Michael","first_name":"Michael","id":"3BE60946-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-4844-6311"},{"first_name":"Ashley","full_name":"Willis, Ashley","last_name":"Willis"},{"last_name":"Avila","full_name":"Avila, Marc","first_name":"Marc"},{"id":"3A374330-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-2057-2754","last_name":"Hof","first_name":"Björn","full_name":"Hof, Björn"}],"language":[{"iso":"eng"}],"type":"journal_article"},{"publisher":"Wiley-Blackwell","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","publist_id":"7359","abstract":[{"lang":"eng","text":"AtNHX5 and AtNHX6 are endosomal Na+,K+/H+ antiporters that are critical for growth and development in Arabidopsis, but the mechanism behind their action remains unknown. Here, we report that AtNHX5 and AtNHX6, functioning as H+ leak, control auxin homeostasis and auxin-mediated development. We found that nhx5 nhx6 exhibited growth variations of auxin-related defects. We further showed that nhx5 nhx6 was affected in auxin homeostasis. Genetic analysis showed that AtNHX5 and AtNHX6 were required for the function of the ER-localized auxin transporter PIN5. Although AtNHX5 and AtNHX6 were co-localized with PIN5 at ER, they did not interact directly. Instead, the conserved acidic residues in AtNHX5 and AtNHX6, which are essential for exchange activity, were required for PIN5 function. AtNHX5 and AtNHX6 regulated the pH in ER. Overall, AtNHX5 and AtNHX6 may regulate auxin transport across the ER via the pH gradient created by their transport activity. H+-leak pathway provides a fine-tuning mechanism that controls cellular auxin fluxes. "}],"acknowledgement":"This work was supported by the National Natural Science Foundation of China (31571464, 31371438 and 31070222 to Q.S.Q.), the National Basic Research Program of China (973 project, 2013CB429904 to Q.S.Q.), the Research Fund for the Doctoral Program of Higher Education of China (20130211110001 to Q.S.Q.), the Ministry of Education, Youth and Sports of the Czech Republic (the National Program for Sustainability I, LO1204), and The Czech Science Foundation GAČR (GA13–40637S) to JF. We thank Dr. Tom J. Guilfoyle for DR5::GUS line and Dr. Jia Li for pBIB‐RFP vector and DR5::GFP line. We thank Liping Guan and Yang Zhao for their help with the confocal microscope assay. ","_id":"462","pmid":1,"type":"journal_article","month":"05","author":[{"full_name":"Fan, Ligang","first_name":"Ligang","last_name":"Fan"},{"first_name":"Lei","full_name":"Zhao, Lei","last_name":"Zhao"},{"first_name":"Wei","full_name":"Hu, Wei","last_name":"Hu"},{"last_name":"Li","first_name":"Weina","full_name":"Li, Weina"},{"last_name":"Novák","full_name":"Novák, Ondřej","first_name":"Ondřej"},{"last_name":"Strnad","first_name":"Miroslav","full_name":"Strnad, Miroslav"},{"id":"4542EF9A-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-1998-6741","first_name":"Sibu","full_name":"Simon, Sibu","last_name":"Simon"},{"last_name":"Friml","full_name":"Friml, Jirí","first_name":"Jirí","id":"4159519E-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8302-7596"},{"first_name":"Jinbo","full_name":"Shen, Jinbo","last_name":"Shen"},{"full_name":"Jiang, Liwen","first_name":"Liwen","last_name":"Jiang"},{"last_name":"Qiu","full_name":"Qiu, Quan","first_name":"Quan"}],"language":[{"iso":"eng"}],"scopus_import":"1","publication":"Plant, Cell and Environment","article_processing_charge":"No","file_date_updated":"2020-07-14T12:46:32Z","volume":41,"ddc":["580"],"date_created":"2018-12-11T11:46:36Z","page":"850 - 864","file":[{"creator":"dernst","content_type":"application/pdf","file_id":"7042","date_created":"2019-11-18T16:22:22Z","file_name":"2018_PlantCellEnv_Fan.pdf","file_size":1937976,"checksum":"6a20f843565f962cb20281cdf5e40914","access_level":"open_access","relation":"main_file","date_updated":"2020-07-14T12:46:32Z"}],"oa_version":"Submitted Version","department":[{"_id":"JiFr"}],"article_type":"original","date_published":"2018-05-01T00:00:00Z","citation":{"ista":"Fan L, Zhao L, Hu W, Li W, Novák O, Strnad M, Simon S, Friml J, Shen J, Jiang L, Qiu Q. 2018. NHX antiporters regulate the pH of endoplasmic reticulum and auxin-mediated development. Plant, Cell and Environment. 41, 850–864.","short":"L. Fan, L. Zhao, W. Hu, W. Li, O. Novák, M. Strnad, S. Simon, J. Friml, J. Shen, L. Jiang, Q. Qiu, Plant, Cell and Environment 41 (2018) 850–864.","mla":"Fan, Ligang, et al. “NHX Antiporters Regulate the PH of Endoplasmic Reticulum and Auxin-Mediated Development.” <i>Plant, Cell and Environment</i>, vol. 41, Wiley-Blackwell, 2018, pp. 850–64, doi:<a href=\"https://doi.org/10.1111/pce.13153\">10.1111/pce.13153</a>.","ieee":"L. Fan <i>et al.</i>, “NHX antiporters regulate the pH of endoplasmic reticulum and auxin-mediated development,” <i>Plant, Cell and Environment</i>, vol. 41. Wiley-Blackwell, pp. 850–864, 2018.","chicago":"Fan, Ligang, Lei Zhao, Wei Hu, Weina Li, Ondřej Novák, Miroslav Strnad, Sibu Simon, et al. “NHX Antiporters Regulate the PH of Endoplasmic Reticulum and Auxin-Mediated Development.” <i>Plant, Cell and Environment</i>. Wiley-Blackwell, 2018. <a href=\"https://doi.org/10.1111/pce.13153\">https://doi.org/10.1111/pce.13153</a>.","ama":"Fan L, Zhao L, Hu W, et al. NHX antiporters regulate the pH of endoplasmic reticulum and auxin-mediated development. <i>Plant, Cell and Environment</i>. 2018;41:850-864. doi:<a href=\"https://doi.org/10.1111/pce.13153\">10.1111/pce.13153</a>","apa":"Fan, L., Zhao, L., Hu, W., Li, W., Novák, O., Strnad, M., … Qiu, Q. (2018). NHX antiporters regulate the pH of endoplasmic reticulum and auxin-mediated development. <i>Plant, Cell and Environment</i>. Wiley-Blackwell. <a href=\"https://doi.org/10.1111/pce.13153\">https://doi.org/10.1111/pce.13153</a>"},"publication_status":"published","quality_controlled":"1","external_id":{"isi":["000426870500012"],"pmid":["29360148"]},"license":"https://creativecommons.org/licenses/by-nc/4.0/","oa":1,"intvolume":"        41","status":"public","date_updated":"2023-09-13T09:03:18Z","day":"01","tmp":{"short":"CC BY-NC (4.0)","name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode","image":"/images/cc_by_nc.png"},"doi":"10.1111/pce.13153","isi":1,"title":"NHX antiporters regulate the pH of endoplasmic reticulum and auxin-mediated development","has_accepted_license":"1","year":"2018"},{"date_updated":"2024-03-25T23:30:22Z","intvolume":"        87","status":"public","external_id":{"isi":["000453657800006"]},"year":"2018","title":"Transporters and mechanisms of hormone transport in arabidopsis","doi":"10.1016/bs.abr.2018.09.007","day":"01","isi":1,"date_published":"2018-01-01T00:00:00Z","department":[{"_id":"EvBe"}],"oa_version":"None","quality_controlled":"1","publication_status":"published","citation":{"apa":"Abualia, R., Benková, E., &#38; Lacombe, B. (2018). Transporters and mechanisms of hormone transport in arabidopsis. <i>Advances in Botanical Research</i>. Elsevier. <a href=\"https://doi.org/10.1016/bs.abr.2018.09.007\">https://doi.org/10.1016/bs.abr.2018.09.007</a>","ama":"Abualia R, Benková E, Lacombe B. Transporters and mechanisms of hormone transport in arabidopsis. <i>Advances in Botanical Research</i>. 2018;87:115-138. doi:<a href=\"https://doi.org/10.1016/bs.abr.2018.09.007\">10.1016/bs.abr.2018.09.007</a>","chicago":"Abualia, Rashed, Eva Benková, and Benoît Lacombe. “Transporters and Mechanisms of Hormone Transport in Arabidopsis.” <i>Advances in Botanical Research</i>. Elsevier, 2018. <a href=\"https://doi.org/10.1016/bs.abr.2018.09.007\">https://doi.org/10.1016/bs.abr.2018.09.007</a>.","mla":"Abualia, Rashed, et al. “Transporters and Mechanisms of Hormone Transport in Arabidopsis.” <i>Advances in Botanical Research</i>, vol. 87, Elsevier, 2018, pp. 115–38, doi:<a href=\"https://doi.org/10.1016/bs.abr.2018.09.007\">10.1016/bs.abr.2018.09.007</a>.","short":"R. Abualia, E. Benková, B. Lacombe, Advances in Botanical Research 87 (2018) 115–138.","ieee":"R. Abualia, E. Benková, and B. Lacombe, “Transporters and mechanisms of hormone transport in arabidopsis,” <i>Advances in Botanical Research</i>, vol. 87. Elsevier, pp. 115–138, 2018.","ista":"Abualia R, Benková E, Lacombe B. 2018. Transporters and mechanisms of hormone transport in arabidopsis. Advances in Botanical Research. 87, 115–138."},"publication":"Advances in Botanical Research","article_processing_charge":"No","scopus_import":"1","type":"journal_article","month":"01","language":[{"iso":"eng"}],"author":[{"orcid":"0000-0002-9357-9415","id":"4827E134-F248-11E8-B48F-1D18A9856A87","full_name":"Abualia, Rashed","first_name":"Rashed","last_name":"Abualia"},{"orcid":"0000-0002-8510-9739","id":"38F4F166-F248-11E8-B48F-1D18A9856A87","last_name":"Benková","full_name":"Benková, Eva","first_name":"Eva"},{"first_name":"Benoît","full_name":"Lacombe, Benoît","last_name":"Lacombe"}],"page":"115 - 138","date_created":"2018-12-11T11:44:20Z","related_material":{"record":[{"id":"10303","relation":"dissertation_contains","status":"public"}]},"volume":87,"publist_id":"8007","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","publisher":"Elsevier","_id":"47","abstract":[{"lang":"eng","text":"Plant hormones as signalling molecules play an essential role in the control of plant growth and development. Typically, sites of hormonal action are usually distant from the site of biosynthesis thus relying on efficient transport mechanisms. Over the last decades, molecular identification of proteins and protein complexes involved in hormonal transport has started. Advanced screens for genes involved in hormonal transport in combination with transport assays using heterologous systems such as yeast, insect, or tobacco BY2 cells or Xenopus oocytes provided important insights into mechanisms underlying distribution of hormones in plant body and led to identification of principal transporters for each hormone. This review gives a short overview of the mechanisms of hormonal transport and transporters identified in Arabidopsis thaliana."}]},{"date_created":"2018-12-11T11:44:21Z","page":"104","ddc":["573"],"file_date_updated":"2021-02-11T23:30:22Z","article_processing_charge":"No","language":[{"iso":"eng"}],"author":[{"id":"4B60654C-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-1807-1929","full_name":"Gridchyn, Igor","first_name":"Igor","last_name":"Gridchyn"}],"month":"08","type":"dissertation","_id":"48","alternative_title":["ISTA Thesis"],"abstract":[{"text":"The hippocampus is a key brain region for spatial memory and navigation and is needed at all stages of memory, including encoding, consolidation, and recall. Hippocampal place cells selectively discharge at specific locations of the environment to form a cognitive map of the space. During the rest period and sleep following spatial navigation and/or learning, the waking activity of the place cells is reactivated within high synchrony events. This reactivation is thought to be important for memory consolidation and stabilization of the spatial representations. The aim of my thesis was to directly test whether the reactivation content encoded in firing patterns of place cells is important for consolidation of spatial memories. In particular, I aimed to test whether, in cases when multiple spatial memory traces are acquired during learning, the specific disruption of the reactivation of a subset of these memories leads to the selective disruption of the corresponding memory traces or through memory interference the other learned memories are disrupted as well. In this thesis, using a modified cheeseboard paradigm and a closed-loop recording setup with feedback optogenetic stimulation, I examined how the disruption of the reactivation of specific spiking patterns affects consolidation of the corresponding memory traces. To obtain multiple distinctive memories, animals had to perform a spatial task in two distinct cheeseboard environments and the reactivation of spiking patterns associated with one of the environments (target) was disrupted after learning during four hours rest period using a real-time decoding method. This real-time decoding method was capable of selectively affecting the firing rates and cofiring correlations of the target environment-encoding cells. The selective disruption led to behavioural impairment in the memory tests after the rest periods in the target environment but not in the other undisrupted control environment. In addition, the map of the target environment was less stable in the impaired memory tests compared to the learning session before than the map of the control environment. However, when the animal relearned the task, the same map recurred in the target environment that was present during learning before the disruption. Altogether my work demonstrated that the reactivation content is important: assembly-related disruption of reactivation can lead to a selective memory impairment and deficiency in map stability. These findings indeed suggest that reactivated assembly patterns reflect processes associated with the consolidation of memory traces. ","lang":"eng"}],"publist_id":"8006","publisher":"Institute of Science and Technology Austria","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","year":"2018","degree_awarded":"PhD","day":"27","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"doi":"10.15479/AT:ISTA:th_1042","title":"Reactivation content is important for consolidation of spatial memory","publication_identifier":{"issn":["2663-337X"]},"has_accepted_license":"1","status":"public","pubrep_id":"1042","date_updated":"2023-09-07T12:42:44Z","license":"https://creativecommons.org/licenses/by/4.0/","oa":1,"supervisor":[{"id":"3FA14672-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-5193-4036","last_name":"Csicsvari","first_name":"Jozsef L","full_name":"Csicsvari, Jozsef L"}],"publication_status":"published","citation":{"ista":"Gridchyn I. 2018. Reactivation content is important for consolidation of spatial memory. Institute of Science and Technology Austria.","mla":"Gridchyn, Igor. <i>Reactivation Content Is Important for Consolidation of Spatial Memory</i>. Institute of Science and Technology Austria, 2018, doi:<a href=\"https://doi.org/10.15479/AT:ISTA:th_1042\">10.15479/AT:ISTA:th_1042</a>.","short":"I. Gridchyn, Reactivation Content Is Important for Consolidation of Spatial Memory, Institute of Science and Technology Austria, 2018.","ieee":"I. Gridchyn, “Reactivation content is important for consolidation of spatial memory,” Institute of Science and Technology Austria, 2018.","chicago":"Gridchyn, Igor. “Reactivation Content Is Important for Consolidation of Spatial Memory.” Institute of Science and Technology Austria, 2018. <a href=\"https://doi.org/10.15479/AT:ISTA:th_1042\">https://doi.org/10.15479/AT:ISTA:th_1042</a>.","apa":"Gridchyn, I. (2018). <i>Reactivation content is important for consolidation of spatial memory</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT:ISTA:th_1042\">https://doi.org/10.15479/AT:ISTA:th_1042</a>","ama":"Gridchyn I. Reactivation content is important for consolidation of spatial memory. 2018. doi:<a href=\"https://doi.org/10.15479/AT:ISTA:th_1042\">10.15479/AT:ISTA:th_1042</a>"},"date_published":"2018-08-27T00:00:00Z","file":[{"date_updated":"2021-02-11T23:30:22Z","file_size":7666687,"checksum":"7db4415e435590fa33542c7b0a0321d7","relation":"source_file","access_level":"closed","file_name":"2018_Thesis_Gridchyn_source.docx","embargo_to":"open_access","date_created":"2019-04-08T13:36:01Z","content_type":"application/vnd.openxmlformats-officedocument.wordprocessingml.document","file_id":"6236","creator":"dernst"},{"creator":"dernst","date_created":"2019-04-08T13:36:01Z","file_id":"6237","content_type":"application/pdf","relation":"main_file","access_level":"open_access","checksum":"f96f3fe8979f7b1e6db6acaca962b10c","file_size":6034153,"embargo":"2019-08-29","file_name":"2018_Thesis_Gridchyn.pdf","date_updated":"2021-02-11T11:17:18Z"}],"oa_version":"Published Version","department":[{"_id":"JoCs"}]},{"year":"2018","degree_awarded":"PhD","day":"30","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"doi":"10.15479/AT:ISTA:th_1033","title":"Ge hut wires - from growth to hole spin resonance","publication_identifier":{"issn":["2663-337X"]},"has_accepted_license":"1","status":"public","pubrep_id":"1033","date_updated":"2023-09-07T12:27:43Z","oa":1,"supervisor":[{"last_name":"Katsaros","first_name":"Georgios","full_name":"Katsaros, Georgios","orcid":"0000-0001-8342-202X","id":"38DB5788-F248-11E8-B48F-1D18A9856A87"}],"citation":{"chicago":"Watzinger, Hannes. “Ge Hut Wires - from Growth to Hole Spin Resonance.” Institute of Science and Technology Austria, 2018. <a href=\"https://doi.org/10.15479/AT:ISTA:th_1033\">https://doi.org/10.15479/AT:ISTA:th_1033</a>.","ama":"Watzinger H. Ge hut wires - from growth to hole spin resonance. 2018. doi:<a href=\"https://doi.org/10.15479/AT:ISTA:th_1033\">10.15479/AT:ISTA:th_1033</a>","apa":"Watzinger, H. (2018). <i>Ge hut wires - from growth to hole spin resonance</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT:ISTA:th_1033\">https://doi.org/10.15479/AT:ISTA:th_1033</a>","ista":"Watzinger H. 2018. Ge hut wires - from growth to hole spin resonance. Institute of Science and Technology Austria.","short":"H. Watzinger, Ge Hut Wires - from Growth to Hole Spin Resonance, Institute of Science and Technology Austria, 2018.","mla":"Watzinger, Hannes. <i>Ge Hut Wires - from Growth to Hole Spin Resonance</i>. Institute of Science and Technology Austria, 2018, doi:<a href=\"https://doi.org/10.15479/AT:ISTA:th_1033\">10.15479/AT:ISTA:th_1033</a>.","ieee":"H. Watzinger, “Ge hut wires - from growth to hole spin resonance,” Institute of Science and Technology Austria, 2018."},"publication_status":"published","date_published":"2018-07-30T00:00:00Z","file":[{"file_name":"2018_Thesis_Watzinger.pdf","access_level":"open_access","relation":"main_file","checksum":"b653b5216251f938ddbeafd1de88667c","file_size":85539748,"date_updated":"2020-07-14T12:46:35Z","creator":"dernst","file_id":"6249","content_type":"application/pdf","date_created":"2019-04-09T07:13:28Z"},{"content_type":"application/zip","file_id":"6250","date_created":"2019-04-09T07:13:27Z","creator":"dernst","date_updated":"2020-07-14T12:46:35Z","file_name":"2018_Thesis_Watzinger_source.zip","checksum":"39bcf8de7ac5b1bb516b11ce2f966785","file_size":21830697,"relation":"source_file","access_level":"closed"}],"oa_version":"Published Version","department":[{"_id":"GeKa"}],"date_created":"2018-12-11T11:44:21Z","page":"77","ddc":["530"],"file_date_updated":"2020-07-14T12:46:35Z","article_processing_charge":"No","author":[{"first_name":"Hannes","full_name":"Watzinger, Hannes","last_name":"Watzinger","id":"35DF8E50-F248-11E8-B48F-1D18A9856A87"}],"language":[{"iso":"eng"}],"month":"07","type":"dissertation","_id":"49","alternative_title":["ISTA Thesis"],"abstract":[{"text":"Nowadays, quantum computation is receiving more and more attention as an alternative to the classical way of computing. For realizing a quantum computer, different devices are investigated as potential quantum bits. In this thesis, the focus is on Ge hut wires, which turned out to be promising candidates for implementing hole spin quantum bits. The advantages of Ge as a material system are the low hyperfine interaction for holes and the strong spin orbit coupling, as well as the compatibility with the highly developed CMOS processes in industry. In addition, Ge can also be isotopically purified which is expected to boost the spin coherence times. The strong spin orbit interaction for holes in Ge on the one hand enables the full electrical control of the quantum bit and on the other hand should allow short spin manipulation times. Starting with a bare Si wafer, this work covers the entire process reaching from growth over the fabrication and characterization of hut wire devices up to the demonstration of hole spin resonance. From experiments with single quantum dots, a large g-factor anisotropy between the in-plane and the out-of-plane direction was found. A comparison to a theoretical model unveiled the heavy-hole character of the lowest energy states. The second part of the thesis addresses double quantum dot devices, which were realized by adding two gate electrodes to a hut wire. In such devices, Pauli spin blockade was observed, which can serve as a read-out mechanism for spin quantum bits. Applying oscillating electric fields in spin blockade allowed the demonstration of continuous spin rotations and the extraction of a lower bound for the spin dephasing time. Despite the strong spin orbit coupling in Ge, the obtained value for the dephasing time is comparable to what has been recently reported for holes in Si. All in all, the presented results point out the high potential of Ge hut wires as a platform for long-lived, fast and fully electrically tunable hole spin quantum bits.","lang":"eng"}],"publist_id":"8005","publisher":"Institute of Science and Technology Austria","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1"},{"type":"dissertation","language":[{"iso":"eng"}],"author":[{"orcid":"0000-0001-5199-9940","id":"31C42484-F248-11E8-B48F-1D18A9856A87","first_name":"Daniel","full_name":"Capek, Daniel","last_name":"Capek"}],"month":"06","article_processing_charge":"No","related_material":{"record":[{"status":"public","relation":"part_of_dissertation","id":"1100"},{"id":"661","relation":"part_of_dissertation","status":"public"},{"id":"676","relation":"part_of_dissertation","status":"public"}]},"file_date_updated":"2021-02-11T23:30:21Z","ddc":["570","591","596"],"page":"95","date_created":"2018-12-11T11:44:21Z","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","publisher":"Institute of Science and Technology Austria","publist_id":"8004","abstract":[{"text":"The Wnt/planar cell polarity (Wnt/PCP) pathway determines planar polarity of epithelial cells in both vertebrates and invertebrates. The role that Wnt/PCP signaling plays in mesenchymal contexts, however, is only poorly understood. While previous studies have demonstrated the capacity of Wnt/PCP signaling to polarize and guide directed migration of mesenchymal cells, it remains unclear whether endogenous Wnt/PCP signaling performs these functions instructively, as it does in epithelial cells. Here we developed a light-switchable version of the Wnt/PCP receptor Frizzled 7 (Fz7) to unambiguously distinguish between an instructive and a permissive role of Wnt/PCP signaling for the directional collective migration of mesendoderm progenitor cells during zebrafish gastrulation. We show that prechordal plate (ppl) cell migration is defective in maternal-zygotic fz7a and fz7b (MZ fz7a,b) double mutant embryos, and that Fz7 functions cell-autonomously in this process by promoting ppl cell protrusion formation and directed migration. We further show that local activation of Fz7 can direct ppl cell migration both in vitro and in vivo. Surprisingly, however, uniform Fz7 activation is sufficient to fully rescue the ppl cell migration defect in MZ fz7a,b mutant embryos, indicating that Wnt/PCP signaling functions permissively rather than instructively in directed mesendoderm cell migration during zebrafish gastrulation.","lang":"eng"}],"alternative_title":["ISTA Thesis"],"_id":"50","supervisor":[{"orcid":"0000-0002-0912-4566","id":"39427864-F248-11E8-B48F-1D18A9856A87","full_name":"Heisenberg, Carl-Philipp J","first_name":"Carl-Philipp J","last_name":"Heisenberg"}],"oa":1,"date_updated":"2023-09-07T12:48:16Z","pubrep_id":"1031","status":"public","title":"Optogenetic Frizzled 7 reveals a permissive function of Wnt/PCP signaling in directed mesenchymal cell migration","publication_identifier":{"issn":["2663-337X"]},"has_accepted_license":"1","doi":"10.15479/AT:ISTA:TH_1031","day":"22","degree_awarded":"PhD","year":"2018","department":[{"_id":"CaHe"}],"oa_version":"Published Version","file":[{"creator":"dernst","date_created":"2019-04-08T13:42:26Z","content_type":"application/pdf","file_id":"6238","file_size":31576521,"checksum":"d3eca3dcacb67bffdde6e6609c31cdd0","relation":"main_file","access_level":"open_access","file_name":"2018_Thesis_Capek.pdf","embargo":"2019-06-25","date_updated":"2021-02-11T11:17:17Z"},{"creator":"dernst","date_created":"2019-04-08T13:42:27Z","content_type":"application/vnd.openxmlformats-officedocument.wordprocessingml.document","file_id":"6239","file_size":38992956,"checksum":"876deb14067e638aba65d209668bd821","access_level":"closed","relation":"source_file","file_name":"2018_Thesis_Capek_source.docx","embargo_to":"open_access","date_updated":"2021-02-11T23:30:21Z"}],"date_published":"2018-06-22T00:00:00Z","publication_status":"published","citation":{"ista":"Capek D. 2018. Optogenetic Frizzled 7 reveals a permissive function of Wnt/PCP signaling in directed mesenchymal cell migration. Institute of Science and Technology Austria.","short":"D. Capek, Optogenetic Frizzled 7 Reveals a Permissive Function of Wnt/PCP Signaling in Directed Mesenchymal Cell Migration, Institute of Science and Technology Austria, 2018.","mla":"Capek, Daniel. <i>Optogenetic Frizzled 7 Reveals a Permissive Function of Wnt/PCP Signaling in Directed Mesenchymal Cell Migration</i>. Institute of Science and Technology Austria, 2018, doi:<a href=\"https://doi.org/10.15479/AT:ISTA:TH_1031\">10.15479/AT:ISTA:TH_1031</a>.","ieee":"D. Capek, “Optogenetic Frizzled 7 reveals a permissive function of Wnt/PCP signaling in directed mesenchymal cell migration,” Institute of Science and Technology Austria, 2018.","chicago":"Capek, Daniel. “Optogenetic Frizzled 7 Reveals a Permissive Function of Wnt/PCP Signaling in Directed Mesenchymal Cell Migration.” Institute of Science and Technology Austria, 2018. <a href=\"https://doi.org/10.15479/AT:ISTA:TH_1031\">https://doi.org/10.15479/AT:ISTA:TH_1031</a>.","apa":"Capek, D. (2018). <i>Optogenetic Frizzled 7 reveals a permissive function of Wnt/PCP signaling in directed mesenchymal cell migration</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT:ISTA:TH_1031\">https://doi.org/10.15479/AT:ISTA:TH_1031</a>","ama":"Capek D. Optogenetic Frizzled 7 reveals a permissive function of Wnt/PCP signaling in directed mesenchymal cell migration. 2018. doi:<a href=\"https://doi.org/10.15479/AT:ISTA:TH_1031\">10.15479/AT:ISTA:TH_1031</a>"}},{"volume":268,"date_created":"2018-12-11T11:46:50Z","page":"40 - 52","author":[{"last_name":"Tomasek","first_name":"Kathrin","full_name":"Tomasek, Kathrin","orcid":"0000-0003-3768-877X","id":"3AEC8556-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Bergmiller, Tobias","first_name":"Tobias","last_name":"Bergmiller","orcid":"0000-0001-5396-4346","id":"2C471CFA-F248-11E8-B48F-1D18A9856A87"},{"orcid":"0000-0001-6220-2052","id":"47F8433E-F248-11E8-B48F-1D18A9856A87","first_name":"Calin C","full_name":"Guet, Calin C","last_name":"Guet"}],"month":"02","language":[{"iso":"eng"}],"type":"journal_article","scopus_import":"1","article_processing_charge":"No","publication":"Journal of Biotechnology","abstract":[{"lang":"eng","text":"Buffers are essential for diluting bacterial cultures for flow cytometry analysis in order to study bacterial physiology and gene expression parameters based on fluorescence signals. Using a variety of constitutively expressed fluorescent proteins in Escherichia coli K-12 strain MG1655, we found strong artifactual changes in fluorescence levels after dilution into the commonly used flow cytometry buffer phosphate-buffered saline (PBS) and two other buffer solutions, Tris-HCl and M9 salts. These changes appeared very rapidly after dilution, and were linked to increased membrane permeability and loss in cell viability. We observed buffer-related effects in several different E. coli strains, K-12, C and W, but not E. coli B, which can be partially explained by differences in lipopolysaccharide (LPS) and outer membrane composition. Supplementing the buffers with divalent cations responsible for outer membrane stability, Mg2+ and Ca2+, preserved fluorescence signals, membrane integrity and viability of E. coli. Thus, stabilizing the bacterial outer membrane is essential for precise and unbiased measurements of fluorescence parameters using flow cytometry."}],"_id":"503","acknowledgement":"We thank R Chait and M Lagator for sharing Bacillus subtilis CR_Y1 and pZS*_2R-cIPtet-Venus-Prm, respectively. We are grateful to T Pilizota and all members of the Guet lab for critically reading the manuscript. We also thank the Bioimaging facility at IST Austria for assistance using the FACSAria III system.\r\n\r\n","publisher":"Elsevier","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","publist_id":"7317","acknowledged_ssus":[{"_id":"Bio"}],"isi":1,"doi":"10.1016/j.jbiotec.2018.01.008","day":"20","title":"Lack of cations in flow cytometry buffers affect fluorescence signals by reducing membrane stability and viability of Escherichia coli strains","year":"2018","external_id":{"isi":["000425715100006"]},"status":"public","intvolume":"       268","date_updated":"2023-09-13T08:24:51Z","citation":{"ieee":"K. Tomasek, T. Bergmiller, and C. C. Guet, “Lack of cations in flow cytometry buffers affect fluorescence signals by reducing membrane stability and viability of Escherichia coli strains,” <i>Journal of Biotechnology</i>, vol. 268. Elsevier, pp. 40–52, 2018.","mla":"Tomasek, Kathrin, et al. “Lack of Cations in Flow Cytometry Buffers Affect Fluorescence Signals by Reducing Membrane Stability and Viability of Escherichia Coli Strains.” <i>Journal of Biotechnology</i>, vol. 268, Elsevier, 2018, pp. 40–52, doi:<a href=\"https://doi.org/10.1016/j.jbiotec.2018.01.008\">10.1016/j.jbiotec.2018.01.008</a>.","short":"K. Tomasek, T. Bergmiller, C.C. Guet, Journal of Biotechnology 268 (2018) 40–52.","ista":"Tomasek K, Bergmiller T, Guet CC. 2018. Lack of cations in flow cytometry buffers affect fluorescence signals by reducing membrane stability and viability of Escherichia coli strains. Journal of Biotechnology. 268, 40–52.","apa":"Tomasek, K., Bergmiller, T., &#38; Guet, C. C. (2018). Lack of cations in flow cytometry buffers affect fluorescence signals by reducing membrane stability and viability of Escherichia coli strains. <i>Journal of Biotechnology</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.jbiotec.2018.01.008\">https://doi.org/10.1016/j.jbiotec.2018.01.008</a>","ama":"Tomasek K, Bergmiller T, Guet CC. Lack of cations in flow cytometry buffers affect fluorescence signals by reducing membrane stability and viability of Escherichia coli strains. <i>Journal of Biotechnology</i>. 2018;268:40-52. doi:<a href=\"https://doi.org/10.1016/j.jbiotec.2018.01.008\">10.1016/j.jbiotec.2018.01.008</a>","chicago":"Tomasek, Kathrin, Tobias Bergmiller, and Calin C Guet. “Lack of Cations in Flow Cytometry Buffers Affect Fluorescence Signals by Reducing Membrane Stability and Viability of Escherichia Coli Strains.” <i>Journal of Biotechnology</i>. Elsevier, 2018. <a href=\"https://doi.org/10.1016/j.jbiotec.2018.01.008\">https://doi.org/10.1016/j.jbiotec.2018.01.008</a>."},"publication_status":"published","quality_controlled":"1","oa_version":"None","department":[{"_id":"CaGu"}],"date_published":"2018-02-20T00:00:00Z"},{"abstract":[{"text":"Asymmetries have long been known about in the central nervous system. From gross anatomical differences, such as the presence of the parapineal organ in only one hemisphere of the developing zebrafish, to more subtle differences in activity between both hemispheres, as seen in freely roaming animals or human participants under PET and fMRI imaging analysis. The presence of asymmetries has been demonstrated to have huge behavioural implications, with their disruption often leading to the generation of neurological disorders, memory problems, changes in personality, and in an organism's health and well-being. For my Ph.D. work I aimed to tackle two important avenues of research. The first being the process of input-side dependency in the hippocampus, with the goal of finding a key gene responsible for its development (Gene X). The second project was to do with experience-induced laterality formation in the hippocampus. Specifically, how laterality in the synapse density of the CA1 stratum radiatum (s.r.) could be induced purely through environmental enrichment. Through unilateral tracer injections into the CA3, I was able to selectively measure the properties of synapses within the CA1 and investigate how they differed based upon which hemisphere the presynaptic neurone originated. Having found the existence of a previously unreported reversed (left-isomerism) i.v. mutant, through morpholocal examination of labelled terminals in the CA1 s.r., I aimed to elucidate a key gene responsible for the process of left or right determination of inputs to the CA1 s.r.. This work relates to the previous finding of input-side dependent asymmetry in the wild-type rodent, where the origin of the projecting neurone to the CA1 will determine the morphology of a synapse, to a greater degree than the hemisphere in which the projection terminates. Using left- and right-isomerism i.v. mice, in combination with whole genome sequence analysis, I highlight Ena/VASP-like (Evl) as a potential target for Gene X. In relation to this topic, I also highlight my work in the recently published paper of how knockout of PirB can lead to a lack of input-side dependency in the murine hippocampus. For the second question, I show that the environmental enrichment paradigm will lead to an asymmetry in the synapse densities in the hippocampus of mice. I also highlight that the nature of the enrichment is of less consequence than the process of enrichment itself. I demonstrate that the CA3 region will dramatically alter its projection targets, in relation to environmental stimulation, with the asymmetry in synaptic density, caused by enrichment, relying heavily on commissural fibres. I also highlight the vital importance of input-side dependent asymmetry, as a necessary component of experience-dependent laterality formation in the CA1 s.r.. However, my results suggest that it isn't the only cause, as there appears to be a CA1 dependent mechanism also at play. Upon further investigation, I highlight the significant, and highly important, finding that the changes seen in the CA1 s.r. were predominantly caused through projections from the left-CA3, with the right-CA3 having less involvement in this mechanism.","lang":"eng"}],"_id":"51","alternative_title":["ISTA Thesis"],"publisher":"Institute of Science and Technology Austria","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","publist_id":"8003","ddc":["571","576"],"related_material":{"record":[{"status":"public","relation":"part_of_dissertation","id":"682"}]},"file_date_updated":"2021-02-11T23:30:13Z","date_created":"2018-12-11T11:44:22Z","page":"186","month":"06","language":[{"iso":"eng"}],"author":[{"id":"44B7CA5A-F248-11E8-B48F-1D18A9856A87","first_name":"Matthew J","full_name":"Case, Matthew J","last_name":"Case"}],"type":"dissertation","article_processing_charge":"No","publication_status":"published","citation":{"chicago":"Case, Matthew J. “From the Left to the Right: A Tale of Asymmetries, Environments, and Hippocampal Development.” Institute of Science and Technology Austria, 2018. <a href=\"https://doi.org/10.15479/AT:ISTA:th_1032\">https://doi.org/10.15479/AT:ISTA:th_1032</a>.","apa":"Case, M. J. (2018). <i>From the left to the right: A tale of asymmetries, environments, and hippocampal development</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT:ISTA:th_1032\">https://doi.org/10.15479/AT:ISTA:th_1032</a>","ama":"Case MJ. From the left to the right: A tale of asymmetries, environments, and hippocampal development. 2018. doi:<a href=\"https://doi.org/10.15479/AT:ISTA:th_1032\">10.15479/AT:ISTA:th_1032</a>","ista":"Case MJ. 2018. From the left to the right: A tale of asymmetries, environments, and hippocampal development. Institute of Science and Technology Austria.","ieee":"M. J. Case, “From the left to the right: A tale of asymmetries, environments, and hippocampal development,” Institute of Science and Technology Austria, 2018.","short":"M.J. Case, From the Left to the Right: A Tale of Asymmetries, Environments, and Hippocampal Development, Institute of Science and Technology Austria, 2018.","mla":"Case, Matthew J. <i>From the Left to the Right: A Tale of Asymmetries, Environments, and Hippocampal Development</i>. Institute of Science and Technology Austria, 2018, doi:<a href=\"https://doi.org/10.15479/AT:ISTA:th_1032\">10.15479/AT:ISTA:th_1032</a>."},"oa_version":"Published Version","file":[{"embargo_to":"open_access","file_name":"2018_Thesis_Case_Source.doc","relation":"source_file","access_level":"closed","file_size":141270528,"checksum":"dcc7b55619d8509dd62b8e99d6cdee44","date_updated":"2021-02-11T23:30:13Z","creator":"dernst","file_id":"6251","content_type":"application/msword","date_created":"2019-04-09T07:16:26Z"},{"date_created":"2019-04-09T07:16:23Z","file_id":"6252","content_type":"application/pdf","creator":"dernst","date_updated":"2021-02-11T11:17:14Z","relation":"main_file","access_level":"open_access","file_size":15193621,"checksum":"f69fdd5c8709c4e618aa8c1a1221153d","embargo":"2019-07-05","file_name":"2018_Thesis_Case.pdf"}],"department":[{"_id":"RySh"}],"date_published":"2018-06-27T00:00:00Z","day":"27","doi":"10.15479/AT:ISTA:th_1032","title":"From the left to the right: A tale of asymmetries, environments, and hippocampal development","has_accepted_license":"1","publication_identifier":{"issn":["2663-337X"]},"year":"2018","degree_awarded":"PhD","oa":1,"supervisor":[{"full_name":"Shigemoto, Ryuichi","first_name":"Ryuichi","last_name":"Shigemoto","orcid":"0000-0001-8761-9444","id":"499F3ABC-F248-11E8-B48F-1D18A9856A87"}],"status":"public","pubrep_id":"1032","date_updated":"2023-09-07T12:39:22Z"},{"publication_status":"published","citation":{"chicago":"Altmeyer, Sebastian. “Non-Linear Dynamics and Alternating ‘Flip’ Solutions in Ferrofluidic Taylor-Couette Flow.” <i>Journal of Magnetism and Magnetic Materials</i>. Elsevier, 2018. <a href=\"https://doi.org/10.1016/j.jmmm.2017.12.073\">https://doi.org/10.1016/j.jmmm.2017.12.073</a>.","ama":"Altmeyer S. Non-linear dynamics and alternating ‘flip’ solutions in ferrofluidic Taylor-Couette flow. <i>Journal of Magnetism and Magnetic Materials</i>. 2018;452:427-441. doi:<a href=\"https://doi.org/10.1016/j.jmmm.2017.12.073\">10.1016/j.jmmm.2017.12.073</a>","apa":"Altmeyer, S. (2018). Non-linear dynamics and alternating ‘flip’ solutions in ferrofluidic Taylor-Couette flow. <i>Journal of Magnetism and Magnetic Materials</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.jmmm.2017.12.073\">https://doi.org/10.1016/j.jmmm.2017.12.073</a>","ista":"Altmeyer S. 2018. Non-linear dynamics and alternating ‘flip’ solutions in ferrofluidic Taylor-Couette flow. Journal of Magnetism and Magnetic Materials. 452, 427–441.","short":"S. Altmeyer, Journal of Magnetism and Magnetic Materials 452 (2018) 427–441.","mla":"Altmeyer, Sebastian. “Non-Linear Dynamics and Alternating ‘Flip’ Solutions in Ferrofluidic Taylor-Couette Flow.” <i>Journal of Magnetism and Magnetic Materials</i>, vol. 452, Elsevier, 2018, pp. 427–41, doi:<a href=\"https://doi.org/10.1016/j.jmmm.2017.12.073\">10.1016/j.jmmm.2017.12.073</a>.","ieee":"S. Altmeyer, “Non-linear dynamics and alternating ‘flip’ solutions in ferrofluidic Taylor-Couette flow,” <i>Journal of Magnetism and Magnetic Materials</i>, vol. 452. Elsevier, pp. 427–441, 2018."},"quality_controlled":"1","oa_version":"Submitted Version","file":[{"file_name":"2018_Magnetism_Altmeyer.pdf","file_size":17309535,"checksum":"431f5cd4a628d7ca21161f82b14ccb4f","relation":"main_file","access_level":"open_access","date_updated":"2020-07-14T12:46:37Z","creator":"dernst","content_type":"application/pdf","file_id":"7838","date_created":"2020-05-14T14:41:17Z"}],"department":[{"_id":"BjHo"}],"article_type":"original","date_published":"2018-04-15T00:00:00Z","doi":"10.1016/j.jmmm.2017.12.073","day":"15","isi":1,"has_accepted_license":"1","title":"Non-linear dynamics and alternating ‘flip’ solutions in ferrofluidic Taylor-Couette flow","year":"2018","external_id":{"isi":["000425547700061"]},"oa":1,"intvolume":"       452","status":"public","date_updated":"2023-09-13T09:03:44Z","abstract":[{"text":"This study treats with the influence of a symmetry-breaking transversal magnetic field on the nonlinear dynamics of ferrofluidic Taylor-Couette flow – flow confined between two concentric independently rotating cylinders. We detected alternating ‘flip’ solutions which are flow states featuring typical characteristics of slow-fast-dynamics in dynamical systems. The flip corresponds to a temporal change in the axial wavenumber and we find them to appear either as pure 2-fold axisymmetric (due to the symmetry-breaking nature of the applied transversal magnetic field) or involving non-axisymmetric, helical modes in its interim solution. The latter ones show features of typical ribbon solutions. In any case the flip solutions have a preferential first axial wavenumber which corresponds to the more stable state (slow dynamics) and second axial wavenumber, corresponding to the short appearing more unstable state (fast dynamics). However, in both cases the flip time grows exponential with increasing the magnetic field strength before the flip solutions, living on 2-tori invariant manifolds, cease to exist, with lifetime going to infinity. Further we show that ferrofluidic flow turbulence differ from the classical, ordinary (usually at high Reynolds number) turbulence. The applied magnetic field hinders the free motion of ferrofluid partials and therefore smoothen typical turbulent quantities and features so that speaking of mildly chaotic dynamics seems to be a more appropriate expression for the observed motion. ","lang":"eng"}],"acknowledgement":"S.Altmeyer is a Serra Húnter Fellow","_id":"519","publisher":"Elsevier","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","publist_id":"7297","file_date_updated":"2020-07-14T12:46:37Z","ddc":["530"],"volume":452,"date_created":"2018-12-11T11:46:56Z","page":"427 - 441","type":"journal_article","month":"04","author":[{"last_name":"Altmeyer","full_name":"Altmeyer, Sebastian","first_name":"Sebastian","id":"2EE67FDC-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-5964-0203"}],"language":[{"iso":"eng"}],"scopus_import":"1","publication":"Journal of Magnetism and Magnetic Materials","article_processing_charge":"No"},{"citation":{"mla":"Moser, Thomas. <i>Point Interactions in Systems of Fermions</i>. Institute of Science and Technology Austria, 2018, doi:<a href=\"https://doi.org/10.15479/AT:ISTA:th_1043\">10.15479/AT:ISTA:th_1043</a>.","short":"T. Moser, Point Interactions in Systems of Fermions, Institute of Science and Technology Austria, 2018.","ieee":"T. Moser, “Point interactions in systems of fermions,” Institute of Science and Technology Austria, 2018.","ista":"Moser T. 2018. Point interactions in systems of fermions. Institute of Science and Technology Austria.","ama":"Moser T. Point interactions in systems of fermions. 2018. doi:<a href=\"https://doi.org/10.15479/AT:ISTA:th_1043\">10.15479/AT:ISTA:th_1043</a>","apa":"Moser, T. (2018). <i>Point interactions in systems of fermions</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT:ISTA:th_1043\">https://doi.org/10.15479/AT:ISTA:th_1043</a>","chicago":"Moser, Thomas. “Point Interactions in Systems of Fermions.” Institute of Science and Technology Austria, 2018. <a href=\"https://doi.org/10.15479/AT:ISTA:th_1043\">https://doi.org/10.15479/AT:ISTA:th_1043</a>."},"publication_status":"published","date_published":"2018-09-04T00:00:00Z","department":[{"_id":"RoSe"}],"oa_version":"Published Version","file":[{"date_updated":"2020-07-14T12:46:37Z","file_name":"2018_Thesis_Moser.pdf","access_level":"open_access","relation":"main_file","checksum":"fbd8c747d148b468a21213b7cf175225","file_size":851164,"file_id":"6256","content_type":"application/pdf","date_created":"2019-04-09T07:45:38Z","creator":"dernst"},{"date_created":"2019-04-09T07:45:38Z","content_type":"application/zip","file_id":"6257","creator":"dernst","date_updated":"2020-07-14T12:46:37Z","file_size":1531516,"checksum":"c28e16ecfc1126d3ce324ec96493c01e","relation":"source_file","access_level":"closed","file_name":"2018_Thesis_Moser_Source.zip"}],"degree_awarded":"PhD","year":"2018","has_accepted_license":"1","title":"Point interactions in systems of fermions","publication_identifier":{"issn":["2663-337X"]},"doi":"10.15479/AT:ISTA:th_1043","day":"04","date_updated":"2023-09-27T12:34:14Z","pubrep_id":"1043","status":"public","supervisor":[{"id":"4AFD0470-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-6781-0521","last_name":"Seiringer","first_name":"Robert","full_name":"Seiringer, Robert"}],"oa":1,"alternative_title":["ISTA Thesis"],"_id":"52","abstract":[{"text":"In this thesis we will discuss systems of point interacting fermions, their stability and other spectral properties. Whereas for bosons a point interacting system is always unstable this ques- tion is more subtle for a gas of two species of fermions. In particular the answer depends on the mass ratio between these two species. Most of this work will be focused on the N + M model which consists of two species of fermions with N, M particles respectively which interact via point interactions. We will introduce this model using a formal limit and discuss the N + 1 system in more detail. In particular, we will show that for mass ratios above a critical one, which does not depend on the particle number, the N + 1 system is stable. In the context of this model we will prove rigorous versions of Tan relations which relate various quantities of the point-interacting model. By restricting the N + 1 system to a box we define a finite density model with point in- teractions. In the context of this system we will discuss the energy change when introducing a point-interacting impurity into a system of non-interacting fermions. We will see that this change in energy is bounded independently of the particle number and in particular the bound only depends on the density and the scattering length. As another special case of the N + M model we will show stability of the 2 + 2 model for mass ratios in an interval around one. Further we will investigate a different model of point interactions which was discussed before in the literature and which is, contrary to the N + M model, not given by a limiting procedure but is based on a Dirichlet form. We will show that this system behaves trivially in the thermodynamic limit, i.e. the free energy per particle is the same as the one of the non-interacting system.","lang":"eng"}],"publist_id":"8002","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","project":[{"_id":"25C878CE-B435-11E9-9278-68D0E5697425","name":"Structure of the Excitation Spectrum for Many-Body Quantum Systems","grant_number":"P27533_N27","call_identifier":"FWF"}],"publisher":"Institute of Science and Technology Austria","page":"115","date_created":"2018-12-11T11:44:22Z","related_material":{"record":[{"relation":"part_of_dissertation","id":"5856","status":"public"},{"status":"public","relation":"part_of_dissertation","id":"154"},{"relation":"part_of_dissertation","id":"1198","status":"public"},{"id":"741","relation":"part_of_dissertation","status":"public"}]},"file_date_updated":"2020-07-14T12:46:37Z","ddc":["515","530","519"],"article_processing_charge":"No","type":"dissertation","language":[{"iso":"eng"}],"month":"09","author":[{"id":"2B5FC9A4-F248-11E8-B48F-1D18A9856A87","last_name":"Moser","first_name":"Thomas","full_name":"Moser, Thomas"}]},{"_id":"53","abstract":[{"text":"In 2013, a publication repository was implemented at IST Austria and 2015 after a thorough preparation phase a data repository was implemented - both based on the Open Source Software EPrints. In this text, designed as field report, we will reflect on our experiences with Open Source Software in general and specifically with EPrints regarding technical aspects but also regarding their characteristics of the user community. The second part is a pleading for including the end users in the process of implementation, adaption and evaluation.","lang":"eng"}],"publist_id":"8001","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","publisher":"Vereinigung Österreichischer Bibliothekarinnen und Bibliothekare","page":"199 - 206","date_created":"2018-12-11T11:44:22Z","file_date_updated":"2020-07-14T12:46:38Z","volume":71,"ddc":["020"],"publication":"VÖB Mitteilungen","scopus_import":1,"type":"journal_article","month":"10","language":[{"iso":"eng"}],"author":[{"id":"406048EC-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-2724-4614","last_name":"Petritsch","full_name":"Petritsch, Barbara","first_name":"Barbara"},{"id":"3252EDC2-F248-11E8-B48F-1D18A9856A87","last_name":"Porsche","first_name":"Jana","full_name":"Porsche, Jana"}],"publication_status":"published","citation":{"chicago":"Petritsch, Barbara, and Jana Porsche. “IST PubRep and IST DataRep: The Institutional Repositories at IST Austria.” <i>VÖB Mitteilungen</i>. Vereinigung Österreichischer Bibliothekarinnen und Bibliothekare, 2018. <a href=\"https://doi.org/10.31263/voebm.v71i1.1993\">https://doi.org/10.31263/voebm.v71i1.1993</a>.","apa":"Petritsch, B., &#38; Porsche, J. (2018). IST PubRep and IST DataRep: the institutional repositories at IST Austria. <i>VÖB Mitteilungen</i>. Vereinigung Österreichischer Bibliothekarinnen und Bibliothekare. <a href=\"https://doi.org/10.31263/voebm.v71i1.1993\">https://doi.org/10.31263/voebm.v71i1.1993</a>","ama":"Petritsch B, Porsche J. IST PubRep and IST DataRep: the institutional repositories at IST Austria. <i>VÖB Mitteilungen</i>. 2018;71(1):199-206. doi:<a href=\"https://doi.org/10.31263/voebm.v71i1.1993\">10.31263/voebm.v71i1.1993</a>","ista":"Petritsch B, Porsche J. 2018. IST PubRep and IST DataRep: the institutional repositories at IST Austria. VÖB Mitteilungen. 71(1), 199–206.","mla":"Petritsch, Barbara, and Jana Porsche. “IST PubRep and IST DataRep: The Institutional Repositories at IST Austria.” <i>VÖB Mitteilungen</i>, vol. 71, no. 1, Vereinigung Österreichischer Bibliothekarinnen und Bibliothekare, 2018, pp. 199–206, doi:<a href=\"https://doi.org/10.31263/voebm.v71i1.1993\">10.31263/voebm.v71i1.1993</a>.","short":"B. Petritsch, J. Porsche, VÖB Mitteilungen 71 (2018) 199–206.","ieee":"B. Petritsch and J. Porsche, “IST PubRep and IST DataRep: the institutional repositories at IST Austria,” <i>VÖB Mitteilungen</i>, vol. 71, no. 1. Vereinigung Österreichischer Bibliothekarinnen und Bibliothekare, pp. 199–206, 2018."},"date_published":"2018-10-01T00:00:00Z","department":[{"_id":"E-Lib"}],"oa_version":"Published Version","file":[{"date_created":"2018-12-17T12:40:27Z","file_id":"5702","content_type":"application/pdf","creator":"dernst","date_updated":"2020-07-14T12:46:38Z","access_level":"open_access","relation":"main_file","checksum":"7ac61bade5f37db011ca435ebcf86797","file_size":509434,"file_name":"2018_VOEB_Petritsch.pdf"}],"year":"2018","title":"IST PubRep and IST DataRep: the institutional repositories at IST Austria","has_accepted_license":"1","issue":"1","day":"01","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"doi":"10.31263/voebm.v71i1.1993","date_updated":"2021-01-12T08:01:26Z","intvolume":"        71","status":"public","oa":1},{"date_published":"2018-03-01T00:00:00Z","department":[{"_id":"HeEd"}],"file":[{"creator":"dernst","file_id":"5953","content_type":"application/pdf","date_created":"2019-02-12T06:47:52Z","file_name":"2018_Edelsbrunner.pdf","access_level":"open_access","relation":"main_file","checksum":"1c8d58cd489a66cd3e2064c1141c8c5e","file_size":708357,"date_updated":"2020-07-14T12:46:38Z"}],"oa_version":"Preprint","quality_controlled":"1","publication_status":"published","citation":{"ista":"Edelsbrunner H, Iglesias Ham M. 2018. Multiple covers with balls I: Inclusion–exclusion. Computational Geometry: Theory and Applications. 68, 119–133.","ieee":"H. Edelsbrunner and M. Iglesias Ham, “Multiple covers with balls I: Inclusion–exclusion,” <i>Computational Geometry: Theory and Applications</i>, vol. 68. Elsevier, pp. 119–133, 2018.","short":"H. Edelsbrunner, M. Iglesias Ham, Computational Geometry: Theory and Applications 68 (2018) 119–133.","mla":"Edelsbrunner, Herbert, and Mabel Iglesias Ham. “Multiple Covers with Balls I: Inclusion–Exclusion.” <i>Computational Geometry: Theory and Applications</i>, vol. 68, Elsevier, 2018, pp. 119–33, doi:<a href=\"https://doi.org/10.1016/j.comgeo.2017.06.014\">10.1016/j.comgeo.2017.06.014</a>.","chicago":"Edelsbrunner, Herbert, and Mabel Iglesias Ham. “Multiple Covers with Balls I: Inclusion–Exclusion.” <i>Computational Geometry: Theory and Applications</i>. Elsevier, 2018. <a href=\"https://doi.org/10.1016/j.comgeo.2017.06.014\">https://doi.org/10.1016/j.comgeo.2017.06.014</a>.","ama":"Edelsbrunner H, Iglesias Ham M. Multiple covers with balls I: Inclusion–exclusion. <i>Computational Geometry: Theory and Applications</i>. 2018;68:119-133. doi:<a href=\"https://doi.org/10.1016/j.comgeo.2017.06.014\">10.1016/j.comgeo.2017.06.014</a>","apa":"Edelsbrunner, H., &#38; Iglesias Ham, M. (2018). Multiple covers with balls I: Inclusion–exclusion. <i>Computational Geometry: Theory and Applications</i>. Elsevier. <a href=\"https://doi.org/10.1016/j.comgeo.2017.06.014\">https://doi.org/10.1016/j.comgeo.2017.06.014</a>"},"date_updated":"2023-09-13T08:59:00Z","status":"public","intvolume":"        68","oa":1,"external_id":{"isi":["000415778300010"]},"year":"2018","title":"Multiple covers with balls I: Inclusion–exclusion","has_accepted_license":"1","isi":1,"doi":"10.1016/j.comgeo.2017.06.014","day":"01","ec_funded":1,"publist_id":"7289","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","publisher":"Elsevier","project":[{"_id":"255D761E-B435-11E9-9278-68D0E5697425","name":"Topological Complex Systems","grant_number":"318493","call_identifier":"FP7"}],"_id":"530","abstract":[{"text":"Inclusion–exclusion is an effective method for computing the volume of a union of measurable sets. We extend it to multiple coverings, proving short inclusion–exclusion formulas for the subset of Rn covered by at least k balls in a finite set. We implement two of the formulas in dimension n=3 and report on results obtained with our software.","lang":"eng"}],"article_processing_charge":"No","publication":"Computational Geometry: Theory and Applications","scopus_import":"1","month":"03","author":[{"id":"3FB178DA-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-9823-6833","first_name":"Herbert","full_name":"Edelsbrunner, Herbert","last_name":"Edelsbrunner"},{"last_name":"Iglesias Ham","full_name":"Iglesias Ham, Mabel","first_name":"Mabel","id":"41B58C0C-F248-11E8-B48F-1D18A9856A87"}],"language":[{"iso":"eng"}],"type":"journal_article","page":"119 - 133","date_created":"2018-12-11T11:46:59Z","ddc":["000"],"volume":68,"file_date_updated":"2020-07-14T12:46:38Z"},{"date_published":"2018-11-01T00:00:00Z","oa_version":"Published Version","file":[{"creator":"dernst","file_id":"5867","content_type":"application/pdf","date_created":"2019-01-22T07:25:51Z","file_name":"2017_DistribComp_Alistarh.pdf","relation":"main_file","access_level":"open_access","file_size":595707,"checksum":"69b46e537acdcac745237ddb853fcbb5","date_updated":"2020-07-14T12:46:38Z"}],"department":[{"_id":"DaAl"}],"quality_controlled":"1","publication_status":"published","citation":{"ieee":"D.-A. Alistarh, J. Aspnes, V. King, and J. Saia, “Communication-efficient randomized consensus,” <i>Distributed Computing</i>, vol. 31, no. 6. Springer, pp. 489–501, 2018.","mla":"Alistarh, Dan-Adrian, et al. “Communication-Efficient Randomized Consensus.” <i>Distributed Computing</i>, vol. 31, no. 6, Springer, 2018, pp. 489–501, doi:<a href=\"https://doi.org/10.1007/s00446-017-0315-1\">10.1007/s00446-017-0315-1</a>.","short":"D.-A. Alistarh, J. Aspnes, V. King, J. Saia, Distributed Computing 31 (2018) 489–501.","ista":"Alistarh D-A, Aspnes J, King V, Saia J. 2018. Communication-efficient randomized consensus. Distributed Computing. 31(6), 489–501.","apa":"Alistarh, D.-A., Aspnes, J., King, V., &#38; Saia, J. (2018). Communication-efficient randomized consensus. <i>Distributed Computing</i>. Springer. <a href=\"https://doi.org/10.1007/s00446-017-0315-1\">https://doi.org/10.1007/s00446-017-0315-1</a>","ama":"Alistarh D-A, Aspnes J, King V, Saia J. Communication-efficient randomized consensus. <i>Distributed Computing</i>. 2018;31(6):489-501. doi:<a href=\"https://doi.org/10.1007/s00446-017-0315-1\">10.1007/s00446-017-0315-1</a>","chicago":"Alistarh, Dan-Adrian, James Aspnes, Valerie King, and Jared Saia. “Communication-Efficient Randomized Consensus.” <i>Distributed Computing</i>. Springer, 2018. <a href=\"https://doi.org/10.1007/s00446-017-0315-1\">https://doi.org/10.1007/s00446-017-0315-1</a>."},"status":"public","intvolume":"        31","date_updated":"2023-02-23T12:23:25Z","oa":1,"year":"2018","day":"01","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"doi":"10.1007/s00446-017-0315-1","issue":"6","publication_identifier":{"issn":["01782770"]},"title":"Communication-efficient randomized consensus","has_accepted_license":"1","publist_id":"7281","publisher":"Springer","project":[{"name":"IST Austria Open Access Fund","_id":"B67AFEDC-15C9-11EA-A837-991A96BB2854"}],"user_id":"3E5EF7F0-F248-11E8-B48F-1D18A9856A87","_id":"536","abstract":[{"text":"We consider the problem of consensus in the challenging classic model. In this model, the adversary is adaptive; it can choose which processors crash at any point during the course of the algorithm. Further, communication is via asynchronous message passing: there is no known upper bound on the time to send a message from one processor to another, and all messages and coin flips are seen by the adversary. We describe a new randomized consensus protocol with expected message complexity O(n2log2n) when fewer than n / 2 processes may fail by crashing. This is an almost-linear improvement over the best previously known protocol, and within logarithmic factors of a known Ω(n2) message lower bound. The protocol further ensures that no process sends more than O(nlog3n) messages in expectation, which is again within logarithmic factors of optimal. We also present a generalization of the algorithm to an arbitrary number of failures t, which uses expected O(nt+t2log2t) total messages. Our approach is to build a message-efficient, resilient mechanism for aggregating individual processor votes, implementing the message-passing equivalent of a weak shared coin. Roughly, in our protocol, a processor first announces its votes to small groups, then propagates them to increasingly larger groups as it generates more and more votes. To bound the number of messages that an individual process might have to send or receive, the protocol progressively increases the weight of generated votes. The main technical challenge is bounding the impact of votes that are still “in flight” (generated, but not fully propagated) on the final outcome of the shared coin, especially since such votes might have different weights. We achieve this by leveraging the structure of the algorithm, and a technical argument based on martingale concentration bounds. Overall, we show that it is possible to build an efficient message-passing implementation of a shared coin, and in the process (almost-optimally) solve the classic consensus problem in the asynchronous message-passing model.","lang":"eng"}],"scopus_import":1,"article_processing_charge":"Yes (via OA deal)","publication":"Distributed Computing","language":[{"iso":"eng"}],"month":"11","author":[{"id":"4A899BFC-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-3650-940X","last_name":"Alistarh","first_name":"Dan-Adrian","full_name":"Alistarh, Dan-Adrian"},{"first_name":"James","full_name":"Aspnes, James","last_name":"Aspnes"},{"last_name":"King","first_name":"Valerie","full_name":"King, Valerie"},{"full_name":"Saia, Jared","first_name":"Jared","last_name":"Saia"}],"type":"journal_article","date_created":"2018-12-11T11:47:01Z","page":"489-501","ddc":["000"],"volume":31,"file_date_updated":"2020-07-14T12:46:38Z"},{"publist_id":"7277","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","publisher":"Institute of Science and Technology Austria","_id":"539","alternative_title":["ISTA Thesis"],"abstract":[{"lang":"eng","text":"The whole life cycle of plants as well as their responses to environmental stimuli is governed by a complex network of hormonal regulations. A number of studies have demonstrated an essential role of both auxin and cytokinin in the regulation of many aspects of plant growth and development including embryogenesis, postembryonic organogenic processes such as root, and shoot branching, root and shoot apical meristem activity and phyllotaxis. Over the last decades essential knowledge on the key molecular factors and pathways that spatio-temporally define auxin and cytokinin activities in the plant body has accumulated. However, how both hormonal pathways are interconnected by a complex network of interactions and feedback circuits that determines the final outcome of the individual hormone actions is still largely unknown. Root system architecture establishment and in particular formation of lateral organs is prime example of developmental process at whose regulation both auxin and cytokinin pathways converge. To dissect convergence points and pathways that tightly balance auxin - cytokinin antagonistic activities that determine the root branching pattern transcriptome profiling was applied. Genome wide expression analyses of the xylem pole pericycle, a tissue giving rise to lateral roots, led to identification of genes that are highly responsive to combinatorial auxin and cytokinin treatments and play an essential function in the auxin-cytokinin regulated root branching. SYNERGISTIC AUXIN CYTOKININ 1 (SYAC1) gene, which encodes for a protein of unknown function, was detected among the top candidate genes of which expression was synergistically up-regulated by simultaneous hormonal treatment. Plants with modulated SYAC1 activity exhibit severe defects in the root system establishment and attenuate developmental responses to both auxin and cytokinin. To explore the biological function of the SYAC1, we employed different strategies including expression pattern analysis, subcellular localization and phenotypic analyses of the syac1 loss-of-function and gain-of-function transgenic lines along with the identification of the SYAC1 interaction partners. Detailed functional characterization revealed that SYAC1 acts as a developmentally specific regulator of the secretory pathway to control deposition of cell wall components and thereby rapidly fine tune elongation growth."}],"article_processing_charge":"No","month":"01","author":[{"full_name":"Hurny, Andrej","first_name":"Andrej","last_name":"Hurny","id":"4DC4AF46-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-3638-1426"}],"language":[{"iso":"eng"}],"type":"dissertation","page":"147","date_created":"2018-12-11T11:47:03Z","ddc":["570"],"file_date_updated":"2020-12-02T23:30:08Z","related_material":{"record":[{"status":"public","id":"1024","relation":"part_of_dissertation"}]},"date_published":"2018-01-01T00:00:00Z","department":[{"_id":"EvBe"}],"oa_version":"Published Version","file":[{"creator":"dernst","content_type":"application/vnd.openxmlformats-officedocument.wordprocessingml.document","file_id":"6226","date_created":"2019-04-05T09:37:56Z","file_name":"2018_Hurny_thesis_source.docx","embargo_to":"open_access","file_size":28112114,"checksum":"0c9d6d1c80d9857e6e545213467bbcb2","relation":"source_file","access_level":"closed","date_updated":"2020-12-02T23:30:08Z"},{"file_id":"6227","content_type":"application/pdf","date_created":"2019-04-05T09:37:55Z","creator":"dernst","date_updated":"2020-12-02T09:52:16Z","embargo":"2019-07-10","file_name":"2018_Hurny_thesis.pdf","access_level":"open_access","relation":"main_file","file_size":12524427,"checksum":"ecbe481a1413d270bd501b872c7ed54f"}],"citation":{"ista":"Hurny A. 2018. Identification and characterization of novel auxin-cytokinin cross-talk components. Institute of Science and Technology Austria.","mla":"Hurny, Andrej. <i>Identification and Characterization of Novel Auxin-Cytokinin Cross-Talk Components</i>. Institute of Science and Technology Austria, 2018, doi:<a href=\"https://doi.org/10.15479/AT:ISTA:th_930\">10.15479/AT:ISTA:th_930</a>.","short":"A. Hurny, Identification and Characterization of Novel Auxin-Cytokinin Cross-Talk Components, Institute of Science and Technology Austria, 2018.","ieee":"A. Hurny, “Identification and characterization of novel auxin-cytokinin cross-talk components,” Institute of Science and Technology Austria, 2018.","chicago":"Hurny, Andrej. “Identification and Characterization of Novel Auxin-Cytokinin Cross-Talk Components.” Institute of Science and Technology Austria, 2018. <a href=\"https://doi.org/10.15479/AT:ISTA:th_930\">https://doi.org/10.15479/AT:ISTA:th_930</a>.","apa":"Hurny, A. (2018). <i>Identification and characterization of novel auxin-cytokinin cross-talk components</i>. Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT:ISTA:th_930\">https://doi.org/10.15479/AT:ISTA:th_930</a>","ama":"Hurny A. Identification and characterization of novel auxin-cytokinin cross-talk components. 2018. doi:<a href=\"https://doi.org/10.15479/AT:ISTA:th_930\">10.15479/AT:ISTA:th_930</a>"},"publication_status":"published","pubrep_id":"930","date_updated":"2023-09-07T12:41:06Z","status":"public","oa":1,"supervisor":[{"id":"38F4F166-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8510-9739","full_name":"Benková, Eva","first_name":"Eva","last_name":"Benková"}],"degree_awarded":"PhD","year":"2018","title":"Identification and characterization of novel auxin-cytokinin cross-talk components","has_accepted_license":"1","publication_identifier":{"issn":["2663-337X"]},"tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"day":"01","doi":"10.15479/AT:ISTA:th_930"},{"department":[{"_id":"CaHe"}],"oa_version":"Published Version","date_published":"2018-10-08T00:00:00Z","article_type":"review","publication_status":"published","citation":{"ieee":"D. C. Nunes Pinheiro and Y. Bellaïche, “Mechanical force-driven adherents junction remodeling and epithelial dynamics,” <i>Developmental Cell</i>, vol. 47, no. 1. Cell Press, pp. 3–19, 2018.","short":"D.C. Nunes Pinheiro, Y. Bellaïche, Developmental Cell 47 (2018) 3–19.","mla":"Nunes Pinheiro, Diana C., and Yohanns Bellaïche. “Mechanical Force-Driven Adherents Junction Remodeling and Epithelial Dynamics.” <i>Developmental Cell</i>, vol. 47, no. 1, Cell Press, 2018, pp. 3–19, doi:<a href=\"https://doi.org/10.1016/j.devcel.2018.09.014\">10.1016/j.devcel.2018.09.014</a>.","ista":"Nunes Pinheiro DC, Bellaïche Y. 2018. Mechanical force-driven adherents junction remodeling and epithelial dynamics. Developmental Cell. 47(1), 3–19.","ama":"Nunes Pinheiro DC, Bellaïche Y. Mechanical force-driven adherents junction remodeling and epithelial dynamics. <i>Developmental Cell</i>. 2018;47(1):3-19. doi:<a href=\"https://doi.org/10.1016/j.devcel.2018.09.014\">10.1016/j.devcel.2018.09.014</a>","apa":"Nunes Pinheiro, D. C., &#38; Bellaïche, Y. (2018). Mechanical force-driven adherents junction remodeling and epithelial dynamics. <i>Developmental Cell</i>. Cell Press. <a href=\"https://doi.org/10.1016/j.devcel.2018.09.014\">https://doi.org/10.1016/j.devcel.2018.09.014</a>","chicago":"Nunes Pinheiro, Diana C, and Yohanns Bellaïche. “Mechanical Force-Driven Adherents Junction Remodeling and Epithelial Dynamics.” <i>Developmental Cell</i>. Cell Press, 2018. <a href=\"https://doi.org/10.1016/j.devcel.2018.09.014\">https://doi.org/10.1016/j.devcel.2018.09.014</a>."},"quality_controlled":"1","external_id":{"isi":["000446579900002"]},"date_updated":"2023-09-13T08:54:38Z","status":"public","intvolume":"        47","title":"Mechanical force-driven adherents junction remodeling and epithelial dynamics","issue":"1","isi":1,"day":"08","doi":"10.1016/j.devcel.2018.09.014","year":"2018","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","publisher":"Cell Press","main_file_link":[{"url":"https://doi.org/10.1016/j.devcel.2018.09.014"}],"publist_id":"8000","abstract":[{"text":"During epithelial tissue development, repair, and homeostasis, adherens junctions (AJs) ensure intercellular adhesion and tissue integrity while allowing for cell and tissue dynamics. Mechanical forces play critical roles in AJs’ composition and dynamics. Recent findings highlight that beyond a well-established role in reinforcing cell-cell adhesion, AJ mechanosensitivity promotes junctional remodeling and polarization, thereby regulating critical processes such as cell intercalation, division, and collective migration. Here, we provide an integrated view of mechanosensing mechanisms that regulate cell-cell contact composition, geometry, and integrity under tension and highlight pivotal roles for mechanosensitive AJ remodeling in preserving epithelial integrity and sustaining tissue dynamics.","lang":"eng"}],"_id":"54","acknowledgement":"Research in the Bellaïche laboratory is supported by the European Research Council (ERC Advanced, TiMoprh, 340784), the Fondation ARC pour la Recherche sur le Cancer (SL220130607097), the Agence Nationale de la Recherche (ANR lLabex DEEP; 11-LBX-0044, ANR-10-IDEX-0001-02), the Centre National de la Recherche Scientifique, the Institut National de la Santé et de la Recherche Médicale, and Institut Curie and PSL Research University funding or grants.","month":"10","language":[{"iso":"eng"}],"author":[{"last_name":"Nunes Pinheiro","first_name":"Diana C","full_name":"Nunes Pinheiro, Diana C","orcid":"0000-0003-4333-7503","id":"2E839F16-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Bellaïche, Yohanns","first_name":"Yohanns","last_name":"Bellaïche"}],"type":"journal_article","article_processing_charge":"No","publication":"Developmental Cell","scopus_import":"1","volume":47,"page":"3 - 19","date_created":"2018-12-11T11:44:23Z"},{"_id":"542","abstract":[{"text":"The t-haplotype, a mouse meiotic driver found on chromosome 17, has been a model for autosomal segregation distortion for close to a century, but several questions remain regarding its biology and evolutionary history. A recently published set of population genomics resources for wild mice includes several individuals heterozygous for the t-haplotype, which we use to characterize this selfish element at the genomic and transcriptomic level. Our results show that large sections of the t-haplotype have been replaced by standard homologous sequences, possibly due to occasional events of recombination, and that this complicates the inference of its history. As expected for a long genomic segment of very low recombination, the t-haplotype carries an excess of fixed nonsynonymous mutations compared to the standard chromosome. This excess is stronger for regions that have not undergone recent recombination, suggesting that occasional gene flow between the t and the standard chromosome may provide a mechanism to regenerate coding sequences that have accumulated deleterious mutations. Finally, we find that t-complex genes with altered expression largely overlap with deleted or amplified regions, and that carrying a t-haplotype alters the testis expression of genes outside of the t-complex, providing new leads into the pathways involved in the biology of this segregation distorter.","lang":"eng"}],"ec_funded":1,"publist_id":"7274","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","publisher":"Genetics Society of America","project":[{"name":"Prevalence and Influence of Sexual Antagonism on Genome Evolution","_id":"250BDE62-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","grant_number":"715257"}],"page":"365 - 375","date_created":"2018-12-11T11:47:04Z","volume":208,"ddc":["576"],"related_material":{"record":[{"status":"public","id":"5571","relation":"popular_science"},{"status":"public","relation":"popular_science","id":"5572"}]},"file_date_updated":"2020-07-14T12:46:50Z","article_processing_charge":"No","publication":"Genetics","scopus_import":"1","language":[{"iso":"eng"}],"month":"01","author":[{"first_name":"Réka K","full_name":"Kelemen, Réka K","last_name":"Kelemen","id":"48D3F8DE-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8489-9281"},{"first_name":"Beatriz","full_name":"Vicoso, Beatriz","last_name":"Vicoso","id":"49E1C5C6-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-4579-8306"}],"type":"journal_article","quality_controlled":"1","publication_status":"published","citation":{"ama":"Kelemen RK, Vicoso B. Complex history and differentiation patterns of the t-haplotype, a mouse meiotic driver. <i>Genetics</i>. 2018;208(1):365-375. doi:<a href=\"https://doi.org/10.1534/genetics.117.300513\">10.1534/genetics.117.300513</a>","apa":"Kelemen, R. K., &#38; Vicoso, B. (2018). Complex history and differentiation patterns of the t-haplotype, a mouse meiotic driver. <i>Genetics</i>. Genetics Society of America. <a href=\"https://doi.org/10.1534/genetics.117.300513\">https://doi.org/10.1534/genetics.117.300513</a>","chicago":"Kelemen, Réka K, and Beatriz Vicoso. “Complex History and Differentiation Patterns of the T-Haplotype, a Mouse Meiotic Driver.” <i>Genetics</i>. Genetics Society of America, 2018. <a href=\"https://doi.org/10.1534/genetics.117.300513\">https://doi.org/10.1534/genetics.117.300513</a>.","ieee":"R. K. Kelemen and B. Vicoso, “Complex history and differentiation patterns of the t-haplotype, a mouse meiotic driver,” <i>Genetics</i>, vol. 208, no. 1. Genetics Society of America, pp. 365–375, 2018.","mla":"Kelemen, Réka K., and Beatriz Vicoso. “Complex History and Differentiation Patterns of the T-Haplotype, a Mouse Meiotic Driver.” <i>Genetics</i>, vol. 208, no. 1, Genetics Society of America, 2018, pp. 365–75, doi:<a href=\"https://doi.org/10.1534/genetics.117.300513\">10.1534/genetics.117.300513</a>.","short":"R.K. Kelemen, B. Vicoso, Genetics 208 (2018) 365–375.","ista":"Kelemen RK, Vicoso B. 2018. Complex history and differentiation patterns of the t-haplotype, a mouse meiotic driver. Genetics. 208(1), 365–375."},"date_published":"2018-01-01T00:00:00Z","article_type":"original","department":[{"_id":"BeVi"}],"file":[{"date_created":"2018-12-12T10:15:14Z","file_id":"5132","content_type":"application/pdf","creator":"system","date_updated":"2020-07-14T12:46:50Z","relation":"main_file","access_level":"open_access","checksum":"2123845e7031a0cf043905be160f9e69","file_size":1311661,"file_name":"IST-2018-1058-v1+1_365.full__1_.pdf"}],"oa_version":"Published Version","year":"2018","has_accepted_license":"1","title":"Complex history and differentiation patterns of the t-haplotype, a mouse meiotic driver","issue":"1","isi":1,"doi":"10.1534/genetics.117.300513","tmp":{"legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode","short":"CC BY (4.0)","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","image":"/images/cc_by.png"},"day":"01","pubrep_id":"1058","date_updated":"2024-02-21T13:48:27Z","status":"public","intvolume":"       208","oa":1,"external_id":{"isi":["000419356300024"]}}]