[{"year":"2019","author":[{"full_name":"Cossard, Guillaume","last_name":"Cossard","first_name":"Guillaume"},{"full_name":"Toups, Melissa A","orcid":"0000-0002-9752-7380","id":"4E099E4E-F248-11E8-B48F-1D18A9856A87","first_name":"Melissa A","last_name":"Toups"},{"last_name":"Pannell","first_name":"John ","full_name":"Pannell, John "}],"quality_controlled":"1","citation":{"ista":"Cossard G, Toups MA, Pannell J. 2019. Sexual dimorphism and rapid turnover in gene expression in pre-reproductive seedlings of a dioecious herb. Annals of botany. 123(7), 1119–1131.","short":"G. Cossard, M.A. Toups, J. Pannell, Annals of Botany 123 (2019) 1119–1131.","chicago":"Cossard, Guillaume, Melissa A Toups, and John  Pannell. “Sexual Dimorphism and Rapid Turnover in Gene Expression in Pre-Reproductive Seedlings of a Dioecious Herb.” <i>Annals of Botany</i>. Oxford University Press, 2019. <a href=\"https://doi.org/10.1093/aob/mcy183\">https://doi.org/10.1093/aob/mcy183</a>.","ieee":"G. Cossard, M. A. Toups, and J. Pannell, “Sexual dimorphism and rapid turnover in gene expression in pre-reproductive seedlings of a dioecious herb,” <i>Annals of botany</i>, vol. 123, no. 7. Oxford University Press, pp. 1119–1131, 2019.","ama":"Cossard G, Toups MA, Pannell J. Sexual dimorphism and rapid turnover in gene expression in pre-reproductive seedlings of a dioecious herb. <i>Annals of botany</i>. 2019;123(7):1119-1131. doi:<a href=\"https://doi.org/10.1093/aob/mcy183\">10.1093/aob/mcy183</a>","apa":"Cossard, G., Toups, M. A., &#38; Pannell, J. (2019). Sexual dimorphism and rapid turnover in gene expression in pre-reproductive seedlings of a dioecious herb. <i>Annals of Botany</i>. Oxford University Press. <a href=\"https://doi.org/10.1093/aob/mcy183\">https://doi.org/10.1093/aob/mcy183</a>","mla":"Cossard, Guillaume, et al. “Sexual Dimorphism and Rapid Turnover in Gene Expression in Pre-Reproductive Seedlings of a Dioecious Herb.” <i>Annals of Botany</i>, vol. 123, no. 7, Oxford University Press, 2019, pp. 1119–31, doi:<a href=\"https://doi.org/10.1093/aob/mcy183\">10.1093/aob/mcy183</a>."},"main_file_link":[{"open_access":"1","url":"https://doi.org/10.1093/aob/mcy183"}],"publication_status":"published","abstract":[{"lang":"eng","text":"Sexual dimorphism in morphology, physiology or life history traits is common in dioecious plants at reproductive maturity, but it is typically inconspicuous or absent in juveniles. Although plants of different sexes probably begin to diverge in gene expression both before their reproduction commences and before dimorphism becomes readily apparent, to our knowledge transcriptome-wide differential gene expression has yet to be demonstrated for any angiosperm species."}],"oa":1,"_id":"6710","title":"Sexual dimorphism and rapid turnover in gene expression in pre-reproductive seedlings of a dioecious herb","publication":"Annals of botany","pmid":1,"publisher":"Oxford University Press","article_type":"original","issue":"7","volume":123,"status":"public","date_created":"2019-07-28T21:59:15Z","month":"06","isi":1,"intvolume":"       123","day":"04","type":"journal_article","date_updated":"2023-08-29T06:42:22Z","oa_version":"Published Version","article_processing_charge":"No","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","doi":"10.1093/aob/mcy183","language":[{"iso":"eng"}],"department":[{"_id":"BeVi"}],"page":"1119-1131","date_published":"2019-06-04T00:00:00Z","external_id":{"isi":["000493043500004"],"pmid":["30289430"]},"publication_identifier":{"eissn":["1095-8290"],"issn":["0305-7364"]},"scopus_import":"1"},{"external_id":{"pmid":["31273378"],"isi":["000484039500018"]},"file":[{"access_level":"open_access","checksum":"f9e8f6863a406dcc5a36b2be001c138c","file_name":"2019_GenomeBiology_Picard.pdf","file_id":"6765","date_updated":"2020-07-14T12:47:39Z","content_type":"application/pdf","creator":"dernst","file_size":580205,"date_created":"2019-08-05T07:55:02Z","relation":"main_file"}],"date_published":"2019-07-01T00:00:00Z","page":"1909-1922","scopus_import":"1","publication_identifier":{"eissn":["1759-6653"]},"user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","article_processing_charge":"No","oa_version":"Published Version","type":"journal_article","date_updated":"2023-08-29T06:53:58Z","day":"01","acknowledged_ssus":[{"_id":"CampIT"}],"department":[{"_id":"BeVi"}],"has_accepted_license":"1","doi":"10.1093/gbe/evz133","language":[{"iso":"eng"}],"issue":"7","volume":11,"file_date_updated":"2020-07-14T12:47:39Z","publisher":"Oxford Academic Press","article_type":"original","intvolume":"        11","isi":1,"month":"07","date_created":"2019-08-04T21:59:18Z","status":"public","citation":{"apa":"Picard, M. A. L., Vicoso, B., Roquis, D., Bulla, I., Augusto, R. C., Arancibia, N., … Cosseau, C. (2019). Dosage compensation throughout the Schistosoma mansoni lifecycle: Specific chromatin landscape of the Z chromosome. <i>Genome Biology and Evolution</i>. Oxford Academic Press. <a href=\"https://doi.org/10.1093/gbe/evz133\">https://doi.org/10.1093/gbe/evz133</a>","mla":"Picard, Marion A. L., et al. “Dosage Compensation throughout the Schistosoma Mansoni Lifecycle: Specific Chromatin Landscape of the Z Chromosome.” <i>Genome Biology and Evolution</i>, vol. 11, no. 7, Oxford Academic Press, 2019, pp. 1909–22, doi:<a href=\"https://doi.org/10.1093/gbe/evz133\">10.1093/gbe/evz133</a>.","chicago":"Picard, Marion A L, Beatriz Vicoso, David Roquis, Ingo Bulla, Ronaldo C. Augusto, Nathalie Arancibia, Christoph Grunau, Jérôme Boissier, and Céline Cosseau. “Dosage Compensation throughout the Schistosoma Mansoni Lifecycle: Specific Chromatin Landscape of the Z Chromosome.” <i>Genome Biology and Evolution</i>. Oxford Academic Press, 2019. <a href=\"https://doi.org/10.1093/gbe/evz133\">https://doi.org/10.1093/gbe/evz133</a>.","short":"M.A.L. Picard, B. Vicoso, D. Roquis, I. Bulla, R.C. Augusto, N. Arancibia, C. Grunau, J. Boissier, C. Cosseau, Genome Biology and Evolution 11 (2019) 1909–1922.","ista":"Picard MAL, Vicoso B, Roquis D, Bulla I, Augusto RC, Arancibia N, Grunau C, Boissier J, Cosseau C. 2019. Dosage compensation throughout the Schistosoma mansoni lifecycle: Specific chromatin landscape of the Z chromosome. Genome biology and evolution. 11(7), 1909–1922.","ieee":"M. A. L. Picard <i>et al.</i>, “Dosage compensation throughout the Schistosoma mansoni lifecycle: Specific chromatin landscape of the Z chromosome,” <i>Genome biology and evolution</i>, vol. 11, no. 7. Oxford Academic Press, pp. 1909–1922, 2019.","ama":"Picard MAL, Vicoso B, Roquis D, et al. Dosage compensation throughout the Schistosoma mansoni lifecycle: Specific chromatin landscape of the Z chromosome. <i>Genome biology and evolution</i>. 2019;11(7):1909-1922. doi:<a href=\"https://doi.org/10.1093/gbe/evz133\">10.1093/gbe/evz133</a>"},"quality_controlled":"1","author":[{"orcid":"0000-0002-8101-2518","full_name":"Picard, Marion A L","id":"2C921A7A-F248-11E8-B48F-1D18A9856A87","first_name":"Marion A L","last_name":"Picard"},{"orcid":"0000-0002-4579-8306","full_name":"Vicoso, Beatriz","id":"49E1C5C6-F248-11E8-B48F-1D18A9856A87","first_name":"Beatriz","last_name":"Vicoso"},{"full_name":"Roquis, David","last_name":"Roquis","first_name":"David"},{"last_name":"Bulla","first_name":"Ingo","full_name":"Bulla, Ingo"},{"full_name":"Augusto, Ronaldo C.","first_name":"Ronaldo C.","last_name":"Augusto"},{"full_name":"Arancibia, Nathalie","first_name":"Nathalie","last_name":"Arancibia"},{"first_name":"Christoph","last_name":"Grunau","full_name":"Grunau, Christoph"},{"full_name":"Boissier, Jérôme","first_name":"Jérôme","last_name":"Boissier"},{"last_name":"Cosseau","first_name":"Céline","full_name":"Cosseau, Céline"}],"tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"year":"2019","pmid":1,"title":"Dosage compensation throughout the Schistosoma mansoni lifecycle: Specific chromatin landscape of the Z chromosome","publication":"Genome biology and evolution","_id":"6755","oa":1,"ddc":["570"],"abstract":[{"lang":"eng","text":"Differentiated sex chromosomes are accompanied by a difference in gene dose between X/Z-specific and autosomal genes. At the transcriptomic level, these sex-linked genes can lead to expression imbalance, or gene dosage can be compensated by epigenetic mechanisms and results into expression level equalization. Schistosoma mansoni has been previously described as a ZW species (i.e., female heterogamety, in opposition to XY male heterogametic species) with a partial dosage compensation, but underlying mechanisms are still unexplored. Here, we combine transcriptomic (RNA-Seq) and epigenetic data (ChIP-Seq against H3K4me3, H3K27me3,andH4K20me1histonemarks) in free larval cercariae and intravertebrate parasitic stages. For the first time, we describe differences in dosage compensation status in ZW females, depending on the parasitic status: free cercariae display global dosage compensation, whereas intravertebrate stages show a partial dosage compensation. We also highlight regional differences of gene expression along the Z chromosome in cercariae, but not in the intravertebrate stages. Finally, we feature a consistent permissive chromatin landscape of the Z chromosome in both sexes and stages. We argue that dosage compensation in schistosomes is characterized by chromatin remodeling mechanisms in the Z-specific region."}],"publication_status":"published"},{"intvolume":"        19","isi":1,"date_created":"2019-08-18T22:00:41Z","month":"11","status":"public","volume":19,"issue":"6","article_type":"original","publisher":"Wiley","publication":"Molecular Ecology Resources","title":"Diurnal variation in opsin expression and common housekeeping genes necessitates comprehensive normalization methods for quantitative real-time PCR analyses","pmid":1,"oa":1,"_id":"6821","publication_status":"published","abstract":[{"text":"To determine the visual sensitivities of an organism of interest, quantitative reverse transcription–polymerase chain reaction (qRT–PCR) is often used to quantify expression of the light‐sensitive opsins in the retina. While qRT–PCR is an affordable, high‐throughput method for measuring expression, it comes with inherent normalization issues that affect the interpretation of results, especially as opsin expression can vary greatly based on developmental stage, light environment or diurnal cycles. We tested for diurnal cycles of opsin expression over a period of 24 hr at 1‐hr increments and examined how normalization affects a data set with fluctuating expression levels using qRT–PCR and transcriptome data from the retinae of the cichlid Pelmatolapia mariae. We compared five methods of normalizing opsin expression relative to (a) the average of three stably expressed housekeeping genes (Ube2z, EF1‐α and β‐actin), (b) total RNA concentration, (c) GNAT2, (the cone‐specific subunit of transducin), (d) total opsin expression and (e) only opsins expressed in the same cone type. Normalizing by proportion of cone type produced the least variation and would be best for removing time‐of‐day variation. In contrast, normalizing by housekeeping genes produced the highest daily variation in expression and demonstrated that the peak of cone opsin expression was in the late afternoon. A weighted correlation network analysis showed that the expression of different cone opsins follows a very similar daily cycle. With the knowledge of how these normalization methods affect opsin expression data, we make recommendations for designing sampling approaches and quantification methods based upon the scientific question being examined.","lang":"eng"}],"main_file_link":[{"open_access":"1","url":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995727"}],"citation":{"chicago":"Yourick, Miranda R., Benjamin A. Sandkam, William J Gammerdinger, Daniel Escobar-Camacho, Sri Pratima Nandamuri, Frances E. Clark, Brendan Joyce, Matthew A. Conte, Thomas D. Kocher, and Karen L. Carleton. “Diurnal Variation in Opsin Expression and Common Housekeeping Genes Necessitates Comprehensive Normalization Methods for Quantitative Real-Time PCR Analyses.” <i>Molecular Ecology Resources</i>. Wiley, 2019. <a href=\"https://doi.org/10.1111/1755-0998.13062\">https://doi.org/10.1111/1755-0998.13062</a>.","short":"M.R. Yourick, B.A. Sandkam, W.J. Gammerdinger, D. Escobar-Camacho, S.P. Nandamuri, F.E. Clark, B. Joyce, M.A. Conte, T.D. Kocher, K.L. Carleton, Molecular Ecology Resources 19 (2019) 1447–1460.","ista":"Yourick MR, Sandkam BA, Gammerdinger WJ, Escobar-Camacho D, Nandamuri SP, Clark FE, Joyce B, Conte MA, Kocher TD, Carleton KL. 2019. Diurnal variation in opsin expression and common housekeeping genes necessitates comprehensive normalization methods for quantitative real-time PCR analyses. Molecular Ecology Resources. 19(6), 1447–1460.","ieee":"M. R. Yourick <i>et al.</i>, “Diurnal variation in opsin expression and common housekeeping genes necessitates comprehensive normalization methods for quantitative real-time PCR analyses,” <i>Molecular Ecology Resources</i>, vol. 19, no. 6. Wiley, pp. 1447–1460, 2019.","ama":"Yourick MR, Sandkam BA, Gammerdinger WJ, et al. Diurnal variation in opsin expression and common housekeeping genes necessitates comprehensive normalization methods for quantitative real-time PCR analyses. <i>Molecular Ecology Resources</i>. 2019;19(6):1447-1460. doi:<a href=\"https://doi.org/10.1111/1755-0998.13062\">10.1111/1755-0998.13062</a>","mla":"Yourick, Miranda R., et al. “Diurnal Variation in Opsin Expression and Common Housekeeping Genes Necessitates Comprehensive Normalization Methods for Quantitative Real-Time PCR Analyses.” <i>Molecular Ecology Resources</i>, vol. 19, no. 6, Wiley, 2019, pp. 1447–60, doi:<a href=\"https://doi.org/10.1111/1755-0998.13062\">10.1111/1755-0998.13062</a>.","apa":"Yourick, M. R., Sandkam, B. A., Gammerdinger, W. J., Escobar-Camacho, D., Nandamuri, S. P., Clark, F. E., … Carleton, K. L. (2019). Diurnal variation in opsin expression and common housekeeping genes necessitates comprehensive normalization methods for quantitative real-time PCR analyses. <i>Molecular Ecology Resources</i>. Wiley. <a href=\"https://doi.org/10.1111/1755-0998.13062\">https://doi.org/10.1111/1755-0998.13062</a>"},"author":[{"last_name":"Yourick","first_name":"Miranda R.","full_name":"Yourick, Miranda R."},{"full_name":"Sandkam, Benjamin A.","first_name":"Benjamin A.","last_name":"Sandkam"},{"orcid":"0000-0001-9638-1220","full_name":"Gammerdinger, William J","id":"3A7E01BC-F248-11E8-B48F-1D18A9856A87","last_name":"Gammerdinger","first_name":"William J"},{"full_name":"Escobar-Camacho, Daniel","first_name":"Daniel","last_name":"Escobar-Camacho"},{"last_name":"Nandamuri","first_name":"Sri Pratima","full_name":"Nandamuri, Sri Pratima"},{"last_name":"Clark","first_name":"Frances E.","full_name":"Clark, Frances E."},{"first_name":"Brendan","last_name":"Joyce","full_name":"Joyce, Brendan"},{"first_name":"Matthew A.","last_name":"Conte","full_name":"Conte, Matthew A."},{"first_name":"Thomas D.","last_name":"Kocher","full_name":"Kocher, Thomas D."},{"full_name":"Carleton, Karen L.","first_name":"Karen L.","last_name":"Carleton"}],"quality_controlled":"1","year":"2019","publication_identifier":{"eissn":["1755-0998"]},"scopus_import":"1","date_published":"2019-11-01T00:00:00Z","external_id":{"pmid":["31325910"],"isi":["000480196800001"]},"page":"1447-1460","language":[{"iso":"eng"}],"doi":"10.1111/1755-0998.13062","department":[{"_id":"BeVi"}],"article_processing_charge":"No","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","type":"journal_article","date_updated":"2023-08-29T07:10:44Z","oa_version":"Submitted Version","day":"01"},{"citation":{"ista":"Puixeu Sala G, Pickup M, Field D, Barrett SCH. 2019. Variation in sexual dimorphism in a wind-pollinated plant: The influence of geographical context and life-cycle dynamics. New Phytologist. 224(3), 1108–1120.","chicago":"Puixeu Sala, Gemma, Melinda Pickup, David Field, and Spencer C.H. Barrett. “Variation in Sexual Dimorphism in a Wind-Pollinated Plant: The Influence of Geographical Context and Life-Cycle Dynamics.” <i>New Phytologist</i>. Wiley, 2019. <a href=\"https://doi.org/10.1111/nph.16050\">https://doi.org/10.1111/nph.16050</a>.","short":"G. Puixeu Sala, M. Pickup, D. Field, S.C.H. Barrett, New Phytologist 224 (2019) 1108–1120.","ieee":"G. Puixeu Sala, M. Pickup, D. Field, and S. C. H. Barrett, “Variation in sexual dimorphism in a wind-pollinated plant: The influence of geographical context and life-cycle dynamics,” <i>New Phytologist</i>, vol. 224, no. 3. Wiley, pp. 1108–1120, 2019.","ama":"Puixeu Sala G, Pickup M, Field D, Barrett SCH. Variation in sexual dimorphism in a wind-pollinated plant: The influence of geographical context and life-cycle dynamics. <i>New Phytologist</i>. 2019;224(3):1108-1120. doi:<a href=\"https://doi.org/10.1111/nph.16050\">10.1111/nph.16050</a>","apa":"Puixeu Sala, G., Pickup, M., Field, D., &#38; Barrett, S. C. H. (2019). Variation in sexual dimorphism in a wind-pollinated plant: The influence of geographical context and life-cycle dynamics. <i>New Phytologist</i>. Wiley. <a href=\"https://doi.org/10.1111/nph.16050\">https://doi.org/10.1111/nph.16050</a>","mla":"Puixeu Sala, Gemma, et al. “Variation in Sexual Dimorphism in a Wind-Pollinated Plant: The Influence of Geographical Context and Life-Cycle Dynamics.” <i>New Phytologist</i>, vol. 224, no. 3, Wiley, 2019, pp. 1108–20, doi:<a href=\"https://doi.org/10.1111/nph.16050\">10.1111/nph.16050</a>."},"author":[{"first_name":"Gemma","last_name":"Puixeu Sala","orcid":"0000-0001-8330-1754","full_name":"Puixeu Sala, Gemma","id":"33AB266C-F248-11E8-B48F-1D18A9856A87"},{"orcid":"0000-0001-6118-0541","full_name":"Pickup, Melinda","id":"2C78037E-F248-11E8-B48F-1D18A9856A87","first_name":"Melinda","last_name":"Pickup"},{"last_name":"Field","first_name":"David","orcid":"0000-0002-4014-8478","full_name":"Field, David"},{"last_name":"Barrett","first_name":"Spencer C.H.","full_name":"Barrett, Spencer C.H."}],"quality_controlled":"1","tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"year":"2019","publication":"New Phytologist","title":"Variation in sexual dimorphism in a wind-pollinated plant: The influence of geographical context and life-cycle dynamics","_id":"6831","ddc":["570"],"oa":1,"related_material":{"record":[{"relation":"research_data","status":"public","id":"9803"},{"relation":"dissertation_contains","status":"public","id":"14058"}]},"project":[{"_id":"2564DBCA-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","grant_number":"665385","name":"International IST Doctoral Program"}],"abstract":[{"text":"* Understanding the mechanisms causing phenotypic differences between females and males has long fascinated evolutionary biologists. An extensive literature exists on animal sexual dimorphism but less information is known about sex differences in plants, particularly the extent of geographical variation in sexual dimorphism and its life‐cycle dynamics.\r\n* Here, we investigated patterns of genetically based sexual dimorphism in vegetative and reproductive traits of a wind‐pollinated dioecious plant, Rumex hastatulus, across three life‐cycle stages using open‐pollinated families from 30 populations spanning the geographic range and chromosomal variation (XY and XY1Y2) of the species.\r\n* The direction and degree of sexual dimorphism was highly variable among populations and life‐cycle stages. Sex‐specific differences in reproductive function explained a significant amount of temporal change in sexual dimorphism. For several traits, geographical variation in sexual dimorphism was associated with bioclimatic parameters, likely due to the differential responses of the sexes to climate. We found no systematic differences in sexual dimorphism between chromosome races.\r\n* Sex‐specific trait differences in dioecious plants largely result from a balance between sexual and natural selection on resource allocation. Our results indicate that abiotic factors associated with geographical context also play a role in modifying sexual dimorphism during the plant life‐cycle.","lang":"eng"}],"publication_status":"published","volume":224,"issue":"3","file_date_updated":"2020-07-14T12:47:42Z","publisher":"Wiley","article_type":"original","intvolume":"       224","isi":1,"month":"11","date_created":"2019-08-25T22:00:51Z","status":"public","user_id":"4359f0d1-fa6c-11eb-b949-802e58b17ae8","article_processing_charge":"Yes (via OA deal)","oa_version":"Published Version","date_updated":"2023-08-29T07:17:07Z","type":"journal_article","day":"01","ec_funded":1,"has_accepted_license":"1","department":[{"_id":"NiBa"},{"_id":"BeVi"}],"doi":"10.1111/nph.16050","language":[{"iso":"eng"}],"external_id":{"isi":["000481376500001"]},"file":[{"content_type":"application/pdf","creator":"apreinsp","file_size":2314016,"relation":"main_file","date_created":"2019-08-27T12:44:54Z","checksum":"6370e7567d96b7b562e77d8b89653f80","file_name":"2019_NewPhytologist_Puixeu.pdf","access_level":"open_access","file_id":"6833","date_updated":"2020-07-14T12:47:42Z"}],"date_published":"2019-11-01T00:00:00Z","page":"1108-1120","scopus_import":"1","publication_identifier":{"eissn":["1469-8137"]}},{"abstract":[{"lang":"eng","text":"Understanding the mechanisms causing phenotypic differences between females and males has long fascinated evolutionary biologists. An extensive literature exists on animal sexual dimorphism but less is known about sex differences in plants, particularly the extent of geographical variation in sexual dimorphism and its life-cycle dynamics. Here, we investigate patterns of genetically-based sexual dimorphism in vegetative and reproductive traits of a wind-pollinated dioecious plant, Rumex hastatulus, across three life-cycle stages using open-pollinated families from 30 populations spanning the geographic range and chromosomal variation (XY and XY1Y2) of the species. The direction and degree of sexual dimorphism was highly variable among populations and life-cycle stages. Sex-specific differences in reproductive function explained a significant amount of temporal change in sexual dimorphism. For several traits, geographical variation in sexual dimorphism was associated with bioclimatic parameters, likely due to the differential responses of the sexes to climate. We found no systematic differences in sexual dimorphism between chromosome races. Sex-specific trait differences in dioecious plants largely result from a balance between sexual and natural selection on resource allocation. Our results indicate that abiotic factors associated with geographical context also play a role in modifying sexual dimorphism during the plant life cycle."}],"title":"Data from: Variation in sexual dimorphism in a wind-pollinated plant: the influence of geographical context and life-cycle dynamics","oa":1,"related_material":{"record":[{"id":"14058","relation":"used_in_publication","status":"public"},{"id":"6831","relation":"used_in_publication","status":"public"}]},"doi":"10.5061/dryad.n1701c9","department":[{"_id":"NiBa"},{"_id":"BeVi"}],"_id":"9803","type":"research_data_reference","date_updated":"2023-08-29T07:17:07Z","oa_version":"Published Version","day":"22","year":"2019","main_file_link":[{"url":"https://doi.org/10.5061/dryad.n1701c9","open_access":"1"}],"citation":{"ama":"Puixeu Sala G, Pickup M, Field D, Barrett SCH. Data from: Variation in sexual dimorphism in a wind-pollinated plant: the influence of geographical context and life-cycle dynamics. 2019. doi:<a href=\"https://doi.org/10.5061/dryad.n1701c9\">10.5061/dryad.n1701c9</a>","ieee":"G. Puixeu Sala, M. Pickup, D. Field, and S. C. H. Barrett, “Data from: Variation in sexual dimorphism in a wind-pollinated plant: the influence of geographical context and life-cycle dynamics.” Dryad, 2019.","ista":"Puixeu Sala G, Pickup M, Field D, Barrett SCH. 2019. Data from: Variation in sexual dimorphism in a wind-pollinated plant: the influence of geographical context and life-cycle dynamics, Dryad, <a href=\"https://doi.org/10.5061/dryad.n1701c9\">10.5061/dryad.n1701c9</a>.","chicago":"Puixeu Sala, Gemma, Melinda Pickup, David Field, and Spencer C.H. Barrett. “Data from: Variation in Sexual Dimorphism in a Wind-Pollinated Plant: The Influence of Geographical Context and Life-Cycle Dynamics.” Dryad, 2019. <a href=\"https://doi.org/10.5061/dryad.n1701c9\">https://doi.org/10.5061/dryad.n1701c9</a>.","short":"G. Puixeu Sala, M. Pickup, D. Field, S.C.H. Barrett, (2019).","apa":"Puixeu Sala, G., Pickup, M., Field, D., &#38; Barrett, S. C. H. (2019). Data from: Variation in sexual dimorphism in a wind-pollinated plant: the influence of geographical context and life-cycle dynamics. Dryad. <a href=\"https://doi.org/10.5061/dryad.n1701c9\">https://doi.org/10.5061/dryad.n1701c9</a>","mla":"Puixeu Sala, Gemma, et al. <i>Data from: Variation in Sexual Dimorphism in a Wind-Pollinated Plant: The Influence of Geographical Context and Life-Cycle Dynamics</i>. Dryad, 2019, doi:<a href=\"https://doi.org/10.5061/dryad.n1701c9\">10.5061/dryad.n1701c9</a>."},"article_processing_charge":"No","author":[{"first_name":"Gemma","last_name":"Puixeu Sala","id":"33AB266C-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-8330-1754","full_name":"Puixeu Sala, Gemma"},{"first_name":"Melinda","last_name":"Pickup","full_name":"Pickup, Melinda","orcid":"0000-0001-6118-0541","id":"2C78037E-F248-11E8-B48F-1D18A9856A87"},{"full_name":"Field, David","last_name":"Field","first_name":"David"},{"full_name":"Barrett, Spencer C.H.","first_name":"Spencer C.H.","last_name":"Barrett"}],"user_id":"6785fbc1-c503-11eb-8a32-93094b40e1cf","date_created":"2021-08-06T11:48:42Z","month":"07","status":"public","publisher":"Dryad","date_published":"2019-07-22T00:00:00Z"},{"citation":{"mla":"Picard, Marion A. L., et al. “Evolution of Gene Dosage on the Z-Chromosome of Schistosome Parasites.” <i>ELife</i>, vol. 7, e35684, eLife Sciences Publications, 2018, doi:<a href=\"https://doi.org/10.7554/eLife.35684\">10.7554/eLife.35684</a>.","apa":"Picard, M. A. L., Cosseau, C., Ferré, S., Quack, T., Grevelding, C., Couté, Y., &#38; Vicoso, B. (2018). Evolution of gene dosage on the Z-chromosome of schistosome parasites. <i>ELife</i>. eLife Sciences Publications. <a href=\"https://doi.org/10.7554/eLife.35684\">https://doi.org/10.7554/eLife.35684</a>","ama":"Picard MAL, Cosseau C, Ferré S, et al. Evolution of gene dosage on the Z-chromosome of schistosome parasites. <i>eLife</i>. 2018;7. doi:<a href=\"https://doi.org/10.7554/eLife.35684\">10.7554/eLife.35684</a>","ieee":"M. A. L. Picard <i>et al.</i>, “Evolution of gene dosage on the Z-chromosome of schistosome parasites,” <i>eLife</i>, vol. 7. eLife Sciences Publications, 2018.","ista":"Picard MAL, Cosseau C, Ferré S, Quack T, Grevelding C, Couté Y, Vicoso B. 2018. Evolution of gene dosage on the Z-chromosome of schistosome parasites. eLife. 7, e35684.","short":"M.A.L. Picard, C. Cosseau, S. Ferré, T. Quack, C. Grevelding, Y. Couté, B. Vicoso, ELife 7 (2018).","chicago":"Picard, Marion A L, Celine Cosseau, Sabrina Ferré, Thomas Quack, Christoph Grevelding, Yohann Couté, and Beatriz Vicoso. “Evolution of Gene Dosage on the Z-Chromosome of Schistosome Parasites.” <i>ELife</i>. eLife Sciences Publications, 2018. <a href=\"https://doi.org/10.7554/eLife.35684\">https://doi.org/10.7554/eLife.35684</a>."},"quality_controlled":"1","author":[{"orcid":"0000-0002-8101-2518","full_name":"Picard, Marion A","id":"2C921A7A-F248-11E8-B48F-1D18A9856A87","first_name":"Marion A","last_name":"Picard"},{"full_name":"Cosseau, Celine","first_name":"Celine","last_name":"Cosseau"},{"last_name":"Ferré","first_name":"Sabrina","full_name":"Ferré, Sabrina"},{"full_name":"Quack, Thomas","first_name":"Thomas","last_name":"Quack"},{"last_name":"Grevelding","first_name":"Christoph","full_name":"Grevelding, Christoph"},{"full_name":"Couté, Yohann","last_name":"Couté","first_name":"Yohann"},{"last_name":"Vicoso","first_name":"Beatriz","id":"49E1C5C6-F248-11E8-B48F-1D18A9856A87","full_name":"Vicoso, Beatriz","orcid":"0000-0002-4579-8306"}],"tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"year":"2018","title":"Evolution of gene dosage on the Z-chromosome of schistosome parasites","publication":"eLife","related_material":{"record":[{"status":"public","relation":"popular_science","id":"5586"}]},"ddc":["570"],"oa":1,"_id":"131","project":[{"_id":"250ED89C-B435-11E9-9278-68D0E5697425","call_identifier":"FWF","name":"Sex chromosome evolution under male- and female- heterogamety","grant_number":"P28842-B22"}],"publication_status":"published","abstract":[{"text":"XY systems usually show chromosome-wide compensation of X-linked genes, while in many ZW systems, compensation is restricted to a minority of dosage-sensitive genes. Why such differences arose is still unclear. Here, we combine comparative genomics, transcriptomics and proteomics to obtain a complete overview of the evolution of gene dosage on the Z-chromosome of Schistosoma parasites. We compare the Z-chromosome gene content of African (Schistosoma mansoni and S. haematobium) and Asian (S. japonicum) schistosomes and describe lineage-specific evolutionary strata. We use these to assess gene expression evolution following sex-linkage. The resulting patterns suggest a reduction in expression of Z-linked genes in females, combined with upregulation of the Z in both sexes, in line with the first step of Ohno’s classic model of dosage compensation evolution. Quantitative proteomics suggest that post-transcriptional mechanisms do not play a major role in balancing the expression of Z-linked genes. ","lang":"eng"}],"volume":7,"file_date_updated":"2020-07-14T12:44:43Z","article_type":"original","publisher":"eLife Sciences Publications","intvolume":"         7","publist_id":"7792","isi":1,"date_created":"2018-12-11T11:44:47Z","month":"08","article_number":"e35684","status":"public","article_processing_charge":"No","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","type":"journal_article","date_updated":"2024-02-21T13:45:12Z","oa_version":"Published Version","day":"13","doi":"10.7554/eLife.35684","language":[{"iso":"eng"}],"department":[{"_id":"BeVi"}],"has_accepted_license":"1","acknowledgement":"We are grateful to Lu Dabing (Soochow University, Suzhou, China) for providing Schistosoma japonicum samples, to Ariana Macon (IST Austria) and Georgette Stovall (JLU Giessen) for technical assistance, to IT support at IST Austria for providing optimal environment to bioinformatic analyses, and to the Vicoso lab for comments on the manuscript.","date_published":"2018-08-13T00:00:00Z","external_id":{"isi":["000441388200001"]},"file":[{"content_type":"application/pdf","creator":"dernst","file_size":3158125,"relation":"main_file","date_created":"2018-12-17T11:55:05Z","checksum":"d6331d4385b1fffd6b47b45d5949d841","file_name":"2018_eLife_Picard.pdf","access_level":"open_access","date_updated":"2020-07-14T12:44:43Z","file_id":"5695"}],"scopus_import":"1"},{"volume":330,"article_type":"original","publisher":"Wiley","isi":1,"publist_id":"7730","intvolume":"       330","status":"public","month":"07","date_created":"2018-12-11T11:45:06Z","author":[{"full_name":"Harrison, Mark","last_name":"Harrison","first_name":"Mark"},{"first_name":"Nicolas","last_name":"Arning","full_name":"Arning, Nicolas"},{"full_name":"Kremer, Lucas","last_name":"Kremer","first_name":"Lucas"},{"full_name":"Ylla, Guillem","last_name":"Ylla","first_name":"Guillem"},{"full_name":"Belles, Xavier","first_name":"Xavier","last_name":"Belles"},{"first_name":"Erich","last_name":"Bornberg Bauer","full_name":"Bornberg Bauer, Erich"},{"full_name":"Huylmans, Ann K","orcid":"0000-0001-8871-4961","id":"4C0A3874-F248-11E8-B48F-1D18A9856A87","first_name":"Ann K","last_name":"Huylmans"},{"first_name":"Evelien","last_name":"Jongepier","full_name":"Jongepier, Evelien"},{"last_name":"Puilachs","first_name":"Maria","full_name":"Puilachs, Maria"},{"full_name":"Richards, Stephen","last_name":"Richards","first_name":"Stephen"},{"full_name":"Schal, Coby","first_name":"Coby","last_name":"Schal"}],"quality_controlled":"1","citation":{"ama":"Harrison M, Arning N, Kremer L, et al. Expansions of key protein families in the German cockroach highlight the molecular basis of its remarkable success as a global indoor pest. <i>Journal of Experimental Zoology Part B: Molecular and Developmental Evolution</i>. 2018;330:254-264. doi:<a href=\"https://doi.org/10.1002/jez.b.22824\">10.1002/jez.b.22824</a>","ieee":"M. Harrison <i>et al.</i>, “Expansions of key protein families in the German cockroach highlight the molecular basis of its remarkable success as a global indoor pest,” <i>Journal of Experimental Zoology Part B: Molecular and Developmental Evolution</i>, vol. 330. Wiley, pp. 254–264, 2018.","ista":"Harrison M, Arning N, Kremer L, Ylla G, Belles X, Bornberg Bauer E, Huylmans AK, Jongepier E, Puilachs M, Richards S, Schal C. 2018. Expansions of key protein families in the German cockroach highlight the molecular basis of its remarkable success as a global indoor pest. Journal of Experimental Zoology Part B: Molecular and Developmental Evolution. 330, 254–264.","short":"M. Harrison, N. Arning, L. Kremer, G. Ylla, X. Belles, E. Bornberg Bauer, A.K. Huylmans, E. Jongepier, M. Puilachs, S. Richards, C. Schal, Journal of Experimental Zoology Part B: Molecular and Developmental Evolution 330 (2018) 254–264.","chicago":"Harrison, Mark, Nicolas Arning, Lucas Kremer, Guillem Ylla, Xavier Belles, Erich Bornberg Bauer, Ann K Huylmans, et al. “Expansions of Key Protein Families in the German Cockroach Highlight the Molecular Basis of Its Remarkable Success as a Global Indoor Pest.” <i>Journal of Experimental Zoology Part B: Molecular and Developmental Evolution</i>. Wiley, 2018. <a href=\"https://doi.org/10.1002/jez.b.22824\">https://doi.org/10.1002/jez.b.22824</a>.","apa":"Harrison, M., Arning, N., Kremer, L., Ylla, G., Belles, X., Bornberg Bauer, E., … Schal, C. (2018). Expansions of key protein families in the German cockroach highlight the molecular basis of its remarkable success as a global indoor pest. <i>Journal of Experimental Zoology Part B: Molecular and Developmental Evolution</i>. Wiley. <a href=\"https://doi.org/10.1002/jez.b.22824\">https://doi.org/10.1002/jez.b.22824</a>","mla":"Harrison, Mark, et al. “Expansions of Key Protein Families in the German Cockroach Highlight the Molecular Basis of Its Remarkable Success as a Global Indoor Pest.” <i>Journal of Experimental Zoology Part B: Molecular and Developmental Evolution</i>, vol. 330, Wiley, 2018, pp. 254–64, doi:<a href=\"https://doi.org/10.1002/jez.b.22824\">10.1002/jez.b.22824</a>."},"main_file_link":[{"open_access":"1","url":"https://onlinelibrary.wiley.com/doi/am-pdf/10.1002/jez.b.22824"}],"year":"2018","_id":"190","oa":1,"pmid":1,"publication":"Journal of Experimental Zoology Part B: Molecular and Developmental Evolution","title":"Expansions of key protein families in the German cockroach highlight the molecular basis of its remarkable success as a global indoor pest","abstract":[{"text":"The German cockroach, Blattella germanica, is a worldwide pest that infests buildings, including homes, restaurants, and hospitals, often living in unsanitary conditions. As a disease vector and producer of allergens, this species has major health and economic impacts on humans. Factors contributing to the success of the German cockroach include its resistance to a broad range of insecticides, immunity to many pathogens, and its ability, as an extreme generalist omnivore, to survive on most food sources. The recently published genome shows that B. germanica has an exceptionally high number of protein coding genes. In this study, we investigate the functions of the 93 significantly expanded gene families with the aim to better understand the success of B. germanica as a major pest despite such inhospitable conditions. We find major expansions in gene families with functions related to the detoxification of insecticides and allelochemicals, defense against pathogens, digestion, sensory perception, and gene regulation. These expansions might have allowed B. germanica to develop multiple resistance mechanisms to insecticides and pathogens, and enabled a broad, flexible diet, thus explaining its success in unsanitary conditions and under recurrent chemical control. The findings and resources presented here provide insights for better understanding molecular mechanisms that will facilitate more effective cockroach control.","lang":"eng"}],"publication_status":"published","page":"254-264","external_id":{"pmid":["29998472"],"isi":["000443231000002"]},"date_published":"2018-07-11T00:00:00Z","scopus_import":"1","article_processing_charge":"No","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","day":"11","oa_version":"Submitted Version","type":"journal_article","date_updated":"2023-09-11T13:59:54Z","department":[{"_id":"BeVi"}],"doi":"10.1002/jez.b.22824","language":[{"iso":"eng"}]},{"issue":"6","volume":9,"file_date_updated":"2020-07-14T12:45:22Z","publisher":"MDPI AG","intvolume":"         9","isi":1,"publist_id":"7714","month":"06","date_created":"2018-12-11T11:45:09Z","status":"public","article_number":"294","citation":{"apa":"Ma, W., Veltsos, P., Toups, M. A., Rodrigues, N., Sermier, R., Jeffries, D., &#38; Perrin, N. (2018). Tissue specificity and dynamics of sex biased gene expression in a common frog population with differentiated, yet homomorphic, sex chromosomes. <i>Genes</i>. MDPI AG. <a href=\"https://doi.org/10.3390/genes9060294\">https://doi.org/10.3390/genes9060294</a>","mla":"Ma, Wen, et al. “Tissue Specificity and Dynamics of Sex Biased Gene Expression in a Common Frog Population with Differentiated, yet Homomorphic, Sex Chromosomes.” <i>Genes</i>, vol. 9, no. 6, 294, MDPI AG, 2018, doi:<a href=\"https://doi.org/10.3390/genes9060294\">10.3390/genes9060294</a>.","ama":"Ma W, Veltsos P, Toups MA, et al. Tissue specificity and dynamics of sex biased gene expression in a common frog population with differentiated, yet homomorphic, sex chromosomes. <i>Genes</i>. 2018;9(6). doi:<a href=\"https://doi.org/10.3390/genes9060294\">10.3390/genes9060294</a>","ieee":"W. Ma <i>et al.</i>, “Tissue specificity and dynamics of sex biased gene expression in a common frog population with differentiated, yet homomorphic, sex chromosomes,” <i>Genes</i>, vol. 9, no. 6. MDPI AG, 2018.","short":"W. Ma, P. Veltsos, M.A. Toups, N. Rodrigues, R. Sermier, D. Jeffries, N. Perrin, Genes 9 (2018).","chicago":"Ma, Wen, Paris Veltsos, Melissa A Toups, Nicolas Rodrigues, Roberto Sermier, Daniel Jeffries, and Nicolas Perrin. “Tissue Specificity and Dynamics of Sex Biased Gene Expression in a Common Frog Population with Differentiated, yet Homomorphic, Sex Chromosomes.” <i>Genes</i>. MDPI AG, 2018. <a href=\"https://doi.org/10.3390/genes9060294\">https://doi.org/10.3390/genes9060294</a>.","ista":"Ma W, Veltsos P, Toups MA, Rodrigues N, Sermier R, Jeffries D, Perrin N. 2018. Tissue specificity and dynamics of sex biased gene expression in a common frog population with differentiated, yet homomorphic, sex chromosomes. Genes. 9(6), 294."},"author":[{"first_name":"Wen","last_name":"Ma","full_name":"Ma, Wen"},{"first_name":"Paris","last_name":"Veltsos","full_name":"Veltsos, Paris"},{"id":"4E099E4E-F248-11E8-B48F-1D18A9856A87","full_name":"Toups, Melissa A","orcid":"0000-0002-9752-7380","last_name":"Toups","first_name":"Melissa A"},{"full_name":"Rodrigues, Nicolas","last_name":"Rodrigues","first_name":"Nicolas"},{"full_name":"Sermier, Roberto","last_name":"Sermier","first_name":"Roberto"},{"full_name":"Jeffries, Daniel","last_name":"Jeffries","first_name":"Daniel"},{"full_name":"Perrin, Nicolas","first_name":"Nicolas","last_name":"Perrin"}],"quality_controlled":"1","tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"year":"2018","title":"Tissue specificity and dynamics of sex biased gene expression in a common frog population with differentiated, yet homomorphic, sex chromosomes","publication":"Genes","_id":"199","oa":1,"ddc":["570"],"abstract":[{"lang":"eng","text":"Sex-biased genes are central to the study of sexual selection, sexual antagonism, and sex chromosome evolution. We describe a comprehensive de novo assembled transcriptome in the common frog Rana temporaria based on five developmental stages and three adult tissues from both sexes, obtained from a population with karyotypically homomorphic but genetically differentiated sex chromosomes. This allows the study of sex-biased gene expression throughout development, and its effect on the rate of gene evolution while accounting for pleiotropic expression, which is known to negatively correlate with the evolutionary rate. Overall, sex-biased genes had little overlap among developmental stages and adult tissues. Late developmental stages and gonad tissues had the highest numbers of stage-or tissue-specific genes. We find that pleiotropic gene expression is a better predictor than sex bias for the evolutionary rate of genes, though it often interacts with sex bias. Although genetically differentiated, the sex chromosomes were not enriched in sex-biased genes, possibly due to a very recent arrest of XY recombination. These results extend our understanding of the developmental dynamics, tissue specificity, and genomic localization of sex-biased genes."}],"publication_status":"published","file":[{"access_level":"open_access","file_name":"2018_Genes_Ma.pdf","checksum":"423069beb1cd3cdd25bf3f464b38f1d7","file_id":"5905","date_updated":"2020-07-14T12:45:22Z","file_size":3985796,"creator":"dernst","content_type":"application/pdf","date_created":"2019-02-01T07:52:28Z","relation":"main_file"}],"external_id":{"isi":["000436494200026"]},"date_published":"2018-06-12T00:00:00Z","scopus_import":"1","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","article_processing_charge":"No","oa_version":"Published Version","date_updated":"2023-09-19T10:15:31Z","type":"journal_article","day":"12","has_accepted_license":"1","department":[{"_id":"BeVi"}],"doi":"10.3390/genes9060294","language":[{"iso":"eng"}]},{"date_updated":"2023-10-17T12:25:28Z","type":"journal_article","oa_version":"Published Version","day":"30","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_processing_charge":"No","language":[{"iso":"eng"}],"doi":"10.7717/peerj.5198","has_accepted_license":"1","department":[{"_id":"BeVi"},{"_id":"NiBa"}],"date_published":"2018-07-30T00:00:00Z","external_id":{"isi":["000440484800002"]},"file":[{"date_updated":"2020-07-14T12:44:48Z","file_id":"5739","access_level":"open_access","checksum":"7d55ae22598a1c70759cd671600cff53","file_name":"2018_PeerJ_Fraisse.pdf","date_created":"2018-12-18T09:42:11Z","relation":"main_file","creator":"dernst","content_type":"application/pdf","file_size":1480792}],"scopus_import":"1","tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"year":"2018","citation":{"ista":"Fraisse C, Roux C, Gagnaire P, Romiguier J, Faivre N, Welch J, Bierne N. 2018. The divergence history of European blue mussel species reconstructed from Approximate Bayesian Computation: The effects of sequencing techniques and sampling strategies. PeerJ. 2018(7), 30083438.","short":"C. Fraisse, C. Roux, P. Gagnaire, J. Romiguier, N. Faivre, J. Welch, N. Bierne, PeerJ 2018 (2018).","chicago":"Fraisse, Christelle, Camille Roux, Pierre Gagnaire, Jonathan Romiguier, Nicolas Faivre, John Welch, and Nicolas Bierne. “The Divergence History of European Blue Mussel Species Reconstructed from Approximate Bayesian Computation: The Effects of Sequencing Techniques and Sampling Strategies.” <i>PeerJ</i>. PeerJ, 2018. <a href=\"https://doi.org/10.7717/peerj.5198\">https://doi.org/10.7717/peerj.5198</a>.","ieee":"C. Fraisse <i>et al.</i>, “The divergence history of European blue mussel species reconstructed from Approximate Bayesian Computation: The effects of sequencing techniques and sampling strategies,” <i>PeerJ</i>, vol. 2018, no. 7. PeerJ, 2018.","ama":"Fraisse C, Roux C, Gagnaire P, et al. The divergence history of European blue mussel species reconstructed from Approximate Bayesian Computation: The effects of sequencing techniques and sampling strategies. <i>PeerJ</i>. 2018;2018(7). doi:<a href=\"https://doi.org/10.7717/peerj.5198\">10.7717/peerj.5198</a>","apa":"Fraisse, C., Roux, C., Gagnaire, P., Romiguier, J., Faivre, N., Welch, J., &#38; Bierne, N. (2018). The divergence history of European blue mussel species reconstructed from Approximate Bayesian Computation: The effects of sequencing techniques and sampling strategies. <i>PeerJ</i>. PeerJ. <a href=\"https://doi.org/10.7717/peerj.5198\">https://doi.org/10.7717/peerj.5198</a>","mla":"Fraisse, Christelle, et al. “The Divergence History of European Blue Mussel Species Reconstructed from Approximate Bayesian Computation: The Effects of Sequencing Techniques and Sampling Strategies.” <i>PeerJ</i>, vol. 2018, no. 7, 30083438, PeerJ, 2018, doi:<a href=\"https://doi.org/10.7717/peerj.5198\">10.7717/peerj.5198</a>."},"author":[{"first_name":"Christelle","last_name":"Fraisse","id":"32DF5794-F248-11E8-B48F-1D18A9856A87","full_name":"Fraisse, Christelle","orcid":"0000-0001-8441-5075"},{"full_name":"Roux, Camille","first_name":"Camille","last_name":"Roux"},{"full_name":"Gagnaire, Pierre","last_name":"Gagnaire","first_name":"Pierre"},{"full_name":"Romiguier, Jonathan","first_name":"Jonathan","last_name":"Romiguier"},{"last_name":"Faivre","first_name":"Nicolas","full_name":"Faivre, Nicolas"},{"full_name":"Welch, John","first_name":"John","last_name":"Welch"},{"first_name":"Nicolas","last_name":"Bierne","full_name":"Bierne, Nicolas"}],"quality_controlled":"1","publication_status":"published","abstract":[{"text":"Genome-scale diversity data are increasingly available in a variety of biological systems, and can be used to reconstruct the past evolutionary history of species divergence. However, extracting the full demographic information from these data is not trivial, and requires inferential methods that account for the diversity of coalescent histories throughout the genome. Here, we evaluate the potential and limitations of one such approach. We reexamine a well-known system of mussel sister species, using the joint site frequency spectrum (jSFS) of synonymousmutations computed either fromexome capture or RNA-seq, in an Approximate Bayesian Computation (ABC) framework. We first assess the best sampling strategy (number of: individuals, loci, and bins in the jSFS), and show that model selection is robust to variation in the number of individuals and loci. In contrast, different binning choices when summarizing the jSFS, strongly affect the results: including classes of low and high frequency shared polymorphisms can more effectively reveal recent migration events. We then take advantage of the flexibility of ABC to compare more realistic models of speciation, including variation in migration rates through time (i.e., periodic connectivity) and across genes (i.e., genome-wide heterogeneity in migration rates). We show that these models were consistently selected as the most probable, suggesting that mussels have experienced a complex history of gene flow during divergence and that the species boundary is semi-permeable. Our work provides a comprehensive evaluation of ABC demographic inference in mussels based on the coding jSFS, and supplies guidelines for employing different sequencing techniques and sampling strategies. We emphasize, perhaps surprisingly, that inferences are less limited by the volume of data, than by the way in which they are analyzed.","lang":"eng"}],"publication":"PeerJ","title":"The divergence history of European blue mussel species reconstructed from Approximate Bayesian Computation: The effects of sequencing techniques and sampling strategies","ddc":["576"],"oa":1,"_id":"139","file_date_updated":"2020-07-14T12:44:48Z","publisher":"PeerJ","issue":"7","volume":2018,"date_created":"2018-12-11T11:44:50Z","month":"07","status":"public","article_number":"30083438","intvolume":"      2018","publist_id":"7784","isi":1},{"project":[{"_id":"250BDE62-B435-11E9-9278-68D0E5697425","call_identifier":"H2020","grant_number":"715257","name":"Prevalence and Influence of Sexual Antagonism on Genome Evolution"}],"publication_status":"published","abstract":[{"text":"The t-haplotype, a mouse meiotic driver found on chromosome 17, has been a model for autosomal segregation distortion for close to a century, but several questions remain regarding its biology and evolutionary history. A recently published set of population genomics resources for wild mice includes several individuals heterozygous for the t-haplotype, which we use to characterize this selfish element at the genomic and transcriptomic level. Our results show that large sections of the t-haplotype have been replaced by standard homologous sequences, possibly due to occasional events of recombination, and that this complicates the inference of its history. As expected for a long genomic segment of very low recombination, the t-haplotype carries an excess of fixed nonsynonymous mutations compared to the standard chromosome. This excess is stronger for regions that have not undergone recent recombination, suggesting that occasional gene flow between the t and the standard chromosome may provide a mechanism to regenerate coding sequences that have accumulated deleterious mutations. Finally, we find that t-complex genes with altered expression largely overlap with deleted or amplified regions, and that carrying a t-haplotype alters the testis expression of genes outside of the t-complex, providing new leads into the pathways involved in the biology of this segregation distorter.","lang":"eng"}],"title":"Complex history and differentiation patterns of the t-haplotype, a mouse meiotic driver","publication":"Genetics","ddc":["576"],"oa":1,"related_material":{"record":[{"id":"5571","relation":"popular_science","status":"public"},{"id":"5572","relation":"popular_science","status":"public"}]},"_id":"542","tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"year":"2018","citation":{"ista":"Kelemen RK, Vicoso B. 2018. Complex history and differentiation patterns of the t-haplotype, a mouse meiotic driver. Genetics. 208(1), 365–375.","short":"R.K. Kelemen, B. Vicoso, Genetics 208 (2018) 365–375.","chicago":"Kelemen, Réka K, and Beatriz Vicoso. “Complex History and Differentiation Patterns of the T-Haplotype, a Mouse Meiotic Driver.” <i>Genetics</i>. Genetics Society of America, 2018. <a href=\"https://doi.org/10.1534/genetics.117.300513\">https://doi.org/10.1534/genetics.117.300513</a>.","ieee":"R. K. Kelemen and B. Vicoso, “Complex history and differentiation patterns of the t-haplotype, a mouse meiotic driver,” <i>Genetics</i>, vol. 208, no. 1. Genetics Society of America, pp. 365–375, 2018.","ama":"Kelemen RK, Vicoso B. Complex history and differentiation patterns of the t-haplotype, a mouse meiotic driver. <i>Genetics</i>. 2018;208(1):365-375. doi:<a href=\"https://doi.org/10.1534/genetics.117.300513\">10.1534/genetics.117.300513</a>","apa":"Kelemen, R. K., &#38; Vicoso, B. (2018). Complex history and differentiation patterns of the t-haplotype, a mouse meiotic driver. <i>Genetics</i>. Genetics Society of America. <a href=\"https://doi.org/10.1534/genetics.117.300513\">https://doi.org/10.1534/genetics.117.300513</a>","mla":"Kelemen, Réka K., and Beatriz Vicoso. “Complex History and Differentiation Patterns of the T-Haplotype, a Mouse Meiotic Driver.” <i>Genetics</i>, vol. 208, no. 1, Genetics Society of America, 2018, pp. 365–75, doi:<a href=\"https://doi.org/10.1534/genetics.117.300513\">10.1534/genetics.117.300513</a>."},"author":[{"last_name":"Kelemen","first_name":"Réka K","id":"48D3F8DE-F248-11E8-B48F-1D18A9856A87","full_name":"Kelemen, Réka K","orcid":"0000-0002-8489-9281"},{"orcid":"0000-0002-4579-8306","full_name":"Vicoso, Beatriz","id":"49E1C5C6-F248-11E8-B48F-1D18A9856A87","last_name":"Vicoso","first_name":"Beatriz"}],"quality_controlled":"1","date_created":"2018-12-11T11:47:04Z","month":"01","status":"public","intvolume":"       208","publist_id":"7274","isi":1,"file_date_updated":"2020-07-14T12:46:50Z","publisher":"Genetics Society of America","article_type":"original","volume":208,"issue":"1","pubrep_id":"1058","ec_funded":1,"doi":"10.1534/genetics.117.300513","language":[{"iso":"eng"}],"department":[{"_id":"BeVi"}],"has_accepted_license":"1","type":"journal_article","date_updated":"2024-02-21T13:48:27Z","oa_version":"Published Version","day":"01","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","article_processing_charge":"No","scopus_import":"1","date_published":"2018-01-01T00:00:00Z","file":[{"file_size":1311661,"content_type":"application/pdf","creator":"system","date_created":"2018-12-12T10:15:14Z","relation":"main_file","access_level":"open_access","file_name":"IST-2018-1058-v1+1_365.full__1_.pdf","checksum":"2123845e7031a0cf043905be160f9e69","date_updated":"2020-07-14T12:46:50Z","file_id":"5132"}],"external_id":{"isi":["000419356300024"]},"page":"365 - 375"},{"citation":{"chicago":"Vicoso, Beatriz. “Input Files and Scripts from ‘Evolution of Gene Dosage on the Z-Chromosome of Schistosome Parasites’ by Picard M.A.L., et Al (2018).” Institute of Science and Technology Austria, 2018. <a href=\"https://doi.org/10.15479/AT:ISTA:109\">https://doi.org/10.15479/AT:ISTA:109</a>.","short":"B. Vicoso, (2018).","ista":"Vicoso B. 2018. Input files and scripts from ‘Evolution of gene dosage on the Z-chromosome of schistosome parasites’ by Picard M.A.L., et al (2018), Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/AT:ISTA:109\">10.15479/AT:ISTA:109</a>.","ieee":"B. Vicoso, “Input files and scripts from ‘Evolution of gene dosage on the Z-chromosome of schistosome parasites’ by Picard M.A.L., et al (2018).” Institute of Science and Technology Austria, 2018.","ama":"Vicoso B. Input files and scripts from “Evolution of gene dosage on the Z-chromosome of schistosome parasites” by Picard M.A.L., et al (2018). 2018. doi:<a href=\"https://doi.org/10.15479/AT:ISTA:109\">10.15479/AT:ISTA:109</a>","apa":"Vicoso, B. (2018). Input files and scripts from “Evolution of gene dosage on the Z-chromosome of schistosome parasites” by Picard M.A.L., et al (2018). Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/AT:ISTA:109\">https://doi.org/10.15479/AT:ISTA:109</a>","mla":"Vicoso, Beatriz. <i>Input Files and Scripts from “Evolution of Gene Dosage on the Z-Chromosome of Schistosome Parasites” by Picard M.A.L., et Al (2018)</i>. Institute of Science and Technology Austria, 2018, doi:<a href=\"https://doi.org/10.15479/AT:ISTA:109\">10.15479/AT:ISTA:109</a>."},"author":[{"last_name":"Vicoso","first_name":"Beatriz","orcid":"0000-0002-4579-8306","full_name":"Vicoso, Beatriz","id":"49E1C5C6-F248-11E8-B48F-1D18A9856A87"}],"user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","article_processing_charge":"No","oa_version":"Published Version","tmp":{"short":"CC0 (1.0)","legal_code_url":"https://creativecommons.org/publicdomain/zero/1.0/legalcode","name":"Creative Commons Public Domain Dedication (CC0 1.0)","image":"/images/cc_0.png"},"type":"research_data","date_updated":"2024-02-21T13:45:12Z","year":"2018","contributor":[{"first_name":"Marion A","last_name":"Picard","id":"2C921A7A-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8101-2518"}],"day":"24","title":"Input files and scripts from \"Evolution of gene dosage on the Z-chromosome of schistosome parasites\" by Picard M.A.L., et al (2018)","_id":"5586","department":[{"_id":"BeVi"}],"has_accepted_license":"1","ddc":["570"],"related_material":{"record":[{"id":"131","status":"public","relation":"research_paper"}]},"doi":"10.15479/AT:ISTA:109","oa":1,"project":[{"_id":"250ED89C-B435-11E9-9278-68D0E5697425","call_identifier":"FWF","grant_number":"P28842-B22","name":"Sex chromosome evolution under male- and female- heterogamety"}],"abstract":[{"lang":"eng","text":"Input files and scripts from \"Evolution of gene dosage on the Z-chromosome of schistosome parasites\" by Picard M.A.L., et al (2018)."}],"keyword":["schistosoma","Z-chromosome","gene expression"],"file":[{"file_id":"5601","date_updated":"2020-07-14T12:47:08Z","access_level":"open_access","checksum":"e60b484bd6f55c08eb66a189cb72c923","file_name":"IST-2018-109-v1+1_SupplementaryMethods.zip","date_created":"2018-12-12T13:02:35Z","relation":"main_file","content_type":"application/zip","creator":"system","file_size":11918144}],"date_published":"2018-07-24T00:00:00Z","datarep_id":"109","file_date_updated":"2020-07-14T12:47:08Z","publisher":"Institute of Science and Technology Austria","month":"07","date_created":"2018-12-12T12:31:40Z","status":"public"},{"file_date_updated":"2020-07-14T12:47:11Z","publisher":"Institute of Science and Technology Austria","file":[{"file_name":"FileS1.zip","checksum":"aed7ee9ca3f4dc07d8a66945f68e13cd","access_level":"open_access","date_updated":"2020-07-14T12:47:11Z","file_id":"5758","creator":"cfraisse","content_type":"application/zip","file_size":369837892,"relation":"main_file","date_created":"2018-12-19T14:19:52Z"},{"access_level":"open_access","file_name":"FileS2.zip","checksum":"3592e467b4d8206650860b612d6e12f3","date_updated":"2020-07-14T12:47:11Z","file_id":"5759","file_size":84856909,"creator":"cfraisse","content_type":"application/zip","date_created":"2018-12-19T14:19:49Z","relation":"main_file"},{"file_id":"5760","date_updated":"2020-07-14T12:47:11Z","file_name":"FileS3.txt","checksum":"c37ac5d5437c457338afc128c1240655","access_level":"open_access","relation":"main_file","date_created":"2018-12-19T14:19:49Z","creator":"cfraisse","content_type":"text/plain","file_size":881133},{"access_level":"open_access","file_name":"FileS4.txt","checksum":"943dfd14da61817441e33e3e3cb8cdb9","file_id":"5761","date_updated":"2020-07-14T12:47:11Z","creator":"cfraisse","content_type":"text/plain","file_size":883742,"date_created":"2018-12-19T14:19:49Z","relation":"main_file"},{"checksum":"1c669b6c4690ec1bbca3e2da9f566d17","file_name":"FileS5.txt","access_level":"open_access","file_id":"5762","date_updated":"2020-07-14T12:47:11Z","content_type":"text/plain","creator":"cfraisse","file_size":2495437,"relation":"main_file","date_created":"2018-12-19T14:19:49Z"},{"date_created":"2018-12-19T14:19:50Z","relation":"main_file","file_size":15913457,"creator":"cfraisse","content_type":"text/plain","file_id":"5763","date_updated":"2020-07-14T12:47:11Z","access_level":"open_access","checksum":"f40f661b987ca6fb6b47f650cbbb04e6","file_name":"FileS6.txt"},{"file_size":2584120,"content_type":"text/plain","creator":"cfraisse","date_created":"2018-12-19T14:19:50Z","relation":"main_file","access_level":"open_access","checksum":"25f41e5b8a075669c6c88d4c6713bf6f","file_name":"FileS7.txt","date_updated":"2020-07-14T12:47:11Z","file_id":"5764"},{"relation":"main_file","date_created":"2018-12-19T14:19:50Z","creator":"cfraisse","content_type":"text/plain","file_size":2446059,"file_id":"5765","date_updated":"2020-07-14T12:47:11Z","checksum":"f6c0bd3e63e14ddf5445bd69b43a9152","file_name":"FileS8.txt","access_level":"open_access"},{"content_type":"text/plain","creator":"cfraisse","file_size":100737,"date_created":"2018-12-19T14:19:50Z","relation":"main_file","access_level":"open_access","file_name":"FileS9.txt","checksum":"0fe7a58a030b11bf3b9c8ff7a7addcae","date_updated":"2020-07-14T12:47:11Z","file_id":"5766"}],"keyword":["(mal)adaptation","pleiotropy","selective constraint","evo-devo","gene expression","Drosophila melanogaster"],"date_published":"2018-12-19T00:00:00Z","month":"12","date_created":"2018-12-19T14:22:35Z","status":"public","oa_version":"Published Version","date_updated":"2024-02-21T13:59:18Z","type":"research_data","year":"2018","contributor":[{"id":"32DF5794-F248-11E8-B48F-1D18A9856A87","first_name":"Christelle","last_name":"Fraisse"},{"id":"33AB266C-F248-11E8-B48F-1D18A9856A87","first_name":"Gemma","last_name":"Puixeu Sala"},{"orcid":"0000-0002-4579-8306","id":"49E1C5C6-F248-11E8-B48F-1D18A9856A87","first_name":"Beatriz","last_name":"Vicoso"}],"day":"19","citation":{"chicago":"Fraisse, Christelle. “Supplementary Files for ‘Pleiotropy Modulates the Efficacy of Selection in Drosophila Melanogaster.’” Institute of Science and Technology Austria, 2018. <a href=\"https://doi.org/10.15479/at:ista:/5757\">https://doi.org/10.15479/at:ista:/5757</a>.","short":"C. Fraisse, (2018).","ista":"Fraisse C. 2018. Supplementary Files for ‘Pleiotropy modulates the efficacy of selection in Drosophila melanogaster’, Institute of Science and Technology Austria, <a href=\"https://doi.org/10.15479/at:ista:/5757\">10.15479/at:ista:/5757</a>.","ama":"Fraisse C. Supplementary Files for “Pleiotropy modulates the efficacy of selection in Drosophila melanogaster.” 2018. doi:<a href=\"https://doi.org/10.15479/at:ista:/5757\">10.15479/at:ista:/5757</a>","ieee":"C. Fraisse, “Supplementary Files for ‘Pleiotropy modulates the efficacy of selection in Drosophila melanogaster.’” Institute of Science and Technology Austria, 2018.","apa":"Fraisse, C. (2018). Supplementary Files for “Pleiotropy modulates the efficacy of selection in Drosophila melanogaster.” Institute of Science and Technology Austria. <a href=\"https://doi.org/10.15479/at:ista:/5757\">https://doi.org/10.15479/at:ista:/5757</a>","mla":"Fraisse, Christelle. <i>Supplementary Files for “Pleiotropy Modulates the Efficacy of Selection in Drosophila Melanogaster.”</i> Institute of Science and Technology Austria, 2018, doi:<a href=\"https://doi.org/10.15479/at:ista:/5757\">10.15479/at:ista:/5757</a>."},"article_processing_charge":"No","user_id":"2DF688A6-F248-11E8-B48F-1D18A9856A87","author":[{"last_name":"Fraisse","first_name":"Christelle","orcid":"0000-0001-8441-5075","full_name":"Fraisse, Christelle","id":"32DF5794-F248-11E8-B48F-1D18A9856A87"}],"project":[{"name":"International IST Postdoc Fellowship Programme","grant_number":"291734","_id":"25681D80-B435-11E9-9278-68D0E5697425","call_identifier":"FP7"}],"abstract":[{"lang":"eng","text":"File S1. Variant Calling Format file of the ingroup: 197 haploid sequences of D. melanogaster from Zambia (Africa) aligned to the D. melanogaster 5.57 reference genome.\r\n\r\nFile S2. Variant Calling Format file of the outgroup: 1 haploid sequence of D. simulans aligned to the D. melanogaster 5.57 reference genome.\r\n\r\nFile S3. Annotations of each transcript in coding regions with SNPeff: Ps (# of synonymous polymorphic sites); Pn (# of non-synonymous polymorphic sites); Ds (# of synonymous divergent sites); Dn (# of non-synonymous divergent sites); DoS; ⍺ MK . All variants were included.\r\n\r\nFile S4. Annotations of each transcript in non-coding regions with SNPeff: Ps (# of synonymous polymorphic sites); Pu (# of UTR polymorphic sites); Ds (# of synonymous divergent sites); Du (# of UTR divergent sites); DoS; ⍺ MK . All variants were included.\r\n\r\nFile S5. Annotations of each transcript in coding regions with SNPGenie: Ps (# of synonymous polymorphic sites); πs (synonymous diversity); Ss_p (total # of synonymous sites in the polymorphism data); Pn (# of non-synonymous polymorphic sites); πn (non-synonymous diversity); Sn_p (total # of non-synonymous sites in the polymorphism data); Ds (# of synonymous divergent sites); ks (synonymous evolutionary rate); Ss_d (total # of synonymous sites in the divergence data); Dn (# of non-synonymous divergent sites); kn (non-synonymous evolutionary rate); Sn_d (total # of non-\r\nsynonymous sites in the divergence data); DoS; ⍺ MK . All variants were included.\r\n\r\nFile S6. Gene expression values (RPKM summed over all transcripts) for each sample. Values were quantile-normalized across all samples.\r\n\r\nFile S7. Final dataset with all covariates, ⍺ MK , ωA MK and DoS for coding sites, excluding variants below 5% frequency.\r\n\r\nFile S8. Final dataset with all covariates, ⍺ MK , ωA MK and DoS for non-coding sites, excluding variants below 5%\r\nfrequency.\r\n\r\nFile S9. Final dataset with all covariates, ⍺ EWK , ωA EWK and deleterious SFS for coding sites obtained with the Eyre-Walker and Keightley method on binned data and using all variants."}],"ec_funded":1,"title":"Supplementary Files for \"Pleiotropy modulates the efficacy of selection in Drosophila melanogaster\"","has_accepted_license":"1","_id":"5757","department":[{"_id":"BeVi"},{"_id":"NiBa"}],"ddc":["576"],"oa":1,"related_material":{"record":[{"status":"public","relation":"research_paper","id":"6089"}]},"doi":"10.15479/at:ista:/5757"},{"file_date_updated":"2020-07-14T12:47:15Z","publisher":"Oxford University Press","volume":10,"issue":"3","date_created":"2019-02-14T12:13:52Z","month":"03","status":"public","intvolume":"        10","isi":1,"tmp":{"name":"Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)","image":"/images/cc_by_nc.png","short":"CC BY-NC (4.0)","legal_code_url":"https://creativecommons.org/licenses/by-nc/4.0/legalcode"},"year":"2018","citation":{"ista":"Kincaid-Smith J, Picard MAL, Cosseau C, Boissier J, Severac D, Grunau C, Toulza E. 2018. Parent-of-Origin-Dependent Gene Expression in Male and Female Schistosome Parasites. Genome Biology and Evolution. 10(3), 840–856.","chicago":"Kincaid-Smith, Julien, Marion A L Picard, Céline Cosseau, Jérôme Boissier, Dany Severac, Christoph Grunau, and Eve Toulza. “Parent-of-Origin-Dependent Gene Expression in Male and Female Schistosome Parasites.” <i>Genome Biology and Evolution</i>. Oxford University Press, 2018. <a href=\"https://doi.org/10.1093/gbe/evy037\">https://doi.org/10.1093/gbe/evy037</a>.","short":"J. Kincaid-Smith, M.A.L. Picard, C. Cosseau, J. Boissier, D. Severac, C. Grunau, E. Toulza, Genome Biology and Evolution 10 (2018) 840–856.","ama":"Kincaid-Smith J, Picard MAL, Cosseau C, et al. Parent-of-Origin-Dependent Gene Expression in Male and Female Schistosome Parasites. <i>Genome Biology and Evolution</i>. 2018;10(3):840-856. doi:<a href=\"https://doi.org/10.1093/gbe/evy037\">10.1093/gbe/evy037</a>","ieee":"J. Kincaid-Smith <i>et al.</i>, “Parent-of-Origin-Dependent Gene Expression in Male and Female Schistosome Parasites,” <i>Genome Biology and Evolution</i>, vol. 10, no. 3. Oxford University Press, pp. 840–856, 2018.","apa":"Kincaid-Smith, J., Picard, M. A. L., Cosseau, C., Boissier, J., Severac, D., Grunau, C., &#38; Toulza, E. (2018). Parent-of-Origin-Dependent Gene Expression in Male and Female Schistosome Parasites. <i>Genome Biology and Evolution</i>. Oxford University Press. <a href=\"https://doi.org/10.1093/gbe/evy037\">https://doi.org/10.1093/gbe/evy037</a>","mla":"Kincaid-Smith, Julien, et al. “Parent-of-Origin-Dependent Gene Expression in Male and Female Schistosome Parasites.” <i>Genome Biology and Evolution</i>, vol. 10, no. 3, Oxford University Press, 2018, pp. 840–56, doi:<a href=\"https://doi.org/10.1093/gbe/evy037\">10.1093/gbe/evy037</a>."},"author":[{"last_name":"Kincaid-Smith","first_name":"Julien","full_name":"Kincaid-Smith, Julien"},{"id":"2C921A7A-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0002-8101-2518","full_name":"Picard, Marion A L","last_name":"Picard","first_name":"Marion A L"},{"full_name":"Cosseau, Céline","last_name":"Cosseau","first_name":"Céline"},{"first_name":"Jérôme","last_name":"Boissier","full_name":"Boissier, Jérôme"},{"last_name":"Severac","first_name":"Dany","full_name":"Severac, Dany"},{"full_name":"Grunau, Christoph","first_name":"Christoph","last_name":"Grunau"},{"last_name":"Toulza","first_name":"Eve","full_name":"Toulza, Eve"}],"quality_controlled":"1","publication_status":"published","abstract":[{"text":"Schistosomes are the causative agents of schistosomiasis, a neglected tropical disease affecting over 230 million people worldwide.Additionally to their major impact on human health, they are also models of choice in evolutionary biology. These parasitic flatwormsare unique among the common hermaphroditic trematodes as they have separate sexes. This so-called “evolutionary scandal”displays a female heterogametic genetic sex-determination system (ZZ males and ZW females), as well as a pronounced adult sexualdimorphism. These phenotypic differences are determined by a shared set of genes in both sexes, potentially leading to intralocussexual conflicts. To resolve these conflicts in sexually selected traits, molecular mechanisms such as sex-biased gene expression couldoccur, but parent-of-origin gene expression also provides an alternative. In this work we investigated the latter mechanism, that is,genes expressed preferentially from either the maternal or the paternal allele, inSchistosoma mansonispecies. To this end, tran-scriptomes from male and female hybrid adults obtained by strain crosses were sequenced. Strain-specific single nucleotide poly-morphism (SNP) markers allowed us to discriminate the parental origin, while reciprocal crosses helped to differentiate parentalexpression from strain-specific expression. We identified genes containing SNPs expressed in a parent-of-origin manner consistentwith paternal and maternal imprints. Although the majority of the SNPs was identified in mitochondrial and Z-specific loci, theremaining SNPs found in male and female transcriptomes were situated in genes that have the potential to explain sexual differencesin schistosome parasites. Furthermore, we identified and validated four new Z-specific scaffolds.","lang":"eng"}],"title":"Parent-of-Origin-Dependent Gene Expression in Male and Female Schistosome Parasites","publication":"Genome Biology and Evolution","ddc":["570"],"oa":1,"_id":"5989","date_published":"2018-03-01T00:00:00Z","external_id":{"isi":["000429483700013"]},"file":[{"creator":"dernst","content_type":"application/pdf","file_size":529755,"date_created":"2019-02-14T12:20:01Z","relation":"main_file","access_level":"open_access","checksum":"736a459cb77de5824354466bb0331caf","file_name":"2018_GBE_Kincaid_Smith.pdf","date_updated":"2020-07-14T12:47:15Z","file_id":"5991"}],"page":"840-856","publication_identifier":{"issn":["1759-6653"]},"scopus_import":"1","date_updated":"2023-09-19T14:39:08Z","type":"journal_article","oa_version":"Published Version","day":"01","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","article_processing_charge":"No","doi":"10.1093/gbe/evy037","language":[{"iso":"eng"}],"has_accepted_license":"1","department":[{"_id":"BeVi"}]},{"year":"2018","tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"quality_controlled":"1","author":[{"id":"3A7E01BC-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0001-9638-1220","full_name":"Gammerdinger, William J","first_name":"William J","last_name":"Gammerdinger"},{"full_name":"Kocher, Thomas","last_name":"Kocher","first_name":"Thomas"}],"citation":{"ieee":"W. J. Gammerdinger and T. Kocher, “Unusual diversity of sex chromosomes in African cichlid fishes,” <i>Genes</i>, vol. 9, no. 10. MDPI AG, 2018.","ama":"Gammerdinger WJ, Kocher T. Unusual diversity of sex chromosomes in African cichlid fishes. <i>Genes</i>. 2018;9(10). doi:<a href=\"https://doi.org/10.3390/genes9100480\">10.3390/genes9100480</a>","ista":"Gammerdinger WJ, Kocher T. 2018. Unusual diversity of sex chromosomes in African cichlid fishes. Genes. 9(10), 480.","short":"W.J. Gammerdinger, T. Kocher, Genes 9 (2018).","chicago":"Gammerdinger, William J, and Thomas Kocher. “Unusual Diversity of Sex Chromosomes in African Cichlid Fishes.” <i>Genes</i>. MDPI AG, 2018. <a href=\"https://doi.org/10.3390/genes9100480\">https://doi.org/10.3390/genes9100480</a>.","mla":"Gammerdinger, William J., and Thomas Kocher. “Unusual Diversity of Sex Chromosomes in African Cichlid Fishes.” <i>Genes</i>, vol. 9, no. 10, 480, MDPI AG, 2018, doi:<a href=\"https://doi.org/10.3390/genes9100480\">10.3390/genes9100480</a>.","apa":"Gammerdinger, W. J., &#38; Kocher, T. (2018). Unusual diversity of sex chromosomes in African cichlid fishes. <i>Genes</i>. MDPI AG. <a href=\"https://doi.org/10.3390/genes9100480\">https://doi.org/10.3390/genes9100480</a>"},"abstract":[{"text":"African cichlids display a remarkable assortment of jaw morphologies, pigmentation patterns, and mating behaviors. In addition to this previously documented diversity, recent studies have documented a rich diversity of sex chromosomes within these fishes. Here we review the known sex-determination network within vertebrates, and the extraordinary number of sex chromosomes systems segregating in African cichlids. We also propose a model for understanding the unusual number of sex chromosome systems within this clade.","lang":"eng"}],"publication_status":"published","project":[{"_id":"25681D80-B435-11E9-9278-68D0E5697425","call_identifier":"FP7","name":"International IST Postdoc Fellowship Programme","grant_number":"291734"}],"_id":"63","oa":1,"ddc":["570"],"publication":"Genes","title":"Unusual diversity of sex chromosomes in African cichlid fishes","publisher":"MDPI AG","file_date_updated":"2020-07-14T12:47:27Z","issue":"10","volume":9,"article_number":"480","status":"public","month":"10","date_created":"2018-12-11T11:44:26Z","isi":1,"publist_id":"7991","intvolume":"         9","day":"04","oa_version":"Published Version","type":"journal_article","date_updated":"2023-09-19T10:37:03Z","article_processing_charge":"No","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","acknowledgement":"NSF DEB-1830753 and ISTPlus Fellowship","department":[{"_id":"BeVi"}],"has_accepted_license":"1","doi":"10.3390/genes9100480","language":[{"iso":"eng"}],"ec_funded":1,"external_id":{"isi":["000448656700018"]},"file":[{"access_level":"open_access","checksum":"bec527692e2c9b56919c0429634ff337","file_name":"2018_Genes_Gammerdinger.pdf","file_id":"5743","date_updated":"2020-07-14T12:47:27Z","file_size":1415791,"creator":"dernst","content_type":"application/pdf","date_created":"2018-12-18T09:54:46Z","relation":"main_file"}],"date_published":"2018-10-04T00:00:00Z","scopus_import":"1"},{"main_file_link":[{"url":"https://doi.org/10.5061/dryad.51d4r","open_access":"1"}],"citation":{"ista":"Harrison MC, Jongepier E, Robertson HM, Arning N, Bitard-Feildel T, Chao H, Childers CP, Dinh H, Doddapaneni H, Dugan S, Gowin J, Greiner C, Han Y, Hu H, Hughes DST, Huylmans AK, Kemena C, Kremer LPM, Lee SL, Lopez-Ezquerra A, Mallet L, Monroy-Kuhn JM, Moser A, Murali SC, Muzny DM, Otani S, Piulachs M-D, Poelchau M, Qu J, Schaub F, Wada-Katsumata A, Worley KC, Xie Q, Ylla G, Poulsen M, Gibbs RA, Schal C, Richards S, Belles X, Korb J, Bornberg-Bauer E. 2018. Data from: Hemimetabolous genomes reveal molecular basis of termite eusociality, Dryad, <a href=\"https://doi.org/10.5061/dryad.51d4r\">10.5061/dryad.51d4r</a>.","short":"M.C. Harrison, E. Jongepier, H.M. Robertson, N. Arning, T. Bitard-Feildel, H. Chao, C.P. Childers, H. Dinh, H. Doddapaneni, S. Dugan, J. Gowin, C. Greiner, Y. Han, H. Hu, D.S.T. Hughes, A.K. Huylmans, C. Kemena, L.P.M. Kremer, S.L. Lee, A. Lopez-Ezquerra, L. Mallet, J.M. Monroy-Kuhn, A. Moser, S.C. Murali, D.M. Muzny, S. Otani, M.-D. Piulachs, M. Poelchau, J. Qu, F. Schaub, A. Wada-Katsumata, K.C. Worley, Q. Xie, G. Ylla, M. Poulsen, R.A. Gibbs, C. Schal, S. Richards, X. Belles, J. Korb, E. Bornberg-Bauer, (2018).","chicago":"Harrison, Mark C., Evelien Jongepier, Hugh M. Robertson, Nicolas Arning, Tristan Bitard-Feildel, Hsu Chao, Christopher P. Childers, et al. “Data from: Hemimetabolous Genomes Reveal Molecular Basis of Termite Eusociality.” Dryad, 2018. <a href=\"https://doi.org/10.5061/dryad.51d4r\">https://doi.org/10.5061/dryad.51d4r</a>.","ieee":"M. C. Harrison <i>et al.</i>, “Data from: Hemimetabolous genomes reveal molecular basis of termite eusociality.” Dryad, 2018.","ama":"Harrison MC, Jongepier E, Robertson HM, et al. Data from: Hemimetabolous genomes reveal molecular basis of termite eusociality. 2018. doi:<a href=\"https://doi.org/10.5061/dryad.51d4r\">10.5061/dryad.51d4r</a>","apa":"Harrison, M. C., Jongepier, E., Robertson, H. M., Arning, N., Bitard-Feildel, T., Chao, H., … Bornberg-Bauer, E. (2018). Data from: Hemimetabolous genomes reveal molecular basis of termite eusociality. Dryad. <a href=\"https://doi.org/10.5061/dryad.51d4r\">https://doi.org/10.5061/dryad.51d4r</a>","mla":"Harrison, Mark C., et al. <i>Data from: Hemimetabolous Genomes Reveal Molecular Basis of Termite Eusociality</i>. Dryad, 2018, doi:<a href=\"https://doi.org/10.5061/dryad.51d4r\">10.5061/dryad.51d4r</a>."},"author":[{"full_name":"Harrison, Mark C.","last_name":"Harrison","first_name":"Mark C."},{"last_name":"Jongepier","first_name":"Evelien","full_name":"Jongepier, Evelien"},{"full_name":"Robertson, Hugh M.","first_name":"Hugh M.","last_name":"Robertson"},{"last_name":"Arning","first_name":"Nicolas","full_name":"Arning, Nicolas"},{"last_name":"Bitard-Feildel","first_name":"Tristan","full_name":"Bitard-Feildel, Tristan"},{"full_name":"Chao, Hsu","last_name":"Chao","first_name":"Hsu"},{"full_name":"Childers, Christopher P.","last_name":"Childers","first_name":"Christopher P."},{"full_name":"Dinh, Huyen","first_name":"Huyen","last_name":"Dinh"},{"full_name":"Doddapaneni, Harshavardhan","first_name":"Harshavardhan","last_name":"Doddapaneni"},{"full_name":"Dugan, Shannon","first_name":"Shannon","last_name":"Dugan"},{"full_name":"Gowin, Johannes","last_name":"Gowin","first_name":"Johannes"},{"full_name":"Greiner, Carolin","last_name":"Greiner","first_name":"Carolin"},{"full_name":"Han, Yi","last_name":"Han","first_name":"Yi"},{"full_name":"Hu, Haofu","last_name":"Hu","first_name":"Haofu"},{"full_name":"Hughes, Daniel S. T.","first_name":"Daniel S. T.","last_name":"Hughes"},{"last_name":"Huylmans","first_name":"Ann K","orcid":"0000-0001-8871-4961","full_name":"Huylmans, Ann K","id":"4C0A3874-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Kemena","first_name":"Carsten","full_name":"Kemena, Carsten"},{"last_name":"Kremer","first_name":"Lukas P. M.","full_name":"Kremer, Lukas P. M."},{"last_name":"Lee","first_name":"Sandra L.","full_name":"Lee, Sandra L."},{"last_name":"Lopez-Ezquerra","first_name":"Alberto","full_name":"Lopez-Ezquerra, Alberto"},{"full_name":"Mallet, Ludovic","first_name":"Ludovic","last_name":"Mallet"},{"first_name":"Jose M.","last_name":"Monroy-Kuhn","full_name":"Monroy-Kuhn, Jose M."},{"full_name":"Moser, Annabell","first_name":"Annabell","last_name":"Moser"},{"full_name":"Murali, Shwetha C.","first_name":"Shwetha C.","last_name":"Murali"},{"first_name":"Donna M.","last_name":"Muzny","full_name":"Muzny, Donna M."},{"last_name":"Otani","first_name":"Saria","full_name":"Otani, Saria"},{"last_name":"Piulachs","first_name":"Maria-Dolors","full_name":"Piulachs, Maria-Dolors"},{"last_name":"Poelchau","first_name":"Monica","full_name":"Poelchau, Monica"},{"full_name":"Qu, Jiaxin","last_name":"Qu","first_name":"Jiaxin"},{"full_name":"Schaub, Florentine","last_name":"Schaub","first_name":"Florentine"},{"last_name":"Wada-Katsumata","first_name":"Ayako","full_name":"Wada-Katsumata, Ayako"},{"first_name":"Kim C.","last_name":"Worley","full_name":"Worley, Kim C."},{"full_name":"Xie, Qiaolin","first_name":"Qiaolin","last_name":"Xie"},{"first_name":"Guillem","last_name":"Ylla","full_name":"Ylla, Guillem"},{"last_name":"Poulsen","first_name":"Michael","full_name":"Poulsen, Michael"},{"last_name":"Gibbs","first_name":"Richard A.","full_name":"Gibbs, Richard A."},{"last_name":"Schal","first_name":"Coby","full_name":"Schal, Coby"},{"full_name":"Richards, Stephen","first_name":"Stephen","last_name":"Richards"},{"full_name":"Belles, Xavier","first_name":"Xavier","last_name":"Belles"},{"full_name":"Korb, Judith","first_name":"Judith","last_name":"Korb"},{"full_name":"Bornberg-Bauer, Erich","first_name":"Erich","last_name":"Bornberg-Bauer"}],"user_id":"6785fbc1-c503-11eb-8a32-93094b40e1cf","article_processing_charge":"No","oa_version":"Published Version","date_updated":"2023-09-11T14:10:56Z","type":"research_data_reference","year":"2018","day":"12","title":"Data from: Hemimetabolous genomes reveal molecular basis of termite eusociality","_id":"9841","department":[{"_id":"BeVi"}],"related_material":{"record":[{"id":"448","status":"public","relation":"used_in_publication"}]},"doi":"10.5061/dryad.51d4r","oa":1,"abstract":[{"text":"Around 150 million years ago, eusocial termites evolved from within the cockroaches, 50 million years before eusocial Hymenoptera, such as bees and ants, appeared. Here, we report the 2-Gb genome of the German cockroach, Blattella germanica, and the 1.3-Gb genome of the drywood termite Cryptotermes secundus. We show evolutionary signatures of termite eusociality by comparing the genomes and transcriptomes of three termites and the cockroach against the background of 16 other eusocial and non-eusocial insects. Dramatic adaptive changes in genes underlying the production and perception of pheromones confirm the importance of chemical communication in the termites. These are accompanied by major changes in gene regulation and the molecular evolution of caste determination. Many of these results parallel molecular mechanisms of eusocial evolution in Hymenoptera. However, the specific solutions are remarkably different, thus revealing a striking case of convergence in one of the major evolutionary transitions in biological complexity.","lang":"eng"}],"date_published":"2018-12-12T00:00:00Z","publisher":"Dryad","month":"12","date_created":"2021-08-09T13:13:48Z","status":"public"},{"publication_identifier":{"eissn":["2056-3744"],"issn":[" 2056-3744"]},"file":[{"creator":"asandaue","content_type":"application/pdf","file_size":584606,"relation":"main_file","date_created":"2021-08-16T07:37:28Z","file_name":"2018_EvolutionLetters_Hollander.pdf","checksum":"997a78ac41c809975ca69cbdea441f88","access_level":"open_access","success":1,"file_id":"9916","date_updated":"2021-08-16T07:37:28Z"}],"external_id":{"isi":["000452990000002"],"pmid":["30564439"]},"date_published":"2018-12-13T00:00:00Z","page":"557-566","acknowledgement":"The authors express a special thanks to Dr Richard Willan at the Museum and Art Gallery of the Northern Territory for guidance and support in the field, and to Carole Smadja for reading and commenting on the manuscript. The authors thank the Government of Western Australia Department of Parks and Wildlife (license no. 009254) and Fishery Research Division (exemption no. 2262) for assistance with permits. Khalid Belkhir modified the coalescent sampler msnsam for the specific needs of this project and Martin Hirsch helped to set up the ABC pipeline and to modify the summary statistic calculator mscalc. The authors are grateful to the Crafoord Foundation for supporting this project. R.K.B., A.M.W., and L.D. were supported by grants from the Natural Environment Research Council, R.K.B. and A.M.W. were also supported by the European Research Council and R.K.B. and L.D. by the Leverhulme Trust. M.M.R. was supported by Consejo Nacional de Ciencia y Tecnología and Secretaría de Educación Pública, Mexico. G.B. was supported by the Centre for Animal Movement Research (CAnMove) financed by a Linnaeus grant (No. 349-2007-8690) from the Swedish Research Council and Lund University.","has_accepted_license":"1","department":[{"_id":"BeVi"}],"language":[{"iso":"eng"}],"doi":"10.1002/evl3.85","oa_version":"Published Version","date_updated":"2023-09-19T15:08:53Z","type":"journal_article","day":"13","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","article_processing_charge":"Yes","month":"12","date_created":"2021-08-16T07:30:00Z","status":"public","intvolume":"         2","isi":1,"file_date_updated":"2021-08-16T07:37:28Z","publisher":"Wiley","article_type":"letter_note","issue":"6","volume":2,"abstract":[{"lang":"eng","text":"The evolution of assortative mating is a key part of the speciation process. Stronger assortment, or greater divergence in mating traits, between species pairs with overlapping ranges is commonly observed, but possible causes of this pattern of reproductive character displacement are difficult to distinguish. We use a multidisciplinary approach to provide a rare example where it is possible to distinguish among hypotheses concerning the evolution of reproductive character displacement. We build on an earlier comparative analysis that illustrated a strong pattern of greater divergence in penis form between pairs of sister species with overlapping ranges than between allopatric sister-species pairs, in a large clade of marine gastropods (Littorinidae). We investigate both assortative mating and divergence in male genitalia in one of the sister-species pairs, discriminating among three contrasting processes each of which can generate a pattern of reproductive character displacement: reinforcement, reproductive interference and the Templeton effect. We demonstrate reproductive character displacement in assortative mating, but not in genital form between this pair of sister species and use demographic models to distinguish among the different processes. Our results support a model with no gene flow since secondary contact and thus favor reproductive interference as the cause of reproductive character displacement for mate choice, rather than reinforcement. High gene flow within species argues against the Templeton effect. Secondary contact appears to have had little impact on genital divergence."}],"publication_status":"published","pmid":1,"publication":"Evolution Letters","title":"Are assortative mating and genital divergence driven by reinforcement?","_id":"9915","oa":1,"related_material":{"record":[{"id":"9929","status":"public","relation":"research_data"}]},"ddc":["570"],"tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"year":"2018","citation":{"mla":"Hollander, Johan, et al. “Are Assortative Mating and Genital Divergence Driven by Reinforcement?” <i>Evolution Letters</i>, vol. 2, no. 6, Wiley, 2018, pp. 557–66, doi:<a href=\"https://doi.org/10.1002/evl3.85\">10.1002/evl3.85</a>.","apa":"Hollander, J., Montaño-Rendón, M., Bianco, G., Yang, X., Westram, A. M., Duvaux, L., … Butlin, R. K. (2018). Are assortative mating and genital divergence driven by reinforcement? <i>Evolution Letters</i>. Wiley. <a href=\"https://doi.org/10.1002/evl3.85\">https://doi.org/10.1002/evl3.85</a>","ama":"Hollander J, Montaño-Rendón M, Bianco G, et al. Are assortative mating and genital divergence driven by reinforcement? <i>Evolution Letters</i>. 2018;2(6):557-566. doi:<a href=\"https://doi.org/10.1002/evl3.85\">10.1002/evl3.85</a>","ieee":"J. Hollander <i>et al.</i>, “Are assortative mating and genital divergence driven by reinforcement?,” <i>Evolution Letters</i>, vol. 2, no. 6. Wiley, pp. 557–566, 2018.","chicago":"Hollander, Johan, Mauricio Montaño-Rendón, Giuseppe Bianco, Xi Yang, Anja M Westram, Ludovic Duvaux, David G. Reid, and Roger K. Butlin. “Are Assortative Mating and Genital Divergence Driven by Reinforcement?” <i>Evolution Letters</i>. Wiley, 2018. <a href=\"https://doi.org/10.1002/evl3.85\">https://doi.org/10.1002/evl3.85</a>.","short":"J. Hollander, M. Montaño-Rendón, G. Bianco, X. Yang, A.M. Westram, L. Duvaux, D.G. Reid, R.K. Butlin, Evolution Letters 2 (2018) 557–566.","ista":"Hollander J, Montaño-Rendón M, Bianco G, Yang X, Westram AM, Duvaux L, Reid DG, Butlin RK. 2018. Are assortative mating and genital divergence driven by reinforcement? Evolution Letters. 2(6), 557–566."},"quality_controlled":"1","author":[{"full_name":"Hollander, Johan","last_name":"Hollander","first_name":"Johan"},{"full_name":"Montaño-Rendón, Mauricio","last_name":"Montaño-Rendón","first_name":"Mauricio"},{"first_name":"Giuseppe","last_name":"Bianco","full_name":"Bianco, Giuseppe"},{"first_name":"Xi","last_name":"Yang","full_name":"Yang, Xi"},{"id":"3C147470-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-1050-4969","full_name":"Westram, Anja M","first_name":"Anja M","last_name":"Westram"},{"first_name":"Ludovic","last_name":"Duvaux","full_name":"Duvaux, Ludovic"},{"full_name":"Reid, David G.","last_name":"Reid","first_name":"David G."},{"full_name":"Butlin, Roger K.","last_name":"Butlin","first_name":"Roger K."}]},{"acknowledgement":"We are very grateful to people who helped with fieldwork, snail processing, and DNA extractions, particularly Laura Brettell, Mårten Duvetorp, Juan Galindo, Anne-Lise Liabot and Irena Senčić. We would also like to thank Magnus Alm Rosenblad and Mats Töpel for their contribution to assembling the Littorina saxatilis genome, Carl André, Pasi Rastas, and Romain Villoutreix for discussion, and two anonymous reviewers for their helpful comments on the manuscript. We are grateful to RapidGenomics for library preparation and sequencing. We thank the Natural Environment Research Council, the European Research Council and the Swedish Research Councils VR and Formas (Linnaeus grant to the Centre for Marine Evolutionary Biology and Tage Erlander Guest Professorship) for funding. P.C. was funded by the University of Sheffield Vice-chancellor's India scholarship. R.F. is funded by the European Union's Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement no. 706376. M. Raf. was supported by the Adlerbert Research Foundation.","language":[{"iso":"eng"}],"doi":"10.1002/evl3.74","department":[{"_id":"BeVi"}],"has_accepted_license":"1","date_updated":"2023-09-19T15:08:25Z","type":"journal_article","oa_version":"Published Version","day":"20","article_processing_charge":"Yes","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","publication_identifier":{"issn":["2056-3744"],"eissn":["2056-3744"]},"date_published":"2018-08-20T00:00:00Z","file":[{"access_level":"open_access","checksum":"8524e72507d521416be3f8ccfcd5e3f5","file_name":"2018_EvolutionLetters_Westram.pdf","date_updated":"2021-08-16T07:48:03Z","file_id":"9918","success":1,"content_type":"application/pdf","creator":"asandaue","file_size":764299,"date_created":"2021-08-16T07:48:03Z","relation":"main_file"}],"external_id":{"isi":["000446774400004"],"pmid":["30283683"]},"page":"297-309","publication_status":"published","abstract":[{"lang":"eng","text":"Adaptive divergence and speciation may happen despite opposition by gene flow. Identifying the genomic basis underlying divergence with gene flow is a major task in evolutionary genomics. Most approaches (e.g., outlier scans) focus on genomic regions of high differentiation. However, not all genomic architectures potentially underlying divergence are expected to show extreme differentiation. Here, we develop an approach that combines hybrid zone analysis (i.e., focuses on spatial patterns of allele frequency change) with system-specific simulations to identify loci inconsistent with neutral evolution. We apply this to a genome-wide SNP set from an ideally suited study organism, the intertidal snail Littorina saxatilis, which shows primary divergence between ecotypes associated with different shore habitats. We detect many SNPs with clinal patterns, most of which are consistent with neutrality. Among non-neutral SNPs, most are located within three large putative inversions differentiating ecotypes. Many non-neutral SNPs show relatively low levels of differentiation. We discuss potential reasons for this pattern, including loose linkage to selected variants, polygenic adaptation and a component of balancing selection within populations (which may be expected for inversions). Our work is in line with theory predicting a role for inversions in divergence, and emphasizes that genomic regions contributing to divergence may not always be accessible with methods purely based on allele frequency differences. These conclusions call for approaches that take spatial patterns of allele frequency change into account in other systems."}],"title":"Clines on the seashore: The genomic architecture underlying rapid divergence in the face of gene flow","publication":"Evolution Letters","pmid":1,"related_material":{"record":[{"id":"9930","relation":"research_data","status":"public"}]},"ddc":["570"],"oa":1,"_id":"9917","tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"year":"2018","citation":{"apa":"Westram, A. M., Rafajlović, M., Chaube, P., Faria, R., Larsson, T., Panova, M., … Butlin, R. (2018). Clines on the seashore: The genomic architecture underlying rapid divergence in the face of gene flow. <i>Evolution Letters</i>. Wiley. <a href=\"https://doi.org/10.1002/evl3.74\">https://doi.org/10.1002/evl3.74</a>","mla":"Westram, Anja M., et al. “Clines on the Seashore: The Genomic Architecture Underlying Rapid Divergence in the Face of Gene Flow.” <i>Evolution Letters</i>, vol. 2, no. 4, Wiley, 2018, pp. 297–309, doi:<a href=\"https://doi.org/10.1002/evl3.74\">10.1002/evl3.74</a>.","ieee":"A. M. Westram <i>et al.</i>, “Clines on the seashore: The genomic architecture underlying rapid divergence in the face of gene flow,” <i>Evolution Letters</i>, vol. 2, no. 4. Wiley, pp. 297–309, 2018.","ama":"Westram AM, Rafajlović M, Chaube P, et al. Clines on the seashore: The genomic architecture underlying rapid divergence in the face of gene flow. <i>Evolution Letters</i>. 2018;2(4):297-309. doi:<a href=\"https://doi.org/10.1002/evl3.74\">10.1002/evl3.74</a>","chicago":"Westram, Anja M, Marina Rafajlović, Pragya Chaube, Rui Faria, Tomas Larsson, Marina Panova, Mark Ravinet, et al. “Clines on the Seashore: The Genomic Architecture Underlying Rapid Divergence in the Face of Gene Flow.” <i>Evolution Letters</i>. Wiley, 2018. <a href=\"https://doi.org/10.1002/evl3.74\">https://doi.org/10.1002/evl3.74</a>.","short":"A.M. Westram, M. Rafajlović, P. Chaube, R. Faria, T. Larsson, M. Panova, M. Ravinet, A. Blomberg, B. Mehlig, K. Johannesson, R. Butlin, Evolution Letters 2 (2018) 297–309.","ista":"Westram AM, Rafajlović M, Chaube P, Faria R, Larsson T, Panova M, Ravinet M, Blomberg A, Mehlig B, Johannesson K, Butlin R. 2018. Clines on the seashore: The genomic architecture underlying rapid divergence in the face of gene flow. Evolution Letters. 2(4), 297–309."},"author":[{"id":"3C147470-F248-11E8-B48F-1D18A9856A87","orcid":"0000-0003-1050-4969","full_name":"Westram, Anja M","last_name":"Westram","first_name":"Anja M"},{"first_name":"Marina","last_name":"Rafajlović","full_name":"Rafajlović, Marina"},{"full_name":"Chaube, Pragya","last_name":"Chaube","first_name":"Pragya"},{"full_name":"Faria, Rui","last_name":"Faria","first_name":"Rui"},{"full_name":"Larsson, Tomas","last_name":"Larsson","first_name":"Tomas"},{"first_name":"Marina","last_name":"Panova","full_name":"Panova, Marina"},{"first_name":"Mark","last_name":"Ravinet","full_name":"Ravinet, Mark"},{"full_name":"Blomberg, Anders","last_name":"Blomberg","first_name":"Anders"},{"first_name":"Bernhard","last_name":"Mehlig","full_name":"Mehlig, Bernhard"},{"last_name":"Johannesson","first_name":"Kerstin","full_name":"Johannesson, Kerstin"},{"full_name":"Butlin, Roger","first_name":"Roger","last_name":"Butlin"}],"quality_controlled":"1","date_created":"2021-08-16T07:45:38Z","month":"08","status":"public","intvolume":"         2","isi":1,"file_date_updated":"2021-08-16T07:48:03Z","publisher":"Wiley","article_type":"letter_note","volume":2,"issue":"4"},{"abstract":[{"text":"The evolution of assortative mating is a key part of the speciation process. Stronger assortment, or greater divergence in mating traits, between species pairs with overlapping ranges is commonly observed, but possible causes of this pattern of reproductive character displacement are difficult to distinguish. We use a multidisciplinary approach to provide a rare example where it is possible to distinguish among hypotheses concerning the evolution of reproductive character displacement. We build on an earlier comparative analysis that illustrated a strong pattern of greater divergence in penis form between pairs of sister species with overlapping ranges than between allopatric sister-species pairs, in a large clade of marine gastropods (Littorinidae). We investigate both assortative mating and divergence in male genitalia in one of the sister-species pairs, discriminating among three contrasting processes each of which can generate a pattern of reproductive character displacement: reinforcement, reproductive interference and the Templeton effect. We demonstrate reproductive character displacement in assortative mating, but not in genital form between this pair of sister species and use demographic models to distinguish among the different processes. Our results support a model with no gene flow since secondary contact and thus favour reproductive interference as the cause of reproductive character displacement for mate choice, rather than reinforcement. High gene flow within species argues against the Templeton effect. Secondary contact appears to have had little impact on genital divergence.","lang":"eng"}],"related_material":{"record":[{"relation":"used_in_publication","status":"public","id":"9915"}]},"doi":"10.5061/dryad.51sd2p5","oa":1,"_id":"9929","department":[{"_id":"BeVi"}],"title":"Data from: Are assortative mating and genital divergence driven by reinforcement?","day":"17","year":"2018","date_updated":"2023-09-19T15:08:53Z","type":"research_data_reference","oa_version":"Published Version","user_id":"6785fbc1-c503-11eb-8a32-93094b40e1cf","article_processing_charge":"No","author":[{"first_name":"Johan","last_name":"Hollander","full_name":"Hollander, Johan"},{"full_name":"Montaño-Rendón, Mauricio","first_name":"Mauricio","last_name":"Montaño-Rendón"},{"full_name":"Bianco, Giuseppe","first_name":"Giuseppe","last_name":"Bianco"},{"last_name":"Yang","first_name":"Xi","full_name":"Yang, Xi"},{"last_name":"Westram","first_name":"Anja M","id":"3C147470-F248-11E8-B48F-1D18A9856A87","full_name":"Westram, Anja M","orcid":"0000-0003-1050-4969"},{"last_name":"Duvaux","first_name":"Ludovic","full_name":"Duvaux, Ludovic"},{"full_name":"Reid, David G.","first_name":"David G.","last_name":"Reid"},{"full_name":"Butlin, Roger K.","last_name":"Butlin","first_name":"Roger K."}],"citation":{"mla":"Hollander, Johan, et al. <i>Data from: Are Assortative Mating and Genital Divergence Driven by Reinforcement?</i> Dryad, 2018, doi:<a href=\"https://doi.org/10.5061/dryad.51sd2p5\">10.5061/dryad.51sd2p5</a>.","apa":"Hollander, J., Montaño-Rendón, M., Bianco, G., Yang, X., Westram, A. M., Duvaux, L., … Butlin, R. K. (2018). Data from: Are assortative mating and genital divergence driven by reinforcement? Dryad. <a href=\"https://doi.org/10.5061/dryad.51sd2p5\">https://doi.org/10.5061/dryad.51sd2p5</a>","ieee":"J. Hollander <i>et al.</i>, “Data from: Are assortative mating and genital divergence driven by reinforcement?” Dryad, 2018.","ama":"Hollander J, Montaño-Rendón M, Bianco G, et al. Data from: Are assortative mating and genital divergence driven by reinforcement? 2018. doi:<a href=\"https://doi.org/10.5061/dryad.51sd2p5\">10.5061/dryad.51sd2p5</a>","ista":"Hollander J, Montaño-Rendón M, Bianco G, Yang X, Westram AM, Duvaux L, Reid DG, Butlin RK. 2018. Data from: Are assortative mating and genital divergence driven by reinforcement?, Dryad, <a href=\"https://doi.org/10.5061/dryad.51sd2p5\">10.5061/dryad.51sd2p5</a>.","short":"J. Hollander, M. Montaño-Rendón, G. Bianco, X. Yang, A.M. Westram, L. Duvaux, D.G. Reid, R.K. Butlin, (2018).","chicago":"Hollander, Johan, Mauricio Montaño-Rendón, Giuseppe Bianco, Xi Yang, Anja M Westram, Ludovic Duvaux, David G. Reid, and Roger K. Butlin. “Data from: Are Assortative Mating and Genital Divergence Driven by Reinforcement?” Dryad, 2018. <a href=\"https://doi.org/10.5061/dryad.51sd2p5\">https://doi.org/10.5061/dryad.51sd2p5</a>."},"main_file_link":[{"url":"https://doi.org/10.5061/dryad.51sd2p5","open_access":"1"}],"status":"public","date_created":"2021-08-17T08:51:06Z","month":"10","publisher":"Dryad","date_published":"2018-10-17T00:00:00Z"},{"author":[{"full_name":"Westram, Anja M","orcid":"0000-0003-1050-4969","id":"3C147470-F248-11E8-B48F-1D18A9856A87","last_name":"Westram","first_name":"Anja M"},{"last_name":"Rafajlović","first_name":"Marina","full_name":"Rafajlović, Marina"},{"full_name":"Chaube, Pragya","last_name":"Chaube","first_name":"Pragya"},{"full_name":"Faria, Rui","first_name":"Rui","last_name":"Faria"},{"last_name":"Larsson","first_name":"Tomas","full_name":"Larsson, Tomas"},{"last_name":"Panova","first_name":"Marina","full_name":"Panova, Marina"},{"full_name":"Ravinet, Mark","first_name":"Mark","last_name":"Ravinet"},{"first_name":"Anders","last_name":"Blomberg","full_name":"Blomberg, Anders"},{"last_name":"Mehlig","first_name":"Bernhard","full_name":"Mehlig, Bernhard"},{"full_name":"Johannesson, Kerstin","last_name":"Johannesson","first_name":"Kerstin"},{"last_name":"Butlin","first_name":"Roger","full_name":"Butlin, Roger"}],"article_processing_charge":"No","user_id":"6785fbc1-c503-11eb-8a32-93094b40e1cf","main_file_link":[{"open_access":"1","url":"https://doi.org/10.5061/dryad.bp25b65"}],"citation":{"ieee":"A. M. Westram <i>et al.</i>, “Data from: Clines on the seashore: the genomic architecture underlying rapid divergence in the face of gene flow.” Dryad, 2018.","ama":"Westram AM, Rafajlović M, Chaube P, et al. Data from: Clines on the seashore: the genomic architecture underlying rapid divergence in the face of gene flow. 2018. doi:<a href=\"https://doi.org/10.5061/dryad.bp25b65\">10.5061/dryad.bp25b65</a>","chicago":"Westram, Anja M, Marina Rafajlović, Pragya Chaube, Rui Faria, Tomas Larsson, Marina Panova, Mark Ravinet, et al. “Data from: Clines on the Seashore: The Genomic Architecture Underlying Rapid Divergence in the Face of Gene Flow.” Dryad, 2018. <a href=\"https://doi.org/10.5061/dryad.bp25b65\">https://doi.org/10.5061/dryad.bp25b65</a>.","short":"A.M. Westram, M. Rafajlović, P. Chaube, R. Faria, T. Larsson, M. Panova, M. Ravinet, A. Blomberg, B. Mehlig, K. Johannesson, R. Butlin, (2018).","ista":"Westram AM, Rafajlović M, Chaube P, Faria R, Larsson T, Panova M, Ravinet M, Blomberg A, Mehlig B, Johannesson K, Butlin R. 2018. Data from: Clines on the seashore: the genomic architecture underlying rapid divergence in the face of gene flow, Dryad, <a href=\"https://doi.org/10.5061/dryad.bp25b65\">10.5061/dryad.bp25b65</a>.","apa":"Westram, A. M., Rafajlović, M., Chaube, P., Faria, R., Larsson, T., Panova, M., … Butlin, R. (2018). Data from: Clines on the seashore: the genomic architecture underlying rapid divergence in the face of gene flow. Dryad. <a href=\"https://doi.org/10.5061/dryad.bp25b65\">https://doi.org/10.5061/dryad.bp25b65</a>","mla":"Westram, Anja M., et al. <i>Data from: Clines on the Seashore: The Genomic Architecture Underlying Rapid Divergence in the Face of Gene Flow</i>. Dryad, 2018, doi:<a href=\"https://doi.org/10.5061/dryad.bp25b65\">10.5061/dryad.bp25b65</a>."},"year":"2018","day":"23","oa_version":"Published Version","date_updated":"2023-09-19T15:08:24Z","type":"research_data_reference","department":[{"_id":"BeVi"}],"_id":"9930","oa":1,"related_material":{"record":[{"status":"public","relation":"used_in_publication","id":"9917"}]},"doi":"10.5061/dryad.bp25b65","title":"Data from: Clines on the seashore: the genomic architecture underlying rapid divergence in the face of gene flow","abstract":[{"text":"Adaptive divergence and speciation may happen despite opposition by gene flow. Identifying the genomic basis underlying divergence with gene flow is a major task in evolutionary genomics. Most approaches (e.g. outlier scans) focus on genomic regions of high differentiation. However, not all genomic architectures potentially underlying divergence are expected to show extreme differentiation. Here, we develop an approach that combines hybrid zone analysis (i.e. focuses on spatial patterns of allele frequency change) with system-specific simulations to identify loci inconsistent with neutral evolution. We apply this to a genome-wide SNP set from an ideally-suited study organism, the intertidal snail Littorina saxatilis, which shows primary divergence between ecotypes associated with different shore habitats. We detect many SNPs with clinal patterns, most of which are consistent with neutrality. Among non-neutral SNPs, most are located within three large putative inversions differentiating ecotypes. Many non-neutral SNPs show relatively low levels of differentiation. We discuss potential reasons for this pattern, including loose linkage to selected variants, polygenic adaptation and a component of balancing selection within populations (which may be expected for inversions). Our work is in line with theory predicting a role for inversions in divergence, and emphasises that genomic regions contributing to divergence may not always be accessible with methods purely based on allele frequency differences. These conclusions call for approaches that take spatial patterns of allele frequency change into account in other systems.","lang":"eng"}],"date_published":"2018-07-23T00:00:00Z","publisher":"Dryad","status":"public","month":"07","date_created":"2021-08-17T08:58:47Z"},{"publisher":"Springer Nature","file_date_updated":"2020-07-14T12:46:30Z","pubrep_id":"969","volume":2,"issue":"3","status":"public","month":"02","date_created":"2018-12-11T11:46:32Z","isi":1,"publist_id":"7375","intvolume":"         2","year":"2018","tmp":{"image":"/images/cc_by.png","name":"Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)","short":"CC BY (4.0)","legal_code_url":"https://creativecommons.org/licenses/by/4.0/legalcode"},"quality_controlled":"1","author":[{"first_name":"Mark","last_name":"Harrison","full_name":"Harrison, Mark"},{"first_name":"Evelien","last_name":"Jongepier","full_name":"Jongepier, Evelien"},{"full_name":"Robertson, Hugh","first_name":"Hugh","last_name":"Robertson"},{"first_name":"Nicolas","last_name":"Arning","full_name":"Arning, Nicolas"},{"full_name":"Bitard Feildel, Tristan","last_name":"Bitard Feildel","first_name":"Tristan"},{"full_name":"Chao, Hsu","first_name":"Hsu","last_name":"Chao"},{"full_name":"Childers, Christopher","last_name":"Childers","first_name":"Christopher"},{"last_name":"Dinh","first_name":"Huyen","full_name":"Dinh, Huyen"},{"full_name":"Doddapaneni, Harshavardhan","last_name":"Doddapaneni","first_name":"Harshavardhan"},{"last_name":"Dugan","first_name":"Shannon","full_name":"Dugan, Shannon"},{"first_name":"Johannes","last_name":"Gowin","full_name":"Gowin, Johannes"},{"last_name":"Greiner","first_name":"Carolin","full_name":"Greiner, Carolin"},{"last_name":"Han","first_name":"Yi","full_name":"Han, Yi"},{"first_name":"Haofu","last_name":"Hu","full_name":"Hu, Haofu"},{"last_name":"Hughes","first_name":"Daniel","full_name":"Hughes, Daniel"},{"first_name":"Ann K","last_name":"Huylmans","orcid":"0000-0001-8871-4961","full_name":"Huylmans, Ann K","id":"4C0A3874-F248-11E8-B48F-1D18A9856A87"},{"last_name":"Kemena","first_name":"Karsten","full_name":"Kemena, Karsten"},{"last_name":"Kremer","first_name":"Lukas","full_name":"Kremer, Lukas"},{"last_name":"Lee","first_name":"Sandra","full_name":"Lee, Sandra"},{"last_name":"López Ezquerra","first_name":"Alberto","full_name":"López Ezquerra, Alberto"},{"last_name":"Mallet","first_name":"Ludovic","full_name":"Mallet, Ludovic"},{"first_name":"Jose","last_name":"Monroy Kuhn","full_name":"Monroy Kuhn, Jose"},{"full_name":"Moser, Annabell","last_name":"Moser","first_name":"Annabell"},{"first_name":"Shwetha","last_name":"Murali","full_name":"Murali, Shwetha"},{"first_name":"Donna","last_name":"Muzny","full_name":"Muzny, Donna"},{"first_name":"Saria","last_name":"Otani","full_name":"Otani, Saria"},{"last_name":"Piulachs","first_name":"Maria","full_name":"Piulachs, Maria"},{"last_name":"Poelchau","first_name":"Monica","full_name":"Poelchau, Monica"},{"full_name":"Qu, Jiaxin","first_name":"Jiaxin","last_name":"Qu"},{"full_name":"Schaub, Florentine","first_name":"Florentine","last_name":"Schaub"},{"last_name":"Wada Katsumata","first_name":"Ayako","full_name":"Wada Katsumata, Ayako"},{"full_name":"Worley, Kim","first_name":"Kim","last_name":"Worley"},{"last_name":"Xie","first_name":"Qiaolin","full_name":"Xie, Qiaolin"},{"first_name":"Guillem","last_name":"Ylla","full_name":"Ylla, Guillem"},{"full_name":"Poulsen, Michael","last_name":"Poulsen","first_name":"Michael"},{"full_name":"Gibbs, Richard","first_name":"Richard","last_name":"Gibbs"},{"last_name":"Schal","first_name":"Coby","full_name":"Schal, Coby"},{"full_name":"Richards, Stephen","first_name":"Stephen","last_name":"Richards"},{"full_name":"Belles, Xavier","last_name":"Belles","first_name":"Xavier"},{"last_name":"Korb","first_name":"Judith","full_name":"Korb, Judith"},{"full_name":"Bornberg Bauer, Erich","first_name":"Erich","last_name":"Bornberg Bauer"}],"citation":{"ieee":"M. Harrison <i>et al.</i>, “Hemimetabolous genomes reveal molecular basis of termite eusociality,” <i>Nature Ecology and Evolution</i>, vol. 2, no. 3. Springer Nature, pp. 557–566, 2018.","ama":"Harrison M, Jongepier E, Robertson H, et al. Hemimetabolous genomes reveal molecular basis of termite eusociality. <i>Nature Ecology and Evolution</i>. 2018;2(3):557-566. doi:<a href=\"https://doi.org/10.1038/s41559-017-0459-1\">10.1038/s41559-017-0459-1</a>","ista":"Harrison M, Jongepier E, Robertson H, Arning N, Bitard Feildel T, Chao H, Childers C, Dinh H, Doddapaneni H, Dugan S, Gowin J, Greiner C, Han Y, Hu H, Hughes D, Huylmans AK, Kemena K, Kremer L, Lee S, López Ezquerra A, Mallet L, Monroy Kuhn J, Moser A, Murali S, Muzny D, Otani S, Piulachs M, Poelchau M, Qu J, Schaub F, Wada Katsumata A, Worley K, Xie Q, Ylla G, Poulsen M, Gibbs R, Schal C, Richards S, Belles X, Korb J, Bornberg Bauer E. 2018. Hemimetabolous genomes reveal molecular basis of termite eusociality. Nature Ecology and Evolution. 2(3), 557–566.","chicago":"Harrison, Mark, Evelien Jongepier, Hugh Robertson, Nicolas Arning, Tristan Bitard Feildel, Hsu Chao, Christopher Childers, et al. “Hemimetabolous Genomes Reveal Molecular Basis of Termite Eusociality.” <i>Nature Ecology and Evolution</i>. Springer Nature, 2018. <a href=\"https://doi.org/10.1038/s41559-017-0459-1\">https://doi.org/10.1038/s41559-017-0459-1</a>.","short":"M. Harrison, E. Jongepier, H. Robertson, N. Arning, T. Bitard Feildel, H. Chao, C. Childers, H. Dinh, H. Doddapaneni, S. Dugan, J. Gowin, C. Greiner, Y. Han, H. Hu, D. Hughes, A.K. Huylmans, K. Kemena, L. Kremer, S. Lee, A. López Ezquerra, L. Mallet, J. Monroy Kuhn, A. Moser, S. Murali, D. Muzny, S. Otani, M. Piulachs, M. Poelchau, J. Qu, F. Schaub, A. Wada Katsumata, K. Worley, Q. Xie, G. Ylla, M. Poulsen, R. Gibbs, C. Schal, S. Richards, X. Belles, J. Korb, E. Bornberg Bauer, Nature Ecology and Evolution 2 (2018) 557–566.","apa":"Harrison, M., Jongepier, E., Robertson, H., Arning, N., Bitard Feildel, T., Chao, H., … Bornberg Bauer, E. (2018). Hemimetabolous genomes reveal molecular basis of termite eusociality. <i>Nature Ecology and Evolution</i>. Springer Nature. <a href=\"https://doi.org/10.1038/s41559-017-0459-1\">https://doi.org/10.1038/s41559-017-0459-1</a>","mla":"Harrison, Mark, et al. “Hemimetabolous Genomes Reveal Molecular Basis of Termite Eusociality.” <i>Nature Ecology and Evolution</i>, vol. 2, no. 3, Springer Nature, 2018, pp. 557–66, doi:<a href=\"https://doi.org/10.1038/s41559-017-0459-1\">10.1038/s41559-017-0459-1</a>."},"abstract":[{"lang":"eng","text":"Around 150 million years ago, eusocial termites evolved from within the cockroaches, 50 million years before eusocial Hymenoptera, such as bees and ants, appeared. Here, we report the 2-Gb genome of the German cockroach, Blattella germanica, and the 1.3-Gb genome of the drywood termite Cryptotermes secundus. We show evolutionary signatures of termite eusociality by comparing the genomes and transcriptomes of three termites and the cockroach against the background of 16 other eusocial and non-eusocial insects. Dramatic adaptive changes in genes underlying the production and perception of pheromones confirm the importance of chemical communication in the termites. These are accompanied by major changes in gene regulation and the molecular evolution of caste determination. Many of these results parallel molecular mechanisms of eusocial evolution in Hymenoptera. However, the specific solutions are remarkably different, thus revealing a striking case of convergence in one of the major evolutionary transitions in biological complexity."}],"publication_status":"published","_id":"448","related_material":{"record":[{"id":"9841","status":"public","relation":"research_data"}]},"ddc":["576"],"oa":1,"publication":"Nature Ecology and Evolution","title":"Hemimetabolous genomes reveal molecular basis of termite eusociality","page":"557-566","file":[{"date_created":"2018-12-12T10:09:08Z","relation":"main_file","content_type":"application/pdf","creator":"system","file_size":3730583,"date_updated":"2020-07-14T12:46:30Z","file_id":"4731","access_level":"open_access","file_name":"IST-2018-969-v1+1_2018_Huylmans_Hemimetabolous_genomes.pdf","checksum":"874953136ac125e65f37971d3cabc5b7"}],"external_id":{"isi":["000426559600026"]},"date_published":"2018-02-05T00:00:00Z","scopus_import":"1","day":"05","oa_version":"Published Version","type":"journal_article","date_updated":"2023-09-11T14:10:57Z","user_id":"c635000d-4b10-11ee-a964-aac5a93f6ac1","article_processing_charge":"No","acknowledgement":"We thank O. Niehuis for allowing use of the unpublished E. danica genome, J. Gadau and C. Smith for comments and advice on the manuscript, and J. Schmitz for assistance with analyses and proofreading the manuscript. J.K. thanks Charles Darwin University (Australia), especially S. Garnett and the Horticulture and Aquaculture team, for providing logistic support to collect C. secundus. The Parks and Wildlife Commission, Northern Territory, the Department of the Environment, Water, Heritage and the Arts gave permission to collect (Permit number 36401) and export (Permit WT2010-6997) the termites. USDA is an equal opportunity provider and employer. M.C.H. and E.J. are supported by DFG grant BO2544/11-1 to E.B.-B. J.K. is supported by University of Osnabrück and DFG grant KO1895/16-1. X.B. and M.-D.P. are supported by Spanish Ministerio de Economía y Competitividad (CGL2012-36251 and CGL2015-64727-P to X.B., and CGL2016-76011-R to M.-D.P.), including FEDER funds, and by Catalan Government (2014 SGR 619). C.S. is supported by grants from the US Department of Housing and Urban Development (NCHHU-0017-13), the National Science Foundation (IOS-1557864), the Alfred P. Sloan Foundation (2013-5-35 MBE), the National Institute of Environmental Health Sciences (P30ES025128) to the Center for Human Health and the Environment, and the Blanton J. Whitmire Endowment. M.P. is supported by a Villum Kann Rasmussen Young Investigator Fellowship (VKR10101).","has_accepted_license":"1","department":[{"_id":"BeVi"}],"doi":"10.1038/s41559-017-0459-1","language":[{"iso":"eng"}]}]