---
_id: '14356'
abstract:
- lang: eng
  text: Aminoacyl-tRNA synthetases (ARSs) are essential enzymes for faithful assignment
    of amino acids to their cognate tRNA. Variants in ARS genes are frequently associated
    with clinically heterogeneous phenotypes in humans and follow both autosomal dominant
    or recessive inheritance patterns in many instances. Variants in tryptophanyl-tRNA
    synthetase 1 (WARS1) cause autosomal dominantly inherited distal hereditary motor
    neuropathy and Charcot-Marie-Tooth disease. Presently, only one family with biallelic
    WARS1 variants has been described. We present three affected individuals from
    two families with biallelic variants (p.Met1? and p.(Asp419Asn)) in WARS1, showing
    varying severities of developmental delay and intellectual disability. Hearing
    impairment and microcephaly, as well as abnormalities of the brain, skeletal system,
    movement/gait, and behavior were variable features. Phenotyping of knocked down
    wars-1 in a Caenorhabditis elegans model showed depletion is associated with defects
    in germ cell development. A wars1 knockout vertebrate model recapitulates the
    human clinical phenotypes, confirms variant pathogenicity, and uncovers evidence
    implicating the p.Met1? variant as potentially impacting an exon critical for
    normal hearing. Together, our findings provide consolidating evidence for biallelic
    disruption of WARS1 as causal for an autosomal recessive neurodevelopmental syndrome
    and present a vertebrate model that recapitulates key phenotypes observed in patients.
article_processing_charge: No
article_type: original
author:
- first_name: Sheng-Jia
  full_name: Lin, Sheng-Jia
  last_name: Lin
- first_name: Barbara
  full_name: Vona, Barbara
  last_name: Vona
- first_name: Hillary M.
  full_name: Porter, Hillary M.
  last_name: Porter
- first_name: Mahmoud
  full_name: Izadi, Mahmoud
  last_name: Izadi
- first_name: Kevin
  full_name: Huang, Kevin
  id: 3b3d2888-1ff6-11ee-9fa6-8f209ca91fe3
  last_name: Huang
  orcid: 0000-0002-2512-7812
- first_name: Yves
  full_name: Lacassie, Yves
  last_name: Lacassie
- first_name: Jill A.
  full_name: Rosenfeld, Jill A.
  last_name: Rosenfeld
- first_name: Saadullah
  full_name: Khan, Saadullah
  last_name: Khan
- first_name: Cassidy
  full_name: Petree, Cassidy
  last_name: Petree
- first_name: Tayyiba A.
  full_name: Ali, Tayyiba A.
  last_name: Ali
- first_name: Nazif
  full_name: Muhammad, Nazif
  last_name: Muhammad
- first_name: Sher A.
  full_name: Khan, Sher A.
  last_name: Khan
- first_name: Noor
  full_name: Muhammad, Noor
  last_name: Muhammad
- first_name: Pengfei
  full_name: Liu, Pengfei
  last_name: Liu
- first_name: Marie-Louise
  full_name: Haymon, Marie-Louise
  last_name: Haymon
- first_name: Franz
  full_name: Rueschendorf, Franz
  last_name: Rueschendorf
- first_name: Il-Keun
  full_name: Kong, Il-Keun
  last_name: Kong
- first_name: Linda
  full_name: Schnapp, Linda
  last_name: Schnapp
- first_name: Natasha
  full_name: Shur, Natasha
  last_name: Shur
- first_name: Lynn
  full_name: Chorich, Lynn
  last_name: Chorich
- first_name: Lawrence
  full_name: Layman, Lawrence
  last_name: Layman
- first_name: Thomas
  full_name: Haaf, Thomas
  last_name: Haaf
- first_name: Ehsan
  full_name: Pourkarimi, Ehsan
  last_name: Pourkarimi
- first_name: Hyung-Goo
  full_name: Kim, Hyung-Goo
  last_name: Kim
- first_name: Gaurav K.
  full_name: Varshney, Gaurav K.
  last_name: Varshney
citation:
  ama: Lin S-J, Vona B, Porter HM, et al. Biallelic variants in WARS1 cause a highly
    variable neurodevelopmental syndrome and implicate a critical exon for normal
    auditory function. <i>Human Mutation</i>. 2022;43(10):1472-1489. doi:<a href="https://doi.org/10.1002/humu.24435">10.1002/humu.24435</a>
  apa: Lin, S.-J., Vona, B., Porter, H. M., Izadi, M., Huang, K., Lacassie, Y., …
    Varshney, G. K. (2022). Biallelic variants in WARS1 cause a highly variable neurodevelopmental
    syndrome and implicate a critical exon for normal auditory function. <i>Human
    Mutation</i>. Wiley. <a href="https://doi.org/10.1002/humu.24435">https://doi.org/10.1002/humu.24435</a>
  chicago: Lin, Sheng-Jia, Barbara Vona, Hillary M. Porter, Mahmoud Izadi, Kevin Huang,
    Yves Lacassie, Jill A. Rosenfeld, et al. “Biallelic Variants in WARS1 Cause a
    Highly Variable Neurodevelopmental Syndrome and Implicate a Critical Exon for
    Normal Auditory Function.” <i>Human Mutation</i>. Wiley, 2022. <a href="https://doi.org/10.1002/humu.24435">https://doi.org/10.1002/humu.24435</a>.
  ieee: S.-J. Lin <i>et al.</i>, “Biallelic variants in WARS1 cause a highly variable
    neurodevelopmental syndrome and implicate a critical exon for normal auditory
    function,” <i>Human Mutation</i>, vol. 43, no. 10. Wiley, pp. 1472–1489, 2022.
  ista: Lin S-J, Vona B, Porter HM, Izadi M, Huang K, Lacassie Y, Rosenfeld JA, Khan
    S, Petree C, Ali TA, Muhammad N, Khan SA, Muhammad N, Liu P, Haymon M-L, Rueschendorf
    F, Kong I-K, Schnapp L, Shur N, Chorich L, Layman L, Haaf T, Pourkarimi E, Kim
    H-G, Varshney GK. 2022. Biallelic variants in WARS1 cause a highly variable neurodevelopmental
    syndrome and implicate a critical exon for normal auditory function. Human Mutation.
    43(10), 1472–1489.
  mla: Lin, Sheng-Jia, et al. “Biallelic Variants in WARS1 Cause a Highly Variable
    Neurodevelopmental Syndrome and Implicate a Critical Exon for Normal Auditory
    Function.” <i>Human Mutation</i>, vol. 43, no. 10, Wiley, 2022, pp. 1472–89, doi:<a
    href="https://doi.org/10.1002/humu.24435">10.1002/humu.24435</a>.
  short: S.-J. Lin, B. Vona, H.M. Porter, M. Izadi, K. Huang, Y. Lacassie, J.A. Rosenfeld,
    S. Khan, C. Petree, T.A. Ali, N. Muhammad, S.A. Khan, N. Muhammad, P. Liu, M.-L.
    Haymon, F. Rueschendorf, I.-K. Kong, L. Schnapp, N. Shur, L. Chorich, L. Layman,
    T. Haaf, E. Pourkarimi, H.-G. Kim, G.K. Varshney, Human Mutation 43 (2022) 1472–1489.
date_created: 2023-09-20T20:58:24Z
date_published: 2022-10-01T00:00:00Z
date_updated: 2023-09-25T08:54:14Z
day: '01'
ddc:
- '570'
doi: 10.1002/humu.24435
extern: '1'
file:
- access_level: open_access
  checksum: 74b01d4e4084b2f64c30ed32b18ee928
  content_type: application/pdf
  creator: dernst
  date_created: 2023-09-25T08:52:54Z
  date_updated: 2023-09-25T08:52:54Z
  file_id: '14370'
  file_name: 2022_HumanMutation_Lin.pdf
  file_size: 12131312
  relation: main_file
  success: 1
file_date_updated: 2023-09-25T08:52:54Z
has_accepted_license: '1'
intvolume: '        43'
issue: '10'
keyword:
- autosomal recessive
- biallelic variants
- C
- elegans
- translation initiation sites
- tryptophanyl-tRNA synthetase 1 (WARS1)
- WHEP domain
- zebrafish
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
page: 1472-1489
publication: Human Mutation
publication_identifier:
  issn:
  - 1059-7794
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: Biallelic variants in WARS1 cause a highly variable neurodevelopmental syndrome
  and implicate a critical exon for normal auditory function
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 43
year: '2022'
...
---
_id: '14357'
abstract:
- lang: eng
  text: 'Aminoacylation of transfer RNA (tRNA) is a key step in protein biosynthesis,
    carried out by highly specific aminoacyl-tRNA synthetases (ARSs). ARSs have been
    implicated in autosomal dominant and autosomal recessive human disorders. Autosomal
    dominant variants in tryptophanyl-tRNA synthetase 1 (WARS1) are known to cause
    distal hereditary motor neuropathy and Charcot-Marie-Tooth disease, but a recessively
    inherited phenotype is yet to be clearly defined. Seryl-tRNA synthetase 1 (SARS1)
    has rarely been implicated in an autosomal recessive developmental disorder. Here,
    we report five individuals with biallelic missense variants in WARS1 or SARS1,
    who presented with an overlapping phenotype of microcephaly, developmental delay,
    intellectual disability, and brain anomalies. Structural mapping showed that the
    SARS1 variant is located directly within the enzyme’s active site, most likely
    diminishing activity, while the WARS1 variant is located in the N-terminal domain.
    We further characterize the identified WARS1 variant by showing that it negatively
    impacts protein abundance and is unable to rescue the phenotype of a CRISPR/Cas9
    wars1 knockout zebrafish model. In summary, we describe two overlapping autosomal
    recessive syndromes caused by variants in WARS1 and SARS1, present functional
    insights into the pathogenesis of the WARS1-related syndrome and define an emerging
    disease spectrum: ARS-related developmental disorders with or without microcephaly.'
article_processing_charge: No
article_type: original
author:
- first_name: Nina
  full_name: Boegershausen, Nina
  last_name: Boegershausen
- first_name: Hannah E.
  full_name: Krawczyk, Hannah E.
  last_name: Krawczyk
- first_name: Rami A.
  full_name: Jamra, Rami A.
  last_name: Jamra
- first_name: Sheng-Jia
  full_name: Lin, Sheng-Jia
  last_name: Lin
- first_name: Goekhan
  full_name: Yigit, Goekhan
  last_name: Yigit
- first_name: Irina
  full_name: Huening, Irina
  last_name: Huening
- first_name: Anna M.
  full_name: Polo, Anna M.
  last_name: Polo
- first_name: Barbara
  full_name: Vona, Barbara
  last_name: Vona
- first_name: Kevin
  full_name: Huang, Kevin
  id: 3b3d2888-1ff6-11ee-9fa6-8f209ca91fe3
  last_name: Huang
  orcid: 0000-0002-2512-7812
- first_name: Julia
  full_name: Schmidt, Julia
  last_name: Schmidt
- first_name: Janine
  full_name: Altmueller, Janine
  last_name: Altmueller
- first_name: Johannes
  full_name: Luppe, Johannes
  last_name: Luppe
- first_name: Konrad
  full_name: Platzer, Konrad
  last_name: Platzer
- first_name: Beate B.
  full_name: Doergeloh, Beate B.
  last_name: Doergeloh
- first_name: Andreas
  full_name: Busche, Andreas
  last_name: Busche
- first_name: Saskia
  full_name: Biskup, Saskia
  last_name: Biskup
- first_name: Marisa
  full_name: Mendes, I, Marisa
  last_name: Mendes, I
- first_name: Desiree E. C.
  full_name: Smith, Desiree E. C.
  last_name: Smith
- first_name: Gajja S.
  full_name: Salomons, Gajja S.
  last_name: Salomons
- first_name: Arne
  full_name: Zibat, Arne
  last_name: Zibat
- first_name: Eva
  full_name: Bueltmann, Eva
  last_name: Bueltmann
- first_name: Peter
  full_name: Nuernberg, Peter
  last_name: Nuernberg
- first_name: Malte
  full_name: Spielmann, Malte
  last_name: Spielmann
- first_name: Johannes R.
  full_name: Lemke, Johannes R.
  last_name: Lemke
- first_name: Yun
  full_name: Li, Yun
  last_name: Li
- first_name: Martin
  full_name: Zenker, Martin
  last_name: Zenker
- first_name: Gaurav K.
  full_name: Varshney, Gaurav K.
  last_name: Varshney
- first_name: Hauke S.
  full_name: Hillen, Hauke S.
  last_name: Hillen
- first_name: Christian P.
  full_name: Kratz, Christian P.
  last_name: Kratz
- first_name: Bernd
  full_name: Wollnik, Bernd
  last_name: Wollnik
citation:
  ama: 'Boegershausen N, Krawczyk HE, Jamra RA, et al. WARS1 and SARS1: Two tRNA synthetases
    implicated in autosomal recessive microcephaly. <i>Human Mutation</i>. 2022;43(10):1454-1471.
    doi:<a href="https://doi.org/10.1002/humu.24430">10.1002/humu.24430</a>'
  apa: 'Boegershausen, N., Krawczyk, H. E., Jamra, R. A., Lin, S.-J., Yigit, G., Huening,
    I., … Wollnik, B. (2022). WARS1 and SARS1: Two tRNA synthetases implicated in
    autosomal recessive microcephaly. <i>Human Mutation</i>. Wiley. <a href="https://doi.org/10.1002/humu.24430">https://doi.org/10.1002/humu.24430</a>'
  chicago: 'Boegershausen, Nina, Hannah E. Krawczyk, Rami A. Jamra, Sheng-Jia Lin,
    Goekhan Yigit, Irina Huening, Anna M. Polo, et al. “WARS1 and SARS1: Two TRNA
    Synthetases Implicated in Autosomal Recessive Microcephaly.” <i>Human Mutation</i>.
    Wiley, 2022. <a href="https://doi.org/10.1002/humu.24430">https://doi.org/10.1002/humu.24430</a>.'
  ieee: 'N. Boegershausen <i>et al.</i>, “WARS1 and SARS1: Two tRNA synthetases implicated
    in autosomal recessive microcephaly,” <i>Human Mutation</i>, vol. 43, no. 10.
    Wiley, pp. 1454–1471, 2022.'
  ista: 'Boegershausen N, Krawczyk HE, Jamra RA, Lin S-J, Yigit G, Huening I, Polo
    AM, Vona B, Huang K, Schmidt J, Altmueller J, Luppe J, Platzer K, Doergeloh BB,
    Busche A, Biskup S, Mendes, I M, Smith DEC, Salomons GS, Zibat A, Bueltmann E,
    Nuernberg P, Spielmann M, Lemke JR, Li Y, Zenker M, Varshney GK, Hillen HS, Kratz
    CP, Wollnik B. 2022. WARS1 and SARS1: Two tRNA synthetases implicated in autosomal
    recessive microcephaly. Human Mutation. 43(10), 1454–1471.'
  mla: 'Boegershausen, Nina, et al. “WARS1 and SARS1: Two TRNA Synthetases Implicated
    in Autosomal Recessive Microcephaly.” <i>Human Mutation</i>, vol. 43, no. 10,
    Wiley, 2022, pp. 1454–71, doi:<a href="https://doi.org/10.1002/humu.24430">10.1002/humu.24430</a>.'
  short: N. Boegershausen, H.E. Krawczyk, R.A. Jamra, S.-J. Lin, G. Yigit, I. Huening,
    A.M. Polo, B. Vona, K. Huang, J. Schmidt, J. Altmueller, J. Luppe, K. Platzer,
    B.B. Doergeloh, A. Busche, S. Biskup, M. Mendes, I, D.E.C. Smith, G.S. Salomons,
    A. Zibat, E. Bueltmann, P. Nuernberg, M. Spielmann, J.R. Lemke, Y. Li, M. Zenker,
    G.K. Varshney, H.S. Hillen, C.P. Kratz, B. Wollnik, Human Mutation 43 (2022) 1454–1471.
date_created: 2023-09-20T20:59:33Z
date_published: 2022-10-01T00:00:00Z
date_updated: 2023-09-25T08:43:06Z
day: '01'
ddc:
- '570'
doi: 10.1002/humu.24430
extern: '1'
external_id:
  pmid:
  - '35790048'
file:
- access_level: open_access
  checksum: c31fc91e0445c35b9da83eb911a9b552
  content_type: application/pdf
  creator: dernst
  date_created: 2023-09-25T08:41:23Z
  date_updated: 2023-09-25T08:41:23Z
  file_id: '14367'
  file_name: 2022_HumanMutation_Boegershausen.pdf
  file_size: 4863605
  relation: main_file
  success: 1
file_date_updated: 2023-09-25T08:41:23Z
has_accepted_license: '1'
intvolume: '        43'
issue: '10'
keyword:
- aminoacylation
- aminoacyl-tRNA synthetase
- ARS
- CRISPR
- Cas9
- intellectual disability
- microcephaly
- SARS1
- tRNA
- WARS1
- zebrafish
language:
- iso: eng
month: '10'
oa: 1
oa_version: Published Version
page: 1454-1471
pmid: 1
publication: Human Mutation
publication_identifier:
  issn:
  - 1059-7794
publication_status: published
publisher: Wiley
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'WARS1 and SARS1: Two tRNA synthetases implicated in autosomal recessive microcephaly'
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 43
year: '2022'
...
---
_id: '14381'
abstract:
- lang: eng
  text: Expander graphs (sparse but highly connected graphs) have, since their inception,
    been the source of deep links between Mathematics and Computer Science as well
    as applications to other areas. In recent years, a fascinating theory of high-dimensional
    expanders has begun to emerge, which is still in a formative stage but has nonetheless
    already lead to a number of striking results. Unlike for graphs, in higher dimensions
    there is a rich array of non-equivalent notions of expansion (coboundary expansion,
    cosystolic expansion, topological expansion, spectral expansion, etc.), with differents
    strengths and applications. In this talk, we will survey this landscape of high-dimensional
    expansion, with a focus on two main results. First, we will present Gromov’s Topological
    Overlap Theorem, which asserts that coboundary expansion (a quantitative version
    of vanishing mod 2 cohomology) implies topological expansion (roughly, the property
    that for every map from a simplicial complex to a manifold of the same dimension,
    the images of a positive fraction of the simplices have a point in common). Second,
    we will outline a construction of bounded degree 2-dimensional topological expanders,
    due to Kaufman, Kazhdan, and Lubotzky.
article_processing_charge: No
article_type: original
author:
- first_name: Uli
  full_name: Wagner, Uli
  id: 36690CA2-F248-11E8-B48F-1D18A9856A87
  last_name: Wagner
  orcid: 0000-0002-1494-0568
citation:
  ama: Wagner U. High-dimensional expanders (after Gromov, Kaufman, Kazhdan, Lubotzky,
    and others). <i>Bulletin de la Societe Mathematique de France</i>. 2022;438:281-294.
    doi:<a href="https://doi.org/10.24033/ast.1188">10.24033/ast.1188</a>
  apa: Wagner, U. (2022). High-dimensional expanders (after Gromov, Kaufman, Kazhdan,
    Lubotzky, and others). <i>Bulletin de La Societe Mathematique de France</i>. Societe
    Mathematique de France. <a href="https://doi.org/10.24033/ast.1188">https://doi.org/10.24033/ast.1188</a>
  chicago: Wagner, Uli. “High-Dimensional Expanders (after Gromov, Kaufman, Kazhdan,
    Lubotzky, and Others).” <i>Bulletin de La Societe Mathematique de France</i>.
    Societe Mathematique de France, 2022. <a href="https://doi.org/10.24033/ast.1188">https://doi.org/10.24033/ast.1188</a>.
  ieee: U. Wagner, “High-dimensional expanders (after Gromov, Kaufman, Kazhdan, Lubotzky,
    and others),” <i>Bulletin de la Societe Mathematique de France</i>, vol. 438.
    Societe Mathematique de France, pp. 281–294, 2022.
  ista: Wagner U. 2022. High-dimensional expanders (after Gromov, Kaufman, Kazhdan,
    Lubotzky, and others). Bulletin de la Societe Mathematique de France. 438, 281–294.
  mla: Wagner, Uli. “High-Dimensional Expanders (after Gromov, Kaufman, Kazhdan, Lubotzky,
    and Others).” <i>Bulletin de La Societe Mathematique de France</i>, vol. 438,
    Societe Mathematique de France, 2022, pp. 281–94, doi:<a href="https://doi.org/10.24033/ast.1188">10.24033/ast.1188</a>.
  short: U. Wagner, Bulletin de La Societe Mathematique de France 438 (2022) 281–294.
date_created: 2023-10-01T22:01:14Z
date_published: 2022-01-01T00:00:00Z
date_updated: 2023-10-03T08:04:03Z
day: '01'
department:
- _id: UlWa
doi: 10.24033/ast.1188
intvolume: '       438'
language:
- iso: eng
month: '01'
oa_version: None
page: 281-294
publication: Bulletin de la Societe Mathematique de France
publication_identifier:
  eissn:
  - 2102-622X
  issn:
  - 0037-9484
publication_status: published
publisher: Societe Mathematique de France
quality_controlled: '1'
scopus_import: '1'
status: public
title: High-dimensional expanders (after Gromov, Kaufman, Kazhdan, Lubotzky, and others)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 438
year: '2022'
...
---
_id: '14437'
abstract:
- lang: eng
  text: Future LEDs could be based on lead halide perovskites. A breakthrough in preparing
    device-compatible solids composed of nanoscale perovskite crystals overcomes a
    long-standing hurdle in making blue perovskite LEDs.
article_processing_charge: No
article_type: letter_note
author:
- first_name: Hendrik
  full_name: Utzat, Hendrik
  last_name: Utzat
- first_name: Maria
  full_name: Ibáñez, Maria
  id: 43C61214-F248-11E8-B48F-1D18A9856A87
  last_name: Ibáñez
  orcid: 0000-0001-5013-2843
citation:
  ama: Utzat H, Ibáñez M. Molecular engineering enables bright blue LEDs. <i>Nature</i>.
    2022;612(7941):638-639. doi:<a href="https://doi.org/10.1038/d41586-022-04447-0">10.1038/d41586-022-04447-0</a>
  apa: Utzat, H., &#38; Ibáñez, M. (2022). Molecular engineering enables bright blue
    LEDs. <i>Nature</i>. Springer Nature. <a href="https://doi.org/10.1038/d41586-022-04447-0">https://doi.org/10.1038/d41586-022-04447-0</a>
  chicago: Utzat, Hendrik, and Maria Ibáñez. “Molecular Engineering Enables Bright
    Blue LEDs.” <i>Nature</i>. Springer Nature, 2022. <a href="https://doi.org/10.1038/d41586-022-04447-0">https://doi.org/10.1038/d41586-022-04447-0</a>.
  ieee: H. Utzat and M. Ibáñez, “Molecular engineering enables bright blue LEDs,”
    <i>Nature</i>, vol. 612, no. 7941. Springer Nature, pp. 638–639, 2022.
  ista: Utzat H, Ibáñez M. 2022. Molecular engineering enables bright blue LEDs. Nature.
    612(7941), 638–639.
  mla: Utzat, Hendrik, and Maria Ibáñez. “Molecular Engineering Enables Bright Blue
    LEDs.” <i>Nature</i>, vol. 612, no. 7941, Springer Nature, 2022, pp. 638–39, doi:<a
    href="https://doi.org/10.1038/d41586-022-04447-0">10.1038/d41586-022-04447-0</a>.
  short: H. Utzat, M. Ibáñez, Nature 612 (2022) 638–639.
date_created: 2023-10-17T11:14:43Z
date_published: 2022-12-21T00:00:00Z
date_updated: 2023-10-18T06:26:30Z
day: '21'
department:
- _id: MaIb
doi: 10.1038/d41586-022-04447-0
external_id:
  pmid:
  - '36543947'
intvolume: '       612'
issue: '7941'
keyword:
- Multidisciplinary
language:
- iso: eng
month: '12'
oa_version: None
page: 638-639
pmid: 1
publication: Nature
publication_identifier:
  eissn:
  - 1476-4687
  issn:
  - 0028-0836
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: Molecular engineering enables bright blue LEDs
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 612
year: '2022'
...
---
_id: '14520'
abstract:
- lang: eng
  text: 'This dataset comprises all data shown in the figures of the submitted article
    "Compact vacuum gap transmon qubits: Selective and sensitive probes for superconductor
    surface losses" at arxiv.org/abs/2206.14104. Additional raw data are available
    from the corresponding author on reasonable request.'
article_processing_charge: No
author:
- first_name: Martin
  full_name: Zemlicka, Martin
  id: 2DCF8DE6-F248-11E8-B48F-1D18A9856A87
  last_name: Zemlicka
- first_name: Elena
  full_name: Redchenko, Elena
  id: 2C21D6E8-F248-11E8-B48F-1D18A9856A87
  last_name: Redchenko
- first_name: Matilda
  full_name: Peruzzo, Matilda
  id: 3F920B30-F248-11E8-B48F-1D18A9856A87
  last_name: Peruzzo
  orcid: 0000-0002-3415-4628
- first_name: Farid
  full_name: Hassani, Farid
  id: 2AED110C-F248-11E8-B48F-1D18A9856A87
  last_name: Hassani
  orcid: 0000-0001-6937-5773
- first_name: Andrea
  full_name: Trioni, Andrea
  id: 42F71B44-F248-11E8-B48F-1D18A9856A87
  last_name: Trioni
- first_name: Shabir
  full_name: Barzanjeh, Shabir
  id: 2D25E1F6-F248-11E8-B48F-1D18A9856A87
  last_name: Barzanjeh
  orcid: 0000-0003-0415-1423
- first_name: Johannes M
  full_name: Fink, Johannes M
  id: 4B591CBA-F248-11E8-B48F-1D18A9856A87
  last_name: Fink
  orcid: 0000-0001-8112-028X
citation:
  ama: 'Zemlicka M, Redchenko E, Peruzzo M, et al. Compact vacuum gap transmon qubits:
    Selective and sensitive probes for superconductor surface losses. 2022. doi:<a
    href="https://doi.org/10.5281/ZENODO.8408897">10.5281/ZENODO.8408897</a>'
  apa: 'Zemlicka, M., Redchenko, E., Peruzzo, M., Hassani, F., Trioni, A., Barzanjeh,
    S., &#38; Fink, J. M. (2022). Compact vacuum gap transmon qubits: Selective and
    sensitive probes for superconductor surface losses. Zenodo. <a href="https://doi.org/10.5281/ZENODO.8408897">https://doi.org/10.5281/ZENODO.8408897</a>'
  chicago: 'Zemlicka, Martin, Elena Redchenko, Matilda Peruzzo, Farid Hassani, Andrea
    Trioni, Shabir Barzanjeh, and Johannes M Fink. “Compact Vacuum Gap Transmon Qubits:
    Selective and Sensitive Probes for Superconductor Surface Losses.” Zenodo, 2022.
    <a href="https://doi.org/10.5281/ZENODO.8408897">https://doi.org/10.5281/ZENODO.8408897</a>.'
  ieee: 'M. Zemlicka <i>et al.</i>, “Compact vacuum gap transmon qubits: Selective
    and sensitive probes for superconductor surface losses.” Zenodo, 2022.'
  ista: 'Zemlicka M, Redchenko E, Peruzzo M, Hassani F, Trioni A, Barzanjeh S, Fink
    JM. 2022. Compact vacuum gap transmon qubits: Selective and sensitive probes for
    superconductor surface losses, Zenodo, <a href="https://doi.org/10.5281/ZENODO.8408897">10.5281/ZENODO.8408897</a>.'
  mla: 'Zemlicka, Martin, et al. <i>Compact Vacuum Gap Transmon Qubits: Selective
    and Sensitive Probes for Superconductor Surface Losses</i>. Zenodo, 2022, doi:<a
    href="https://doi.org/10.5281/ZENODO.8408897">10.5281/ZENODO.8408897</a>.'
  short: M. Zemlicka, E. Redchenko, M. Peruzzo, F. Hassani, A. Trioni, S. Barzanjeh,
    J.M. Fink, (2022).
date_created: 2023-11-13T08:09:10Z
date_published: 2022-06-28T00:00:00Z
date_updated: 2024-09-10T12:23:57Z
day: '28'
ddc:
- '530'
department:
- _id: JoFi
doi: 10.5281/ZENODO.8408897
has_accepted_license: '1'
main_file_link:
- open_access: '1'
  url: https://doi.org/10.5281/ZENODO.8408897
month: '06'
oa: 1
oa_version: Published Version
publisher: Zenodo
related_material:
  record:
  - id: '14517'
    relation: used_in_publication
    status: public
status: public
title: 'Compact vacuum gap transmon qubits: Selective and sensitive probes for superconductor
  surface losses'
tmp:
  image: /images/cc_0.png
  legal_code_url: https://creativecommons.org/publicdomain/zero/1.0/legalcode
  name: Creative Commons Public Domain Dedication (CC0 1.0)
  short: CC0 (1.0)
type: research_data_reference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2022'
...
---
_id: '14597'
abstract:
- lang: eng
  text: "Phase-field models such as the Allen-Cahn equation may give rise to the formation
    and evolution of geometric shapes, a phenomenon that may be analyzed rigorously
    in suitable scaling regimes. In its sharp-interface limit, the vectorial Allen-Cahn
    equation with a potential with N≥3 distinct minima has been conjectured to describe
    the evolution of branched interfaces by multiphase mean curvature flow.\r\nIn
    the present work, we give a rigorous proof for this statement in two and three
    ambient dimensions and for a suitable class of potentials: As long as a strong
    solution to multiphase mean curvature flow exists, solutions to the vectorial
    Allen-Cahn equation with well-prepared initial data converge towards multiphase
    mean curvature flow in the limit of vanishing interface width parameter ε↘0. We
    even establish the rate of convergence O(ε1/2).\r\nOur approach is based on the
    gradient flow structure of the Allen-Cahn equation and its limiting motion: Building
    on the recent concept of \"gradient flow calibrations\" for multiphase mean curvature
    flow, we introduce a notion of relative entropy for the vectorial Allen-Cahn equation
    with multi-well potential. This enables us to overcome the limitations of other
    approaches, e.g. avoiding the need for a stability analysis of the Allen-Cahn
    operator or additional convergence hypotheses for the energy at positive times."
article_processing_charge: No
arxiv: 1
author:
- first_name: Julian L
  full_name: Fischer, Julian L
  id: 2C12A0B0-F248-11E8-B48F-1D18A9856A87
  last_name: Fischer
  orcid: 0000-0002-0479-558X
- first_name: Alice
  full_name: Marveggio, Alice
  id: 25647992-AA84-11E9-9D75-8427E6697425
  last_name: Marveggio
citation:
  ama: Fischer JL, Marveggio A. Quantitative convergence of the vectorial Allen-Cahn
    equation towards multiphase mean curvature flow. <i>arXiv</i>. doi:<a href="https://doi.org/10.48550/ARXIV.2203.17143">10.48550/ARXIV.2203.17143</a>
  apa: Fischer, J. L., &#38; Marveggio, A. (n.d.). Quantitative convergence of the
    vectorial Allen-Cahn equation towards multiphase mean curvature flow. <i>arXiv</i>.
    <a href="https://doi.org/10.48550/ARXIV.2203.17143">https://doi.org/10.48550/ARXIV.2203.17143</a>
  chicago: Fischer, Julian L, and Alice Marveggio. “Quantitative Convergence of the
    Vectorial Allen-Cahn Equation towards Multiphase Mean Curvature Flow.” <i>ArXiv</i>,
    n.d. <a href="https://doi.org/10.48550/ARXIV.2203.17143">https://doi.org/10.48550/ARXIV.2203.17143</a>.
  ieee: J. L. Fischer and A. Marveggio, “Quantitative convergence of the vectorial
    Allen-Cahn equation towards multiphase mean curvature flow,” <i>arXiv</i>. .
  ista: Fischer JL, Marveggio A. Quantitative convergence of the vectorial Allen-Cahn
    equation towards multiphase mean curvature flow. arXiv, <a href="https://doi.org/10.48550/ARXIV.2203.17143">10.48550/ARXIV.2203.17143</a>.
  mla: Fischer, Julian L., and Alice Marveggio. “Quantitative Convergence of the Vectorial
    Allen-Cahn Equation towards Multiphase Mean Curvature Flow.” <i>ArXiv</i>, doi:<a
    href="https://doi.org/10.48550/ARXIV.2203.17143">10.48550/ARXIV.2203.17143</a>.
  short: J.L. Fischer, A. Marveggio, ArXiv (n.d.).
date_created: 2023-11-23T09:30:02Z
date_published: 2022-03-31T00:00:00Z
date_updated: 2023-11-30T13:25:02Z
day: '31'
department:
- _id: JuFi
doi: 10.48550/ARXIV.2203.17143
ec_funded: 1
external_id:
  arxiv:
  - '2203.17143'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/2203.17143
month: '03'
oa: 1
oa_version: Preprint
project:
- _id: 0aa76401-070f-11eb-9043-b5bb049fa26d
  call_identifier: H2020
  grant_number: '948819'
  name: Bridging Scales in Random Materials
publication: arXiv
publication_status: submitted
related_material:
  record:
  - id: '14587'
    relation: dissertation_contains
    status: public
status: public
title: Quantitative convergence of the vectorial Allen-Cahn equation towards multiphase
  mean curvature flow
type: preprint
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2022'
...
---
_id: '14600'
abstract:
- lang: eng
  text: We study the problem of learning controllers for discrete-time non-linear
    stochastic dynamical systems with formal reach-avoid guarantees. This work presents
    the first method for providing formal reach-avoid guarantees, which combine and
    generalize stability and safety guarantees, with a tolerable probability threshold
    $p\in[0,1]$ over the infinite time horizon. Our method leverages advances in machine
    learning literature and it represents formal certificates as neural networks.
    In particular, we learn a certificate in the form of a reach-avoid supermartingale
    (RASM), a novel notion that we introduce in this work. Our RASMs provide reachability
    and avoidance guarantees by imposing constraints on what can be viewed as a stochastic
    extension of level sets of Lyapunov functions for deterministic systems. Our approach
    solves several important problems -- it can be used to learn a control policy
    from scratch, to verify a reach-avoid specification for a fixed control policy,
    or to fine-tune a pre-trained policy if it does not satisfy the reach-avoid specification.
    We validate our approach on $3$ stochastic non-linear reinforcement learning tasks.
article_processing_charge: No
arxiv: 1
author:
- first_name: Dorde
  full_name: Zikelic, Dorde
  id: 294AA7A6-F248-11E8-B48F-1D18A9856A87
  last_name: Zikelic
  orcid: 0000-0002-4681-1699
- first_name: Mathias
  full_name: Lechner, Mathias
  id: 3DC22916-F248-11E8-B48F-1D18A9856A87
  last_name: Lechner
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000-0002-2985-7724
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
citation:
  ama: Zikelic D, Lechner M, Henzinger TA, Chatterjee K. Learning control policies
    for stochastic systems with reach-avoid guarantees. <i>arXiv</i>. doi:<a href="https://doi.org/10.48550/ARXIV.2210.05308">10.48550/ARXIV.2210.05308</a>
  apa: Zikelic, D., Lechner, M., Henzinger, T. A., &#38; Chatterjee, K. (n.d.). Learning
    control policies for stochastic systems with reach-avoid guarantees. <i>arXiv</i>.
    <a href="https://doi.org/10.48550/ARXIV.2210.05308">https://doi.org/10.48550/ARXIV.2210.05308</a>
  chicago: Zikelic, Dorde, Mathias Lechner, Thomas A Henzinger, and Krishnendu Chatterjee.
    “Learning Control Policies for Stochastic Systems with Reach-Avoid Guarantees.”
    <i>ArXiv</i>, n.d. <a href="https://doi.org/10.48550/ARXIV.2210.05308">https://doi.org/10.48550/ARXIV.2210.05308</a>.
  ieee: D. Zikelic, M. Lechner, T. A. Henzinger, and K. Chatterjee, “Learning control
    policies for stochastic systems with reach-avoid guarantees,” <i>arXiv</i>. .
  ista: Zikelic D, Lechner M, Henzinger TA, Chatterjee K. Learning control policies
    for stochastic systems with reach-avoid guarantees. arXiv, <a href="https://doi.org/10.48550/ARXIV.2210.05308">10.48550/ARXIV.2210.05308</a>.
  mla: Zikelic, Dorde, et al. “Learning Control Policies for Stochastic Systems with
    Reach-Avoid Guarantees.” <i>ArXiv</i>, doi:<a href="https://doi.org/10.48550/ARXIV.2210.05308">10.48550/ARXIV.2210.05308</a>.
  short: D. Zikelic, M. Lechner, T.A. Henzinger, K. Chatterjee, ArXiv (n.d.).
date_created: 2023-11-24T13:10:09Z
date_published: 2022-11-29T00:00:00Z
date_updated: 2025-07-14T09:10:02Z
day: '29'
department:
- _id: KrCh
- _id: ToHe
doi: 10.48550/ARXIV.2210.05308
ec_funded: 1
external_id:
  arxiv:
  - '2210.05308'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-sa/4.0/
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/2210.05308
month: '11'
oa: 1
oa_version: Preprint
project:
- _id: 0599E47C-7A3F-11EA-A408-12923DDC885E
  call_identifier: H2020
  grant_number: '863818'
  name: 'Formal Methods for Stochastic Models: Algorithms and Applications'
- _id: 62781420-2b32-11ec-9570-8d9b63373d4d
  call_identifier: H2020
  grant_number: '101020093'
  name: Vigilant Algorithmic Monitoring of Software
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '665385'
  name: International IST Doctoral Program
publication: arXiv
publication_status: submitted
related_material:
  record:
  - id: '14539'
    relation: dissertation_contains
    status: public
  - id: '14830'
    relation: later_version
    status: public
status: public
title: Learning control policies for stochastic systems with reach-avoid guarantees
tmp:
  image: /images/cc_by_sa.png
  legal_code_url: https://creativecommons.org/licenses/by-sa/4.0/legalcode
  name: Creative Commons Attribution-ShareAlike 4.0 International Public License (CC
    BY-SA 4.0)
  short: CC BY-SA (4.0)
type: preprint
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2022'
...
---
_id: '14601'
abstract:
- lang: eng
  text: "In this work, we address the problem of learning provably stable neural\r\nnetwork
    policies for stochastic control systems. While recent work has\r\ndemonstrated
    the feasibility of certifying given policies using martingale\r\ntheory, the problem
    of how to learn such policies is little explored. Here, we\r\nstudy the effectiveness
    of jointly learning a policy together with a martingale\r\ncertificate that proves
    its stability using a single learning algorithm. We\r\nobserve that the joint
    optimization problem becomes easily stuck in local\r\nminima when starting from
    a randomly initialized policy. Our results suggest\r\nthat some form of pre-training
    of the policy is required for the joint\r\noptimization to repair and verify the
    policy successfully."
article_processing_charge: No
arxiv: 1
author:
- first_name: Dorde
  full_name: Zikelic, Dorde
  id: 294AA7A6-F248-11E8-B48F-1D18A9856A87
  last_name: Zikelic
  orcid: 0000-0002-4681-1699
- first_name: Mathias
  full_name: Lechner, Mathias
  id: 3DC22916-F248-11E8-B48F-1D18A9856A87
  last_name: Lechner
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000-0002-2985-7724
citation:
  ama: Zikelic D, Lechner M, Chatterjee K, Henzinger TA. Learning stabilizing policies
    in stochastic control systems. <i>arXiv</i>. doi:<a href="https://doi.org/10.48550/arXiv.2205.11991">10.48550/arXiv.2205.11991</a>
  apa: Zikelic, D., Lechner, M., Chatterjee, K., &#38; Henzinger, T. A. (n.d.). Learning
    stabilizing policies in stochastic control systems. <i>arXiv</i>. <a href="https://doi.org/10.48550/arXiv.2205.11991">https://doi.org/10.48550/arXiv.2205.11991</a>
  chicago: Zikelic, Dorde, Mathias Lechner, Krishnendu Chatterjee, and Thomas A Henzinger.
    “Learning Stabilizing Policies in Stochastic Control Systems.” <i>ArXiv</i>, n.d.
    <a href="https://doi.org/10.48550/arXiv.2205.11991">https://doi.org/10.48550/arXiv.2205.11991</a>.
  ieee: D. Zikelic, M. Lechner, K. Chatterjee, and T. A. Henzinger, “Learning stabilizing
    policies in stochastic control systems,” <i>arXiv</i>. .
  ista: Zikelic D, Lechner M, Chatterjee K, Henzinger TA. Learning stabilizing policies
    in stochastic control systems. arXiv, <a href="https://doi.org/10.48550/arXiv.2205.11991">10.48550/arXiv.2205.11991</a>.
  mla: Zikelic, Dorde, et al. “Learning Stabilizing Policies in Stochastic Control
    Systems.” <i>ArXiv</i>, doi:<a href="https://doi.org/10.48550/arXiv.2205.11991">10.48550/arXiv.2205.11991</a>.
  short: D. Zikelic, M. Lechner, K. Chatterjee, T.A. Henzinger, ArXiv (n.d.).
date_created: 2023-11-24T13:22:30Z
date_published: 2022-05-24T00:00:00Z
date_updated: 2025-07-14T09:10:00Z
day: '24'
department:
- _id: KrCh
- _id: ToHe
doi: 10.48550/arXiv.2205.11991
ec_funded: 1
external_id:
  arxiv:
  - '2205.11991'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/2205.11991
month: '05'
oa: 1
oa_version: Preprint
project:
- _id: 62781420-2b32-11ec-9570-8d9b63373d4d
  call_identifier: H2020
  grant_number: '101020093'
  name: Vigilant Algorithmic Monitoring of Software
- _id: 0599E47C-7A3F-11EA-A408-12923DDC885E
  call_identifier: H2020
  grant_number: '863818'
  name: 'Formal Methods for Stochastic Models: Algorithms and Applications'
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '665385'
  name: International IST Doctoral Program
publication: arXiv
publication_status: submitted
related_material:
  record:
  - id: '14539'
    relation: dissertation_contains
    status: public
status: public
title: Learning stabilizing policies in stochastic control systems
type: preprint
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2022'
...
---
_id: '10016'
abstract:
- lang: eng
  text: 'Auxin has always been at the forefront of research in plant physiology and
    development. Since the earliest contemplations by Julius von Sachs and Charles
    Darwin, more than a century-long struggle has been waged to understand its function.
    This largely reflects the failures, successes, and inevitable progress in the
    entire field of plant signaling and development. Here I present 14 stations on
    our long and sometimes mystical journey to understand auxin. These highlights
    were selected to give a flavor of the field and to show the scope and limits of
    our current knowledge. A special focus is put on features that make auxin unique
    among phytohormones, such as its dynamic, directional transport network, which
    integrates external and internal signals, including self-organizing feedback.
    Accented are persistent mysteries and controversies. The unexpected discoveries
    related to rapid auxin responses and growth regulation recently disturbed our
    contentment regarding understanding of the auxin signaling mechanism. These new
    revelations, along with advances in technology, usher us into a new, exciting
    era in auxin research. '
acknowledgement: "The author thanks the whole community of researchers consciously
  or unconsciously working on questions related to auxin, whose hard work and enthusiasm
  contributed to development of this exciting story. Particular thanks go to many\r\nbrilliant
  present and past members of the Friml group and our numerous excellent collaborators,
  without whom my own personal journey would not be possible. The way of the cross
  with its 14 stations is a popular devotion among Roman Catholics and inspires them
  to make a spiritual pilgrimage through contemplation of Christ on his last day.
  Its aspects of gradual progress, struggle, passion, and revelation served as an
  inspiration for the formal depiction of our journey to understanding auxin as described
  in this review. It is in no way intended to reflect the personal beliefs of the
  author and readers. I am grateful to Nick Barton, Eva Benková, Lenka Caisová, Matyáš
  Fendrych, Lukáš Fiedler, Monika Frátriková, Jarmila Frimlová, Michelle Gallei, Jakub
  Hajný, Lukas Hoermayer, Alexandra Mally, Ondrˇej Novák, Jan Petrášek, Aleš Pěnčík,
  Steffen Vanneste, Tongda Xu, and Zhenbiao Yang for their valuable comments. Special
  thanks go to Michelle Gallei for her invaluable assistance with the figures."
article_number: a039859
article_processing_charge: No
article_type: review
author:
- first_name: Jiří
  full_name: Friml, Jiří
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
citation:
  ama: Friml J. Fourteen stations of auxin. <i>Cold Spring Harbor Perspectives in
    Biology</i>. 2022;14(5). doi:<a href="https://doi.org/10.1101/cshperspect.a039859
    ">10.1101/cshperspect.a039859 </a>
  apa: Friml, J. (2022). Fourteen stations of auxin. <i>Cold Spring Harbor Perspectives
    in Biology</i>. Cold Spring Harbor Laboratory. <a href="https://doi.org/10.1101/cshperspect.a039859
    ">https://doi.org/10.1101/cshperspect.a039859 </a>
  chicago: Friml, Jiří. “Fourteen Stations of Auxin.” <i>Cold Spring Harbor Perspectives
    in Biology</i>. Cold Spring Harbor Laboratory, 2022. <a href="https://doi.org/10.1101/cshperspect.a039859
    ">https://doi.org/10.1101/cshperspect.a039859 </a>.
  ieee: J. Friml, “Fourteen stations of auxin,” <i>Cold Spring Harbor Perspectives
    in Biology</i>, vol. 14, no. 5. Cold Spring Harbor Laboratory, 2022.
  ista: Friml J. 2022. Fourteen stations of auxin. Cold Spring Harbor Perspectives
    in Biology. 14(5), a039859.
  mla: Friml, Jiří. “Fourteen Stations of Auxin.” <i>Cold Spring Harbor Perspectives
    in Biology</i>, vol. 14, no. 5, a039859, Cold Spring Harbor Laboratory, 2022,
    doi:<a href="https://doi.org/10.1101/cshperspect.a039859 ">10.1101/cshperspect.a039859
    </a>.
  short: J. Friml, Cold Spring Harbor Perspectives in Biology 14 (2022).
date_created: 2021-09-14T11:36:53Z
date_published: 2022-05-27T00:00:00Z
date_updated: 2023-08-02T06:54:42Z
day: '27'
department:
- _id: JiFr
doi: '10.1101/cshperspect.a039859 '
external_id:
  isi:
  - '000806563000003'
  pmid:
  - '34400554'
intvolume: '        14'
isi: 1
issue: '5'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: 'https://doi.org/10.1101/cshperspect.a039859 '
month: '05'
oa: 1
oa_version: Published Version
pmid: 1
publication: Cold Spring Harbor Perspectives in Biology
publication_identifier:
  issn:
  - 1943-0264
publication_status: published
publisher: Cold Spring Harbor Laboratory
quality_controlled: '1'
scopus_import: '1'
status: public
title: Fourteen stations of auxin
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 14
year: '2022'
...
---
_id: '10018'
abstract:
- lang: eng
  text: In order to study integral points of bounded log-anticanonical height on weak
    del Pezzo surfaces, we classify weak del Pezzo pairs. As a representative example,
    we consider a quartic del Pezzo surface of singularity type A1 + A3 and prove
    an analogue of Manin's conjecture for integral points with respect to its singularities
    and its lines.
acknowledgement: The first author was partly supported by grant DE 1646/4-2 of the
  Deutsche Forschungsgemeinschaft. The second author was partly supported by FWF grant
  P 32428-N35 and conducted part of this work as a guest at the Institut de Mathématiques
  de Jussieu–Paris Rive Gauche invited by Antoine Chambert-Loir and funded by DAAD.
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Ulrich
  full_name: Derenthal, Ulrich
  last_name: Derenthal
- first_name: Florian Alexander
  full_name: Wilsch, Florian Alexander
  id: 560601DA-8D36-11E9-A136-7AC1E5697425
  last_name: Wilsch
  orcid: 0000-0001-7302-8256
citation:
  ama: Derenthal U, Wilsch FA. Integral points on singular del Pezzo surfaces. <i>Journal
    of the Institute of Mathematics of Jussieu</i>. 2022. doi:<a href="https://doi.org/10.1017/S1474748022000482">10.1017/S1474748022000482</a>
  apa: Derenthal, U., &#38; Wilsch, F. A. (2022). Integral points on singular del
    Pezzo surfaces. <i>Journal of the Institute of Mathematics of Jussieu</i>. Cambridge
    University Press. <a href="https://doi.org/10.1017/S1474748022000482">https://doi.org/10.1017/S1474748022000482</a>
  chicago: Derenthal, Ulrich, and Florian Alexander Wilsch. “Integral Points on Singular
    Del Pezzo Surfaces.” <i>Journal of the Institute of Mathematics of Jussieu</i>.
    Cambridge University Press, 2022. <a href="https://doi.org/10.1017/S1474748022000482">https://doi.org/10.1017/S1474748022000482</a>.
  ieee: U. Derenthal and F. A. Wilsch, “Integral points on singular del Pezzo surfaces,”
    <i>Journal of the Institute of Mathematics of Jussieu</i>. Cambridge University
    Press, 2022.
  ista: Derenthal U, Wilsch FA. 2022. Integral points on singular del Pezzo surfaces.
    Journal of the Institute of Mathematics of Jussieu.
  mla: Derenthal, Ulrich, and Florian Alexander Wilsch. “Integral Points on Singular
    Del Pezzo Surfaces.” <i>Journal of the Institute of Mathematics of Jussieu</i>,
    Cambridge University Press, 2022, doi:<a href="https://doi.org/10.1017/S1474748022000482">10.1017/S1474748022000482</a>.
  short: U. Derenthal, F.A. Wilsch, Journal of the Institute of Mathematics of Jussieu
    (2022).
date_created: 2021-09-15T10:06:48Z
date_published: 2022-11-10T00:00:00Z
date_updated: 2023-08-02T06:55:10Z
day: '10'
department:
- _id: TiBr
doi: 10.1017/S1474748022000482
external_id:
  arxiv:
  - '2109.06778'
  isi:
  - '000881319200001'
isi: 1
keyword:
- Integral points
- del Pezzo surface
- universal torsor
- Manin’s conjecture
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1017/S1474748022000482
month: '11'
oa: 1
oa_version: Published Version
project:
- _id: 26AEDAB2-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: P32428
  name: New frontiers of the Manin conjecture
publication: Journal of the Institute of Mathematics of Jussieu
publication_identifier:
  eissn:
  - '1475-3030 '
  issn:
  - 1474-7480
publication_status: epub_ahead
publisher: Cambridge University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Integral points on singular del Pezzo surfaces
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
year: '2022'
...
---
_id: '10042'
abstract:
- lang: eng
  text: SnSe has emerged as one of the most promising materials for thermoelectric
    energy conversion due to its extraordinary performance in its single-crystal form
    and its low-cost constituent elements. However, to achieve an economic impact,
    the polycrystalline counterpart needs to replicate the performance of the single
    crystal. Herein, we optimize the thermoelectric performance of polycrystalline
    SnSe produced by consolidating solution-processed and surface-engineered SnSe
    particles. In particular, the SnSe particles are coated with CdSe molecular complexes
    that crystallize during the sintering process, forming CdSe nanoparticles. The
    presence of CdSe nanoparticles inhibits SnSe grain growth during the consolidation
    step due to Zener pinning, yielding a material with a high density of grain boundaries.
    Moreover, the resulting SnSe–CdSe nanocomposites present a large number of defects
    at different length scales, which significantly reduce the thermal conductivity.
    The produced SnSe–CdSe nanocomposites exhibit thermoelectric figures of merit
    up to 2.2 at 786 K, which is among the highest reported for solution-processed
    SnSe.
acknowledgement: 'This work was financially supported by IST Austria and the Werner
  Siemens Foundation. Y.L. acknowledges funding from the European Union’s Horizon
  2020 research and innovation program under the Marie Sklodowska-Curie grant agreement
  No. 754411. S.L. and M.C. received funding from the European Union’s Horizon 2020
  research and innovation program under the Marie Skłodowska-Curie Grant Agreement
  No. 665385. J.D. acknowledges funding from the European Union’s Horizon 2020 research
  and innovation program under the Marie Sklodowska-Curie grant agreement no. 665919
  (P-SPHERE) cofunded by Severo Ochoa Programme. C.C. acknowledges funding from the
  FWF “Lise Meitner Fellowship” grant agreement M 2889-N. Y.Y. and O.C.-M. acknowledge
  the financial support from DFG within the project SFB 917: Nanoswitches. M.C.S.
  received funding from the European Union’s Horizon 2020 research and innovation
  programme under the Marie Skłodowska-Curie grant agreement No. 754510 (PROBIST)
  and the Severo Ochoa programme. J.D. received funding from the European Union’s
  Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie
  grant agreement No. 665919 (P-SPHERE) cofunded by Severo Ochoa Programme. The ICN2
  is funded by the CERCA Program/Generalitat de Catalunya and by the Severo Ochoa
  program of the Spanish Ministry of Economy, Industry, and Competitiveness (MINECO,
  grant no. SEV-2017-0706). ICN2 acknowledges funding from Generalitat de Catalunya
  2017 SGR 327 and the Spanish MINECO project NANOGEN (PID2020-116093RB-C43). This
  project received funding from the European Union’s Horizon 2020 research and innovation
  program under grant agreement No. 823717-ESTEEM3. The FIB sample preparation was
  conducted in the LMA-INA-Universidad de Zaragoza.'
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Yu
  full_name: Liu, Yu
  id: 2A70014E-F248-11E8-B48F-1D18A9856A87
  last_name: Liu
  orcid: 0000-0001-7313-6740
- first_name: Mariano
  full_name: Calcabrini, Mariano
  id: 45D7531A-F248-11E8-B48F-1D18A9856A87
  last_name: Calcabrini
- first_name: Yuan
  full_name: Yu, Yuan
  last_name: Yu
- first_name: Seungho
  full_name: Lee, Seungho
  id: BB243B88-D767-11E9-B658-BC13E6697425
  last_name: Lee
  orcid: 0000-0002-6962-8598
- first_name: Cheng
  full_name: Chang, Cheng
  id: 9E331C2E-9F27-11E9-AE48-5033E6697425
  last_name: Chang
  orcid: 0000-0002-9515-4277
- first_name: Jérémy
  full_name: David, Jérémy
  last_name: David
- first_name: Tanmoy
  full_name: Ghosh, Tanmoy
  id: a5fc9bc3-feff-11ea-93fe-e8015a3c7e9d
  last_name: Ghosh
- first_name: Maria Chiara
  full_name: Spadaro, Maria Chiara
  last_name: Spadaro
- first_name: Chenyang
  full_name: Xie, Chenyang
  last_name: Xie
- first_name: Oana
  full_name: Cojocaru-Mirédin, Oana
  last_name: Cojocaru-Mirédin
- first_name: Jordi
  full_name: Arbiol, Jordi
  last_name: Arbiol
- first_name: Maria
  full_name: Ibáñez, Maria
  id: 43C61214-F248-11E8-B48F-1D18A9856A87
  last_name: Ibáñez
  orcid: 0000-0001-5013-2843
citation:
  ama: Liu Y, Calcabrini M, Yu Y, et al. Defect engineering in solution-processed
    polycrystalline SnSe leads to high thermoelectric performance. <i>ACS Nano</i>.
    2022;16(1):78-88. doi:<a href="https://doi.org/10.1021/acsnano.1c06720">10.1021/acsnano.1c06720</a>
  apa: Liu, Y., Calcabrini, M., Yu, Y., Lee, S., Chang, C., David, J., … Ibáñez, M.
    (2022). Defect engineering in solution-processed polycrystalline SnSe leads to
    high thermoelectric performance. <i>ACS Nano</i>. American Chemical Society .
    <a href="https://doi.org/10.1021/acsnano.1c06720">https://doi.org/10.1021/acsnano.1c06720</a>
  chicago: Liu, Yu, Mariano Calcabrini, Yuan Yu, Seungho Lee, Cheng Chang, Jérémy
    David, Tanmoy Ghosh, et al. “Defect Engineering in Solution-Processed Polycrystalline
    SnSe Leads to High Thermoelectric Performance.” <i>ACS Nano</i>. American Chemical
    Society , 2022. <a href="https://doi.org/10.1021/acsnano.1c06720">https://doi.org/10.1021/acsnano.1c06720</a>.
  ieee: Y. Liu <i>et al.</i>, “Defect engineering in solution-processed polycrystalline
    SnSe leads to high thermoelectric performance,” <i>ACS Nano</i>, vol. 16, no.
    1. American Chemical Society , pp. 78–88, 2022.
  ista: Liu Y, Calcabrini M, Yu Y, Lee S, Chang C, David J, Ghosh T, Spadaro MC, Xie
    C, Cojocaru-Mirédin O, Arbiol J, Ibáñez M. 2022. Defect engineering in solution-processed
    polycrystalline SnSe leads to high thermoelectric performance. ACS Nano. 16(1),
    78–88.
  mla: Liu, Yu, et al. “Defect Engineering in Solution-Processed Polycrystalline SnSe
    Leads to High Thermoelectric Performance.” <i>ACS Nano</i>, vol. 16, no. 1, American
    Chemical Society , 2022, pp. 78–88, doi:<a href="https://doi.org/10.1021/acsnano.1c06720">10.1021/acsnano.1c06720</a>.
  short: Y. Liu, M. Calcabrini, Y. Yu, S. Lee, C. Chang, J. David, T. Ghosh, M.C.
    Spadaro, C. Xie, O. Cojocaru-Mirédin, J. Arbiol, M. Ibáñez, ACS Nano 16 (2022)
    78–88.
date_created: 2021-09-24T07:55:12Z
date_published: 2022-01-25T00:00:00Z
date_updated: 2023-08-02T14:41:05Z
day: '25'
ddc:
- '540'
department:
- _id: MaIb
doi: 10.1021/acsnano.1c06720
ec_funded: 1
external_id:
  isi:
  - '000767223400008'
  pmid:
  - '34549956'
file:
- access_level: open_access
  checksum: 74f9c1aa5f95c0b992a4328e8e0247b4
  content_type: application/pdf
  creator: cchlebak
  date_created: 2022-03-02T16:17:29Z
  date_updated: 2022-03-02T16:17:29Z
  file_id: '10808'
  file_name: 2022_ACSNano_Liu.pdf
  file_size: 9050764
  relation: main_file
  success: 1
file_date_updated: 2022-03-02T16:17:29Z
has_accepted_license: '1'
intvolume: '        16'
isi: 1
issue: '1'
keyword:
- tin selenide
- nanocomposite
- grain growth
- Zener pinning
- thermoelectricity
- annealing
- solution processing
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: 78-88
pmid: 1
project:
- _id: 260C2330-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '754411'
  name: ISTplus - Postdoctoral Fellowships
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '665385'
  name: International IST Doctoral Program
- _id: 9B8F7476-BA93-11EA-9121-9846C619BF3A
  name: 'HighTE: The Werner Siemens Laboratory for the High Throughput Discovery of
    Semiconductors for Waste Heat Recovery'
- _id: 9B8804FC-BA93-11EA-9121-9846C619BF3A
  grant_number: M02889
  name: Bottom-up Engineering for Thermoelectric Applications
publication: ACS Nano
publication_identifier:
  eissn:
  - 1936-086X
  issn:
  - 1936-0851
publication_status: published
publisher: 'American Chemical Society '
quality_controlled: '1'
related_material:
  record:
  - id: '12885'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: Defect engineering in solution-processed polycrystalline SnSe leads to high
  thermoelectric performance
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 16
year: '2022'
...
---
_id: '10182'
abstract:
- lang: eng
  text: The mitochondrial oxidative phosphorylation system is central to cellular
    metabolism. It comprises five enzymatic complexes and two mobile electron carriers
    that work in a mitochondrial respiratory chain. By coupling the oxidation of reducing
    equivalents coming into mitochondria to the generation and subsequent dissipation
    of a proton gradient across the inner mitochondrial membrane, this electron transport
    chain drives the production of ATP, which is then used as a primary energy carrier
    in virtually all cellular processes. Minimal perturbations of the respiratory
    chain activity are linked to diseases; therefore, it is necessary to understand
    how these complexes are assembled and regulated and how they function. In this
    Review, we outline the latest assembly models for each individual complex, and
    we also highlight the recent discoveries indicating that the formation of larger
    assemblies, known as respiratory supercomplexes, originates from the association
    of the intermediates of individual complexes. We then discuss how recent cryo-electron
    microscopy structures have been key to answering open questions on the function
    of the electron transport chain in mitochondrial respiration and how supercomplexes
    and other factors, including metabolites, can regulate the activity of the single
    complexes. When relevant, we discuss how these mechanisms contribute to physiology
    and outline their deregulation in human diseases.
article_processing_charge: No
article_type: original
author:
- first_name: Irene
  full_name: Vercellino, Irene
  id: 3ED6AF16-F248-11E8-B48F-1D18A9856A87
  last_name: Vercellino
  orcid: ' 0000-0001-5618-3449'
- first_name: Leonid A
  full_name: Sazanov, Leonid A
  id: 338D39FE-F248-11E8-B48F-1D18A9856A87
  last_name: Sazanov
  orcid: 0000-0002-0977-7989
citation:
  ama: Vercellino I, Sazanov LA. The assembly, regulation and function of the mitochondrial
    respiratory chain. <i>Nature Reviews Molecular Cell Biology</i>. 2022;23:141–161.
    doi:<a href="https://doi.org/10.1038/s41580-021-00415-0">10.1038/s41580-021-00415-0</a>
  apa: Vercellino, I., &#38; Sazanov, L. A. (2022). The assembly, regulation and function
    of the mitochondrial respiratory chain. <i>Nature Reviews Molecular Cell Biology</i>.
    Springer Nature. <a href="https://doi.org/10.1038/s41580-021-00415-0">https://doi.org/10.1038/s41580-021-00415-0</a>
  chicago: Vercellino, Irene, and Leonid A Sazanov. “The Assembly, Regulation and
    Function of the Mitochondrial Respiratory Chain.” <i>Nature Reviews Molecular
    Cell Biology</i>. Springer Nature, 2022. <a href="https://doi.org/10.1038/s41580-021-00415-0">https://doi.org/10.1038/s41580-021-00415-0</a>.
  ieee: I. Vercellino and L. A. Sazanov, “The assembly, regulation and function of
    the mitochondrial respiratory chain,” <i>Nature Reviews Molecular Cell Biology</i>,
    vol. 23. Springer Nature, pp. 141–161, 2022.
  ista: Vercellino I, Sazanov LA. 2022. The assembly, regulation and function of the
    mitochondrial respiratory chain. Nature Reviews Molecular Cell Biology. 23, 141–161.
  mla: Vercellino, Irene, and Leonid A. Sazanov. “The Assembly, Regulation and Function
    of the Mitochondrial Respiratory Chain.” <i>Nature Reviews Molecular Cell Biology</i>,
    vol. 23, Springer Nature, 2022, pp. 141–161, doi:<a href="https://doi.org/10.1038/s41580-021-00415-0">10.1038/s41580-021-00415-0</a>.
  short: I. Vercellino, L.A. Sazanov, Nature Reviews Molecular Cell Biology 23 (2022)
    141–161.
date_created: 2021-10-24T22:01:35Z
date_published: 2022-02-01T00:00:00Z
date_updated: 2023-08-02T06:55:42Z
day: '01'
department:
- _id: LeSa
doi: 10.1038/s41580-021-00415-0
external_id:
  isi:
  - '000705697100001'
  pmid:
  - '34621061'
intvolume: '        23'
isi: 1
language:
- iso: eng
month: '02'
oa_version: None
page: 141–161
pmid: 1
publication: Nature Reviews Molecular Cell Biology
publication_identifier:
  eissn:
  - 1471-0080
  issn:
  - 1471-0072
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: The assembly, regulation and function of the mitochondrial respiratory chain
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 23
year: '2022'
...
---
_id: '10208'
abstract:
- lang: eng
  text: It is practical to collect a huge amount of movement data and environmental
    context information along with the health signals of individuals because there
    is the emergence of new generations of positioning and tracking technologies and
    rapid advancements of health sensors. The study of the relations between these
    datasets and their sequence similarity analysis is of interest to many applications
    such as health monitoring and recommender systems. However, entering all movement
    parameters and health signals can lead to the complexity of the problem and an
    increase in its computational load. In this situation, dimension reduction techniques
    can be used to avoid consideration of simultaneous dependent parameters in the
    process of similarity measurement of the trajectories. The present study provides
    a framework, named CaDRAW, to use spatial–temporal data and movement parameters
    along with independent context information in the process of measuring the similarity
    of trajectories. In this regard, the omission of dependent movement characteristic
    signals is conducted by using an unsupervised feature selection dimension reduction
    technique. To evaluate the effectiveness of the proposed framework, it was applied
    to a real contextualized movement and related health signal datasets of individuals.
    The results indicated the capability of the proposed framework in measuring the
    similarity and in decreasing the characteristic signals in such a way that the
    similarity results -before and after reduction of dependent characteristic signals-
    have small differences. The mean differences between the obtained results before
    and after reducing the dimension were 0.029 and 0.023 for the round path, respectively.
acknowledgement: The third author acknowledges the funding received from the Wittgenstein
  Prize, Austrian Science Fund (FWF), grant no. Z 342-N31.
article_processing_charge: No
article_type: original
author:
- first_name: Samira
  full_name: Goudarzi, Samira
  last_name: Goudarzi
- first_name: Mohammad
  full_name: Sharif, Mohammad
  last_name: Sharif
- first_name: Farid
  full_name: Karimipour, Farid
  id: 2A2BCDC4-CF62-11E9-BE5E-3B1EE6697425
  last_name: Karimipour
  orcid: 0000-0001-6746-4174
citation:
  ama: Goudarzi S, Sharif M, Karimipour F. A context-aware dimension reduction framework
    for trajectory and health signal analyses. <i>Journal of Ambient Intelligence
    and Humanized Computing</i>. 2022;13:2621–2635. doi:<a href="https://doi.org/10.1007/s12652-021-03569-z">10.1007/s12652-021-03569-z</a>
  apa: Goudarzi, S., Sharif, M., &#38; Karimipour, F. (2022). A context-aware dimension
    reduction framework for trajectory and health signal analyses. <i>Journal of Ambient
    Intelligence and Humanized Computing</i>. Springer Nature. <a href="https://doi.org/10.1007/s12652-021-03569-z">https://doi.org/10.1007/s12652-021-03569-z</a>
  chicago: Goudarzi, Samira, Mohammad Sharif, and Farid Karimipour. “A Context-Aware
    Dimension Reduction Framework for Trajectory and Health Signal Analyses.” <i>Journal
    of Ambient Intelligence and Humanized Computing</i>. Springer Nature, 2022. <a
    href="https://doi.org/10.1007/s12652-021-03569-z">https://doi.org/10.1007/s12652-021-03569-z</a>.
  ieee: S. Goudarzi, M. Sharif, and F. Karimipour, “A context-aware dimension reduction
    framework for trajectory and health signal analyses,” <i>Journal of Ambient Intelligence
    and Humanized Computing</i>, vol. 13. Springer Nature, pp. 2621–2635, 2022.
  ista: Goudarzi S, Sharif M, Karimipour F. 2022. A context-aware dimension reduction
    framework for trajectory and health signal analyses. Journal of Ambient Intelligence
    and Humanized Computing. 13, 2621–2635.
  mla: Goudarzi, Samira, et al. “A Context-Aware Dimension Reduction Framework for
    Trajectory and Health Signal Analyses.” <i>Journal of Ambient Intelligence and
    Humanized Computing</i>, vol. 13, Springer Nature, 2022, pp. 2621–2635, doi:<a
    href="https://doi.org/10.1007/s12652-021-03569-z">10.1007/s12652-021-03569-z</a>.
  short: S. Goudarzi, M. Sharif, F. Karimipour, Journal of Ambient Intelligence and
    Humanized Computing 13 (2022) 2621–2635.
date_created: 2021-11-02T09:28:55Z
date_published: 2022-05-01T00:00:00Z
date_updated: 2023-08-02T13:31:48Z
day: '01'
ddc:
- '000'
department:
- _id: HeEd
doi: 10.1007/s12652-021-03569-z
external_id:
  isi:
  - '000712198000001'
file:
- access_level: open_access
  checksum: 0a8961416a9bb2be5a1cebda65468bcf
  content_type: application/pdf
  creator: fkarimip
  date_created: 2021-11-12T19:38:05Z
  date_updated: 2022-12-20T23:30:08Z
  embargo: 2022-11-12
  file_id: '10279'
  file_name: A Context‑aware Dimension Reduction Framework - Journal of Ambient Intelligence
    2021 (Preprint version).pdf
  file_size: 1634958
  relation: main_file
file_date_updated: 2022-12-20T23:30:08Z
has_accepted_license: '1'
intvolume: '        13'
isi: 1
keyword:
- general computer science
language:
- iso: eng
month: '05'
oa: 1
oa_version: Submitted Version
page: 2621–2635
project:
- _id: 268116B8-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: Z00342
  name: The Wittgenstein Prize
publication: Journal of Ambient Intelligence and Humanized Computing
publication_identifier:
  eissn:
  - 1868-5145
  issn:
  - 1868-5137
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: A context-aware dimension reduction framework for trajectory and health signal
  analyses
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 13
year: '2022'
...
---
_id: '10284'
abstract:
- lang: eng
  text: Infections early in life can have enduring effects on an organism's development
    and immunity. In this study, we show that this equally applies to developing ‘superorganisms’––incipient
    social insect colonies. When we exposed newly mated Lasius niger ant queens to
    a low pathogen dose, their colonies grew more slowly than controls before winter,
    but reached similar sizes afterwards. Independent of exposure, queen hibernation
    survival improved when the ratio of pupae to workers was small. Queens that reared
    fewer pupae before worker emergence exhibited lower pathogen levels, indicating
    that high brood rearing efforts interfere with the ability of the queen's immune
    system to suppress pathogen proliferation. Early-life queen pathogen exposure
    also improved the immunocompetence of her worker offspring, as demonstrated by
    challenging the workers to the same pathogen a year later. Transgenerational transfer
    of the queen's pathogen experience to her workforce can hence durably reduce the
    disease susceptibility of the whole superorganism.
acknowledged_ssus:
- _id: ScienComp
acknowledgement: The authors are grateful to G. Tkačik and V. Mireles for advice on
  data analyses and to A. Schloegl for help using the IST Austria HPC cluster for
  data processing. The authors thank J. Eilenberg for providing the fungal strain
  and A.V. Grasse for support with the molecular analysis. The authors also thank
  the Social Immunity group at IST Austria, in particular B. Milutinović, for discussions
  throughout and comments on the manuscript.
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Barbara E
  full_name: Casillas Perez, Barbara E
  id: 351ED2AA-F248-11E8-B48F-1D18A9856A87
  last_name: Casillas Perez
- first_name: Christopher
  full_name: Pull, Christopher
  id: 3C7F4840-F248-11E8-B48F-1D18A9856A87
  last_name: Pull
  orcid: 0000-0003-1122-3982
- first_name: Filip
  full_name: Naiser, Filip
  last_name: Naiser
- first_name: Elisabeth
  full_name: Naderlinger, Elisabeth
  id: 31757262-F248-11E8-B48F-1D18A9856A87
  last_name: Naderlinger
- first_name: Jiri
  full_name: Matas, Jiri
  last_name: Matas
- first_name: Sylvia
  full_name: Cremer, Sylvia
  id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
  last_name: Cremer
  orcid: 0000-0002-2193-3868
citation:
  ama: Casillas Perez BE, Pull C, Naiser F, Naderlinger E, Matas J, Cremer S. Early
    queen infection shapes developmental dynamics and induces long-term disease protection
    in incipient ant colonies. <i>Ecology Letters</i>. 2022;25(1):89-100. doi:<a href="https://doi.org/10.1111/ele.13907">10.1111/ele.13907</a>
  apa: Casillas Perez, B. E., Pull, C., Naiser, F., Naderlinger, E., Matas, J., &#38;
    Cremer, S. (2022). Early queen infection shapes developmental dynamics and induces
    long-term disease protection in incipient ant colonies. <i>Ecology Letters</i>.
    Wiley. <a href="https://doi.org/10.1111/ele.13907">https://doi.org/10.1111/ele.13907</a>
  chicago: Casillas Perez, Barbara E, Christopher Pull, Filip Naiser, Elisabeth Naderlinger,
    Jiri Matas, and Sylvia Cremer. “Early Queen Infection Shapes Developmental Dynamics
    and Induces Long-Term Disease Protection in Incipient Ant Colonies.” <i>Ecology
    Letters</i>. Wiley, 2022. <a href="https://doi.org/10.1111/ele.13907">https://doi.org/10.1111/ele.13907</a>.
  ieee: B. E. Casillas Perez, C. Pull, F. Naiser, E. Naderlinger, J. Matas, and S.
    Cremer, “Early queen infection shapes developmental dynamics and induces long-term
    disease protection in incipient ant colonies,” <i>Ecology Letters</i>, vol. 25,
    no. 1. Wiley, pp. 89–100, 2022.
  ista: Casillas Perez BE, Pull C, Naiser F, Naderlinger E, Matas J, Cremer S. 2022.
    Early queen infection shapes developmental dynamics and induces long-term disease
    protection in incipient ant colonies. Ecology Letters. 25(1), 89–100.
  mla: Casillas Perez, Barbara E., et al. “Early Queen Infection Shapes Developmental
    Dynamics and Induces Long-Term Disease Protection in Incipient Ant Colonies.”
    <i>Ecology Letters</i>, vol. 25, no. 1, Wiley, 2022, pp. 89–100, doi:<a href="https://doi.org/10.1111/ele.13907">10.1111/ele.13907</a>.
  short: B.E. Casillas Perez, C. Pull, F. Naiser, E. Naderlinger, J. Matas, S. Cremer,
    Ecology Letters 25 (2022) 89–100.
date_created: 2021-11-14T23:01:25Z
date_published: 2022-01-01T00:00:00Z
date_updated: 2023-08-14T11:45:29Z
day: '01'
ddc:
- '573'
department:
- _id: SyCr
doi: 10.1111/ele.13907
ec_funded: 1
external_id:
  isi:
  - '000713396100001'
  pmid:
  - '34725912'
file:
- access_level: open_access
  checksum: 0bd4210400e9876609b7c538ab4f9a3c
  content_type: application/pdf
  creator: cchlebak
  date_created: 2022-02-03T13:37:11Z
  date_updated: 2022-02-03T13:37:11Z
  file_id: '10721'
  file_name: 2021_EcologyLetters_CasillasPerez.pdf
  file_size: 700087
  relation: main_file
  success: 1
file_date_updated: 2022-02-03T13:37:11Z
has_accepted_license: '1'
intvolume: '        25'
isi: 1
issue: '1'
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: 89-100
pmid: 1
project:
- _id: 2649B4DE-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '771402'
  name: Epidemics in ant societies on a chip
publication: Ecology Letters
publication_identifier:
  eissn:
  - 1461-0248
  issn:
  - 1461-023X
publication_status: published
publisher: Wiley
quality_controlled: '1'
related_material:
  record:
  - id: '13061'
    relation: research_data
    status: public
scopus_import: '1'
status: public
title: Early queen infection shapes developmental dynamics and induces long-term disease
  protection in incipient ant colonies
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 25
year: '2022'
...
---
_id: '10335'
abstract:
- lang: eng
  text: "Van der Holst and Pendavingh introduced a graph parameter σ, which coincides
    with the more famous Colin de Verdière graph parameter μ for small values. However,
    the definition of a is much more geometric/topological directly reflecting embeddability
    properties of the graph. They proved μ(G) ≤ σ(G) + 2 and conjectured σ(G) ≤ σ(G)
    for any graph G. We confirm this conjecture. As far as we know, this is the first
    topological upper bound on σ(G) which is, in general, tight.\r\nEquality between
    μ and σ does not hold in general as van der Holst and Pendavingh showed that there
    is a graph G with μ(G) ≤ 18 and σ(G) ≥ 20. We show that the gap appears at much
    smaller values, namely, we exhibit a graph H for which μ(H) ≥ 7 and σ(H) ≥ 8.
    We also prove that, in general, the gap can be large: The incidence graphs Hq
    of finite projective planes of order q satisfy μ(Hq) ∈ O(q3/2) and σ(Hq) ≥ q2."
acknowledgement: 'V. K. gratefully acknowledges the support of Austrian Science Fund
  (FWF): P 30902-N35. This work was done mostly while he was employed at the University
  of Innsbruck. During the early stage of this research, V. K. was partially supported
  by Charles University project GAUK 926416. M. T. is supported by the grant no. 19-04113Y
  of the Czech Science Foundation(GA ˇCR) and partially supported by Charles University
  project UNCE/SCI/004.'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Vojtech
  full_name: Kaluza, Vojtech
  id: 21AE5134-9EAC-11EA-BEA2-D7BD3DDC885E
  last_name: Kaluza
  orcid: 0000-0002-2512-8698
- first_name: Martin
  full_name: Tancer, Martin
  id: 38AC689C-F248-11E8-B48F-1D18A9856A87
  last_name: Tancer
  orcid: 0000-0002-1191-6714
citation:
  ama: Kaluza V, Tancer M. Even maps, the Colin de Verdière number and representations
    of graphs. <i>Combinatorica</i>. 2022;42:1317-1345. doi:<a href="https://doi.org/10.1007/s00493-021-4443-7">10.1007/s00493-021-4443-7</a>
  apa: Kaluza, V., &#38; Tancer, M. (2022). Even maps, the Colin de Verdière number
    and representations of graphs. <i>Combinatorica</i>. Springer Nature. <a href="https://doi.org/10.1007/s00493-021-4443-7">https://doi.org/10.1007/s00493-021-4443-7</a>
  chicago: Kaluza, Vojtech, and Martin Tancer. “Even Maps, the Colin de Verdière Number
    and Representations of Graphs.” <i>Combinatorica</i>. Springer Nature, 2022. <a
    href="https://doi.org/10.1007/s00493-021-4443-7">https://doi.org/10.1007/s00493-021-4443-7</a>.
  ieee: V. Kaluza and M. Tancer, “Even maps, the Colin de Verdière number and representations
    of graphs,” <i>Combinatorica</i>, vol. 42. Springer Nature, pp. 1317–1345, 2022.
  ista: Kaluza V, Tancer M. 2022. Even maps, the Colin de Verdière number and representations
    of graphs. Combinatorica. 42, 1317–1345.
  mla: Kaluza, Vojtech, and Martin Tancer. “Even Maps, the Colin de Verdière Number
    and Representations of Graphs.” <i>Combinatorica</i>, vol. 42, Springer Nature,
    2022, pp. 1317–45, doi:<a href="https://doi.org/10.1007/s00493-021-4443-7">10.1007/s00493-021-4443-7</a>.
  short: V. Kaluza, M. Tancer, Combinatorica 42 (2022) 1317–1345.
date_created: 2021-11-25T13:49:16Z
date_published: 2022-12-01T00:00:00Z
date_updated: 2023-08-02T06:43:27Z
day: '01'
ddc:
- '514'
- '516'
department:
- _id: UlWa
doi: 10.1007/s00493-021-4443-7
external_id:
  arxiv:
  - '1907.05055'
  isi:
  - '000798210100003'
intvolume: '        42'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: ' https://doi.org/10.48550/arXiv.1907.05055'
month: '12'
oa: 1
oa_version: Preprint
page: 1317-1345
publication: Combinatorica
publication_identifier:
  issn:
  - 0209-9683
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Even maps, the Colin de Verdière number and representations of graphs
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 42
year: '2022'
...
---
_id: '10364'
abstract:
- lang: eng
  text: 'This paper characterizes the latency of the simplified successive-cancellation
    (SSC) decoding scheme for polar codes under hardware resource constraints. In
    particular, when the number of processing elements P that can perform SSC decoding
    operations in parallel is limited, as is the case in practice, the latency of
    SSC decoding is O(N1-1/μ + N/P log2 log2 N/P), where N is the block length of
    the code and μ is the scaling exponent of the channel. Three direct consequences
    of this bound are presented. First, in a fully-parallel implementation where P
    = N/2, the latency of SSC decoding is O(N1-1/μ), which is sublinear in the block
    length. This recovers a result from our earlier work. Second, in a fully-serial
    implementation where P = 1, the latency of SSC decoding scales as O(N log2 log2
    N). The multiplicative constant is also calculated: we show that the latency of
    SSC decoding when P = 1 is given by (2 + o(1))N log2 log2 N. Third, in a semi-parallel
    implementation, the smallest P that gives the same latency as that of the fully-parallel
    implementation is P = N1/μ. The tightness of our bound on SSC decoding latency
    and the applicability of the foregoing results is validated through extensive
    simulations.'
acknowledgement: "S. A. Hashemi is supported by a Postdoctoral Fellowship from the
  Natural Sciences and\r\nEngineering Research Council of Canada (NSERC) and by Huawei.
  M. Mondelli is partially\r\nsupported by the 2019 Lopez-Loreta Prize. A. Fazeli
  and A. Vardy were supported in part by\r\nthe National Science Foundation under
  Grant CCF-1764104."
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Seyyed Ali
  full_name: Hashemi, Seyyed Ali
  last_name: Hashemi
- first_name: Marco
  full_name: Mondelli, Marco
  id: 27EB676C-8706-11E9-9510-7717E6697425
  last_name: Mondelli
  orcid: 0000-0002-3242-7020
- first_name: Arman
  full_name: Fazeli, Arman
  last_name: Fazeli
- first_name: Alexander
  full_name: Vardy, Alexander
  last_name: Vardy
- first_name: John
  full_name: Cioffi, John
  last_name: Cioffi
- first_name: Andrea
  full_name: Goldsmith, Andrea
  last_name: Goldsmith
citation:
  ama: Hashemi SA, Mondelli M, Fazeli A, Vardy A, Cioffi J, Goldsmith A. Parallelism
    versus latency in simplified successive-cancellation decoding of polar codes.
    <i>IEEE Transactions on Wireless Communications</i>. 2022;21(6):3909-3920. doi:<a
    href="https://doi.org/10.1109/TWC.2021.3125626">10.1109/TWC.2021.3125626</a>
  apa: Hashemi, S. A., Mondelli, M., Fazeli, A., Vardy, A., Cioffi, J., &#38; Goldsmith,
    A. (2022). Parallelism versus latency in simplified successive-cancellation decoding
    of polar codes. <i>IEEE Transactions on Wireless Communications</i>. Institute
    of Electrical and Electronics Engineers. <a href="https://doi.org/10.1109/TWC.2021.3125626">https://doi.org/10.1109/TWC.2021.3125626</a>
  chicago: Hashemi, Seyyed Ali, Marco Mondelli, Arman Fazeli, Alexander Vardy, John
    Cioffi, and Andrea Goldsmith. “Parallelism versus Latency in Simplified Successive-Cancellation
    Decoding of Polar Codes.” <i>IEEE Transactions on Wireless Communications</i>.
    Institute of Electrical and Electronics Engineers, 2022. <a href="https://doi.org/10.1109/TWC.2021.3125626">https://doi.org/10.1109/TWC.2021.3125626</a>.
  ieee: S. A. Hashemi, M. Mondelli, A. Fazeli, A. Vardy, J. Cioffi, and A. Goldsmith,
    “Parallelism versus latency in simplified successive-cancellation decoding of
    polar codes,” <i>IEEE Transactions on Wireless Communications</i>, vol. 21, no.
    6. Institute of Electrical and Electronics Engineers, pp. 3909–3920, 2022.
  ista: Hashemi SA, Mondelli M, Fazeli A, Vardy A, Cioffi J, Goldsmith A. 2022. Parallelism
    versus latency in simplified successive-cancellation decoding of polar codes.
    IEEE Transactions on Wireless Communications. 21(6), 3909–3920.
  mla: Hashemi, Seyyed Ali, et al. “Parallelism versus Latency in Simplified Successive-Cancellation
    Decoding of Polar Codes.” <i>IEEE Transactions on Wireless Communications</i>,
    vol. 21, no. 6, Institute of Electrical and Electronics Engineers, 2022, pp. 3909–20,
    doi:<a href="https://doi.org/10.1109/TWC.2021.3125626">10.1109/TWC.2021.3125626</a>.
  short: S.A. Hashemi, M. Mondelli, A. Fazeli, A. Vardy, J. Cioffi, A. Goldsmith,
    IEEE Transactions on Wireless Communications 21 (2022) 3909–3920.
date_created: 2021-11-28T23:01:29Z
date_published: 2022-06-01T00:00:00Z
date_updated: 2024-09-10T13:03:18Z
day: '01'
department:
- _id: MaMo
doi: 10.1109/TWC.2021.3125626
external_id:
  arxiv:
  - '2012.13378'
  isi:
  - '000809406400028'
intvolume: '        21'
isi: 1
issue: '6'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/2012.13378
month: '06'
oa: 1
oa_version: Preprint
page: 3909-3920
project:
- _id: 059876FA-7A3F-11EA-A408-12923DDC885E
  name: Prix Lopez-Loretta 2019 - Marco Mondelli
publication: IEEE Transactions on Wireless Communications
publication_identifier:
  eissn:
  - 1558-2248
  issn:
  - 1536-1276
publication_status: published
publisher: Institute of Electrical and Electronics Engineers
quality_controlled: '1'
related_material:
  record:
  - id: '10053'
    relation: earlier_version
    status: public
scopus_import: '1'
status: public
title: Parallelism versus latency in simplified successive-cancellation decoding of
  polar codes
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 21
year: '2022'
...
---
_id: '10411'
abstract:
- lang: eng
  text: The phytohormone auxin is the major growth regulator governing tropic responses
    including gravitropism. Auxin build-up at the lower side of stimulated shoots
    promotes cell expansion, whereas in roots it inhibits growth, leading to upward
    shoot bending and downward root bending, respectively. Yet it remains an enigma
    how the same signal can trigger such opposite cellular responses. In this review,
    we discuss several recent unexpected insights into the mechanisms underlying auxin
    regulation of growth, challenging several existing models. We focus on the divergent
    mechanisms of apoplastic pH regulation in shoots and roots revisiting the classical
    Acid Growth Theory and discuss coordinated involvement of multiple auxin signaling
    pathways. From this emerges a more comprehensive, updated picture how auxin regulates
    growth.
acknowledgement: The authors thank Alexandra Mally for editing the text. This work
  was supported by the Austrian Science Fund (FWF) I 3630-B25 to Jiří Friml and the
  DOC Fellowship of the Austrian Academy of Sciences to Lanxin Li. All figures were
  created with BioRender.com.
article_processing_charge: No
article_type: original
author:
- first_name: Lanxin
  full_name: Li, Lanxin
  id: 367EF8FA-F248-11E8-B48F-1D18A9856A87
  last_name: Li
  orcid: 0000-0002-5607-272X
- first_name: Michelle C
  full_name: Gallei, Michelle C
  id: 35A03822-F248-11E8-B48F-1D18A9856A87
  last_name: Gallei
  orcid: 0000-0003-1286-7368
- first_name: Jiří
  full_name: Friml, Jiří
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
citation:
  ama: 'Li L, Gallei MC, Friml J. Bending to auxin: Fast acid growth for tropisms.
    <i>Trends in Plant Science</i>. 2022;27(5):440-449. doi:<a href="https://doi.org/10.1016/j.tplants.2021.11.006">10.1016/j.tplants.2021.11.006</a>'
  apa: 'Li, L., Gallei, M. C., &#38; Friml, J. (2022). Bending to auxin: Fast acid
    growth for tropisms. <i>Trends in Plant Science</i>. Cell Press. <a href="https://doi.org/10.1016/j.tplants.2021.11.006">https://doi.org/10.1016/j.tplants.2021.11.006</a>'
  chicago: 'Li, Lanxin, Michelle C Gallei, and Jiří Friml. “Bending to Auxin: Fast
    Acid Growth for Tropisms.” <i>Trends in Plant Science</i>. Cell Press, 2022. <a
    href="https://doi.org/10.1016/j.tplants.2021.11.006">https://doi.org/10.1016/j.tplants.2021.11.006</a>.'
  ieee: 'L. Li, M. C. Gallei, and J. Friml, “Bending to auxin: Fast acid growth for
    tropisms,” <i>Trends in Plant Science</i>, vol. 27, no. 5. Cell Press, pp. 440–449,
    2022.'
  ista: 'Li L, Gallei MC, Friml J. 2022. Bending to auxin: Fast acid growth for tropisms.
    Trends in Plant Science. 27(5), 440–449.'
  mla: 'Li, Lanxin, et al. “Bending to Auxin: Fast Acid Growth for Tropisms.” <i>Trends
    in Plant Science</i>, vol. 27, no. 5, Cell Press, 2022, pp. 440–49, doi:<a href="https://doi.org/10.1016/j.tplants.2021.11.006">10.1016/j.tplants.2021.11.006</a>.'
  short: L. Li, M.C. Gallei, J. Friml, Trends in Plant Science 27 (2022) 440–449.
date_created: 2021-12-05T23:01:43Z
date_published: 2022-05-01T00:00:00Z
date_updated: 2024-10-29T10:12:33Z
day: '01'
ddc:
- '580'
department:
- _id: JiFr
doi: 10.1016/j.tplants.2021.11.006
external_id:
  isi:
  - '000793707900005'
  pmid:
  - '34848141'
file:
- access_level: open_access
  checksum: 3d94980ee1ff6bec100dd813f6a921a6
  content_type: application/pdf
  creator: amally
  date_created: 2023-11-02T17:00:03Z
  date_updated: 2023-11-02T17:00:03Z
  file_id: '14480'
  file_name: Li Plants 2021_accepted.pdf
  file_size: 805779
  relation: main_file
  success: 1
file_date_updated: 2023-11-02T17:00:03Z
has_accepted_license: '1'
intvolume: '        27'
isi: 1
issue: '5'
language:
- iso: eng
month: '05'
oa: 1
oa_version: Submitted Version
page: 440-449
pmid: 1
project:
- _id: 26538374-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: I03630
  name: Molecular mechanisms of endocytic cargo recognition in plants
- _id: 26B4D67E-B435-11E9-9278-68D0E5697425
  grant_number: '25351'
  name: 'A Case Study of Plant Growth Regulation: Molecular Mechanism of Auxin-mediated
    Rapid Growth Inhibition in Arabidopsis Root'
publication: Trends in Plant Science
publication_identifier:
  issn:
  - 1360-1385
publication_status: published
publisher: Cell Press
quality_controlled: '1'
related_material:
  record:
  - id: '11626'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: 'Bending to auxin: Fast acid growth for tropisms'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 27
year: '2022'
...
---
_id: '10413'
abstract:
- lang: eng
  text: Motivated by the recent introduction of the intrinsic semilattice entropy,
    we study generalized quasi-metric semilattices and their categories. We investigate
    the relationship between these objects and generalized semivaluations, extending
    Nakamura and Schellekens' approach. Finally, we use this correspondence to compare
    the intrinsic semilattice entropy and the semigroup entropy induced in particular
    situations, like sets, torsion abelian groups and vector spaces.
acknowledgement: Dedicated to the memory of Hans-Peter Künzi.
article_number: '107916'
article_processing_charge: No
article_type: original
author:
- first_name: Dikran
  full_name: Dikranjan, Dikran
  last_name: Dikranjan
- first_name: Anna
  full_name: Giordano Bruno, Anna
  last_name: Giordano Bruno
- first_name: Hans Peter
  full_name: Künzi, Hans Peter
  last_name: Künzi
- first_name: Nicolò
  full_name: Zava, Nicolò
  id: c8b3499c-7a77-11eb-b046-aa368cbbf2ad
  last_name: Zava
  orcid: 0000-0001-8686-1888
- first_name: Daniele
  full_name: Toller, Daniele
  last_name: Toller
citation:
  ama: Dikranjan D, Giordano Bruno A, Künzi HP, Zava N, Toller D. Generalized quasi-metric
    semilattices. <i>Topology and its Applications</i>. 2022;309. doi:<a href="https://doi.org/10.1016/j.topol.2021.107916">10.1016/j.topol.2021.107916</a>
  apa: Dikranjan, D., Giordano Bruno, A., Künzi, H. P., Zava, N., &#38; Toller, D.
    (2022). Generalized quasi-metric semilattices. <i>Topology and Its Applications</i>.
    Elsevier. <a href="https://doi.org/10.1016/j.topol.2021.107916">https://doi.org/10.1016/j.topol.2021.107916</a>
  chicago: Dikranjan, Dikran, Anna Giordano Bruno, Hans Peter Künzi, Nicolò Zava,
    and Daniele Toller. “Generalized Quasi-Metric Semilattices.” <i>Topology and Its
    Applications</i>. Elsevier, 2022. <a href="https://doi.org/10.1016/j.topol.2021.107916">https://doi.org/10.1016/j.topol.2021.107916</a>.
  ieee: D. Dikranjan, A. Giordano Bruno, H. P. Künzi, N. Zava, and D. Toller, “Generalized
    quasi-metric semilattices,” <i>Topology and its Applications</i>, vol. 309. Elsevier,
    2022.
  ista: Dikranjan D, Giordano Bruno A, Künzi HP, Zava N, Toller D. 2022. Generalized
    quasi-metric semilattices. Topology and its Applications. 309, 107916.
  mla: Dikranjan, Dikran, et al. “Generalized Quasi-Metric Semilattices.” <i>Topology
    and Its Applications</i>, vol. 309, 107916, Elsevier, 2022, doi:<a href="https://doi.org/10.1016/j.topol.2021.107916">10.1016/j.topol.2021.107916</a>.
  short: D. Dikranjan, A. Giordano Bruno, H.P. Künzi, N. Zava, D. Toller, Topology
    and Its Applications 309 (2022).
date_created: 2021-12-05T23:01:44Z
date_published: 2022-03-15T00:00:00Z
date_updated: 2023-08-02T13:33:24Z
day: '15'
department:
- _id: HeEd
doi: 10.1016/j.topol.2021.107916
external_id:
  isi:
  - '000791838800012'
intvolume: '       309'
isi: 1
language:
- iso: eng
month: '03'
oa_version: None
publication: Topology and its Applications
publication_identifier:
  issn:
  - 0166-8641
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Generalized quasi-metric semilattices
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 309
year: '2022'
...
---
_id: '10530'
abstract:
- lang: eng
  text: "Cell dispersion from a confined area is fundamental in a number of biological
    processes,\r\nincluding cancer metastasis. To date, a quantitative understanding
    of the interplay of single\r\ncell motility, cell proliferation, and intercellular
    contacts remains elusive. In particular, the role\r\nof E- and N-Cadherin junctions,
    central components of intercellular contacts, is still\r\ncontroversial. Combining
    theoretical modeling with in vitro observations, we investigate the\r\ncollective
    spreading behavior of colonies of human cancer cells (T24). The spreading of these\r\ncolonies
    is driven by stochastic single-cell migration with frequent transient cell-cell
    contacts.\r\nWe find that inhibition of E- and N-Cadherin junctions decreases
    colony spreading and average\r\nspreading velocities, without affecting the strength
    of correlations in spreading velocities of\r\nneighboring cells. Based on a biophysical
    simulation model for cell migration, we show that the\r\nbehavioral changes upon
    disruption of these junctions can be explained by reduced repulsive\r\nexcluded
    volume interactions between cells. This suggests that in cancer cell migration,\r\ncadherin-based
    intercellular contacts sharpen cell boundaries leading to repulsive rather than\r\ncohesive
    interactions between cells, thereby promoting efficient cell spreading during
    collective\r\nmigration.\r\n"
acknowledgement: Funded by the Deutsche Forschungsgemeinschaft (DFG, German Research
  Foundation) - Project-ID 201269156 - SFB 1032 (Projects B8 and B12). D.B.B. is supported
  in part by a DFG fellowship within the Graduate School of Quantitative Biosciences
  Munich (QBM) and by the Joachim Herz Stiftung.
article_processing_charge: No
article_type: original
author:
- first_name: Themistoklis
  full_name: Zisis, Themistoklis
  last_name: Zisis
- first_name: David
  full_name: Brückner, David
  id: e1e86031-6537-11eb-953a-f7ab92be508d
  last_name: Brückner
  orcid: 0000-0001-7205-2975
- first_name: Tom
  full_name: Brandstätter, Tom
  last_name: Brandstätter
- first_name: Wei Xiong
  full_name: Siow, Wei Xiong
  last_name: Siow
- first_name: Joseph
  full_name: d’Alessandro, Joseph
  last_name: d’Alessandro
- first_name: Angelika M.
  full_name: Vollmar, Angelika M.
  last_name: Vollmar
- first_name: Chase P.
  full_name: Broedersz, Chase P.
  last_name: Broedersz
- first_name: Stefan
  full_name: Zahler, Stefan
  last_name: Zahler
citation:
  ama: Zisis T, Brückner D, Brandstätter T, et al. Disentangling cadherin-mediated
    cell-cell interactions in collective cancer cell migration. <i>Biophysical Journal</i>.
    2022;121(1):P44-60. doi:<a href="https://doi.org/10.1016/j.bpj.2021.12.006">10.1016/j.bpj.2021.12.006</a>
  apa: Zisis, T., Brückner, D., Brandstätter, T., Siow, W. X., d’Alessandro, J., Vollmar,
    A. M., … Zahler, S. (2022). Disentangling cadherin-mediated cell-cell interactions
    in collective cancer cell migration. <i>Biophysical Journal</i>. Elsevier. <a
    href="https://doi.org/10.1016/j.bpj.2021.12.006">https://doi.org/10.1016/j.bpj.2021.12.006</a>
  chicago: Zisis, Themistoklis, David Brückner, Tom Brandstätter, Wei Xiong Siow,
    Joseph d’Alessandro, Angelika M. Vollmar, Chase P. Broedersz, and Stefan Zahler.
    “Disentangling Cadherin-Mediated Cell-Cell Interactions in Collective Cancer Cell
    Migration.” <i>Biophysical Journal</i>. Elsevier, 2022. <a href="https://doi.org/10.1016/j.bpj.2021.12.006">https://doi.org/10.1016/j.bpj.2021.12.006</a>.
  ieee: T. Zisis <i>et al.</i>, “Disentangling cadherin-mediated cell-cell interactions
    in collective cancer cell migration,” <i>Biophysical Journal</i>, vol. 121, no.
    1. Elsevier, pp. P44-60, 2022.
  ista: Zisis T, Brückner D, Brandstätter T, Siow WX, d’Alessandro J, Vollmar AM,
    Broedersz CP, Zahler S. 2022. Disentangling cadherin-mediated cell-cell interactions
    in collective cancer cell migration. Biophysical Journal. 121(1), P44-60.
  mla: Zisis, Themistoklis, et al. “Disentangling Cadherin-Mediated Cell-Cell Interactions
    in Collective Cancer Cell Migration.” <i>Biophysical Journal</i>, vol. 121, no.
    1, Elsevier, 2022, pp. P44-60, doi:<a href="https://doi.org/10.1016/j.bpj.2021.12.006">10.1016/j.bpj.2021.12.006</a>.
  short: T. Zisis, D. Brückner, T. Brandstätter, W.X. Siow, J. d’Alessandro, A.M.
    Vollmar, C.P. Broedersz, S. Zahler, Biophysical Journal 121 (2022) P44-60.
date_created: 2021-12-10T09:48:19Z
date_published: 2022-01-04T00:00:00Z
date_updated: 2023-08-02T13:34:25Z
day: '04'
ddc:
- '570'
department:
- _id: EdHa
- _id: GaTk
doi: 10.1016/j.bpj.2021.12.006
external_id:
  isi:
  - '000740815400007'
file:
- access_level: open_access
  checksum: 1aa7c3478e0c8256b973b632efd1f6b4
  content_type: application/pdf
  creator: dernst
  date_created: 2022-07-29T10:17:10Z
  date_updated: 2022-07-29T10:17:10Z
  file_id: '11697'
  file_name: 2022_BiophysicalJour_Zisis.pdf
  file_size: 4475504
  relation: main_file
  success: 1
file_date_updated: 2022-07-29T10:17:10Z
has_accepted_license: '1'
intvolume: '       121'
isi: 1
issue: '1'
keyword:
- Biophysics
language:
- iso: eng
month: '01'
oa: 1
oa_version: Published Version
page: P44-60
project:
- _id: 9B861AAC-BA93-11EA-9121-9846C619BF3A
  name: NOMIS Fellowship Program
publication: Biophysical Journal
publication_identifier:
  issn:
  - 0006-3495
publication_status: published
publisher: Elsevier
quality_controlled: '1'
status: public
title: Disentangling cadherin-mediated cell-cell interactions in collective cancer
  cell migration
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 121
year: '2022'
...
---
_id: '10547'
abstract:
- lang: eng
  text: "We establish global-in-time existence results for thermodynamically consistent
    reaction-(cross-)diffusion systems coupled to an equation describing heat transfer.
    Our main interest is to model species-dependent diffusivities,\r\nwhile at the
    same time ensuring thermodynamic consistency. A key difficulty of the non-isothermal
    case lies in the intrinsic presence of cross-diffusion type phenomena like the
    Soret and the Dufour effect: due to the temperature/energy dependence of the thermodynamic
    equilibria, a nonvanishing temperature gradient may drive a concentration flux
    even in a situation with constant concentrations; likewise, a nonvanishing concentration
    gradient may drive a heat flux even in a case of spatially constant temperature.
    We use time discretisation and regularisation techniques and derive a priori estimates
    based on a suitable entropy and the associated entropy production. Renormalised
    solutions are used in cases where non-integrable diffusion fluxes or reaction
    terms appear."
acknowledgement: M.K. gratefully acknowledges the hospitality of WIAS Berlin, where
  a major part of the project was carried out. The research stay of M.K. at WIAS Berlin
  was funded by the Austrian Federal Ministry of Education, Science and Research through
  a research fellowship for graduates of a promotio sub auspiciis. The research of
  A.M. has been partially supported by Deutsche Forschungsgemeinschaft (DFG) through
  the Collaborative Research Center SFB 1114 “Scaling Cascades in Complex Systems”
  (Project no. 235221301), Subproject C05 “Effective models for materials and interfaces
  with multiple scales”. J.F. and A.M. are grateful for the hospitality of the Erwin
  Schrödinger Institute in Vienna, where some ideas for this work have been developed.
  The authors are grateful to two anonymous referees for several helpful comments,
  in particular for the short proof of estimate (2.7).
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Julian L
  full_name: Fischer, Julian L
  id: 2C12A0B0-F248-11E8-B48F-1D18A9856A87
  last_name: Fischer
  orcid: 0000-0002-0479-558X
- first_name: Katharina
  full_name: Hopf, Katharina
  last_name: Hopf
- first_name: Michael
  full_name: Kniely, Michael
  id: 2CA2C08C-F248-11E8-B48F-1D18A9856A87
  last_name: Kniely
  orcid: 0000-0001-5645-4333
- first_name: Alexander
  full_name: Mielke, Alexander
  last_name: Mielke
citation:
  ama: Fischer JL, Hopf K, Kniely M, Mielke A. Global existence analysis of energy-reaction-diffusion
    systems. <i>SIAM Journal on Mathematical Analysis</i>. 2022;54(1):220-267. doi:<a
    href="https://doi.org/10.1137/20M1387237">10.1137/20M1387237</a>
  apa: Fischer, J. L., Hopf, K., Kniely, M., &#38; Mielke, A. (2022). Global existence
    analysis of energy-reaction-diffusion systems. <i>SIAM Journal on Mathematical
    Analysis</i>. Society for Industrial and Applied Mathematics. <a href="https://doi.org/10.1137/20M1387237">https://doi.org/10.1137/20M1387237</a>
  chicago: Fischer, Julian L, Katharina Hopf, Michael Kniely, and Alexander Mielke.
    “Global Existence Analysis of Energy-Reaction-Diffusion Systems.” <i>SIAM Journal
    on Mathematical Analysis</i>. Society for Industrial and Applied Mathematics,
    2022. <a href="https://doi.org/10.1137/20M1387237">https://doi.org/10.1137/20M1387237</a>.
  ieee: J. L. Fischer, K. Hopf, M. Kniely, and A. Mielke, “Global existence analysis
    of energy-reaction-diffusion systems,” <i>SIAM Journal on Mathematical Analysis</i>,
    vol. 54, no. 1. Society for Industrial and Applied Mathematics, pp. 220–267, 2022.
  ista: Fischer JL, Hopf K, Kniely M, Mielke A. 2022. Global existence analysis of
    energy-reaction-diffusion systems. SIAM Journal on Mathematical Analysis. 54(1),
    220–267.
  mla: Fischer, Julian L., et al. “Global Existence Analysis of Energy-Reaction-Diffusion
    Systems.” <i>SIAM Journal on Mathematical Analysis</i>, vol. 54, no. 1, Society
    for Industrial and Applied Mathematics, 2022, pp. 220–67, doi:<a href="https://doi.org/10.1137/20M1387237">10.1137/20M1387237</a>.
  short: J.L. Fischer, K. Hopf, M. Kniely, A. Mielke, SIAM Journal on Mathematical
    Analysis 54 (2022) 220–267.
date_created: 2021-12-16T12:08:56Z
date_published: 2022-01-04T00:00:00Z
date_updated: 2023-08-02T13:37:03Z
day: '04'
department:
- _id: JuFi
doi: 10.1137/20M1387237
external_id:
  arxiv:
  - '2012.03792 '
  isi:
  - '000762768000006'
intvolume: '        54'
isi: 1
issue: '1'
keyword:
- Energy-Reaction-Diffusion Systems
- Cross Diffusion
- Global-In-Time Existence of Weak/Renormalised Solutions
- Entropy Method
- Onsager System
- Soret/Dufour Effect
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/2012.03792
month: '01'
oa: 1
oa_version: Preprint
page: 220-267
publication: SIAM Journal on Mathematical Analysis
publication_identifier:
  issn:
  - 0036-1410
publication_status: published
publisher: Society for Industrial and Applied Mathematics
quality_controlled: '1'
scopus_import: '1'
status: public
title: Global existence analysis of energy-reaction-diffusion systems
type: journal_article
user_id: 4359f0d1-fa6c-11eb-b949-802e58b17ae8
volume: 54
year: '2022'
...
