---
_id: '4195'
abstract:
- lang: eng
  text: The effects of tri-iodothyronine (T3), which are known to affect cerebellar
    development, were tested on neuronal survival and differentiation of cultured
    cerebellar granule neurons. T3 in physiological concentrations increased both
    granule neuron survival after three days in culture and synaptic vesicle protein
    formation, as shown by immunostaining with antibodies against synaptophysin. Likewise,
    T3 increased the mRNA level for synapsin(I), but not that for GAP43 in granule
    neurons. Antibodies against microtubule associated protein Tau, which is expressed
    in developing neurites, showed that T3 also enhanced neurite formation.
article_processing_charge: No
article_type: original
author:
- first_name: Carl-Philipp J
  full_name: Heisenberg, Carl-Philipp J
  id: 39427864-F248-11E8-B48F-1D18A9856A87
  last_name: Heisenberg
  orcid: 0000-0002-0912-4566
- first_name: Hans
  full_name: Thoenen, Hans
  last_name: Thoenen
- first_name: Dan
  full_name: Lindholm, Dan
  last_name: Lindholm
citation:
  ama: Heisenberg C-PJ, Thoenen H, Lindholm D. Triiodothyronine Regulates Survival
    and Differentiation of Rat Cerebellar Granule Neurons. <i>Neuroreport</i>. 1992;3(8):685-688.
    doi:<a href="https://doi.org/10.1097/00001756-199208000-00008 ">10.1097/00001756-199208000-00008
    </a>
  apa: Heisenberg, C.-P. J., Thoenen, H., &#38; Lindholm, D. (1992). Triiodothyronine
    Regulates Survival and Differentiation of Rat Cerebellar Granule Neurons. <i>Neuroreport</i>.
    Lippincott, Williams &#38; Wilkins. <a href="https://doi.org/10.1097/00001756-199208000-00008
    ">https://doi.org/10.1097/00001756-199208000-00008 </a>
  chicago: Heisenberg, Carl-Philipp J, Hans Thoenen, and Dan Lindholm. “Triiodothyronine
    Regulates Survival and Differentiation of Rat Cerebellar Granule Neurons.” <i>Neuroreport</i>.
    Lippincott, Williams &#38; Wilkins, 1992. <a href="https://doi.org/10.1097/00001756-199208000-00008
    ">https://doi.org/10.1097/00001756-199208000-00008 </a>.
  ieee: C.-P. J. Heisenberg, H. Thoenen, and D. Lindholm, “Triiodothyronine Regulates
    Survival and Differentiation of Rat Cerebellar Granule Neurons,” <i>Neuroreport</i>,
    vol. 3, no. 8. Lippincott, Williams &#38; Wilkins, pp. 685–688, 1992.
  ista: Heisenberg C-PJ, Thoenen H, Lindholm D. 1992. Triiodothyronine Regulates Survival
    and Differentiation of Rat Cerebellar Granule Neurons. Neuroreport. 3(8), 685–688.
  mla: Heisenberg, Carl-Philipp J., et al. “Triiodothyronine Regulates Survival and
    Differentiation of Rat Cerebellar Granule Neurons.” <i>Neuroreport</i>, vol. 3,
    no. 8, Lippincott, Williams &#38; Wilkins, 1992, pp. 685–88, doi:<a href="https://doi.org/10.1097/00001756-199208000-00008
    ">10.1097/00001756-199208000-00008 </a>.
  short: C.-P.J. Heisenberg, H. Thoenen, D. Lindholm, Neuroreport 3 (1992) 685–688.
date_created: 2018-12-11T12:07:31Z
date_published: 1992-01-01T00:00:00Z
date_updated: 2022-03-15T15:25:24Z
day: '01'
doi: '10.1097/00001756-199208000-00008 '
extern: '1'
external_id:
  pmid:
  - '1387811 '
intvolume: '         3'
issue: '8'
language:
- iso: eng
main_file_link:
- url: https://journals.lww.com/neuroreport/abstract/1992/08000/tri_iodothyronine_regulates_survival_and.8.aspx
month: '01'
oa_version: None
page: 685 - 688
pmid: 1
publication: Neuroreport
publication_identifier:
  eissn:
  - 1473-558X
  issn:
  - 0959-4965
publication_status: published
publisher: Lippincott, Williams & Wilkins
publist_id: '1922'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Triiodothyronine Regulates Survival and Differentiation of Rat Cerebellar Granule
  Neurons
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 3
year: '1992'
...
---
_id: '4305'
abstract:
- lang: eng
  text: The common shrew (Sorex araneus) is subdivided into several karyotypic races
    in Britain. Two of these races meet near Oxford to form the &quot;Oxford-Hermitage&quot;
    hybrid zone. We present a model which describes this system as a &quot;tension
    zone,&quot; i.e., a set of clines maintained by a balance between dispersal and
    selection against chromosomal heterozygotes. The Oxford and Hermitage races differ
    by Robertsonian fusions with monobrachial homology (kq, no versus ko), and so
    F1 hybrids between them would have low fertility. However, the acrocentric karyotype
    is found at high frequency within the hybrid zone, so that complex Robertsonian
    heterozygotes (kq no/q ko n) are replaced by more fertile combinations, such as
    (kq no/k q n o). This suggests that the hybrid zone has been modified so as to
    increase hybrid fitness. Mathematical analysis and simulation show that, if selection
    against complex heterozygotes is sufficiently strong relative to selection against
    simple heterozygotes, acrocentrics increase, and displace the clines for kq and
    no from the cline for ko. Superimposed on this separation is a tendency for the
    hybrid zone to move m favor of the Oxford (kq no) race. We compare the model with
    estimates of linkage disequilibrium and cline shape made from field data.
acknowledgement: 'This study was funded by grants from the Royal Society of London
  to J.B.S., and from the S.E.R.C., N.E.R.C. and the Darwin Trust to N.Barton. A.J.Reilly,
  Y.Luo, and S. J.Mercer provided unpublished data and D.Currie, A.E.Douglas, K.  S.Jackson,
  X.Lambin and D.Kapan made helpful comments on the manuscript. We appreciate our
  discussions with B. O.Bengtsson. '
article_processing_charge: No
article_type: original
author:
- first_name: Todd
  full_name: Hatfield, Todd
  last_name: Hatfield
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
- first_name: Jeremy
  full_name: Searle, Jeremy
  last_name: Searle
citation:
  ama: Hatfield T, Barton NH, Searle J. A model of a hybrid zone between two chromosomal
    races of the common shrew (Sorex araneus). <i>Evolution; International Journal
    of Organic Evolution</i>. 1992;46(4):1129-1145. doi:<a href="https://doi.org/10.1111/j.1558-5646.1992.tb00624.x">10.1111/j.1558-5646.1992.tb00624.x</a>
  apa: Hatfield, T., Barton, N. H., &#38; Searle, J. (1992). A model of a hybrid zone
    between two chromosomal races of the common shrew (Sorex araneus). <i>Evolution;
    International Journal of Organic Evolution</i>. Wiley-Blackwell. <a href="https://doi.org/10.1111/j.1558-5646.1992.tb00624.x">https://doi.org/10.1111/j.1558-5646.1992.tb00624.x</a>
  chicago: Hatfield, Todd, Nicholas H Barton, and Jeremy Searle. “A Model of a Hybrid
    Zone between Two Chromosomal Races of the Common Shrew (Sorex Araneus).” <i>Evolution;
    International Journal of Organic Evolution</i>. Wiley-Blackwell, 1992. <a href="https://doi.org/10.1111/j.1558-5646.1992.tb00624.x">https://doi.org/10.1111/j.1558-5646.1992.tb00624.x</a>.
  ieee: T. Hatfield, N. H. Barton, and J. Searle, “A model of a hybrid zone between
    two chromosomal races of the common shrew (Sorex araneus),” <i>Evolution; International
    Journal of Organic Evolution</i>, vol. 46, no. 4. Wiley-Blackwell, pp. 1129–1145,
    1992.
  ista: Hatfield T, Barton NH, Searle J. 1992. A model of a hybrid zone between two
    chromosomal races of the common shrew (Sorex araneus). Evolution; International
    Journal of Organic Evolution. 46(4), 1129–1145.
  mla: Hatfield, Todd, et al. “A Model of a Hybrid Zone between Two Chromosomal Races
    of the Common Shrew (Sorex Araneus).” <i>Evolution; International Journal of Organic
    Evolution</i>, vol. 46, no. 4, Wiley-Blackwell, 1992, pp. 1129–45, doi:<a href="https://doi.org/10.1111/j.1558-5646.1992.tb00624.x">10.1111/j.1558-5646.1992.tb00624.x</a>.
  short: T. Hatfield, N.H. Barton, J. Searle, Evolution; International Journal of
    Organic Evolution 46 (1992) 1129–1145.
date_created: 2018-12-11T12:08:09Z
date_published: 1992-08-01T00:00:00Z
date_updated: 2022-03-15T14:49:26Z
day: '01'
doi: 10.1111/j.1558-5646.1992.tb00624.x
extern: '1'
external_id:
  pmid:
  - '28564402'
intvolume: '        46'
issue: '4'
language:
- iso: eng
main_file_link:
- url: http://www.jstor.org/stable/2409761
month: '08'
oa_version: Published Version
page: 1129 - 1145
pmid: 1
publication: Evolution; International Journal of Organic Evolution
publication_identifier:
  eissn:
  - 1558-5646
  issn:
  - 0014-3820
publication_status: published
publisher: Wiley-Blackwell
publist_id: '1759'
quality_controlled: '1'
status: public
title: A model of a hybrid zone between two chromosomal races of the common shrew
  (Sorex araneus)
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 46
year: '1992'
...
---
_id: '4306'
article_processing_charge: No
author:
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
- first_name: Nick
  full_name: Goldman, Nick
  last_name: Goldman
citation:
  ama: Barton NH, Goldman N. Genetics and geography. <i>Nature</i>. 1992;357:440-441.
    doi:<a href="https://doi.org/10.1038/357440a0">10.1038/357440a0</a>
  apa: Barton, N. H., &#38; Goldman, N. (1992). Genetics and geography. <i>Nature</i>.
    Nature Publishing Group. <a href="https://doi.org/10.1038/357440a0">https://doi.org/10.1038/357440a0</a>
  chicago: Barton, Nicholas H, and Nick Goldman. “Genetics and Geography.” <i>Nature</i>.
    Nature Publishing Group, 1992. <a href="https://doi.org/10.1038/357440a0">https://doi.org/10.1038/357440a0</a>.
  ieee: N. H. Barton and N. Goldman, “Genetics and geography,” <i>Nature</i>, vol.
    357. Nature Publishing Group, pp. 440–441, 1992.
  ista: Barton NH, Goldman N. 1992. Genetics and geography. Nature. 357, 440–441.
  mla: Barton, Nicholas H., and Nick Goldman. “Genetics and Geography.” <i>Nature</i>,
    vol. 357, Nature Publishing Group, 1992, pp. 440–41, doi:<a href="https://doi.org/10.1038/357440a0">10.1038/357440a0</a>.
  short: N.H. Barton, N. Goldman, Nature 357 (1992) 440–441.
date_created: 2018-12-11T12:08:10Z
date_published: 1992-06-11T00:00:00Z
date_updated: 2022-03-15T14:27:10Z
day: '11'
doi: 10.1038/357440a0
extern: '1'
intvolume: '       357'
language:
- iso: eng
main_file_link:
- url: https://www.nature.com/articles/357440a0
month: '06'
oa_version: None
page: 440 - 441
publication: Nature
publication_status: published
publisher: Nature Publishing Group
publist_id: '1758'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Genetics and geography
type: review
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 357
year: '1992'
...
---
_id: '4307'
article_processing_charge: No
author:
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
citation:
  ama: 'Barton NH. The genetic consequences of dispersal. In: Stenseth N, Lidicker
    W, eds. <i>Animal Dispersal: Small Mammals as a Model</i>. Chapman Hall; 1992:37-60.
    doi:<a href="https://doi.org/10.1007/978-94-011-2338-9_3">10.1007/978-94-011-2338-9_3</a>'
  apa: 'Barton, N. H. (1992). The genetic consequences of dispersal. In N. Stenseth
    &#38; W. Lidicker (Eds.), <i>Animal dispersal: small mammals as a model</i> (pp.
    37–60). Chapman Hall. <a href="https://doi.org/10.1007/978-94-011-2338-9_3">https://doi.org/10.1007/978-94-011-2338-9_3</a>'
  chicago: 'Barton, Nicholas H. “The Genetic Consequences of Dispersal.” In <i>Animal
    Dispersal: Small Mammals as a Model</i>, edited by Nils Stenseth and William Lidicker,
    37–60. Chapman Hall, 1992. <a href="https://doi.org/10.1007/978-94-011-2338-9_3">https://doi.org/10.1007/978-94-011-2338-9_3</a>.'
  ieee: 'N. H. Barton, “The genetic consequences of dispersal,” in <i>Animal dispersal:
    small mammals as a model</i>, N. Stenseth and W. Lidicker, Eds. Chapman Hall,
    1992, pp. 37–60.'
  ista: 'Barton NH. 1992.The genetic consequences of dispersal. In: Animal dispersal:
    small mammals as a model. , 37–60.'
  mla: 'Barton, Nicholas H. “The Genetic Consequences of Dispersal.” <i>Animal Dispersal:
    Small Mammals as a Model</i>, edited by Nils Stenseth and William Lidicker, Chapman
    Hall, 1992, pp. 37–60, doi:<a href="https://doi.org/10.1007/978-94-011-2338-9_3">10.1007/978-94-011-2338-9_3</a>.'
  short: 'N.H. Barton, in:, N. Stenseth, W. Lidicker (Eds.), Animal Dispersal: Small
    Mammals as a Model, Chapman Hall, 1992, pp. 37–60.'
date_created: 2018-12-11T12:08:10Z
date_published: 1992-01-01T00:00:00Z
date_updated: 2022-03-14T14:19:36Z
day: '01'
doi: 10.1007/978-94-011-2338-9_3
editor:
- first_name: Nils
  full_name: Stenseth, Nils
  last_name: Stenseth
- first_name: William
  full_name: Lidicker, William
  last_name: Lidicker
extern: '1'
language:
- iso: eng
main_file_link:
- url: https://link.springer.com/chapter/10.1007/978-94-011-2338-9_3
month: '01'
oa_version: None
page: 37 - 60
publication: 'Animal dispersal: small mammals as a model'
publication_status: published
publisher: Chapman Hall
publist_id: '1757'
quality_controlled: '1'
status: public
title: The genetic consequences of dispersal
type: book_chapter
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
year: '1992'
...
---
_id: '4308'
acknowledgement: This work was supported by the Darwin Trust, NSF  grant BSR/866548,
  and SERC grant GR/E/08507. Valuable comments on the manuscript were received  from
  D. Currie, K. Dawson, K. S. Jackson, W. G. Hill,  M. Turelli, and an anonymous referee.
  I would particularly like to thank K. Dawson and the referee, for  pointing out
  the complexities involved in calculating  P(i, j; k), and J. F. Crow, for supplying
  detailed simulation results, and for his helpful comments on the draft of this paper.
article_processing_charge: No
article_type: original
author:
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
citation:
  ama: Barton NH. On the spread of new gene combinations in the third phase of Wright’s
    shifting balance. <i>Evolution; International Journal of Organic Evolution</i>.
    1992;46(2):551-557.
  apa: Barton, N. H. (1992). On the spread of new gene combinations in the third phase
    of Wright’s shifting balance. <i>Evolution; International Journal of Organic Evolution</i>.
    Wiley-Blackwell.
  chicago: Barton, Nicholas H. “On the Spread of New Gene Combinations in the Third
    Phase of Wright’s Shifting Balance.” <i>Evolution; International Journal of Organic
    Evolution</i>. Wiley-Blackwell, 1992.
  ieee: N. H. Barton, “On the spread of new gene combinations in the third phase of
    Wright’s shifting balance,” <i>Evolution; International Journal of Organic Evolution</i>,
    vol. 46, no. 2. Wiley-Blackwell, pp. 551–557, 1992.
  ista: Barton NH. 1992. On the spread of new gene combinations in the third phase
    of Wright’s shifting balance. Evolution; International Journal of Organic Evolution.
    46(2), 551–557.
  mla: Barton, Nicholas H. “On the Spread of New Gene Combinations in the Third Phase
    of Wright’s Shifting Balance.” <i>Evolution; International Journal of Organic
    Evolution</i>, vol. 46, no. 2, Wiley-Blackwell, 1992, pp. 551–57.
  short: N.H. Barton, Evolution; International Journal of Organic Evolution 46 (1992)
    551–557.
date_created: 2018-12-11T12:08:10Z
date_published: 1992-04-01T00:00:00Z
date_updated: 2022-03-14T13:36:15Z
day: '01'
extern: '1'
intvolume: '        46'
issue: '2'
language:
- iso: eng
main_file_link:
- url: http://www.jstor.org/stable/2409871
month: '04'
oa_version: None
page: 551 - 557
publication: Evolution; International Journal of Organic Evolution
publication_identifier:
  eissn:
  - 1558-5646
  issn:
  - 0014-3820
publication_status: published
publisher: Wiley-Blackwell
publist_id: '1756'
quality_controlled: '1'
status: public
title: On the spread of new gene combinations in the third phase of Wright's shifting
  balance
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 46
year: '1992'
...
---
_id: '4504'
abstract:
- lang: eng
  text: "Real-time systems operate in “real,” continuous time and state changes may
    occur at any real-numbered time point. Yet many verification methods are based
    on the assumption that states are observed at integer time points only. What can
    we conclude if a real-time system has been shown “correct” for integral observations?\r\n\r\nInteger
    time verification techniques suffice if the problem of whether all real-numbered
    behaviors of a system satisfy a property can be reduced to the question of whether
    the integral observations satisfy a (possibly modified) property. We show that
    this reduction is possible for a large and important class of systems and properties:
    the class of systems includes all systems that can be modeled as timed transition
    systems; the class of properties includes time-bounded invariance and time-bounded
    response."
acknowledgement: "A full version of this paper (including all proofs) is available
  as a technical report from Cornell University and Stanford University. The research
  was supported in part by the National Science Foundation under grants CCR-89-11512
  and CCR-89-13641, by the Defense Advanced Research Projects Agency under contract
  NAG2-703, by the United States Air Force Office of Scientific Research under contract
  AFOSR-90-0057, and by the European Community ESPRIT Basic Research Action Project
  3096 (SPEC).\r\n\r\nSponsors: National Science Foundation grant CCR-89-11512,  National
  Science Foundation grant CCR-89-13641, Defense Advanced Research Projects Agency
  contract NAG2-703, United States Air Force Office of Scientific Research contract
  AFOSR-90-0057, European Community ESPRIT Basic Research Action Project 3096 (SPEC).\r\n"
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000−0002−2985−7724
- first_name: Zohar
  full_name: Manna, Zohar
  last_name: Manna
- first_name: Amir
  full_name: Pnueli, Amir
  last_name: Pnueli
citation:
  ama: 'Henzinger TA, Manna Z, Pnueli A. What good are digital clocks? In: <i>19th
    International Colloquium on Automata, Languages and Programming</i>. Vol 623.
    Springer; 1992:545-558. doi:<a href="https://doi.org/10.1007/3-540-55719-9_103">10.1007/3-540-55719-9_103</a>'
  apa: 'Henzinger, T. A., Manna, Z., &#38; Pnueli, A. (1992). What good are digital
    clocks? In <i>19th International Colloquium on Automata, Languages and Programming</i>
    (Vol. 623, pp. 545–558). Vienna, Austria: Springer. <a href="https://doi.org/10.1007/3-540-55719-9_103">https://doi.org/10.1007/3-540-55719-9_103</a>'
  chicago: Henzinger, Thomas A, Zohar Manna, and Amir Pnueli. “What Good Are Digital
    Clocks?” In <i>19th International Colloquium on Automata, Languages and Programming</i>,
    623:545–58. Springer, 1992. <a href="https://doi.org/10.1007/3-540-55719-9_103">https://doi.org/10.1007/3-540-55719-9_103</a>.
  ieee: T. A. Henzinger, Z. Manna, and A. Pnueli, “What good are digital clocks?,”
    in <i>19th International Colloquium on Automata, Languages and Programming</i>,
    Vienna, Austria, 1992, vol. 623, pp. 545–558.
  ista: 'Henzinger TA, Manna Z, Pnueli A. 1992. What good are digital clocks? 19th
    International Colloquium on Automata, Languages and Programming. ICALP: Automata,
    Languages and Programming, LNCS, vol. 623, 545–558.'
  mla: Henzinger, Thomas A., et al. “What Good Are Digital Clocks?” <i>19th International
    Colloquium on Automata, Languages and Programming</i>, vol. 623, Springer, 1992,
    pp. 545–58, doi:<a href="https://doi.org/10.1007/3-540-55719-9_103">10.1007/3-540-55719-9_103</a>.
  short: T.A. Henzinger, Z. Manna, A. Pnueli, in:, 19th International Colloquium on
    Automata, Languages and Programming, Springer, 1992, pp. 545–558.
conference:
  end_date: 1992-07-17
  location: Vienna, Austria
  name: 'ICALP: Automata, Languages and Programming'
  start_date: 1992-07-13
date_created: 2018-12-11T12:09:11Z
date_published: 1992-01-01T00:00:00Z
date_updated: 2022-03-14T09:47:09Z
day: '01'
doi: 10.1007/3-540-55719-9_103
extern: '1'
intvolume: '       623'
language:
- iso: eng
main_file_link:
- url: https://link.springer.com/chapter/10.1007/3-540-55719-9_103
month: '01'
oa_version: None
page: 545 - 558
publication: 19th International Colloquium on Automata, Languages and Programming
publication_status: published
publisher: Springer
publist_id: '223'
quality_controlled: '1'
status: public
title: What good are digital clocks?
type: conference
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 623
year: '1992'
...
---
_id: '4505'
abstract:
- lang: eng
  text: "We describe finite-state programs over real-numbered time in a guarded-command
    language with real-valued clocks or, equivalently, as finite automata with real-valued
    clocks. Model checking answers the question which states of a real-time program
    satisfy a branching-time specification (given in an extension of CTL with clock
    variables). We develop an algorithm that computes this set of states symbolically
    as a fixpoint of a functional on state predicates, without constructing the state
    space.\r\n\r\nFor this purpose, we introduce a mu-calculus on computation trees
    over real-numbered time. Unfortunately, many standard program properties, such
    as response for all nonzeno execution sequences (during which time diverges),
    cannot be characterized by fixpoints: we show that the expressiveness of the timed
    mu-calculus is incomparable to the expressiveness of timed CTL. Fortunately, this
    result does not impair the symbolic verification of &quot;implementable&quot;
    real-time programs--those whose safety constraints are machine-closed with respect
    to diverging time and whose fairness constraints are restricted to finite upper
    bounds on clock values. All timed CTL properties of such programs are shown to
    be computable as finitely approximable fixpoints in a simple decidable theory."
article_processing_charge: No
author:
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000−0002−2985−7724
- first_name: Xavier
  full_name: Nicollin, Xavier
  last_name: Nicollin
- first_name: Joseph
  full_name: Sifakis, Joseph
  last_name: Sifakis
- first_name: Sergio
  full_name: Yovine, Sergio
  last_name: Yovine
citation:
  ama: 'Henzinger TA, Nicollin X, Sifakis J, Yovine S. Symbolic model checking for
    real-time systems. In: <i>Proceedings of the 7th Annual IEEE Symposium on Logic
    in Computer Science</i>. IEEE; 1992:394-406. doi:<a href="https://doi.org/10.1109/LICS.1992.185551">10.1109/LICS.1992.185551</a>'
  apa: 'Henzinger, T. A., Nicollin, X., Sifakis, J., &#38; Yovine, S. (1992). Symbolic
    model checking for real-time systems. In <i>Proceedings of the 7th Annual IEEE
    Symposium on Logic in Computer Science</i> (pp. 394–406). Santa Cruz, CA, United
    States of America: IEEE. <a href="https://doi.org/10.1109/LICS.1992.185551">https://doi.org/10.1109/LICS.1992.185551</a>'
  chicago: Henzinger, Thomas A, Xavier Nicollin, Joseph Sifakis, and Sergio Yovine.
    “Symbolic Model Checking for Real-Time Systems.” In <i>Proceedings of the 7th
    Annual IEEE Symposium on Logic in Computer Science</i>, 394–406. IEEE, 1992. <a
    href="https://doi.org/10.1109/LICS.1992.185551">https://doi.org/10.1109/LICS.1992.185551</a>.
  ieee: T. A. Henzinger, X. Nicollin, J. Sifakis, and S. Yovine, “Symbolic model checking
    for real-time systems,” in <i>Proceedings of the 7th Annual IEEE Symposium on
    Logic in Computer Science</i>, Santa Cruz, CA, United States of America, 1992,
    pp. 394–406.
  ista: 'Henzinger TA, Nicollin X, Sifakis J, Yovine S. 1992. Symbolic model checking
    for real-time systems. Proceedings of the 7th Annual IEEE Symposium on Logic in
    Computer Science. LICS: Logic in Computer Science, 394–406.'
  mla: Henzinger, Thomas A., et al. “Symbolic Model Checking for Real-Time Systems.”
    <i>Proceedings of the 7th Annual IEEE Symposium on Logic in Computer Science</i>,
    IEEE, 1992, pp. 394–406, doi:<a href="https://doi.org/10.1109/LICS.1992.185551">10.1109/LICS.1992.185551</a>.
  short: T.A. Henzinger, X. Nicollin, J. Sifakis, S. Yovine, in:, Proceedings of the
    7th Annual IEEE Symposium on Logic in Computer Science, IEEE, 1992, pp. 394–406.
conference:
  end_date: 1992-06-25
  location: Santa Cruz, CA, United States of America
  name: 'LICS: Logic in Computer Science'
  start_date: 1992-06-22
date_created: 2018-12-11T12:09:12Z
date_published: 1992-01-01T00:00:00Z
date_updated: 2022-03-14T13:20:50Z
day: '01'
doi: 10.1109/LICS.1992.185551
extern: '1'
language:
- iso: eng
main_file_link:
- url: https://ieeexplore.ieee.org/document/185551
month: '01'
oa_version: None
page: 394 - 406
publication: Proceedings of the 7th Annual IEEE Symposium on Logic in Computer Science
publication_identifier:
  isbn:
  - 0-8186-2735-2
publication_status: published
publisher: IEEE
publist_id: '224'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Symbolic model checking for real-time systems
type: conference
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
year: '1992'
...
---
_id: '4507'
abstract:
- lang: eng
  text: We incorporate time into an interleaving model of concurrency. In timed transition
    systems, the qualitative fairness requirements of traditional transition system
    are replaced (and superseded) by quantitative lower-bound and upperbound timing
    constraints on transitions. The purpose of this paper is to explore the scope
    of applicability for the abstract model of timed transition systems. We demonstrate
    that the model can represent a wide variety of phenomena that routinely occur
    in conjunction with the timed execution of concurrent processes. Our treatment
    covers both processes that are executed in parallel on separate processors and
    communicate either through shared variables or by message passing, and processes
    that time-share a limited number of processors under a given scheduling policy.
    Often it is this scheduling policy that determines if a system meets its real-time
    requirements. Thus we explicitly address such questions as time-outs, interrupts,
    static and dynamic priorities.
acknowledgement: 'Sponsor: IBM graduate fellowship, National Science Foundation grant
  CCR-89-11512 National Science Foundation grant CCR-89-13641,  Defense Advanced Research
  Projects Agency contract N00039-84-C-0211, United States Air Force Office of Scientific
  Research under contract AFOSR-90-0057,  European Community ESPRIT Basic Research
  Action project 3096 (SPEC)'
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000−0002−2985−7724
- first_name: Zohar
  full_name: Manna, Zohar
  last_name: Manna
- first_name: Amir
  full_name: Pnueli, Amir
  last_name: Pnueli
citation:
  ama: 'Henzinger TA, Manna Z, Pnueli A. Timed transition systems. In: <i>Real Time:
    Theory in Practice</i>. Vol 600. Springer; 1992:226-251. doi:<a href="https://doi.org/10.1007/BFb0031995">10.1007/BFb0031995</a>'
  apa: 'Henzinger, T. A., Manna, Z., &#38; Pnueli, A. (1992). Timed transition systems.
    In <i>Real Time: Theory in Practice</i> (Vol. 600, pp. 226–251). Springer. <a
    href="https://doi.org/10.1007/BFb0031995">https://doi.org/10.1007/BFb0031995</a>'
  chicago: 'Henzinger, Thomas A, Zohar Manna, and Amir Pnueli. “Timed Transition Systems.”
    In <i>Real Time: Theory in Practice</i>, 600:226–51. Springer, 1992. <a href="https://doi.org/10.1007/BFb0031995">https://doi.org/10.1007/BFb0031995</a>.'
  ieee: 'T. A. Henzinger, Z. Manna, and A. Pnueli, “Timed transition systems,” in
    <i>Real Time: Theory in Practice</i>, vol. 600, Springer, 1992, pp. 226–251.'
  ista: 'Henzinger TA, Manna Z, Pnueli A. 1992.Timed transition systems. In: Real
    Time: Theory in Practice. LNCS, vol. 600, 226–251.'
  mla: 'Henzinger, Thomas A., et al. “Timed Transition Systems.” <i>Real Time: Theory
    in Practice</i>, vol. 600, Springer, 1992, pp. 226–51, doi:<a href="https://doi.org/10.1007/BFb0031995">10.1007/BFb0031995</a>.'
  short: 'T.A. Henzinger, Z. Manna, A. Pnueli, in:, Real Time: Theory in Practice,
    Springer, 1992, pp. 226–251.'
date_created: 2018-12-11T12:09:12Z
date_published: 1992-01-01T00:00:00Z
date_updated: 2022-03-14T09:34:44Z
day: '01'
doi: 10.1007/BFb0031995
extern: '1'
intvolume: '       600'
language:
- iso: eng
main_file_link:
- url: https://link.springer.com/chapter/10.1007/BFb0031995
month: '01'
oa_version: None
page: 226 - 251
publication: 'Real Time: Theory in Practice'
publication_status: published
publisher: Springer
publist_id: '222'
status: public
title: Timed transition systems
type: book_chapter
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 600
year: '1992'
...
---
_id: '4517'
abstract:
- lang: eng
  text: It has been observed repeatedly that the standard safety-liveness classification
    for properties of reactive systems does not fit for real-time properties. This
    is because the implicit “liveliness” of time shifts the spectrum towards the safety
    side. While, for example, response—that “something good” will happen eventually—is
    a classical liveness property, bounded response—that “something good” will happen
    soon, within a certain amount of time—has many characteristics of safety. We account
    for this phenomenon formally by defining safety and liveness relative to a given
    condition, such as the progress of time.
acknowledgement: 'The author thanks Martin Abadi, Rajeev Alur, David Dill, Leslie
  Lamport, Zohar Manna, Amir Pnueli, Fred Schneider, and two anonymous referees for
  many valuable suggestions and improvements. '
article_processing_charge: No
article_type: original
author:
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000−0002−2985−7724
citation:
  ama: Henzinger TA. Sooner Is Safer Than Later. <i>Information Processing Letters</i>.
    1992;43(3):135-141. doi:<a href="https://doi.org/10.1016/0020-0190(92)90005-G">10.1016/0020-0190(92)90005-G</a>
  apa: Henzinger, T. A. (1992). Sooner Is Safer Than Later. <i>Information Processing
    Letters</i>. Elsevier. <a href="https://doi.org/10.1016/0020-0190(92)90005-G">https://doi.org/10.1016/0020-0190(92)90005-G</a>
  chicago: Henzinger, Thomas A. “Sooner Is Safer Than Later.” <i>Information Processing
    Letters</i>. Elsevier, 1992. <a href="https://doi.org/10.1016/0020-0190(92)90005-G">https://doi.org/10.1016/0020-0190(92)90005-G</a>.
  ieee: T. A. Henzinger, “Sooner Is Safer Than Later,” <i>Information Processing Letters</i>,
    vol. 43, no. 3. Elsevier, pp. 135–141, 1992.
  ista: Henzinger TA. 1992. Sooner Is Safer Than Later. Information Processing Letters.
    43(3), 135–141.
  mla: Henzinger, Thomas A. “Sooner Is Safer Than Later.” <i>Information Processing
    Letters</i>, vol. 43, no. 3, Elsevier, 1992, pp. 135–41, doi:<a href="https://doi.org/10.1016/0020-0190(92)90005-G">10.1016/0020-0190(92)90005-G</a>.
  short: T.A. Henzinger, Information Processing Letters 43 (1992) 135–141.
date_created: 2018-12-11T12:09:16Z
date_published: 1992-09-14T00:00:00Z
date_updated: 2022-03-07T11:31:23Z
day: '14'
doi: 10.1016/0020-0190(92)90005-G
extern: '1'
intvolume: '        43'
issue: '3'
language:
- iso: eng
main_file_link:
- url: https://www.sciencedirect.com/science/article/pii/002001909290005G?via%3Dihub
month: '09'
oa_version: None
page: 135 - 141
publication: Information Processing Letters
publication_identifier:
  issn:
  - 0020-0190
publication_status: published
publisher: Elsevier
publist_id: '211'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Sooner Is Safer Than Later
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 43
year: '1992'
...
---
_id: '2482'
abstract:
- lang: eng
  text: The complementary DNA of a metabotropic glutamate receptor coupled to inositol
    phosphate/Ca2+ signal transduction has been cloned and characterized. This receptor
    shows no sequence similarity to conventional G protein-coupled receptors and has
    a unique structure with large hydrophilic sequences at both sides of seven putative
    membrane-spanning domains. Abundant expression of this messenger RNA is observed
    in neuronal cells in hippocampal dentate gyrus and CA2-3 and in cerebellar Purkinje
    cells, suggesting the importance of this receptor in specific hippocampal and
    cerebellar functions.
article_processing_charge: No
article_type: original
author:
- first_name: Masayuki
  full_name: Masu, Masayuki
  last_name: Masu
- first_name: Yasuto
  full_name: Tanabe, Yasuto
  last_name: Tanabe
- first_name: Kunihiro
  full_name: Tsuchida, Kunihiro
  last_name: Tsuchida
- first_name: Ryuichi
  full_name: Shigemoto, Ryuichi
  id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
  last_name: Shigemoto
  orcid: 0000-0001-8761-9444
- first_name: Shigetada
  full_name: Nakanishi, Shigetada
  last_name: Nakanishi
citation:
  ama: Masu M, Tanabe Y, Tsuchida K, Shigemoto R, Nakanishi S. Sequence and expression
    of a metabotropic glutamate receptor. <i>Nature</i>. 1991;349(6312):760-765. doi:<a
    href="https://doi.org/10.1038/349760a0">10.1038/349760a0</a>
  apa: Masu, M., Tanabe, Y., Tsuchida, K., Shigemoto, R., &#38; Nakanishi, S. (1991).
    Sequence and expression of a metabotropic glutamate receptor. <i>Nature</i>. Nature
    Publishing Group. <a href="https://doi.org/10.1038/349760a0">https://doi.org/10.1038/349760a0</a>
  chicago: Masu, Masayuki, Yasuto Tanabe, Kunihiro Tsuchida, Ryuichi Shigemoto, and
    Shigetada Nakanishi. “Sequence and Expression of a Metabotropic Glutamate Receptor.”
    <i>Nature</i>. Nature Publishing Group, 1991. <a href="https://doi.org/10.1038/349760a0">https://doi.org/10.1038/349760a0</a>.
  ieee: M. Masu, Y. Tanabe, K. Tsuchida, R. Shigemoto, and S. Nakanishi, “Sequence
    and expression of a metabotropic glutamate receptor,” <i>Nature</i>, vol. 349,
    no. 6312. Nature Publishing Group, pp. 760–765, 1991.
  ista: Masu M, Tanabe Y, Tsuchida K, Shigemoto R, Nakanishi S. 1991. Sequence and
    expression of a metabotropic glutamate receptor. Nature. 349(6312), 760–765.
  mla: Masu, Masayuki, et al. “Sequence and Expression of a Metabotropic Glutamate
    Receptor.” <i>Nature</i>, vol. 349, no. 6312, Nature Publishing Group, 1991, pp.
    760–65, doi:<a href="https://doi.org/10.1038/349760a0">10.1038/349760a0</a>.
  short: M. Masu, Y. Tanabe, K. Tsuchida, R. Shigemoto, S. Nakanishi, Nature 349 (1991)
    760–765.
date_created: 2018-12-11T11:57:55Z
date_published: 1991-02-28T00:00:00Z
date_updated: 2022-03-03T15:37:36Z
day: '28'
doi: 10.1038/349760a0
extern: '1'
external_id:
  pmid:
  - '1847995 '
intvolume: '       349'
issue: '6312'
language:
- iso: eng
main_file_link:
- url: https://www.nature.com/articles/349760a0
month: '02'
oa_version: None
page: 760 - 765
pmid: 1
publication: Nature
publication_identifier:
  eissn:
  - 1476-4687
  issn:
  - 0028-0836
publication_status: published
publisher: Nature Publishing Group
publist_id: '4419'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Sequence and expression of a metabotropic glutamate receptor
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 349
year: '1991'
...
---
_id: '2483'
abstract:
- lang: eng
  text: A complementary DNA encoding the rat NMDA receptor has been cloned and characterized.
    The single protein encoded by the cDNA forms a receptor-channel complex that has
    electrophysiological and pharmacological properties characteristic of the NMDA
    receptor. This protein has a significant sequence similarity to the AMPA/kainate
    receptors and contains four putative transmembrane segments following a large
    extracellular domain. The NMDA receptor messenger RNA is expressed in neuronal
    cells throughout the brain regions, particularly in the hippocampus, cerebral
    cortex and cerebellum.
article_processing_charge: No
article_type: original
author:
- first_name: Koki
  full_name: Moriyoshi, Koki
  last_name: Moriyoshi
- first_name: Masayuki
  full_name: Masu, Masayuki
  last_name: Masu
- first_name: Takahiro
  full_name: Ishii, Takahiro
  last_name: Ishii
- first_name: Ryuichi
  full_name: Shigemoto, Ryuichi
  id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
  last_name: Shigemoto
  orcid: 0000-0001-8761-9444
- first_name: Noboru
  full_name: Mizuno, Noboru
  last_name: Mizuno
- first_name: Shigetada
  full_name: Nakanishi, Shigetada
  last_name: Nakanishi
citation:
  ama: Moriyoshi K, Masu M, Ishii T, Shigemoto R, Mizuno N, Nakanishi S. Molecular
    cloning and characterization of the rat NMDA receptor. <i>Nature</i>. 1991;353(6348):31-37.
    doi:<a href="https://doi.org/10.1038/354031a0">10.1038/354031a0</a>
  apa: Moriyoshi, K., Masu, M., Ishii, T., Shigemoto, R., Mizuno, N., &#38; Nakanishi,
    S. (1991). Molecular cloning and characterization of the rat NMDA receptor. <i>Nature</i>.
    Nature Publishing Group. <a href="https://doi.org/10.1038/354031a0">https://doi.org/10.1038/354031a0</a>
  chicago: Moriyoshi, Koki, Masayuki Masu, Takahiro Ishii, Ryuichi Shigemoto, Noboru
    Mizuno, and Shigetada Nakanishi. “Molecular Cloning and Characterization of the
    Rat NMDA Receptor.” <i>Nature</i>. Nature Publishing Group, 1991. <a href="https://doi.org/10.1038/354031a0">https://doi.org/10.1038/354031a0</a>.
  ieee: K. Moriyoshi, M. Masu, T. Ishii, R. Shigemoto, N. Mizuno, and S. Nakanishi,
    “Molecular cloning and characterization of the rat NMDA receptor,” <i>Nature</i>,
    vol. 353, no. 6348. Nature Publishing Group, pp. 31–37, 1991.
  ista: Moriyoshi K, Masu M, Ishii T, Shigemoto R, Mizuno N, Nakanishi S. 1991. Molecular
    cloning and characterization of the rat NMDA receptor. Nature. 353(6348), 31–37.
  mla: Moriyoshi, Koki, et al. “Molecular Cloning and Characterization of the Rat
    NMDA Receptor.” <i>Nature</i>, vol. 353, no. 6348, Nature Publishing Group, 1991,
    pp. 31–37, doi:<a href="https://doi.org/10.1038/354031a0">10.1038/354031a0</a>.
  short: K. Moriyoshi, M. Masu, T. Ishii, R. Shigemoto, N. Mizuno, S. Nakanishi, Nature
    353 (1991) 31–37.
date_created: 2018-12-11T11:57:56Z
date_published: 1991-11-07T00:00:00Z
date_updated: 2022-03-03T15:25:04Z
day: '07'
doi: 10.1038/354031a0
extern: '1'
external_id:
  pmid:
  - '1834949'
intvolume: '       353'
issue: '6348'
language:
- iso: eng
main_file_link:
- url: https://www.nature.com/articles/354031a0
month: '11'
oa_version: None
page: 31 - 37
pmid: 1
publication: Nature
publication_identifier:
  eissn:
  - 1476-4687
  issn:
  - 0028-0836
publication_status: published
publisher: Nature Publishing Group
publist_id: '4418'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Molecular cloning and characterization of the rat NMDA receptor
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 353
year: '1991'
...
---
_id: '2529'
abstract:
- lang: eng
  text: 'The distribution of cerebral cortical neurons sending projection fibers to
    the nucleus of the solitary tract (NST), and the topographical distribution of
    axon terminals of cortico-NST fibers within the NST were examined in the cat by
    two sets of experiments with horseradish peroxidase (HRP) and HRP conjugated with
    wheat germ agglutinin (WGA-HRP). First, HRP was injected into the NST. In the
    cerebral cortex of these cats, neuronal cell bodies were labeled retrogradely
    in the deep pyramidal cell layer (layer V): After HRP injection centered on the
    rostral or middle part of the NST, HRP-labeled neuronal cell bodies were distributed
    mainly in the orbital gyrus and caudal part of the intralimbic cortex, and additionally
    in the rostral part of the anterior sylvian gyrus. After HRP injection centered
    on the caudal part of the NST, labeled neuronal cell bodies were seen mainly in
    the caudoventral part of the intralimbic cortex, and additionally in the orbital
    gyrus, posterior sigmoid gyrus and rostral part of the anterior sylvian gyrus.
    The labeling in the intralimbic cortex, orbital gyrus and anterior sylvian gyrus
    was bilateral with a predominantly ipsilateral distribution, while that in the
    posterior sigmoid gyrus was bilateral with a clear-cut contralateral dominance.
    In the second set of experiments, WGA-HRP was injected into the cerebral cortical
    regions where neuronal cell bodies had been retrogradely labeled with HRP injected
    into the NST: after WGA-HRP injection into the orbital gyrus, presumed axon terminals
    in the NST were labeled in the rostral two thirds of the nucleus bilaterally with
    an ipsilateral predominance. After WGA-HRP injection into the rostral part of
    the anterior sylvian gyrus, a moderate number of presumed axon terminals were
    labeled throughout the whole rostrocaudal extent of the NST bilaterally with a
    slight ipsilateral dominance. After WGA-HRP injection into the middle and caudal
    parts of the anterior sylvian gyrus, no labeling was found in the NST. After WGA-HRP
    injection into the caudal part of the intralimbic cortex, presumed terminal labeling
    in the NST was seen throughout the whole rostrocaudal extent of the nucleus bilaterally
    with a dominant ipsilateral distribution. After WGA-HRP injection into the posterior
    sigmoid gyrus, however, no terminal labeling was found in the NST. The results
    indicate that cortico-NST fibers from the orbital gyrus terminate in the rostral
    two thirds of the NST, while those from the intralimbic cortex and the rostral
    part of the anterior sylvian gyrus project to the whole rostrocaudal extent of
    the NST.'
article_processing_charge: No
article_type: original
author:
- first_name: Yukihiko
  full_name: Yasui, Yukihiko
  last_name: Yasui
- first_name: Kazuo
  full_name: Itoh, Kazuo
  last_name: Itoh
- first_name: Takeshi
  full_name: Kaneko, Takeshi
  last_name: Kaneko
- first_name: Ryuichi
  full_name: Shigemoto, Ryuichi
  id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
  last_name: Shigemoto
  orcid: 0000-0001-8761-9444
- first_name: Noboru
  full_name: Mizuno, Noboru
  last_name: Mizuno
citation:
  ama: Yasui Y, Itoh K, Kaneko T, Shigemoto R, Mizuno N. Topographical projections
    from the cerebral cortex to the nucleus of the solitary tract in the cat. <i>Experimental
    Brain Research</i>. 1991;85(1):75-84. doi:<a href="https://doi.org/10.1007/BF00229988">10.1007/BF00229988</a>
  apa: Yasui, Y., Itoh, K., Kaneko, T., Shigemoto, R., &#38; Mizuno, N. (1991). Topographical
    projections from the cerebral cortex to the nucleus of the solitary tract in the
    cat. <i>Experimental Brain Research</i>. Springer. <a href="https://doi.org/10.1007/BF00229988">https://doi.org/10.1007/BF00229988</a>
  chicago: Yasui, Yukihiko, Kazuo Itoh, Takeshi Kaneko, Ryuichi Shigemoto, and Noboru
    Mizuno. “Topographical Projections from the Cerebral Cortex to the Nucleus of
    the Solitary Tract in the Cat.” <i>Experimental Brain Research</i>. Springer,
    1991. <a href="https://doi.org/10.1007/BF00229988">https://doi.org/10.1007/BF00229988</a>.
  ieee: Y. Yasui, K. Itoh, T. Kaneko, R. Shigemoto, and N. Mizuno, “Topographical
    projections from the cerebral cortex to the nucleus of the solitary tract in the
    cat,” <i>Experimental Brain Research</i>, vol. 85, no. 1. Springer, pp. 75–84,
    1991.
  ista: Yasui Y, Itoh K, Kaneko T, Shigemoto R, Mizuno N. 1991. Topographical projections
    from the cerebral cortex to the nucleus of the solitary tract in the cat. Experimental
    Brain Research. 85(1), 75–84.
  mla: Yasui, Yukihiko, et al. “Topographical Projections from the Cerebral Cortex
    to the Nucleus of the Solitary Tract in the Cat.” <i>Experimental Brain Research</i>,
    vol. 85, no. 1, Springer, 1991, pp. 75–84, doi:<a href="https://doi.org/10.1007/BF00229988">10.1007/BF00229988</a>.
  short: Y. Yasui, K. Itoh, T. Kaneko, R. Shigemoto, N. Mizuno, Experimental Brain
    Research 85 (1991) 75–84.
date_created: 2018-12-11T11:58:12Z
date_published: 1991-05-01T00:00:00Z
date_updated: 2022-03-03T15:16:05Z
day: '01'
doi: 10.1007/BF00229988
extern: '1'
external_id:
  pmid:
  - '1715827'
intvolume: '        85'
issue: '1'
language:
- iso: eng
main_file_link:
- url: https://link.springer.com/article/10.1007/BF00229988
month: '05'
oa_version: None
page: 75 - 84
pmid: 1
publication: Experimental Brain Research
publication_identifier:
  eissn:
  - 1432-1106
  issn:
  - 0014-4819
publication_status: published
publisher: Springer
publist_id: '4370'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Topographical projections from the cerebral cortex to the nucleus of the solitary
  tract in the cat
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 85
year: '1991'
...
---
_id: '2530'
article_processing_charge: No
author:
- first_name: Shigetada
  full_name: Nakanishi, Shigetada
  last_name: Nakanishi
- first_name: Hiroaki
  full_name: Ohkubo, Hiroaki
  last_name: Ohkubo
- first_name: Akira
  full_name: Kakizuka, Akira
  last_name: Kakizuka
- first_name: Yoshifumi
  full_name: Yokota, Yoshifumi
  last_name: Yokota
- first_name: Ryuichi
  full_name: Shigemoto, Ryuichi
  id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
  last_name: Shigemoto
  orcid: 0000-0001-8761-9444
- first_name: Yoshiki
  full_name: Sasai, Yoshiki
  last_name: Sasai
- first_name: Toru
  full_name: Takumi, Toru
  last_name: Takumi
citation:
  ama: 'Nakanishi S, Ohkubo H, Kakizuka A, et al. Molecular characterization of mammalian
    tachykinin receptors and a possible epithelial potassium channel. In: <i>Recent
    Progress in Hormone Research</i>. Vol 46. The Endocrine Society; 1991:59-83. doi:<a
    href="https://doi.org/10.1016/b978-0-12-571146-3.50007-9">10.1016/b978-0-12-571146-3.50007-9</a>'
  apa: Nakanishi, S., Ohkubo, H., Kakizuka, A., Yokota, Y., Shigemoto, R., Sasai,
    Y., &#38; Takumi, T. (1991). Molecular characterization of mammalian tachykinin
    receptors and a possible epithelial potassium channel. In <i>Recent Progress in
    Hormone Research</i> (Vol. 46, pp. 59–83). The Endocrine Society. <a href="https://doi.org/10.1016/b978-0-12-571146-3.50007-9">https://doi.org/10.1016/b978-0-12-571146-3.50007-9</a>
  chicago: Nakanishi, Shigetada, Hiroaki Ohkubo, Akira Kakizuka, Yoshifumi Yokota,
    Ryuichi Shigemoto, Yoshiki Sasai, and Toru Takumi. “Molecular Characterization
    of Mammalian Tachykinin Receptors and a Possible Epithelial Potassium Channel.”
    In <i>Recent Progress in Hormone Research</i>, 46:59–83. The Endocrine Society,
    1991. <a href="https://doi.org/10.1016/b978-0-12-571146-3.50007-9">https://doi.org/10.1016/b978-0-12-571146-3.50007-9</a>.
  ieee: S. Nakanishi <i>et al.</i>, “Molecular characterization of mammalian tachykinin
    receptors and a possible epithelial potassium channel,” in <i>Recent Progress
    in Hormone Research</i>, vol. 46, The Endocrine Society, 1991, pp. 59–83.
  ista: 'Nakanishi S, Ohkubo H, Kakizuka A, Yokota Y, Shigemoto R, Sasai Y, Takumi
    T. 1991.Molecular characterization of mammalian tachykinin receptors and a possible
    epithelial potassium channel. In: Recent Progress in Hormone Research. vol. 46,
    59–83.'
  mla: Nakanishi, Shigetada, et al. “Molecular Characterization of Mammalian Tachykinin
    Receptors and a Possible Epithelial Potassium Channel.” <i>Recent Progress in
    Hormone Research</i>, vol. 46, The Endocrine Society, 1991, pp. 59–83, doi:<a
    href="https://doi.org/10.1016/b978-0-12-571146-3.50007-9">10.1016/b978-0-12-571146-3.50007-9</a>.
  short: S. Nakanishi, H. Ohkubo, A. Kakizuka, Y. Yokota, R. Shigemoto, Y. Sasai,
    T. Takumi, in:, Recent Progress in Hormone Research, The Endocrine Society, 1991,
    pp. 59–83.
date_created: 2018-12-11T11:58:13Z
date_published: 1991-01-01T00:00:00Z
date_updated: 2022-03-03T14:59:24Z
day: '01'
doi: 10.1016/b978-0-12-571146-3.50007-9
extern: '1'
external_id:
  pmid:
  - '2177908 '
intvolume: '        46'
language:
- iso: eng
main_file_link:
- url: https://www.sciencedirect.com/science/article/pii/B9780125711463500079
month: '01'
oa_version: None
page: 59 - 83
pmid: 1
publication: Recent Progress in Hormone Research
publication_identifier:
  isbn:
  - 978-0-12-571148-7
publication_status: published
publisher: The Endocrine Society
publist_id: '4369'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Molecular characterization of mammalian tachykinin receptors and a possible
  epithelial potassium channel
type: book_chapter
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 46
year: '1991'
...
---
_id: '1946'
abstract:
- lang: eng
  text: An ultra-low dose (10-14 M) of opioid peptide [D-Ala2]methionine enkephalinamide
    (DAMEA) is found to exert an inhibitory effect on the production of reactive oxygen
    species (respiratory burst) in human neutrophils. The validity of this phenomenon
    has been verified in a series of studies that comprised 30 experiments. The inhibition
    has proved to be statistically significant (P&lt;0.001). The dose-response dependence
    of the effect (10-15-10-9 M) followed a characteristic biphasic pattern (with
    the maximum effect at ultra-low doses). An opioid antagonist, naloxone partially
    blocks the inhibitory effect, which indicates that the DAMEA action is at least
    partially mediated by opioid receptors.
article_processing_charge: No
author:
- first_name: Sergei
  full_name: Zaǐtsev, Sergei
  last_name: Zaǐtsev
- first_name: Leonid A
  full_name: Sazanov, Leonid A
  id: 338D39FE-F248-11E8-B48F-1D18A9856A87
  last_name: Sazanov
  orcid: 0000-0002-0977-7989
- first_name: Aleksei
  full_name: Koshkin, Aleksei
  last_name: Koshkin
- first_name: Galina
  full_name: Sud'Ina, Galina
  last_name: Sud'Ina
- first_name: Sergei
  full_name: Varfolomeev, Sergei
  last_name: Varfolomeev
citation:
  ama: Zaǐtsev S, Sazanov LA, Koshkin A, Sud’Ina G, Varfolomeev S. Respiratory burst
    inhibition in human neutrophils by ultra-low doses of [D-Ala2] methionine enkephalinamide.
    <i>FEBS Letters</i>. 1991;291(1):84-86. doi:<a href="https://doi.org/10.1016/0014-5793(91)81109-L">10.1016/0014-5793(91)81109-L</a>
  apa: Zaǐtsev, S., Sazanov, L. A., Koshkin, A., Sud’Ina, G., &#38; Varfolomeev, S.
    (1991). Respiratory burst inhibition in human neutrophils by ultra-low doses of
    [D-Ala2] methionine enkephalinamide. <i>FEBS Letters</i>. Elsevier. <a href="https://doi.org/10.1016/0014-5793(91)81109-L">https://doi.org/10.1016/0014-5793(91)81109-L</a>
  chicago: Zaǐtsev, Sergei, Leonid A Sazanov, Aleksei Koshkin, Galina Sud’Ina, and
    Sergei Varfolomeev. “Respiratory Burst Inhibition in Human Neutrophils by Ultra-Low
    Doses of [D-Ala2] Methionine Enkephalinamide.” <i>FEBS Letters</i>. Elsevier,
    1991. <a href="https://doi.org/10.1016/0014-5793(91)81109-L">https://doi.org/10.1016/0014-5793(91)81109-L</a>.
  ieee: S. Zaǐtsev, L. A. Sazanov, A. Koshkin, G. Sud’Ina, and S. Varfolomeev, “Respiratory
    burst inhibition in human neutrophils by ultra-low doses of [D-Ala2] methionine
    enkephalinamide,” <i>FEBS Letters</i>, vol. 291, no. 1. Elsevier, pp. 84–86, 1991.
  ista: Zaǐtsev S, Sazanov LA, Koshkin A, Sud’Ina G, Varfolomeev S. 1991. Respiratory
    burst inhibition in human neutrophils by ultra-low doses of [D-Ala2] methionine
    enkephalinamide. FEBS Letters. 291(1), 84–86.
  mla: Zaǐtsev, Sergei, et al. “Respiratory Burst Inhibition in Human Neutrophils
    by Ultra-Low Doses of [D-Ala2] Methionine Enkephalinamide.” <i>FEBS Letters</i>,
    vol. 291, no. 1, Elsevier, 1991, pp. 84–86, doi:<a href="https://doi.org/10.1016/0014-5793(91)81109-L">10.1016/0014-5793(91)81109-L</a>.
  short: S. Zaǐtsev, L.A. Sazanov, A. Koshkin, G. Sud’Ina, S. Varfolomeev, FEBS Letters
    291 (1991) 84–86.
date_created: 2018-12-11T11:54:51Z
date_published: 1991-10-07T00:00:00Z
date_updated: 2022-03-07T09:49:06Z
day: '07'
doi: 10.1016/0014-5793(91)81109-L
extern: '1'
external_id:
  pmid:
  - '1936255 '
intvolume: '       291'
issue: '1'
language:
- iso: eng
main_file_link:
- url: https://www.sciencedirect.com/science/article/pii/001457939181109L
month: '10'
oa_version: None
page: 84 - 86
pmid: 1
publication: FEBS Letters
publication_identifier:
  issn:
  - 0014-2956
publication_status: published
publisher: Elsevier
publist_id: '5139'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Respiratory burst inhibition in human neutrophils by ultra-low doses of [D-Ala2]
  methionine enkephalinamide
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 291
year: '1991'
...
---
_id: '4592'
article_processing_charge: No
article_type: letter_note
author:
- first_name: Rajeev
  full_name: Alur, Rajeev
  last_name: Alur
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000−0002−2985−7724
citation:
  ama: Alur R, Henzinger TA. Time for logic. <i>SIGACT News</i>. 1991;22(3):6-12.
  apa: Alur, R., &#38; Henzinger, T. A. (1991). Time for logic. <i>SIGACT News</i>.
    ACM.
  chicago: Alur, Rajeev, and Thomas A Henzinger. “Time for Logic.” <i>SIGACT News</i>.
    ACM, 1991.
  ieee: R. Alur and T. A. Henzinger, “Time for logic,” <i>SIGACT News</i>, vol. 22,
    no. 3. ACM, pp. 6–12, 1991.
  ista: Alur R, Henzinger TA. 1991. Time for logic. SIGACT News. 22(3), 6–12.
  mla: Alur, Rajeev, and Thomas A. Henzinger. “Time for Logic.” <i>SIGACT News</i>,
    vol. 22, no. 3, ACM, 1991, pp. 6–12.
  short: R. Alur, T.A. Henzinger, SIGACT News 22 (1991) 6–12.
date_created: 2018-12-11T12:09:39Z
date_published: 1991-01-01T00:00:00Z
date_updated: 2022-02-24T13:54:10Z
day: '01'
extern: '1'
intvolume: '        22'
issue: '3'
language:
- iso: eng
main_file_link:
- url: https://dl.acm.org/toc/sigact/1991/22/1
month: '01'
oa_version: None
page: 6 - 12
publication: SIGACT News
publication_identifier:
  issn:
  - 0163-5700
publication_status: published
publisher: ACM
publist_id: '113'
quality_controlled: '1'
status: public
title: Time for logic
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 22
year: '1991'
...
---
_id: '4621'
abstract:
- lang: eng
  text: The  most  natural,  compositional,  way  of  modeling  real-time  systems  uses  a  dense
    domain  for  time.  The  satisfiability  of  timing  constraints  that  are  capable  of  expressing  punctuality
    in  this  model,  however,  is  known  to  be  undecidable.  We  introduce  a  temporal  language  that  can
    constrain  the  time  difference  between  events  only  with  finite,  yet  arbitrary,  precision  and  show  the
    resulting  logic  to  be  EXPSPACE-complete.  This  result  allows  us  to  develop  an  algorithm  for  the
    verification  of  timing  properties  of  real-time  systems  with  a  dense  semantics.
acknowledgement: 'We  wish  to  thank  an  anonymous  referee  for  pointing  out
  the  PSPACE-fragment  of  Section  4.5.  T. A. Henzinger was supported in part by
  the Office of Naval Research Young Investigator award NOOO14-95-l-0520, by the National
  Science Foundation CAREER award CCR 9501708, by the National Science Foundation
  grants CCR 92-00794 and CCR 9504469, by the Air Force Office of Scientific Research
  contract F49620-93-l-0056, and by the Advanced Research Projects Agency grant NAG2-892. '
article_processing_charge: No
author:
- first_name: Rajeev
  full_name: Alur, Rajeev
  last_name: Alur
- first_name: Tomás
  full_name: Feder, Tomás
  last_name: Feder
- first_name: Thomas A
  full_name: Henzinger, Thomas A
  id: 40876CD8-F248-11E8-B48F-1D18A9856A87
  last_name: Henzinger
  orcid: 0000−0002−2985−7724
citation:
  ama: 'Alur R, Feder T, Henzinger TA. The benefits of relaxing punctuality. In: <i>Proceedings
    of the 10th Annual ACM Symposium on Principles of Distributed Computing</i>. ACM;
    1991:139-152. doi:<a href="https://doi.org/10.1145/227595.227602">10.1145/227595.227602</a>'
  apa: 'Alur, R., Feder, T., &#38; Henzinger, T. A. (1991). The benefits of relaxing
    punctuality. In <i>Proceedings of the 10th Annual ACM Symposium on Principles
    of Distributed Computing</i> (pp. 139–152). Montreal, Canada: ACM. <a href="https://doi.org/10.1145/227595.227602">https://doi.org/10.1145/227595.227602</a>'
  chicago: Alur, Rajeev, Tomás Feder, and Thomas A Henzinger. “The Benefits of Relaxing
    Punctuality.” In <i>Proceedings of the 10th Annual ACM Symposium on Principles
    of Distributed Computing</i>, 139–52. ACM, 1991. <a href="https://doi.org/10.1145/227595.227602">https://doi.org/10.1145/227595.227602</a>.
  ieee: R. Alur, T. Feder, and T. A. Henzinger, “The benefits of relaxing punctuality,”
    in <i>Proceedings of the 10th Annual ACM Symposium on Principles of Distributed
    Computing</i>, Montreal, Canada, 1991, pp. 139–152.
  ista: 'Alur R, Feder T, Henzinger TA. 1991. The benefits of relaxing punctuality.
    Proceedings of the 10th Annual ACM Symposium on Principles of Distributed Computing.
    PODC: Principles of Distributed Computing, 139–152.'
  mla: Alur, Rajeev, et al. “The Benefits of Relaxing Punctuality.” <i>Proceedings
    of the 10th Annual ACM Symposium on Principles of Distributed Computing</i>, ACM,
    1991, pp. 139–52, doi:<a href="https://doi.org/10.1145/227595.227602">10.1145/227595.227602</a>.
  short: R. Alur, T. Feder, T.A. Henzinger, in:, Proceedings of the 10th Annual ACM
    Symposium on Principles of Distributed Computing, ACM, 1991, pp. 139–152.
conference:
  end_date: 1991-08-21
  location: Montreal, Canada
  name: 'PODC: Principles of Distributed Computing'
  start_date: 1991-08-19
date_created: 2018-12-11T12:09:48Z
date_published: 1991-01-01T00:00:00Z
date_updated: 2022-02-24T13:27:20Z
day: '01'
doi: 10.1145/227595.227602
extern: '1'
language:
- iso: eng
main_file_link:
- url: https://dl.acm.org/doi/10.1145/227595.227602
month: '01'
oa_version: None
page: 139 - 152
publication: Proceedings of the 10th Annual ACM Symposium on Principles of Distributed
  Computing
publication_identifier:
  isbn:
  - 978-0-89791-439-0
publication_status: published
publisher: ACM
publist_id: '86'
quality_controlled: '1'
scopus_import: '1'
status: public
title: The benefits of relaxing punctuality
type: conference
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
year: '1991'
...
---
_id: '3468'
abstract:
- lang: eng
  text: "Two types of metabolically regulated K channels have been identified for
    the first time in enzymatically demyelinated fibres of amphibian sciatic nerve
    using the patch-clamp technique. A maxi K channel with a single-channel conductance
    of 132 pS (105 mM K on both sides of the membrane, 15°C) is activated both by
    micromolar concentrations of internal Ca and by depolarization. A second type
    of K channel with a conductance of 44 pS is inhibited by intracellular adenosine
    5'-triphosphate (ATP) with a half-maximal inhibitory concentration (IC50) of 35
    μM. It is blocked by submicromolar concentrations of external glibenclamide. Both
    channels are sensitive to external tetraethylammonium chloride (IC50 = 0.2 mM
    for the maxi K channel and 4.2 mM for the ATP-sensitive channel). They may be
    part of a complex feedback system regulating axonal excitability under various
    metabolic conditions.\r\n"
article_processing_charge: No
article_type: original
author:
- first_name: Peter M
  full_name: Jonas, Peter M
  id: 353C1B58-F248-11E8-B48F-1D18A9856A87
  last_name: Jonas
  orcid: 0000-0001-5001-4804
- first_name: Duk
  full_name: Koh, Duk
  last_name: Koh
- first_name: Knut
  full_name: Kampe, Knut
  last_name: Kampe
- first_name: Markus
  full_name: Hermsteiner, Markus
  last_name: Hermsteiner
- first_name: Werner
  full_name: Vogel, Werner
  last_name: Vogel
citation:
  ama: 'Jonas PM, Koh D, Kampe K, Hermsteiner M, Vogel W. ATP-sensitive and Ca-activated
    K channels in vertebrate axons: novel links between metabolism and excitability.
    <i>Pflügers Archiv : European Journal of Physiology</i>. 1991;418(1-2):68-73.
    doi:<a href="https://doi.org/10.1007/BF00370453">10.1007/BF00370453</a>'
  apa: 'Jonas, P. M., Koh, D., Kampe, K., Hermsteiner, M., &#38; Vogel, W. (1991).
    ATP-sensitive and Ca-activated K channels in vertebrate axons: novel links between
    metabolism and excitability. <i>Pflügers Archiv : European Journal of Physiology</i>.
    Springer. <a href="https://doi.org/10.1007/BF00370453">https://doi.org/10.1007/BF00370453</a>'
  chicago: 'Jonas, Peter M, Duk Koh, Knut Kampe, Markus Hermsteiner, and Werner Vogel.
    “ATP-Sensitive and Ca-Activated K Channels in Vertebrate Axons: Novel Links between
    Metabolism and Excitability.” <i>Pflügers Archiv : European Journal of Physiology</i>.
    Springer, 1991. <a href="https://doi.org/10.1007/BF00370453">https://doi.org/10.1007/BF00370453</a>.'
  ieee: 'P. M. Jonas, D. Koh, K. Kampe, M. Hermsteiner, and W. Vogel, “ATP-sensitive
    and Ca-activated K channels in vertebrate axons: novel links between metabolism
    and excitability,” <i>Pflügers Archiv : European Journal of Physiology</i>, vol.
    418, no. 1–2. Springer, pp. 68–73, 1991.'
  ista: 'Jonas PM, Koh D, Kampe K, Hermsteiner M, Vogel W. 1991. ATP-sensitive and
    Ca-activated K channels in vertebrate axons: novel links between metabolism and
    excitability. Pflügers Archiv : European Journal of Physiology. 418(1–2), 68–73.'
  mla: 'Jonas, Peter M., et al. “ATP-Sensitive and Ca-Activated K Channels in Vertebrate
    Axons: Novel Links between Metabolism and Excitability.” <i>Pflügers Archiv :
    European Journal of Physiology</i>, vol. 418, no. 1–2, Springer, 1991, pp. 68–73,
    doi:<a href="https://doi.org/10.1007/BF00370453">10.1007/BF00370453</a>.'
  short: 'P.M. Jonas, D. Koh, K. Kampe, M. Hermsteiner, W. Vogel, Pflügers Archiv :
    European Journal of Physiology 418 (1991) 68–73.'
date_created: 2018-12-11T12:03:29Z
date_published: 1991-01-01T00:00:00Z
date_updated: 2022-03-03T14:42:06Z
day: '01'
doi: 10.1007/BF00370453
extern: '1'
external_id:
  pmid:
  - '2041727'
intvolume: '       418'
issue: 1-2
language:
- iso: eng
main_file_link:
- url: https://link.springer.com/article/10.1007/BF00370453
month: '01'
oa_version: None
page: 68 - 73
pmid: 1
publication: 'Pflügers Archiv : European Journal of Physiology'
publication_identifier:
  eissn:
  - 1432-2013
  issn:
  - 0031-6768
publication_status: published
publisher: Springer
publist_id: '2919'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'ATP-sensitive and Ca-activated K channels in vertebrate axons: novel links
  between metabolism and excitability'
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 418
year: '1991'
...
---
_id: '3566'
abstract:
- lang: eng
  text: This paper proves an O(m2/3n2/3 + m + n) upper bound on the number of incidences
    between m points and n hyperplanes in four dimensions, assuming all points lie
    on one side of each hyperplane and the points and hyperplanes satisfy certain
    natural general position conditions. This result has application to various three-dimensional
    combinatorial distance problems. For example, it implies the same upper bound
    for the number of bichromatic minimum distance pairs in a set of m blue and n
    red points in three-dimensional space. This improves the best previous bound for
    this problem. © Springer-Verlag Berlin Heidelberg 1990.
alternative_title:
- DIMACS Series in Discrete Mathematics and Theoretical Computer Science
article_processing_charge: No
author:
- first_name: Herbert
  full_name: Edelsbrunner, Herbert
  id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
  last_name: Edelsbrunner
  orcid: 0000-0002-9823-6833
- first_name: Micha
  full_name: Sharir, Micha
  last_name: Sharir
citation:
  ama: 'Edelsbrunner H, Sharir M. A hyperplane incidence problem with applications
    to counting distances. In: <i>Applied Geometry and Discrete Mathematics: The Victor
    Klee Festschrift</i>. Vol 4. American Mathematical Society; 1991:253-263.'
  apa: 'Edelsbrunner, H., &#38; Sharir, M. (1991). A hyperplane incidence problem
    with applications to counting distances. In <i>Applied Geometry and Discrete Mathematics:
    The Victor Klee Festschrift</i> (Vol. 4, pp. 253–263). American Mathematical Society.'
  chicago: 'Edelsbrunner, Herbert, and Micha Sharir. “A Hyperplane Incidence Problem
    with Applications to Counting Distances.” In <i>Applied Geometry and Discrete
    Mathematics: The Victor Klee Festschrift</i>, 4:253–63. American Mathematical
    Society, 1991.'
  ieee: 'H. Edelsbrunner and M. Sharir, “A hyperplane incidence problem with applications
    to counting distances,” in <i>Applied Geometry and Discrete Mathematics: The Victor
    Klee Festschrift</i>, vol. 4, American Mathematical Society, 1991, pp. 253–263.'
  ista: 'Edelsbrunner H, Sharir M. 1991.A hyperplane incidence problem with applications
    to counting distances. In: Applied Geometry and Discrete Mathematics: The Victor
    Klee Festschrift. DIMACS Series in Discrete Mathematics and Theoretical Computer
    Science, vol. 4, 253–263.'
  mla: 'Edelsbrunner, Herbert, and Micha Sharir. “A Hyperplane Incidence Problem with
    Applications to Counting Distances.” <i>Applied Geometry and Discrete Mathematics:
    The Victor Klee Festschrift</i>, vol. 4, American Mathematical Society, 1991,
    pp. 253–63.'
  short: 'H. Edelsbrunner, M. Sharir, in:, Applied Geometry and Discrete Mathematics:
    The Victor Klee Festschrift, American Mathematical Society, 1991, pp. 253–263.'
date_created: 2018-12-11T12:04:00Z
date_published: 1991-04-01T00:00:00Z
date_updated: 2022-03-03T13:27:01Z
day: '01'
extern: '1'
intvolume: '         4'
language:
- iso: eng
main_file_link:
- url: http://www.cs.duke.edu/~edels/Papers/1991-B-01-HyperplaneIncidence.pdf
month: '04'
oa_version: None
page: 253 - 263
publication: 'Applied Geometry and Discrete Mathematics: The Victor Klee Festschrift'
publication_identifier:
  isbn:
  - 978-0897913850
publication_status: published
publisher: American Mathematical Society
publist_id: '2819'
quality_controlled: '1'
scopus_import: '1'
status: public
title: A hyperplane incidence problem with applications to counting distances
type: book_chapter
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 4
year: '1991'
...
---
_id: '3567'
abstract:
- lang: eng
  text: 'Many computational geometry problems arc exceedingly more difficult if the
    setting is the (three-dimensional real) space R3 rather than the plane . Most
    often the reason for this striking increase in complexity is the appearance of
    new geometric phenomena caused by one-dimensional objects in space. The intention
    of recent studies on problems for lines in space is to shed light on these new
    phenomena and their complexities. This paper reviews some of the most important
    results and shows how they are related to problems in dimensions 2 and 5. '
acknowledgement: National Science Foundation under grant CCR-8921421.
alternative_title:
- DIAMCS Series in Discrete Mathematics and Theoretical Computer Science
article_processing_charge: No
author:
- first_name: Herbert
  full_name: Edelsbrunner, Herbert
  id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
  last_name: Edelsbrunner
  orcid: 0000-0002-9823-6833
citation:
  ama: 'Edelsbrunner H. Lines in space – A collection of results. In: <i>Discrete
    &#38; Computational Geometry: Papers from the Dimacs Special Year</i>. Vol 6.
    Springer; 1991:77-93.'
  apa: 'Edelsbrunner, H. (1991). Lines in space – A collection of results. In <i>Discrete
    &#38; Computational Geometry: Papers from the Dimacs Special Year</i> (Vol. 6,
    pp. 77–93). Springer.'
  chicago: 'Edelsbrunner, Herbert. “Lines in Space – A Collection of Results.” In
    <i>Discrete &#38; Computational Geometry: Papers from the Dimacs Special Year</i>,
    6:77–93. Springer, 1991.'
  ieee: 'H. Edelsbrunner, “Lines in space – A collection of results,” in <i>Discrete
    &#38; Computational Geometry: Papers from the Dimacs Special Year</i>, vol. 6,
    Springer, 1991, pp. 77–93.'
  ista: 'Edelsbrunner H. 1991.Lines in space – A collection of results. In: Discrete
    &#38; Computational Geometry: Papers from the Dimacs Special Year. DIAMCS Series
    in Discrete Mathematics and Theoretical Computer Science, vol. 6, 77–93.'
  mla: 'Edelsbrunner, Herbert. “Lines in Space – A Collection of Results.” <i>Discrete
    &#38; Computational Geometry: Papers from the Dimacs Special Year</i>, vol. 6,
    Springer, 1991, pp. 77–93.'
  short: 'H. Edelsbrunner, in:, Discrete &#38; Computational Geometry: Papers from
    the Dimacs Special Year, Springer, 1991, pp. 77–93.'
date_created: 2018-12-11T12:04:00Z
date_published: 1991-06-01T00:00:00Z
date_updated: 2022-03-03T10:48:15Z
day: '01'
extern: '1'
intvolume: '         6'
language:
- iso: eng
main_file_link:
- url: https://pub.ist.ac.at/~edels/Papers/1991-B-02-LinesInSpaceACollection.pdf
month: '06'
oa_version: None
page: 77 - 93
publication: 'Discrete & Computational Geometry: Papers from the Dimacs Special Year'
publication_identifier:
  isbn:
  - '9780821865958'
publication_status: published
publisher: Springer
publist_id: '2818'
quality_controlled: '1'
status: public
title: Lines in space – A collection of results
type: book_chapter
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 6
year: '1991'
...
---
_id: '3646'
abstract:
- lang: eng
  text: "We compare the pattern of morphological and electrophoretic variation in
    the hybrid zone between Bombina bombina and B. variegata across two transects:
    one near Cracow and one 200 km away, near Przemysl in southeastern Poland. Morphological
    variation across the Przemysl transect had been surveyed more than 50 years ago;
    though we found a significant shift at one site, there is no evidence for gross
    movement over this period. Morphological and electrophoretic changes coincide,
    and the average shape of the clines is the same across both transects. At the
    center, most of the change in frequency of six diagnostic allozymes occurs within
    w = 6.05 km (2-unit support limits 5.56-6.54 km). These steep gradients are generated
    not by selection on the allozymes themselves, but by associations with other loci:
    though these markers are unlinked, they are in strong linkage disequilibrium with
    each other [R = D/ = 0.22 (0.15-0.29) at the center]. Disequilibria are broken
    up as alleles diffuse away from the zone and flow into the new genetic background.
    The net barrier to the flow of genes from bombina into variegata, which is generated
    by these disequilibria, is B = 51 (22-81) km. The fitness of hybrids must be substantially
    reduced to produce such a barrier [W̄H/W̄P = 0.58 (0.54-0.68)], and this selection
    must be spread over many loci [N = 55 (26-88)]. Alleles introgress significantly
    less far than would be expected from the age of the zone and the estimated dispersal
    rate [σ = 0.99 (0.82-1.14) km gen.-1/2]: this implies selection of se = 0.37 (0.15-0.58)%
    on the enzymes themselves. There is weak but significant linkage disequilibrium
    well away from the center of the zone; this, together with the presence of parental
    and F1 genotypes, suggests some long-range migration. However, such migration
    is not likely to cause significant introgression.\r\n"
acknowledgement: This work was supported by grants from  the Royal Society, the Nuffield
  Foundation,  the University of London Central Research Fund, and the Polish Academy
  of Sciences (project MR-II.6). We also thank Dr. Jan Rafinski for help in collecting
  toads.
article_processing_charge: No
article_type: original
author:
- first_name: Jacek
  full_name: Szymura, Jacek
  last_name: Szymura
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
citation:
  ama: 'Szymura J, Barton NH. The genetic structure of the hybrid zone between the
    fire-bellied toads Bombina bombina and B. variegata: comparisons between transects
    and between loci. <i>Evolution</i>. 1991;45(2):237-261. doi:<a href="https://doi.org/10.1111/j.1558-5646.1991.tb04400.x">10.1111/j.1558-5646.1991.tb04400.x</a>'
  apa: 'Szymura, J., &#38; Barton, N. H. (1991). The genetic structure of the hybrid
    zone between the fire-bellied toads Bombina bombina and B. variegata: comparisons
    between transects and between loci. <i>Evolution</i>. Wiley-Blackwell. <a href="https://doi.org/10.1111/j.1558-5646.1991.tb04400.x">https://doi.org/10.1111/j.1558-5646.1991.tb04400.x</a>'
  chicago: 'Szymura, Jacek, and Nicholas H Barton. “The Genetic Structure of the Hybrid
    Zone between the Fire-Bellied Toads Bombina Bombina and B. Variegata: Comparisons
    between Transects and between Loci.” <i>Evolution</i>. Wiley-Blackwell, 1991.
    <a href="https://doi.org/10.1111/j.1558-5646.1991.tb04400.x">https://doi.org/10.1111/j.1558-5646.1991.tb04400.x</a>.'
  ieee: 'J. Szymura and N. H. Barton, “The genetic structure of the hybrid zone between
    the fire-bellied toads Bombina bombina and B. variegata: comparisons between transects
    and between loci,” <i>Evolution</i>, vol. 45, no. 2. Wiley-Blackwell, pp. 237–261,
    1991.'
  ista: 'Szymura J, Barton NH. 1991. The genetic structure of the hybrid zone between
    the fire-bellied toads Bombina bombina and B. variegata: comparisons between transects
    and between loci. Evolution. 45(2), 237–261.'
  mla: 'Szymura, Jacek, and Nicholas H. Barton. “The Genetic Structure of the Hybrid
    Zone between the Fire-Bellied Toads Bombina Bombina and B. Variegata: Comparisons
    between Transects and between Loci.” <i>Evolution</i>, vol. 45, no. 2, Wiley-Blackwell,
    1991, pp. 237–61, doi:<a href="https://doi.org/10.1111/j.1558-5646.1991.tb04400.x">10.1111/j.1558-5646.1991.tb04400.x</a>.'
  short: J. Szymura, N.H. Barton, Evolution 45 (1991) 237–261.
date_created: 2018-12-11T12:04:25Z
date_published: 1991-03-01T00:00:00Z
date_updated: 2022-03-02T15:50:09Z
day: '01'
doi: 10.1111/j.1558-5646.1991.tb04400.x
extern: '1'
external_id:
  pmid:
  - '28567861 '
intvolume: '        45'
issue: '2'
language:
- iso: eng
main_file_link:
- url: ' http://www.jstor.org/stable/2409660'
month: '03'
oa_version: None
page: 237 - 261
pmid: 1
publication: Evolution
publication_identifier:
  eissn:
  - 1558-5646
  issn:
  - 0014-3820
publication_status: published
publisher: Wiley-Blackwell
publist_id: '2737'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'The genetic structure of the hybrid zone between the fire-bellied toads Bombina
  bombina and B. variegata: comparisons between transects and between loci'
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 45
year: '1991'
...
