---
_id: '2484'
abstract:
- lang: eng
text: Three cDNA clones, mGluR2, mGluR3, and mGluR4, were isolated from a rat brain
cDNA library by cross-hybridization with the cDNA for a metabotropic glutamate
receptor (mGluR1). The cloned receptors show considerable sequence similarity
with mGluR1 and possess a large extracellular domain preceding the seven putative
membrane-spanning segments. mGluR2 is expressed in some particular neuronal cells
different from those expressing mGluR1 and mediates an efficient inhibition of
forskolin-stimulated cAMP formation in cDNA- transfected cells. The mGluRs thus
form a novel family of G protein-coupled receptors that differ in their signal
transduction and expression patterns.
acknowledgement: 'We are grateful to Noboru Mizuno for helpful discussion and Akira
Uesugi for photographic assistance. This work was sup. ported in part by research
grants from the Ministry of Education, Science and Culture of Japan. The costs of
publication of this article were defrayed in part by the payment of page charges.
This article must therefore be hereby marked "advertisement" in accordance with
18 USC Sec-tion 1734 solely to indicate this fact. '
article_processing_charge: No
article_type: original
author:
- first_name: Yasuto
full_name: Tanabe, Yasuto
last_name: Tanabe
- first_name: Masayuki
full_name: Masu, Masayuki
last_name: Masu
- first_name: Takahiro
full_name: Ishii, Takahiro
last_name: Ishii
- first_name: Ryuichi
full_name: Shigemoto, Ryuichi
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Shigetada
full_name: Nakanishi, Shigetada
last_name: Nakanishi
citation:
ama: Tanabe Y, Masu M, Ishii T, Shigemoto R, Nakanishi S. A family of metabotropic
glutamate receptors. Neuron. 1992;8(1):169-179. doi:10.1016/0896-6273(92)90118-W
apa: Tanabe, Y., Masu, M., Ishii, T., Shigemoto, R., & Nakanishi, S. (1992).
A family of metabotropic glutamate receptors. Neuron. Elsevier. https://doi.org/10.1016/0896-6273(92)90118-W
chicago: Tanabe, Yasuto, Masayuki Masu, Takahiro Ishii, Ryuichi Shigemoto, and Shigetada
Nakanishi. “A Family of Metabotropic Glutamate Receptors.” Neuron. Elsevier,
1992. https://doi.org/10.1016/0896-6273(92)90118-W.
ieee: Y. Tanabe, M. Masu, T. Ishii, R. Shigemoto, and S. Nakanishi, “A family of
metabotropic glutamate receptors,” Neuron, vol. 8, no. 1. Elsevier, pp.
169–179, 1992.
ista: Tanabe Y, Masu M, Ishii T, Shigemoto R, Nakanishi S. 1992. A family of metabotropic
glutamate receptors. Neuron. 8(1), 169–179.
mla: Tanabe, Yasuto, et al. “A Family of Metabotropic Glutamate Receptors.” Neuron,
vol. 8, no. 1, Elsevier, 1992, pp. 169–79, doi:10.1016/0896-6273(92)90118-W.
short: Y. Tanabe, M. Masu, T. Ishii, R. Shigemoto, S. Nakanishi, Neuron 8 (1992)
169–179.
date_created: 2018-12-11T11:57:56Z
date_published: 1992-01-01T00:00:00Z
date_updated: 2022-03-21T10:17:07Z
day: '01'
doi: 10.1016/0896-6273(92)90118-W
extern: '1'
external_id:
pmid:
- '1309649 '
intvolume: ' 8'
issue: '1'
language:
- iso: eng
main_file_link:
- url: https://www.sciencedirect.com/science/article/pii/089662739290118W?via%3Dihub
month: '01'
oa_version: None
page: 169 - 179
pmid: 1
publication: Neuron
publication_identifier:
issn:
- 0896-6273
publication_status: published
publisher: Elsevier
publist_id: '4417'
quality_controlled: '1'
scopus_import: '1'
status: public
title: A family of metabotropic glutamate receptors
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 8
year: '1992'
...
---
_id: '2485'
abstract:
- lang: eng
text: Endothelins (ETs) are very potent vasoconstrictive peptides and have diverse
functions in both vascular and nonvascular tissues. This investigation concerns
the tissue distribution and cellular localization of rat mRNAs encoding two different
subtypes of ET receptors (ET(A) and ET(B)). We isolated 46 cDNA clones from a
rat lung cDNA library by hybridization with the bovine ET(A) cDNA. The characterization
of these cDNA clones indicated that they represent either the ET(A) or ET(B) cDNA.
In situ and blot hybridization analyses revealed that the rat ET(A) mRNA is predominantly
expressed in vascular smooth muscle cells of a variety of tissues, bronchial smooth
muscle cells, myocardium, and the pituitary gland. There is no significant expression
of ET(B) mRNA in vascular smooth muscle cells, and ET(A), thus, plays a primary
role in ET-induced vascular contraction. ET(B) mRNA is more widely distributed
in various cell types of many tissues. Its prominent expression is seen in glial
cells throughout the brain regions, epithelial cells of the choroid plexus, ependymal
cells lining the ventricle, myocardium, endothelial cells of glomeruli, and epithelial
cells of the thin segments of Henle's loops. Our investigation demonstrates that
the mRNAs for the two subtypes of rat ET receptors show specialized expression
patterns of cell types in both brain and peripheral tissues.
article_processing_charge: No
article_type: original
author:
- first_name: Seiji
full_name: Hori, Seiji
last_name: Hori
- first_name: Yasato
full_name: Komatsu, Yasato
last_name: Komatsu
- first_name: Ryuichi
full_name: Shigemoto, Ryuichi
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Noboru
full_name: Mizuno, Noboru
last_name: Mizuno
- first_name: Shigetada
full_name: Nakanishi, Shigetada
last_name: Nakanishi
citation:
ama: Hori S, Komatsu Y, Shigemoto R, Mizuno N, Nakanishi S. Distinct tissue distribution
and cellular localization of two messenger ribonucleic acids encoding different
subtypes of rat endothelin receptors. Endocrinology. 1992;130(4):1885-1895.
doi:10.1210/endo.130.4.1312429
apa: Hori, S., Komatsu, Y., Shigemoto, R., Mizuno, N., & Nakanishi, S. (1992).
Distinct tissue distribution and cellular localization of two messenger ribonucleic
acids encoding different subtypes of rat endothelin receptors. Endocrinology.
The Endocrine Society. https://doi.org/10.1210/endo.130.4.1312429
chicago: Hori, Seiji, Yasato Komatsu, Ryuichi Shigemoto, Noboru Mizuno, and Shigetada
Nakanishi. “Distinct Tissue Distribution and Cellular Localization of Two Messenger
Ribonucleic Acids Encoding Different Subtypes of Rat Endothelin Receptors.” Endocrinology.
The Endocrine Society, 1992. https://doi.org/10.1210/endo.130.4.1312429.
ieee: S. Hori, Y. Komatsu, R. Shigemoto, N. Mizuno, and S. Nakanishi, “Distinct
tissue distribution and cellular localization of two messenger ribonucleic acids
encoding different subtypes of rat endothelin receptors,” Endocrinology,
vol. 130, no. 4. The Endocrine Society, pp. 1885–1895, 1992.
ista: Hori S, Komatsu Y, Shigemoto R, Mizuno N, Nakanishi S. 1992. Distinct tissue
distribution and cellular localization of two messenger ribonucleic acids encoding
different subtypes of rat endothelin receptors. Endocrinology. 130(4), 1885–1895.
mla: Hori, Seiji, et al. “Distinct Tissue Distribution and Cellular Localization
of Two Messenger Ribonucleic Acids Encoding Different Subtypes of Rat Endothelin
Receptors.” Endocrinology, vol. 130, no. 4, The Endocrine Society, 1992,
pp. 1885–95, doi:10.1210/endo.130.4.1312429.
short: S. Hori, Y. Komatsu, R. Shigemoto, N. Mizuno, S. Nakanishi, Endocrinology
130 (1992) 1885–1895.
date_created: 2018-12-11T11:57:56Z
date_published: 1992-04-01T00:00:00Z
date_updated: 2022-03-21T09:54:59Z
day: '01'
doi: 10.1210/endo.130.4.1312429
extern: '1'
external_id:
pmid:
- '1312429'
intvolume: ' 130'
issue: '4'
language:
- iso: eng
main_file_link:
- url: https://academic.oup.com/endo/article-abstract/130/4/1885/2535978
month: '04'
oa_version: None
page: 1885 - 1895
pmid: 1
publication: Endocrinology
publication_identifier:
issn:
- 0013-7227
publication_status: published
publisher: The Endocrine Society
publist_id: '4416'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Distinct tissue distribution and cellular localization of two messenger ribonucleic
acids encoding different subtypes of rat endothelin receptors
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 130
year: '1992'
...
---
_id: '2486'
abstract:
- lang: eng
text: Distribution of the mRNA for a metabotropic glutamate receptor (mGluR1), which
is linked to phosphoinositide (PI) hydrolysis, was investigated in adult and developing
rat central nervous system (CNS) by in situ hybridization. Transcripts of mGluR1
were specifically localized to neurons and widely distributed throughout the adult
rat brain. Most intensely labeled neurons were Purkinje cells of the cerebellum,
mitral and tufted cells of the olfactory bulb, and neurons in the hippocampus,
lateral septum, thalamus, globus pallidus, entopeduncular nucleus, ventral pallidum,
magnocellular preoptic nucleus, substantia nigra, and dorsal cochlear nucleus.
Moderately labeled neurons were seen in high density in the dentate gyrus, striatum,
islands of Calleja, superficial layers of the retrosplenial, cingulate and entorhinal
cortices, mammillary nuclei, red nucleus, and superior colliculus. In the developing
rat brain, the level of mGluR1 expression gradually increased during early postnatal
days in accordance with the maturation of neuronal elements. These results show
prominent expression of mGluR1 in the major targets of putative glutamatergic
pathways and unique distribution pattern of mGluR1 distinct from those reported
for ionotropic subtypes of glutamate receptors, suggesting specific roles of mGluR1
in the glutamatergic system.
acknowledgement: We are grateful to Mr. Akira Uesugi for photographic help. This
work was supported in part by research grants from Senri Life Science Foundation
and the Ministry of Education, Science and Culture of Japan.
article_processing_charge: No
article_type: original
author:
- first_name: Ryuichi
full_name: Shigemoto, Ryuichi
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Shigetada
full_name: Nakanishi, Shigetada
last_name: Nakanishi
- first_name: Noboru
full_name: Mizuno, Noboru
last_name: Mizuno
citation:
ama: 'Shigemoto R, Nakanishi S, Mizuno N. Distribution of the mRNA for a metabotropic
glutamate receptor (mGluR1) in the central nervous system: An in situ hybridization
study in adult and developing rat. Journal of Comparative Neurology. 1992;322(1):121-135.
doi:10.1002/cne.903220110'
apa: 'Shigemoto, R., Nakanishi, S., & Mizuno, N. (1992). Distribution of the
mRNA for a metabotropic glutamate receptor (mGluR1) in the central nervous system:
An in situ hybridization study in adult and developing rat. Journal of Comparative
Neurology. Wiley-Blackwell. https://doi.org/10.1002/cne.903220110'
chicago: 'Shigemoto, Ryuichi, Shigetada Nakanishi, and Noboru Mizuno. “Distribution
of the MRNA for a Metabotropic Glutamate Receptor (MGluR1) in the Central Nervous
System: An in Situ Hybridization Study in Adult and Developing Rat.” Journal
of Comparative Neurology. Wiley-Blackwell, 1992. https://doi.org/10.1002/cne.903220110.'
ieee: 'R. Shigemoto, S. Nakanishi, and N. Mizuno, “Distribution of the mRNA for
a metabotropic glutamate receptor (mGluR1) in the central nervous system: An in
situ hybridization study in adult and developing rat,” Journal of Comparative
Neurology, vol. 322, no. 1. Wiley-Blackwell, pp. 121–135, 1992.'
ista: 'Shigemoto R, Nakanishi S, Mizuno N. 1992. Distribution of the mRNA for a
metabotropic glutamate receptor (mGluR1) in the central nervous system: An in
situ hybridization study in adult and developing rat. Journal of Comparative Neurology.
322(1), 121–135.'
mla: 'Shigemoto, Ryuichi, et al. “Distribution of the MRNA for a Metabotropic Glutamate
Receptor (MGluR1) in the Central Nervous System: An in Situ Hybridization Study
in Adult and Developing Rat.” Journal of Comparative Neurology, vol. 322,
no. 1, Wiley-Blackwell, 1992, pp. 121–35, doi:10.1002/cne.903220110.'
short: R. Shigemoto, S. Nakanishi, N. Mizuno, Journal of Comparative Neurology 322
(1992) 121–135.
date_created: 2018-12-11T11:57:57Z
date_published: 1992-08-01T00:00:00Z
date_updated: 2022-03-21T09:41:37Z
day: '01'
doi: 10.1002/cne.903220110
extern: '1'
external_id:
pmid:
- '1430307'
intvolume: ' 322'
issue: '1'
language:
- iso: eng
main_file_link:
- url: https://onlinelibrary.wiley.com/doi/10.1002/cne.903220110
month: '08'
oa_version: Published Version
page: 121 - 135
pmid: 1
publication: Journal of Comparative Neurology
publication_identifier:
issn:
- 0021-9967
publication_status: published
publisher: Wiley-Blackwell
publist_id: '4415'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Distribution of the mRNA for a metabotropic glutamate receptor (mGluR1) in
the central nervous system: An in situ hybridization study in adult and developing
rat'
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 322
year: '1992'
...
---
_id: '2531'
abstract:
- lang: eng
text: The distribution of NMDA receptor (NMDAR1) on neurons in the peripheral ganglia
was examined in the adult rat by in situ hybridization. NMDAR1 mRNA was expressed
in all neurons in the sensory and autonomic ganglia examined; in the dorsal root,
trigeminal, nodose, superior cervical, and sphenopalatine ganglia. Possible roles
of the NMDA receptor on the sensory and autonomic ganglion neurons are discussed.
acknowledgement: The photographic help of Mr. Akira Uesugi is gratefully acknowledged.
This work has been supported by research grants from the Ministry of Education,
Science and Culture of Japan.
article_processing_charge: No
article_type: original
author:
- first_name: Ryuichi
full_name: Shigemoto, Ryuichi
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Hitoshi
full_name: Ohishi, Hitoshi
last_name: Ohishi
- first_name: Shigetada
full_name: Nakanishi, Shigetada
last_name: Nakanishi
- first_name: Noboru
full_name: Mizuno, Noboru
last_name: Mizuno
citation:
ama: Shigemoto R, Ohishi H, Nakanishi S, Mizuno N. Expression of the mRNA for the
rat NMDA receptor (NMDAR1) in the sensory and autonomic ganglion neurons. Neuroscience
Letters. 1992;144(1-2):229-232. doi:10.1016/0304-3940(92)90756-W
apa: Shigemoto, R., Ohishi, H., Nakanishi, S., & Mizuno, N. (1992). Expression
of the mRNA for the rat NMDA receptor (NMDAR1) in the sensory and autonomic ganglion
neurons. Neuroscience Letters. Elsevier. https://doi.org/10.1016/0304-3940(92)90756-W
chicago: Shigemoto, Ryuichi, Hitoshi Ohishi, Shigetada Nakanishi, and Noboru Mizuno.
“Expression of the MRNA for the Rat NMDA Receptor (NMDAR1) in the Sensory and
Autonomic Ganglion Neurons.” Neuroscience Letters. Elsevier, 1992. https://doi.org/10.1016/0304-3940(92)90756-W.
ieee: R. Shigemoto, H. Ohishi, S. Nakanishi, and N. Mizuno, “Expression of the mRNA
for the rat NMDA receptor (NMDAR1) in the sensory and autonomic ganglion neurons,”
Neuroscience Letters, vol. 144, no. 1–2. Elsevier, pp. 229–232, 1992.
ista: Shigemoto R, Ohishi H, Nakanishi S, Mizuno N. 1992. Expression of the mRNA
for the rat NMDA receptor (NMDAR1) in the sensory and autonomic ganglion neurons.
Neuroscience Letters. 144(1–2), 229–232.
mla: Shigemoto, Ryuichi, et al. “Expression of the MRNA for the Rat NMDA Receptor
(NMDAR1) in the Sensory and Autonomic Ganglion Neurons.” Neuroscience Letters,
vol. 144, no. 1–2, Elsevier, 1992, pp. 229–32, doi:10.1016/0304-3940(92)90756-W.
short: R. Shigemoto, H. Ohishi, S. Nakanishi, N. Mizuno, Neuroscience Letters 144
(1992) 229–232.
date_created: 2018-12-11T11:58:13Z
date_published: 1992-09-14T00:00:00Z
date_updated: 2022-03-18T13:15:02Z
day: '14'
doi: 10.1016/0304-3940(92)90756-W
extern: '1'
external_id:
pmid:
- '1436707'
intvolume: ' 144'
issue: 1-2
language:
- iso: eng
main_file_link:
- url: https://www.sciencedirect.com/science/article/pii/030439409290756W
month: '09'
oa_version: None
page: 229 - 232
pmid: 1
publication: Neuroscience Letters
publication_identifier:
issn:
- 0304-3940
publication_status: published
publisher: Elsevier
publist_id: '4368'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Expression of the mRNA for the rat NMDA receptor (NMDAR1) in the sensory and
autonomic ganglion neurons
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 144
year: '1992'
...
---
_id: '2532'
abstract:
- lang: eng
text: In the present study, we have investigated the expression of both the erythrocyte-type
(GLUT1) and the brain-type (GLUT3) glucose transporter isoforms in primary human
brain tumors. In situ hybridization made it possible to localize and semiquantify
both GLUT1 and GLUT3 mRNAs of individual cells in all 18 samples examined. More
signals for GLUT3 mRNA than for GLUT1 mRNA were found over astrocytoma cells,
while the reverse was the case in all 6 meningiomas. In astrocytomas, for both
mRNAs, the density of silver grains over tumor cells was well correlated with
the malignancy of the cells. This correlation was, as was also confirmed by Northern
blot analysis, more marked with GLUT3 mRNA than with GLUT1 mRNA. In 2 of 5 anaplastic
astrocytomas and in all 3 glioblastomas, numerous tumor cells with large amounts
of both mRNAs tended to surround the perivascular regions. 'Tumor vessels' with
endothelial proliferation, an almost pathognomonic feature of glioblastomas, expressed
much GLUT3 mRNA but no significant GLUT1 mRNA, while a single- or a few-layered
capillary endothelium expressed much GLUT1 mRNA. The distribution of both mRNAs
was in good accordance with that of both proteins. Our results suggest that the
expression of both glucose transporter isoforms may contribute to the maintenance
of human brain tumors and that the expression of the GLUT3 isoform may be closely
related to the malignant change of astrocytomas and particularly related to the
aberrant neovascularization which accompanies glioblastomas.
acknowledgement: 'We wish to acknowledge generous donations of human samples by the
following neurosurgeons: Drs. Taro Fukumitsu. Akinori Kondo, Toyoshiro Yamamoto,
Juji Takeuchi, Junya Hanakita, Syunichi Yoneda, and Michio Nishikawa. We are very
grateful to Dr. G. I. Bell (The University of Chicago) for providing the cDNA clones
of GLUTI and GLUT3. We thank Drs. Yoshifumi Yokota, Yuichiro Yamada. and Manabu
Fukumoto for their helpful advice. We also thank Yoshinobu Toda and Hiroko Sato
for their expert technical assistance. Supported in part by Grants in Aids for Basic
Research on Radiation Therapy (03151034) and Special Project Research on Cancer
Bio-Science from the Ministry of Education, Science, and Culture of Japan, by Takeda
Medical Foundation, and by Monbusho International Scientific Research: Joint Research.'
article_processing_charge: No
article_type: original
author:
- first_name: Tatsuya
full_name: Nishioka, Tatsuya
last_name: Nishioka
- first_name: Yoshifumi
full_name: Oda, Yoshifumi
last_name: Oda
- first_name: Yutaka
full_name: Seino, Yutaka
last_name: Seino
- first_name: Taizo
full_name: Yamamoto, Taizo
last_name: Yamamoto
- first_name: Nobuya
full_name: Inagaki, Nobuya
last_name: Inagaki
- first_name: Hideki
full_name: Yano, Hideki
last_name: Yano
- first_name: Hiroo
full_name: Imura, Hiroo
last_name: Imura
- first_name: Ryuichi
full_name: Shigemoto, Ryuichi
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Haruhiko
full_name: Kikuchi, Haruhiko
last_name: Kikuchi
citation:
ama: Nishioka T, Oda Y, Seino Y, et al. Distribution of the glucose transporters
in human brain tumors. Cancer Research. 1992;52(14):3972-3979.
apa: Nishioka, T., Oda, Y., Seino, Y., Yamamoto, T., Inagaki, N., Yano, H., … Kikuchi,
H. (1992). Distribution of the glucose transporters in human brain tumors. Cancer
Research. American Association for Cancer Research.
chicago: Nishioka, Tatsuya, Yoshifumi Oda, Yutaka Seino, Taizo Yamamoto, Nobuya
Inagaki, Hideki Yano, Hiroo Imura, Ryuichi Shigemoto, and Haruhiko Kikuchi. “Distribution
of the Glucose Transporters in Human Brain Tumors.” Cancer Research. American
Association for Cancer Research, 1992.
ieee: T. Nishioka et al., “Distribution of the glucose transporters in human
brain tumors,” Cancer Research, vol. 52, no. 14. American Association for
Cancer Research, pp. 3972–3979, 1992.
ista: Nishioka T, Oda Y, Seino Y, Yamamoto T, Inagaki N, Yano H, Imura H, Shigemoto
R, Kikuchi H. 1992. Distribution of the glucose transporters in human brain tumors.
Cancer Research. 52(14), 3972–3979.
mla: Nishioka, Tatsuya, et al. “Distribution of the Glucose Transporters in Human
Brain Tumors.” Cancer Research, vol. 52, no. 14, American Association for
Cancer Research, 1992, pp. 3972–79.
short: T. Nishioka, Y. Oda, Y. Seino, T. Yamamoto, N. Inagaki, H. Yano, H. Imura,
R. Shigemoto, H. Kikuchi, Cancer Research 52 (1992) 3972–3979.
date_created: 2018-12-11T11:58:13Z
date_published: 1992-01-01T00:00:00Z
date_updated: 2022-03-17T15:38:42Z
day: '01'
extern: '1'
external_id:
pmid:
- '1617673'
intvolume: ' 52'
issue: '14'
language:
- iso: eng
main_file_link:
- url: https://aacrjournals.org/cancerres/article/52/14/3972/497930/Distribution-of-the-Glucose-Transporters-in-Human
month: '01'
oa_version: None
page: 3972 - 3979
pmid: 1
publication: Cancer Research
publication_identifier:
issn:
- 0008-5472
publication_status: published
publisher: American Association for Cancer Research
publist_id: '4367'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Distribution of the glucose transporters in human brain tumors
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 52
year: '1992'
...
---
_id: '2533'
abstract:
- lang: eng
text: A cDNA clone for a new metabotropic glutamate receptor, mGluR5, was isolated
through polymerase chain reaction-mediated DNA amplification by using primer sequences
conserved among the metabotropic glutamate receptor (mGluR) family and by the
subsequent screening of a rat brain cDNA library. The cloned receptor consists
of 1171 amino acid residues and exhibits a structural architecture common to the
mGluR family, possessing a large extracellular domain preceding the seven putative
membrane-spanning segments. mGluR5 shows the highest sequence similarity to mGluR1
among the mGluR members and is coupled to the stimulation of phosphatidylinositol
hydrolysis/ Ca2+ signal transduction in Chinese hamster ovary cells transfected
with the cloned cDNA. This receptor also resembles mGluR1 in its agonist selectivity
and antagonist responses; the potency rank order of agonists for mGluR5 was determined
to be quisqualate > L-glutamate ≥ ibotenate > trans-1-aminocyclopentane-1,3-dicarboxylate.
Blot and in situ hybridization analyses indicated that mGluR5 mRNA is widely distributed
in neuronal cells of the central nervous system and is expressed differently from
mGluR1 mRNA in many brain regions. This investigation thus demonstrates that there
is an additional mGluR subtype which closely resembles mGluR1 in its signal transduction
and pharmacological properties and is expressed in specialized neuronal cells
in the central nervous system.
acknowledgement: We are grateful to Seiji Ito for help of Ca2+ measurements and Akira
Uesugi for photographic assistance.
article_processing_charge: No
article_type: original
author:
- first_name: Takaaki
full_name: Abe, Takaaki
last_name: Abe
- first_name: Hidemitsu
full_name: Sugihara, Hidemitsu
last_name: Sugihara
- first_name: Hiroyuki
full_name: Nawa, Hiroyuki
last_name: Nawa
- first_name: Ryuichi
full_name: Shigemoto, Ryuichi
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Noboru
full_name: Mizuno, Noboru
last_name: Mizuno
- first_name: Shigetada
full_name: Nakanishi, Shigetada
last_name: Nakanishi
citation:
ama: Abe T, Sugihara H, Nawa H, Shigemoto R, Mizuno N, Nakanishi S. Molecular characterization
of a novel metabotropic glutamate receptor mGluR5 coupled to inositol phosphate/Ca2+
signal transduction. Journal of Biological Chemistry. 1992;267(19):13361-13368.
doi:10.1016/S0021-9258(18)42219-3
apa: Abe, T., Sugihara, H., Nawa, H., Shigemoto, R., Mizuno, N., & Nakanishi,
S. (1992). Molecular characterization of a novel metabotropic glutamate receptor
mGluR5 coupled to inositol phosphate/Ca2+ signal transduction. Journal of Biological
Chemistry. American Society for Biochemistry and Molecular Biology. https://doi.org/10.1016/S0021-9258(18)42219-3
chicago: Abe, Takaaki, Hidemitsu Sugihara, Hiroyuki Nawa, Ryuichi Shigemoto, Noboru
Mizuno, and Shigetada Nakanishi. “Molecular Characterization of a Novel Metabotropic
Glutamate Receptor MGluR5 Coupled to Inositol Phosphate/Ca2+ Signal Transduction.”
Journal of Biological Chemistry. American Society for Biochemistry and
Molecular Biology, 1992. https://doi.org/10.1016/S0021-9258(18)42219-3.
ieee: T. Abe, H. Sugihara, H. Nawa, R. Shigemoto, N. Mizuno, and S. Nakanishi, “Molecular
characterization of a novel metabotropic glutamate receptor mGluR5 coupled to
inositol phosphate/Ca2+ signal transduction,” Journal of Biological Chemistry,
vol. 267, no. 19. American Society for Biochemistry and Molecular Biology, pp.
13361–13368, 1992.
ista: Abe T, Sugihara H, Nawa H, Shigemoto R, Mizuno N, Nakanishi S. 1992. Molecular
characterization of a novel metabotropic glutamate receptor mGluR5 coupled to
inositol phosphate/Ca2+ signal transduction. Journal of Biological Chemistry.
267(19), 13361–13368.
mla: Abe, Takaaki, et al. “Molecular Characterization of a Novel Metabotropic Glutamate
Receptor MGluR5 Coupled to Inositol Phosphate/Ca2+ Signal Transduction.” Journal
of Biological Chemistry, vol. 267, no. 19, American Society for Biochemistry
and Molecular Biology, 1992, pp. 13361–68, doi:10.1016/S0021-9258(18)42219-3.
short: T. Abe, H. Sugihara, H. Nawa, R. Shigemoto, N. Mizuno, S. Nakanishi, Journal
of Biological Chemistry 267 (1992) 13361–13368.
date_created: 2018-12-11T11:58:14Z
date_published: 1992-07-05T00:00:00Z
date_updated: 2022-03-17T15:08:29Z
day: '05'
doi: 10.1016/S0021-9258(18)42219-3
extern: '1'
external_id:
pmid:
- '1320017'
intvolume: ' 267'
issue: '19'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.sciencedirect.com/science/article/pii/S0021925818422193
month: '07'
oa: 1
oa_version: Published Version
page: 13361 - 13368
pmid: 1
publication: Journal of Biological Chemistry
publication_identifier:
issn:
- 0021-9258
publication_status: published
publisher: American Society for Biochemistry and Molecular Biology
publist_id: '4366'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Molecular characterization of a novel metabotropic glutamate receptor mGluR5
coupled to inositol phosphate/Ca2+ signal transduction
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 267
year: '1992'
...
---
_id: '2534'
abstract:
- lang: eng
text: Vasoactive intestinal polypeptide (VIP), a 28 amino acid peptide hormone,
plays many physiological roles in the peripheral and central nerve systems. A
functional cDNA clone of the VIP receptor was isolated from a rat lung cDNA library
by cross-hybridization with the secretin receptor cDNA. VIP bound the cloned VIP
receptor expressed in mouse COP cells and stimulated adenylate cyclase through
the cloned receptor. The rat VIP receptor consists of 459 amino acids with a calculated
Mr of 52,054 and contains seven transmembrane segments. It is structurally related
to the secretin, calcitonin, and parathyroid hormone receptors, suggesting that
they constitute a new subfamily of the G5 protein - coupled receptors. VIP receptor
mRNA was detected in various rat tissues including liver, lung, intestines, and
brain. In situ hybridization revealed that VIP receptor mRNA is widely distributed
in neuronal cells of the adult rat brain, with a relatively high expression in
the cerebral cortex and hippocampus.
acknowledgement: "We thank Drs. R. Yoshida, K. Katoh, and K. lmamura for help with
the in situ hybridization, Dr. M. Nishizawa for discussion, and Ms. M. lkeda for
secretarial assistance. This work was supported in part by a Grant-in-Aid from the
Ministry of Education, Science and Culture of Japan. The costs of publication of
this article were defrayed in part\r\nby the payment of page charges. This article
must therefore be hereby marked “advertisement” in accordance with 18 USC Section
1734 solely to indicate this fact."
article_processing_charge: No
article_type: original
author:
- first_name: Takeshi
full_name: Ishihara, Takeshi
last_name: Ishihara
- first_name: Ryuichi
full_name: Shigemoto, Ryuichi
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Kensaku
full_name: Mori, Kensaku
last_name: Mori
- first_name: Kenji
full_name: Takahashi, Kenji
last_name: Takahashi
- first_name: Shigekazu
full_name: Nagata, Shigekazu
last_name: Nagata
citation:
ama: Ishihara T, Shigemoto R, Mori K, Takahashi K, Nagata S. Functional expression
and tissue distribution of a novel receptor for vasoactive intestinal polypeptide.
Neuron. 1992;8(4):811-819. doi:10.1016/0896-6273(92)90101-I
apa: Ishihara, T., Shigemoto, R., Mori, K., Takahashi, K., & Nagata, S. (1992).
Functional expression and tissue distribution of a novel receptor for vasoactive
intestinal polypeptide. Neuron. Elsevier. https://doi.org/10.1016/0896-6273(92)90101-I
chicago: Ishihara, Takeshi, Ryuichi Shigemoto, Kensaku Mori, Kenji Takahashi, and
Shigekazu Nagata. “Functional Expression and Tissue Distribution of a Novel Receptor
for Vasoactive Intestinal Polypeptide.” Neuron. Elsevier, 1992. https://doi.org/10.1016/0896-6273(92)90101-I.
ieee: T. Ishihara, R. Shigemoto, K. Mori, K. Takahashi, and S. Nagata, “Functional
expression and tissue distribution of a novel receptor for vasoactive intestinal
polypeptide,” Neuron, vol. 8, no. 4. Elsevier, pp. 811–819, 1992.
ista: Ishihara T, Shigemoto R, Mori K, Takahashi K, Nagata S. 1992. Functional expression
and tissue distribution of a novel receptor for vasoactive intestinal polypeptide.
Neuron. 8(4), 811–819.
mla: Ishihara, Takeshi, et al. “Functional Expression and Tissue Distribution of
a Novel Receptor for Vasoactive Intestinal Polypeptide.” Neuron, vol. 8,
no. 4, Elsevier, 1992, pp. 811–19, doi:10.1016/0896-6273(92)90101-I.
short: T. Ishihara, R. Shigemoto, K. Mori, K. Takahashi, S. Nagata, Neuron 8 (1992)
811–819.
date_created: 2018-12-11T11:58:14Z
date_published: 1992-04-01T00:00:00Z
date_updated: 2022-03-17T13:33:07Z
day: '01'
doi: 10.1016/0896-6273(92)90101-I
extern: '1'
external_id:
pmid:
- '1314625'
intvolume: ' 8'
issue: '4'
language:
- iso: eng
main_file_link:
- url: https://www.sciencedirect.com/science/article/pii/089662739290101I?via%3Dihub
month: '04'
oa_version: None
page: 811 - 819
pmid: 1
publication: Neuron
publication_identifier:
issn:
- 0896-6273
publication_status: published
publisher: Elsevier
publist_id: '4363'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Functional expression and tissue distribution of a novel receptor for vasoactive
intestinal polypeptide
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 8
year: '1992'
...
---
_id: '2535'
abstract:
- lang: eng
text: We report the molecular characterization of two novel rat helix-loop-helix
(HLH) proteins, designated HES-1 and HES-3, that show structural homology to the
Drosophila hairy and Enhancer of split [E(spl)] proteins, both of which are required
for normal neurogenesis. HES-1 mRNA, expressed in various tissues of both embryos
and adults, is present at a high level in the epithelial cells, including the
embryonal neuroepithelial cells, as well as in the mesoderm-derived tissues such
as the embryonal muscle. In contrast, HES-3 mRNA is produced exclusively in cerebellar
Purkinje cells. HES-1 represses transcription by binding to the N box, which is
a recognition sequence of E(spl) proteins. Interestingly, neither HES-1 nor HES-3
alone interacts efficiently with the E box, but each protein decreases the transcription
induced by E-box-binding HLH activators such as E47. Furthermore, HES-1 also inhibits
the functions of MyoD and MASH1 and effectively diminishes the myogenic conversion
of C3H10T1/2 cells induced by MyoD. These results suggest that HES-1 may play
an important role in mammalian development by negatively acting on the two different
sequences while HES-3 acts as a repressor in a specific type of neurons.
acknowledgement: "We thank Professor Noboru Mizuno for his kind help with in situ
hybridization experiments, Akira Uesugi and Dr. Chihiro\r\nAkazawa for photographic
assistance, Drs. Elizabeth Knust and Jose A. Campos-Ortega for communicating their
unpublished results, Dr. Shinji Fushiki for useful discussion, Dr. Mikio Nishizawa
and Professor Shigekazu Nagata for pMNT, Dr. David Baltimore for the E47 expression
vector, Drs. Yoichiro Nabeshima and Atsuko Fujisawa for the MyoD expression vector
and the reporter plasmid with the MCK enhancer, and Dr. Makoto Ishibashi for his
help in isolating the human E47 eDNA clone. This work was supported in part by research
grants from the Ministry of Education, Science, and Culture of Japan. The publication
costs of this article were defrayed in part by payment of page charges. This article
must therefore be hereby marked \"advertisement\" in accordance with 18 USC section
1734 solely to indicate this fact. \r\n"
article_processing_charge: No
article_type: original
author:
- first_name: Yoshiki
full_name: Sasai, Yoshiki
last_name: Sasai
- first_name: Ryoichiro
full_name: Kageyama, Ryoichiro
last_name: Kageyama
- first_name: Yoshiaki
full_name: Tagawa, Yoshiaki
last_name: Tagawa
- first_name: Ryuichi
full_name: Shigemoto, Ryuichi
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Shigetada
full_name: Nakanishi, Shigetada
last_name: Nakanishi
citation:
ama: Sasai Y, Kageyama R, Tagawa Y, Shigemoto R, Nakanishi S. Two mammalian helix-loop-helix
factors structurally related to Drosophila hairy and Enhancer of split. Genes
and Development. 1992;6(12 B):2620-2634. doi:10.1101/gad.6.12b.2620
apa: Sasai, Y., Kageyama, R., Tagawa, Y., Shigemoto, R., & Nakanishi, S. (1992).
Two mammalian helix-loop-helix factors structurally related to Drosophila hairy
and Enhancer of split. Genes and Development. Cold Spring Harbor Laboratory
Press. https://doi.org/10.1101/gad.6.12b.2620
chicago: Sasai, Yoshiki, Ryoichiro Kageyama, Yoshiaki Tagawa, Ryuichi Shigemoto,
and Shigetada Nakanishi. “Two Mammalian Helix-Loop-Helix Factors Structurally
Related to Drosophila Hairy and Enhancer of Split.” Genes and Development.
Cold Spring Harbor Laboratory Press, 1992. https://doi.org/10.1101/gad.6.12b.2620.
ieee: Y. Sasai, R. Kageyama, Y. Tagawa, R. Shigemoto, and S. Nakanishi, “Two mammalian
helix-loop-helix factors structurally related to Drosophila hairy and Enhancer
of split,” Genes and Development, vol. 6, no. 12 B. Cold Spring Harbor
Laboratory Press, pp. 2620–2634, 1992.
ista: Sasai Y, Kageyama R, Tagawa Y, Shigemoto R, Nakanishi S. 1992. Two mammalian
helix-loop-helix factors structurally related to Drosophila hairy and Enhancer
of split. Genes and Development. 6(12 B), 2620–2634.
mla: Sasai, Yoshiki, et al. “Two Mammalian Helix-Loop-Helix Factors Structurally
Related to Drosophila Hairy and Enhancer of Split.” Genes and Development,
vol. 6, no. 12 B, Cold Spring Harbor Laboratory Press, 1992, pp. 2620–34, doi:10.1101/gad.6.12b.2620.
short: Y. Sasai, R. Kageyama, Y. Tagawa, R. Shigemoto, S. Nakanishi, Genes and Development
6 (1992) 2620–2634.
date_created: 2018-12-11T11:58:15Z
date_published: 1992-01-01T00:00:00Z
date_updated: 2022-03-17T14:52:29Z
day: '01'
doi: 10.1101/gad.6.12b.2620
extern: '1'
external_id:
pmid:
- '1340473'
intvolume: ' 6'
issue: 12 B
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://genesdev.cshlp.org/content/6/12b/2620
month: '01'
oa: 1
oa_version: Published Version
page: 2620 - 2634
pmid: 1
publication: Genes and Development
publication_identifier:
issn:
- 0890-9369
publication_status: published
publisher: Cold Spring Harbor Laboratory Press
publist_id: '4364'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Two mammalian helix-loop-helix factors structurally related to Drosophila hairy
and Enhancer of split
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 6
year: '1992'
...
---
_id: '2714'
article_processing_charge: No
article_type: original
author:
- first_name: László
full_name: Erdös, László
id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
last_name: Erdös
orcid: 0000-0001-5366-9603
citation:
ama: Erdös L. On some problems of P. Turán concerning power sums of complex numbers.
Acta Mathematica Hungarica. 1992;59(1-2):11-24. doi:10.1007/BF00052086
apa: Erdös, L. (1992). On some problems of P. Turán concerning power sums of complex
numbers. Acta Mathematica Hungarica. Springer. https://doi.org/10.1007/BF00052086
chicago: Erdös, László. “On Some Problems of P. Turán Concerning Power Sums of Complex
Numbers.” Acta Mathematica Hungarica. Springer, 1992. https://doi.org/10.1007/BF00052086.
ieee: L. Erdös, “On some problems of P. Turán concerning power sums of complex numbers,”
Acta Mathematica Hungarica, vol. 59, no. 1–2. Springer, pp. 11–24, 1992.
ista: Erdös L. 1992. On some problems of P. Turán concerning power sums of complex
numbers. Acta Mathematica Hungarica. 59(1–2), 11–24.
mla: Erdös, László. “On Some Problems of P. Turán Concerning Power Sums of Complex
Numbers.” Acta Mathematica Hungarica, vol. 59, no. 1–2, Springer, 1992,
pp. 11–24, doi:10.1007/BF00052086.
short: L. Erdös, Acta Mathematica Hungarica 59 (1992) 11–24.
date_created: 2018-12-11T11:59:13Z
date_published: 1992-03-01T00:00:00Z
date_updated: 2022-03-16T15:33:08Z
day: '01'
doi: 10.1007/BF00052086
extern: '1'
intvolume: ' 59'
issue: 1-2
language:
- iso: eng
main_file_link:
- url: https://link.springer.com/article/10.1007/BF00052086
month: '03'
oa_version: None
page: 11 - 24
publication: Acta Mathematica Hungarica
publication_identifier:
issn:
- 0001-5954
publication_status: published
publisher: Springer
publist_id: '4182'
quality_controlled: '1'
scopus_import: '1'
status: public
title: On some problems of P. Turán concerning power sums of complex numbers
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 59
year: '1992'
...
---
_id: '2722'
abstract:
- lang: eng
text: 'A version of the one-dimensional Rayleigh gas is considered: a point particle
of mass M (molecule), confined to the unit interval [0,1], is surrounded by an
infinite ideal gas of point particles of mass 1 (atoms). The molecule interacts
with the atoms and with the walls via elastic collision. Central limit theorems
are proved for a wide class of additive functionals of this system (e.g. the number
of collisions with the walls and the total length of the molecular path).'
acknowledgement: "The authors are very grateful to D. Szasz and A. Kramli for valuable
discussions and their encouragement. We are also indebted to D. Dϋrr for his comments
and suggestions.\r\n"
article_processing_charge: No
article_type: original
author:
- first_name: László
full_name: Erdös, László
id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
last_name: Erdös
orcid: 0000-0001-5366-9603
- first_name: Dao
full_name: Tuyen, Dao
last_name: Tuyen
citation:
ama: Erdös L, Tuyen D. Central limit theorems for the one-dimensional Rayleigh gas
with semipermeable barriers. Communications in Mathematical Physics. 1992;143(3):451-466.
doi:10.1007/BF02099260
apa: Erdös, L., & Tuyen, D. (1992). Central limit theorems for the one-dimensional
Rayleigh gas with semipermeable barriers. Communications in Mathematical Physics.
Springer. https://doi.org/10.1007/BF02099260
chicago: Erdös, László, and Dao Tuyen. “Central Limit Theorems for the One-Dimensional
Rayleigh Gas with Semipermeable Barriers.” Communications in Mathematical Physics.
Springer, 1992. https://doi.org/10.1007/BF02099260.
ieee: L. Erdös and D. Tuyen, “Central limit theorems for the one-dimensional Rayleigh
gas with semipermeable barriers,” Communications in Mathematical Physics,
vol. 143, no. 3. Springer, pp. 451–466, 1992.
ista: Erdös L, Tuyen D. 1992. Central limit theorems for the one-dimensional Rayleigh
gas with semipermeable barriers. Communications in Mathematical Physics. 143(3),
451–466.
mla: Erdös, László, and Dao Tuyen. “Central Limit Theorems for the One-Dimensional
Rayleigh Gas with Semipermeable Barriers.” Communications in Mathematical Physics,
vol. 143, no. 3, Springer, 1992, pp. 451–66, doi:10.1007/BF02099260.
short: L. Erdös, D. Tuyen, Communications in Mathematical Physics 143 (1992) 451–466.
date_created: 2018-12-11T11:59:15Z
date_published: 1992-01-01T00:00:00Z
date_updated: 2022-03-16T14:24:12Z
day: '01'
doi: 10.1007/BF02099260
extern: '1'
intvolume: ' 143'
issue: '3'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://projecteuclid.org/journals/communications-in-mathematical-physics/volume-143/issue-3/Central-limit-theorems-for-the-one-dimensional-Rayleigh-gas-with/cmp/1104249076.full
month: '01'
oa: 1
oa_version: Published Version
page: 451 - 466
publication: Communications in Mathematical Physics
publication_identifier:
issn:
- 0010-3616
publication_status: published
publisher: Springer
publist_id: '4170'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Central limit theorems for the one-dimensional Rayleigh gas with semipermeable
barriers
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 143
year: '1992'
...
---
_id: '1946'
abstract:
- lang: eng
text: An ultra-low dose (10-14 M) of opioid peptide [D-Ala2]methionine enkephalinamide
(DAMEA) is found to exert an inhibitory effect on the production of reactive oxygen
species (respiratory burst) in human neutrophils. The validity of this phenomenon
has been verified in a series of studies that comprised 30 experiments. The inhibition
has proved to be statistically significant (P<0.001). The dose-response dependence
of the effect (10-15-10-9 M) followed a characteristic biphasic pattern (with
the maximum effect at ultra-low doses). An opioid antagonist, naloxone partially
blocks the inhibitory effect, which indicates that the DAMEA action is at least
partially mediated by opioid receptors.
article_processing_charge: No
author:
- first_name: Sergei
full_name: Zaǐtsev, Sergei
last_name: Zaǐtsev
- first_name: Leonid A
full_name: Sazanov, Leonid A
id: 338D39FE-F248-11E8-B48F-1D18A9856A87
last_name: Sazanov
orcid: 0000-0002-0977-7989
- first_name: Aleksei
full_name: Koshkin, Aleksei
last_name: Koshkin
- first_name: Galina
full_name: Sud'Ina, Galina
last_name: Sud'Ina
- first_name: Sergei
full_name: Varfolomeev, Sergei
last_name: Varfolomeev
citation:
ama: Zaǐtsev S, Sazanov LA, Koshkin A, Sud’Ina G, Varfolomeev S. Respiratory burst
inhibition in human neutrophils by ultra-low doses of [D-Ala2] methionine enkephalinamide.
FEBS Letters. 1991;291(1):84-86. doi:10.1016/0014-5793(91)81109-L
apa: Zaǐtsev, S., Sazanov, L. A., Koshkin, A., Sud’Ina, G., & Varfolomeev, S.
(1991). Respiratory burst inhibition in human neutrophils by ultra-low doses of
[D-Ala2] methionine enkephalinamide. FEBS Letters. Elsevier. https://doi.org/10.1016/0014-5793(91)81109-L
chicago: Zaǐtsev, Sergei, Leonid A Sazanov, Aleksei Koshkin, Galina Sud’Ina, and
Sergei Varfolomeev. “Respiratory Burst Inhibition in Human Neutrophils by Ultra-Low
Doses of [D-Ala2] Methionine Enkephalinamide.” FEBS Letters. Elsevier,
1991. https://doi.org/10.1016/0014-5793(91)81109-L.
ieee: S. Zaǐtsev, L. A. Sazanov, A. Koshkin, G. Sud’Ina, and S. Varfolomeev, “Respiratory
burst inhibition in human neutrophils by ultra-low doses of [D-Ala2] methionine
enkephalinamide,” FEBS Letters, vol. 291, no. 1. Elsevier, pp. 84–86, 1991.
ista: Zaǐtsev S, Sazanov LA, Koshkin A, Sud’Ina G, Varfolomeev S. 1991. Respiratory
burst inhibition in human neutrophils by ultra-low doses of [D-Ala2] methionine
enkephalinamide. FEBS Letters. 291(1), 84–86.
mla: Zaǐtsev, Sergei, et al. “Respiratory Burst Inhibition in Human Neutrophils
by Ultra-Low Doses of [D-Ala2] Methionine Enkephalinamide.” FEBS Letters,
vol. 291, no. 1, Elsevier, 1991, pp. 84–86, doi:10.1016/0014-5793(91)81109-L.
short: S. Zaǐtsev, L.A. Sazanov, A. Koshkin, G. Sud’Ina, S. Varfolomeev, FEBS Letters
291 (1991) 84–86.
date_created: 2018-12-11T11:54:51Z
date_published: 1991-10-07T00:00:00Z
date_updated: 2022-03-07T09:49:06Z
day: '07'
doi: 10.1016/0014-5793(91)81109-L
extern: '1'
external_id:
pmid:
- '1936255 '
intvolume: ' 291'
issue: '1'
language:
- iso: eng
main_file_link:
- url: https://www.sciencedirect.com/science/article/pii/001457939181109L
month: '10'
oa_version: None
page: 84 - 86
pmid: 1
publication: FEBS Letters
publication_identifier:
issn:
- 0014-2956
publication_status: published
publisher: Elsevier
publist_id: '5139'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Respiratory burst inhibition in human neutrophils by ultra-low doses of [D-Ala2]
methionine enkephalinamide
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 291
year: '1991'
...
---
_id: '3468'
abstract:
- lang: eng
text: "Two types of metabolically regulated K channels have been identified for
the first time in enzymatically demyelinated fibres of amphibian sciatic nerve
using the patch-clamp technique. A maxi K channel with a single-channel conductance
of 132 pS (105 mM K on both sides of the membrane, 15°C) is activated both by
micromolar concentrations of internal Ca and by depolarization. A second type
of K channel with a conductance of 44 pS is inhibited by intracellular adenosine
5'-triphosphate (ATP) with a half-maximal inhibitory concentration (IC50) of 35
μM. It is blocked by submicromolar concentrations of external glibenclamide. Both
channels are sensitive to external tetraethylammonium chloride (IC50 = 0.2 mM
for the maxi K channel and 4.2 mM for the ATP-sensitive channel). They may be
part of a complex feedback system regulating axonal excitability under various
metabolic conditions.\r\n"
article_processing_charge: No
article_type: original
author:
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
- first_name: Duk
full_name: Koh, Duk
last_name: Koh
- first_name: Knut
full_name: Kampe, Knut
last_name: Kampe
- first_name: Markus
full_name: Hermsteiner, Markus
last_name: Hermsteiner
- first_name: Werner
full_name: Vogel, Werner
last_name: Vogel
citation:
ama: 'Jonas PM, Koh D, Kampe K, Hermsteiner M, Vogel W. ATP-sensitive and Ca-activated
K channels in vertebrate axons: novel links between metabolism and excitability.
Pflügers Archiv : European Journal of Physiology. 1991;418(1-2):68-73.
doi:10.1007/BF00370453'
apa: 'Jonas, P. M., Koh, D., Kampe, K., Hermsteiner, M., & Vogel, W. (1991).
ATP-sensitive and Ca-activated K channels in vertebrate axons: novel links between
metabolism and excitability. Pflügers Archiv : European Journal of Physiology.
Springer. https://doi.org/10.1007/BF00370453'
chicago: 'Jonas, Peter M, Duk Koh, Knut Kampe, Markus Hermsteiner, and Werner Vogel.
“ATP-Sensitive and Ca-Activated K Channels in Vertebrate Axons: Novel Links between
Metabolism and Excitability.” Pflügers Archiv : European Journal of Physiology.
Springer, 1991. https://doi.org/10.1007/BF00370453.'
ieee: 'P. M. Jonas, D. Koh, K. Kampe, M. Hermsteiner, and W. Vogel, “ATP-sensitive
and Ca-activated K channels in vertebrate axons: novel links between metabolism
and excitability,” Pflügers Archiv : European Journal of Physiology, vol.
418, no. 1–2. Springer, pp. 68–73, 1991.'
ista: 'Jonas PM, Koh D, Kampe K, Hermsteiner M, Vogel W. 1991. ATP-sensitive and
Ca-activated K channels in vertebrate axons: novel links between metabolism and
excitability. Pflügers Archiv : European Journal of Physiology. 418(1–2), 68–73.'
mla: 'Jonas, Peter M., et al. “ATP-Sensitive and Ca-Activated K Channels in Vertebrate
Axons: Novel Links between Metabolism and Excitability.” Pflügers Archiv :
European Journal of Physiology, vol. 418, no. 1–2, Springer, 1991, pp. 68–73,
doi:10.1007/BF00370453.'
short: 'P.M. Jonas, D. Koh, K. Kampe, M. Hermsteiner, W. Vogel, Pflügers Archiv :
European Journal of Physiology 418 (1991) 68–73.'
date_created: 2018-12-11T12:03:29Z
date_published: 1991-01-01T00:00:00Z
date_updated: 2022-03-03T14:42:06Z
day: '01'
doi: 10.1007/BF00370453
extern: '1'
external_id:
pmid:
- '2041727'
intvolume: ' 418'
issue: 1-2
language:
- iso: eng
main_file_link:
- url: https://link.springer.com/article/10.1007/BF00370453
month: '01'
oa_version: None
page: 68 - 73
pmid: 1
publication: 'Pflügers Archiv : European Journal of Physiology'
publication_identifier:
eissn:
- 1432-2013
issn:
- 0031-6768
publication_status: published
publisher: Springer
publist_id: '2919'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'ATP-sensitive and Ca-activated K channels in vertebrate axons: novel links
between metabolism and excitability'
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 418
year: '1991'
...
---
_id: '3566'
abstract:
- lang: eng
text: This paper proves an O(m2/3n2/3 + m + n) upper bound on the number of incidences
between m points and n hyperplanes in four dimensions, assuming all points lie
on one side of each hyperplane and the points and hyperplanes satisfy certain
natural general position conditions. This result has application to various three-dimensional
combinatorial distance problems. For example, it implies the same upper bound
for the number of bichromatic minimum distance pairs in a set of m blue and n
red points in three-dimensional space. This improves the best previous bound for
this problem. © Springer-Verlag Berlin Heidelberg 1990.
alternative_title:
- DIMACS Series in Discrete Mathematics and Theoretical Computer Science
article_processing_charge: No
author:
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
- first_name: Micha
full_name: Sharir, Micha
last_name: Sharir
citation:
ama: 'Edelsbrunner H, Sharir M. A hyperplane incidence problem with applications
to counting distances. In: Applied Geometry and Discrete Mathematics: The Victor
Klee Festschrift. Vol 4. American Mathematical Society; 1991:253-263.'
apa: 'Edelsbrunner, H., & Sharir, M. (1991). A hyperplane incidence problem
with applications to counting distances. In Applied Geometry and Discrete Mathematics:
The Victor Klee Festschrift (Vol. 4, pp. 253–263). American Mathematical Society.'
chicago: 'Edelsbrunner, Herbert, and Micha Sharir. “A Hyperplane Incidence Problem
with Applications to Counting Distances.” In Applied Geometry and Discrete
Mathematics: The Victor Klee Festschrift, 4:253–63. American Mathematical
Society, 1991.'
ieee: 'H. Edelsbrunner and M. Sharir, “A hyperplane incidence problem with applications
to counting distances,” in Applied Geometry and Discrete Mathematics: The Victor
Klee Festschrift, vol. 4, American Mathematical Society, 1991, pp. 253–263.'
ista: 'Edelsbrunner H, Sharir M. 1991.A hyperplane incidence problem with applications
to counting distances. In: Applied Geometry and Discrete Mathematics: The Victor
Klee Festschrift. DIMACS Series in Discrete Mathematics and Theoretical Computer
Science, vol. 4, 253–263.'
mla: 'Edelsbrunner, Herbert, and Micha Sharir. “A Hyperplane Incidence Problem with
Applications to Counting Distances.” Applied Geometry and Discrete Mathematics:
The Victor Klee Festschrift, vol. 4, American Mathematical Society, 1991,
pp. 253–63.'
short: 'H. Edelsbrunner, M. Sharir, in:, Applied Geometry and Discrete Mathematics:
The Victor Klee Festschrift, American Mathematical Society, 1991, pp. 253–263.'
date_created: 2018-12-11T12:04:00Z
date_published: 1991-04-01T00:00:00Z
date_updated: 2022-03-03T13:27:01Z
day: '01'
extern: '1'
intvolume: ' 4'
language:
- iso: eng
main_file_link:
- url: http://www.cs.duke.edu/~edels/Papers/1991-B-01-HyperplaneIncidence.pdf
month: '04'
oa_version: None
page: 253 - 263
publication: 'Applied Geometry and Discrete Mathematics: The Victor Klee Festschrift'
publication_identifier:
isbn:
- 978-0897913850
publication_status: published
publisher: American Mathematical Society
publist_id: '2819'
quality_controlled: '1'
scopus_import: '1'
status: public
title: A hyperplane incidence problem with applications to counting distances
type: book_chapter
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 4
year: '1991'
...
---
_id: '3567'
abstract:
- lang: eng
text: 'Many computational geometry problems arc exceedingly more difficult if the
setting is the (three-dimensional real) space R3 rather than the plane . Most
often the reason for this striking increase in complexity is the appearance of
new geometric phenomena caused by one-dimensional objects in space. The intention
of recent studies on problems for lines in space is to shed light on these new
phenomena and their complexities. This paper reviews some of the most important
results and shows how they are related to problems in dimensions 2 and 5. '
acknowledgement: National Science Foundation under grant CCR-8921421.
alternative_title:
- DIAMCS Series in Discrete Mathematics and Theoretical Computer Science
article_processing_charge: No
author:
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
citation:
ama: 'Edelsbrunner H. Lines in space – A collection of results. In: Discrete
& Computational Geometry: Papers from the Dimacs Special Year. Vol 6.
Springer; 1991:77-93.'
apa: 'Edelsbrunner, H. (1991). Lines in space – A collection of results. In Discrete
& Computational Geometry: Papers from the Dimacs Special Year (Vol. 6,
pp. 77–93). Springer.'
chicago: 'Edelsbrunner, Herbert. “Lines in Space – A Collection of Results.” In
Discrete & Computational Geometry: Papers from the Dimacs Special Year,
6:77–93. Springer, 1991.'
ieee: 'H. Edelsbrunner, “Lines in space – A collection of results,” in Discrete
& Computational Geometry: Papers from the Dimacs Special Year, vol. 6,
Springer, 1991, pp. 77–93.'
ista: 'Edelsbrunner H. 1991.Lines in space – A collection of results. In: Discrete
& Computational Geometry: Papers from the Dimacs Special Year. DIAMCS Series
in Discrete Mathematics and Theoretical Computer Science, vol. 6, 77–93.'
mla: 'Edelsbrunner, Herbert. “Lines in Space – A Collection of Results.” Discrete
& Computational Geometry: Papers from the Dimacs Special Year, vol. 6,
Springer, 1991, pp. 77–93.'
short: 'H. Edelsbrunner, in:, Discrete & Computational Geometry: Papers from
the Dimacs Special Year, Springer, 1991, pp. 77–93.'
date_created: 2018-12-11T12:04:00Z
date_published: 1991-06-01T00:00:00Z
date_updated: 2022-03-03T10:48:15Z
day: '01'
extern: '1'
intvolume: ' 6'
language:
- iso: eng
main_file_link:
- url: https://pub.ist.ac.at/~edels/Papers/1991-B-02-LinesInSpaceACollection.pdf
month: '06'
oa_version: None
page: 77 - 93
publication: 'Discrete & Computational Geometry: Papers from the Dimacs Special Year'
publication_identifier:
isbn:
- '9780821865958'
publication_status: published
publisher: Springer
publist_id: '2818'
quality_controlled: '1'
status: public
title: Lines in space – A collection of results
type: book_chapter
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 6
year: '1991'
...
---
_id: '3646'
abstract:
- lang: eng
text: "We compare the pattern of morphological and electrophoretic variation in
the hybrid zone between Bombina bombina and B. variegata across two transects:
one near Cracow and one 200 km away, near Przemysl in southeastern Poland. Morphological
variation across the Przemysl transect had been surveyed more than 50 years ago;
though we found a significant shift at one site, there is no evidence for gross
movement over this period. Morphological and electrophoretic changes coincide,
and the average shape of the clines is the same across both transects. At the
center, most of the change in frequency of six diagnostic allozymes occurs within
w = 6.05 km (2-unit support limits 5.56-6.54 km). These steep gradients are generated
not by selection on the allozymes themselves, but by associations with other loci:
though these markers are unlinked, they are in strong linkage disequilibrium with
each other [R = D/ = 0.22 (0.15-0.29) at the center]. Disequilibria are broken
up as alleles diffuse away from the zone and flow into the new genetic background.
The net barrier to the flow of genes from bombina into variegata, which is generated
by these disequilibria, is B = 51 (22-81) km. The fitness of hybrids must be substantially
reduced to produce such a barrier [W̄H/W̄P = 0.58 (0.54-0.68)], and this selection
must be spread over many loci [N = 55 (26-88)]. Alleles introgress significantly
less far than would be expected from the age of the zone and the estimated dispersal
rate [σ = 0.99 (0.82-1.14) km gen.-1/2]: this implies selection of se = 0.37 (0.15-0.58)%
on the enzymes themselves. There is weak but significant linkage disequilibrium
well away from the center of the zone; this, together with the presence of parental
and F1 genotypes, suggests some long-range migration. However, such migration
is not likely to cause significant introgression.\r\n"
acknowledgement: This work was supported by grants from the Royal Society, the Nuffield
Foundation, the University of London Central Research Fund, and the Polish Academy
of Sciences (project MR-II.6). We also thank Dr. Jan Rafinski for help in collecting
toads.
article_processing_charge: No
article_type: original
author:
- first_name: Jacek
full_name: Szymura, Jacek
last_name: Szymura
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
citation:
ama: 'Szymura J, Barton NH. The genetic structure of the hybrid zone between the
fire-bellied toads Bombina bombina and B. variegata: comparisons between transects
and between loci. Evolution. 1991;45(2):237-261. doi:10.1111/j.1558-5646.1991.tb04400.x'
apa: 'Szymura, J., & Barton, N. H. (1991). The genetic structure of the hybrid
zone between the fire-bellied toads Bombina bombina and B. variegata: comparisons
between transects and between loci. Evolution. Wiley-Blackwell. https://doi.org/10.1111/j.1558-5646.1991.tb04400.x'
chicago: 'Szymura, Jacek, and Nicholas H Barton. “The Genetic Structure of the Hybrid
Zone between the Fire-Bellied Toads Bombina Bombina and B. Variegata: Comparisons
between Transects and between Loci.” Evolution. Wiley-Blackwell, 1991.
https://doi.org/10.1111/j.1558-5646.1991.tb04400.x.'
ieee: 'J. Szymura and N. H. Barton, “The genetic structure of the hybrid zone between
the fire-bellied toads Bombina bombina and B. variegata: comparisons between transects
and between loci,” Evolution, vol. 45, no. 2. Wiley-Blackwell, pp. 237–261,
1991.'
ista: 'Szymura J, Barton NH. 1991. The genetic structure of the hybrid zone between
the fire-bellied toads Bombina bombina and B. variegata: comparisons between transects
and between loci. Evolution. 45(2), 237–261.'
mla: 'Szymura, Jacek, and Nicholas H. Barton. “The Genetic Structure of the Hybrid
Zone between the Fire-Bellied Toads Bombina Bombina and B. Variegata: Comparisons
between Transects and between Loci.” Evolution, vol. 45, no. 2, Wiley-Blackwell,
1991, pp. 237–61, doi:10.1111/j.1558-5646.1991.tb04400.x.'
short: J. Szymura, N.H. Barton, Evolution 45 (1991) 237–261.
date_created: 2018-12-11T12:04:25Z
date_published: 1991-03-01T00:00:00Z
date_updated: 2022-03-02T15:50:09Z
day: '01'
doi: 10.1111/j.1558-5646.1991.tb04400.x
extern: '1'
external_id:
pmid:
- '28567861 '
intvolume: ' 45'
issue: '2'
language:
- iso: eng
main_file_link:
- url: ' http://www.jstor.org/stable/2409660'
month: '03'
oa_version: None
page: 237 - 261
pmid: 1
publication: Evolution
publication_identifier:
eissn:
- 1558-5646
issn:
- 0014-3820
publication_status: published
publisher: Wiley-Blackwell
publist_id: '2737'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'The genetic structure of the hybrid zone between the fire-bellied toads Bombina
bombina and B. variegata: comparisons between transects and between loci'
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 45
year: '1991'
...
---
_id: '3647'
abstract:
- lang: eng
text: A method is developed that describes the effects on an arbitrary number of
autosomal loci of selection on haploid and diploid stages, of nonrandom mating
between haploid individuals, and of recombination. We provide exact recursions
for the dynamics of allele frequencies and linkage disequilibria (nonrandom associations
of alleles across loci). When selection is weak relative to recombination, our
recursions provide simple approximations for the linkage disequilibria among arbitrary
combinations of loci. We show how previous models of sex-independent natural selection
on diploids, assortative mating between haploids, and sexual selection on haploids
can be analyzed in this framework. Using our weak-selection approximations, we
derive new results concerning the coevolution of male traits and female preferences
under natural and sexual selection. In particular, we provide general expressions
for the intensity of linkage-disequilibrium induced selection experienced by loci
that contribute to female preferences for specific male traits. Our general results
support the previous observation that these indirect selection forces are so weak
that they are unlikely to dominate the evolution of preference-producing loci.
acknowledgement: "BENGT OLLE BENGTSSON, JERRY COYNE, RICHARD GOMULKIEWICZ, CHUCK LANGLEY,
LINDA PARTRIDGE, MONTY SLATKIN, and NEAL TAYLOR gave helpful comments on preliminary
versions, which are gratefully acknowledged. We are particularly indebted to DICK
HUDSON, MARK KIRKPATRICK and TOM NAGYLAKI for\r\nhelping to eliminate many obscurities.
This work was supported by the Science and Engineering Research Council (GR/C/91529,
GR/E/08507), the National Science Foundation (BSR-8866548), the Institute of Theoretical
Dynamics and the Center for Population Biology at the University of California,
Davis, and by the Swedish Natural Science Research Council. "
article_processing_charge: No
article_type: original
author:
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
- first_name: Michael
full_name: Turelli, Michael
last_name: Turelli
citation:
ama: Barton NH, Turelli M. Natural and sexual selection on many loci. Genetics.
1991;127(1):229-255. doi:10.1093/genetics/127.1.229
apa: Barton, N. H., & Turelli, M. (1991). Natural and sexual selection on many
loci. Genetics. Genetics Society of America. https://doi.org/10.1093/genetics/127.1.229
chicago: Barton, Nicholas H, and Michael Turelli. “Natural and Sexual Selection
on Many Loci.” Genetics. Genetics Society of America, 1991. https://doi.org/10.1093/genetics/127.1.229.
ieee: N. H. Barton and M. Turelli, “Natural and sexual selection on many loci,”
Genetics, vol. 127, no. 1. Genetics Society of America, pp. 229–255, 1991.
ista: Barton NH, Turelli M. 1991. Natural and sexual selection on many loci. Genetics.
127(1), 229–255.
mla: Barton, Nicholas H., and Michael Turelli. “Natural and Sexual Selection on
Many Loci.” Genetics, vol. 127, no. 1, Genetics Society of America, 1991,
pp. 229–55, doi:10.1093/genetics/127.1.229.
short: N.H. Barton, M. Turelli, Genetics 127 (1991) 229–255.
date_created: 2018-12-11T12:04:25Z
date_published: 1991-01-01T00:00:00Z
date_updated: 2022-03-02T15:23:02Z
day: '01'
doi: 10.1093/genetics/127.1.229
extern: '1'
external_id:
pmid:
- '2016044'
intvolume: ' 127'
issue: '1'
language:
- iso: eng
main_file_link:
- url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1204308/
month: '01'
oa_version: None
page: 229 - 255
pmid: 1
publication: Genetics
publication_identifier:
issn:
- 0016-6731
publication_status: published
publisher: Genetics Society of America
publist_id: '2736'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Natural and sexual selection on many loci
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 127
year: '1991'
...
---
_id: '3648'
abstract:
- lang: eng
text: 'We investigate the probability of fixation of a chromosome rearrangement
in a subdivided population, concentrating on the limit where migration is so large
relative to selection (m ≫ s) that the population can be thought of as being continuously
distributed. We study two demes, and one- and two-dimensional populations. For
two demes, the probability of fixation in the limit of high migration approximates
that of a population with twice the size of a single deme: migration therefore
greatly reduces the fixation probability. However, this behavior does not extend
to a large array of demes. Then, the fixation probability depends primarily on
neighborhood size (Nb), and may be appreciable even with strong selection and
free gene flow (≈exp(-B·Nb) in one dimension, ≈exp(-B\cdotNb) in two dimensions).
Our results are close to those for the more tractable case of a polygenic character
under disruptive selection.'
article_processing_charge: No
article_type: original
author:
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
- first_name: Shahin
full_name: Rouhani, Shahin
last_name: Rouhani
citation:
ama: Barton NH, Rouhani S. The probability of fixation of a new karyotype in a continuous
population. Evolution. 1991;45(3):499-517. doi:10.1111/j.1558-5646.1991.tb04326.x
apa: Barton, N. H., & Rouhani, S. (1991). The probability of fixation of a new
karyotype in a continuous population. Evolution. Wiley-Blackwell. https://doi.org/10.1111/j.1558-5646.1991.tb04326.x
chicago: Barton, Nicholas H, and Shahin Rouhani. “The Probability of Fixation of
a New Karyotype in a Continuous Population.” Evolution. Wiley-Blackwell,
1991. https://doi.org/10.1111/j.1558-5646.1991.tb04326.x.
ieee: N. H. Barton and S. Rouhani, “The probability of fixation of a new karyotype
in a continuous population,” Evolution, vol. 45, no. 3. Wiley-Blackwell,
pp. 499–517, 1991.
ista: Barton NH, Rouhani S. 1991. The probability of fixation of a new karyotype
in a continuous population. Evolution. 45(3), 499–517.
mla: Barton, Nicholas H., and Shahin Rouhani. “The Probability of Fixation of a
New Karyotype in a Continuous Population.” Evolution, vol. 45, no. 3, Wiley-Blackwell,
1991, pp. 499–517, doi:10.1111/j.1558-5646.1991.tb04326.x.
short: N.H. Barton, S. Rouhani, Evolution 45 (1991) 499–517.
date_created: 2018-12-11T12:04:25Z
date_published: 1991-05-01T00:00:00Z
date_updated: 2022-03-02T10:37:19Z
day: '01'
doi: 10.1111/j.1558-5646.1991.tb04326.x
extern: '1'
external_id:
pmid:
- '28568824'
intvolume: ' 45'
issue: '3'
language:
- iso: eng
main_file_link:
- url: http://www.jstor.org/stable/2409908
month: '05'
oa_version: None
page: 499 - 517
pmid: 1
publication: Evolution
publication_identifier:
eissn:
- 1558-5646
issn:
- 0014-3820
publication_status: published
publisher: Wiley-Blackwell
publist_id: '2735'
quality_controlled: '1'
status: public
title: The probability of fixation of a new karyotype in a continuous population
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 45
year: '1991'
...
---
_id: '4051'
abstract:
- lang: eng
text: An algorithm is presented that constructs the convex hull of a set of n points
in three dimensions in worst-case time O(n log2h) and storage O(n), where h is
the number of extreme points. This is an improvement of the O(nh) time gift-wrapping
algorithm and, for certain values of h, of the O(n log n) time divide-and-conquer
algorithm.
article_processing_charge: No
article_type: original
author:
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
- first_name: Weiping
full_name: Shi, Weiping
last_name: Shi
citation:
ama: Edelsbrunner H, Shi W. An O(n log^2 h) time algorithm for the three-dimensional
convex hull problem. SIAM Journal on Computing. 1991;20(2):259-269. doi:10.1137/0220016
apa: Edelsbrunner, H., & Shi, W. (1991). An O(n log^2 h) time algorithm for
the three-dimensional convex hull problem. SIAM Journal on Computing. SIAM.
https://doi.org/10.1137/0220016
chicago: Edelsbrunner, Herbert, and Weiping Shi. “An O(n Log^2 h) Time Algorithm
for the Three-Dimensional Convex Hull Problem.” SIAM Journal on Computing.
SIAM, 1991. https://doi.org/10.1137/0220016
.
ieee: H. Edelsbrunner and W. Shi, “An O(n log^2 h) time algorithm for the three-dimensional
convex hull problem,” SIAM Journal on Computing, vol. 20, no. 2. SIAM,
pp. 259–269, 1991.
ista: Edelsbrunner H, Shi W. 1991. An O(n log^2 h) time algorithm for the three-dimensional
convex hull problem. SIAM Journal on Computing. 20(2), 259–269.
mla: Edelsbrunner, Herbert, and Weiping Shi. “An O(n Log^2 h) Time Algorithm for
the Three-Dimensional Convex Hull Problem.” SIAM Journal on Computing,
vol. 20, no. 2, SIAM, 1991, pp. 259–69, doi:10.1137/0220016 .
short: H. Edelsbrunner, W. Shi, SIAM Journal on Computing 20 (1991) 259–269.
date_created: 2018-12-11T12:06:39Z
date_published: 1991-04-01T00:00:00Z
date_updated: 2022-03-02T10:18:31Z
day: '01'
doi: '10.1137/0220016 '
extern: '1'
intvolume: ' 20'
issue: '2'
language:
- iso: eng
main_file_link:
- url: https://epubs.siam.org/doi/10.1137/0220016
month: '04'
oa_version: None
page: 259 - 269
publication: SIAM Journal on Computing
publication_identifier:
eissn:
- 1095-7111
issn:
- 0097-5397
publication_status: published
publisher: SIAM
publist_id: '2072'
quality_controlled: '1'
status: public
title: An O(n log^2 h) time algorithm for the three-dimensional convex hull problem
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 20
year: '1991'
...
---
_id: '4052'
abstract:
- lang: eng
text: This paper describes an effective procedure for stratifying a real semi-algebraic
set into cells of constant description size. The attractive feature of our method
is that the number of cells produced is singly exponential in the number of input
variables. This compares favorably with the doubly exponential size of Collins'
decomposition. Unlike Collins' construction, however, our scheme does not produce
a cell complex but only a smooth stratification. Nevertheless, we are able to
apply our results in interesting ways to problems of point location and geometric
optimization.
acknowledgement: The authors wish to thank DEC/Systems Research Center and DEC/Paris
Research Laboratory, where part of this research was conducted. For individual support,
Bernard Chazelle acknowledges the National Science Foundation for supporting this
research in part under Grant CCR-8700917. Herbert Edelsbrunner acknowledges the
support of the National Science Foundation under Grant CCR-8714565. Micha Sharir
acknowledges the Office of Naval Research under Grant N00014-87-K-0129, the National
Science Foundation under Grant No. NSF-DCR-83-20085, grants from the Digital Equipment
Corporation and the IBM Corporation, and a research grant from the US-Israeli Binational
Science Foundation.
article_processing_charge: No
article_type: original
author:
- first_name: Bernard
full_name: Chazelle, Bernard
last_name: Chazelle
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
- first_name: Leonidas
full_name: Guibas, Leonidas
last_name: Guibas
- first_name: Micha
full_name: Sharir, Micha
last_name: Sharir
citation:
ama: Chazelle B, Edelsbrunner H, Guibas L, Sharir M. A singly exponential stratification
scheme for real semi-algebraic varieties and its applications. Theoretical
Computer Science. 1991;84(1):77-105. doi:10.1016/0304-3975(91)90261-Y
apa: Chazelle, B., Edelsbrunner, H., Guibas, L., & Sharir, M. (1991). A singly
exponential stratification scheme for real semi-algebraic varieties and its applications.
Theoretical Computer Science. Elsevier. https://doi.org/10.1016/0304-3975(91)90261-Y
chicago: Chazelle, Bernard, Herbert Edelsbrunner, Leonidas Guibas, and Micha Sharir.
“A Singly Exponential Stratification Scheme for Real Semi-Algebraic Varieties
and Its Applications.” Theoretical Computer Science. Elsevier, 1991. https://doi.org/10.1016/0304-3975(91)90261-Y.
ieee: B. Chazelle, H. Edelsbrunner, L. Guibas, and M. Sharir, “A singly exponential
stratification scheme for real semi-algebraic varieties and its applications,”
Theoretical Computer Science, vol. 84, no. 1. Elsevier, pp. 77–105, 1991.
ista: Chazelle B, Edelsbrunner H, Guibas L, Sharir M. 1991. A singly exponential
stratification scheme for real semi-algebraic varieties and its applications.
Theoretical Computer Science. 84(1), 77–105.
mla: Chazelle, Bernard, et al. “A Singly Exponential Stratification Scheme for Real
Semi-Algebraic Varieties and Its Applications.” Theoretical Computer Science,
vol. 84, no. 1, Elsevier, 1991, pp. 77–105, doi:10.1016/0304-3975(91)90261-Y.
short: B. Chazelle, H. Edelsbrunner, L. Guibas, M. Sharir, Theoretical Computer
Science 84 (1991) 77–105.
date_created: 2018-12-11T12:06:39Z
date_published: 1991-07-22T00:00:00Z
date_updated: 2022-03-02T10:23:58Z
day: '22'
doi: 10.1016/0304-3975(91)90261-Y
extern: '1'
intvolume: ' 84'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.sciencedirect.com/science/article/pii/030439759190261Y?via%3Dihub
month: '07'
oa: 1
oa_version: Published Version
page: 77 - 105
publication: Theoretical Computer Science
publication_identifier:
eissn:
- 1879-2294
issn:
- 0304-3975
publication_status: published
publisher: Elsevier
publist_id: '2073'
quality_controlled: '1'
scopus_import: '1'
status: public
title: A singly exponential stratification scheme for real semi-algebraic varieties
and its applications
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 84
year: '1991'
...
---
_id: '4054'
abstract:
- lang: eng
text: The zone theorem for an arrangement of n hyperplanes in d-dimensional real
space says that the total number of faces bounding the cells intersected by another
hyperplane is O(n d–1). This result is the basis of a time-optimal incremental
algorithm that constructs a hyperplane arrangement and has a host of other algorithmic
and combinatorial applications. Unfortunately, the original proof of the zone
theorem, for d ge 3, turned out to contain a serious and irreparable error. This
paper presents a new proof of the theorem. Our proof is based on an inductive
argument, which also applies in the case of pseudo-hyperplane arrangements. We
also briefly discuss the fallacies of the old proof along with some ways of partially
saving that approach.
acknowledgement: Research of Herbert Edelsbrunner was supported by the National Science
Foundation under grant CCR-89-21421. Raimund Seidel acknowledges support by an NSF
Presidential Young Investigator Grant CCR-90-58440. Micha Sharir has been supported
by ONR Grant N00014-90-J-1284, by NSF Grant CCR-89-01484, and by grants from the
U.S.-Israeli Binational Science Foundation, the German-Israeli Foundation for Scientific
Research and Development, and the Fund for Basic Research of the Israeli Academy
of Sciences.
alternative_title:
- LNCS
article_processing_charge: No
author:
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
- first_name: Raimund
full_name: Seidel, Raimund
last_name: Seidel
- first_name: Micha
full_name: Sharir, Micha
last_name: Sharir
citation:
ama: 'Edelsbrunner H, Seidel R, Sharir M. On the zone theorem for hyperplane arrangements.
In: Vol 555. Springer; 1991:108-123. doi:10.1007/BFb0038185'
apa: Edelsbrunner, H., Seidel, R., & Sharir, M. (1991). On the zone theorem
for hyperplane arrangements (Vol. 555, pp. 108–123). Presented at the New Results
and New Trends in Computer Science , Springer. https://doi.org/10.1007/BFb0038185
chicago: Edelsbrunner, Herbert, Raimund Seidel, and Micha Sharir. “On the Zone Theorem
for Hyperplane Arrangements,” 555:108–23. Springer, 1991. https://doi.org/10.1007/BFb0038185.
ieee: H. Edelsbrunner, R. Seidel, and M. Sharir, “On the zone theorem for hyperplane
arrangements,” presented at the New Results and New Trends in Computer Science
, 1991, vol. 555, pp. 108–123.
ista: Edelsbrunner H, Seidel R, Sharir M. 1991. On the zone theorem for hyperplane
arrangements. New Results and New Trends in Computer Science , LNCS, vol. 555,
108–123.
mla: Edelsbrunner, Herbert, et al. On the Zone Theorem for Hyperplane Arrangements.
Vol. 555, Springer, 1991, pp. 108–23, doi:10.1007/BFb0038185.
short: H. Edelsbrunner, R. Seidel, M. Sharir, in:, Springer, 1991, pp. 108–123.
conference:
name: 'New Results and New Trends in Computer Science '
date_created: 2018-12-11T12:06:40Z
date_published: 1991-11-13T00:00:00Z
date_updated: 2022-02-28T15:13:37Z
day: '13'
doi: 10.1007/BFb0038185
extern: '1'
intvolume: ' 555'
language:
- iso: eng
main_file_link:
- url: https://link.springer.com/chapter/10.1007/BFb0038185
month: '11'
oa_version: None
page: 108 - 123
publication_status: published
publisher: Springer
publist_id: '2068'
quality_controlled: '1'
status: public
title: On the zone theorem for hyperplane arrangements
type: conference
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 555
year: '1991'
...