---
_id: '11926'
abstract:
- lang: eng
text: "We present the first polylog-competitive online algorithm for the general
multicast problem in the throughput model. The ratio of the number of requests
accepted by the optimum offline alaorithm to the exoected number of reauests accepted
by our algorithm is O(jlog n + log log M)(log n + log M) log n), where M is the
number of multicast groups and n is the number of nodes in the nraoh. We show
that this is close to optimum by presenting-an*R(log nlog M) lower\r\nbound on
this ratio for anv randomized online algorithm against an oblivious adversary,
when M is much lar&r than the link capacities. Our lower bound applies even in
the restricted case where the link capacities are much larger than bandwidth requested
by a single multicast. We also present a simple proof showing that it is impossible
to be competitive against an adaptive online adversary. As in the previous online
routing algorithms, our algorithm uses edge-costs when deciding on which is the
best path to use. In contrast to the nrevious comnetitive aleorithms in the throughput
modei, our cost is-not a direct function of the edne load. The new cost definition
allows us to decouple the effects of routing and admission decisions of different
multicast groups. "
article_processing_charge: No
author:
- first_name: Ashish
full_name: Goel, Ashish
last_name: Goel
- first_name: Monika H
full_name: Henzinger, Monika H
id: 540c9bbd-f2de-11ec-812d-d04a5be85630
last_name: Henzinger
orcid: 0000-0002-5008-6530
- first_name: Serge
full_name: Plotkin, Serge
last_name: Plotkin
citation:
ama: 'Goel A, Henzinger MH, Plotkin S. An online throughput-competitive algorithm
for multicast routing and admission control. In: 9th Annual ACM SIAM Symposium
on Discrete Algorithms. Society for Industrial and Applied Mathematics; 1998:97-106.'
apa: 'Goel, A., Henzinger, M. H., & Plotkin, S. (1998). An online throughput-competitive
algorithm for multicast routing and admission control. In 9th Annual ACM SIAM
Symposium on Discrete Algorithms (pp. 97–106). San Francisco, CA, United States:
Society for Industrial and Applied Mathematics.'
chicago: Goel, Ashish, Monika H Henzinger, and Serge Plotkin. “An Online Throughput-Competitive
Algorithm for Multicast Routing and Admission Control.” In 9th Annual ACM SIAM
Symposium on Discrete Algorithms, 97–106. Society for Industrial and Applied
Mathematics, 1998.
ieee: A. Goel, M. H. Henzinger, and S. Plotkin, “An online throughput-competitive
algorithm for multicast routing and admission control,” in 9th Annual ACM SIAM
Symposium on Discrete Algorithms, San Francisco, CA, United States, 1998,
pp. 97–106.
ista: 'Goel A, Henzinger MH, Plotkin S. 1998. An online throughput-competitive algorithm
for multicast routing and admission control. 9th Annual ACM SIAM Symposium on
Discrete Algorithms. SODA: Symposium on Discrete Algorithms, 97–106.'
mla: Goel, Ashish, et al. “An Online Throughput-Competitive Algorithm for Multicast
Routing and Admission Control.” 9th Annual ACM SIAM Symposium on Discrete Algorithms,
Society for Industrial and Applied Mathematics, 1998, pp. 97–106.
short: A. Goel, M.H. Henzinger, S. Plotkin, in:, 9th Annual ACM SIAM Symposium on
Discrete Algorithms, Society for Industrial and Applied Mathematics, 1998, pp.
97–106.
conference:
end_date: 1998-01-27
location: San Francisco, CA, United States
name: 'SODA: Symposium on Discrete Algorithms'
start_date: 1998-01-25
date_created: 2022-08-19T06:22:30Z
date_published: 1998-01-01T00:00:00Z
date_updated: 2023-02-21T16:27:22Z
day: '01'
extern: '1'
language:
- iso: eng
month: '01'
oa_version: None
page: 97-106
publication: 9th Annual ACM SIAM Symposium on Discrete Algorithms
publication_identifier:
isbn:
- '0898714109'
publication_status: published
publisher: Society for Industrial and Applied Mathematics
quality_controlled: '1'
related_material:
record:
- id: '11763'
relation: later_version
status: public
scopus_import: '1'
status: public
title: An online throughput-competitive algorithm for multicast routing and admission
control
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '1998'
...
---
_id: '2583'
abstract:
- lang: eng
text: Substance P receptor (SPR)-immunoreactive neurons projecting to the periaqueductal
gray (PAG) were examined in the rat spinal trigeminal nucleus and spinal cord
by a retrograde tracing method combined with immunofluorescence histochemistry.
After injection of Fluoro-gold (FG) into the PAG, SPR-immunoreactive neurons labeled
with FG were observed mainly in the lateral spinal nucleus and lamina I of the
medullary and spinal dorsal horns and additionally in laminae V and X of the spinal
cord.
acknowledgement: "The authors are grateful for the support of Dr Kajitaro Morita of
the Morita Clinic of Internal Medicine and Pediatrics at Kadoma, Osaka and for the
help of Yue-Ping Yuan and Akira Uesugi with photography. This work was supported
in part by Grants-in-Aid from the National Natural Science Foundation of China (39600045)
and the Ministry of Education, Sci-\r\nence, Sports and Culture of Japan (09480211,
08458245)."
article_processing_charge: No
article_type: original
author:
- first_name: Jin
full_name: Li, Jin
last_name: Li
- first_name: Yu
full_name: Ding, Yu
last_name: Ding
- first_name: Kang
full_name: Xiong, Kang
last_name: Xiong
- first_name: Ji
full_name: Li, Ji
last_name: Li
- first_name: Ryuichi
full_name: Shigemoto, Ryuichi
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Noboru
full_name: Mizuno, Noboru
last_name: Mizuno
citation:
ama: 'Li J, Ding Y, Xiong K, Li J, Shigemoto R, Mizuno N. Substance P receptor (NK1)-immunoreactive
neurons projecting to the periaqueductal gray: Distribution in the spinal trigeminal
nucleus and the spinal cord of the rat. Neuroscience Research. 1998;30(3):219-225.
doi:10.1016/S0168-0102(97)00132-6'
apa: 'Li, J., Ding, Y., Xiong, K., Li, J., Shigemoto, R., & Mizuno, N. (1998).
Substance P receptor (NK1)-immunoreactive neurons projecting to the periaqueductal
gray: Distribution in the spinal trigeminal nucleus and the spinal cord of the
rat. Neuroscience Research. Elsevier. https://doi.org/10.1016/S0168-0102(97)00132-6'
chicago: 'Li, Jin, Yu Ding, Kang Xiong, Ji Li, Ryuichi Shigemoto, and Noboru Mizuno.
“Substance P Receptor (NK1)-Immunoreactive Neurons Projecting to the Periaqueductal
Gray: Distribution in the Spinal Trigeminal Nucleus and the Spinal Cord of the
Rat.” Neuroscience Research. Elsevier, 1998. https://doi.org/10.1016/S0168-0102(97)00132-6.'
ieee: 'J. Li, Y. Ding, K. Xiong, J. Li, R. Shigemoto, and N. Mizuno, “Substance
P receptor (NK1)-immunoreactive neurons projecting to the periaqueductal gray:
Distribution in the spinal trigeminal nucleus and the spinal cord of the rat,”
Neuroscience Research, vol. 30, no. 3. Elsevier, pp. 219–225, 1998.'
ista: 'Li J, Ding Y, Xiong K, Li J, Shigemoto R, Mizuno N. 1998. Substance P receptor
(NK1)-immunoreactive neurons projecting to the periaqueductal gray: Distribution
in the spinal trigeminal nucleus and the spinal cord of the rat. Neuroscience
Research. 30(3), 219–225.'
mla: 'Li, Jin, et al. “Substance P Receptor (NK1)-Immunoreactive Neurons Projecting
to the Periaqueductal Gray: Distribution in the Spinal Trigeminal Nucleus and
the Spinal Cord of the Rat.” Neuroscience Research, vol. 30, no. 3, Elsevier,
1998, pp. 219–25, doi:10.1016/S0168-0102(97)00132-6.'
short: J. Li, Y. Ding, K. Xiong, J. Li, R. Shigemoto, N. Mizuno, Neuroscience Research
30 (1998) 219–225.
date_created: 2018-12-11T11:58:31Z
date_published: 1998-03-01T00:00:00Z
date_updated: 2022-09-01T12:19:44Z
day: '01'
doi: 10.1016/S0168-0102(97)00132-6
extern: '1'
external_id:
pmid:
- '9593332'
intvolume: ' 30'
issue: '3'
language:
- iso: eng
month: '03'
oa_version: None
page: 219 - 225
pmid: 1
publication: Neuroscience Research
publication_identifier:
issn:
- 0168-0102
publication_status: published
publisher: Elsevier
publist_id: '4315'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Substance P receptor (NK1)-immunoreactive neurons projecting to the periaqueductal
gray: Distribution in the spinal trigeminal nucleus and the spinal cord of the rat'
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 30
year: '1998'
...
---
_id: '2584'
abstract:
- lang: eng
text: The distributions of two alternative splicing variants of metabotropic glutamate
receptor mGluR7, mGluR7a and mGluR7b, were examined immunohistochemically in the
rat and mouse by using variant-specific antibodies raised against C-terminal portions
of rat mGluR7a and human mGluR7b. Many regions throughout the central nervous
system (CNS) showed mGluR7-like immunoreactivities (LI). The distribution patterns
of mGluR7-LI in the rat were substantially the same as those in the mouse, although
some species differences were observed in a few regions. Intense mGluR7a-LI was
seen in the main and accessory olfactory bulbs, anterior olfactory nucleus, islands
of Calleja, superficial layers of the olfactory tubercle, piriform cortex and
entorhinal cortex, periamygdaloid cortex, amygdalohippocampal area, hippocampus,
layer I of the neocortical regions, globus pallidus, superficial layers of the
superior colliculus, locus coeruleus, and superficial layers of the medullary
and spinal dorsal horns. The distribution of mGluR7b was more restricted. It was
intense in the islands of Calleja, substantia innominata, hippocampus, ventral
pallidum, and globus pallidus. The medial habenular nucleus also showed intense
mGluR7a-LI in the rat but not in the mouse. For both mGluR7a- and mGluR7b-LI,
localization in the active zones of presynaptic axon terminals was confirmed electron
microscopically at synapses of both the asymmetrical and symmetrical types. It
is noteworthy that mGluR7a-LI is seen preferentially in relay nuclei of the sensory
pathways and that both mGluR7a- and mGluR7b-LI are observed not only in presumed
glutamatergic axon terminals, but also in non-glutamatergic axon terminals including
presumed inhibitory ones. Thus, mGluR7 may play roles not only as an autoreceptor
in glutamatergic axon terminals, but also as a presynaptic heteroreceptor in non-glutamatergic
axon terminals in various CNS regions.
acknowledgement: The authors are grateful for photographic help of Mr.Akira
Uesugi, and the support of Dr. Kajitaro Morita inMorita Clinic of Internal Medicine
and Pediatrics, Kadoma,Osaka, Japan. The authors also express gratitude for thesupport of Dr. Satoru Fukuchi, Dr. Ritsu Hayashi, Dr.Sohzaburo Hayashi, Dr. Mizuho Katsurada, Dr. HitoshiKawai,
Dr. Yutaka Kitani, Dr. Toshihiko Kuroda, Dr. KeikoKumagai, Dr. Hiroshi Matsubara, Dr. Hiroshi Mat-sushima, Dr. Chisato Minakuchi, Dr. Gonpei Niwa, Dr.Hajime
Oda, Dr. Mashiko Ohbayashi, Dr. Sei-ichi Ohbaya-shi, Dr. Hiroyasu Ohtsuka, Dr. Shigeo
Tamaki, Dr. EizoWatanabe, Dr. Kazuo Yoshino, and Dr. Toshiaki Yoshino.
article_processing_charge: No
article_type: original
author:
- first_name: Ayae
full_name: Kinoshita, Ayae
last_name: Kinoshita
- first_name: Ryuichi
full_name: Shigemoto, Ryuichi
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Hitoshi
full_name: Ohishi, Hitoshi
last_name: Ohishi
- first_name: Herman
full_name: Van Der Putten, Herman
last_name: Van Der Putten
- first_name: Noboru
full_name: Mizuno, Noboru
last_name: Mizuno
citation:
ama: 'Kinoshita A, Shigemoto R, Ohishi H, Van Der Putten H, Mizuno N. Immunohistochemical
localization of metabotropic glutamate receptors, mGluR7a and mGluR7b, in the
central nervous system of the adult rat and mouse: A light and electron microscopic
study. Journal of Comparative Neurology. 1998;393(3):332-352. doi:10.1002/(SICI)1096-9861(19980413)393:3<332::AID-CNE6>3.0.CO;2-2'
apa: 'Kinoshita, A., Shigemoto, R., Ohishi, H., Van Der Putten, H., & Mizuno,
N. (1998). Immunohistochemical localization of metabotropic glutamate receptors,
mGluR7a and mGluR7b, in the central nervous system of the adult rat and mouse:
A light and electron microscopic study. Journal of Comparative Neurology.
Wiley-Blackwell. https://doi.org/10.1002/(SICI)1096-9861(19980413)393:3<332::AID-CNE6>3.0.CO;2-2'
chicago: 'Kinoshita, Ayae, Ryuichi Shigemoto, Hitoshi Ohishi, Herman Van Der Putten,
and Noboru Mizuno. “Immunohistochemical Localization of Metabotropic Glutamate
Receptors, MGluR7a and MGluR7b, in the Central Nervous System of the Adult Rat
and Mouse: A Light and Electron Microscopic Study.” Journal of Comparative
Neurology. Wiley-Blackwell, 1998. https://doi.org/10.1002/(SICI)1096-9861(19980413)393:3<332::AID-CNE6>3.0.CO;2-2.'
ieee: 'A. Kinoshita, R. Shigemoto, H. Ohishi, H. Van Der Putten, and N. Mizuno,
“Immunohistochemical localization of metabotropic glutamate receptors, mGluR7a
and mGluR7b, in the central nervous system of the adult rat and mouse: A light
and electron microscopic study,” Journal of Comparative Neurology, vol.
393, no. 3. Wiley-Blackwell, pp. 332–352, 1998.'
ista: 'Kinoshita A, Shigemoto R, Ohishi H, Van Der Putten H, Mizuno N. 1998. Immunohistochemical
localization of metabotropic glutamate receptors, mGluR7a and mGluR7b, in the
central nervous system of the adult rat and mouse: A light and electron microscopic
study. Journal of Comparative Neurology. 393(3), 332–352.'
mla: 'Kinoshita, Ayae, et al. “Immunohistochemical Localization of Metabotropic
Glutamate Receptors, MGluR7a and MGluR7b, in the Central Nervous System of the
Adult Rat and Mouse: A Light and Electron Microscopic Study.” Journal of Comparative
Neurology, vol. 393, no. 3, Wiley-Blackwell, 1998, pp. 332–52, doi:10.1002/(SICI)1096-9861(19980413)393:3<332::AID-CNE6>3.0.CO;2-2.'
short: A. Kinoshita, R. Shigemoto, H. Ohishi, H. Van Der Putten, N. Mizuno, Journal
of Comparative Neurology 393 (1998) 332–352.
date_created: 2018-12-11T11:58:31Z
date_published: 1998-03-13T00:00:00Z
date_updated: 2022-09-01T12:11:04Z
day: '13'
doi: 10.1002/(SICI)1096-9861(19980413)393:3<332::AID-CNE6>3.0.CO;2-2
extern: '1'
external_id:
pmid:
- '9548554'
intvolume: ' 393'
issue: '3'
language:
- iso: eng
month: '03'
oa_version: None
page: 332 - 352
pmid: 1
publication: Journal of Comparative Neurology
publication_identifier:
issn:
- 0021-9967
publication_status: published
publisher: Wiley-Blackwell
publist_id: '4314'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Immunohistochemical localization of metabotropic glutamate receptors, mGluR7a
and mGluR7b, in the central nervous system of the adult rat and mouse: A light and
electron microscopic study'
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 393
year: '1998'
...
---
_id: '2585'
abstract:
- lang: eng
text: Localization of metabetropic glutamate receptor subtypes, mGluR1, mGluRlu,
mGluR2/3, mGluR4a, mGluR5, mGluR7a, mGluR7b, and mGluR8, was examined in some
of the target areas of projection fibers from the main and accessory olfactory
bulbs (MOB and AOB) by using subtype-specific antibodies. The superficial layer
of the olfactory tubercle and layer Ia of the pitiform cortex, the target areas
of MOB, showed marked mGluR1-, mGluR5-, mGluR7a-, and mGluR8-like immunoreactivities
(-LI), and rather weak mGluR2/3-LI. The periamygdaloid cortical region including
the target areas of both MOB and AOB showed intense mGluR2/3-LI as well as marked
mGluRl-, mGluR5-, mGluR7a-, and mGluRS-LI. No significant mGluR1a-, mGluR4a-,
or mGluR7b-LI was seen in these regions. After transection of the lateral olfactory
tract, mGluR2/3-, mGluR7a-, and mGluR8-LI were reduced markedly in the target
regions on the side ipsilateral to the transection; no significant changes were
detected in mGluR1- or mGIuR5-LI. Double labeling experiments indicated light
and electron microscopically colocalization of mGluR7a- and mGluRS-LI in axon
terminals on dendritic shafts of presumed interneurons in the superficial layer
of the olfactory tubercle and layer Ia of the piriform cortex. Electron microscopically
mGluR2/3-LI was seen in preterminal and terminal portions of axons, whereas mGluR7a-
and mGluRS-LI were associated with presynaptic membrane specialization. Immunolabeled
axon terminals were filled with round synaptic vesicles and constituted asymmetric
synapses with dendritic profiles. The results suggest that glutamate release from
axon terminals of projection fibers from MOB and AOB is regulated presynaptically
and differentially through mGluR2/3, mGluR7a, and/or mGluRS.
acknowledgement: The authors are grateful for photographic help of Mr.Akira
Uesugi. The authors also express their gratitudesfor the support of Dr. Satoru Fukuchi,
Dr. Ritsu Hayashi,Dr. Sohzaburo Hayashi, Dr. Mizuho Katsurada, Dr. Hitoshi Kawai,
Dr. Yutaka Kitani, Dr. Toshihiko Kuroda, Dr.Keiko Kumagai, Dr. Hiroshi Matsubara,
Dr. Hiroshi Matsushima, Dr. Chisato Minakuchi, Dr. Gonpei Niwa, Dr.Hajime Oda,
Dr. Mashiko Ohbayashi, Dr. Seiichi Ohbayashi, Dr. Hiroyasu Ohtsuka, Dr. Shigeo Tamaki,
Dr. EizoWatanabe, Dr. Kazuo Yoshino, and Dr. Toshiaki Yoshino.
article_processing_charge: No
article_type: original
author:
- first_name: Eiki
full_name: Wada, Eiki
last_name: Wada
- first_name: Ryuichi
full_name: Shigemoto, Ryuichi
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Ayae
full_name: Kinoshita, Ayae
last_name: Kinoshita
- first_name: Hitoshi
full_name: Ohishi, Hitoshi
last_name: Ohishi
- first_name: Noboru
full_name: Mizuno, Noboru
last_name: Mizuno
citation:
ama: 'Wada E, Shigemoto R, Kinoshita A, Ohishi H, Mizuno N. Metabotropic glutamate
receptor subtypes in axon terminals of projection fibers from the main and accessory
olfactory bulbs: A light and electron microscopic immunohistochemical study in
the rat. Journal of Comparative Neurology. 1998;393(4):493-504. doi:10.1002/(SICI)1096-9861(19980420)393:4<493::AID-CNE8>3.0.CO;2-W'
apa: 'Wada, E., Shigemoto, R., Kinoshita, A., Ohishi, H., & Mizuno, N. (1998).
Metabotropic glutamate receptor subtypes in axon terminals of projection fibers
from the main and accessory olfactory bulbs: A light and electron microscopic
immunohistochemical study in the rat. Journal of Comparative Neurology.
Wiley-Blackwell. https://doi.org/10.1002/(SICI)1096-9861(19980420)393:4<493::AID-CNE8>3.0.CO;2-W'
chicago: 'Wada, Eiki, Ryuichi Shigemoto, Ayae Kinoshita, Hitoshi Ohishi, and Noboru
Mizuno. “Metabotropic Glutamate Receptor Subtypes in Axon Terminals of Projection
Fibers from the Main and Accessory Olfactory Bulbs: A Light and Electron Microscopic
Immunohistochemical Study in the Rat.” Journal of Comparative Neurology.
Wiley-Blackwell, 1998. https://doi.org/10.1002/(SICI)1096-9861(19980420)393:4<493::AID-CNE8>3.0.CO;2-W.'
ieee: 'E. Wada, R. Shigemoto, A. Kinoshita, H. Ohishi, and N. Mizuno, “Metabotropic
glutamate receptor subtypes in axon terminals of projection fibers from the main
and accessory olfactory bulbs: A light and electron microscopic immunohistochemical
study in the rat,” Journal of Comparative Neurology, vol. 393, no. 4. Wiley-Blackwell,
pp. 493–504, 1998.'
ista: 'Wada E, Shigemoto R, Kinoshita A, Ohishi H, Mizuno N. 1998. Metabotropic
glutamate receptor subtypes in axon terminals of projection fibers from the main
and accessory olfactory bulbs: A light and electron microscopic immunohistochemical
study in the rat. Journal of Comparative Neurology. 393(4), 493–504.'
mla: 'Wada, Eiki, et al. “Metabotropic Glutamate Receptor Subtypes in Axon Terminals
of Projection Fibers from the Main and Accessory Olfactory Bulbs: A Light and
Electron Microscopic Immunohistochemical Study in the Rat.” Journal of Comparative
Neurology, vol. 393, no. 4, Wiley-Blackwell, 1998, pp. 493–504, doi:10.1002/(SICI)1096-9861(19980420)393:4<493::AID-CNE8>3.0.CO;2-W.'
short: E. Wada, R. Shigemoto, A. Kinoshita, H. Ohishi, N. Mizuno, Journal of Comparative
Neurology 393 (1998) 493–504.
date_created: 2018-12-11T11:58:31Z
date_published: 1998-04-20T00:00:00Z
date_updated: 2022-08-31T14:53:58Z
day: '20'
doi: 10.1002/(SICI)1096-9861(19980420)393:4<493::AID-CNE8>3.0.CO;2-W
extern: '1'
external_id:
pmid:
- '9550154'
intvolume: ' 393'
issue: '4'
language:
- iso: eng
month: '04'
oa_version: None
page: 493 - 504
pmid: 1
publication: Journal of Comparative Neurology
publication_identifier:
issn:
- 0021-9967
publication_status: published
publisher: Wiley-Blackwell
publist_id: '4313'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Metabotropic glutamate receptor subtypes in axon terminals of projection fibers
from the main and accessory olfactory bulbs: A light and electron microscopic immunohistochemical
study in the rat'
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 393
year: '1998'
...
---
_id: '2586'
abstract:
- lang: eng
text: The role of inhibitory Golgi cells in cerebellar function was investigated
by selectively ablating Golgi cells expressing human interleukin-2 receptor α
subunit in transgenic mice, using the immunotoxin- mediated cell targeting technique.
Golgi cell disruption caused severe acute motor disorders. These mice showed gradual
recovery but retained a continuing inability to perform compound movements. Optical
and electrical recordings combined with immunocytological analysis indicated that
elimination of Golgi cells not only reduces GABA-mediated inhibition but also
attenuates functional NMDA receptors in granule cells. These results demonstrate
that synaptic integration involving both GABA inhibition and NMDA receptor activation
is essential for compound motor coordination. Furthermore, this integration can
adapt after Golgi cell elimination so as not to evoke overexcitation by the reduction
of NMDA receptors.
acknowledgement: "We thank Kumlesh K Dev for careful reading of this manuscript, Peter
Somogyi and Hirohide Sawada for invaluable advice, and Akira Uesugi for photographic
assistance. This work was supported in part by research grants from the Ministry
of Education, Science and Culture of Japan. the Sankyo Foundation. the Yamanouchi
Founda-tion. the Biomolecular Engineering Research Institute, CREST and the International
Resource Program of the National Cancer Institute. \r\n"
article_processing_charge: No
article_type: original
author:
- first_name: Dai
full_name: Watanabe, Dai
last_name: Watanabe
- first_name: Hitoshi
full_name: Inokawa, Hitoshi
last_name: Inokawa
- first_name: Kouichi
full_name: Hashimoto, Kouichi
last_name: Hashimoto
- first_name: Noboru
full_name: Suzuki, Noboru
last_name: Suzuki
- first_name: Masanobu
full_name: Kano, Masanobu
last_name: Kano
- first_name: Ryuichi
full_name: Shigemoto, Ryuichi
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Tomoo
full_name: Hirano, Tomoo
last_name: Hirano
- first_name: Keisuke
full_name: Toyama, Keisuke
last_name: Toyama
- first_name: Satoshi
full_name: Kaneko, Satoshi
last_name: Kaneko
- first_name: Mineto
full_name: Yokoi, Mineto
last_name: Yokoi
- first_name: Koki
full_name: Moriyoshi, Koki
last_name: Moriyoshi
- first_name: Misao
full_name: Suzuki, Misao
last_name: Suzuki
- first_name: Kazuto
full_name: Kobayashi, Kazuto
last_name: Kobayashi
- first_name: Toshiharu
full_name: Nagatsu, Toshiharu
last_name: Nagatsu
- first_name: Robert
full_name: Kreitman, Robert
last_name: Kreitman
- first_name: Ira
full_name: Pastan, Ira
last_name: Pastan
- first_name: Shigetada
full_name: Nakanishi, Shigetada
last_name: Nakanishi
citation:
ama: Watanabe D, Inokawa H, Hashimoto K, et al. Ablation of cerebellar Golgi cells
disrupts synaptic integration involving GABA inhibition and NMDA receptor activation
in motor coordination. Cell. 1998;95(1):17-27. doi:10.1016/S0092-8674(00)81779-1
apa: Watanabe, D., Inokawa, H., Hashimoto, K., Suzuki, N., Kano, M., Shigemoto,
R., … Nakanishi, S. (1998). Ablation of cerebellar Golgi cells disrupts synaptic
integration involving GABA inhibition and NMDA receptor activation in motor coordination.
Cell. Cell Press. https://doi.org/10.1016/S0092-8674(00)81779-1
chicago: Watanabe, Dai, Hitoshi Inokawa, Kouichi Hashimoto, Noboru Suzuki, Masanobu
Kano, Ryuichi Shigemoto, Tomoo Hirano, et al. “Ablation of Cerebellar Golgi Cells
Disrupts Synaptic Integration Involving GABA Inhibition and NMDA Receptor Activation
in Motor Coordination.” Cell. Cell Press, 1998. https://doi.org/10.1016/S0092-8674(00)81779-1.
ieee: D. Watanabe et al., “Ablation of cerebellar Golgi cells disrupts synaptic
integration involving GABA inhibition and NMDA receptor activation in motor coordination,”
Cell, vol. 95, no. 1. Cell Press, pp. 17–27, 1998.
ista: Watanabe D, Inokawa H, Hashimoto K, Suzuki N, Kano M, Shigemoto R, Hirano
T, Toyama K, Kaneko S, Yokoi M, Moriyoshi K, Suzuki M, Kobayashi K, Nagatsu T,
Kreitman R, Pastan I, Nakanishi S. 1998. Ablation of cerebellar Golgi cells disrupts
synaptic integration involving GABA inhibition and NMDA receptor activation in
motor coordination. Cell. 95(1), 17–27.
mla: Watanabe, Dai, et al. “Ablation of Cerebellar Golgi Cells Disrupts Synaptic
Integration Involving GABA Inhibition and NMDA Receptor Activation in Motor Coordination.”
Cell, vol. 95, no. 1, Cell Press, 1998, pp. 17–27, doi:10.1016/S0092-8674(00)81779-1.
short: D. Watanabe, H. Inokawa, K. Hashimoto, N. Suzuki, M. Kano, R. Shigemoto,
T. Hirano, K. Toyama, S. Kaneko, M. Yokoi, K. Moriyoshi, M. Suzuki, K. Kobayashi,
T. Nagatsu, R. Kreitman, I. Pastan, S. Nakanishi, Cell 95 (1998) 17–27.
date_created: 2018-12-11T11:58:32Z
date_published: 1998-10-02T00:00:00Z
date_updated: 2022-08-31T13:46:20Z
day: '02'
doi: 10.1016/S0092-8674(00)81779-1
extern: '1'
external_id:
pmid:
- '9778244 '
intvolume: ' 95'
issue: '1'
language:
- iso: eng
month: '10'
oa_version: None
page: 17 - 27
pmid: 1
publication: Cell
publication_identifier:
issn:
- 0092-8674
publication_status: published
publisher: Cell Press
publist_id: '4312'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Ablation of cerebellar Golgi cells disrupts synaptic integration involving
GABA inhibition and NMDA receptor activation in motor coordination
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 95
year: '1998'
...
---
_id: '2588'
abstract:
- lang: eng
text: "B-type receptors for the neurotransmitter GABA (γ-aminobutyric acid) inhibit
neuronal activity through G-protein-coupled second-messenger systems, which regulate
the release of neurotransmitters and the activity of ion channels and adenylyl
cyclase. Physiological and biochemical studies show that there are differences
in drug efficiencies at different GABA(B) receptors, so it is expected that GABA(B)-receptor
(GABA(B)R) subtypes exist. Two GABA(B)-receptor splice variants have been cloned
(GABA(B)R1a and GABA(B)R1b), but native GABA(B) receptors and recombinant receptors
showed unexplained differences in agonist-binding potencies. Moreover, the activation
of presumed effector ion channels in heterologous cells expressing the recombinant
receptors proved difficult. Here we describe a new GABA(B) receptor subtype, GABA(B)R2,
which does not bind available GABA(B) antagonists with measurable potency. GABA(B)R1a,
GABA(B)R1b and GABA(B)R2 alone do not activate Kir3-type potassium channels efficiently,
but co- expression of these receptors yields a robust coupling to activation of
Kir3 channels. We provide evidence for the assembly of heteromeric GABA(B) receptors
in vivo and show that GABA(B)R2 and GABA(B)R1a/b proteins immunoprecipitate and
localize together at dendritic spines. The heteromeric receptor complexes exhibit
a significant increase in agonist- and partial- agonist-binding potencies as compared
with individual receptors and probably represent the predominant native GABA(B)
receptor. Heteromeric assembly among G-protein-coupled receptors has not, to our
knowledge, been described before.\r\n"
acknowledgement: We thank D. Ristig, A. Begrich, I. Meigel and S. Leonhard for technical
assistance.
article_processing_charge: No
article_type: original
author:
- first_name: Klemens
full_name: Kaupmann, Klemens
last_name: Kaupmann
- first_name: Barbara
full_name: Malitschek, Barbara
last_name: Malitschek
- first_name: Valérie
full_name: Schuler, Valérie
last_name: Schuler
- first_name: Jacob
full_name: Heid, Jacob
last_name: Heid
- first_name: Wolfgang
full_name: Froestl, Wolfgang
last_name: Froestl
- first_name: Pascal
full_name: Beck, Pascal
last_name: Beck
- first_name: Johannes
full_name: Mosbacher, Johannes
last_name: Mosbacher
- first_name: Serge
full_name: Bischoff, Serge
last_name: Bischoff
- first_name: Ákos
full_name: Kulik, Ákos
last_name: Kulik
- first_name: Ryuichi
full_name: Shigemoto, Ryuichi
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Andreas
full_name: Karschin, Andreas
last_name: Karschin
- first_name: Bernhard
full_name: Bettler, Bernhard
last_name: Bettler
citation:
ama: Kaupmann K, Malitschek B, Schuler V, et al. GABA(B)-receptor subtypes assemble
into functional heteromeric complexes. Nature. 1998;396(6712):683-687.
doi:10.1038/25360
apa: Kaupmann, K., Malitschek, B., Schuler, V., Heid, J., Froestl, W., Beck, P.,
… Bettler, B. (1998). GABA(B)-receptor subtypes assemble into functional heteromeric
complexes. Nature. Nature Publishing Group. https://doi.org/10.1038/25360
chicago: Kaupmann, Klemens, Barbara Malitschek, Valérie Schuler, Jacob Heid, Wolfgang
Froestl, Pascal Beck, Johannes Mosbacher, et al. “ GABA(B)-Receptor Subtypes Assemble
into Functional Heteromeric Complexes.” Nature. Nature Publishing Group,
1998. https://doi.org/10.1038/25360.
ieee: K. Kaupmann et al., “ GABA(B)-receptor subtypes assemble into functional
heteromeric complexes,” Nature, vol. 396, no. 6712. Nature Publishing Group,
pp. 683–687, 1998.
ista: Kaupmann K, Malitschek B, Schuler V, Heid J, Froestl W, Beck P, Mosbacher
J, Bischoff S, Kulik Á, Shigemoto R, Karschin A, Bettler B. 1998. GABA(B)-receptor
subtypes assemble into functional heteromeric complexes. Nature. 396(6712), 683–687.
mla: Kaupmann, Klemens, et al. “ GABA(B)-Receptor Subtypes Assemble into Functional
Heteromeric Complexes.” Nature, vol. 396, no. 6712, Nature Publishing Group,
1998, pp. 683–87, doi:10.1038/25360.
short: K. Kaupmann, B. Malitschek, V. Schuler, J. Heid, W. Froestl, P. Beck, J.
Mosbacher, S. Bischoff, Á. Kulik, R. Shigemoto, A. Karschin, B. Bettler, Nature
396 (1998) 683–687.
date_created: 2018-12-11T11:58:32Z
date_published: 1998-12-17T00:00:00Z
date_updated: 2022-08-31T12:43:05Z
day: '17'
doi: 10.1038/25360
extern: '1'
external_id:
pmid:
- '9872317'
intvolume: ' 396'
issue: '6712'
language:
- iso: eng
month: '12'
oa_version: None
page: 683 - 687
pmid: 1
publication: Nature
publication_identifier:
issn:
- 0028-0836
publication_status: published
publisher: Nature Publishing Group
publist_id: '4309'
quality_controlled: '1'
scopus_import: '1'
status: public
title: ' GABA(B)-receptor subtypes assemble into functional heteromeric complexes'
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 396
year: '1998'
...
---
_id: '2589'
abstract:
- lang: eng
text: Immunoreactivity for the substance P receptor (NK1 receptor) has been investigated
by light and electron microscopy in the dorsal vagal complexes of adult rats and
cats. The general pattern of NK1 immunoreactivity was similar for both rat and
cat. Numerous NK1-immunoreactive neurons were present in the area postrema, the
nucleus of the solitary tract, and the dorsal motor nucleus of the vagus nerve.
The density of labelled neurons differed between the subnuclei of the nucleus
of the solitary tract. Overall, the efferent neurons of the dorsal motor nucleus
of the vagus nerve highly expressed NK1 when compared to neurons in the nucleus
of the solitary tract. The results are discussed with reference to the viscerotopic
organisation of the dorsal vagal complex. Ultrastructural analysis demonstrated
that NK1 immunoreactivity was present only at the membrane surface of somatic
and dendritic profiles of neurons. No labelling was found in axon terminals, axons,
or glial processes. NK1 immunoreactivity, as revealed by a preembedding immunogold
technique in serial ultrathin sections; was preferentially located at nonsynaptic
sites. A semiquantitative study suggested that the density of NK1 receptors is
statistically higher at membrane sites free of any contact (synaptic or not) with
axon terminals. The subcellular localisation of NK1 immunoreactivity was similar
for neurons of both rat and cat. These results suggest that in the dorsal vagal
complex, substance P might act on NK1 receptors through a process of volume transmission.
acknowledgement: The authors thank Dr. Wolfgang A.A. Kunze for his helpin the English
reviewing of the manuscript. The authorsthank Drs. Nadine Clerc, Jean-Pierre Kessler,
WolfgangA.A. Kunze, Jean-Jacques Puizillout, and Fabien Tell fortheir constructive
discussions and critiques of the manu-script. This study was supported by CNRS (FR45/UPR9024).
article_processing_charge: No
article_type: original
author:
- first_name: Agnès
full_name: Baude, Agnès
last_name: Baude
- first_name: Ryuichi
full_name: Shigemoto, Ryuichi
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
citation:
ama: 'Baude A, Shigemoto R. Cellular and subcellular distribution of substance P
receptor immunoreactivity in the dorsal vagal complex of the rat and cat: A light
and electron microscope study. Journal of Comparative Neurology. 1998;402(2):181-196.
doi:10.1002/(SICI)1096-9861(19981214)402:2<181::AID-CNE4>3.0.CO;2-B'
apa: 'Baude, A., & Shigemoto, R. (1998). Cellular and subcellular distribution
of substance P receptor immunoreactivity in the dorsal vagal complex of the rat
and cat: A light and electron microscope study. Journal of Comparative Neurology.
Wiley-Blackwell. https://doi.org/10.1002/(SICI)1096-9861(19981214)402:2<181::AID-CNE4>3.0.CO;2-B'
chicago: 'Baude, Agnès, and Ryuichi Shigemoto. “Cellular and Subcellular Distribution
of Substance P Receptor Immunoreactivity in the Dorsal Vagal Complex of the Rat
and Cat: A Light and Electron Microscope Study.” Journal of Comparative Neurology.
Wiley-Blackwell, 1998. https://doi.org/10.1002/(SICI)1096-9861(19981214)402:2<181::AID-CNE4>3.0.CO;2-B.'
ieee: 'A. Baude and R. Shigemoto, “Cellular and subcellular distribution of substance
P receptor immunoreactivity in the dorsal vagal complex of the rat and cat: A
light and electron microscope study,” Journal of Comparative Neurology,
vol. 402, no. 2. Wiley-Blackwell, pp. 181–196, 1998.'
ista: 'Baude A, Shigemoto R. 1998. Cellular and subcellular distribution of substance
P receptor immunoreactivity in the dorsal vagal complex of the rat and cat: A
light and electron microscope study. Journal of Comparative Neurology. 402(2),
181–196.'
mla: 'Baude, Agnès, and Ryuichi Shigemoto. “Cellular and Subcellular Distribution
of Substance P Receptor Immunoreactivity in the Dorsal Vagal Complex of the Rat
and Cat: A Light and Electron Microscope Study.” Journal of Comparative Neurology,
vol. 402, no. 2, Wiley-Blackwell, 1998, pp. 181–96, doi:10.1002/(SICI)1096-9861(19981214)402:2<181::AID-CNE4>3.0.CO;2-B.'
short: A. Baude, R. Shigemoto, Journal of Comparative Neurology 402 (1998) 181–196.
date_created: 2018-12-11T11:58:32Z
date_published: 1998-12-14T00:00:00Z
date_updated: 2022-08-31T12:57:30Z
day: '14'
doi: 10.1002/(SICI)1096-9861(19981214)402:2<181::AID-CNE4>3.0.CO;2-B
extern: '1'
external_id:
pmid:
- '9845242 '
intvolume: ' 402'
issue: '2'
language:
- iso: eng
month: '12'
oa_version: None
page: 181 - 196
pmid: 1
publication: Journal of Comparative Neurology
publication_identifier:
issn:
- 0021-9967
publication_status: published
publisher: Wiley-Blackwell
publist_id: '4310'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Cellular and subcellular distribution of substance P receptor immunoreactivity
in the dorsal vagal complex of the rat and cat: A light and electron microscope
study'
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 402
year: '1998'
...
---
_id: '2590'
abstract:
- lang: eng
text: Unipolar brush cells (UBCs) are a class of small neurons that are densely
concentrated in the granular layers of the vestibulocerebellar cortex and dorsal
cochlear nucleus. The UBCs form giant synapses with individual mossy fibre rosettes
on the dendrioles which make up their brush formations and are provided with numerous,
unusual non-synaptic appendages. In accord with the glutamatergic nature of mossy
fibres, our previous post-embedding immunocytochemical studies indicated that
various ionotropic glutamate receptor subunits are localized at the post-synaptic
densities of the giant synapses, whereas the non-synaptic appendages are immunonegative.
On the contrary, the metabotropic glutamate receptors mGluR1α and mGluR2/3 are
situated at the non-synaptic appendages and are lacking at the post-synaptic densities.
Other authors, however, have shown that antibodies to these metabotropic receptors
stain both appendages and post-synaptic densities. In the present study, we have
re-evaluated the distribution of metabotropic glutamate receptors in the UBCs
of the cerebellum and the cochlear nuclear complex by light and electron microscopic
pre-embedding immunocytochemistry with subtype-specific antibodies. We confirm
that UBCs dendritic brushes are densely immunostained by antibody to mGluR1α particularly
in the cerebellum and that antibody to mGluR2/3 labels at least a percentage of
the UBC brushes in both the cerebellum and cochlear nuclei. At the ultrastructural
level, it appears that mGluR1α and mGluR2/3 immunoreactivities are not associated
with the post-synaptic densities of the giant mossy fibre-UBC synapses, but instead
are concentrated on the non-synaptic appendages of the cerebellar UBCs. The non-synaptic
appendages, therefore, may be an important avenue for regulating the excitability
of UBCs and mediating glutamate effects on their still unknown intracellular signal
transduction cascades. We also show that the pre-synaptic densities of UBC dendrodendritic
junctions are mGluR2/3 positive. As previously demonstrated, antibodies to mGluR1α
and mGluR2/3 label subsets of Golgi cells. Antibody to mGluR5 does not stain UBCs
in the cerebellum and cochlear nucleus and reveals the somatodendritic compartment
of Golgi cells situated in the core of the cerebellar granular layer, whilst cochlear
nucleus Golgi cells are mGluR5 negative.
acknowledgement: The authors wish to thank Dr R. L. Huganir and coworkers for kindly
providing an aliquot of their mGluR1a antibody and Dr N. Traverse Slater for helpful
comments on the manuscript. The study was supported by US-PHS grants NS 09904 and
DC 01805 (to E.M.).
article_processing_charge: No
article_type: original
author:
- first_name: Dick
full_name: Jaarsma, Dick
last_name: Jaarsma
- first_name: Maria
full_name: Diño, Maria
last_name: Diño
- first_name: Hitoshi
full_name: Ohishi, Hitoshi
last_name: Ohishi
- first_name: Ryuichi
full_name: Shigemoto, Ryuichi
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Enrico
full_name: Mugnaini, Enrico
last_name: Mugnaini
citation:
ama: Jaarsma D, Diño M, Ohishi H, Shigemoto R, Mugnaini E. Metabotropic glutamate
receptors are associated with non-synaptic appendages of unipolar brush cells
in rat cerebellar cortex and cochlear nuclear complex. Journal of Neurocytology.
1998;27(5):303-327. doi:10.1023/A:1006982023657
apa: Jaarsma, D., Diño, M., Ohishi, H., Shigemoto, R., & Mugnaini, E. (1998). Metabotropic
glutamate receptors are associated with non-synaptic appendages of unipolar brush
cells in rat cerebellar cortex and cochlear nuclear complex. Journal of Neurocytology.
Kluwer. https://doi.org/10.1023/A:1006982023657
chicago: Jaarsma, Dick, Maria Diño, Hitoshi Ohishi, Ryuichi Shigemoto, and Enrico
Mugnaini. “ Metabotropic Glutamate Receptors Are Associated with Non-Synaptic
Appendages of Unipolar Brush Cells in Rat Cerebellar Cortex and Cochlear Nuclear
Complex.” Journal of Neurocytology. Kluwer, 1998. https://doi.org/10.1023/A:1006982023657.
ieee: D. Jaarsma, M. Diño, H. Ohishi, R. Shigemoto, and E. Mugnaini, “ Metabotropic
glutamate receptors are associated with non-synaptic appendages of unipolar brush
cells in rat cerebellar cortex and cochlear nuclear complex,” Journal of Neurocytology,
vol. 27, no. 5. Kluwer, pp. 303–327, 1998.
ista: Jaarsma D, Diño M, Ohishi H, Shigemoto R, Mugnaini E. 1998. Metabotropic
glutamate receptors are associated with non-synaptic appendages of unipolar brush
cells in rat cerebellar cortex and cochlear nuclear complex. Journal of Neurocytology.
27(5), 303–327.
mla: Jaarsma, Dick, et al. “ Metabotropic Glutamate Receptors Are Associated with
Non-Synaptic Appendages of Unipolar Brush Cells in Rat Cerebellar Cortex and Cochlear
Nuclear Complex.” Journal of Neurocytology, vol. 27, no. 5, Kluwer, 1998,
pp. 303–27, doi:10.1023/A:1006982023657.
short: D. Jaarsma, M. Diño, H. Ohishi, R. Shigemoto, E. Mugnaini, Journal of Neurocytology
27 (1998) 303–327.
date_created: 2018-12-11T11:58:33Z
date_published: 1998-01-01T00:00:00Z
date_updated: 2022-08-31T12:30:14Z
day: '01'
doi: 10.1023/A:1006982023657
extern: '1'
external_id:
pmid:
- '9923978 '
intvolume: ' 27'
issue: '5'
language:
- iso: eng
month: '01'
oa_version: None
page: 303 - 327
pmid: 1
publication: Journal of Neurocytology
publication_identifier:
issn:
- 0300-4864
publication_status: published
publisher: Kluwer
publist_id: '4308'
quality_controlled: '1'
scopus_import: '1'
status: public
title: ' Metabotropic glutamate receptors are associated with non-synaptic appendages
of unipolar brush cells in rat cerebellar cortex and cochlear nuclear complex'
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 27
year: '1998'
...
---
_id: '2695'
abstract:
- lang: eng
text: 'We study a quantum particle in a random potential in two scaling limits:
the low density limit (or Boltzman-Grad) and the weak coupling limit. The low
density limit is the quantum analogue of the Lorentz gas. In both cases, the phase
space density of the quantum evolution defined through the Wigner transform or
the Husimi function converges weakly to a linear Boltz-mann equation with collision
kernel given by the quantum scattering cross section. '
alternative_title:
- Contemporary Mathematics
article_processing_charge: No
author:
- first_name: László
full_name: Erdös, László
id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
last_name: Erdös
orcid: 0000-0001-5366-9603
- first_name: Horng
full_name: Yau, Horng
last_name: Yau
citation:
ama: 'Erdös L, Yau H. Linear Boltzmann equation as scaling limit of quantum Lorentz
gas. In: Advances in Differential Equations and Mathematical Physics. Vol
217. American Mathematical Society; 1998:137-155. doi:10.1090/conm/217'
apa: Erdös, L., & Yau, H. (1998). Linear Boltzmann equation as scaling limit
of quantum Lorentz gas. In Advances in Differential Equations and Mathematical
Physics (Vol. 217, pp. 137–155). American Mathematical Society. https://doi.org/10.1090/conm/217
chicago: Erdös, László, and Horng Yau. “Linear Boltzmann Equation as Scaling Limit
of Quantum Lorentz Gas.” In Advances in Differential Equations and Mathematical
Physics, 217:137–55. American Mathematical Society, 1998. https://doi.org/10.1090/conm/217.
ieee: L. Erdös and H. Yau, “Linear Boltzmann equation as scaling limit of quantum
Lorentz gas,” in Advances in Differential Equations and Mathematical Physics,
vol. 217, American Mathematical Society, 1998, pp. 137–155.
ista: 'Erdös L, Yau H. 1998.Linear Boltzmann equation as scaling limit of quantum
Lorentz gas. In: Advances in Differential Equations and Mathematical Physics.
Contemporary Mathematics, vol. 217, 137–155.'
mla: Erdös, László, and Horng Yau. “Linear Boltzmann Equation as Scaling Limit of
Quantum Lorentz Gas.” Advances in Differential Equations and Mathematical Physics,
vol. 217, American Mathematical Society, 1998, pp. 137–55, doi:10.1090/conm/217.
short: L. Erdös, H. Yau, in:, Advances in Differential Equations and Mathematical
Physics, American Mathematical Society, 1998, pp. 137–155.
date_created: 2018-12-11T11:59:07Z
date_published: 1998-01-01T00:00:00Z
date_updated: 2022-08-31T11:46:40Z
day: '01'
doi: 10.1090/conm/217
extern: '1'
intvolume: ' 217'
language:
- iso: eng
month: '01'
oa_version: None
page: 137 - 155
publication: Advances in Differential Equations and Mathematical Physics
publication_identifier:
issn:
- 0271-4132
publication_status: published
publisher: American Mathematical Society
publist_id: '4202'
quality_controlled: '1'
status: public
title: Linear Boltzmann equation as scaling limit of quantum Lorentz gas
type: book_chapter
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 217
year: '1998'
...
---
_id: '2728'
abstract:
- lang: eng
text: We obtain the Lifschitz tail, i.e. the exact low energy asymptotics of the
integrated density of states (IDS) of the two-dimensional magnetic Schrödinger
operator with a uniform magnetic field and random Poissonian impurities. The single
site potential is repulsive and it has a finite but nonzero range. We show that
the IDS is a continuous function of the energy at the bottom of the spectrum.
This result complements the earlier (nonrigorous) calculations by Brézin, Gross
and Itzykson which predict that the IDS is discontinuous at the bottom of the
spectrum for zero range (Dirac delta) impurities at low density. We also elucidate
the reason behind this apparent controversy. Our methods involve magnetic localization
techniques (both in space and energy) in addition to a modified version of the
"enlargement of obstacles" method developed by A.-S. Sznitman.
acknowledgement: The author is grateful to Professor A.-S. Sznitman for explaining
him his work and for fruitful discussions, and to the referee for pointing out errors
and for many helpful comments.This work has been initiated and later on completed
at the Forschungsinstitut für Mathematik, ETH Zürich.
article_processing_charge: No
article_type: original
author:
- first_name: László
full_name: Erdös, László
id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
last_name: Erdös
orcid: 0000-0001-5366-9603
citation:
ama: 'Erdös L. Lifschitz tail in a magnetic field: The nonclassical regime. Probability
Theory and Related Fields. 1998;112(3):321-371. doi:10.1007/s004400050193'
apa: 'Erdös, L. (1998). Lifschitz tail in a magnetic field: The nonclassical regime.
Probability Theory and Related Fields. Springer. https://doi.org/10.1007/s004400050193'
chicago: 'Erdös, László. “Lifschitz Tail in a Magnetic Field: The Nonclassical Regime.”
Probability Theory and Related Fields. Springer, 1998. https://doi.org/10.1007/s004400050193.'
ieee: 'L. Erdös, “Lifschitz tail in a magnetic field: The nonclassical regime,”
Probability Theory and Related Fields, vol. 112, no. 3. Springer, pp. 321–371,
1998.'
ista: 'Erdös L. 1998. Lifschitz tail in a magnetic field: The nonclassical regime.
Probability Theory and Related Fields. 112(3), 321–371.'
mla: 'Erdös, László. “Lifschitz Tail in a Magnetic Field: The Nonclassical Regime.”
Probability Theory and Related Fields, vol. 112, no. 3, Springer, 1998,
pp. 321–71, doi:10.1007/s004400050193.'
short: L. Erdös, Probability Theory and Related Fields 112 (1998) 321–371.
date_created: 2018-12-11T11:59:17Z
date_published: 1998-11-01T00:00:00Z
date_updated: 2022-08-30T08:17:54Z
day: '01'
doi: 10.1007/s004400050193
extern: '1'
intvolume: ' 112'
issue: '3'
language:
- iso: eng
month: '11'
oa_version: None
page: 321 - 371
publication: Probability Theory and Related Fields
publication_identifier:
issn:
- 0044-3719
publication_status: published
publisher: Springer
publist_id: '4163'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Lifschitz tail in a magnetic field: The nonclassical regime'
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 112
year: '1998'
...
---
_id: '3487'
abstract:
- lang: eng
text: It is widely accepted that individual neurons in the central nervous system
release only a single fast transmitter. The possibility of corelease of fast neurotransmitters
was examined by making paired recordings from synaptically connected neurons in
spinal cord slices. Unitary inhibitory postsynaptic currents generated at interneuron-motoneuron
synapses consisted of a strychnine-sensitive, glycine receptor-mediated component
and a bicuculline-sensitive, γ-aminobutyric acid (GABA)(A) receptor-mediated component.
These results indicate that spinal interneurons release both glycine and GABA
to activate functionally distinct receptors in their postsynaptic target cells.
A subset of miniature synaptic currents also showed both components, consistent
with corelease from individual synaptic vesicles.
acknowledgement: "See comment by Nicoll RA, Malenka RC (1998) Science 281:360-361\r\n"
article_processing_charge: No
article_type: original
author:
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
- first_name: Joseph
full_name: Bischofberger, Joseph
last_name: Bischofberger
- first_name: Jürgen
full_name: Sandkühler, Jürgen
last_name: Sandkühler
citation:
ama: Jonas PM, Bischofberger J, Sandkühler J. Corelease of two fast neurotransmitters
at a central synapse. Science. 1998;281(5375):419-424. doi:10.1126/science.281.5375.419
apa: Jonas, P. M., Bischofberger, J., & Sandkühler, J. (1998). Corelease of
two fast neurotransmitters at a central synapse. Science. American Association
for the Advancement of Science. https://doi.org/10.1126/science.281.5375.419
chicago: Jonas, Peter M, Joseph Bischofberger, and Jürgen Sandkühler. “Corelease
of Two Fast Neurotransmitters at a Central Synapse.” Science. American
Association for the Advancement of Science, 1998. https://doi.org/10.1126/science.281.5375.419.
ieee: P. M. Jonas, J. Bischofberger, and J. Sandkühler, “Corelease of two fast neurotransmitters
at a central synapse,” Science, vol. 281, no. 5375. American Association
for the Advancement of Science, pp. 419–424, 1998.
ista: Jonas PM, Bischofberger J, Sandkühler J. 1998. Corelease of two fast neurotransmitters
at a central synapse. Science. 281(5375), 419–424.
mla: Jonas, Peter M., et al. “Corelease of Two Fast Neurotransmitters at a Central
Synapse.” Science, vol. 281, no. 5375, American Association for the Advancement
of Science, 1998, pp. 419–24, doi:10.1126/science.281.5375.419.
short: P.M. Jonas, J. Bischofberger, J. Sandkühler, Science 281 (1998) 419–424.
date_created: 2018-12-11T12:03:35Z
date_published: 1998-07-17T00:00:00Z
date_updated: 2022-08-29T14:52:38Z
day: '17'
doi: 10.1126/science.281.5375.419
extern: '1'
external_id:
pmid:
- '9665886 '
intvolume: ' 281'
issue: '5375'
language:
- iso: eng
month: '07'
oa_version: None
page: 419 - 424
pmid: 1
publication: Science
publication_identifier:
issn:
- 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science
publist_id: '2900'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Corelease of two fast neurotransmitters at a central synapse
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 281
year: '1998'
...
---
_id: '3488'
abstract:
- lang: eng
text: We have examined gating and pharmacological characteristics of somatic K+
channels in fast-spiking interneurons and regularly spiking principal neurons
of hippocampal slices. In nucleated patches isolated from basket cells of the
dentate gyrus, a fast delayed rectifier K+ current component that was highly sensitive
to tetraethylammonium (TEA) and 4-aminopyridine (4- AP) (half-maximal inhibitory
concentrations <0.1 mM) predominated, contributing an average of 58% to the
total K+ current in these cells. By contrast, in pyramidal neurons of the CA1
region a rapidly inactivating A- type K+ current component that was TEA-resistant
prevailed, contributing 61% to the total K+ current. Both types of neurons also
showed small amounts of the K+ current component mainly found in the other type
of neuron and, in addition, a slow delayed rectifier K+ current component with
intermediate properties (sow inactivation, intermediate sensitivity to TEA). Single-cell
RT-PCR analysis of mRNA revealed that Kv3 (Kv3.1, Kv3.2) subunit transcripts were
expressed in almost all (89%) of the interneurons but only in 17% of the pyramidal
neurons. In contrast, Kv4 (Kv4.2, Kv4.3) subunit mRNAs were present in 87% of
pyramidal neurons but only in 55% of interneurons. Selective block of fast delayed
rectifier K+ channels, presumably assembled from Kv3 subunits, by 4-AP reduced
substantially the action potential frequency in interneurons. These results indicate
that the differential expression of Kv3 and Kv4 subunits shapes the action potential
phenotypes of principal neurons and interneurons in the cortex.
acknowledgement: Supported by German Israeli Foundation Grant I 0352–073.01/94 to
P.J. and Deutsche Forschungsgemeinschaft Grant Mo 432/3–1 to H.M. We thank Drs.
L. Y. Jan, D. McKinnon, O. Pongs, L. Salkoff, S. H. Snyder, and J. S. Trimmer for
providing plasmids, Dr. D. J. Surmeier for sharing unpublished data, and Drs. J.
Bischofberger and J. R. P. Geiger for critically reading this manuscript. M.M. and
J.H.S. contributed equally to this work.
article_processing_charge: No
article_type: original
author:
- first_name: Marco
full_name: Martina, Marco
last_name: Martina
- first_name: Jobst
full_name: Schultz, Jobst
last_name: Schultz
- first_name: Heimo
full_name: Ehmke, Heimo
last_name: Ehmke
- first_name: Hannah
full_name: Monyer, Hannah
last_name: Monyer
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
citation:
ama: Martina M, Schultz J, Ehmke H, Monyer H, Jonas PM. Functional and molecular
differences between voltage-gated K+ channels of fast-spiking interneurons and
pyramidal neurons of rat hippocampus. Journal of Neuroscience. 1998;18(20):8111-8125.
doi:10.1523/JNEUROSCI.18-20-08111.1998
apa: Martina, M., Schultz, J., Ehmke, H., Monyer, H., & Jonas, P. M. (1998).
Functional and molecular differences between voltage-gated K+ channels of fast-spiking
interneurons and pyramidal neurons of rat hippocampus. Journal of Neuroscience.
Society for Neuroscience. https://doi.org/10.1523/JNEUROSCI.18-20-08111.1998
chicago: Martina, Marco, Jobst Schultz, Heimo Ehmke, Hannah Monyer, and Peter M
Jonas. “Functional and Molecular Differences between Voltage-Gated K+ Channels
of Fast-Spiking Interneurons and Pyramidal Neurons of Rat Hippocampus.” Journal
of Neuroscience. Society for Neuroscience, 1998. https://doi.org/10.1523/JNEUROSCI.18-20-08111.1998.
ieee: M. Martina, J. Schultz, H. Ehmke, H. Monyer, and P. M. Jonas, “Functional
and molecular differences between voltage-gated K+ channels of fast-spiking interneurons
and pyramidal neurons of rat hippocampus,” Journal of Neuroscience, vol.
18, no. 20. Society for Neuroscience, pp. 8111–8125, 1998.
ista: Martina M, Schultz J, Ehmke H, Monyer H, Jonas PM. 1998. Functional and molecular
differences between voltage-gated K+ channels of fast-spiking interneurons and
pyramidal neurons of rat hippocampus. Journal of Neuroscience. 18(20), 8111–8125.
mla: Martina, Marco, et al. “Functional and Molecular Differences between Voltage-Gated
K+ Channels of Fast-Spiking Interneurons and Pyramidal Neurons of Rat Hippocampus.”
Journal of Neuroscience, vol. 18, no. 20, Society for Neuroscience, 1998,
pp. 8111–25, doi:10.1523/JNEUROSCI.18-20-08111.1998.
short: M. Martina, J. Schultz, H. Ehmke, H. Monyer, P.M. Jonas, Journal of Neuroscience
18 (1998) 8111–8125.
date_created: 2018-12-11T12:03:35Z
date_published: 1998-10-15T00:00:00Z
date_updated: 2022-08-29T14:20:39Z
day: '15'
doi: 10.1523/JNEUROSCI.18-20-08111.1998
extern: '1'
external_id:
pmid:
- '9763458'
intvolume: ' 18'
issue: '20'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6792860/
month: '10'
oa: 1
oa_version: None
page: 8111 - 8125
pmid: 1
publication: Journal of Neuroscience
publication_identifier:
issn:
- 0270-6474
publication_status: published
publisher: Society for Neuroscience
publist_id: '2899'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Functional and molecular differences between voltage-gated K+ channels of fast-spiking
interneurons and pyramidal neurons of rat hippocampus
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 18
year: '1998'
...
---
_id: '3506'
abstract:
- lang: eng
text: A method of geometric morphing between a first object having a first shape
and a second object having a second shape. The method includes the steps of generating
a first Delaunay complex corresponding to the first shape and a second Delaunay
complex corresponding to the second shape and generating a plurality of intermediary
Delaunay complexes defined by a continuous family of mixed shapes corresponding
to a mixing of the first shape and the second shape. The method further includes
the steps of constructing a first skin corresponding to the first Delaunay complex
and a second skin corresponding to the second Delaunay complex and constructing
a plurality of intermediary skins corresponding to the plurality of intermediary
Delaunay complexes. The first skin, second skin and plurality of intermediary
skins may be visually displayed on an output device.
applicant:
- Raindrop Geomagic, Inc.
article_processing_charge: No
author:
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
- first_name: Ping
full_name: Fu, Ping
last_name: Fu
citation:
ama: Edelsbrunner H, Fu P. Apparatus and method for geometric morphing. 1998.
apa: Edelsbrunner, H., & Fu, P. (1998). Apparatus and method for geometric morphing.
chicago: Edelsbrunner, Herbert, and Ping Fu. “Apparatus and Method for Geometric
Morphing,” 1998.
ieee: H. Edelsbrunner and P. Fu, “Apparatus and method for geometric morphing.”
1998.
ista: Edelsbrunner H, Fu P. 1998. Apparatus and method for geometric morphing.
mla: Edelsbrunner, Herbert, and Ping Fu. Apparatus and Method for Geometric Morphing.
1998.
short: H. Edelsbrunner, P. Fu, (1998).
date_created: 2018-12-11T12:03:41Z
date_published: 1998-12-15T00:00:00Z
date_updated: 2022-01-05T15:16:35Z
day: '15'
extern: '1'
ipc: G06T13/20 ; G06T2210/44
ipn: US5850229A
main_file_link:
- open_access: '1'
url: https://patents.google.com/patent/US5850229A
month: '12'
oa: 1
oa_version: Published Version
publication_date: 1998-12-15
publist_id: '2881'
status: public
title: Apparatus and method for geometric morphing
type: patent
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '1998'
...
---
_id: '3521'
abstract:
- lang: eng
text: Spike transmission probability between pyramidal cells and interneurons in
the CA1 pyramidal layer was investigated in the behaving rat by the simultaneous
recording of neuronal ensembles. Population synchrony was strongest during sharp
wave (SPW) bursts. However, the increase was three times larger for pyramidal
cells than for interneurons. The contribution of single pyramidal cells to the
discharge of interneurons was often large (up to 0.6 probability), as assessed
by the presence of significant (<3 ms) peaks in the cross-correlogram. Complex-spike
bursts were more effective than single spikes. Single cell contribution was higher
between SPW bursts than during SPWs or theta activity. Hence, single pyramidal
cells can reliably discharge interneurons, and the probability of spike transmission
is behavior dependent.
acknowledgement: We thank C. King, R. Miles, M. Recce, and the anonymous reviewers
for their constructive comments on the manuscript. This work was supported by the
National Institutes of Health (NS34994, MH54671 1P41RR09754), the Human Frontier
Science Program, and the Whitehall Foundation.
article_processing_charge: No
article_type: original
author:
- first_name: Jozsef L
full_name: Csicsvari, Jozsef L
id: 3FA14672-F248-11E8-B48F-1D18A9856A87
last_name: Csicsvari
orcid: 0000-0002-5193-4036
- first_name: Hajima
full_name: Hirase, Hajima
last_name: Hirase
- first_name: András
full_name: Czurkó, András
last_name: Czurkó
- first_name: György
full_name: Buzsáki, György
last_name: Buzsáki
citation:
ama: 'Csicsvari JL, Hirase H, Czurkó A, Buzsáki G. Reliability and state dependence
of pyramidal cell-interneuron synapses in the hippocampus: an ensemble approach
in the behaving rat. Neuron. 1998;21(1):179-189. doi:10.1016/S0896-6273(00)80525-5'
apa: 'Csicsvari, J. L., Hirase, H., Czurkó, A., & Buzsáki, G. (1998). Reliability
and state dependence of pyramidal cell-interneuron synapses in the hippocampus:
an ensemble approach in the behaving rat. Neuron. Elsevier. https://doi.org/10.1016/S0896-6273(00)80525-5'
chicago: 'Csicsvari, Jozsef L, Hajima Hirase, András Czurkó, and György Buzsáki.
“Reliability and State Dependence of Pyramidal Cell-Interneuron Synapses in the
Hippocampus: An Ensemble Approach in the Behaving Rat.” Neuron. Elsevier,
1998. https://doi.org/10.1016/S0896-6273(00)80525-5.'
ieee: 'J. L. Csicsvari, H. Hirase, A. Czurkó, and G. Buzsáki, “Reliability and state
dependence of pyramidal cell-interneuron synapses in the hippocampus: an ensemble
approach in the behaving rat,” Neuron, vol. 21, no. 1. Elsevier, pp. 179–189,
1998.'
ista: 'Csicsvari JL, Hirase H, Czurkó A, Buzsáki G. 1998. Reliability and state
dependence of pyramidal cell-interneuron synapses in the hippocampus: an ensemble
approach in the behaving rat. Neuron. 21(1), 179–189.'
mla: 'Csicsvari, Jozsef L., et al. “Reliability and State Dependence of Pyramidal
Cell-Interneuron Synapses in the Hippocampus: An Ensemble Approach in the Behaving
Rat.” Neuron, vol. 21, no. 1, Elsevier, 1998, pp. 179–89, doi:10.1016/S0896-6273(00)80525-5.'
short: J.L. Csicsvari, H. Hirase, A. Czurkó, G. Buzsáki, Neuron 21 (1998) 179–189.
date_created: 2018-12-11T12:03:46Z
date_published: 1998-07-01T00:00:00Z
date_updated: 2022-08-29T14:03:55Z
day: '01'
doi: 10.1016/S0896-6273(00)80525-5
extern: '1'
external_id:
pmid:
- '9697862 '
intvolume: ' 21'
issue: '1'
language:
- iso: eng
month: '07'
oa_version: None
page: 179 - 189
pmid: 1
publication: Neuron
publication_identifier:
issn:
- 0896-6273
publication_status: published
publisher: Elsevier
publist_id: '2865'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Reliability and state dependence of pyramidal cell-interneuron synapses in
the hippocampus: an ensemble approach in the behaving rat'
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 21
year: '1998'
...
---
_id: '3525'
author:
- first_name: Zoltán
full_name: Nádasdy, Zoltán
last_name: Nádasdy
- first_name: Jozsef L
full_name: Jozsef Csicsvari
id: 3FA14672-F248-11E8-B48F-1D18A9856A87
last_name: Csicsvari
orcid: 0000-0002-5193-4036
- first_name: Hajima
full_name: Hirase, Hajima
last_name: Hirase
- first_name: András
full_name: Czurkó, András
last_name: Czurkó
- first_name: György
full_name: Buzsáki, György
last_name: Buzsáki
citation:
ama: Nádasdy Z, Csicsvari JL, Hirase H, Czurkó A, Buzsáki G. Persistence and temporal
compression of spike sequences during fast field oscillation in the hippocampus.
European Journal of Neuroscience. 1998;10(Suppl. 10):9409-9409.
apa: Nádasdy, Z., Csicsvari, J. L., Hirase, H., Czurkó, A., & Buzsáki, G. (1998).
Persistence and temporal compression of spike sequences during fast field oscillation
in the hippocampus. European Journal of Neuroscience. Wiley-Blackwell.
chicago: Nádasdy, Zoltán, Jozsef L Csicsvari, Hajima Hirase, András Czurkó, and
György Buzsáki. “Persistence and Temporal Compression of Spike Sequences during
Fast Field Oscillation in the Hippocampus.” European Journal of Neuroscience.
Wiley-Blackwell, 1998.
ieee: Z. Nádasdy, J. L. Csicsvari, H. Hirase, A. Czurkó, and G. Buzsáki, “Persistence
and temporal compression of spike sequences during fast field oscillation in the
hippocampus,” European Journal of Neuroscience, vol. 10, no. Suppl. 10.
Wiley-Blackwell, pp. 9409–9409, 1998.
ista: Nádasdy Z, Csicsvari JL, Hirase H, Czurkó A, Buzsáki G. 1998. Persistence
and temporal compression of spike sequences during fast field oscillation in the
hippocampus. European Journal of Neuroscience. 10(Suppl. 10), 9409–9409.
mla: Nádasdy, Zoltán, et al. “Persistence and Temporal Compression of Spike Sequences
during Fast Field Oscillation in the Hippocampus.” European Journal of Neuroscience,
vol. 10, no. Suppl. 10, Wiley-Blackwell, 1998, pp. 9409–9409.
short: Z. Nádasdy, J.L. Csicsvari, H. Hirase, A. Czurkó, G. Buzsáki, European Journal
of Neuroscience 10 (1998) 9409–9409.
date_created: 2018-12-11T12:03:47Z
date_published: 1998-06-01T00:00:00Z
date_updated: 2021-01-12T07:44:04Z
day: '01'
extern: 1
intvolume: ' 10'
issue: Suppl. 10
month: '06'
page: 9409 - 9409
publication: European Journal of Neuroscience
publication_status: published
publisher: Wiley-Blackwell
publist_id: '2861'
quality_controlled: 0
status: public
title: Persistence and temporal compression of spike sequences during fast field oscillation
in the hippocampus
type: journal_article
volume: 10
year: '1998'
...
---
_id: '3527'
author:
- first_name: Jozsef L
full_name: Jozsef Csicsvari
id: 3FA14672-F248-11E8-B48F-1D18A9856A87
last_name: Csicsvari
orcid: 0000-0002-5193-4036
- first_name: András
full_name: Czurkó, András
last_name: Czurkó
- first_name: Hajima
full_name: Hirase, Hajima
last_name: Hirase
- first_name: György
full_name: Buzsáki, György
last_name: Buzsáki
citation:
ama: Csicsvari JL, Czurkó A, Hirase H, Buzsáki G. Monosynaptic interactions between
CA1 Pyramidal cells and interneuron in the behaving rat. European Journal of
Neuroscience. 1998;10(Suppl. 10):2553-2553.
apa: Csicsvari, J. L., Czurkó, A., Hirase, H., & Buzsáki, G. (1998). Monosynaptic
interactions between CA1 Pyramidal cells and interneuron in the behaving rat.
European Journal of Neuroscience. Wiley-Blackwell.
chicago: Csicsvari, Jozsef L, András Czurkó, Hajima Hirase, and György Buzsáki.
“Monosynaptic Interactions between CA1 Pyramidal Cells and Interneuron in the
Behaving Rat.” European Journal of Neuroscience. Wiley-Blackwell, 1998.
ieee: J. L. Csicsvari, A. Czurkó, H. Hirase, and G. Buzsáki, “Monosynaptic interactions
between CA1 Pyramidal cells and interneuron in the behaving rat,” European
Journal of Neuroscience, vol. 10, no. Suppl. 10. Wiley-Blackwell, pp. 2553–2553,
1998.
ista: Csicsvari JL, Czurkó A, Hirase H, Buzsáki G. 1998. Monosynaptic interactions
between CA1 Pyramidal cells and interneuron in the behaving rat. European Journal
of Neuroscience. 10(Suppl. 10), 2553–2553.
mla: Csicsvari, Jozsef L., et al. “Monosynaptic Interactions between CA1 Pyramidal
Cells and Interneuron in the Behaving Rat.” European Journal of Neuroscience,
vol. 10, no. Suppl. 10, Wiley-Blackwell, 1998, pp. 2553–2553.
short: J.L. Csicsvari, A. Czurkó, H. Hirase, G. Buzsáki, European Journal of Neuroscience
10 (1998) 2553–2553.
date_created: 2018-12-11T12:03:48Z
date_published: 1998-06-01T00:00:00Z
date_updated: 2021-01-12T07:44:05Z
day: '01'
extern: 1
intvolume: ' 10'
issue: Suppl. 10
month: '06'
page: 2553 - 2553
publication: European Journal of Neuroscience
publication_status: published
publisher: Wiley-Blackwell
publist_id: '2858'
quality_controlled: 0
status: public
title: Monosynaptic interactions between CA1 Pyramidal cells and interneuron in the
behaving rat
type: journal_article
volume: 10
year: '1998'
...
---
_id: '3535'
author:
- first_name: Hajima
full_name: Hirase, Hajima
last_name: Hirase
- first_name: András
full_name: Czurkó, András
last_name: Czurkó
- first_name: Jozsef L
full_name: Jozsef Csicsvari
id: 3FA14672-F248-11E8-B48F-1D18A9856A87
last_name: Csicsvari
orcid: 0000-0002-5193-4036
- first_name: György
full_name: Buzsáki, György
last_name: Buzsáki
citation:
ama: 'Hirase H, Czurkó A, Csicsvari JL, Buzsáki G. Hippocampal pyramidal neutrons
“space-clamped” in a running wheel task: Place cells or path integrators? European
Journal of Neuroscience. 1998;10(Suppl. 10):9932-9932.'
apa: 'Hirase, H., Czurkó, A., Csicsvari, J. L., & Buzsáki, G. (1998). Hippocampal
pyramidal neutrons “space-clamped” in a running wheel task: Place cells or path
integrators? European Journal of Neuroscience. Wiley-Blackwell.'
chicago: 'Hirase, Hajima, András Czurkó, Jozsef L Csicsvari, and György Buzsáki.
“Hippocampal Pyramidal Neutrons ‘Space-Clamped’ in a Running Wheel Task: Place
Cells or Path Integrators?” European Journal of Neuroscience. Wiley-Blackwell,
1998.'
ieee: 'H. Hirase, A. Czurkó, J. L. Csicsvari, and G. Buzsáki, “Hippocampal pyramidal
neutrons ‘space-clamped’ in a running wheel task: Place cells or path integrators?,”
European Journal of Neuroscience, vol. 10, no. Suppl. 10. Wiley-Blackwell,
pp. 9932–9932, 1998.'
ista: 'Hirase H, Czurkó A, Csicsvari JL, Buzsáki G. 1998. Hippocampal pyramidal
neutrons “space-clamped” in a running wheel task: Place cells or path integrators?
European Journal of Neuroscience. 10(Suppl. 10), 9932–9932.'
mla: 'Hirase, Hajima, et al. “Hippocampal Pyramidal Neutrons ‘Space-Clamped’ in
a Running Wheel Task: Place Cells or Path Integrators?” European Journal of
Neuroscience, vol. 10, no. Suppl. 10, Wiley-Blackwell, 1998, pp. 9932–9932.'
short: H. Hirase, A. Czurkó, J.L. Csicsvari, G. Buzsáki, European Journal of Neuroscience
10 (1998) 9932–9932.
date_created: 2018-12-11T12:03:50Z
date_published: 1998-01-01T00:00:00Z
date_updated: 2021-01-12T07:44:08Z
day: '01'
extern: 1
intvolume: ' 10'
issue: Suppl. 10
month: '01'
page: 9932 - 9932
publication: European Journal of Neuroscience
publication_status: published
publisher: Wiley-Blackwell
publist_id: '2850'
quality_controlled: 0
status: public
title: 'Hippocampal pyramidal neutrons “space-clamped” in a running wheel task: Place
cells or path integrators?'
type: journal_article
volume: 10
year: '1998'
...
---
_id: '3570'
abstract:
- lang: eng
text: Visualization of high-dimensional or large geometric data sets is inherently
difficult, so we experiment with the use of audio to display the shape and connectivity
of these data sets. Sonification is used as both an addition to and a substitution
for the visual display. We describe a new algorithm called wave traversal that
provides a necessary intermediate step to sonification of the data; it produces
an ordered sequence of subsets, called waves, that allows us to map the data to
time. In this paper we focus in detail on the mathematics of wave traversal, in
particular, how wave traversal can be used as a discrete Morse function.
article_processing_charge: No
author:
- first_name: Ulrike
full_name: Axen, Ulrike
last_name: Axen
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
citation:
ama: 'Axen U, Edelsbrunner H. Auditory Morse analysis of triangulated manifolds.
In: Mathematical Visualization. Springer; 1998:223-236. doi:10.1007/978-3-662-03567-2_17'
apa: Axen, U., & Edelsbrunner, H. (1998). Auditory Morse analysis of triangulated
manifolds. In Mathematical Visualization (pp. 223–236). Springer. https://doi.org/10.1007/978-3-662-03567-2_17
chicago: Axen, Ulrike, and Herbert Edelsbrunner. “Auditory Morse Analysis of Triangulated
Manifolds.” In Mathematical Visualization, 223–36. Springer, 1998. https://doi.org/10.1007/978-3-662-03567-2_17.
ieee: U. Axen and H. Edelsbrunner, “Auditory Morse analysis of triangulated manifolds,”
in Mathematical Visualization, Springer, 1998, pp. 223–236.
ista: 'Axen U, Edelsbrunner H. 1998.Auditory Morse analysis of triangulated manifolds.
In: Mathematical Visualization. , 223–236.'
mla: Axen, Ulrike, and Herbert Edelsbrunner. “Auditory Morse Analysis of Triangulated
Manifolds.” Mathematical Visualization, Springer, 1998, pp. 223–36, doi:10.1007/978-3-662-03567-2_17.
short: U. Axen, H. Edelsbrunner, in:, Mathematical Visualization, Springer, 1998,
pp. 223–236.
date_created: 2018-12-11T12:04:01Z
date_published: 1998-10-20T00:00:00Z
date_updated: 2022-08-29T12:47:32Z
day: '20'
doi: 10.1007/978-3-662-03567-2_17
extern: '1'
language:
- iso: eng
month: '10'
oa_version: None
page: 223 - 236
publication: Mathematical Visualization
publication_identifier:
isbn:
- '9783662035672'
publication_status: published
publisher: Springer
publist_id: '2815'
quality_controlled: '1'
status: public
title: Auditory Morse analysis of triangulated manifolds
type: book_chapter
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
year: '1998'
...
---
_id: '3627'
abstract:
- lang: eng
text: When a favourable mutation sweeps to fixation, those genes initially linked
to it increase in frequency; on average, this reduces diversity in the surrounding
region of the genome. In the first analysis of this 'hitch-hiking' effect, Maynard-Smith
and Haigh followed the increase of the neutral allele that chanced to be associated
with the new mutation in the first generation, and assumed that the subsequent
increase was deterministic. Later analyses, based on either coalescence arguments,
or on diffusion equations for the mean and variance of allele frequency, have
also made one or both of these assumptions. In the early generations, stochastic
fluctuations in the frequency of the selected allele, and coalescence of neutral
lineages, can be accounted for correctly by following relationships between genes
conditional on the number of copies of the favourable allele. This analysis shows
that the hitch-hiking effect is increased because an allele that is destined to
fix tends to increase more rapidly than exponentially. However, the identity generated
by the selective sweep has the same form as in previous work, h[r/s] (2 Ns)(-2r/s),
where h[r/s] tends to 1 with tight linkage. This analysis is extended to samples
of many genes; then, genes may trace back to several families of lineages, each
related through a common ancestor early in the selective sweep. Simulations show
that the number and sizes of these families can (in principle) be used to make
separate estimates of r/s and Ns.
acknowledgement: S. P. Otto kindly supplied the simulation results shown in Fig. 1.
I would like to thank B. Charlesworth, A. Etheridge and S. P. Otto for their comments
on the manuscript. This work was supported by the Biotechnology and Biological Sciences
Research Council, and by the Darwin Trust of Edinburgh.
article_processing_charge: No
article_type: original
author:
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
citation:
ama: Barton NH. The effect of hitch-hiking on neutral genealogies. Genetical
Research. 1998;72(2):123-133. doi:10.1017/S0016672398003462
apa: Barton, N. H. (1998). The effect of hitch-hiking on neutral genealogies. Genetical
Research. Cambridge University Press. https://doi.org/10.1017/S0016672398003462
chicago: Barton, Nicholas H. “The Effect of Hitch-Hiking on Neutral Genealogies.”
Genetical Research. Cambridge University Press, 1998. https://doi.org/10.1017/S0016672398003462.
ieee: N. H. Barton, “The effect of hitch-hiking on neutral genealogies,” Genetical
Research, vol. 72, no. 2. Cambridge University Press, pp. 123–133, 1998.
ista: Barton NH. 1998. The effect of hitch-hiking on neutral genealogies. Genetical
Research. 72(2), 123–133.
mla: Barton, Nicholas H. “The Effect of Hitch-Hiking on Neutral Genealogies.” Genetical
Research, vol. 72, no. 2, Cambridge University Press, 1998, pp. 123–33, doi:10.1017/S0016672398003462.
short: N.H. Barton, Genetical Research 72 (1998) 123–133.
date_created: 2018-12-11T12:04:19Z
date_published: 1998-10-01T00:00:00Z
date_updated: 2022-08-29T12:42:44Z
day: '01'
doi: 10.1017/S0016672398003462
extern: '1'
intvolume: ' 72'
issue: '2'
language:
- iso: eng
month: '10'
oa_version: None
page: 123 - 133
publication: Genetical Research
publication_identifier:
issn:
- 0016-6723
publication_status: published
publisher: Cambridge University Press
publist_id: '2756'
quality_controlled: '1'
scopus_import: '1'
status: public
title: The effect of hitch-hiking on neutral genealogies
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 72
year: '1998'
...
---
_id: '3628'
abstract:
- lang: eng
text: 'Determining the way in which deleterious mutations interact in their effects
on fitness is crucial to numerous areas in population genetics and evolutionary
biology. For example, if each additional mutation leads to a greater decrease
in log fitness than the last (synergistic epistasis), then the evolution of sex
and recombination may be favored to facilitate the elimination of deleterious
mutations. However, there is a severe shortage of relevant data. Three relatively
simple experimental methods to test for epistasis between deleterious mutations
in haploid species have recently been proposed. These methods involve crossing
individuals and examining the mean and/or skew in log fitness of the offspring
and parents. The main aim of this paper is to formalize these methods, and determine
the most effective way in which tests for epistasis could be carried out. We show
that only one of these methods is likely to give useful results: crossing individuals
that have very different numbers of deleterious mutations, and comparing the mean
log fitness of the parents with that of their offspring. We also reconsider experimental
data collected on Chlamydomonas moewussi using two of the three methods. Finally,
we suggest how the test could be applied to diploid species.'
acknowledgement: We thank BRIAN CHARLESWORTH, ANDREW CLARK, LAURENCE HURST, PETER KEIGHTLEY,
ALEXEY KONDRASHOV, CURT LIVELY, MARGARET MACKINNON, KATRINA LYTHGOE, SALLY OTTO,
ANDREW READ and ARJAN DE VISSER for useful discussion and comments on the manuscript.
This work was supported by the Biotechnology and Biological Sciences Research Council.
article_processing_charge: No
article_type: original
author:
- first_name: Stuart
full_name: West, Stuart
last_name: West
- first_name: Andrew
full_name: Peters, Andrew
last_name: Peters
- first_name: Nicholas H
full_name: Barton, Nicholas H
id: 4880FE40-F248-11E8-B48F-1D18A9856A87
last_name: Barton
orcid: 0000-0002-8548-5240
citation:
ama: West S, Peters A, Barton NH. Testing for epistasis between deleterious mutations.
Genetics. 1998;149(1):435-444. doi:10.1093/genetics/149.1.435
apa: West, S., Peters, A., & Barton, N. H. (1998). Testing for epistasis between
deleterious mutations. Genetics. Genetics Society of America. https://doi.org/10.1093/genetics/149.1.435
chicago: West, Stuart, Andrew Peters, and Nicholas H Barton. “Testing for Epistasis
between Deleterious Mutations.” Genetics. Genetics Society of America,
1998. https://doi.org/10.1093/genetics/149.1.435.
ieee: S. West, A. Peters, and N. H. Barton, “Testing for epistasis between deleterious
mutations,” Genetics, vol. 149, no. 1. Genetics Society of America, pp.
435–444, 1998.
ista: West S, Peters A, Barton NH. 1998. Testing for epistasis between deleterious
mutations. Genetics. 149(1), 435–444.
mla: West, Stuart, et al. “Testing for Epistasis between Deleterious Mutations.”
Genetics, vol. 149, no. 1, Genetics Society of America, 1998, pp. 435–44,
doi:10.1093/genetics/149.1.435.
short: S. West, A. Peters, N.H. Barton, Genetics 149 (1998) 435–444.
date_created: 2018-12-11T12:04:19Z
date_published: 1998-05-01T00:00:00Z
date_updated: 2022-08-29T08:53:09Z
day: '01'
doi: 10.1093/genetics/149.1.435
extern: '1'
external_id:
pmid:
- '9584115'
intvolume: ' 149'
issue: '1'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://academic.oup.com/genetics/article/149/1/435/6034229
month: '05'
oa: 1
oa_version: None
page: 435 - 444
pmid: 1
publication: Genetics
publication_identifier:
issn:
- 0016-6731
publication_status: published
publisher: Genetics Society of America
publist_id: '2755'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Testing for epistasis between deleterious mutations
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 149
year: '1998'
...