---
_id: '11893'
abstract:
- lang: eng
  text: "We present fully dynamic algorithms for maintaining the biconnected components
    in general and plane graphs.\r\n\r\nA fully dynamic algorithm maintains a graph
    during a sequence of insertions and deletions of edges or isolated vertices. Let
    m be the number of edges and n be the number of vertices in a graph. The time
    per operation of the best deterministic algorithms is \U0001D442(\U0001D45B√)
    in general graphs and O(log n) in plane graphs for fully dynamic connectivity
    and O(min m2/3 ,n}) in general graphs and \U0001D442(\U0001D45B√) in plane graphs
    for fully dynamic biconnectivity. We improve the later running times to \U0001D442(\U0001D45Alog\U0001D45B‾‾‾‾‾‾‾√)
    in general graphs and O(log 2n ) in plane graphs. Our algorithm for general graphscan
    also find the biconnected components of all vertices in time O(n)."
article_processing_charge: No
article_type: original
author:
- first_name: Monika H
  full_name: Henzinger, Monika H
  id: 540c9bbd-f2de-11ec-812d-d04a5be85630
  last_name: Henzinger
  orcid: 0000-0002-5008-6530
citation:
  ama: Henzinger MH. Improved data structures for fully dynamic biconnectivity. <i>SIAM
    Journal on Computing</i>. 2000;29(6):1761-1815. doi:<a href="https://doi.org/10.1137/s0097539794263907">10.1137/s0097539794263907</a>
  apa: Henzinger, M. H. (2000). Improved data structures for fully dynamic biconnectivity.
    <i>SIAM Journal on Computing</i>. Society for Industrial &#38; Applied Mathematics.
    <a href="https://doi.org/10.1137/s0097539794263907">https://doi.org/10.1137/s0097539794263907</a>
  chicago: Henzinger, Monika H. “Improved Data Structures for Fully Dynamic Biconnectivity.”
    <i>SIAM Journal on Computing</i>. Society for Industrial &#38; Applied Mathematics,
    2000. <a href="https://doi.org/10.1137/s0097539794263907">https://doi.org/10.1137/s0097539794263907</a>.
  ieee: M. H. Henzinger, “Improved data structures for fully dynamic biconnectivity,”
    <i>SIAM Journal on Computing</i>, vol. 29, no. 6. Society for Industrial &#38;
    Applied Mathematics, pp. 1761–1815, 2000.
  ista: Henzinger MH. 2000. Improved data structures for fully dynamic biconnectivity.
    SIAM Journal on Computing. 29(6), 1761–1815.
  mla: Henzinger, Monika H. “Improved Data Structures for Fully Dynamic Biconnectivity.”
    <i>SIAM Journal on Computing</i>, vol. 29, no. 6, Society for Industrial &#38;
    Applied Mathematics, 2000, pp. 1761–815, doi:<a href="https://doi.org/10.1137/s0097539794263907">10.1137/s0097539794263907</a>.
  short: M.H. Henzinger, SIAM Journal on Computing 29 (2000) 1761–1815.
date_created: 2022-08-17T08:45:41Z
date_published: 2000-11-01T00:00:00Z
date_updated: 2023-02-17T14:39:47Z
day: '01'
doi: 10.1137/s0097539794263907
extern: '1'
intvolume: '        29'
issue: '6'
language:
- iso: eng
month: '11'
oa_version: None
page: 1761-1815
publication: SIAM Journal on Computing
publication_identifier:
  eissn:
  - 1095-7111
  issn:
  - 0097-5397
publication_status: published
publisher: Society for Industrial & Applied Mathematics
quality_controlled: '1'
scopus_import: '1'
status: public
title: Improved data structures for fully dynamic biconnectivity
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 29
year: '2000'
...
---
_id: '12925'
abstract:
- lang: eng
  text: Normal function of organs and cells is tightly linked to the cytoarchitecture.
    Control of the cell volume is therefore vital for the organism. A widely established
    strategy of cells to counteract swelling is the activation of chloride and potassium
    channels, which leads to a net efflux of salt followed by water - a process termed
    regulatory volume decrease. Since there is evidence for swelling-dependent chloride
    channels (IClswell) being activated also during pathological processes, the identification
    of the molecular entity underlying IClswell is of utmost importance. Several proteins
    are discussed as the channel forming IClswell, i.e. phospholemman, p-glycoprotein,
    CLC-3 and ICln. In this review we would like to focus on the properties of ICln,
    a protein cloned from a Madin Darby canine kidney (MDCK) cell library whose expression
    in Xenopus laevis oocytes resulted in a nucleotide sensitive outwardly rectifying
    chloride current closely resembling the biophysical properties of IClswell.
article_processing_charge: No
article_type: original
author:
- first_name: Johannes
  full_name: Fürst, Johannes
  last_name: Fürst
- first_name: Martin
  full_name: Jakab, Martin
  last_name: Jakab
- first_name: Matthias
  full_name: König, Matthias
  last_name: König
- first_name: Markus
  full_name: Ritter, Markus
  last_name: Ritter
- first_name: Martin
  full_name: Gschwentner, Martin
  last_name: Gschwentner
- first_name: Jakob
  full_name: Rudzki, Jakob
  last_name: Rudzki
- first_name: Johann G
  full_name: Danzl, Johann G
  id: 42EFD3B6-F248-11E8-B48F-1D18A9856A87
  last_name: Danzl
  orcid: 0000-0001-8559-3973
- first_name: Michael
  full_name: Mayer, Michael
  last_name: Mayer
- first_name: Carmen M.
  full_name: Burtscher, Carmen M.
  last_name: Burtscher
- first_name: Julia
  full_name: Schirmer, Julia
  last_name: Schirmer
- first_name: Brigitte
  full_name: Maier, Brigitte
  last_name: Maier
- first_name: Manfred
  full_name: Nairz, Manfred
  last_name: Nairz
- first_name: Sabine
  full_name: Chwatal, Sabine
  last_name: Chwatal
- first_name: Markus
  full_name: Paulmichl, Markus
  last_name: Paulmichl
citation:
  ama: Fürst J, Jakab M, König M, et al. Structure and Function of the Ion Channel
    ICln. <i>Cellular Physiology and Biochemistry</i>. 2000;10(5-6):329-334. doi:<a
    href="https://doi.org/10.1159/000016374">10.1159/000016374</a>
  apa: Fürst, J., Jakab, M., König, M., Ritter, M., Gschwentner, M., Rudzki, J., …
    Paulmichl, M. (2000). Structure and Function of the Ion Channel ICln. <i>Cellular
    Physiology and Biochemistry</i>. S. Karger AG. <a href="https://doi.org/10.1159/000016374">https://doi.org/10.1159/000016374</a>
  chicago: Fürst, Johannes, Martin Jakab, Matthias König, Markus Ritter, Martin Gschwentner,
    Jakob Rudzki, Johann G Danzl, et al. “Structure and Function of the Ion Channel
    ICln.” <i>Cellular Physiology and Biochemistry</i>. S. Karger AG, 2000. <a href="https://doi.org/10.1159/000016374">https://doi.org/10.1159/000016374</a>.
  ieee: J. Fürst <i>et al.</i>, “Structure and Function of the Ion Channel ICln,”
    <i>Cellular Physiology and Biochemistry</i>, vol. 10, no. 5–6. S. Karger AG, pp.
    329–334, 2000.
  ista: Fürst J, Jakab M, König M, Ritter M, Gschwentner M, Rudzki J, Danzl JG, Mayer
    M, Burtscher CM, Schirmer J, Maier B, Nairz M, Chwatal S, Paulmichl M. 2000. Structure
    and Function of the Ion Channel ICln. Cellular Physiology and Biochemistry. 10(5–6),
    329–334.
  mla: Fürst, Johannes, et al. “Structure and Function of the Ion Channel ICln.” <i>Cellular
    Physiology and Biochemistry</i>, vol. 10, no. 5–6, S. Karger AG, 2000, pp. 329–34,
    doi:<a href="https://doi.org/10.1159/000016374">10.1159/000016374</a>.
  short: J. Fürst, M. Jakab, M. König, M. Ritter, M. Gschwentner, J. Rudzki, J.G.
    Danzl, M. Mayer, C.M. Burtscher, J. Schirmer, B. Maier, M. Nairz, S. Chwatal,
    M. Paulmichl, Cellular Physiology and Biochemistry 10 (2000) 329–334.
date_created: 2023-05-08T09:04:58Z
date_published: 2000-01-01T00:00:00Z
date_updated: 2023-05-08T10:07:10Z
doi: 10.1159/000016374
extern: '1'
external_id:
  pmid:
  - '11125213'
intvolume: '        10'
issue: 5-6
keyword:
- Physiology
language:
- iso: eng
oa_version: None
page: 329-334
pmid: 1
publication: Cellular Physiology and Biochemistry
publication_identifier:
  issn:
  - 1015-8987
  - 1421-9778
publication_status: published
publisher: S. Karger AG
quality_controlled: '1'
scopus_import: '1'
status: public
title: Structure and Function of the Ion Channel ICln
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 10
year: '2000'
...
---
_id: '3489'
abstract:
- lang: eng
  text: We have examined factors that determine the strength and dynamics of GABAergic
    synapses between interneurons [dentate gyrus basket cells (BCs)] and principal
    neurons [dentate gyrus granule cells (GCs)] using paired recordings in rat hippocampal
    slices at 34°C. Unitary IPSCs recorded from BC–GC pairs in high intracellular
    Cl− concentration showed a fast rise and a biexponential decay, with mean time
    constants of 2 and 9 msec. The mean quantal conductance change, determined directly
    at reduced extracellular Ca2+/Mg2+concentration ratios, was 1.7 nS. Quantal release
    at the BC–GC synapse occurred with short delay and was highly synchronized. Analysis
    of IPSC peak amplitudes and numbers of failures by multiple probability compound
    binomial analysis indicated that synaptic transmission at the BC–GC synapse involves
    three to seven release sites, each of which releases transmitter with high probability
    (∼0.5 in 2 mMCa2+/1 mM Mg2+). Unitary BC–GC IPSCs showed paired-pulse depression
    (PPD); maximal depression, measured for 10 msec intervals, was 37%, and recovery
    from depression occurred with a time constant of 2 sec. Paired-pulse depression
    was mainly presynaptic in origin but appeared to be independent of previous release.
    Synaptic transmission at the BC–GC synapse showed frequency-dependent depression,
    with half-maximal decrease at 5 Hz after a series of 1000 presynaptic action potentials.
    The relative stability of transmission at the BC–GC synapse is consistent with
    a model in which an activity-dependent gating mechanism reduces release probability
    and thereby prevents depletion of the releasable pool of synaptic vesicles. Thus
    several mechanisms converge on the generation of powerful and sustained transmission
    at interneuron–principal neuron synapses in hippocampal circuits.
acknowledgement: This work was supported by grants from the Deutsche Forschungsgemeinschaft
  (SFB 505/C5) and the Human Frontiers Science Program Organization (RG0017/1998-B)
  to P.J. Novartis generously provided CGP55845A. We thank Drs. J. Bischofberger,
  F. A. Edwards, J. R. P. Geiger, M. V. Jones, M. Martina, and A. Roth for critically
  reading this manuscript. We also thank A. Blomenkamp for technical assistance.
article_processing_charge: No
article_type: original
author:
- first_name: Udo
  full_name: Kraushaar, Udo
  last_name: Kraushaar
- first_name: Peter M
  full_name: Jonas, Peter M
  id: 353C1B58-F248-11E8-B48F-1D18A9856A87
  last_name: Jonas
  orcid: 0000-0001-5001-4804
citation:
  ama: Kraushaar U, Jonas PM. Efficacy and stability of quantal GABA release at a
    hippocampal interneuron-principal neuron synapse. <i>Journal of Neuroscience</i>.
    2000;20(15):5594-5607. doi:<a href="https://doi.org/10.1523/JNEUROSCI.20-15-05594.2000">10.1523/JNEUROSCI.20-15-05594.2000</a>
  apa: Kraushaar, U., &#38; Jonas, P. M. (2000). Efficacy and stability of quantal
    GABA release at a hippocampal interneuron-principal neuron synapse. <i>Journal
    of Neuroscience</i>. Society for Neuroscience. <a href="https://doi.org/10.1523/JNEUROSCI.20-15-05594.2000">https://doi.org/10.1523/JNEUROSCI.20-15-05594.2000</a>
  chicago: Kraushaar, Udo, and Peter M Jonas. “Efficacy and Stability of Quantal GABA
    Release at a Hippocampal Interneuron-Principal Neuron Synapse.” <i>Journal of
    Neuroscience</i>. Society for Neuroscience, 2000. <a href="https://doi.org/10.1523/JNEUROSCI.20-15-05594.2000">https://doi.org/10.1523/JNEUROSCI.20-15-05594.2000</a>.
  ieee: U. Kraushaar and P. M. Jonas, “Efficacy and stability of quantal GABA release
    at a hippocampal interneuron-principal neuron synapse,” <i>Journal of Neuroscience</i>,
    vol. 20, no. 15. Society for Neuroscience, pp. 5594–5607, 2000.
  ista: Kraushaar U, Jonas PM. 2000. Efficacy and stability of quantal GABA release
    at a hippocampal interneuron-principal neuron synapse. Journal of Neuroscience.
    20(15), 5594–5607.
  mla: Kraushaar, Udo, and Peter M. Jonas. “Efficacy and Stability of Quantal GABA
    Release at a Hippocampal Interneuron-Principal Neuron Synapse.” <i>Journal of
    Neuroscience</i>, vol. 20, no. 15, Society for Neuroscience, 2000, pp. 5594–607,
    doi:<a href="https://doi.org/10.1523/JNEUROSCI.20-15-05594.2000">10.1523/JNEUROSCI.20-15-05594.2000</a>.
  short: U. Kraushaar, P.M. Jonas, Journal of Neuroscience 20 (2000) 5594–5607.
date_created: 2018-12-11T12:03:36Z
date_published: 2000-08-01T00:00:00Z
date_updated: 2023-05-03T08:18:39Z
day: '01'
doi: 10.1523/JNEUROSCI.20-15-05594.2000
extern: '1'
external_id:
  pmid:
  - '10908596'
intvolume: '        20'
issue: '15'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6772523/
month: '08'
oa: 1
oa_version: Published Version
page: 5594 - 5607
pmid: 1
publication: Journal of Neuroscience
publication_identifier:
  issn:
  - 0270-6474
publication_status: published
publisher: Society for Neuroscience
publist_id: '2898'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Efficacy and stability of quantal GABA release at a hippocampal interneuron-principal
  neuron synapse
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 20
year: '2000'
...
---
_id: '3490'
abstract:
- lang: eng
  text: Long-term depression (LTD) is a form of synaptic plasticity that can be induced
    either by low-frequency stimulation of presynaptic fibers or in an associative
    manner by asynchronous pairing of presynaptic and postsynaptic activity. We investigated
    the induction mechanisms of associative LTD in CA1 pyramidal neurons of the hippocampus
    using whole-cell patch-clamp recordings and Ca2+ imaging in acute brain slices.
    Asynchronous pairing of postsynaptic action potentials with EPSPs evoked with
    a delay of 20 msec induced a robust, long-lasting depression of the EPSP amplitude
    to 43%. Unlike LTD induced by low-frequency stimulation, associative LTD was resistant
    to the application of D-AP-5, indicating that it is independent of NMDA receptors.
    In contrast, associative LTD was inhibited by (S)-α-methyl-4-carboxyphenyl-glycine,
    indicating the involvement of metabotropic glutamate receptors. Furthermore, associative
    LTD is dependent on the activation of voltage-gated Ca2+ channels by postsynaptic
    action potentials. Both nifedipine, an L-type Ca2+ channel antagonist, and ω-conotoxin
    GVIA, a selective N-type channel blocker, abolished the induction of associative
    LTD. 8-hydroxy-2-dipropylaminotetralin (OH-DPAT), a 5-HT(1A) receptor agonist,
    inhibited postsynaptic Ca2+ influx through N-type Ca2+ channels, without affecting
    presynaptic transmitter release. OH-DPAT also inhibited the induction of associative
    LTD, suggesting that the involvement of N-type channels makes synaptic plasticity
    accessible to modulation by neurotransmitters. Thus, the modulation of N-type
    Ca2+ channels provides a gain control for synaptic depression in hippocampal pyramidal
    neurons.
acknowledgement: This work was supported by a grant from the Deutsche Forschungsgemeinschaft
  Bi 642/1–2 and University funds (J.B.) and by the Vada and Theodore Stanley Foundation
  (J.W.). We thank Drs. M. Bartos, J. R. P. Geiger, and M. Martina for critically
  reading this manuscript and A. Blomenkamp for technical assistance.
article_processing_charge: No
article_type: original
author:
- first_name: Claus
  full_name: Normann, Claus
  last_name: Normann
- first_name: Diana
  full_name: Peckys, Diana
  last_name: Peckys
- first_name: Christian
  full_name: Schulze, Christian
  last_name: Schulze
- first_name: Jörg
  full_name: Walden, Jörg
  last_name: Walden
- first_name: Peter M
  full_name: Jonas, Peter M
  id: 353C1B58-F248-11E8-B48F-1D18A9856A87
  last_name: Jonas
  orcid: 0000-0001-5001-4804
- first_name: Joseph
  full_name: Bischofberger, Joseph
  last_name: Bischofberger
citation:
  ama: Normann C, Peckys D, Schulze C, Walden J, Jonas PM, Bischofberger J. Associative
    long-term depression in the hippocampus is dependent on postsynaptic N-type Ca(2+)
    channels. <i>Journal of Neuroscience</i>. 2000;20(22):8290-8297. doi:<a href="https://doi.org/10.1523/JNEUROSCI.20-22-08290.2000">10.1523/JNEUROSCI.20-22-08290.2000</a>
  apa: Normann, C., Peckys, D., Schulze, C., Walden, J., Jonas, P. M., &#38; Bischofberger,
    J. (2000). Associative long-term depression in the hippocampus is dependent on
    postsynaptic N-type Ca(2+) channels. <i>Journal of Neuroscience</i>. Society for
    Neuroscience. <a href="https://doi.org/10.1523/JNEUROSCI.20-22-08290.2000">https://doi.org/10.1523/JNEUROSCI.20-22-08290.2000</a>
  chicago: Normann, Claus, Diana Peckys, Christian Schulze, Jörg Walden, Peter M Jonas,
    and Joseph Bischofberger. “Associative Long-Term Depression in the Hippocampus
    Is Dependent on Postsynaptic N-Type Ca(2+) Channels.” <i>Journal of Neuroscience</i>.
    Society for Neuroscience, 2000. <a href="https://doi.org/10.1523/JNEUROSCI.20-22-08290.2000">https://doi.org/10.1523/JNEUROSCI.20-22-08290.2000</a>.
  ieee: C. Normann, D. Peckys, C. Schulze, J. Walden, P. M. Jonas, and J. Bischofberger,
    “Associative long-term depression in the hippocampus is dependent on postsynaptic
    N-type Ca(2+) channels,” <i>Journal of Neuroscience</i>, vol. 20, no. 22. Society
    for Neuroscience, pp. 8290–8297, 2000.
  ista: Normann C, Peckys D, Schulze C, Walden J, Jonas PM, Bischofberger J. 2000.
    Associative long-term depression in the hippocampus is dependent on postsynaptic
    N-type Ca(2+) channels. Journal of Neuroscience. 20(22), 8290–8297.
  mla: Normann, Claus, et al. “Associative Long-Term Depression in the Hippocampus
    Is Dependent on Postsynaptic N-Type Ca(2+) Channels.” <i>Journal of Neuroscience</i>,
    vol. 20, no. 22, Society for Neuroscience, 2000, pp. 8290–97, doi:<a href="https://doi.org/10.1523/JNEUROSCI.20-22-08290.2000">10.1523/JNEUROSCI.20-22-08290.2000</a>.
  short: C. Normann, D. Peckys, C. Schulze, J. Walden, P.M. Jonas, J. Bischofberger,
    Journal of Neuroscience 20 (2000) 8290–8297.
date_created: 2018-12-11T12:03:36Z
date_published: 2000-11-15T00:00:00Z
date_updated: 2023-05-03T08:02:52Z
day: '15'
doi: 10.1523/JNEUROSCI.20-22-08290.2000
extern: '1'
external_id:
  pmid:
  - '11069935'
intvolume: '        20'
issue: '22'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773198/
month: '11'
oa: 1
oa_version: Published Version
page: 8290 - 8297
pmid: 1
publication: Journal of Neuroscience
publication_identifier:
  issn:
  - 0270-6474
publication_status: published
publisher: Society for Neuroscience
publist_id: '2897'
quality_controlled: '1'
status: public
title: Associative long-term depression in the hippocampus is dependent on postsynaptic
  N-type Ca(2+) channels
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 20
year: '2000'
...
---
_id: '3491'
abstract:
- lang: eng
  text: Fast and reliable activation of inhibitory interneurons is critical for the
    stability of cortical neuronal networks. Active conductances in dendrites may
    facilitate interneuron activation, but direct experimental evidence was unavailable.
    Patch-clamp recordings from dendrites of hippocampal oriens- alveus interneurons
    revealed high densities of voltage-gated sodium and potassium ion channels. Simultaneous
    recordings from dendrites and somata suggested that action potential initiation
    occurs preferentially in the axon with long threshold stimuli, but can be shifted
    to somatodendritic sites when brief stimuli are applied. After initiation, action
    potentials propagate over the somatodendritic domain with constant amplitude,
    high velocity, and reliability, even during high-frequency trains.
article_processing_charge: No
article_type: original
author:
- first_name: Marco
  full_name: Martina, Marco
  last_name: Martina
- first_name: Imre
  full_name: Vida, Imre
  last_name: Vida
- first_name: Peter M
  full_name: Jonas, Peter M
  id: 353C1B58-F248-11E8-B48F-1D18A9856A87
  last_name: Jonas
  orcid: 0000-0001-5001-4804
citation:
  ama: Martina M, Vida I, Jonas PM. Distal initiation and active propagation of action
    potentials in interneuron dendrites. <i>Science</i>. 2000;287(5451):295-300. doi:<a
    href="https://doi.org/10.1126/science.287.5451.295">10.1126/science.287.5451.295</a>
  apa: Martina, M., Vida, I., &#38; Jonas, P. M. (2000). Distal initiation and active
    propagation of action potentials in interneuron dendrites. <i>Science</i>. American
    Association for the Advancement of Science. <a href="https://doi.org/10.1126/science.287.5451.295">https://doi.org/10.1126/science.287.5451.295</a>
  chicago: Martina, Marco, Imre Vida, and Peter M Jonas. “Distal Initiation and Active
    Propagation of Action Potentials in Interneuron Dendrites.” <i>Science</i>. American
    Association for the Advancement of Science, 2000. <a href="https://doi.org/10.1126/science.287.5451.295">https://doi.org/10.1126/science.287.5451.295</a>.
  ieee: M. Martina, I. Vida, and P. M. Jonas, “Distal initiation and active propagation
    of action potentials in interneuron dendrites,” <i>Science</i>, vol. 287, no.
    5451. American Association for the Advancement of Science, pp. 295–300, 2000.
  ista: Martina M, Vida I, Jonas PM. 2000. Distal initiation and active propagation
    of action potentials in interneuron dendrites. Science. 287(5451), 295–300.
  mla: Martina, Marco, et al. “Distal Initiation and Active Propagation of Action
    Potentials in Interneuron Dendrites.” <i>Science</i>, vol. 287, no. 5451, American
    Association for the Advancement of Science, 2000, pp. 295–300, doi:<a href="https://doi.org/10.1126/science.287.5451.295">10.1126/science.287.5451.295</a>.
  short: M. Martina, I. Vida, P.M. Jonas, Science 287 (2000) 295–300.
date_created: 2018-12-11T12:03:36Z
date_published: 2000-01-14T00:00:00Z
date_updated: 2023-05-03T07:55:32Z
day: '14'
doi: 10.1126/science.287.5451.295
extern: '1'
external_id:
  pmid:
  - '10634782'
intvolume: '       287'
issue: '5451'
language:
- iso: eng
month: '01'
oa_version: None
page: 295 - 300
pmid: 1
publication: Science
publication_identifier:
  issn:
  - 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science
publist_id: '2896'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Distal initiation and active propagation of action potentials in interneuron
  dendrites
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 287
year: '2000'
...
---
_id: '3492'
abstract:
- lang: eng
  text: Analysis of presynaptic determinants of synaptic strength has been difficult
    at cortical synapses, mainly due to the lack of direct access to presynaptic elements.
    Here we report patch-clamp recordings from mossy fiber boutons (MFBs) in rat hippocampal
    slices. The presynaptic action potential is very short during low-frequency stimulation
    but is prolonged up to 3-fold during high-frequency stimulation. Voltage-gated
    K+ channels in MFBs inactivate rapidly but recover from inactivation very slowly,
    suggesting that cumulative K+ channel inactivation mediates activity-dependent
    spike broadening. Prolongation of the presynaptic voltage waveform leads to an
    increase in the number of Ca2+ ions entering the terminal per action potential
    and to a consecutive potentiation of evoked excitatory postsynaptic currents at
    MFB-CA3 pyramidal cell synapses. Thus, inactivation of presynaptic K+ channels
    contributes to the control of efficacy of a glutamatergic synapse in the cortex.
article_processing_charge: No
article_type: original
author:
- first_name: Jörg
  full_name: Geiger, Jörg
  last_name: Geiger
- first_name: Peter M
  full_name: Jonas, Peter M
  id: 353C1B58-F248-11E8-B48F-1D18A9856A87
  last_name: Jonas
  orcid: 0000-0001-5001-4804
citation:
  ama: Geiger J, Jonas PM. Dynamic control of presynaptic Ca(2+) inflow by fast-inactivating
    K+ channels in hippocampal mossy fiber boutons. <i>Neuron</i>. 2000;28(3):927-939.
    doi:<a href="https://doi.org/10.1016/S0896-6273(00)00164-1">10.1016/S0896-6273(00)00164-1</a>
  apa: Geiger, J., &#38; Jonas, P. M. (2000). Dynamic control of presynaptic Ca(2+)
    inflow by fast-inactivating K+ channels in hippocampal mossy fiber boutons. <i>Neuron</i>.
    Elsevier. <a href="https://doi.org/10.1016/S0896-6273(00)00164-1">https://doi.org/10.1016/S0896-6273(00)00164-1</a>
  chicago: Geiger, Jörg, and Peter M Jonas. “Dynamic Control of Presynaptic Ca(2+)
    Inflow by Fast-Inactivating K+ Channels in Hippocampal Mossy Fiber Boutons.” <i>Neuron</i>.
    Elsevier, 2000. <a href="https://doi.org/10.1016/S0896-6273(00)00164-1">https://doi.org/10.1016/S0896-6273(00)00164-1</a>.
  ieee: J. Geiger and P. M. Jonas, “Dynamic control of presynaptic Ca(2+) inflow by
    fast-inactivating K+ channels in hippocampal mossy fiber boutons,” <i>Neuron</i>,
    vol. 28, no. 3. Elsevier, pp. 927–939, 2000.
  ista: Geiger J, Jonas PM. 2000. Dynamic control of presynaptic Ca(2+) inflow by
    fast-inactivating K+ channels in hippocampal mossy fiber boutons. Neuron. 28(3),
    927–939.
  mla: Geiger, Jörg, and Peter M. Jonas. “Dynamic Control of Presynaptic Ca(2+) Inflow
    by Fast-Inactivating K+ Channels in Hippocampal Mossy Fiber Boutons.” <i>Neuron</i>,
    vol. 28, no. 3, Elsevier, 2000, pp. 927–39, doi:<a href="https://doi.org/10.1016/S0896-6273(00)00164-1">10.1016/S0896-6273(00)00164-1</a>.
  short: J. Geiger, P.M. Jonas, Neuron 28 (2000) 927–939.
date_created: 2018-12-11T12:03:37Z
date_published: 2000-12-01T00:00:00Z
date_updated: 2023-05-02T14:34:37Z
day: '01'
doi: 10.1016/S0896-6273(00)00164-1
extern: '1'
external_id:
  pmid:
  - '11163277'
intvolume: '        28'
issue: '3'
language:
- iso: eng
month: '12'
oa_version: None
page: 927 - 939
pmid: 1
publication: Neuron
publication_identifier:
  issn:
  - 0896-6273
publication_status: published
publisher: Elsevier
publist_id: '2895'
quality_controlled: '1'
status: public
title: Dynamic control of presynaptic Ca(2+) inflow by fast-inactivating K+ channels
  in hippocampal mossy fiber boutons
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 28
year: '2000'
...
---
_id: '3532'
abstract:
- lang: eng
  text: Multichannel tetrode array recording in awake behaving animals provides a
    powerful method to record the activity of large numbers of neurons. The power
    of this method could be extended if further information concerning the intracellular
    state of the neurons could be extracted from the extracellularly recorded signals.
    Toward this end, we have simultaneously recorded intracellular and extracellular
    signals from hippocampal CA1 pyramidal cells and interneurons in the anesthetized
    rat. We found that several intracellular parameters can be deduced from extracellular
    spike waveforms. The width of the intracellular action potential is defined precisely
    by distinct points on the extracellular spike. Amplitude changes of the intracellular
    action potential are reflected by changes in the amplitude of the initial negative
    phase of the extracellular spike, and these amplitude changes are dependent on
    the state of the network. In addition, intracellular recordings from dendrites
    with simultaneous extracellular recordings from the soma indicate that, on average,
    action potentials are initiated in the perisomatic region and propagate to the
    dendrites at 1.68 m/s. Finally we determined that a tetrode in hippocampal area
    CA1 theoretically should be able to record electrical signals from similar to
    1,000 neurons. Of these, 60-100 neurons should generate spikes of sufficient amplitude
    to be detectable from the noise and to allow for their separation using current
    spatial clustering methods. This theoretical maximum is in contrast to the approximately
    six units that are usually detected per tetrode. From this, we conclude that a
    large percentage of hippocampal CA1 pyramidal cells are silent in any given behavioral
    condition.
acknowledgement: We thank M. Recce for comments on the manuscript and J. Hetke and
  K.Wise for supplying us with the silicon probes (1P41RR09754).This work was supported
  by National Institutes of Health Grants NS-34994,MH-54671,  and  MH-12403  (to  D.
  A. Henze), the Epilepsy Foundation of American (D. A.Henze), and an Eotvos fellowship
  (Z. Borhegyi).
article_processing_charge: No
article_type: original
author:
- first_name: Darrell
  full_name: Henze, Darrell
  last_name: Henze
- first_name: Zsolt
  full_name: Borhegyi, Zsolt
  last_name: Borhegyi
- first_name: Jozsef L
  full_name: Csicsvari, Jozsef L
  id: 3FA14672-F248-11E8-B48F-1D18A9856A87
  last_name: Csicsvari
  orcid: 0000-0002-5193-4036
- first_name: Akira
  full_name: Mamiya, Akira
  last_name: Mamiya
- first_name: Kenneth
  full_name: Harris, Kenneth
  last_name: Harris
- first_name: György
  full_name: Buzsáki, György
  last_name: Buzsáki
citation:
  ama: Henze D, Borhegyi Z, Csicsvari JL, Mamiya A, Harris K, Buzsáki G. Intracellular
    features predicted by extracellular recordings in the hippocampus in vivo. <i>Journal
    of Neurophysiology</i>. 2000;84(1):390-400. doi:<a href="https://doi.org/10.1152/jn.2000.84.1.390">10.1152/jn.2000.84.1.390</a>
  apa: Henze, D., Borhegyi, Z., Csicsvari, J. L., Mamiya, A., Harris, K., &#38; Buzsáki,
    G. (2000). Intracellular features predicted by extracellular recordings in the
    hippocampus in vivo. <i>Journal of Neurophysiology</i>. American Physiological
    Society. <a href="https://doi.org/10.1152/jn.2000.84.1.390">https://doi.org/10.1152/jn.2000.84.1.390</a>
  chicago: Henze, Darrell, Zsolt Borhegyi, Jozsef L Csicsvari, Akira Mamiya, Kenneth
    Harris, and György Buzsáki. “Intracellular Features Predicted by Extracellular
    Recordings in the Hippocampus in Vivo.” <i>Journal of Neurophysiology</i>. American
    Physiological Society, 2000. <a href="https://doi.org/10.1152/jn.2000.84.1.390">https://doi.org/10.1152/jn.2000.84.1.390</a>.
  ieee: D. Henze, Z. Borhegyi, J. L. Csicsvari, A. Mamiya, K. Harris, and G. Buzsáki,
    “Intracellular features predicted by extracellular recordings in the hippocampus
    in vivo,” <i>Journal of Neurophysiology</i>, vol. 84, no. 1. American Physiological
    Society, pp. 390–400, 2000.
  ista: Henze D, Borhegyi Z, Csicsvari JL, Mamiya A, Harris K, Buzsáki G. 2000. Intracellular
    features predicted by extracellular recordings in the hippocampus in vivo. Journal
    of Neurophysiology. 84(1), 390–400.
  mla: Henze, Darrell, et al. “Intracellular Features Predicted by Extracellular Recordings
    in the Hippocampus in Vivo.” <i>Journal of Neurophysiology</i>, vol. 84, no. 1,
    American Physiological Society, 2000, pp. 390–400, doi:<a href="https://doi.org/10.1152/jn.2000.84.1.390">10.1152/jn.2000.84.1.390</a>.
  short: D. Henze, Z. Borhegyi, J.L. Csicsvari, A. Mamiya, K. Harris, G. Buzsáki,
    Journal of Neurophysiology 84 (2000) 390–400.
date_created: 2018-12-11T12:03:49Z
date_published: 2000-07-01T00:00:00Z
date_updated: 2023-05-02T14:31:13Z
day: '01'
doi: 10.1152/jn.2000.84.1.390
extern: '1'
external_id:
  pmid:
  - '10899213'
intvolume: '        84'
issue: '1'
language:
- iso: eng
month: '07'
oa_version: None
page: 390 - 400
pmid: 1
publication: Journal of Neurophysiology
publication_identifier:
  issn:
  - 0022-3077
publication_status: published
publisher: American Physiological Society
publist_id: '2854'
quality_controlled: '1'
status: public
title: Intracellular features predicted by extracellular recordings in the hippocampus
  in vivo
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 84
year: '2000'
...
---
_id: '3542'
abstract:
- lang: eng
  text: Transfer of neuronal patterns from the CA3 to CA1 region was studied by simultaneous
    recording of neuronal ensembles in the behaving rat. A nonlinear interaction among
    pyramidal neurons was observed during sharp wave (SPW)-related population bursts,
    with stronger synchrony associated with more widespread spatial coherence. SPW
    bursts emerged in the CA3a-b subregions and spread to CA3c before invading the
    CA1 area. Synchronous discharge of &gt;10% of the CA3 within a 100 ms window was
    required to exert a detectable influence on CA1 pyramidal cells. Activity of some
    CA3 pyramidal neurons differentially predicted the ripple-related discharge of
    circumscribed groups of CA1 pyramidal cells. We suggest that, in SPW behavioral
    state, the coherent discharge of a small group of CA3 cells is the primary cause
    of spiking activity in CA1 pyramidal neurons.
article_processing_charge: No
article_type: original
author:
- first_name: Jozsef L
  full_name: Csicsvari, Jozsef L
  id: 3FA14672-F248-11E8-B48F-1D18A9856A87
  last_name: Csicsvari
  orcid: 0000-0002-5193-4036
- first_name: Hajima
  full_name: Hirase, Hajima
  last_name: Hirase
- first_name: Akira
  full_name: Mamiya, Akira
  last_name: Mamiya
- first_name: György
  full_name: Buzsáki, György
  last_name: Buzsáki
citation:
  ama: Csicsvari JL, Hirase H, Mamiya A, Buzsáki G. Ensemble patterns of hippocampal
    CA3-CA1 neurons during sharp wave-associated population events. <i>Neuron</i>.
    2000;28(2):585-594. doi:<a href="https://doi.org/10.1016/S0896-6273(00)00135-5">10.1016/S0896-6273(00)00135-5</a>
  apa: Csicsvari, J. L., Hirase, H., Mamiya, A., &#38; Buzsáki, G. (2000). Ensemble
    patterns of hippocampal CA3-CA1 neurons during sharp wave-associated population
    events. <i>Neuron</i>. Elsevier. <a href="https://doi.org/10.1016/S0896-6273(00)00135-5">https://doi.org/10.1016/S0896-6273(00)00135-5</a>
  chicago: Csicsvari, Jozsef L, Hajima Hirase, Akira Mamiya, and György Buzsáki. “Ensemble
    Patterns of Hippocampal CA3-CA1 Neurons during Sharp Wave-Associated Population
    Events.” <i>Neuron</i>. Elsevier, 2000. <a href="https://doi.org/10.1016/S0896-6273(00)00135-5">https://doi.org/10.1016/S0896-6273(00)00135-5</a>.
  ieee: J. L. Csicsvari, H. Hirase, A. Mamiya, and G. Buzsáki, “Ensemble patterns
    of hippocampal CA3-CA1 neurons during sharp wave-associated population events,”
    <i>Neuron</i>, vol. 28, no. 2. Elsevier, pp. 585–594, 2000.
  ista: Csicsvari JL, Hirase H, Mamiya A, Buzsáki G. 2000. Ensemble patterns of hippocampal
    CA3-CA1 neurons during sharp wave-associated population events. Neuron. 28(2),
    585–594.
  mla: Csicsvari, Jozsef L., et al. “Ensemble Patterns of Hippocampal CA3-CA1 Neurons
    during Sharp Wave-Associated Population Events.” <i>Neuron</i>, vol. 28, no. 2,
    Elsevier, 2000, pp. 585–94, doi:<a href="https://doi.org/10.1016/S0896-6273(00)00135-5">10.1016/S0896-6273(00)00135-5</a>.
  short: J.L. Csicsvari, H. Hirase, A. Mamiya, G. Buzsáki, Neuron 28 (2000) 585–594.
date_created: 2018-12-11T12:03:52Z
date_published: 2000-11-01T00:00:00Z
date_updated: 2023-05-02T14:26:07Z
day: '01'
doi: 10.1016/S0896-6273(00)00135-5
extern: '1'
intvolume: '        28'
issue: '2'
language:
- iso: eng
month: '11'
oa_version: None
page: 585 - 594
publication: Neuron
publication_identifier:
  issn:
  - 0896-6273
publication_status: published
publisher: Elsevier
publist_id: '2843'
quality_controlled: '1'
status: public
title: Ensemble patterns of hippocampal CA3-CA1 neurons during sharp wave-associated
  population events
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 28
year: '2000'
...
---
_id: '3548'
abstract:
- lang: eng
  text: Simultaneous recording from large numbers of neurons is a prerequisite for
    understanding their cooperative behavior. Various recording techniques and spike
    separation methods are being used toward this goal. However, the error rates involved
    in spike separation have not yet been quantified. We studied the separation reliability
    of “tetrode” (4-wire electrode) recorded spikes by monitoring simultaneously from
    the same cell intracellularly with a glass pipette and extracellularly with a
    tetrode. With manual spike sorting, we found a trade-off between Type I and Type
    II errors, with errors typically ranging from 0 to 30% depending on the amplitude
    and firing pattern of the cell, the similarity of the waveshapes of neighboring
    neurons, and the experience of the operator. Performance using only a single wire
    was markedly lower, indicating the advantages of multiple-site monitoring techniques
    over single-wire recordings. For tetrode recordings, error rates were increased
    by burst activity and during periods of cellular synchrony. The lowest possible
    separation error rates were estimated by a search for the best ellipsoidal cluster
    shape. Human operator performance was significantly below the estimated optimum.
    Investigation of error distributions indicated that suboptimal performance was
    caused by inability of the operators to mark cluster boundaries accurately in
    a high-dimensional feature space. We therefore hypothesized that automatic spike-sorting
    algorithms have the potential to significantly lower error rates. Implementation
    of a semi-automatic classification system confirms this suggestion, reducing errors
    close to the estimated optimum, in the range 0-8%.
acknowledgement: The costs of publication of this article were defrayed in part by
  the payment of page charges. The article must therefore be hereby marked ‘‘advertisement’
  ’in accordance with 18 U.S.C. Section 1734 solely to indicate this fact. We thank
  R. Bruno for performing cluster analysis and drawing our attention to the AutoClass
  program, M. Recce and P. Mitra for suggestions withdata  analysis and comments on
  the manuscript, C. King, G. Dragoi, and X.Leinekugel for performing  cluster analysis,
  and  J. Hetke and K. Wise for supplying silicon probes. The data used in this paper
  are available on request by e-mail to G. Buzsaki. This work was supported by National
  Institutes of Health Grants NS-34994,413 MH-54671, and MH-12403 (to D. A. Henze)
  and by the Epilepsy Foundationof America (to D. A. Henze).
article_processing_charge: No
article_type: original
author:
- first_name: Kenneth
  full_name: Harris, Kenneth
  last_name: Harris
- first_name: Darrell
  full_name: Henze, Darrell
  last_name: Henze
- first_name: Jozsef L
  full_name: Csicsvari, Jozsef L
  id: 3FA14672-F248-11E8-B48F-1D18A9856A87
  last_name: Csicsvari
  orcid: 0000-0002-5193-4036
- first_name: Hajima
  full_name: Hirase, Hajima
  last_name: Hirase
- first_name: György
  full_name: Buzsáki, György
  last_name: Buzsáki
citation:
  ama: Harris K, Henze D, Csicsvari JL, Hirase H, Buzsáki G. Accuracy of tetrode spike
    separation as determined by simultaneous intracellular and extracellular measurements.
    <i>Journal of Neurophysiology</i>. 2000;84(1):401-414. doi:<a href="https://doi.org/10.1152/jn.2000.84.1.401">10.1152/jn.2000.84.1.401</a>
  apa: Harris, K., Henze, D., Csicsvari, J. L., Hirase, H., &#38; Buzsáki, G. (2000).
    Accuracy of tetrode spike separation as determined by simultaneous intracellular
    and extracellular measurements. <i>Journal of Neurophysiology</i>. American Physiological
    Society. <a href="https://doi.org/10.1152/jn.2000.84.1.401">https://doi.org/10.1152/jn.2000.84.1.401</a>
  chicago: Harris, Kenneth, Darrell Henze, Jozsef L Csicsvari, Hajima Hirase, and
    György Buzsáki. “Accuracy of Tetrode Spike Separation as Determined by Simultaneous
    Intracellular and Extracellular Measurements.” <i>Journal of Neurophysiology</i>.
    American Physiological Society, 2000. <a href="https://doi.org/10.1152/jn.2000.84.1.401">https://doi.org/10.1152/jn.2000.84.1.401</a>.
  ieee: K. Harris, D. Henze, J. L. Csicsvari, H. Hirase, and G. Buzsáki, “Accuracy
    of tetrode spike separation as determined by simultaneous intracellular and extracellular
    measurements,” <i>Journal of Neurophysiology</i>, vol. 84, no. 1. American Physiological
    Society, pp. 401–414, 2000.
  ista: Harris K, Henze D, Csicsvari JL, Hirase H, Buzsáki G. 2000. Accuracy of tetrode
    spike separation as determined by simultaneous intracellular and extracellular
    measurements. Journal of Neurophysiology. 84(1), 401–414.
  mla: Harris, Kenneth, et al. “Accuracy of Tetrode Spike Separation as Determined
    by Simultaneous Intracellular and Extracellular Measurements.” <i>Journal of Neurophysiology</i>,
    vol. 84, no. 1, American Physiological Society, 2000, pp. 401–14, doi:<a href="https://doi.org/10.1152/jn.2000.84.1.401">10.1152/jn.2000.84.1.401</a>.
  short: K. Harris, D. Henze, J.L. Csicsvari, H. Hirase, G. Buzsáki, Journal of Neurophysiology
    84 (2000) 401–414.
date_created: 2018-12-11T12:03:54Z
date_published: 2000-07-01T00:00:00Z
date_updated: 2023-05-02T14:16:45Z
day: '01'
doi: 10.1152/jn.2000.84.1.401
extern: '1'
external_id:
  pmid:
  - '10899214 '
intvolume: '        84'
issue: '1'
language:
- iso: eng
month: '07'
oa_version: None
page: 401 - 414
pmid: 1
publication: Journal of Neurophysiology
publication_identifier:
  issn:
  - 0022-3077
publication_status: published
publisher: American Physiological Society
publist_id: '2837'
quality_controlled: '1'
status: public
title: Accuracy of tetrode spike separation as determined by simultaneous intracellular
  and extracellular measurements
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 84
year: '2000'
...
---
_id: '3555'
abstract:
- lang: eng
  text: A sliver is a tetrahedron whose four vertices lie close to a plane and whose
    perpendicular projection to that plane is a convex quadrilateral with no short
    edge. Slivers are both undesirable and ubiquitous in 3-dimensional Delaunay triangulations.
    Even when the point-set is well-spaced, slivers may result. This paper shows that
    such a point set permits a small perturbation whose Delaunay triangulation contains
    no slivers. It also gives deterministic algorithms that compute the perturbation
    of n points in time O(n log n) with one processor and in time O(log n) with O(n)
    processors.
article_processing_charge: No
author:
- first_name: Herbert
  full_name: Edelsbrunner, Herbert
  id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
  last_name: Edelsbrunner
  orcid: 0000-0002-9823-6833
- first_name: Xiang
  full_name: Li, Xiang
  id: 4B7E523C-F248-11E8-B48F-1D18A9856A87
  last_name: Li
- first_name: Gary
  full_name: Miller, Gary
  last_name: Miller
- first_name: Andreas
  full_name: Stathopoulos, Andreas
  last_name: Stathopoulos
- first_name: Dafna
  full_name: Talmor, Dafna
  last_name: Talmor
- first_name: Shang
  full_name: Teng, Shang
  last_name: Teng
- first_name: Alper
  full_name: Üngör, Alper
  last_name: Üngör
- first_name: Noel
  full_name: Walkington, Noel
  last_name: Walkington
citation:
  ama: 'Edelsbrunner H, Li X, Miller G, et al. Smoothing and cleaning up slivers.
    In: <i>Proceedings of the 32nd Annual ACM Symposium on Theory of Computing</i>.
    ACM; 2000:273-277. doi:<a href="https://doi.org/10.1145/335305.335338">10.1145/335305.335338</a>'
  apa: 'Edelsbrunner, H., Li, X., Miller, G., Stathopoulos, A., Talmor, D., Teng,
    S., … Walkington, N. (2000). Smoothing and cleaning up slivers. In <i>Proceedings
    of the 32nd annual ACM symposium on Theory of computing</i> (pp. 273–277). Portland,
    OR, USA: ACM. <a href="https://doi.org/10.1145/335305.335338">https://doi.org/10.1145/335305.335338</a>'
  chicago: Edelsbrunner, Herbert, Xiang Li, Gary Miller, Andreas Stathopoulos, Dafna
    Talmor, Shang Teng, Alper Üngör, and Noel Walkington. “Smoothing and Cleaning
    up Slivers.” In <i>Proceedings of the 32nd Annual ACM Symposium on Theory of Computing</i>,
    273–77. ACM, 2000. <a href="https://doi.org/10.1145/335305.335338">https://doi.org/10.1145/335305.335338</a>.
  ieee: H. Edelsbrunner <i>et al.</i>, “Smoothing and cleaning up slivers,” in <i>Proceedings
    of the 32nd annual ACM symposium on Theory of computing</i>, Portland, OR, USA,
    2000, pp. 273–277.
  ista: 'Edelsbrunner H, Li X, Miller G, Stathopoulos A, Talmor D, Teng S, Üngör A,
    Walkington N. 2000. Smoothing and cleaning up slivers. Proceedings of the 32nd
    annual ACM symposium on Theory of computing. STOC: Symposium on the Theory of
    Computing, 273–277.'
  mla: Edelsbrunner, Herbert, et al. “Smoothing and Cleaning up Slivers.” <i>Proceedings
    of the 32nd Annual ACM Symposium on Theory of Computing</i>, ACM, 2000, pp. 273–77,
    doi:<a href="https://doi.org/10.1145/335305.335338">10.1145/335305.335338</a>.
  short: H. Edelsbrunner, X. Li, G. Miller, A. Stathopoulos, D. Talmor, S. Teng, A.
    Üngör, N. Walkington, in:, Proceedings of the 32nd Annual ACM Symposium on Theory
    of Computing, ACM, 2000, pp. 273–277.
conference:
  end_date: 2000-05-23
  location: Portland, OR, USA
  name: 'STOC: Symposium on the Theory of Computing'
  start_date: 2000-05-21
date_created: 2018-12-11T12:03:56Z
date_published: 2000-06-01T00:00:00Z
date_updated: 2023-05-02T14:07:00Z
day: '01'
doi: 10.1145/335305.335338
extern: '1'
language:
- iso: eng
month: '06'
oa_version: None
page: 273 - 277
publication: Proceedings of the 32nd annual ACM symposium on Theory of computing
publication_identifier:
  isbn:
  - '9781581131840'
publication_status: published
publisher: ACM
publist_id: '2830'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Smoothing and cleaning up slivers
type: conference
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
year: '2000'
...
---
_id: '3572'
abstract:
- lang: eng
  text: "Allzulange wurde die spielhafte Beschäftigung als Gegensatz zu ernsthafter
    Arbeit gesehen. Dieser Artikel propagiert die spielerische Untersuchung von Kreis-
    und Kugelmengen. Gleichzeitig belegt er die nutzbare Anwendung\r\nvon elementaren
    Einsichten in der Molekularbiologie und allgemeiner\r\nin der Beschreibung von
    Form und Verformung."
article_processing_charge: No
author:
- first_name: Herbert
  full_name: Edelsbrunner, Herbert
  id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
  last_name: Edelsbrunner
  orcid: 0000-0002-9823-6833
citation:
  ama: 'Edelsbrunner H. Spielereien mit Kreisen und Kugeln. Zum Thema Form und Verformung.
    In: <i>Zur Kunst Des Formalen Denkens</i>. Passagen Verlag; 2000:153-171.'
  apa: Edelsbrunner, H. (2000). Spielereien mit Kreisen und Kugeln. Zum Thema Form
    und Verformung. In <i>Zur Kunst des formalen Denkens</i> (pp. 153–171). Passagen
    Verlag.
  chicago: Edelsbrunner, Herbert. “Spielereien Mit Kreisen Und Kugeln. Zum Thema Form
    Und Verformung.” In <i>Zur Kunst Des Formalen Denkens</i>, 153–71. Passagen Verlag,
    2000.
  ieee: H. Edelsbrunner, “Spielereien mit Kreisen und Kugeln. Zum Thema Form und Verformung,”
    in <i>Zur Kunst des formalen Denkens</i>, Passagen Verlag, 2000, pp. 153–171.
  ista: 'Edelsbrunner H. 2000.Spielereien mit Kreisen und Kugeln. Zum Thema Form und
    Verformung. In: Zur Kunst des formalen Denkens. , 153–171.'
  mla: Edelsbrunner, Herbert. “Spielereien Mit Kreisen Und Kugeln. Zum Thema Form
    Und Verformung.” <i>Zur Kunst Des Formalen Denkens</i>, Passagen Verlag, 2000,
    pp. 153–71.
  short: H. Edelsbrunner, in:, Zur Kunst Des Formalen Denkens, Passagen Verlag, 2000,
    pp. 153–171.
date_created: 2018-12-11T12:04:01Z
date_published: 2000-01-01T00:00:00Z
date_updated: 2023-05-02T13:07:14Z
day: '01'
extern: '1'
language:
- iso: eng
month: '01'
oa_version: None
page: 153 - 171
publication: Zur Kunst des formalen Denkens
publication_identifier:
  isbn:
  - '3851653580'
publication_status: published
publisher: Passagen Verlag
publist_id: '2813'
quality_controlled: '1'
status: public
title: Spielereien mit Kreisen und Kugeln. Zum Thema Form und Verformung
type: book_chapter
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
year: '2000'
...
---
_id: '3583'
abstract:
- lang: eng
  text: The Delaunay triangulation of a finite point set is a central theme in computational
    geometry. It finds its major application in the generation of meshes used in the
    simulation of physical processes. This paper connects the predominantly combinatorial
    work in classical computational geometry with the numerical interest in mesh generation.
    It focuses on the two- and three-dimensional case and covers results obtained
    during the twentieth century.
acknowledgement: Research is partially supported by the Army Research Office under
  grant DAAG55-98-1-0177 and by the National Science Foundation under grants CCR-96-19542
  and CCR-97-12088.
article_processing_charge: No
author:
- first_name: Herbert
  full_name: Edelsbrunner, Herbert
  id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
  last_name: Edelsbrunner
  orcid: 0000-0002-9823-6833
citation:
  ama: Edelsbrunner H. Triangulations and meshes in computational geometry. <i>Acta
    Numerica</i>. 2000;9:133-213. doi:<a href="https://doi.org/10.1017/S0962492900001331">10.1017/S0962492900001331</a>
  apa: Edelsbrunner, H. (2000). Triangulations and meshes in computational geometry.
    <i>Acta Numerica</i>. Cambridge University Press. <a href="https://doi.org/10.1017/S0962492900001331">https://doi.org/10.1017/S0962492900001331</a>
  chicago: Edelsbrunner, Herbert. “Triangulations and Meshes in Computational Geometry.”
    <i>Acta Numerica</i>. Cambridge University Press, 2000. <a href="https://doi.org/10.1017/S0962492900001331">https://doi.org/10.1017/S0962492900001331</a>.
  ieee: H. Edelsbrunner, “Triangulations and meshes in computational geometry,” <i>Acta
    Numerica</i>, vol. 9. Cambridge University Press, pp. 133–213, 2000.
  ista: Edelsbrunner H. 2000. Triangulations and meshes in computational geometry.
    Acta Numerica. 9, 133–213.
  mla: Edelsbrunner, Herbert. “Triangulations and Meshes in Computational Geometry.”
    <i>Acta Numerica</i>, vol. 9, Cambridge University Press, 2000, pp. 133–213, doi:<a
    href="https://doi.org/10.1017/S0962492900001331">10.1017/S0962492900001331</a>.
  short: H. Edelsbrunner, Acta Numerica 9 (2000) 133–213.
date_created: 2018-12-11T12:04:05Z
date_published: 2000-03-21T00:00:00Z
date_updated: 2023-05-02T12:20:27Z
day: '21'
doi: 10.1017/S0962492900001331
extern: '1'
intvolume: '         9'
language:
- iso: eng
month: '03'
oa_version: None
page: 133 - 213
publication: Acta Numerica
publication_status: published
publisher: Cambridge University Press
publist_id: '2802'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Triangulations and meshes in computational geometry
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 9
year: '2000'
...
---
_id: '3623'
abstract:
- lang: eng
  text: 'We present the theoretical background to a new method for measuring genetic
    variation for total fitness in Drosophila. The method allows heterozygous effects
    on total fitness of whole wild-type chromosomes to be measured under normal demography
    with overlapping generations. The wild-type chromosomes are competed against two
    balancer chromosomes (B1, B2, say), providing a standard genotype B1/B2 against
    which variation in the fitness effects of the wild-type chromosomes can be assessed.
    Fitness can be assessed in two ways: (i) at equilibrium of all three chromosomes
    under heterozygote advantage, and (ii) during displacement of one balancer by
    the other. Equilibrium with all three chromosomes present will be achieved only
    if the wild-type homozygote is not too fit, and if the fitnesses of the three
    heterozygotes are not too unequal. These conditions were not satisfied for any
    of a sample of 12 lethal-bearing chromosomes isolated from a random-bred laboratory
    population of Drosophila. At equilibrium, genotypic frequencies show low sensitivity
    to changes in genotypic fitness. Furthermore, where all four genotypes are viable
    and fertile, supplementary information from cages with only two chromosomes present
    and from direct measurements of pre-adult viability are required to estimate fitnesses
    from frequencies. The invasion method has the advantages of a greater sensitivity
    and of not requiring further data to estimate fitnesses if the wild-type homozygote
    is fertile. However, it requires that multiple samples be taken as the invasion
    progresses. In a discrete generation model, generation time influences fitness
    estimates from this method and is difficult to estimate accurately from the data.
    A full age-structured model can also be applied to the data from both types of
    experiment. For the invasion method, this gives fitness estimates close to those
    from the discrete generation model.'
acknowledgement: This work was supported by grant GR31/G09821 from the BBSRC, and
  by fellowships from the Darwin Trust of Edinburgh and the NERC. We are grateful
  to the referees for their helpful comments on the manuscript.
article_processing_charge: No
article_type: original
author:
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
- first_name: Linda
  full_name: Patridge, Linda
  last_name: Patridge
citation:
  ama: Barton NH, Patridge L. Measuring fitness by means of balancer chromosomes.
    <i>Genetical Research</i>. 2000;75(3):297-314. doi:<a href="https://doi.org/10.1017/S0016672399004346">10.1017/S0016672399004346</a>
  apa: Barton, N. H., &#38; Patridge, L. (2000). Measuring fitness by means of balancer
    chromosomes. <i>Genetical Research</i>. Cambridge University Press. <a href="https://doi.org/10.1017/S0016672399004346">https://doi.org/10.1017/S0016672399004346</a>
  chicago: Barton, Nicholas H, and Linda Patridge. “Measuring Fitness by Means of
    Balancer Chromosomes.” <i>Genetical Research</i>. Cambridge University Press,
    2000. <a href="https://doi.org/10.1017/S0016672399004346">https://doi.org/10.1017/S0016672399004346</a>.
  ieee: N. H. Barton and L. Patridge, “Measuring fitness by means of balancer chromosomes,”
    <i>Genetical Research</i>, vol. 75, no. 3. Cambridge University Press, pp. 297–314,
    2000.
  ista: Barton NH, Patridge L. 2000. Measuring fitness by means of balancer chromosomes.
    Genetical Research. 75(3), 297–314.
  mla: Barton, Nicholas H., and Linda Patridge. “Measuring Fitness by Means of Balancer
    Chromosomes.” <i>Genetical Research</i>, vol. 75, no. 3, Cambridge University
    Press, 2000, pp. 297–314, doi:<a href="https://doi.org/10.1017/S0016672399004346">10.1017/S0016672399004346</a>.
  short: N.H. Barton, L. Patridge, Genetical Research 75 (2000) 297–314.
date_created: 2018-12-11T12:04:18Z
date_published: 2000-06-01T00:00:00Z
date_updated: 2023-05-02T12:09:23Z
day: '01'
doi: 10.1017/S0016672399004346
extern: '1'
external_id:
  pmid:
  - '10893866'
intvolume: '        75'
issue: '3'
language:
- iso: eng
month: '06'
oa_version: None
page: 297 - 314
pmid: 1
publication: Genetical Research
publication_identifier:
  issn:
  - 0016-6723
publication_status: published
publisher: Cambridge University Press
publist_id: '2760'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Measuring fitness by means of balancer chromosomes
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 75
year: '2000'
...
---
_id: '3624'
abstract:
- lang: eng
  text: 'The state of a diploid population segregating for two alleles at each of
    n loci is described by 22(n) genotype frequencies, or equivalently, by allele
    frequencies and by multilocus moments or cumulants of various orders. These measures
    of linkage disequilibrium cannot usually be determined, both because one cannot
    tell whether a gene came from the maternal or paternal gamete, and because such
    a large number of parameters cannot be estimated even from large samples. Simplifying
    assumptions must therefore be made. This paper sets out methods for estimating
    multilocus genotype frequencies which are appropriate for unlinked neutral loci,
    and for populations that are ultimately derived by mixing of two source populations.
    In such a hybrid population, all multilocus associations depend primarily on the
    number of loci involved that derive from the maternal genome, and the number derived
    from the paternal genome Allele frequencies may differ across loci, and the contribution
    of each locus to multilocus associations may be scaled by the difference in allele
    frequency between source populations for that locus (δp ≤ 1). For example, the
    cumulant describing the association between genes i, j, k from the maternal genome,
    and genes i, l from the paternal genome is K(tJ,k,iλ*), = δp(i)/2 δp(J) δp(k)
    δp(l) κ3,2. The state of the population is described by n allele frequencies;
    n divergences, δp; and by a symmetric matrix of cumulants, κ(J,K) (J = 0 ,...,
    n, K = 0 ,..., n). Expressions for these cumulants under short- and long-range
    migration are given. Two methods for estimating the cumulants are described: a
    simple method based on multivariate moments, and a maximum likelihood procedure,
    which uses the Metropolis algorithm. Both methods perform well when tested against
    simulations with two or four loci.'
acknowledgement: This work was supported by grant MMI09726 from the BBSRC/EPSRC, and
  by the Darwin Trust of Edinburgh. I am grateful to W. G. Hill, L. Kruuk and M. Orive,
  and to the referees, for their helpful comments on the manuscript.
article_processing_charge: No
article_type: original
author:
- first_name: Nicholas H
  full_name: Barton, Nicholas H
  id: 4880FE40-F248-11E8-B48F-1D18A9856A87
  last_name: Barton
  orcid: 0000-0002-8548-5240
citation:
  ama: Barton NH. Estimating multilocus linkage disequilibria. <i>Heredity</i>. 2000;84(3):373-389.
    doi:<a href="https://doi.org/10.1046/j.1365-2540.2000.00683.x">10.1046/j.1365-2540.2000.00683.x</a>
  apa: Barton, N. H. (2000). Estimating multilocus linkage disequilibria. <i>Heredity</i>.
    Nature Publishing Group. <a href="https://doi.org/10.1046/j.1365-2540.2000.00683.x">https://doi.org/10.1046/j.1365-2540.2000.00683.x</a>
  chicago: Barton, Nicholas H. “Estimating Multilocus Linkage Disequilibria.” <i>Heredity</i>.
    Nature Publishing Group, 2000. <a href="https://doi.org/10.1046/j.1365-2540.2000.00683.x">https://doi.org/10.1046/j.1365-2540.2000.00683.x</a>.
  ieee: N. H. Barton, “Estimating multilocus linkage disequilibria,” <i>Heredity</i>,
    vol. 84, no. 3. Nature Publishing Group, pp. 373–389, 2000.
  ista: Barton NH. 2000. Estimating multilocus linkage disequilibria. Heredity. 84(3),
    373–389.
  mla: Barton, Nicholas H. “Estimating Multilocus Linkage Disequilibria.” <i>Heredity</i>,
    vol. 84, no. 3, Nature Publishing Group, 2000, pp. 373–89, doi:<a href="https://doi.org/10.1046/j.1365-2540.2000.00683.x">10.1046/j.1365-2540.2000.00683.x</a>.
  short: N.H. Barton, Heredity 84 (2000) 373–389.
date_created: 2018-12-11T12:04:18Z
date_published: 2000-03-01T00:00:00Z
date_updated: 2023-05-02T12:04:03Z
day: '01'
doi: 10.1046/j.1365-2540.2000.00683.x
extern: '1'
external_id:
  pmid:
  - '10762407'
intvolume: '        84'
issue: '3'
language:
- iso: eng
main_file_link:
- url: https://www.nature.com/articles/6886830
month: '03'
oa_version: None
page: 373 - 389
pmid: 1
publication: Heredity
publication_identifier:
  issn:
  - 0018-067X
publication_status: published
publisher: Nature Publishing Group
publist_id: '2759'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Estimating multilocus linkage disequilibria
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 84
year: '2000'
...
---
_id: '3798'
abstract:
- lang: eng
  text: Glutamate is the main excitatory transmitter in the mammalian CNS, mediating
    fast synaptic transmission primarily by activation of AMPA-type glutamate receptor
    channels. Both synaptic structure and a cell-specific molecular switch in the
    AMPA receptor subunit expression are involved in the regulation of the synaptic
    signaling time course.
acknowledgement: I thank Drs. J.R.P. Geiger,  K.  Haverkampf,  and  B.  Taskin  for  helpful
  discussions.  This review is based on a lecture  given in Lisbon in March 1998 on
  the occasion of the first award of the Medinfar European Prize in Physiology. My
  studies are supported by the Deutsche Forschungsgemeinschaft, the German Israeli
  Foundation, and the Human Frontiers Science Program Organization. I regret that
  many relevant papers could not be cited due to editorial restric-tions on the maximum
  number of references.
article_processing_charge: No
article_type: original
author:
- first_name: Peter M
  full_name: Jonas, Peter M
  id: 353C1B58-F248-11E8-B48F-1D18A9856A87
  last_name: Jonas
  orcid: 0000-0001-5001-4804
citation:
  ama: Jonas PM. The time course of signaling at central glutamatergic synapses. <i>Physiology</i>.
    2000;15(2):83-89. doi:<a href="https://doi.org/10.1152/physiologyonline.2000.15.2.83">10.1152/physiologyonline.2000.15.2.83</a>
  apa: Jonas, P. M. (2000). The time course of signaling at central glutamatergic
    synapses. <i>Physiology</i>. American Physiological Society. <a href="https://doi.org/10.1152/physiologyonline.2000.15.2.83">https://doi.org/10.1152/physiologyonline.2000.15.2.83</a>
  chicago: Jonas, Peter M. “The Time Course of Signaling at Central Glutamatergic
    Synapses.” <i>Physiology</i>. American Physiological Society, 2000. <a href="https://doi.org/10.1152/physiologyonline.2000.15.2.83">https://doi.org/10.1152/physiologyonline.2000.15.2.83</a>.
  ieee: P. M. Jonas, “The time course of signaling at central glutamatergic synapses,”
    <i>Physiology</i>, vol. 15, no. 2. American Physiological Society, pp. 83–89,
    2000.
  ista: Jonas PM. 2000. The time course of signaling at central glutamatergic synapses.
    Physiology. 15(2), 83–89.
  mla: Jonas, Peter M. “The Time Course of Signaling at Central Glutamatergic Synapses.”
    <i>Physiology</i>, vol. 15, no. 2, American Physiological Society, 2000, pp. 83–89,
    doi:<a href="https://doi.org/10.1152/physiologyonline.2000.15.2.83">10.1152/physiologyonline.2000.15.2.83</a>.
  short: P.M. Jonas, Physiology 15 (2000) 83–89.
date_created: 2018-12-11T12:05:14Z
date_published: 2000-04-01T00:00:00Z
date_updated: 2023-05-02T11:57:50Z
day: '01'
doi: 10.1152/physiologyonline.2000.15.2.83
extern: '1'
external_id:
  pmid:
  - '11390884'
intvolume: '        15'
issue: '2'
language:
- iso: eng
month: '04'
oa_version: None
page: 83 - 89
pmid: 1
publication: Physiology
publication_identifier:
  issn:
  - 1548-9213
publication_status: published
publisher: American Physiological Society
publist_id: '2412'
quality_controlled: '1'
scopus_import: '1'
status: public
title: The time course of signaling at central glutamatergic synapses
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 15
year: '2000'
...
---
_id: '3923'
article_processing_charge: No
author:
- first_name: Sylvia
  full_name: Cremer, Sylvia
  id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
  last_name: Cremer
  orcid: 0000-0002-2193-3868
citation:
  ama: 'Cremer S. Paternity analysis with AFLPs in Cardiocondyla ants. <i>Futura:
    the Journal of the Boehringer Ingelheim Fonds</i>. 2000;15(1):68-71.'
  apa: 'Cremer, S. (2000). Paternity analysis with AFLPs in Cardiocondyla ants. <i>Futura:
    The Journal of the Boehringer Ingelheim Fonds</i>. Hippokrates.'
  chicago: 'Cremer, Sylvia. “Paternity Analysis with AFLPs in Cardiocondyla Ants.”
    <i>Futura: The Journal of the Boehringer Ingelheim Fonds</i>. Hippokrates, 2000.'
  ieee: 'S. Cremer, “Paternity analysis with AFLPs in Cardiocondyla ants,” <i>Futura:
    the Journal of the Boehringer Ingelheim Fonds</i>, vol. 15, no. 1. Hippokrates,
    pp. 68–71, 2000.'
  ista: 'Cremer S. 2000. Paternity analysis with AFLPs in Cardiocondyla ants. Futura:
    the Journal of the Boehringer Ingelheim Fonds. 15(1), 68–71.'
  mla: 'Cremer, Sylvia. “Paternity Analysis with AFLPs in Cardiocondyla Ants.” <i>Futura:
    The Journal of the Boehringer Ingelheim Fonds</i>, vol. 15, no. 1, Hippokrates,
    2000, pp. 68–71.'
  short: 'S. Cremer, Futura: The Journal of the Boehringer Ingelheim Fonds 15 (2000)
    68–71.'
date_created: 2018-12-11T12:05:55Z
date_published: 2000-01-01T00:00:00Z
date_updated: 2023-05-02T11:47:47Z
day: '01'
extern: '1'
intvolume: '        15'
issue: '1'
language:
- iso: eng
month: '01'
oa_version: None
page: 68 - 71
publication: 'Futura: the Journal of the Boehringer Ingelheim Fonds'
publication_identifier:
  issn:
  - 0179-6372
publication_status: published
publisher: Hippokrates
publist_id: '2228'
status: public
title: Paternity analysis with AFLPs in Cardiocondyla ants
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 15
year: '2000'
...
---
_id: '4004'
abstract:
- lang: eng
  text: In this paper we introduce the abacus model of a simplex and use it to subdivide
    a d-simplex into k(d) d-simplices all of the same volume and shape characteristics.
    The construction is an extension of the subdivision method of Freudenthal [3]
    and has been used by Goodman and Peters [4] to design smooth manifolds.
acknowledgement: NSF under Grant DMS 98-73945, NSF under Grant CCR-96-19542 and by
  ARO under Grant DAAG55- 98-1-0177.
article_processing_charge: No
article_type: original
author:
- first_name: Herbert
  full_name: Edelsbrunner, Herbert
  id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
  last_name: Edelsbrunner
  orcid: 0000-0002-9823-6833
- first_name: Daniel
  full_name: Grayson, Daniel
  last_name: Grayson
citation:
  ama: Edelsbrunner H, Grayson D. Edgewise subdivision of a simplex. <i>Discrete &#38;
    Computational Geometry</i>. 2000;24(4):707-719. doi:<a href="https://doi.org/10.1007/s004540010063">10.1007/s004540010063</a>
  apa: Edelsbrunner, H., &#38; Grayson, D. (2000). Edgewise subdivision of a simplex.
    <i>Discrete &#38; Computational Geometry</i>. Springer. <a href="https://doi.org/10.1007/s004540010063">https://doi.org/10.1007/s004540010063</a>
  chicago: Edelsbrunner, Herbert, and Daniel Grayson. “Edgewise Subdivision of a Simplex.”
    <i>Discrete &#38; Computational Geometry</i>. Springer, 2000. <a href="https://doi.org/10.1007/s004540010063">https://doi.org/10.1007/s004540010063</a>.
  ieee: H. Edelsbrunner and D. Grayson, “Edgewise subdivision of a simplex,” <i>Discrete
    &#38; Computational Geometry</i>, vol. 24, no. 4. Springer, pp. 707–719, 2000.
  ista: Edelsbrunner H, Grayson D. 2000. Edgewise subdivision of a simplex. Discrete
    &#38; Computational Geometry. 24(4), 707–719.
  mla: Edelsbrunner, Herbert, and Daniel Grayson. “Edgewise Subdivision of a Simplex.”
    <i>Discrete &#38; Computational Geometry</i>, vol. 24, no. 4, Springer, 2000,
    pp. 707–19, doi:<a href="https://doi.org/10.1007/s004540010063">10.1007/s004540010063</a>.
  short: H. Edelsbrunner, D. Grayson, Discrete &#38; Computational Geometry 24 (2000)
    707–719.
date_created: 2018-12-11T12:06:23Z
date_published: 2000-12-01T00:00:00Z
date_updated: 2023-05-02T11:43:59Z
day: '01'
doi: 10.1007/s004540010063
extern: '1'
intvolume: '        24'
issue: '4'
language:
- iso: eng
month: '12'
oa_version: None
page: 707 - 719
publication: Discrete & Computational Geometry
publication_identifier:
  issn:
  - 0179-5376
publication_status: published
publisher: Springer
publist_id: '2119'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Edgewise subdivision of a simplex
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 24
year: '2000'
...
---
_id: '4008'
abstract:
- lang: eng
  text: We formalize a notion of topological simplification within the framework of
    a filtration, which is the history of a growing complex. We classify a topological
    change that happens during growth as either a feature or noise depending on its
    life-time or persistence within the filtration. We give fast algorithms for computing
    persistence and experimental evidence for their speed and utility.
acknowledgement: Research by the first and third authors is partially supported by
  ARO under grant DAAG55-98-1-0177. Research by the first author is also partially
  supported by NSF under grant CCR-97-12088.
article_processing_charge: No
author:
- first_name: Herbert
  full_name: Edelsbrunner, Herbert
  id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
  last_name: Edelsbrunner
  orcid: 0000-0002-9823-6833
- first_name: David
  full_name: Letscher, David
  last_name: Letscher
- first_name: Afra
  full_name: Zomorodian, Afra
  last_name: Zomorodian
citation:
  ama: 'Edelsbrunner H, Letscher D, Zomorodian A. Topological persistance and simplification.
    In: <i>Proceedings 41st Annual Symposium on Foundations of Computer Science</i>.
    IEEE; 2000:454-463. doi:<a href="https://doi.org/10.1109/SFCS.2000.892133">10.1109/SFCS.2000.892133</a>'
  apa: 'Edelsbrunner, H., Letscher, D., &#38; Zomorodian, A. (2000). Topological persistance
    and simplification. In <i>Proceedings 41st Annual Symposium on Foundations of
    Computer Science</i> (pp. 454–463). Washington, DC, United States: IEEE. <a href="https://doi.org/10.1109/SFCS.2000.892133">https://doi.org/10.1109/SFCS.2000.892133</a>'
  chicago: Edelsbrunner, Herbert, David Letscher, and Afra Zomorodian. “Topological
    Persistance and Simplification.” In <i>Proceedings 41st Annual Symposium on Foundations
    of Computer Science</i>, 454–63. IEEE, 2000. <a href="https://doi.org/10.1109/SFCS.2000.892133">https://doi.org/10.1109/SFCS.2000.892133</a>.
  ieee: H. Edelsbrunner, D. Letscher, and A. Zomorodian, “Topological persistance
    and simplification,” in <i>Proceedings 41st Annual Symposium on Foundations of
    Computer Science</i>, Washington, DC, United States, 2000, pp. 454–463.
  ista: 'Edelsbrunner H, Letscher D, Zomorodian A. 2000. Topological persistance and
    simplification. Proceedings 41st Annual Symposium on Foundations of Computer Science.
    FOCS: Foundations of Computer Science, 454–463.'
  mla: Edelsbrunner, Herbert, et al. “Topological Persistance and Simplification.”
    <i>Proceedings 41st Annual Symposium on Foundations of Computer Science</i>, IEEE,
    2000, pp. 454–63, doi:<a href="https://doi.org/10.1109/SFCS.2000.892133">10.1109/SFCS.2000.892133</a>.
  short: H. Edelsbrunner, D. Letscher, A. Zomorodian, in:, Proceedings 41st Annual
    Symposium on Foundations of Computer Science, IEEE, 2000, pp. 454–463.
conference:
  end_date: 2000-11-14
  location: Washington, DC, United States
  name: 'FOCS: Foundations of Computer Science'
  start_date: 2000-11-12
date_created: 2018-12-11T12:06:24Z
date_published: 2000-11-01T00:00:00Z
date_updated: 2023-04-25T06:53:21Z
day: '01'
doi: 10.1109/SFCS.2000.892133
extern: '1'
language:
- iso: eng
month: '11'
oa_version: None
page: 454 - 463
publication: Proceedings 41st Annual Symposium on Foundations of Computer Science
publication_identifier:
  isbn:
  - '0769508502'
publication_status: published
publisher: IEEE
publist_id: '2116'
quality_controlled: '1'
status: public
title: Topological persistance and simplification
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2000'
...
---
_id: '4009'
abstract:
- lang: eng
  text: We study the maintenance of a simplicial grid or complex under changing density
    requirements. The proposed method works in any fixed dimension and generates grids
    by projecting cross-sections of a monotone simplicial complex that lives in one
    dimension higher than the grid. The density of the grid is adapted by locally
    moving the cross-section up or down along the extra dimension.
article_processing_charge: No
article_type: original
author:
- first_name: Herbert
  full_name: Edelsbrunner, Herbert
  id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
  last_name: Edelsbrunner
  orcid: 0000-0002-9823-6833
- first_name: Roman
  full_name: Waupotitsch, Roman
  last_name: Waupotitsch
citation:
  ama: Edelsbrunner H, Waupotitsch R. Adaptive simplicial grids from cross-sections
    of monotone complexes. <i>International Journal of Computational Geometry and
    Applications</i>. 2000;10(3):267-284. doi:<a href="https://doi.org/10.1142/S0218195900000164">10.1142/S0218195900000164</a>
  apa: Edelsbrunner, H., &#38; Waupotitsch, R. (2000). Adaptive simplicial grids from
    cross-sections of monotone complexes. <i>International Journal of Computational
    Geometry and Applications</i>. World Scientific Publishing. <a href="https://doi.org/10.1142/S0218195900000164">https://doi.org/10.1142/S0218195900000164</a>
  chicago: Edelsbrunner, Herbert, and Roman Waupotitsch. “Adaptive Simplicial Grids
    from Cross-Sections of Monotone Complexes.” <i>International Journal of Computational
    Geometry and Applications</i>. World Scientific Publishing, 2000. <a href="https://doi.org/10.1142/S0218195900000164">https://doi.org/10.1142/S0218195900000164</a>.
  ieee: H. Edelsbrunner and R. Waupotitsch, “Adaptive simplicial grids from cross-sections
    of monotone complexes,” <i>International Journal of Computational Geometry and
    Applications</i>, vol. 10, no. 3. World Scientific Publishing, pp. 267–284, 2000.
  ista: Edelsbrunner H, Waupotitsch R. 2000. Adaptive simplicial grids from cross-sections
    of monotone complexes. International Journal of Computational Geometry and Applications.
    10(3), 267–284.
  mla: Edelsbrunner, Herbert, and Roman Waupotitsch. “Adaptive Simplicial Grids from
    Cross-Sections of Monotone Complexes.” <i>International Journal of Computational
    Geometry and Applications</i>, vol. 10, no. 3, World Scientific Publishing, 2000,
    pp. 267–84, doi:<a href="https://doi.org/10.1142/S0218195900000164">10.1142/S0218195900000164</a>.
  short: H. Edelsbrunner, R. Waupotitsch, International Journal of Computational Geometry
    and Applications 10 (2000) 267–284.
date_created: 2018-12-11T12:06:25Z
date_published: 2000-06-01T00:00:00Z
date_updated: 2023-04-20T13:45:46Z
day: '01'
doi: 10.1142/S0218195900000164
extern: '1'
intvolume: '        10'
issue: '3'
language:
- iso: eng
month: '06'
oa_version: None
page: 267 - 284
publication: International Journal of Computational Geometry and Applications
publication_identifier:
  issn:
  - 0218-1959
publication_status: published
publisher: World Scientific Publishing
publist_id: '2117'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Adaptive simplicial grids from cross-sections of monotone complexes
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 10
year: '2000'
...
---
_id: '4010'
abstract:
- lang: eng
  text: A sliver is a tetrahedron whose four vertices lie close to a plane and whose
    orthogonal projection to that plane is a convex quadrilateral with no short edge.
    Slivers are notoriously common in 3-dimensional Delaunay triangulations even for
    well-spaced point sets. We show that, if the Delaunay triangulation has the ratio
    property introduced in Miller et al. [1995], then there is an assignment of weights
    so the weighted Delaunay triangulation contains no slivers. We also give an algorithm
    to compute such a weight assignment.
acknowledgement: NSF under grant DMS 98-73945, NSF under grant CCR 96-19542 and ARO
  under grant DAAG-55-98-1-0177.
article_processing_charge: No
article_type: original
author:
- first_name: Siu
  full_name: Cheng, Siu
  last_name: Cheng
- first_name: Tamal
  full_name: Dey, Tamal
  last_name: Dey
- first_name: Herbert
  full_name: Edelsbrunner, Herbert
  id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
  last_name: Edelsbrunner
  orcid: 0000-0002-9823-6833
- first_name: Michael
  full_name: Facello, Michael
  last_name: Facello
- first_name: Shang
  full_name: Teng, Shang
  last_name: Teng
citation:
  ama: Cheng S, Dey T, Edelsbrunner H, Facello M, Teng S. Sliver exudation. <i>Journal
    of the ACM</i>. 2000;47(5):883-904. doi:<a href="https://doi.org/10.1145/355483.355487">10.1145/355483.355487</a>
  apa: Cheng, S., Dey, T., Edelsbrunner, H., Facello, M., &#38; Teng, S. (2000). Sliver
    exudation. <i>Journal of the ACM</i>. ACM. <a href="https://doi.org/10.1145/355483.355487">https://doi.org/10.1145/355483.355487</a>
  chicago: Cheng, Siu, Tamal Dey, Herbert Edelsbrunner, Michael Facello, and Shang
    Teng. “Sliver Exudation.” <i>Journal of the ACM</i>. ACM, 2000. <a href="https://doi.org/10.1145/355483.355487">https://doi.org/10.1145/355483.355487</a>.
  ieee: S. Cheng, T. Dey, H. Edelsbrunner, M. Facello, and S. Teng, “Sliver exudation,”
    <i>Journal of the ACM</i>, vol. 47, no. 5. ACM, pp. 883–904, 2000.
  ista: Cheng S, Dey T, Edelsbrunner H, Facello M, Teng S. 2000. Sliver exudation.
    Journal of the ACM. 47(5), 883–904.
  mla: Cheng, Siu, et al. “Sliver Exudation.” <i>Journal of the ACM</i>, vol. 47,
    no. 5, ACM, 2000, pp. 883–904, doi:<a href="https://doi.org/10.1145/355483.355487">10.1145/355483.355487</a>.
  short: S. Cheng, T. Dey, H. Edelsbrunner, M. Facello, S. Teng, Journal of the ACM
    47 (2000) 883–904.
date_created: 2018-12-11T12:06:25Z
date_published: 2000-09-01T00:00:00Z
date_updated: 2023-04-21T08:58:30Z
day: '01'
doi: 10.1145/355483.355487
extern: '1'
intvolume: '        47'
issue: '5'
language:
- iso: eng
month: '09'
oa_version: None
page: 883 - 904
publication: Journal of the ACM
publication_identifier:
  issn:
  - 0004-5411
publication_status: published
publisher: ACM
publist_id: '2118'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Sliver exudation
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 47
year: '2000'
...
