---
_id: '2709'
article_processing_charge: No
author:
- first_name: László
  full_name: Erdös, László
  id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
  last_name: Erdös
  orcid: 0000-0001-5366-9603
citation:
  ama: 'Erdös L. Long time dynamics of an electron in a weakly coupled phonon field.
    In: <i>13th International Congress of Mathematical Physics</i>.  International
    Press of Boston; 2001:273-281.'
  apa: Erdös, L. (2001). Long time dynamics of an electron in a weakly coupled phonon
    field. In <i>13th International Congress of Mathematical Physics</i> (pp. 273–281).  International
    Press of Boston.
  chicago: Erdös, László. “Long Time Dynamics of an Electron in a Weakly Coupled Phonon
    Field.” In <i>13th International Congress of Mathematical Physics</i>, 273–81.  International
    Press of Boston, 2001.
  ieee: L. Erdös, “Long time dynamics of an electron in a weakly coupled phonon field,”
    in <i>13th International Congress of Mathematical Physics</i>,  International
    Press of Boston, 2001, pp. 273–281.
  ista: 'Erdös L. 2001.Long time dynamics of an electron in a weakly coupled phonon
    field. In: 13th International Congress of Mathematical Physics. , 273–281.'
  mla: Erdös, László. “Long Time Dynamics of an Electron in a Weakly Coupled Phonon
    Field.” <i>13th International Congress of Mathematical Physics</i>,  International
    Press of Boston, 2001, pp. 273–81.
  short: L. Erdös, in:, 13th International Congress of Mathematical Physics,  International
    Press of Boston, 2001, pp. 273–281.
date_created: 2018-12-11T11:59:11Z
date_published: 2001-01-01T00:00:00Z
date_updated: 2023-05-22T12:11:29Z
day: '01'
extern: '1'
language:
- iso: eng
month: '01'
oa_version: None
page: 273 - 281
publication: 13th International Congress of Mathematical Physics
publication_identifier:
  isbn:
  - '9781571460851'
publication_status: published
publisher: ' International Press of Boston'
publist_id: '4187'
quality_controlled: '1'
status: public
title: Long time dynamics of an electron in a weakly coupled phonon field
type: book_chapter
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
year: '2001'
...
---
_id: '2734'
abstract:
- lang: eng
  text: In this paper we describe an intrinsically geometric way of producing magnetic
    fields on S3 and R3 for which the corresponding Dirac operators have a non-trivial
    kernel. In many cases we are able to compute the dimension of the kernel. In particular
    we can give examples where the kernel has any given dimension. This generalizes
    the examples of Loss and Yau [1].
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: László
  full_name: Erdös, László
  id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
  last_name: Erdös
  orcid: 0000-0001-5366-9603
- first_name: Jan
  full_name: Solovej, Jan
  last_name: Solovej
citation:
  ama: Erdös L, Solovej J. The kernel of Dirac operators on S3 and R3. <i>Reviews
    in Mathematical Physics</i>. 2001;13(10):1247-1280. doi:<a href="https://doi.org/10.1142/S0129055X01000983">10.1142/S0129055X01000983</a>
  apa: Erdös, L., &#38; Solovej, J. (2001). The kernel of Dirac operators on S3 and
    R3. <i>Reviews in Mathematical Physics</i>. World Scientific Publishing. <a href="https://doi.org/10.1142/S0129055X01000983">https://doi.org/10.1142/S0129055X01000983</a>
  chicago: Erdös, László, and Jan Solovej. “The Kernel of Dirac Operators on S3 and
    R3.” <i>Reviews in Mathematical Physics</i>. World Scientific Publishing, 2001.
    <a href="https://doi.org/10.1142/S0129055X01000983">https://doi.org/10.1142/S0129055X01000983</a>.
  ieee: L. Erdös and J. Solovej, “The kernel of Dirac operators on S3 and R3,” <i>Reviews
    in Mathematical Physics</i>, vol. 13, no. 10. World Scientific Publishing, pp.
    1247–1280, 2001.
  ista: Erdös L, Solovej J. 2001. The kernel of Dirac operators on S3 and R3. Reviews
    in Mathematical Physics. 13(10), 1247–1280.
  mla: Erdös, László, and Jan Solovej. “The Kernel of Dirac Operators on S3 and R3.”
    <i>Reviews in Mathematical Physics</i>, vol. 13, no. 10, World Scientific Publishing,
    2001, pp. 1247–80, doi:<a href="https://doi.org/10.1142/S0129055X01000983">10.1142/S0129055X01000983</a>.
  short: L. Erdös, J. Solovej, Reviews in Mathematical Physics 13 (2001) 1247–1280.
date_created: 2018-12-11T11:59:19Z
date_published: 2001-10-01T00:00:00Z
date_updated: 2023-05-16T12:24:25Z
day: '01'
doi: 10.1142/S0129055X01000983
extern: '1'
external_id:
  arxiv:
  - math-ph/0001036
intvolume: '        13'
issue: '10'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/math-ph/0001036
month: '10'
oa: 1
oa_version: Published Version
page: 1247 - 1280
publication: Reviews in Mathematical Physics
publication_identifier:
  issn:
  - 0129-055X
publication_status: published
publisher: World Scientific Publishing
publist_id: '4158'
quality_controlled: '1'
scopus_import: '1'
status: public
title: The kernel of Dirac operators on S3 and R3
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 13
year: '2001'
...
---
_id: '2735'
abstract:
- lang: eng
  text: We establish the exact low-energy asymptotics of the integrated density of
    states (Lifschitz tail) in a homogeneous magnetic field and Poissonian impurities
    with a repulsive single-site potential of Gaussian decay. It has been known that
    the Gaussian potential tail discriminates between the so-called “classical” and
    “quantum” regimes, and precise asymptotics are known in these cases. For the borderline
    case, the coexistence of the classical and quantum regimes was conjectured. Here
    we settle this last remaining open case to complete the full picture of the magnetic
    Lifschitz tails.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: László
  full_name: Erdös, László
  id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
  last_name: Erdös
  orcid: 0000-0001-5366-9603
citation:
  ama: 'Erdös L. Lifschitz tail in a magnetic field: Coexistence of classical and
    quantum behavior in the borderline case. <i>Probability Theory and Related Fields</i>.
    2001;121(2):219-236. doi:<a href="https://doi.org/10.1007/PL00008803">10.1007/PL00008803</a>'
  apa: 'Erdös, L. (2001). Lifschitz tail in a magnetic field: Coexistence of classical
    and quantum behavior in the borderline case. <i>Probability Theory and Related
    Fields</i>. Springer. <a href="https://doi.org/10.1007/PL00008803">https://doi.org/10.1007/PL00008803</a>'
  chicago: 'Erdös, László. “Lifschitz Tail in a Magnetic Field: Coexistence of Classical
    and Quantum Behavior in the Borderline Case.” <i>Probability Theory and Related
    Fields</i>. Springer, 2001. <a href="https://doi.org/10.1007/PL00008803">https://doi.org/10.1007/PL00008803</a>.'
  ieee: 'L. Erdös, “Lifschitz tail in a magnetic field: Coexistence of classical and
    quantum behavior in the borderline case,” <i>Probability Theory and Related Fields</i>,
    vol. 121, no. 2. Springer, pp. 219–236, 2001.'
  ista: 'Erdös L. 2001. Lifschitz tail in a magnetic field: Coexistence of classical
    and quantum behavior in the borderline case. Probability Theory and Related Fields.
    121(2), 219–236.'
  mla: 'Erdös, László. “Lifschitz Tail in a Magnetic Field: Coexistence of Classical
    and Quantum Behavior in the Borderline Case.” <i>Probability Theory and Related
    Fields</i>, vol. 121, no. 2, Springer, 2001, pp. 219–36, doi:<a href="https://doi.org/10.1007/PL00008803">10.1007/PL00008803</a>.'
  short: L. Erdös, Probability Theory and Related Fields 121 (2001) 219–236.
date_created: 2018-12-11T11:59:19Z
date_published: 2001-10-01T00:00:00Z
date_updated: 2023-05-16T12:20:42Z
day: '01'
doi: 10.1007/PL00008803
extern: '1'
external_id:
  arxiv:
  - math-ph/0003023
intvolume: '       121'
issue: '2'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://arxiv.org/abs/math-ph/0003023
month: '10'
oa: 1
oa_version: Published Version
page: 219 - 236
publication: Probability Theory and Related Fields
publication_identifier:
  issn:
  - 0044-3719
publication_status: published
publisher: Springer
publist_id: '4157'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Lifschitz tail in a magnetic field: Coexistence of classical and quantum behavior
  in the borderline case'
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 121
year: '2001'
...
---
_id: '2736'
abstract:
- lang: eng
  text: We consider the time evolution of N bosonic particles interacting via a mean
    field Coulomb potential. Suppose the initial state is a product wavefunction.
    We show that at any finite time the correlation functions factorize in the limit
    N → ∞. Furthermore, the limiting one particle density matrix satisfies the nonlinear
    Hartree equation. The key ingredients are the uniqueness of the BBGKY hierarchy
    for the correlation functions and a new apriori estimate for the many-body Schrödinger
    equations.
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: László
  full_name: Erdös, László
  id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
  last_name: Erdös
  orcid: 0000-0001-5366-9603
- first_name: Horng
  full_name: Yau, Horng
  last_name: Yau
citation:
  ama: Erdös L, Yau H. Derivation of the nonlinear Schrödinger equation from a many
    body Coulomb system. <i>Advances in Theoretical and Mathematical Physics</i>.
    2001;5(6):1169-1205. doi:<a href="https://doi.org/10.48550/arXiv.math-ph/0111042">10.48550/arXiv.math-ph/0111042</a>
  apa: Erdös, L., &#38; Yau, H. (2001). Derivation of the nonlinear Schrödinger equation
    from a many body Coulomb system. <i>Advances in Theoretical and Mathematical Physics</i>.
    International Press. <a href="https://doi.org/10.48550/arXiv.math-ph/0111042">https://doi.org/10.48550/arXiv.math-ph/0111042</a>
  chicago: Erdös, László, and Horng Yau. “Derivation of the Nonlinear Schrödinger
    Equation from a Many Body Coulomb System.” <i>Advances in Theoretical and Mathematical
    Physics</i>. International Press, 2001. <a href="https://doi.org/10.48550/arXiv.math-ph/0111042">https://doi.org/10.48550/arXiv.math-ph/0111042</a>.
  ieee: L. Erdös and H. Yau, “Derivation of the nonlinear Schrödinger equation from
    a many body Coulomb system,” <i>Advances in Theoretical and Mathematical Physics</i>,
    vol. 5, no. 6. International Press, pp. 1169–1205, 2001.
  ista: Erdös L, Yau H. 2001. Derivation of the nonlinear Schrödinger equation from
    a many body Coulomb system. Advances in Theoretical and Mathematical Physics.
    5(6), 1169–1205.
  mla: Erdös, László, and Horng Yau. “Derivation of the Nonlinear Schrödinger Equation
    from a Many Body Coulomb System.” <i>Advances in Theoretical and Mathematical
    Physics</i>, vol. 5, no. 6, International Press, 2001, pp. 1169–205, doi:<a href="https://doi.org/10.48550/arXiv.math-ph/0111042">10.48550/arXiv.math-ph/0111042</a>.
  short: L. Erdös, H. Yau, Advances in Theoretical and Mathematical Physics 5 (2001)
    1169–1205.
date_created: 2018-12-11T11:59:20Z
date_published: 2001-11-01T00:00:00Z
date_updated: 2023-05-16T12:12:41Z
day: '01'
doi: 10.48550/arXiv.math-ph/0111042
extern: '1'
external_id:
  arxiv:
  - math-ph/0111042
intvolume: '         5'
issue: '6'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: http://arxiv.org/abs/math-ph/0111042
month: '11'
oa: 1
oa_version: Published Version
page: 1169 - 1205
publication: Advances in Theoretical and Mathematical Physics
publication_identifier:
  issn:
  - 1095-0761
publication_status: published
publisher: International Press
publist_id: '4156'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Derivation of the nonlinear Schrödinger equation from a many body Coulomb system
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 5
year: '2001'
...
---
_id: '2981'
abstract:
- lang: eng
  text: Plants contain a novel unique subfamily of Rho GTPases, vital components of
    cellular signalling networks. Here we report a general role for some members of
    this family in polarized plant growth processes. We show that Arabidopsis AtRop4
    and AtRop6 encode functional GTPases with similar intrinsic GTP hydrolysis rates.
    We localized AtRop proteins in root meristem cells to the cross-wall and cell
    plate membranes. Polar localization of AtRops in trichoblasts specifies the growth
    sites for emerging root hairs. These sites were visible before budding and elongation
    of the Arabidopsis root hair when AtRops accumulated at their tips. Expression
    of constitutively active AtRop4 and AtRop6 mutant proteins in root hairs of transgenic
    Arabidopsis plants abolished polarized growth and delocalized the tip-focused
    Ca2+ gradient. Polar localization of AtRops was inhibited by brefeldin A, but
    not by other drugs such as latrunculin B, cytochalasin D or caffeine. Our results
    demonstrate a general function of AtRop GTPases in tip growth and in polar diffuse
    growth.
acknowledgement: We thank Drs Frantisek Baluška, Matthias Godde, Peter Huijser, Lars
  Vahlkamp and Dieter Volkmann for help, criticism and constructive reading of the
  manuscript. We are grateful to Dr N.-H.Chua for providing us with pTA7002. The work
  was funded by the DFG, the European Communities Biotechnology Programme (Bio4-CT98
  0239) and the INCO Copernicus Programme (IC15-CT96-0920). C.S.V.R. is the recipient
  of an Alexander von Humboldt fellowship and J.F. of a DAAD fellowship.
article_processing_charge: No
article_type: original
author:
- first_name: Arthur
  full_name: Molendijk, Arthur
  last_name: Molendijk
- first_name: Friedrich
  full_name: Bischoff, Friedrich
  last_name: Bischoff
- first_name: Chadalavada
  full_name: Rajendrakumar, Chadalavada
  last_name: Rajendrakumar
- first_name: Jirí
  full_name: Friml, Jirí
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
- first_name: Markus
  full_name: Braun, Markus
  last_name: Braun
- first_name: Simon
  full_name: Gilroy, Simon
  last_name: Gilroy
- first_name: Klaus
  full_name: Palme, Klaus
  last_name: Palme
citation:
  ama: Molendijk A, Bischoff F, Rajendrakumar C, et al. Arabidopsis thaliana Rop GTPases
    are localized to tips of root hairs and control polar growth. <i>EMBO Journal</i>.
    2001;20(11):2779-2788. doi:<a href="https://doi.org/10.1093/emboj/20.11.2779">10.1093/emboj/20.11.2779</a>
  apa: Molendijk, A., Bischoff, F., Rajendrakumar, C., Friml, J., Braun, M., Gilroy,
    S., &#38; Palme, K. (2001). Arabidopsis thaliana Rop GTPases are localized to
    tips of root hairs and control polar growth. <i>EMBO Journal</i>. Wiley-Blackwell.
    <a href="https://doi.org/10.1093/emboj/20.11.2779">https://doi.org/10.1093/emboj/20.11.2779</a>
  chicago: Molendijk, Arthur, Friedrich Bischoff, Chadalavada Rajendrakumar, Jiří
    Friml, Markus Braun, Simon Gilroy, and Klaus Palme. “Arabidopsis Thaliana Rop
    GTPases Are Localized to Tips of Root Hairs and Control Polar Growth.” <i>EMBO
    Journal</i>. Wiley-Blackwell, 2001. <a href="https://doi.org/10.1093/emboj/20.11.2779">https://doi.org/10.1093/emboj/20.11.2779</a>.
  ieee: A. Molendijk <i>et al.</i>, “Arabidopsis thaliana Rop GTPases are localized
    to tips of root hairs and control polar growth,” <i>EMBO Journal</i>, vol. 20,
    no. 11. Wiley-Blackwell, pp. 2779–2788, 2001.
  ista: Molendijk A, Bischoff F, Rajendrakumar C, Friml J, Braun M, Gilroy S, Palme
    K. 2001. Arabidopsis thaliana Rop GTPases are localized to tips of root hairs
    and control polar growth. EMBO Journal. 20(11), 2779–2788.
  mla: Molendijk, Arthur, et al. “Arabidopsis Thaliana Rop GTPases Are Localized to
    Tips of Root Hairs and Control Polar Growth.” <i>EMBO Journal</i>, vol. 20, no.
    11, Wiley-Blackwell, 2001, pp. 2779–88, doi:<a href="https://doi.org/10.1093/emboj/20.11.2779">10.1093/emboj/20.11.2779</a>.
  short: A. Molendijk, F. Bischoff, C. Rajendrakumar, J. Friml, M. Braun, S. Gilroy,
    K. Palme, EMBO Journal 20 (2001) 2779–2788.
date_created: 2018-12-11T12:00:40Z
date_published: 2001-06-01T00:00:00Z
date_updated: 2023-05-16T12:07:45Z
day: '01'
doi: 10.1093/emboj/20.11.2779
extern: '1'
external_id:
  pmid:
  - '11387211'
intvolume: '        20'
issue: '11'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC125484/
month: '06'
oa: 1
oa_version: Published Version
page: 2779 - 2788
pmid: 1
publication: EMBO Journal
publication_identifier:
  issn:
  - 0261-4189
publication_status: published
publisher: Wiley-Blackwell
publist_id: '3721'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Arabidopsis thaliana Rop GTPases are localized to tips of root hairs and control
  polar growth
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 20
year: '2001'
...
---
_id: '2982'
abstract:
- lang: eng
  text: Polar auxin transport is crucial for the regulation of auxin action and required
    for some light-regulated responses during plant development. We have found that
    two mutants of Arabidopsis - doc1, which displays altered expression of light-regulated
    genes, and tir3, known for its reduced auxin transport - have similar defects
    and define mutations in a single gene that we have renamed BIG. BIG is very similar
    to the Drosophila gene Calossin/Pushover, a member of a gene family also present
    in Caenorhabditis elegans and human genomes. The protein encoded by BIG is extraordinary
    in size, 560 kD, and contains several putative Zn-finger domains. Expression-profiling
    experiments indicate that altered expression of multiple light-regulated genes
    in doc1 mutants can be suppressed by elevated levels of auxin caused by overexpression
    of an auxin biosynthetic gene, suggesting that normal auxin distribution is required
    to maintain low-level expression of these genes in the dark. Double mutants of
    tir3 with the auxin mutants pin1, pid, and axr1 display severe defects in auxin-dependent
    growth of the inflorescence. Chemical inhibitors of auxin transport change the
    intracellular localization of the auxin efflux carrier PIN1 in doc1/tir3 mutants,
    supporting the idea that BIG is required for normal auxin efflux.
acknowledgement: "We thank Kim Hanson and Melissa McCarthy for technical support,
  and Adan Colon-Carmona, Jianming Li, and Karin Schumacher for their help in generating
  and identifying the doc1-3 T-DNA line. Seeds of ap3-1 and a cosmid library were
  supplied by the ABRC stock center. Jennifer Nemhauser made useful comments concerning
  this manuscript. This work was supported by grants from the Department of Energy
  (DE-FG03-89ER13993) and the National Science Foundation (MCB96-31390) to J.C., by
  grants from the Department of Energy (DE-FG02-98ER20313) and the National Institutes
  of Health (GM43644) to M.E., by a grant from DAAD to J.F., by a grant from DFG to
  K.P., and by a Marsden grant of New Zealand to J.P. and K.S. J.C. is an Associate
  Investigator of the Howard Hughes Medical Institute (HHMI), and Y.Z. is a HHMI fellow
  of the Life Sciences Research Foundation.\r\n\r\nThe publication costs of this article
  were defrayed in part by payment of page charges. This article must therefore be
  hereby marked “advertisement” in accordance with 18 USC section 1734 solely to indicate
  this fact."
article_processing_charge: No
article_type: original
author:
- first_name: Pedro
  full_name: Gil, Pedro
  last_name: Gil
- first_name: Elizabeth
  full_name: Dewey, Elizabeth
  last_name: Dewey
- first_name: Jirí
  full_name: Friml, Jirí
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
- first_name: Yunde
  full_name: Zhao, Yunde
  last_name: Zhao
- first_name: Kimberley
  full_name: Snowden, Kimberley
  last_name: Snowden
- first_name: Jo
  full_name: Putterill, Jo
  last_name: Putterill
- first_name: Klaus
  full_name: Palme, Klaus
  last_name: Palme
- first_name: Mark
  full_name: Estelle, Mark
  last_name: Estelle
- first_name: Joanne
  full_name: Chory, Joanne
  last_name: Chory
citation:
  ama: 'Gil P, Dewey E, Friml J, et al. BIG: A calossin-like protein required for
    polar auxin transport in Arabidopsis. <i>Genes and Development</i>. 2001;15(15):1985-1997.
    doi:<a href="https://doi.org/10.1101/gad.905201">10.1101/gad.905201</a>'
  apa: 'Gil, P., Dewey, E., Friml, J., Zhao, Y., Snowden, K., Putterill, J., … Chory,
    J. (2001). BIG: A calossin-like protein required for polar auxin transport in
    Arabidopsis. <i>Genes and Development</i>. Cold Spring Harbor Laboratory Press.
    <a href="https://doi.org/10.1101/gad.905201">https://doi.org/10.1101/gad.905201</a>'
  chicago: 'Gil, Pedro, Elizabeth Dewey, Jiří Friml, Yunde Zhao, Kimberley Snowden,
    Jo Putterill, Klaus Palme, Mark Estelle, and Joanne Chory. “BIG: A Calossin-like
    Protein Required for Polar Auxin Transport in Arabidopsis.” <i>Genes and Development</i>.
    Cold Spring Harbor Laboratory Press, 2001. <a href="https://doi.org/10.1101/gad.905201">https://doi.org/10.1101/gad.905201</a>.'
  ieee: 'P. Gil <i>et al.</i>, “BIG: A calossin-like protein required for polar auxin
    transport in Arabidopsis,” <i>Genes and Development</i>, vol. 15, no. 15. Cold
    Spring Harbor Laboratory Press, pp. 1985–1997, 2001.'
  ista: 'Gil P, Dewey E, Friml J, Zhao Y, Snowden K, Putterill J, Palme K, Estelle
    M, Chory J. 2001. BIG: A calossin-like protein required for polar auxin transport
    in Arabidopsis. Genes and Development. 15(15), 1985–1997.'
  mla: 'Gil, Pedro, et al. “BIG: A Calossin-like Protein Required for Polar Auxin
    Transport in Arabidopsis.” <i>Genes and Development</i>, vol. 15, no. 15, Cold
    Spring Harbor Laboratory Press, 2001, pp. 1985–97, doi:<a href="https://doi.org/10.1101/gad.905201">10.1101/gad.905201</a>.'
  short: P. Gil, E. Dewey, J. Friml, Y. Zhao, K. Snowden, J. Putterill, K. Palme,
    M. Estelle, J. Chory, Genes and Development 15 (2001) 1985–1997.
date_created: 2018-12-11T12:00:41Z
date_published: 2001-08-01T00:00:00Z
date_updated: 2023-05-16T11:59:47Z
day: '01'
doi: 10.1101/gad.905201
extern: '1'
external_id:
  pmid:
  - '11485992'
intvolume: '        15'
issue: '15'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC312751/
month: '08'
oa: 1
oa_version: Published Version
page: 1985 - 1997
pmid: 1
publication: Genes and Development
publication_identifier:
  issn:
  - 0890-9369
publication_status: published
publisher: Cold Spring Harbor Laboratory Press
publist_id: '3720'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'BIG: A calossin-like protein required for polar auxin transport in Arabidopsis'
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 15
year: '2001'
...
---
_id: '2983'
abstract:
- lang: eng
  text: Polar transport of the phytohormone auxin mediates various processes in plant
    growth and development, such as apical dominance, tropisms, vascular patterning
    and axis formation. This view is based largely on the effects of polar auxin transport
    inhibitors. These compounds disrupt auxin efflux from the cell but their mode
    of action is unknown. It is thought that polar auxin flux is caused by the asymmetric
    distribution of efflux carriers acting at the plasma membrane. The polar localization
    of efflux carrier candidate PIN1 supports this model. Here we show that the seemingly
    static localization of PIN1 results from rapid actin-dependent cycling between
    the plasma membrane and endosomal compartments. Auxin transport inhibitors block
    PIN1 cycling and inhibit trafficking of membrane proteins that are unrelated to
    auxin transport. Our data suggest that PIN1 cycling is of central importance for
    auxin transport and that auxin transport inhibitors affect efflux by generally
    interfering with membrane-trafficking processes. In support of our conclusion,
    the vesicle-trafficking inhibitor brefeldin A mimics physiological effects of
    auxin transport inhibitors.
article_processing_charge: No
article_type: letter_note
author:
- first_name: Niko
  full_name: Geldner, Niko
  last_name: Geldner
- first_name: Jirí
  full_name: Friml, Jirí
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
- first_name: York
  full_name: Stierhof, York
  last_name: Stierhof
- first_name: Gerd
  full_name: Jürgens, Gerd
  last_name: Jürgens
- first_name: Klaus
  full_name: Palme, Klaus
  last_name: Palme
citation:
  ama: Geldner N, Friml J, Stierhof Y, Jürgens G, Palme K. Auxin transport inhibitors
    block PIN1 cycling and vesicle trafficking. <i>Nature</i>. 2001;413(6854):425-428.
    doi:<a href="https://doi.org/10.1038/35096571">10.1038/35096571</a>
  apa: Geldner, N., Friml, J., Stierhof, Y., Jürgens, G., &#38; Palme, K. (2001).
    Auxin transport inhibitors block PIN1 cycling and vesicle trafficking. <i>Nature</i>.
    Nature Publishing Group. <a href="https://doi.org/10.1038/35096571">https://doi.org/10.1038/35096571</a>
  chicago: Geldner, Niko, Jiří Friml, York Stierhof, Gerd Jürgens, and Klaus Palme.
    “Auxin Transport Inhibitors Block PIN1 Cycling and Vesicle Trafficking.” <i>Nature</i>.
    Nature Publishing Group, 2001. <a href="https://doi.org/10.1038/35096571">https://doi.org/10.1038/35096571</a>.
  ieee: N. Geldner, J. Friml, Y. Stierhof, G. Jürgens, and K. Palme, “Auxin transport
    inhibitors block PIN1 cycling and vesicle trafficking,” <i>Nature</i>, vol. 413,
    no. 6854. Nature Publishing Group, pp. 425–428, 2001.
  ista: Geldner N, Friml J, Stierhof Y, Jürgens G, Palme K. 2001. Auxin transport
    inhibitors block PIN1 cycling and vesicle trafficking. Nature. 413(6854), 425–428.
  mla: Geldner, Niko, et al. “Auxin Transport Inhibitors Block PIN1 Cycling and Vesicle
    Trafficking.” <i>Nature</i>, vol. 413, no. 6854, Nature Publishing Group, 2001,
    pp. 425–28, doi:<a href="https://doi.org/10.1038/35096571">10.1038/35096571</a>.
  short: N. Geldner, J. Friml, Y. Stierhof, G. Jürgens, K. Palme, Nature 413 (2001)
    425–428.
date_created: 2018-12-11T12:00:41Z
date_published: 2001-09-27T00:00:00Z
date_updated: 2023-05-16T11:51:44Z
day: '27'
doi: 10.1038/35096571
extern: '1'
external_id:
  pmid:
  - '11574889'
intvolume: '       413'
issue: '6854'
language:
- iso: eng
month: '09'
oa_version: None
page: 425 - 428
pmid: 1
publication: Nature
publication_identifier:
  issn:
  - 0028-0836
publication_status: published
publisher: Nature Publishing Group
publist_id: '3719'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Auxin transport inhibitors block PIN1 cycling and vesicle trafficking
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 413
year: '2001'
...
---
_id: '2984'
abstract:
- lang: eng
  text: Auxins represent an important class of plant hormone that regulate plant development.
    Plants use specialized carrier proteins to transport the auxin indole-3-acetic
    acid (IAA) to target tissues. To date, efflux carrier-mediated polar auxin transport
    has been assumed to represent the sole mode of long distance IAA movement. Localization
    of the auxin permease AUX1 in the Arabidopsis root apex has revealed a novel phloem-based
    IAA transport pathway. AUX1, asymmetrically localized to the plasma membrane of
    root protophloem cells, is proposed to promote the acropetal, post-phloem movement
    of auxin to the root apex. MS analysis shows that IAA accumulation in aux1 mutant
    root apices is impaired, consistent with an AUX1 phloem unloading function. AUX1
    localization to columella and lateral root cap tissues of the Arabidopsis root
    apex reveals that the auxin permease regulates a second IAA transport pathway.
    Expression studies using an auxin-regulated reporter suggest that AUX1 is necessary
    for root gravitropism by facilitating basipetal auxin transport to distal elongation
    zone tissues.
acknowledgement: "We thank Ben Scheres and Marcus Grebe for critically reading the
  manuscript, Burkhard Schulz for providing advice about the HA epitope tag, and Denis
  Baker for valuable discussion. This work was funded by the BBSRC and European Commission
  grants to the LATIN and POPWOOD research consortia.\r\n\r\nThe publication costs
  of this article were defrayed in part by payment of page charges. This article must
  therefore be hereby marked “advertisement” in accordance with 18 USC section 1734
  solely to indicate this fact."
article_processing_charge: No
article_type: original
author:
- first_name: Ranjan
  full_name: Swarup, Ranjan
  last_name: Swarup
- first_name: Jirí
  full_name: Friml, Jirí
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
- first_name: Alan
  full_name: Marchant, Alan
  last_name: Marchant
- first_name: Karin
  full_name: Ljung, Karin
  last_name: Ljung
- first_name: Göran
  full_name: Sandberg, Göran
  last_name: Sandberg
- first_name: Klaus
  full_name: Palme, Klaus
  last_name: Palme
- first_name: Malcolm
  full_name: Bennett, Malcolm
  last_name: Bennett
citation:
  ama: Swarup R, Friml J, Marchant A, et al. Localization of the auxin permease AUX1
    suggests two functionally distinct hormone transport pathways operate in the Arabidopsis
    root apex. <i>Genes and Development</i>. 2001;15(20):2648-2653. doi:<a href="https://doi.org/10.1101/gad.210501">10.1101/gad.210501</a>
  apa: Swarup, R., Friml, J., Marchant, A., Ljung, K., Sandberg, G., Palme, K., &#38;
    Bennett, M. (2001). Localization of the auxin permease AUX1 suggests two functionally
    distinct hormone transport pathways operate in the Arabidopsis root apex. <i>Genes
    and Development</i>. Cold Spring Harbor Laboratory Press. <a href="https://doi.org/10.1101/gad.210501">https://doi.org/10.1101/gad.210501</a>
  chicago: Swarup, Ranjan, Jiří Friml, Alan Marchant, Karin Ljung, Göran Sandberg,
    Klaus Palme, and Malcolm Bennett. “Localization of the Auxin Permease AUX1 Suggests
    Two Functionally Distinct Hormone Transport Pathways Operate in the Arabidopsis
    Root Apex.” <i>Genes and Development</i>. Cold Spring Harbor Laboratory Press,
    2001. <a href="https://doi.org/10.1101/gad.210501">https://doi.org/10.1101/gad.210501</a>.
  ieee: R. Swarup <i>et al.</i>, “Localization of the auxin permease AUX1 suggests
    two functionally distinct hormone transport pathways operate in the Arabidopsis
    root apex,” <i>Genes and Development</i>, vol. 15, no. 20. Cold Spring Harbor
    Laboratory Press, pp. 2648–2653, 2001.
  ista: Swarup R, Friml J, Marchant A, Ljung K, Sandberg G, Palme K, Bennett M. 2001.
    Localization of the auxin permease AUX1 suggests two functionally distinct hormone
    transport pathways operate in the Arabidopsis root apex. Genes and Development.
    15(20), 2648–2653.
  mla: Swarup, Ranjan, et al. “Localization of the Auxin Permease AUX1 Suggests Two
    Functionally Distinct Hormone Transport Pathways Operate in the Arabidopsis Root
    Apex.” <i>Genes and Development</i>, vol. 15, no. 20, Cold Spring Harbor Laboratory
    Press, 2001, pp. 2648–53, doi:<a href="https://doi.org/10.1101/gad.210501">10.1101/gad.210501</a>.
  short: R. Swarup, J. Friml, A. Marchant, K. Ljung, G. Sandberg, K. Palme, M. Bennett,
    Genes and Development 15 (2001) 2648–2653.
date_created: 2018-12-11T12:00:41Z
date_published: 2001-10-15T00:00:00Z
date_updated: 2023-05-16T11:37:53Z
day: '15'
doi: 10.1101/gad.210501
extern: '1'
external_id:
  pmid:
  - '11641271'
intvolume: '        15'
issue: '20'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: ncbi.nlm.nih.gov/pmc/articles/PMC312818/
month: '10'
oa: 1
oa_version: Published Version
page: 2648 - 2653
pmid: 1
publication: Genes and Development
publication_identifier:
  issn:
  - Genes and Development
publication_status: published
publisher: Cold Spring Harbor Laboratory Press
publist_id: '3718'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Localization of the auxin permease AUX1 suggests two functionally distinct
  hormone transport pathways operate in the Arabidopsis root apex
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 15
year: '2001'
...
---
_id: '2985'
abstract:
- lang: eng
  text: The elimination voltammetry with linear scan (EVLS) was used to study adenine
    and cytosine reduction signals at the mercury electrode. In comparison with the
    linear scan voltammetry (which provides only one unresolved peak), two elimination
    functions provide good resolution of individual peaks and significant increase
    of sensitivity. The first elimination function eliminates the kinetic current
    (Ik) and conserves the diffusion current (Id). The second elimination function
    eliminates kinetic and charging currents (Ik and Ic) simultaneously and conserves
    the diffusion current (Id). Both functions give two well-resolved peaks of adenine
    and cytosine in a wide concentration range, while the linear sweep voltammetry
    gives badly resolved peaks due to hydrogen evolution. The best resolution of peaks
    is observed in acetate buffer at pH 3.8 and the detection limit for both substances
    is 500 nM. The concentration dependence of EVLS peak heights for one substance
    at the constant concentration of the other substance is linear. The peak potentials
    differ in these elimination functions. The difference in EVLS peak potentials
    gives the possibility to evaluate αna. Elimination voltammetry with linear scan
    contributes to the resolution of cathodic signals of purine and pyrimidine bases
    at very negative potentials near supporting electrolyte discharge. Copyright ©
    2001 Elsevier Science B.V.
article_processing_charge: No
article_type: original
author:
- first_name: Libuše
  full_name: Trnková, Libuše
  last_name: Trnková
- first_name: Jirí
  full_name: Friml, Jirí
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
- first_name: Oldřich
  full_name: Dračka, Oldřich
  last_name: Dračka
citation:
  ama: Trnková L, Friml J, Dračka O. Elimination voltammetry of adenine and cytosine
    mixtures. <i>Bioelectrochemistry</i>. 2001;54(2):131-136. doi:<a href="https://doi.org/10.1016/S1567-5394(01)00119-0">10.1016/S1567-5394(01)00119-0</a>
  apa: Trnková, L., Friml, J., &#38; Dračka, O. (2001). Elimination voltammetry of
    adenine and cytosine mixtures. <i>Bioelectrochemistry</i>. Elsevier. <a href="https://doi.org/10.1016/S1567-5394(01)00119-0">https://doi.org/10.1016/S1567-5394(01)00119-0</a>
  chicago: Trnková, Libuše, Jiří Friml, and Oldřich Dračka. “Elimination Voltammetry
    of Adenine and Cytosine Mixtures.” <i>Bioelectrochemistry</i>. Elsevier, 2001.
    <a href="https://doi.org/10.1016/S1567-5394(01)00119-0">https://doi.org/10.1016/S1567-5394(01)00119-0</a>.
  ieee: L. Trnková, J. Friml, and O. Dračka, “Elimination voltammetry of adenine and
    cytosine mixtures,” <i>Bioelectrochemistry</i>, vol. 54, no. 2. Elsevier, pp.
    131–136, 2001.
  ista: Trnková L, Friml J, Dračka O. 2001. Elimination voltammetry of adenine and
    cytosine mixtures. Bioelectrochemistry. 54(2), 131–136.
  mla: Trnková, Libuše, et al. “Elimination Voltammetry of Adenine and Cytosine Mixtures.”
    <i>Bioelectrochemistry</i>, vol. 54, no. 2, Elsevier, 2001, pp. 131–36, doi:<a
    href="https://doi.org/10.1016/S1567-5394(01)00119-0">10.1016/S1567-5394(01)00119-0</a>.
  short: L. Trnková, J. Friml, O. Dračka, Bioelectrochemistry 54 (2001) 131–136.
date_created: 2018-12-11T12:00:42Z
date_published: 2001-11-01T00:00:00Z
date_updated: 2023-05-15T14:48:44Z
day: '01'
doi: 10.1016/S1567-5394(01)00119-0
extern: '1'
external_id:
  pmid:
  - '11694393'
intvolume: '        54'
issue: '2'
language:
- iso: eng
month: '11'
oa_version: None
page: 131 - 136
pmid: 1
publication: Bioelectrochemistry
publication_identifier:
  isbn:
  - 1567-5394
publication_status: published
publisher: Elsevier
publist_id: '3717'
quality_controlled: '1'
status: public
title: Elimination voltammetry of adenine and cytosine mixtures
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 54
year: '2001'
...
---
_id: '3169'
abstract:
- lang: eng
  text: Several new algorithms for visual correspondence based on graph cuts [7, 14,
    17] have recently been developed. While these methods give very strong results
    in practice, they do not handle occlusions properly. Specifically, they treat
    the two input images asymmetrically, and they do not ensure that a pixel corresponds
    to at most one pixel in the other image. In this paper, we present a new method
    which properly addresses occlusions, while preserving the advantages of graph
    cut algorithms. We give experimental results for stereo as well as motion, which
    demonstrate that our method performs well both at detecting occlusions and computing
    disparities.
article_processing_charge: No
author:
- first_name: Vladimir
  full_name: Kolmogorov, Vladimir
  id: 3D50B0BA-F248-11E8-B48F-1D18A9856A87
  last_name: Kolmogorov
- first_name: Ramin
  full_name: Zabih, Ramin
  last_name: Zabih
citation:
  ama: 'Kolmogorov V, Zabih R. Computing visual correspondence with occlusions using
    graph cuts. In: <i>Proceedings of the 8th IEEE International Conference on Computer
    Vision</i>. Vol 2. IEEE; 2001:508-515. doi:<a href="https://doi.org/10.1109/ICCV.2001.937668">10.1109/ICCV.2001.937668</a>'
  apa: 'Kolmogorov, V., &#38; Zabih, R. (2001). Computing visual correspondence with
    occlusions using graph cuts. In <i>Proceedings of the 8th IEEE International Conference
    on Computer Vision</i> (Vol. 2, pp. 508–515). Vancouver, Canada: IEEE. <a href="https://doi.org/10.1109/ICCV.2001.937668">https://doi.org/10.1109/ICCV.2001.937668</a>'
  chicago: Kolmogorov, Vladimir, and Ramin Zabih. “Computing Visual Correspondence
    with Occlusions Using Graph Cuts.” In <i>Proceedings of the 8th IEEE International
    Conference on Computer Vision</i>, 2:508–15. IEEE, 2001. <a href="https://doi.org/10.1109/ICCV.2001.937668">https://doi.org/10.1109/ICCV.2001.937668</a>.
  ieee: V. Kolmogorov and R. Zabih, “Computing visual correspondence with occlusions
    using graph cuts,” in <i>Proceedings of the 8th IEEE International Conference
    on Computer Vision</i>, Vancouver, Canada, 2001, vol. 2, pp. 508–515.
  ista: 'Kolmogorov V, Zabih R. 2001. Computing visual correspondence with occlusions
    using graph cuts. Proceedings of the 8th IEEE International Conference on Computer
    Vision. ICCV: International Conference on Computer Vision vol. 2, 508–515.'
  mla: Kolmogorov, Vladimir, and Ramin Zabih. “Computing Visual Correspondence with
    Occlusions Using Graph Cuts.” <i>Proceedings of the 8th IEEE International Conference
    on Computer Vision</i>, vol. 2, IEEE, 2001, pp. 508–15, doi:<a href="https://doi.org/10.1109/ICCV.2001.937668">10.1109/ICCV.2001.937668</a>.
  short: V. Kolmogorov, R. Zabih, in:, Proceedings of the 8th IEEE International Conference
    on Computer Vision, IEEE, 2001, pp. 508–515.
conference:
  end_date: 2001-07-14
  location: Vancouver, Canada
  name: 'ICCV: International Conference on Computer Vision'
  start_date: 2001-07-07
date_created: 2018-12-11T12:01:47Z
date_published: 2001-08-01T00:00:00Z
date_updated: 2023-05-15T14:45:50Z
day: '01'
doi: 10.1109/ICCV.2001.937668
extern: '1'
intvolume: '         2'
language:
- iso: eng
month: '08'
oa_version: None
page: 508 - 515
publication: Proceedings of the 8th IEEE International Conference on Computer Vision
publication_identifier:
  isbn:
  - '0769511430'
publication_status: published
publisher: IEEE
publist_id: '3514'
quality_controlled: '1'
status: public
title: Computing visual correspondence with occlusions using graph cuts
type: conference
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 2
year: '2001'
...
---
_id: '3434'
abstract:
- lang: eng
  text: "This chapter contains sections titled:\r\n\r\nIntroduction\r\n\r\n- History\r\n\r\n-
    Developing an Intuition of Likelihood\r\n\r\n- Method of Maximum Likelihood\r\n\r\n-
    Bayesian Inference\r\n\r\n- Markov Chain Monte Carlo\r\n\r\n- Assessing Uncertainty
    of Phylogenies\r\n\r\n- Hypothesis Testing and Model Choice\r\n\r\n- Comparative
    Analysis\r\n\r\n- Conclusions\r\n\r\n- References"
article_processing_charge: No
author:
- first_name: John
  full_name: Huelsenbeck, John
  last_name: Huelsenbeck
- first_name: Jonathan P
  full_name: Bollback, Jonathan P
  id: 2C6FA9CC-F248-11E8-B48F-1D18A9856A87
  last_name: Bollback
  orcid: 0000-0002-4624-4612
citation:
  ama: 'Huelsenbeck J, Bollback JP. Application of the likelihood function in phylogenetic
    analysis. In: Balding D, Bishop M, Cannings C, eds. <i>Handbook of Statistical
    Genetics</i>. Wiley-Blackwell; 2001:415-439. doi:<a href="https://doi.org/10.1002/9780470061619.ch15">10.1002/9780470061619.ch15</a>'
  apa: Huelsenbeck, J., &#38; Bollback, J. P. (2001). Application of the likelihood
    function in phylogenetic analysis. In D. Balding, M. Bishop, &#38; C. Cannings
    (Eds.), <i>Handbook of Statistical Genetics</i> (pp. 415–439). Wiley-Blackwell.
    <a href="https://doi.org/10.1002/9780470061619.ch15">https://doi.org/10.1002/9780470061619.ch15</a>
  chicago: Huelsenbeck, John, and Jonathan P Bollback. “Application of the Likelihood
    Function in Phylogenetic Analysis.” In <i>Handbook of Statistical Genetics</i>,
    edited by David Balding, Martin Bishop, and Chriss Cannings, 415–39. Wiley-Blackwell,
    2001. <a href="https://doi.org/10.1002/9780470061619.ch15">https://doi.org/10.1002/9780470061619.ch15</a>.
  ieee: J. Huelsenbeck and J. P. Bollback, “Application of the likelihood function
    in phylogenetic analysis,” in <i>Handbook of Statistical Genetics</i>, D. Balding,
    M. Bishop, and C. Cannings, Eds. Wiley-Blackwell, 2001, pp. 415–439.
  ista: 'Huelsenbeck J, Bollback JP. 2001.Application of the likelihood function in
    phylogenetic analysis. In: Handbook of Statistical Genetics. , 415–439.'
  mla: Huelsenbeck, John, and Jonathan P. Bollback. “Application of the Likelihood
    Function in Phylogenetic Analysis.” <i>Handbook of Statistical Genetics</i>, edited
    by David Balding et al., Wiley-Blackwell, 2001, pp. 415–39, doi:<a href="https://doi.org/10.1002/9780470061619.ch15">10.1002/9780470061619.ch15</a>.
  short: J. Huelsenbeck, J.P. Bollback, in:, D. Balding, M. Bishop, C. Cannings (Eds.),
    Handbook of Statistical Genetics, Wiley-Blackwell, 2001, pp. 415–439.
date_created: 2018-12-11T12:03:19Z
date_published: 2001-01-01T00:00:00Z
date_updated: 2023-05-15T14:43:39Z
day: '01'
doi: 10.1002/9780470061619.ch15
editor:
- first_name: David
  full_name: Balding, David
  last_name: Balding
- first_name: Martin
  full_name: Bishop, Martin
  last_name: Bishop
- first_name: Chriss
  full_name: Cannings, Chriss
  last_name: Cannings
extern: '1'
language:
- iso: eng
month: '01'
oa_version: None
page: 415 - 439
publication: Handbook of Statistical Genetics
publication_identifier:
  isbn:
  - '9781119429142 '
publication_status: published
publisher: Wiley-Blackwell
publist_id: '2966'
quality_controlled: '1'
status: public
title: Application of the likelihood function in phylogenetic analysis
type: book_chapter
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
year: '2001'
...
---
_id: '3438'
abstract:
- lang: eng
  text: As a discipline, phylogenetics is becoming transformed by a flood of molecular
    data. These data allow broad questions to be asked about the history of life,
    but also present difficult statistical and computational problems. Bayesian inference
    of phylogeny brings a new perspective to a number of outstanding issues in evolutionary
    biology, including the analysis of large phylogenetic trees and complex evolutionary
    models and the detection of the footprint of natural selection in DNA sequences.
article_processing_charge: No
author:
- first_name: John
  full_name: Huelsenbeck, John
  last_name: Huelsenbeck
- first_name: Fredrik
  full_name: Ronquist, Fredrik
  last_name: Ronquist
- first_name: Rasmus
  full_name: Nielsen, Rasmus
  last_name: Nielsen
- first_name: Jonathan P
  full_name: Bollback, Jonathan P
  id: 2C6FA9CC-F248-11E8-B48F-1D18A9856A87
  last_name: Bollback
  orcid: 0000-0002-4624-4612
citation:
  ama: Huelsenbeck J, Ronquist F, Nielsen R, Bollback JP. Bayesian inference of phylogeny
    and its impact on evolutionary biology. <i>Science</i>. 2001;294(5550):2310-2314.
    doi:<a href="https://doi.org/10.1126/science.1065889">10.1126/science.1065889</a>
  apa: Huelsenbeck, J., Ronquist, F., Nielsen, R., &#38; Bollback, J. P. (2001). Bayesian
    inference of phylogeny and its impact on evolutionary biology. <i>Science</i>.
    American Association for the Advancement of Science. <a href="https://doi.org/10.1126/science.1065889">https://doi.org/10.1126/science.1065889</a>
  chicago: Huelsenbeck, John, Fredrik Ronquist, Rasmus Nielsen, and Jonathan P Bollback.
    “Bayesian Inference of Phylogeny and Its Impact on Evolutionary Biology.” <i>Science</i>.
    American Association for the Advancement of Science, 2001. <a href="https://doi.org/10.1126/science.1065889">https://doi.org/10.1126/science.1065889</a>.
  ieee: J. Huelsenbeck, F. Ronquist, R. Nielsen, and J. P. Bollback, “Bayesian inference
    of phylogeny and its impact on evolutionary biology,” <i>Science</i>, vol. 294,
    no. 5550. American Association for the Advancement of Science, pp. 2310–2314,
    2001.
  ista: Huelsenbeck J, Ronquist F, Nielsen R, Bollback JP. 2001. Bayesian inference
    of phylogeny and its impact on evolutionary biology. Science. 294(5550), 2310–2314.
  mla: Huelsenbeck, John, et al. “Bayesian Inference of Phylogeny and Its Impact on
    Evolutionary Biology.” <i>Science</i>, vol. 294, no. 5550, American Association
    for the Advancement of Science, 2001, pp. 2310–14, doi:<a href="https://doi.org/10.1126/science.1065889">10.1126/science.1065889</a>.
  short: J. Huelsenbeck, F. Ronquist, R. Nielsen, J.P. Bollback, Science 294 (2001)
    2310–2314.
date_created: 2018-12-11T12:03:20Z
date_published: 2001-12-14T00:00:00Z
date_updated: 2023-05-15T14:10:13Z
day: '14'
doi: 10.1126/science.1065889
extern: '1'
external_id:
  pmid:
  - '11743192 '
intvolume: '       294'
issue: '5550'
language:
- iso: eng
month: '12'
oa_version: None
page: 2310 - 2314
pmid: 1
publication: Science
publication_identifier:
  issn:
  - 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science
publist_id: '2962'
quality_controlled: '1'
status: public
title: Bayesian inference of phylogeny and its impact on evolutionary biology
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 294
year: '2001'
...
---
_id: '3439'
abstract:
- lang: eng
  text: High molecular weight DNA was extracted from the primary Neotropical malaria
    vector, Anopheles darlingi from Capanema, Pará, Brazil, to create a small insert
    genomic library, and then a phagemid library. Enriched sublibraries were constructed
    from the phagemid library using a microsatellite oligo primed second strand synthesis
    protocol. The resulting 242 760 individual clones were screened. The mean clone
    size of the positive clones was 302 bp. Flanking primers were designed for each
    suitable microsatellite sequence. Eight polymorphic loci were optimized and characterized.
    The allele size ranges are based on 253 samples of A. darlingi from eastern Amazonian
    and central Brazil.
acknowledgement: For  support  in  Brazil  we  thank  D.  Galiza,  R.N.L.  Lacerda,E.P.
  Santa Rosa, M.N.O. Segura, and R.T.L. de Souza. We also thankM.J.  Braun  for  allowing  work  on  the  library  construction  at  theLaboratory
  of Molecular Systematics, Washington. Supported byNIH AI 40116 to JEC and Instituto
  Evandro Chagas, Belém, Brazil.
article_processing_charge: No
article_type: original
author:
- first_name: Jan
  full_name: Conn, Jan
  last_name: Conn
- first_name: Jonathan P
  full_name: Bollback, Jonathan P
  id: 2C6FA9CC-F248-11E8-B48F-1D18A9856A87
  last_name: Bollback
  orcid: 0000-0002-4624-4612
- first_name: David
  full_name: Onyabe, David
  last_name: Onyabe
- first_name: Tessa
  full_name: Robinson, Tessa
  last_name: Robinson
- first_name: Richard
  full_name: Wilkerson, Richard
  last_name: Wilkerson
- first_name: Marinete
  full_name: Povoa, Marinete
  last_name: Povoa
citation:
  ama: Conn J, Bollback JP, Onyabe D, Robinson T, Wilkerson R, Povoa M. Isolation
    of polymorphic microsatellite markers from the malaria vector Anopheles darlingi.
    <i>Molecular Ecology Notes</i>. 2001;1(4):223-225. doi:<a href="https://doi.org/
    10.1046/j.1471-8278.2001.00078.x"> 10.1046/j.1471-8278.2001.00078.x</a>
  apa: Conn, J., Bollback, J. P., Onyabe, D., Robinson, T., Wilkerson, R., &#38; Povoa,
    M. (2001). Isolation of polymorphic microsatellite markers from the malaria vector
    Anopheles darlingi. <i>Molecular Ecology Notes</i>. Wiley-Blackwell. <a href="https://doi.org/
    10.1046/j.1471-8278.2001.00078.x">https://doi.org/ 10.1046/j.1471-8278.2001.00078.x</a>
  chicago: Conn, Jan, Jonathan P Bollback, David Onyabe, Tessa Robinson, Richard Wilkerson,
    and Marinete Povoa. “Isolation of Polymorphic Microsatellite Markers from the
    Malaria Vector Anopheles Darlingi.” <i>Molecular Ecology Notes</i>. Wiley-Blackwell,
    2001. <a href="https://doi.org/ 10.1046/j.1471-8278.2001.00078.x">https://doi.org/
    10.1046/j.1471-8278.2001.00078.x</a>.
  ieee: J. Conn, J. P. Bollback, D. Onyabe, T. Robinson, R. Wilkerson, and M. Povoa,
    “Isolation of polymorphic microsatellite markers from the malaria vector Anopheles
    darlingi,” <i>Molecular Ecology Notes</i>, vol. 1, no. 4. Wiley-Blackwell, pp.
    223–225, 2001.
  ista: Conn J, Bollback JP, Onyabe D, Robinson T, Wilkerson R, Povoa M. 2001. Isolation
    of polymorphic microsatellite markers from the malaria vector Anopheles darlingi.
    Molecular Ecology Notes. 1(4), 223–225.
  mla: Conn, Jan, et al. “Isolation of Polymorphic Microsatellite Markers from the
    Malaria Vector Anopheles Darlingi.” <i>Molecular Ecology Notes</i>, vol. 1, no.
    4, Wiley-Blackwell, 2001, pp. 223–25, doi:<a href="https://doi.org/ 10.1046/j.1471-8278.2001.00078.x">
    10.1046/j.1471-8278.2001.00078.x</a>.
  short: J. Conn, J.P. Bollback, D. Onyabe, T. Robinson, R. Wilkerson, M. Povoa, Molecular
    Ecology Notes 1 (2001) 223–225.
date_created: 2018-12-11T12:03:20Z
date_published: 2001-12-01T00:00:00Z
date_updated: 2023-05-15T13:58:49Z
day: '01'
doi: ' 10.1046/j.1471-8278.2001.00078.x'
extern: '1'
intvolume: '         1'
issue: '4'
language:
- iso: eng
month: '12'
oa_version: None
page: 223 - 225
publication: Molecular Ecology Notes
publication_identifier:
  issn:
  - 1471-8278
publication_status: published
publisher: Wiley-Blackwell
publist_id: '2961'
quality_controlled: '1'
status: public
title: Isolation of polymorphic microsatellite markers from the malaria vector Anopheles
  darlingi
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 1
year: '2001'
...
---
_id: '3440'
abstract:
- lang: eng
  text: "Several methods have been proposed to infer the states at the ancestral nodes
    on a phylogeny. These methods assume a specific tree and set of branch lengths
    when estimating the ancestral character state. Inferences of the ancestral states,
    then, are conditioned on the tree and branch lengths being true. We develop a
    hierarchical Bayes method for inferring the ancestral states on a tree. The method
    integrates over uncertainty in the tree, branch lengths, and substitution model
    parameters by using Markov chain Monte Carlo. We compare the hierarchical Bayes
    inferences of ancestral states with inferences of ancestral states made under
    the assumption that a specific tree is correct. We find that the methods are correlated,
    but that accommodating uncertainty in parameters of the phylogenetic model can
    make inferences of ancestral states even more uncertain than they would be in
    an empirical Bayes analysis.\r\n"
article_processing_charge: No
article_type: original
author:
- first_name: John
  full_name: Huelsenbeck, John
  last_name: Huelsenbeck
- first_name: Jonathan P
  full_name: Bollback, Jonathan P
  id: 2C6FA9CC-F248-11E8-B48F-1D18A9856A87
  last_name: Bollback
  orcid: 0000-0002-4624-4612
citation:
  ama: Huelsenbeck J, Bollback JP. Empirical and hierarchical Bayesian estimation
    of ancestral states. <i>Systematic Biology</i>. 2001;50(3):351-366. doi:<a href="https://doi.org/10.1080/10635150119871">10.1080/10635150119871</a>
  apa: Huelsenbeck, J., &#38; Bollback, J. P. (2001). Empirical and hierarchical Bayesian
    estimation of ancestral states. <i>Systematic Biology</i>. Oxford University Press.
    <a href="https://doi.org/10.1080/10635150119871">https://doi.org/10.1080/10635150119871</a>
  chicago: Huelsenbeck, John, and Jonathan P Bollback. “Empirical and Hierarchical
    Bayesian Estimation of Ancestral States.” <i>Systematic Biology</i>. Oxford University
    Press, 2001. <a href="https://doi.org/10.1080/10635150119871">https://doi.org/10.1080/10635150119871</a>.
  ieee: J. Huelsenbeck and J. P. Bollback, “Empirical and hierarchical Bayesian estimation
    of ancestral states,” <i>Systematic Biology</i>, vol. 50, no. 3. Oxford University
    Press, pp. 351–366, 2001.
  ista: Huelsenbeck J, Bollback JP. 2001. Empirical and hierarchical Bayesian estimation
    of ancestral states. Systematic Biology. 50(3), 351–366.
  mla: Huelsenbeck, John, and Jonathan P. Bollback. “Empirical and Hierarchical Bayesian
    Estimation of Ancestral States.” <i>Systematic Biology</i>, vol. 50, no. 3, Oxford
    University Press, 2001, pp. 351–66, doi:<a href="https://doi.org/10.1080/10635150119871">10.1080/10635150119871</a>.
  short: J. Huelsenbeck, J.P. Bollback, Systematic Biology 50 (2001) 351–366.
date_created: 2018-12-11T12:03:20Z
date_published: 2001-05-01T00:00:00Z
date_updated: 2023-05-15T13:54:01Z
day: '01'
doi: 10.1080/10635150119871
extern: '1'
external_id:
  pmid:
  - '12116580'
intvolume: '        50'
issue: '3'
language:
- iso: eng
month: '05'
oa_version: None
page: 351 - 366
pmid: 1
publication: Systematic Biology
publication_identifier:
  issn:
  - 0039-7989
publication_status: published
publisher: Oxford University Press
publist_id: '2960'
quality_controlled: '1'
status: public
title: Empirical and hierarchical Bayesian estimation of ancestral states
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 50
year: '2001'
...
---
_id: '3447'
author:
- first_name: Krishnendu
  full_name: Krishnendu Chatterjee
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Pallab
  full_name: Dasgupta, Pallab
  last_name: Dasgupta
- first_name: Partha
  full_name: Chakrabarti, Partha P
  last_name: Chakrabarti
citation:
  ama: 'Chatterjee K, Dasgupta P, Chakrabarti P. Weighted quantified computation tree
    logic. In: Elsevier; 2001.'
  apa: 'Chatterjee, K., Dasgupta, P., &#38; Chakrabarti, P. (2001). Weighted quantified
    computation tree logic. Presented at the CIT: Conference on Information Technology,
    Elsevier.'
  chicago: Chatterjee, Krishnendu, Pallab Dasgupta, and Partha Chakrabarti. “Weighted
    Quantified Computation Tree Logic.” Elsevier, 2001.
  ieee: 'K. Chatterjee, P. Dasgupta, and P. Chakrabarti, “Weighted quantified computation
    tree logic,” presented at the CIT: Conference on Information Technology, 2001.'
  ista: 'Chatterjee K, Dasgupta P, Chakrabarti P. 2001. Weighted quantified computation
    tree logic. CIT: Conference on Information Technology.'
  mla: Chatterjee, Krishnendu, et al. <i>Weighted Quantified Computation Tree Logic</i>.
    Elsevier, 2001.
  short: K. Chatterjee, P. Dasgupta, P. Chakrabarti, in:, Elsevier, 2001.
conference:
  name: 'CIT: Conference on Information Technology'
date_created: 2018-12-11T12:03:23Z
date_published: 2001-11-14T00:00:00Z
date_updated: 2021-01-12T07:43:31Z
day: '14'
extern: 1
month: '11'
publication_status: published
publisher: Elsevier
publist_id: '2940'
quality_controlled: 0
status: public
title: Weighted quantified computation tree logic
type: conference
year: '2001'
...
---
_id: '3493'
abstract:
- lang: eng
  text: Although agonists and competitive antagonists presumably occupy overlapping
    binding sites on ligand-gated channels, these interactions cannot be identical
    because agonists cause channel opening whereas antagonists do not. One explanation
    is that only agonist binding performs enough work on the receptor to cause the
    conformational changes that lead to gating. This idea is supported by agonist
    binding rates at GABAA and nicotinic acetylcholine receptors that are slower than
    expected for a diffusion-limited process, suggesting that agonist binding involves
    an energy-requiring event. This hypothesis predicts that competitive antagonist
    binding should require less activation energy than agonist binding. To test this
    idea, we developed a novel deconvolution-based method to compare binding and unbinding
    kinetics of GABAA receptor agonists and antagonists in outside-out patches from
    rat hippocampal neurons. Agonist and antagonist unbinding rates were steeply correlated
    with affinity. Unlike the agonists, three of the four antagonists tested had binding
    rates that were fast, independent of affinity, and could be accounted for by diffusion-
    and dehydration-limited processes. In contrast, agonist binding involved additional
    energy-requiring steps, consistent with the idea that channel gating is initiated
    by agonist-triggered movements within the ligand binding site. Antagonist binding
    does not appear to produce such movements, and may in fact prevent them.
article_processing_charge: No
article_type: original
author:
- first_name: M.V
  full_name: Jones, M.V
  last_name: Jones
- first_name: Peter M
  full_name: Jonas, Peter M
  id: 353C1B58-F248-11E8-B48F-1D18A9856A87
  last_name: Jonas
  orcid: 0000-0001-5001-4804
- first_name: Y.
  full_name: Sahara, Y.
  last_name: Sahara
- first_name: G.
  full_name: Westbrook, G.
  last_name: Westbrook
citation:
  ama: Jones M., Jonas PM, Sahara Y, Westbrook G. Microscopic kinetics and energetics
    distinguish GABAA receptor agonists from antagonists. <i>Biophysical Journal</i>.
    2001;81(5):2660-2670. doi:<a href="https://doi.org/10.1016/S0006-3495(01)75909-7
    ">10.1016/S0006-3495(01)75909-7 </a>
  apa: Jones, M. ., Jonas, P. M., Sahara, Y., &#38; Westbrook, G. (2001). Microscopic
    kinetics and energetics distinguish GABAA receptor agonists from antagonists.
    <i>Biophysical Journal</i>. Biophysical Society. <a href="https://doi.org/10.1016/S0006-3495(01)75909-7
    ">https://doi.org/10.1016/S0006-3495(01)75909-7 </a>
  chicago: Jones, M.V, Peter M Jonas, Y. Sahara, and G. Westbrook. “Microscopic Kinetics
    and Energetics Distinguish GABAA Receptor Agonists from Antagonists.” <i>Biophysical
    Journal</i>. Biophysical Society, 2001. <a href="https://doi.org/10.1016/S0006-3495(01)75909-7
    ">https://doi.org/10.1016/S0006-3495(01)75909-7 </a>.
  ieee: M. . Jones, P. M. Jonas, Y. Sahara, and G. Westbrook, “Microscopic kinetics
    and energetics distinguish GABAA receptor agonists from antagonists,” <i>Biophysical
    Journal</i>, vol. 81, no. 5. Biophysical Society, pp. 2660–2670, 2001.
  ista: Jones M., Jonas PM, Sahara Y, Westbrook G. 2001. Microscopic kinetics and
    energetics distinguish GABAA receptor agonists from antagonists. Biophysical Journal.
    81(5), 2660–2670.
  mla: Jones, M. .., et al. “Microscopic Kinetics and Energetics Distinguish GABAA
    Receptor Agonists from Antagonists.” <i>Biophysical Journal</i>, vol. 81, no.
    5, Biophysical Society, 2001, pp. 2660–70, doi:<a href="https://doi.org/10.1016/S0006-3495(01)75909-7
    ">10.1016/S0006-3495(01)75909-7 </a>.
  short: M.. Jones, P.M. Jonas, Y. Sahara, G. Westbrook, Biophysical Journal 81 (2001)
    2660–2670.
date_created: 2018-12-11T12:03:37Z
date_published: 2001-11-01T00:00:00Z
date_updated: 2023-05-15T13:50:21Z
day: '01'
doi: '10.1016/S0006-3495(01)75909-7 '
extern: '1'
external_id:
  pmid:
  - '11606279'
intvolume: '        81'
issue: '5'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1301733/
month: '11'
oa: 1
oa_version: Published Version
page: 2660 - 2670
pmid: 1
publication: Biophysical Journal
publication_identifier:
  issn:
  - 0006-3495
publication_status: published
publisher: Biophysical Society
publist_id: '2894'
quality_controlled: '1'
status: public
title: Microscopic kinetics and energetics distinguish GABAA receptor agonists from
  antagonists
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 81
year: '2001'
...
---
_id: '3494'
abstract:
- lang: eng
  text: 'Mutual synaptic interactions between GABAergic interneurons are thought to
    be of critical importance for the generation of network oscillations and for temporal
    encoding of information in the hippocampus. However, the functional properties
    of synaptic transmission between hippocampal interneurons are largely unknown.
    We have made paired recordings from basket cells (BCs) in the dentate gyrus of
    rat hippocampal slices, followed by correlated light and electron microscopical
    analysis. Unitary GABAAreceptor-mediated IPSCs at BC–BC synapses recorded at the
    soma showed a fast rise and decay, with a mean decay time constant of 2.5 ± 0.2
    msec (32°C). Synaptic transmission at BC–BC synapses showed paired-pulse depression
    (PPD) (32 ± 5% for 10 msec interpulse intervals) and multiple-pulse depression
    during repetitive stimulation. Detailed passive cable model simulations based
    on somatodendritic morphology and localization of synaptic contacts further indicated
    that the conductance change at the postsynaptic site was even faster, decaying
    with a mean time constant of 1.8 ± 0.6 msec. Sequential triple recordings revealed
    that the decay time course of IPSCs at BC–BC synapses was approximately twofold
    faster than that at BC–granule cell synapses, whereas the extent of PPD was comparable.
    To examine the consequences of the fast postsynaptic conductance change for the
    generation of oscillatory activity, we developed a computational model of an interneuron
    network. The model showed robust oscillations at frequencies &gt;60 Hz if the
    excitatory drive was sufficiently large. Thus the fast conductance change at interneuron–interneuron
    synapses may promote the generation of high-frequency oscillations observed in
    the dentate gyrusin vivo. '
acknowledgement: This work was supported by grants of the Deutsche Forschungsgemeinschaft
  (SFB 505/C6) and the Human Frontiers Science Program Organization (RG0017/1998-B).
  We thank Drs. M. V. Jones, J. Bischofberger, and U. Kraushaar for critically reading
  this manuscript. We also thank B. Taskin and A. Roth for advice in the use of reconstruction
  and modeling software, and S. Nestel, M. Winter, and A. Blomenkamp for technical
  assistance.
article_processing_charge: No
article_type: original
author:
- first_name: Marlene
  full_name: Bartos, Marlene
  last_name: Bartos
- first_name: Imre
  full_name: Vida, Imre
  last_name: Vida
- first_name: Michael
  full_name: Frotscher, Michael
  last_name: Frotscher
- first_name: Jörg
  full_name: Geiger, Jörg
  last_name: Geiger
- first_name: Peter M
  full_name: Jonas, Peter M
  id: 353C1B58-F248-11E8-B48F-1D18A9856A87
  last_name: Jonas
  orcid: 0000-0001-5001-4804
citation:
  ama: Bartos M, Vida I, Frotscher M, Geiger J, Jonas PM. Rapid signaling at inhibitory
    synapses in a dentate gyrus interneuron network. <i>Journal of Neuroscience</i>.
    2001;21(8):2687-2698. doi:<a href="https://doi.org/10.1523/JNEUROSCI.21-08-02687.2001">10.1523/JNEUROSCI.21-08-02687.2001</a>
  apa: Bartos, M., Vida, I., Frotscher, M., Geiger, J., &#38; Jonas, P. M. (2001).
    Rapid signaling at inhibitory synapses in a dentate gyrus interneuron network.
    <i>Journal of Neuroscience</i>. Society for Neuroscience. <a href="https://doi.org/10.1523/JNEUROSCI.21-08-02687.2001">https://doi.org/10.1523/JNEUROSCI.21-08-02687.2001</a>
  chicago: Bartos, Marlene, Imre Vida, Michael Frotscher, Jörg Geiger, and Peter M
    Jonas. “Rapid Signaling at Inhibitory Synapses in a Dentate Gyrus Interneuron
    Network.” <i>Journal of Neuroscience</i>. Society for Neuroscience, 2001. <a href="https://doi.org/10.1523/JNEUROSCI.21-08-02687.2001">https://doi.org/10.1523/JNEUROSCI.21-08-02687.2001</a>.
  ieee: M. Bartos, I. Vida, M. Frotscher, J. Geiger, and P. M. Jonas, “Rapid signaling
    at inhibitory synapses in a dentate gyrus interneuron network.,” <i>Journal of
    Neuroscience</i>, vol. 21, no. 8. Society for Neuroscience, pp. 2687–2698, 2001.
  ista: Bartos M, Vida I, Frotscher M, Geiger J, Jonas PM. 2001. Rapid signaling at
    inhibitory synapses in a dentate gyrus interneuron network. Journal of Neuroscience.
    21(8), 2687–2698.
  mla: Bartos, Marlene, et al. “Rapid Signaling at Inhibitory Synapses in a Dentate
    Gyrus Interneuron Network.” <i>Journal of Neuroscience</i>, vol. 21, no. 8, Society
    for Neuroscience, 2001, pp. 2687–98, doi:<a href="https://doi.org/10.1523/JNEUROSCI.21-08-02687.2001">10.1523/JNEUROSCI.21-08-02687.2001</a>.
  short: M. Bartos, I. Vida, M. Frotscher, J. Geiger, P.M. Jonas, Journal of Neuroscience
    21 (2001) 2687–2698.
date_created: 2018-12-11T12:03:37Z
date_published: 2001-04-15T00:00:00Z
date_updated: 2023-05-15T13:47:04Z
day: '15'
doi: 10.1523/JNEUROSCI.21-08-02687.2001
extern: '1'
external_id:
  pmid:
  - '11306622'
intvolume: '        21'
issue: '8'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: ncbi.nlm.nih.gov/pmc/articles/PMC6762544/
month: '04'
oa: 1
oa_version: Published Version
page: 2687 - 2698
pmid: 1
publication: Journal of Neuroscience
publication_identifier:
  issn:
  - 0270-6474
publication_status: published
publisher: Society for Neuroscience
publist_id: '2893'
quality_controlled: '1'
status: public
title: Rapid signaling at inhibitory synapses in a dentate gyrus interneuron network.
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 21
year: '2001'
...
---
_id: '3495'
abstract:
- lang: eng
  text: High Ca2+ permeability and its control by voltage-dependent Mg2+ block are
    defining features of NMDA receptors. These features are lost if the principal
    NR1 subunit carries an asparagine (N) to arginine (R) substitution in a critical
    channel site at NR1 position 598. NR1(R) expression from a single allele in gene-targeted
    NR1+/R mice is lethal soon after birth, precluding analysis of altered synaptic
    functions later in life. We therefore employed the forebrain specific αCaMKII
    promoter to drive tTA-mediated tetracyclin sensitive transcription of transgenes
    for NR1(R) and for lacZ as reporter. Transgene expression was observed in cortex,
    striatum, hippocampus, amygdala and olfactory bulb and was mosaic in all these
    forebrain regions. It was highest in olfactory bulb granule cells, in most of
    which Ca2+ permeability and voltage-dependent Mg2+ block of NMDA receptors were
    reduced to different extents. This indicates significant impairment of NMDA receptor
    function by NR1(R) in presence of the wild-type NR1 complement. Indeed, even though
    NR1(R) mRNA constituted only 18% of the entire NR1 mRNA population in forebrain,
    the transgenic mice died during adolescence unless transgene expression was suppressed
    by doxycycline. Thus, glutamate receptor function can be altered in the mouse
    by regulated NR1(R) transgene expression.
acknowledgement: 'This work was supported in part by grants from the 358 (1992) 36–41.Deutsche
  Forschungsgemeinschaft (Bi 642 / 1-2) and the Volkswagen foundation. '
article_processing_charge: No
article_type: original
author:
- first_name: Jasna
  full_name: Jerecic, Jasna
  last_name: Jerecic
- first_name: Christian
  full_name: Schulze, Christian
  last_name: Schulze
- first_name: Peter M
  full_name: Jonas, Peter M
  id: 353C1B58-F248-11E8-B48F-1D18A9856A87
  last_name: Jonas
  orcid: 0000-0001-5001-4804
- first_name: Rolf
  full_name: Sprengel, Rolf
  last_name: Sprengel
- first_name: Peter
  full_name: Seeburg, Peter
  last_name: Seeburg
- first_name: Joseph
  full_name: Bischofberger, Joseph
  last_name: Bischofberger
citation:
  ama: Jerecic J, Schulze C, Jonas PM, Sprengel R, Seeburg P, Bischofberger J. Impaired
    NMDA receptor function in mouse olfactory bulb neurons by tetracycline-sensitive
    NR1 (N598R) expression. <i>Molecular Brain Research</i>. 2001;94(1-2):96-104.
    doi:<a href="https://doi.org/10.1016/S0169-328X(01)00221-2">10.1016/S0169-328X(01)00221-2</a>
  apa: Jerecic, J., Schulze, C., Jonas, P. M., Sprengel, R., Seeburg, P., &#38; Bischofberger,
    J. (2001). Impaired NMDA receptor function in mouse olfactory bulb neurons by
    tetracycline-sensitive NR1 (N598R) expression. <i>Molecular Brain Research</i>.
    Elsevier. <a href="https://doi.org/10.1016/S0169-328X(01)00221-2">https://doi.org/10.1016/S0169-328X(01)00221-2</a>
  chicago: Jerecic, Jasna, Christian Schulze, Peter M Jonas, Rolf Sprengel, Peter
    Seeburg, and Joseph Bischofberger. “Impaired NMDA Receptor Function in Mouse Olfactory
    Bulb Neurons by Tetracycline-Sensitive NR1 (N598R) Expression.” <i>Molecular Brain
    Research</i>. Elsevier, 2001. <a href="https://doi.org/10.1016/S0169-328X(01)00221-2">https://doi.org/10.1016/S0169-328X(01)00221-2</a>.
  ieee: J. Jerecic, C. Schulze, P. M. Jonas, R. Sprengel, P. Seeburg, and J. Bischofberger,
    “Impaired NMDA receptor function in mouse olfactory bulb neurons by tetracycline-sensitive
    NR1 (N598R) expression,” <i>Molecular Brain Research</i>, vol. 94, no. 1–2. Elsevier,
    pp. 96–104, 2001.
  ista: Jerecic J, Schulze C, Jonas PM, Sprengel R, Seeburg P, Bischofberger J. 2001.
    Impaired NMDA receptor function in mouse olfactory bulb neurons by tetracycline-sensitive
    NR1 (N598R) expression. Molecular Brain Research. 94(1–2), 96–104.
  mla: Jerecic, Jasna, et al. “Impaired NMDA Receptor Function in Mouse Olfactory
    Bulb Neurons by Tetracycline-Sensitive NR1 (N598R) Expression.” <i>Molecular Brain
    Research</i>, vol. 94, no. 1–2, Elsevier, 2001, pp. 96–104, doi:<a href="https://doi.org/10.1016/S0169-328X(01)00221-2">10.1016/S0169-328X(01)00221-2</a>.
  short: J. Jerecic, C. Schulze, P.M. Jonas, R. Sprengel, P. Seeburg, J. Bischofberger,
    Molecular Brain Research 94 (2001) 96–104.
date_created: 2018-12-11T12:03:38Z
date_published: 2001-10-19T00:00:00Z
date_updated: 2023-05-15T13:42:32Z
day: '19'
doi: 10.1016/S0169-328X(01)00221-2
extern: '1'
external_id:
  pmid:
  - '11597769'
intvolume: '        94'
issue: 1-2
language:
- iso: eng
month: '10'
oa_version: None
page: 96 - 104
pmid: 1
publication: Molecular Brain Research
publication_identifier:
  issn:
  - 0169-328X
publication_status: published
publisher: Elsevier
publist_id: '2892'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Impaired NMDA receptor function in mouse olfactory bulb neurons by tetracycline-sensitive
  NR1 (N598R) expression
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 94
year: '2001'
...
---
_id: '3496'
abstract:
- lang: eng
  text: 'The mossy fiber-CA3 pyramidal neuron synapse is a main component of the hippocampal
    trisynaptic circuitry. Recent studies, however, suggested that inhibitory interneurons
    are the major targets of the mossy fiber system. To study the regulation of mossy
    fiber-interneuron excitation, we examined unitary and compound excitatory postsynaptic
    currents in dentate gyrus basket cells, evoked by paired recording between granule
    and basket cells or extracellular stimulation of mossy fiber collaterals. The
    application of an associative high-frequency stimulation paradigm induced posttetanic
    potentiation (PTP) followed by homosynaptic long-term potentiation (LTP). Analysis
    of numbers of failures, coefficient of variation, and paired-pulse modulation
    indicated that both PTP and LTP were expressed presynaptically. The Ca2+ chelator
    1,2-bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid (BAPTA) did not affect
    PTP or LTP at a concentration of 10 mM but attenuated LTP at a concentration of
    30 mM. Both forskolin, an adenylyl cyclase activator, and phorbolester diacetate,
    a protein kinase C stimulator, lead to a long-lasting increase in excitatory postsynaptic
    current amplitude. H-89, a protein kinase A inhibitor, and bisindolylmaleimide,
    a protein kinase C antagonist, reduced PTP, whereas only bisindolylmaleimide reduced
    LTP. These results may suggest a differential contribution of protein kinase A
    and C pathways to mossy fiber-interneuron plasticity. Interneuron PTP and LTP
    may provide mechanisms to maintain the balance between synaptic excitation of
    interneurons and that of principal neurons in the dentate gyrus-CA3 network. '
acknowledgement: We thank Drs. J. Bischofberger and M. Martina for critically reading
  an earlier version of the manuscript and A. Blomenkamp for excellent technical assistance.
  Supported by the Deutsche Forschungsgemeinschaft Sonderforschungsbereich 505/C5
  and Human Frontiers Science Program Organization Grant RG0017/98.
article_processing_charge: No
article_type: original
author:
- first_name: Henrik
  full_name: Alle, Henrik
  last_name: Alle
- first_name: Peter M
  full_name: Jonas, Peter M
  id: 353C1B58-F248-11E8-B48F-1D18A9856A87
  last_name: Jonas
  orcid: 0000-0001-5001-4804
- first_name: Jörg
  full_name: Geiger, Jörg
  last_name: Geiger
citation:
  ama: Alle H, Jonas PM, Geiger J. PTP and LTP at a hippocampal mossy fiber-interneuron
    synapse. <i>PNAS</i>. 2001;98(25):14708-14713. doi:<a href="https://doi.org/10.1073/pnas.251610898
    ">10.1073/pnas.251610898 </a>
  apa: Alle, H., Jonas, P. M., &#38; Geiger, J. (2001). PTP and LTP at a hippocampal
    mossy fiber-interneuron synapse. <i>PNAS</i>. National Academy of Sciences. <a
    href="https://doi.org/10.1073/pnas.251610898 ">https://doi.org/10.1073/pnas.251610898
    </a>
  chicago: Alle, Henrik, Peter M Jonas, and Jörg Geiger. “PTP and LTP at a Hippocampal
    Mossy Fiber-Interneuron Synapse.” <i>PNAS</i>. National Academy of Sciences, 2001.
    <a href="https://doi.org/10.1073/pnas.251610898 ">https://doi.org/10.1073/pnas.251610898
    </a>.
  ieee: H. Alle, P. M. Jonas, and J. Geiger, “PTP and LTP at a hippocampal mossy fiber-interneuron
    synapse,” <i>PNAS</i>, vol. 98, no. 25. National Academy of Sciences, pp. 14708–14713,
    2001.
  ista: Alle H, Jonas PM, Geiger J. 2001. PTP and LTP at a hippocampal mossy fiber-interneuron
    synapse. PNAS. 98(25), 14708–14713.
  mla: Alle, Henrik, et al. “PTP and LTP at a Hippocampal Mossy Fiber-Interneuron
    Synapse.” <i>PNAS</i>, vol. 98, no. 25, National Academy of Sciences, 2001, pp.
    14708–13, doi:<a href="https://doi.org/10.1073/pnas.251610898 ">10.1073/pnas.251610898
    </a>.
  short: H. Alle, P.M. Jonas, J. Geiger, PNAS 98 (2001) 14708–14713.
date_created: 2018-12-11T12:03:38Z
date_published: 2001-12-04T00:00:00Z
date_updated: 2023-05-15T11:08:08Z
day: '04'
doi: '10.1073/pnas.251610898 '
extern: '1'
external_id:
  pmid:
  - '11734656'
intvolume: '        98'
issue: '25'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC64746/
month: '12'
oa: 1
oa_version: None
page: 14708 - 14713
pmid: 1
publication: PNAS
publication_identifier:
  issn:
  - 0027-8424
publication_status: published
publisher: National Academy of Sciences
publist_id: '2891'
quality_controlled: '1'
scopus_import: '1'
status: public
title: PTP and LTP at a hippocampal mossy fiber-interneuron synapse
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 98
year: '2001'
...
---
_id: '3507'
abstract:
- lang: eng
  text: A molecular classification method is based on a space filling description
    of a molecule. The three dimensional body corresponding to the space filling molecular
    structure is divided into Voronoi regions to provide a basis for efficiently processing
    local structural information. A Delaunay triangulation provides a basis for systematically
    processing information relating to the Voronoi regions into shape descriptors
    in the form of topological elements. Preferably, additional shape and/or property
    descriptors are included in the classification method. The classification methods
    generally are used to identify similarities between molecules that can be used
    as property predictors for a variety of applications. Generally, the property
    predictions are the basis for selection of compounds for incorporation into efficacy
    evaluations.
applicant:
- Jie Liang, Herbert Edelsbrunner
article_processing_charge: No
author:
- first_name: Jie
  full_name: Liang, Jie
  last_name: Liang
- first_name: Herbert
  full_name: Edelsbrunner, Herbert
  id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
  last_name: Edelsbrunner
  orcid: 0000-0002-9823-6833
citation:
  ama: Liang J, Edelsbrunner H. Molecular classification for property prediction.
    2001.
  apa: Liang, J., &#38; Edelsbrunner, H. (2001). Molecular classification for property
    prediction.
  chicago: Liang, Jie, and Herbert Edelsbrunner. “Molecular Classification for Property
    Prediction,” 2001.
  ieee: J. Liang and H. Edelsbrunner, “Molecular classification for property prediction.”
    2001.
  ista: Liang J, Edelsbrunner H. 2001. Molecular classification for property prediction.
  mla: Liang, Jie, and Herbert Edelsbrunner. <i>Molecular Classification for Property
    Prediction</i>. 2001.
  short: J. Liang, H. Edelsbrunner, (2001).
date_created: 2018-12-11T12:03:41Z
date_published: 2001-01-30T00:00:00Z
date_updated: 2022-01-05T15:12:42Z
day: '30'
extern: '1'
ipc: G16C20/70 ; G16B15/00
ipn: US6182016B1
main_file_link:
- open_access: '1'
  url: https://patents.google.com/patent/US6182016B1
month: '01'
oa: 1
oa_version: Published Version
publication_date: 2001-01-30
publist_id: '2880'
status: public
title: Molecular classification for property prediction
type: patent
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2001'
...
