---
_id: '3757'
abstract:
- lang: eng
text: A central problem in biology is determining how genes interact as parts of
functional networks. Creation and analysis of synthetic networks, composed of
well-characterized genetic elements, provide a framework for theoretical modeling.
Here, with the use of a combinatorial method, a library of networks with varying
connectivity was generated in Escherichia coli. These networks were composed of
genes encoding the transcriptional regulators Lacl, TetR, and lambda Cl, as well
as the corresponding promoters. They displayed phenotypic behaviors resembling
binary logical circuits, with two chemical “inputs” and a fluorescent protein
“output.” Within this simple system, diverse computational functions arose through
changes in network connectivity. Combinatorial synthesis provides an alternative
approach for studying biological networks, as well as an efficient method for
producing diverse phenotypes in vivo.
article_processing_charge: No
article_type: original
author:
- first_name: Calin C
full_name: Guet, Calin C
id: 47F8433E-F248-11E8-B48F-1D18A9856A87
last_name: Guet
orcid: 0000-0001-6220-2052
- first_name: Michael
full_name: Elowitz, Michael
last_name: Elowitz
- first_name: Weihong
full_name: Hsing, Weihong
last_name: Hsing
- first_name: Stanislas
full_name: Leibler, Stanislas
last_name: Leibler
citation:
ama: Guet CC, Elowitz M, Hsing W, Leibler S. Combinatorial synthesis of genetic
networks. Science. 2002;296(5572):1466-1470. doi:10.1126/science.1067407
apa: Guet, C. C., Elowitz, M., Hsing, W., & Leibler, S. (2002). Combinatorial
synthesis of genetic networks. Science. American Association for the Advancement
of Science. https://doi.org/10.1126/science.1067407
chicago: Guet, Calin C, Michael Elowitz, Weihong Hsing, and Stanislas Leibler. “Combinatorial
Synthesis of Genetic Networks.” Science. American Association for the Advancement
of Science, 2002. https://doi.org/10.1126/science.1067407.
ieee: C. C. Guet, M. Elowitz, W. Hsing, and S. Leibler, “Combinatorial synthesis
of genetic networks,” Science, vol. 296, no. 5572. American Association
for the Advancement of Science, pp. 1466–1470, 2002.
ista: Guet CC, Elowitz M, Hsing W, Leibler S. 2002. Combinatorial synthesis of genetic
networks. Science. 296(5572), 1466–1470.
mla: Guet, Calin C., et al. “Combinatorial Synthesis of Genetic Networks.” Science,
vol. 296, no. 5572, American Association for the Advancement of Science, 2002,
pp. 1466–70, doi:10.1126/science.1067407.
short: C.C. Guet, M. Elowitz, W. Hsing, S. Leibler, Science 296 (2002) 1466–1470.
date_created: 2018-12-11T12:05:00Z
date_published: 2002-05-24T00:00:00Z
date_updated: 2023-07-11T12:48:53Z
day: '24'
doi: 10.1126/science.1067407
extern: '1'
external_id:
pmid:
- '12029133'
intvolume: ' 296'
issue: '5572'
language:
- iso: eng
month: '05'
oa_version: None
page: 1466 - 1470
pmid: 1
publication: Science
publication_identifier:
issn:
- 0036-8075
publication_status: published
publisher: American Association for the Advancement of Science
publist_id: '2471'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Combinatorial synthesis of genetic networks
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 296
year: '2002'
...
---
_id: '3799'
abstract:
- lang: eng
text: 'GABAergic interneurones are diverse in their morphological and functional
properties. Perisomatic inhibitory cells show fast spiking during sustained current
injection, whereas dendritic inhibitory cells fire action potentials with lower
frequency. We examined functional and molecular properties of K(+) channels in
interneurones with horizontal dendrites in stratum oriens-alveus (OA) of the hippocampal
CA1 region, which mainly comprise somatostatin-positive dendritic inhibitory cells.
Voltage-gated K(+) currents in nucleated patches isolated from OA interneurones
consisted of three major components: a fast delayed rectifier K(+) current component
that was highly sensitive to external 4-aminopyridine (4-AP) and tetraethylammonium
(TEA) (half-maximal inhibitory concentrations < 0.1 mM for both blockers),
a slow delayed rectifier K(+) current component that was sensitive to high concentrations
of TEA, but insensitive to 4-AP, and a rapidly inactivating A-type K(+) current
component that was blocked by high concentrations of 4-AP, but resistant to TEA.
The relative contributions of these components to the macroscopic K(+) current
were estimated as 57 +/- 5, 25 +/- 6, and 19 +/- 2 %, respectively. Dendrotoxin,
a selective blocker of Kv1 channels had only minimal effects on K(+) currents
in nucleated patches. Coapplication of the membrane-permeant cAMP analogue 8-(4-chlorophenylthio)-adenosine
3'':5''-cyclic monophosphate (cpt-cAMP) and the phosphodiesterase blocker isobutyl-methylxanthine
(IBMX) resulted in a selective inhibition of the fast delayed rectifier K(+) current
component. This inhibition was absent in the presence of the protein kinase A
(PKA) inhibitor H-89, implying the involvement of PKA-mediated phosphorylation.
Single-cell reverse transcription-polymerase chain reaction (RT-PCR) analysis
revealed a high abundance of Kv3.2 mRNA in OA interneurones, whereas the expression
level of Kv3.1 mRNA was markedly lower. Similarly, RT-PCR analysis showed a high
abundance of Kv4.3 mRNA, whereas Kv4.2 mRNA was undetectable. This suggests that
the fast delayed rectifier K(+) current and the A-type K(+) current component
are mediated predominantly by homomeric Kv3.2 and Kv4.3 channels. Selective modulation
of Kv3.2 channels in OA interneurones by cAMP is likely to be an important factor
regulating the activity of dendritic inhibitory cells in principal neurone-interneurone
microcircuits.'
acknowledgement: We thank Drs J. Bischofberger, M. Heckmann, and I. Vida for critically
reading the manuscript, and A. Blomenkamp and K. Winterhalter for technical assistance.
This work was supported by a scholarship from the Deutscher Akademischer Austansch
dienst to C.-C. L., a Deutsche Forschungsgemeinschaft grant to P. J. (SFB 505/C5),
and the Alexander-von-Humboldt foundation.
article_processing_charge: No
article_type: original
author:
- first_name: Cheng
full_name: Lien, Cheng
last_name: Lien
- first_name: Marco
full_name: Martina, Marco
last_name: Martina
- first_name: Jobst
full_name: Schultz, Jobst
last_name: Schultz
- first_name: Heimo
full_name: Ehmke, Heimo
last_name: Ehmke
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
citation:
ama: Lien C, Martina M, Schultz J, Ehmke H, Jonas PM. Gating, modulation and subunit
composition of voltage-gated K(+) channels in dendritic inhibitory interneurones
of rat hippocampus. Journal of Physiology. 2002;538(Pt 2):405-419. doi:10.1113/jphysiol.2001.013066
apa: Lien, C., Martina, M., Schultz, J., Ehmke, H., & Jonas, P. M. (2002). Gating,
modulation and subunit composition of voltage-gated K(+) channels in dendritic
inhibitory interneurones of rat hippocampus. Journal of Physiology. Wiley-Blackwell.
https://doi.org/10.1113/jphysiol.2001.013066
chicago: Lien, Cheng, Marco Martina, Jobst Schultz, Heimo Ehmke, and Peter M Jonas.
“Gating, Modulation and Subunit Composition of Voltage-Gated K(+) Channels in
Dendritic Inhibitory Interneurones of Rat Hippocampus.” Journal of Physiology.
Wiley-Blackwell, 2002. https://doi.org/10.1113/jphysiol.2001.013066.
ieee: C. Lien, M. Martina, J. Schultz, H. Ehmke, and P. M. Jonas, “Gating, modulation
and subunit composition of voltage-gated K(+) channels in dendritic inhibitory
interneurones of rat hippocampus,” Journal of Physiology, vol. 538, no.
Pt 2. Wiley-Blackwell, pp. 405–419, 2002.
ista: Lien C, Martina M, Schultz J, Ehmke H, Jonas PM. 2002. Gating, modulation
and subunit composition of voltage-gated K(+) channels in dendritic inhibitory
interneurones of rat hippocampus. Journal of Physiology. 538(Pt 2), 405–419.
mla: Lien, Cheng, et al. “Gating, Modulation and Subunit Composition of Voltage-Gated
K(+) Channels in Dendritic Inhibitory Interneurones of Rat Hippocampus.” Journal
of Physiology, vol. 538, no. Pt 2, Wiley-Blackwell, 2002, pp. 405–19, doi:10.1113/jphysiol.2001.013066.
short: C. Lien, M. Martina, J. Schultz, H. Ehmke, P.M. Jonas, Journal of Physiology
538 (2002) 405–419.
date_created: 2018-12-11T12:05:14Z
date_published: 2002-01-01T00:00:00Z
date_updated: 2023-07-11T12:32:26Z
day: '01'
doi: 10.1113/jphysiol.2001.013066
extern: '1'
external_id:
pmid:
- '11790809'
intvolume: ' 538'
issue: Pt 2
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2290075/
month: '01'
oa: 1
oa_version: Published Version
page: 405 - 419
pmid: 1
publication: Journal of Physiology
publication_identifier:
issn:
- 0022-3751
publication_status: published
publisher: Wiley-Blackwell
publist_id: '2411'
quality_controlled: '1'
status: public
title: Gating, modulation and subunit composition of voltage-gated K(+) channels in
dendritic inhibitory interneurones of rat hippocampus
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 538
year: '2002'
...
---
_id: '3800'
abstract:
- lang: eng
text: Networks of GABAergic interneurons are of critical importance for the generation
of gamma frequency oscillations in the brain. To examine the underlying synaptic
mechanisms, we made paired recordings from "basket cells" (BCs) in different
subfields of hippocampal slices, using transgenic mice that express enhanced green
fluorescent protein (EGFP) under the control of the parvalbumin promoter. Unitary
inhibitory postsynaptic currents (IPSCs) showed large amplitude and fast time
course with mean amplitude-weighted decay time constants of 2.5, 1.2, and 1.8
ms in the dentate gyrus, and the cornu ammonis area 3 (CA3) and 1 (CA1), respectively
(33-34 degrees C). The decay of unitary IPSCs at BC-BC synapses was significantly
faster than that at BC-principal cell synapses, indicating target cell-specific
differences in IPSC kinetics. In addition, electrical coupling was found in a
subset of BC-BC pairs. To examine whether an interneuron network with fast inhibitory
synapses can act as a gamma frequency oscillator, we developed an interneuron
network model based on experimentally determined properties. In comparison to
previous interneuron network models, our model was able to generate oscillatory
activity with higher coherence over a broad range of frequencies (20-110 Hz).
In this model, high coherence and flexibility in frequency control emerge from
the combination of synaptic properties, network structure, and electrical coupling.
acknowledgement: We thank Drs. J. Bischofberger, M. Heckmann, and R. Traub for critically
reading the manuscript. This work was supported by Deutsche Forschungsgemeinschaft
Grants SFB 505/C5 (to P.J.) and SFB 505/C6 (to M.F. and P.J.), Human Frontiers Science
Program Organization Grant RG0017/1998-B (to P.J.), and grants from the Alexander-von-Humboldt
Foundation (to P.J. and M.F.), the Schilling Foundation (to H.M.), and Novartis
(to H.M.).
article_processing_charge: No
article_type: original
author:
- first_name: Marlene
full_name: Bartos, Marlene
last_name: Bartos
- first_name: Imre
full_name: Vida, Imre
last_name: Vida
- first_name: Michael
full_name: Frotscher, Michael
last_name: Frotscher
- first_name: Axel
full_name: Meyer, Axel
last_name: Meyer
- first_name: Hannah
full_name: Monyer, Hannah
last_name: Monyer
- first_name: Jörg
full_name: Geiger, Jörg
last_name: Geiger
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
citation:
ama: Bartos M, Vida I, Frotscher M, et al. Fast synaptic inhibition promotes synchronized
gamma oscillations in hippocampal interneuron networks. PNAS. 2002;99(20):13222-13227.
doi:10.1073/pnas.192233099
apa: Bartos, M., Vida, I., Frotscher, M., Meyer, A., Monyer, H., Geiger, J., &
Jonas, P. M. (2002). Fast synaptic inhibition promotes synchronized gamma oscillations
in hippocampal interneuron networks. PNAS. National Academy of Sciences.
https://doi.org/10.1073/pnas.192233099
chicago: Bartos, Marlene, Imre Vida, Michael Frotscher, Axel Meyer, Hannah Monyer,
Jörg Geiger, and Peter M Jonas. “Fast Synaptic Inhibition Promotes Synchronized
Gamma Oscillations in Hippocampal Interneuron Networks.” PNAS. National
Academy of Sciences, 2002. https://doi.org/10.1073/pnas.192233099.
ieee: M. Bartos et al., “Fast synaptic inhibition promotes synchronized gamma
oscillations in hippocampal interneuron networks,” PNAS, vol. 99, no. 20.
National Academy of Sciences, pp. 13222–13227, 2002.
ista: Bartos M, Vida I, Frotscher M, Meyer A, Monyer H, Geiger J, Jonas PM. 2002.
Fast synaptic inhibition promotes synchronized gamma oscillations in hippocampal
interneuron networks. PNAS. 99(20), 13222–13227.
mla: Bartos, Marlene, et al. “Fast Synaptic Inhibition Promotes Synchronized Gamma
Oscillations in Hippocampal Interneuron Networks.” PNAS, vol. 99, no. 20,
National Academy of Sciences, 2002, pp. 13222–27, doi:10.1073/pnas.192233099.
short: M. Bartos, I. Vida, M. Frotscher, A. Meyer, H. Monyer, J. Geiger, P.M. Jonas,
PNAS 99 (2002) 13222–13227.
date_created: 2018-12-11T12:05:14Z
date_published: 2002-09-16T00:00:00Z
date_updated: 2023-07-10T13:35:18Z
day: '16'
doi: 10.1073/pnas.192233099
extern: '1'
external_id:
pmid:
- '12235359'
intvolume: ' 99'
issue: '20'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC130614/
month: '09'
oa: 1
oa_version: Published Version
page: 13222 - 13227
pmid: 1
publication: PNAS
publication_identifier:
issn:
- 0027-8424
publication_status: published
publisher: National Academy of Sciences
publist_id: '2409'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Fast synaptic inhibition promotes synchronized gamma oscillations in hippocampal
interneuron networks
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 99
year: '2002'
...
---
_id: '3801'
abstract:
- lang: eng
text: 'To examine possible interactions between fast depression and modulation of
inhibitory synaptic transmission in the hippocampus, we recorded from pairs of
synaptically connected basket cells (BCs) and granule cells (GCs) in the dentate
gyrus of rat brain slices at 34 degrees C. Multiple-pulse depression (MPD) was
examined in trains of 5 or 10 inhibitory postsynaptic currents (IPSCs) evoked
at frequencies of 10-100 Hz under several conditions that inhibit transmitter
release: block of voltage-dependent Ca2+ channels by Cd2+ (10 microM), activation
of gamma-amino-butyric acid type B receptors (GABA(B)Rs) by baclofen (10 microM)
and activation of muscarinic acetylcholine receptors (mAchRs) by carbachol (2
microM). All manipulations led to a substantial inhibition of synaptic transmission,
reducing the amplitude of the first IPSC in the train (IPSC1) by 72%, 61% and
29%, respectively. However, MPD was largely preserved under these conditions (0.34
in control versus 0.31, 0.50 and 0.47 in the respective conditions at 50 Hz).
Similarly, a theta burst stimulation (TBS) protocol reduced IPSC1 by 54%, but
left MPD unchanged (0.40 in control and 0.39 during TBS). Analysis of both fractions
of transmission failures and coefficients of variation (CV) of IPSC peak amplitudes
suggested that MPD had a presynaptic expression site, independent of release probability.
In conclusion, different types of presynaptic modulation of inhibitory synaptic
transmission converge on a reduction of synaptic strength, while short-term dynamics
are largely unchanged.'
acknowledgement: We thank Drs M. Bartos, J. Bischofberger, M. Heckmann and
I. Vida for critically reading the manuscript, Dr K. Götz for providing information about pharmacological properties of
inhibitory hippocampal synapses, and A. Blomenkamp and K. Winterhalter for
technical assistance. This work was supported by Deutsche Forschungsgemeinschaft
grants to P.J. (Jo-248/2-2,SFB 505/C5) and the Alexander-von-Humboldt foundation.
article_processing_charge: No
article_type: original
author:
- first_name: Stefan
full_name: Hefft, Stefan
last_name: Hefft
- first_name: Udo
full_name: Kraushaar, Udo
last_name: Kraushaar
- first_name: Jörg
full_name: Geiger, Jörg
last_name: Geiger
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
citation:
ama: Hefft S, Kraushaar U, Geiger J, Jonas PM. Presynaptic short-term depression
is maintained during regulation of transmitter release at a GABAergic synapse
in rat hippocampus. Journal of Physiology. 2002;539(Pt 1):201-208. doi:10.1113/jphysiol.2001.013455
apa: Hefft, S., Kraushaar, U., Geiger, J., & Jonas, P. M. (2002). Presynaptic
short-term depression is maintained during regulation of transmitter release at
a GABAergic synapse in rat hippocampus. Journal of Physiology. Wiley-Blackwell.
https://doi.org/10.1113/jphysiol.2001.013455
chicago: Hefft, Stefan, Udo Kraushaar, Jörg Geiger, and Peter M Jonas. “Presynaptic
Short-Term Depression Is Maintained during Regulation of Transmitter Release at
a GABAergic Synapse in Rat Hippocampus.” Journal of Physiology. Wiley-Blackwell,
2002. https://doi.org/10.1113/jphysiol.2001.013455.
ieee: S. Hefft, U. Kraushaar, J. Geiger, and P. M. Jonas, “Presynaptic short-term
depression is maintained during regulation of transmitter release at a GABAergic
synapse in rat hippocampus,” Journal of Physiology, vol. 539, no. Pt 1.
Wiley-Blackwell, pp. 201–8, 2002.
ista: Hefft S, Kraushaar U, Geiger J, Jonas PM. 2002. Presynaptic short-term depression
is maintained during regulation of transmitter release at a GABAergic synapse
in rat hippocampus. Journal of Physiology. 539(Pt 1), 201–8.
mla: Hefft, Stefan, et al. “Presynaptic Short-Term Depression Is Maintained during
Regulation of Transmitter Release at a GABAergic Synapse in Rat Hippocampus.”
Journal of Physiology, vol. 539, no. Pt 1, Wiley-Blackwell, 2002, pp. 201–08,
doi:10.1113/jphysiol.2001.013455.
short: S. Hefft, U. Kraushaar, J. Geiger, P.M. Jonas, Journal of Physiology 539
(2002) 201–8.
date_created: 2018-12-11T12:05:15Z
date_published: 2002-02-01T00:00:00Z
date_updated: 2023-07-11T10:01:12Z
day: '01'
doi: 10.1113/jphysiol.2001.013455
extern: '1'
external_id:
pmid:
- '11850513'
intvolume: ' 539'
issue: Pt 1
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2290140/
month: '02'
oa: 1
oa_version: Published Version
page: 201 - 8
pmid: 1
publication: Journal of Physiology
publication_identifier:
issn:
- 0022-3751
publication_status: published
publisher: Wiley-Blackwell
publist_id: '2410'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Presynaptic short-term depression is maintained during regulation of transmitter
release at a GABAergic synapse in rat hippocampus
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 539
year: '2002'
...
---
_id: '3802'
abstract:
- lang: eng
text: The presynaptic Ca2+ signal is a key determinant of transmitter release at
chemical synapses. In cortical synaptic terminals, however, little is known about
the kinetic properties of the presynaptic Ca2+ channels. To investigate the timing
and magnitude of the presynaptic Ca2+ inflow, we performed whole-cell patch-clamp
recordings from mossy fiber boutons (MFBs) in rat hippocampus. MFBs showed large
high-voltage-activated Ca(2+) currents, with a maximal amplitude of approximately
100 pA at a membrane potential of 0 mV. Both activation and deactivation were
fast, with time constants in the submillisecond range at a temperature of approximately
23 degrees C. An MFB action potential (AP) applied as a voltage-clamp command
evoked a transient Ca2+ current with an average amplitude of approximately 170
pA and a half-duration of 580 microsec. A prepulse to +40 mV had only minimal
effects on the AP-evoked Ca2+ current, indicating that presynaptic APs open the
voltage-gated Ca2+ channels very effectively. On the basis of the experimental
data, we developed a kinetic model with four closed states and one open state,
linked by voltage-dependent rate constants. Simulations of the Ca2+ current could
reproduce the experimental data, including the large amplitude and rapid time
course of the current evoked by MFB APs. Furthermore, the simulations indicate
that the shape of the presynaptic AP and the gating kinetics of the Ca2+ channels
are tuned to produce a maximal Ca2+ influx during a minimal period of time. The
precise timing and high efficacy of Ca2+ channel activation at this cortical glutamatergic
synapse may be important for synchronous transmitter release and temporal information
processing.
acknowledgement: J.B. was supported by grants from the Deutsche Forschungsgemeinschaft
(Bi 642/1-2 and SFB 505/C9). We thank Dr. U. Kraushaar, Dr. S. Hefft, and C. Schmidt-Hieber
for critically reading this manuscript, F. Heyde for secretarial help, and A. Blomenkamp
and K. Winterhalter for technical assistance.
article_processing_charge: No
article_type: original
author:
- first_name: Josef
full_name: Bischofberger, Josef
last_name: Bischofberger
- first_name: Jörg
full_name: Geiger, Jörg
last_name: Geiger
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
citation:
ama: Bischofberger J, Geiger J, Jonas PM. Timing and efficacy of Ca(2+) channel
activation in hippocampal mossy fiber boutons. Journal of Neuroscience.
2002;22(24):10593-10602. doi:10.1523/JNEUROSCI.22-24-10593.2002
apa: Bischofberger, J., Geiger, J., & Jonas, P. M. (2002). Timing and efficacy
of Ca(2+) channel activation in hippocampal mossy fiber boutons. Journal of
Neuroscience. Society for Neuroscience. https://doi.org/10.1523/JNEUROSCI.22-24-10593.2002
chicago: Bischofberger, Josef, Jörg Geiger, and Peter M Jonas. “Timing and Efficacy
of Ca(2+) Channel Activation in Hippocampal Mossy Fiber Boutons.” Journal of
Neuroscience. Society for Neuroscience, 2002. https://doi.org/10.1523/JNEUROSCI.22-24-10593.2002.
ieee: J. Bischofberger, J. Geiger, and P. M. Jonas, “Timing and efficacy of Ca(2+)
channel activation in hippocampal mossy fiber boutons,” Journal of Neuroscience,
vol. 22, no. 24. Society for Neuroscience, pp. 10593–10602, 2002.
ista: Bischofberger J, Geiger J, Jonas PM. 2002. Timing and efficacy of Ca(2+) channel
activation in hippocampal mossy fiber boutons. Journal of Neuroscience. 22(24),
10593–10602.
mla: Bischofberger, Josef, et al. “Timing and Efficacy of Ca(2+) Channel Activation
in Hippocampal Mossy Fiber Boutons.” Journal of Neuroscience, vol. 22,
no. 24, Society for Neuroscience, 2002, pp. 10593–602, doi:10.1523/JNEUROSCI.22-24-10593.2002.
short: J. Bischofberger, J. Geiger, P.M. Jonas, Journal of Neuroscience 22 (2002)
10593–10602.
date_created: 2018-12-11T12:05:15Z
date_published: 2002-12-01T00:00:00Z
date_updated: 2023-06-13T13:19:45Z
day: '01'
doi: 10.1523/JNEUROSCI.22-24-10593.2002
extern: '1'
external_id:
pmid:
- '12486151'
intvolume: ' 22'
issue: '24'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6758411/
month: '12'
oa: 1
oa_version: Published Version
page: 10593 - 10602
pmid: 1
publication: Journal of Neuroscience
publication_identifier:
issn:
- 0270-6474
publication_status: published
publisher: Society for Neuroscience
publist_id: '2407'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Timing and efficacy of Ca(2+) channel activation in hippocampal mossy fiber
boutons
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 22
year: '2002'
...
---
_id: '3803'
abstract:
- lang: eng
text: Mossy fiber (MF) synapses are key stations for flow of information through
the hippocampal formation. A major component of the output of the MF system is
directed towards inhibitory interneurons. Recent studies have revealed that the
functional properties of MF-interneuron synapses differ substantially from those
of MF-CA3 pyramidal neuron synapses. Mossy-fiber-interneuron synapses in the stratum
lucidum represent a continuum of functional subtypes, in which the subunit composition
of postsynaptic AMPA receptors and NMDA receptors appears to be regulated in a
coordinated manner.
article_processing_charge: No
article_type: letter_note
author:
- first_name: Josef
full_name: Bischofberger, Josef
last_name: Bischofberger
- first_name: Peter M
full_name: Jonas, Peter M
id: 353C1B58-F248-11E8-B48F-1D18A9856A87
last_name: Jonas
orcid: 0000-0001-5001-4804
citation:
ama: 'Bischofberger J, Jonas PM. TwoB or not twoB: differential transmission at
glutamatergic mossy fiber-interneuron synapses in the hippocampus. Trends in
Neurosciences. 2002;25(12):600-603. doi:10.1016/S0166-2236(02)02259-2'
apa: 'Bischofberger, J., & Jonas, P. M. (2002). TwoB or not twoB: differential
transmission at glutamatergic mossy fiber-interneuron synapses in the hippocampus.
Trends in Neurosciences. Elsevier. https://doi.org/10.1016/S0166-2236(02)02259-2'
chicago: 'Bischofberger, Josef, and Peter M Jonas. “TwoB or Not TwoB: Differential
Transmission at Glutamatergic Mossy Fiber-Interneuron Synapses in the Hippocampus.”
Trends in Neurosciences. Elsevier, 2002. https://doi.org/10.1016/S0166-2236(02)02259-2.'
ieee: 'J. Bischofberger and P. M. Jonas, “TwoB or not twoB: differential transmission
at glutamatergic mossy fiber-interneuron synapses in the hippocampus,” Trends
in Neurosciences, vol. 25, no. 12. Elsevier, pp. 600–603, 2002.'
ista: 'Bischofberger J, Jonas PM. 2002. TwoB or not twoB: differential transmission
at glutamatergic mossy fiber-interneuron synapses in the hippocampus. Trends in
Neurosciences. 25(12), 600–603.'
mla: 'Bischofberger, Josef, and Peter M. Jonas. “TwoB or Not TwoB: Differential
Transmission at Glutamatergic Mossy Fiber-Interneuron Synapses in the Hippocampus.”
Trends in Neurosciences, vol. 25, no. 12, Elsevier, 2002, pp. 600–03, doi:10.1016/S0166-2236(02)02259-2.'
short: J. Bischofberger, P.M. Jonas, Trends in Neurosciences 25 (2002) 600–603.
date_created: 2018-12-11T12:05:15Z
date_published: 2002-12-01T00:00:00Z
date_updated: 2023-07-10T13:22:24Z
day: '01'
doi: 10.1016/S0166-2236(02)02259-2
extern: '1'
external_id:
pmid:
- '12446120'
intvolume: ' 25'
issue: '12'
language:
- iso: eng
month: '12'
oa_version: None
page: 600 - 603
pmid: 1
publication: Trends in Neurosciences
publication_identifier:
issn:
- 0166-2236
publication_status: published
publisher: Elsevier
publist_id: '2408'
quality_controlled: '1'
status: public
title: 'TwoB or not twoB: differential transmission at glutamatergic mossy fiber-interneuron
synapses in the hippocampus'
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 25
year: '2002'
...
---
_id: '3919'
abstract:
- lang: eng
text: Hamilton's concept of local mate competition (LMC) is the standard model to
explain female-biased sex ratios in solitary Hymenoptera. In social Hymenoptera,
however, LMC has remained controversial, mainly because manipulation of sex allocation
by workers in response to relatedness asymmetries is an additional powerful mechanism
of female bias. Furthermore, the predominant mating systems in the social insects
are thought to make LMC unlikely. Nevertheless, several species exist in which
dispersal of males is limited and mating occurs in the nest. Some of these species,
such as the ant Cardiocondyla obscurior, have evolved dimorphic males, with one
morph being specialized for dispersal and the other for fighting with nest-mate
males over access to females. Such life history, combining sociality and alternative
reproductive tactics in males, provides a unique opportunity to test the power
of LMC as a selective force leading to female-biased sex ratios in social Hymenoptera.
We show that, in concordance with LMC predictions, an experimental increase in
queen number leads to a shift in sex allocation in favour of non-dispersing males,
but does not influence the proportion of disperser males. Furthermore, we can
assign this change in sex allocation at the colony level to the queens and rule
out worker manipulation.
acknowledgement: 'We thank A. F. G. Bourke, J. J. Boomsma, S. Foitzik, M. Sixt,C.
Anderson and C. Schubart for improving the manuscript, and E. Sixt for ant illustrations (figure 2). This study was
funded by the DFG (Deutsche Forschungsgemeinschaft: He1623/7-2).'
article_processing_charge: No
article_type: original
author:
- first_name: Sylvia
full_name: Cremer, Sylvia
id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
last_name: Cremer
orcid: 0000-0002-2193-3868
- first_name: Jürgen
full_name: Heinze, Jürgen
last_name: Heinze
citation:
ama: 'Cremer S, Heinze J. Adaptive production of fighter males: queens of the ant
Cardiocondyla adjust the sex ratio under local mate competition. Proceedings
of the Royal Society of London Series B Biological Sciences. 2002;269(1489):417-422.
doi:10.1098/rspb.2001.1892'
apa: 'Cremer, S., & Heinze, J. (2002). Adaptive production of fighter males:
queens of the ant Cardiocondyla adjust the sex ratio under local mate competition.
Proceedings of the Royal Society of London Series B Biological Sciences.
Royal Society, The. https://doi.org/10.1098/rspb.2001.1892'
chicago: 'Cremer, Sylvia, and Jürgen Heinze. “Adaptive Production of Fighter Males:
Queens of the Ant Cardiocondyla Adjust the Sex Ratio under Local Mate Competition.”
Proceedings of the Royal Society of London Series B Biological Sciences.
Royal Society, The, 2002. https://doi.org/10.1098/rspb.2001.1892.'
ieee: 'S. Cremer and J. Heinze, “Adaptive production of fighter males: queens of
the ant Cardiocondyla adjust the sex ratio under local mate competition,” Proceedings
of the Royal Society of London Series B Biological Sciences, vol. 269, no.
1489. Royal Society, The, pp. 417–422, 2002.'
ista: 'Cremer S, Heinze J. 2002. Adaptive production of fighter males: queens of
the ant Cardiocondyla adjust the sex ratio under local mate competition. Proceedings
of the Royal Society of London Series B Biological Sciences. 269(1489), 417–422.'
mla: 'Cremer, Sylvia, and Jürgen Heinze. “Adaptive Production of Fighter Males:
Queens of the Ant Cardiocondyla Adjust the Sex Ratio under Local Mate Competition.”
Proceedings of the Royal Society of London Series B Biological Sciences,
vol. 269, no. 1489, Royal Society, The, 2002, pp. 417–22, doi:10.1098/rspb.2001.1892.'
short: S. Cremer, J. Heinze, Proceedings of the Royal Society of London Series B
Biological Sciences 269 (2002) 417–422.
date_created: 2018-12-11T12:05:53Z
date_published: 2002-02-22T00:00:00Z
date_updated: 2023-06-13T11:52:17Z
day: '22'
doi: 10.1098/rspb.2001.1892
extern: '1'
external_id:
pmid:
- '11886631'
intvolume: ' 269'
issue: '1489'
language:
- iso: eng
main_file_link:
- open_access: '1'
url: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1690910/
month: '02'
oa: 1
oa_version: None
page: 417 - 422
pmid: 1
publication: Proceedings of the Royal Society of London Series B Biological Sciences
publication_identifier:
issn:
- 0962-8452
publication_status: published
publisher: Royal Society, The
publist_id: '2231'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Adaptive production of fighter males: queens of the ant Cardiocondyla adjust
the sex ratio under local mate competition'
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 269
year: '2002'
...
---
_id: '3920'
abstract:
- lang: eng
text: A particular Solid Injector needle, suitable for GC-MS analyses of small specimens,
is described together with its application in a study on ants.
acknowledgement: "We thank Giancarlo Bucelli and Gloriano Moneti (Centro Interdipartimentale\r\ndi
Spettrometria di Massa, Università di Firenze) for their help. Funding was\r\nprovided
by the MURST “60%” and Italian CNR “40%” funds, as well as through\r\nthe research
network “Social evolution” of the Universities of Aarhus, Firenze,\r\nKeele, Sheffield,
Uppsala, Würzburg and the ETH of Zürich financed by the\r\nEuropean commission via
the Training and Mobility of Researchers (TMR)\r\nprogramme. "
article_processing_charge: No
article_type: original
author:
- first_name: Stefano
full_name: Turillazzi, Stefano
last_name: Turillazzi
- first_name: Matthew
full_name: Sledge, Matthew
last_name: Sledge
- first_name: Sylvia
full_name: Cremer, Sylvia
id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
last_name: Cremer
orcid: 0000-0002-2193-3868
- first_name: Jürgen
full_name: Heinze, Jürgen
last_name: Heinze
citation:
ama: Turillazzi S, Sledge M, Cremer S, Heinze J. A method for analysing small-size
specimens in GC-MS. Insect Social Life. 2002;4:169-175.
apa: Turillazzi, S., Sledge, M., Cremer, S., & Heinze, J. (2002). A method for
analysing small-size specimens in GC-MS. Insect Social Life. Elsevier.
chicago: Turillazzi, Stefano, Matthew Sledge, Sylvia Cremer, and Jürgen Heinze.
“A Method for Analysing Small-Size Specimens in GC-MS.” Insect Social Life.
Elsevier, 2002.
ieee: S. Turillazzi, M. Sledge, S. Cremer, and J. Heinze, “A method for analysing
small-size specimens in GC-MS,” Insect Social Life, vol. 4. Elsevier, pp.
169–175, 2002.
ista: Turillazzi S, Sledge M, Cremer S, Heinze J. 2002. A method for analysing small-size
specimens in GC-MS. Insect Social Life. 4, 169–175.
mla: Turillazzi, Stefano, et al. “A Method for Analysing Small-Size Specimens in
GC-MS.” Insect Social Life, vol. 4, Elsevier, 2002, pp. 169–75.
short: S. Turillazzi, M. Sledge, S. Cremer, J. Heinze, Insect Social Life 4 (2002)
169–175.
date_created: 2018-12-11T12:05:54Z
date_published: 2002-01-01T00:00:00Z
date_updated: 2023-06-13T12:57:06Z
day: '01'
extern: '1'
intvolume: ' 4'
language:
- iso: eng
month: '01'
oa_version: None
page: 169 - 175
publication: Insect Social Life
publication_status: published
publisher: Elsevier
publist_id: '2232'
quality_controlled: '1'
status: public
title: A method for analysing small-size specimens in GC-MS
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 4
year: '2002'
...
---
_id: '3924'
abstract:
- lang: eng
text: 'Males of the ant Cardiocondyla show a dispersal dimorphism of a winged and
wingless morph. The loss of flight has lead to morphological reductions in the
wingless (ergatoid) males and also affected body size, eye size and pigmentation.
As ergatoid males mate exclusively inside the maternal nest, they underlie increased
male-male competition and therefore have also evolved additional changes in behaviour
and physiology: in contrast to winged males, ergatoid males are highly aggressive
towards each other and their spermatogenesis is prolonged compared to all other
hymenopteran males. In addition to these two male morphs, we found males with
an intermediate appearance. These "intermorphic" males provide a transitional
stage between normal males in most investigated morphological and physiological
parameters. As they are produced extremely rarely and only in colonies that switch
between pure ergatoid to mixed male production, we argue that they likely represent
a developmental mistake. Parallels between the determination of male morphs and
female castes (queen-worker dimorphism and worker polymorphism) might help to
understand how the large potential of phenotypic plasticity in both sexes of social
insects is realised during development.'
acknowledgement: We would like to thank S. Karpeles for histological analysis of the
winged males and S. Buchhauser for help with the photographs. This study was funded
by the DFG (grant He1623/12–1).
article_processing_charge: No
article_type: original
author:
- first_name: Sylvia
full_name: Cremer, Sylvia
id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
last_name: Cremer
orcid: 0000-0002-2193-3868
- first_name: Birgit
full_name: Lautenschläger, Birgit
last_name: Lautenschläger
- first_name: Jürgen
full_name: Heinze, Jürgen
last_name: Heinze
citation:
ama: Cremer S, Lautenschläger B, Heinze J. A transitional stage between the ergatoid
and winged male morph in the ant Cardiocondyla obscurior. Insectes Sociaux.
2002;49(3):221-228. doi:10.1007/s00040-002-8305-z
apa: Cremer, S., Lautenschläger, B., & Heinze, J. (2002). A transitional stage
between the ergatoid and winged male morph in the ant Cardiocondyla obscurior.
Insectes Sociaux. Springer. https://doi.org/10.1007/s00040-002-8305-z
chicago: Cremer, Sylvia, Birgit Lautenschläger, and Jürgen Heinze. “A Transitional
Stage between the Ergatoid and Winged Male Morph in the Ant Cardiocondyla Obscurior.”
Insectes Sociaux. Springer, 2002. https://doi.org/10.1007/s00040-002-8305-z.
ieee: S. Cremer, B. Lautenschläger, and J. Heinze, “A transitional stage between
the ergatoid and winged male morph in the ant Cardiocondyla obscurior,” Insectes
Sociaux, vol. 49, no. 3. Springer, pp. 221–228, 2002.
ista: Cremer S, Lautenschläger B, Heinze J. 2002. A transitional stage between the
ergatoid and winged male morph in the ant Cardiocondyla obscurior. Insectes Sociaux.
49(3), 221–228.
mla: Cremer, Sylvia, et al. “A Transitional Stage between the Ergatoid and Winged
Male Morph in the Ant Cardiocondyla Obscurior.” Insectes Sociaux, vol.
49, no. 3, Springer, 2002, pp. 221–28, doi:10.1007/s00040-002-8305-z.
short: S. Cremer, B. Lautenschläger, J. Heinze, Insectes Sociaux 49 (2002) 221–228.
date_created: 2018-12-11T12:05:55Z
date_published: 2002-04-05T00:00:00Z
date_updated: 2023-06-13T11:44:08Z
day: '05'
doi: 10.1007/s00040-002-8305-z
extern: '1'
intvolume: ' 49'
issue: '3'
language:
- iso: eng
month: '04'
oa_version: None
page: 221 - 228
publication: Insectes Sociaux
publication_identifier:
issn:
- 0020-1812
publication_status: published
publisher: Springer
publist_id: '2229'
quality_controlled: '1'
scopus_import: '1'
status: public
title: A transitional stage between the ergatoid and winged male morph in the ant
Cardiocondyla obscurior
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 49
year: '2002'
...
---
_id: '3925'
abstract:
- lang: eng
text: Males of the tropical ant Cardiocondyla obscurior are either wingless and
aggressive or winged and docile, and both compete for access to virgin queens
in the nest1, 2. Although the fighter males (ergatoids) attack and kill other
ergatoids, they tolerate and even attempt to mate with their winged rivals. Here
we show that the winged males avoid the aggression of wingless males by mimicking
the chemical bouquet of virgin queens, but that their mating success is not reduced
as a result. This example of female mimicry by vigorous males is surprising, as
in other species it is typically used as a protective strategy by weaker males,
and may explain the coexistence and equal mating success of two male morphs.
article_processing_charge: No
article_type: original
author:
- first_name: Sylvia
full_name: Cremer, Sylvia
id: 2F64EC8C-F248-11E8-B48F-1D18A9856A87
last_name: Cremer
orcid: 0000-0002-2193-3868
- first_name: Matthew
full_name: Sledge, Matthew
last_name: Sledge
- first_name: Jürgen
full_name: Heinze, Jürgen
last_name: Heinze
citation:
ama: 'Cremer S, Sledge M, Heinze J. Chemical mimicry: Male ants disguised by the
queen’s bouquet. Nature. 2002;419:897-897. doi:10.1038/419897a'
apa: 'Cremer, S., Sledge, M., & Heinze, J. (2002). Chemical mimicry: Male ants
disguised by the queen’s bouquet. Nature. Nature Publishing Group. https://doi.org/10.1038/419897a'
chicago: 'Cremer, Sylvia, Matthew Sledge, and Jürgen Heinze. “Chemical Mimicry:
Male Ants Disguised by the Queen’s Bouquet.” Nature. Nature Publishing
Group, 2002. https://doi.org/10.1038/419897a.'
ieee: 'S. Cremer, M. Sledge, and J. Heinze, “Chemical mimicry: Male ants disguised
by the queen’s bouquet,” Nature, vol. 419. Nature Publishing Group, pp.
897–897, 2002.'
ista: 'Cremer S, Sledge M, Heinze J. 2002. Chemical mimicry: Male ants disguised
by the queen’s bouquet. Nature. 419, 897–897.'
mla: 'Cremer, Sylvia, et al. “Chemical Mimicry: Male Ants Disguised by the Queen’s
Bouquet.” Nature, vol. 419, Nature Publishing Group, 2002, pp. 897–897,
doi:10.1038/419897a.'
short: S. Cremer, M. Sledge, J. Heinze, Nature 419 (2002) 897–897.
date_created: 2018-12-11T12:05:55Z
date_published: 2002-10-31T00:00:00Z
date_updated: 2023-06-13T11:47:19Z
day: '31'
doi: 10.1038/419897a
extern: '1'
external_id:
pmid:
- '12410300'
intvolume: ' 419'
language:
- iso: eng
month: '10'
oa_version: None
page: 897 - 897
pmid: 1
publication: Nature
publication_identifier:
issn:
- 0028-0836
publication_status: published
publisher: Nature Publishing Group
publist_id: '2230'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Chemical mimicry: Male ants disguised by the queen''s bouquet'
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 419
year: '2002'
...
---
_id: '3995'
abstract:
- lang: eng
text: This article is a survey of research areas in which motion plays a pivotal
role. The aim of the article is to review current approaches to modeling motion
together with related data structures and algorithms, and to summarize the challenges
that lie ahead in producing a more unified theory of motion representation that
would be useful across several disciplines.
acknowledgement: "This article is based on the report of the Workshop on Algorithmic
Issues in Modeling Motion, sponsored\r\nby an NSF grant CCR-00-83-033 and an Army
Research Office grant DAAD 19-00-1-0478, held on August 6\r\nand 7, 2000 at Duke
University, Durham, NC."
article_processing_charge: No
article_type: original
author:
- first_name: Pankaj
full_name: Agarwal, Pankaj
last_name: Agarwal
- first_name: Leonidas
full_name: Guibas, Leonidas
last_name: Guibas
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
- first_name: Jeff
full_name: Erickson, Jeff
last_name: Erickson
- first_name: Michael
full_name: Isard, Michael
last_name: Isard
- first_name: Sariel
full_name: Har Peled, Sariel
last_name: Har Peled
- first_name: John
full_name: Hershberger, John
last_name: Hershberger
- first_name: Christian
full_name: Jensen, Christian
last_name: Jensen
- first_name: Lydia
full_name: Kavraki, Lydia
last_name: Kavraki
- first_name: Patrice
full_name: Koehl, Patrice
last_name: Koehl
- first_name: Ming
full_name: Lin, Ming
last_name: Lin
- first_name: Dinesh
full_name: Manocha, Dinesh
last_name: Manocha
- first_name: Dimitris
full_name: Metaxas, Dimitris
last_name: Metaxas
- first_name: Brian
full_name: Mirtich, Brian
last_name: Mirtich
- first_name: David
full_name: Mount, David
last_name: Mount
- first_name: Sankara
full_name: Muthukrishnan, Sankara
last_name: Muthukrishnan
- first_name: Dinesh
full_name: Pai, Dinesh
last_name: Pai
- first_name: Elisha
full_name: Sacks, Elisha
last_name: Sacks
- first_name: Jack
full_name: Snoeyink, Jack
last_name: Snoeyink
- first_name: Subhash
full_name: Suri, Subhash
last_name: Suri
- first_name: Ouri
full_name: Wolefson, Ouri
last_name: Wolefson
citation:
ama: Agarwal P, Guibas L, Edelsbrunner H, et al. Algorithmic issues in modeling
motion. ACM Computing Surveys. 2002;34(4):550-572. doi:10.1145/592642.592647
apa: Agarwal, P., Guibas, L., Edelsbrunner, H., Erickson, J., Isard, M., Har Peled,
S., … Wolefson, O. (2002). Algorithmic issues in modeling motion. ACM Computing
Surveys. ACM. https://doi.org/10.1145/592642.592647
chicago: Agarwal, Pankaj, Leonidas Guibas, Herbert Edelsbrunner, Jeff Erickson,
Michael Isard, Sariel Har Peled, John Hershberger, et al. “Algorithmic Issues
in Modeling Motion.” ACM Computing Surveys. ACM, 2002. https://doi.org/10.1145/592642.592647.
ieee: P. Agarwal et al., “Algorithmic issues in modeling motion,” ACM
Computing Surveys, vol. 34, no. 4. ACM, pp. 550–572, 2002.
ista: Agarwal P, Guibas L, Edelsbrunner H, Erickson J, Isard M, Har Peled S, Hershberger
J, Jensen C, Kavraki L, Koehl P, Lin M, Manocha D, Metaxas D, Mirtich B, Mount
D, Muthukrishnan S, Pai D, Sacks E, Snoeyink J, Suri S, Wolefson O. 2002. Algorithmic
issues in modeling motion. ACM Computing Surveys. 34(4), 550–572.
mla: Agarwal, Pankaj, et al. “Algorithmic Issues in Modeling Motion.” ACM Computing
Surveys, vol. 34, no. 4, ACM, 2002, pp. 550–72, doi:10.1145/592642.592647.
short: P. Agarwal, L. Guibas, H. Edelsbrunner, J. Erickson, M. Isard, S. Har Peled,
J. Hershberger, C. Jensen, L. Kavraki, P. Koehl, M. Lin, D. Manocha, D. Metaxas,
B. Mirtich, D. Mount, S. Muthukrishnan, D. Pai, E. Sacks, J. Snoeyink, S. Suri,
O. Wolefson, ACM Computing Surveys 34 (2002) 550–572.
date_created: 2018-12-11T12:06:20Z
date_published: 2002-12-01T00:00:00Z
date_updated: 2023-06-13T11:34:25Z
day: '01'
doi: 10.1145/592642.592647
extern: '1'
intvolume: ' 34'
issue: '4'
language:
- iso: eng
month: '12'
oa_version: None
page: 550 - 572
publication: ACM Computing Surveys
publication_identifier:
issn:
- 0360-0300
publication_status: published
publisher: ACM
publist_id: '2129'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Algorithmic issues in modeling motion
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 34
year: '2002'
...
---
_id: '3996'
abstract:
- lang: eng
text: We formalize a notion of topological simplification within the framework of
a filtration, which is the history of a growing complex. We classify a topological
change that happens during growth as either a feature or noise depending on its
lifetime or persistence within the filtration. We give fast algorithms for computing
persistence and experimental evidence for their speed and utility.
acknowledgement: "We thank Jeff Erickson and John Harer for helpful discussions during
early stages of this\r\npaper. We also thank Daniel Huson for the zeolite dataset
Z, Thomas LaBean for the DNA\r\ndataset D, and the Stanford Graphics Lab for the
Buddha dataset S. To generate the bone\r\ndataset B, we sampled an iso-surface generated
by Dominique Attali. The volume data\r\nTopological Persistence and Simplification
533 was provided by Francoise Peyrin from CNRS CREATIS in Lyon and was issued from
¸ Synchrotron Radiation Microtomography from the ID19 beamline at ESRF in Grenoble.\r\nWe
generated Fig. 17 using the Protein Explorer [6]."
article_processing_charge: No
article_type: original
author:
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
- first_name: David
full_name: Letscher, David
last_name: Letscher
- first_name: Afra
full_name: Zomorodian, Afra
last_name: Zomorodian
citation:
ama: Edelsbrunner H, Letscher D, Zomorodian A. Topological persistence and simplification.
Discrete & Computational Geometry. 2002;28(4):511-533. doi:10.1007/s00454-002-2885-2
apa: Edelsbrunner, H., Letscher, D., & Zomorodian, A. (2002). Topological persistence
and simplification. Discrete & Computational Geometry. Springer. https://doi.org/10.1007/s00454-002-2885-2
chicago: Edelsbrunner, Herbert, David Letscher, and Afra Zomorodian. “Topological
Persistence and Simplification.” Discrete & Computational Geometry.
Springer, 2002. https://doi.org/10.1007/s00454-002-2885-2.
ieee: H. Edelsbrunner, D. Letscher, and A. Zomorodian, “Topological persistence
and simplification,” Discrete & Computational Geometry, vol. 28, no.
4. Springer, pp. 511–533, 2002.
ista: Edelsbrunner H, Letscher D, Zomorodian A. 2002. Topological persistence and
simplification. Discrete & Computational Geometry. 28(4), 511–533.
mla: Edelsbrunner, Herbert, et al. “Topological Persistence and Simplification.”
Discrete & Computational Geometry, vol. 28, no. 4, Springer, 2002,
pp. 511–33, doi:10.1007/s00454-002-2885-2.
short: H. Edelsbrunner, D. Letscher, A. Zomorodian, Discrete & Computational
Geometry 28 (2002) 511–533.
date_created: 2018-12-11T12:06:20Z
date_published: 2002-12-01T00:00:00Z
date_updated: 2023-06-13T11:41:19Z
day: '01'
doi: 10.1007/s00454-002-2885-2
extern: '1'
intvolume: ' 28'
issue: '4'
language:
- iso: eng
month: '12'
oa_version: None
page: 511 - 533
publication: Discrete & Computational Geometry
publication_identifier:
issn:
- 0179-5376
publication_status: published
publisher: Springer
publist_id: '2130'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Topological persistence and simplification
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 28
year: '2002'
...
---
_id: '3998'
abstract:
- lang: eng
text: We present results on a two-step improvement of mesh quality in three-dimensional
Delaunay triangulations. The first step refines the triangulation by inserting
sinks and eliminates tetrahedra with large circumradius over shortest edge length
ratio. The second step assigns weights to the vertices to eliminate slivers. Our
experimental findings provide evidence for the practical effectiveness of sliver
exudation.
acknowledgement: NSF under grants CCR-97-12088 and DMS 98-73945, NSF under grands
EIA-9972879 and CCR-00-86013 and by ARO under grant DAAG55-98-1- 0177.
article_processing_charge: No
article_type: original
author:
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
- first_name: Damrong
full_name: Guoy, Damrong
last_name: Guoy
citation:
ama: Edelsbrunner H, Guoy D. An experimental study of sliver exudation. Engineering
with Computers. 2002;18(3):229-240. doi:10.1007/s003660200020
apa: Edelsbrunner, H., & Guoy, D. (2002). An experimental study of sliver exudation.
Engineering with Computers. Springer. https://doi.org/10.1007/s003660200020
chicago: Edelsbrunner, Herbert, and Damrong Guoy. “An Experimental Study of Sliver
Exudation.” Engineering with Computers. Springer, 2002. https://doi.org/10.1007/s003660200020.
ieee: H. Edelsbrunner and D. Guoy, “An experimental study of sliver exudation,”
Engineering with Computers, vol. 18, no. 3. Springer, pp. 229–240, 2002.
ista: Edelsbrunner H, Guoy D. 2002. An experimental study of sliver exudation. Engineering
with Computers. 18(3), 229–240.
mla: Edelsbrunner, Herbert, and Damrong Guoy. “An Experimental Study of Sliver Exudation.”
Engineering with Computers, vol. 18, no. 3, Springer, 2002, pp. 229–40,
doi:10.1007/s003660200020.
short: H. Edelsbrunner, D. Guoy, Engineering with Computers 18 (2002) 229–240.
date_created: 2018-12-11T12:06:21Z
date_published: 2002-10-01T00:00:00Z
date_updated: 2023-06-13T11:14:44Z
day: '01'
doi: 10.1007/s003660200020
extern: '1'
intvolume: ' 18'
issue: '3'
language:
- iso: eng
month: '10'
oa_version: None
page: 229 - 240
publication: Engineering with Computers
publication_identifier:
issn:
- 0177-0667
publication_status: published
publisher: Springer
publist_id: '2126'
quality_controlled: '1'
scopus_import: '1'
status: public
title: An experimental study of sliver exudation
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 18
year: '2002'
...
---
_id: '4000'
abstract:
- lang: eng
text: We present fast implementations of a hybrid algorithm for reporting box and
cube intersections. Our algorithm initially takes a divide-and-conquer approach
and switches to simpler algorithms for low numbers of boxes. We use our implementations
as engines to solve problems about geometric primitives. We look at two such problems
in the category of quality analysis of surface triangulations.
acknowledgement: Center for Simulation of Advanced Rockets funded by the U.S. Department
of Energy under Subcontract B341494, NSF under grant CCR-96-19542 and ARO under
grant DAAG55-98-1-0177.
article_processing_charge: No
article_type: original
author:
- first_name: Afra
full_name: Zomorodian, Afra
last_name: Zomorodian
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
citation:
ama: Zomorodian A, Edelsbrunner H. Fast software for box intersections. International
Journal of Computational Geometry and Applications. 2002;12(1-2):143-172.
doi:10.1142/S0218195902000785
apa: Zomorodian, A., & Edelsbrunner, H. (2002). Fast software for box intersections.
International Journal of Computational Geometry and Applications. World
Scientific Publishing. https://doi.org/10.1142/S0218195902000785
chicago: Zomorodian, Afra, and Herbert Edelsbrunner. “Fast Software for Box Intersections.”
International Journal of Computational Geometry and Applications. World
Scientific Publishing, 2002. https://doi.org/10.1142/S0218195902000785.
ieee: A. Zomorodian and H. Edelsbrunner, “Fast software for box intersections,”
International Journal of Computational Geometry and Applications, vol.
12, no. 1–2. World Scientific Publishing, pp. 143–172, 2002.
ista: Zomorodian A, Edelsbrunner H. 2002. Fast software for box intersections. International
Journal of Computational Geometry and Applications. 12(1–2), 143–172.
mla: Zomorodian, Afra, and Herbert Edelsbrunner. “Fast Software for Box Intersections.”
International Journal of Computational Geometry and Applications, vol.
12, no. 1–2, World Scientific Publishing, 2002, pp. 143–72, doi:10.1142/S0218195902000785.
short: A. Zomorodian, H. Edelsbrunner, International Journal of Computational Geometry
and Applications 12 (2002) 143–172.
date_created: 2018-12-11T12:06:22Z
date_published: 2002-01-01T00:00:00Z
date_updated: 2023-06-13T11:20:09Z
day: '01'
doi: 10.1142/S0218195902000785
extern: '1'
intvolume: ' 12'
issue: 1-2
language:
- iso: eng
month: '01'
oa_version: None
page: 143 - 172
publication: International Journal of Computational Geometry and Applications
publication_identifier:
issn:
- 0218-1959
publication_status: published
publisher: World Scientific Publishing
publist_id: '2128'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Fast software for box intersections
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 12
year: '2002'
...
---
_id: '4003'
abstract:
- lang: eng
text: The writhing number measures the global geometry of a closed space curve or
knot. We show that this measure is related to the average winding number of its
Gauss map. Using this relationship, we give an algorithm for computing the writhing
number for a polygonal knot with n edges in time roughly proportional to n(1.6).
We also implement a different, simple algorithm and provide experimental evidence
for its practical efficiency.
acknowledgement: NSF under grants CCR-00-86013 and EIA-9972879, NSF under grant CCR-97-12088.
article_processing_charge: No
author:
- first_name: Pankaj
full_name: Agarwal, Pankaj
last_name: Agarwal
- first_name: Herbert
full_name: Edelsbrunner, Herbert
id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
last_name: Edelsbrunner
orcid: 0000-0002-9823-6833
- first_name: Yusu
full_name: Wang, Yusu
last_name: Wang
citation:
ama: 'Agarwal P, Edelsbrunner H, Wang Y. Computing the writhing number of a polygonal
knot. In: Proceedings of the 13th Annual ACM-SIAM Symposium on Discrete Algorithms.
SIAM; 2002:791-799.'
apa: 'Agarwal, P., Edelsbrunner, H., & Wang, Y. (2002). Computing the writhing
number of a polygonal knot. In Proceedings of the 13th annual ACM-SIAM symposium
on Discrete algorithms (pp. 791–799). San Francisco, CA, USA: SIAM.'
chicago: Agarwal, Pankaj, Herbert Edelsbrunner, and Yusu Wang. “Computing the Writhing
Number of a Polygonal Knot.” In Proceedings of the 13th Annual ACM-SIAM Symposium
on Discrete Algorithms, 791–99. SIAM, 2002.
ieee: P. Agarwal, H. Edelsbrunner, and Y. Wang, “Computing the writhing number of
a polygonal knot,” in Proceedings of the 13th annual ACM-SIAM symposium on
Discrete algorithms, San Francisco, CA, USA, 2002, pp. 791–799.
ista: 'Agarwal P, Edelsbrunner H, Wang Y. 2002. Computing the writhing number of
a polygonal knot. Proceedings of the 13th annual ACM-SIAM symposium on Discrete
algorithms. SODA: Symposium on Discrete Algorithms, 791–799.'
mla: Agarwal, Pankaj, et al. “Computing the Writhing Number of a Polygonal Knot.”
Proceedings of the 13th Annual ACM-SIAM Symposium on Discrete Algorithms,
SIAM, 2002, pp. 791–99.
short: P. Agarwal, H. Edelsbrunner, Y. Wang, in:, Proceedings of the 13th Annual
ACM-SIAM Symposium on Discrete Algorithms, SIAM, 2002, pp. 791–799.
conference:
end_date: 2002-01-08
location: San Francisco, CA, USA
name: 'SODA: Symposium on Discrete Algorithms'
start_date: 2002-01-06
date_created: 2018-12-11T12:06:23Z
date_published: 2002-01-01T00:00:00Z
date_updated: 2023-06-07T13:50:04Z
day: '01'
extern: '1'
language:
- iso: eng
main_file_link:
- url: https://dl.acm.org/doi/10.5555/545381.545485
month: '01'
oa_version: None
page: 791 - 799
publication: Proceedings of the 13th annual ACM-SIAM symposium on Discrete algorithms
publication_identifier:
isbn:
- '9780898715132'
publication_status: published
publisher: SIAM
publist_id: '2125'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Computing the writhing number of a polygonal knot
type: conference
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
year: '2002'
...
---
_id: '4139'
abstract:
- lang: eng
text: Pilot studies in England by Stopka and Macdonald revealed that allogrooming
in the Old World wood mouse, Apodemus sylvaticus, is a commodity that males can
trade for reproductive benefits with females. This study, which used a combination
of field study and observations in experimental enclosures, revealed that specific
experimental conditions such as group-size and sex-ratio manipulations have a
significant effect on the pattern of allogrooming exchanged between individuals.
Furthermore, females from the Czech population were more likely to associate with
each other as revealed by the clustering of activity centers of females (i.e.,
as opposed to almost exclusive ranges in English populations), and also by the
higher intensity of allogrooming exchanged between females (i.e., virtually lacking
in the previous experiment with English mice). Therefore, geographic variation
and specific social conditions seem to be important driving factors for allogrooming
behavior. Together with changes in overall grooming patterns, allogrooming between
males and females remained invariably asymmetrical over all four experimental
groups (i.e., two conditions for each sex) in that males provided more allogrooming
to females than they received from them.
article_processing_charge: No
article_type: original
author:
- first_name: Jitka
full_name: Polechova, Jitka
id: 3BBFB084-F248-11E8-B48F-1D18A9856A87
last_name: Polechova
orcid: 0000-0003-0951-3112
- first_name: P.
full_name: Stopka, P.
last_name: Stopka
citation:
ama: Polechova J, Stopka P. Geometry of social relationships in the Old World wood
mouse, Apodemus sylvaticus. Canadian Journal of Zoology. 2002;80(8):1383-1388.
doi:10.1139/z02-128
apa: Polechova, J., & Stopka, P. (2002). Geometry of social relationships in
the Old World wood mouse, Apodemus sylvaticus. Canadian Journal of Zoology.
NRC Research Press. https://doi.org/10.1139/z02-128
chicago: Polechova, Jitka, and P. Stopka. “Geometry of Social Relationships in the
Old World Wood Mouse, Apodemus Sylvaticus.” Canadian Journal of Zoology.
NRC Research Press, 2002. https://doi.org/10.1139/z02-128.
ieee: J. Polechova and P. Stopka, “Geometry of social relationships in the Old World
wood mouse, Apodemus sylvaticus,” Canadian Journal of Zoology, vol. 80,
no. 8. NRC Research Press, pp. 1383–1388, 2002.
ista: Polechova J, Stopka P. 2002. Geometry of social relationships in the Old World
wood mouse, Apodemus sylvaticus. Canadian Journal of Zoology. 80(8), 1383–1388.
mla: Polechova, Jitka, and P. Stopka. “Geometry of Social Relationships in the Old
World Wood Mouse, Apodemus Sylvaticus.” Canadian Journal of Zoology, vol.
80, no. 8, NRC Research Press, 2002, pp. 1383–88, doi:10.1139/z02-128.
short: J. Polechova, P. Stopka, Canadian Journal of Zoology 80 (2002) 1383–1388.
date_created: 2018-12-11T12:07:10Z
date_published: 2002-01-01T00:00:00Z
date_updated: 2023-06-07T12:53:35Z
day: '01'
doi: 10.1139/z02-128
extern: '1'
intvolume: ' 80'
issue: '8'
language:
- iso: eng
month: '01'
oa_version: None
page: 1383 - 1388
publication: Canadian Journal of Zoology
publication_identifier:
issn:
- 0008-4301
publication_status: published
publisher: NRC Research Press
publist_id: '1981'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Geometry of social relationships in the Old World wood mouse, Apodemus sylvaticus
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 80
year: '2002'
...
---
_id: '4148'
abstract:
- lang: eng
text: Members of the Wnt family have been implicated in a variety of developmental
processes including axis formation, Patterning of the central nervous system and
tissue morphogenesis. Recent studies have shown that a Wnt signalling pathway
similar to that involved in the establishment of planar cell polarity in Drosophila
regulates convergent extension movements during zebrafish and Xenopus gastrulation.
This finding provides a good starting point to dissect the complex cell biology
and genetic regulation of vertebrate gastrulation movements.
acknowledgement: We would like to thank Steve Wilson for encouraging us to write this
article and for critical comments on this manuscript, and Lila Solnica-Krezel for
communicating results prior to publication. MT is supported by an MRC Career Development
Award, MLC by a Wellcome Trust Fellowship and CPH by an Emmy–Noether–Fellowship
from the DFG.
article_processing_charge: No
article_type: original
author:
- first_name: Masazumi
full_name: Tada, Masazumi
last_name: Tada
- first_name: Miguel
full_name: Concha, Miguel
last_name: Concha
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
citation:
ama: Tada M, Concha M, Heisenberg C-PJ. Non-canonical Wnt signalling and regulation
of gastrulation movements. Seminars in Cell & Developmental Biology.
2002;13(3):251-260. doi:10.1016/S1084-9521(02)00052-6
apa: Tada, M., Concha, M., & Heisenberg, C.-P. J. (2002). Non-canonical Wnt
signalling and regulation of gastrulation movements. Seminars in Cell &
Developmental Biology. Academic Press. https://doi.org/10.1016/S1084-9521(02)00052-6
chicago: Tada, Masazumi, Miguel Concha, and Carl-Philipp J Heisenberg. “Non-Canonical
Wnt Signalling and Regulation of Gastrulation Movements.” Seminars in Cell
& Developmental Biology. Academic Press, 2002. https://doi.org/10.1016/S1084-9521(02)00052-6.
ieee: M. Tada, M. Concha, and C.-P. J. Heisenberg, “Non-canonical Wnt signalling
and regulation of gastrulation movements,” Seminars in Cell & Developmental
Biology, vol. 13, no. 3. Academic Press, pp. 251–260, 2002.
ista: Tada M, Concha M, Heisenberg C-PJ. 2002. Non-canonical Wnt signalling and
regulation of gastrulation movements. Seminars in Cell & Developmental Biology.
13(3), 251–260.
mla: Tada, Masazumi, et al. “Non-Canonical Wnt Signalling and Regulation of Gastrulation
Movements.” Seminars in Cell & Developmental Biology, vol. 13, no.
3, Academic Press, 2002, pp. 251–60, doi:10.1016/S1084-9521(02)00052-6.
short: M. Tada, M. Concha, C.-P.J. Heisenberg, Seminars in Cell & Developmental
Biology 13 (2002) 251–260.
date_created: 2018-12-11T12:07:13Z
date_published: 2002-06-01T00:00:00Z
date_updated: 2023-06-07T09:50:14Z
day: '01'
doi: 10.1016/S1084-9521(02)00052-6
extern: '1'
external_id:
pmid:
- '12137734'
intvolume: ' 13'
issue: '3'
language:
- iso: eng
month: '06'
oa_version: None
page: 251 - 260
pmid: 1
publication: Seminars in Cell & Developmental Biology
publication_identifier:
issn:
- 1084-9521
publication_status: published
publisher: Academic Press
publist_id: '1973'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Non-canonical Wnt signalling and regulation of gastrulation movements
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 13
year: '2002'
...
---
_id: '4194'
abstract:
- lang: eng
text: Cells at the anterior boundary of the neural plate (ANB) can induce telencephalic
gene expression when transplanted to more posterior regions. Here, we identify
a secreted Frizzled-related Wnt antagonist, Tic, that is expressed in ANB cells
and can cell nonautonomously promote telencephalic gene expression in a concentration-dependent
manner. Moreover, abrogation of Tlc function compromises telencephalic development.
We also identify Wnt8b as a locally acting modulator of regional fate in the anterior
neural plate and a likely target for antagonism by Tic. Finally, we show that
tlc expression is regulated by signals that establish early antero-posterior and
dorso-ventral ectodermal pattern. From these studies, we propose that local antagonism
of Wnt activity within the anterior ectoderm is required to establish the telencephalon.
acknowledgement: We thank many of our colleagues, especially Randy Moon, for providing reagents used
in this study. This study was supported by the Wellcome Trust, MRC, and BBSRC to
S.W.W. and C.H. S.W.W. is a Wellcome Trust Senior Research Fellow.
article_processing_charge: No
article_type: original
author:
- first_name: Corinne
full_name: Houart, Corinne
last_name: Houart
- first_name: Luca
full_name: Caneparo, Luca
last_name: Caneparo
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
- first_name: K Anukampa
full_name: Barth, K Anukampa
last_name: Barth
- first_name: Masaya
full_name: Take Uchi, Masaya
last_name: Take Uchi
- first_name: Stephen
full_name: Wilson, Stephen
last_name: Wilson
citation:
ama: Houart C, Caneparo L, Heisenberg C-PJ, Barth KA, Take Uchi M, Wilson S. Establishment
of the telencephalon during gastrulation by local antagonism of Wnt signaling.
Neuron. 2002;35(2):255-265. doi:10.1016/S0896-6273(02)00751-1
apa: Houart, C., Caneparo, L., Heisenberg, C.-P. J., Barth, K. A., Take Uchi, M.,
& Wilson, S. (2002). Establishment of the telencephalon during gastrulation
by local antagonism of Wnt signaling. Neuron. Elsevier. https://doi.org/10.1016/S0896-6273(02)00751-1
chicago: Houart, Corinne, Luca Caneparo, Carl-Philipp J Heisenberg, K Anukampa Barth,
Masaya Take Uchi, and Stephen Wilson. “Establishment of the Telencephalon during
Gastrulation by Local Antagonism of Wnt Signaling.” Neuron. Elsevier, 2002.
https://doi.org/10.1016/S0896-6273(02)00751-1.
ieee: C. Houart, L. Caneparo, C.-P. J. Heisenberg, K. A. Barth, M. Take Uchi, and
S. Wilson, “Establishment of the telencephalon during gastrulation by local antagonism
of Wnt signaling,” Neuron, vol. 35, no. 2. Elsevier, pp. 255–265, 2002.
ista: Houart C, Caneparo L, Heisenberg C-PJ, Barth KA, Take Uchi M, Wilson S. 2002.
Establishment of the telencephalon during gastrulation by local antagonism of
Wnt signaling. Neuron. 35(2), 255–265.
mla: Houart, Corinne, et al. “Establishment of the Telencephalon during Gastrulation
by Local Antagonism of Wnt Signaling.” Neuron, vol. 35, no. 2, Elsevier,
2002, pp. 255–65, doi:10.1016/S0896-6273(02)00751-1.
short: C. Houart, L. Caneparo, C.-P.J. Heisenberg, K.A. Barth, M. Take Uchi, S.
Wilson, Neuron 35 (2002) 255–265.
date_created: 2018-12-11T12:07:30Z
date_published: 2002-07-18T00:00:00Z
date_updated: 2023-06-07T09:43:19Z
day: '18'
doi: 10.1016/S0896-6273(02)00751-1
extern: '1'
external_id:
pmid:
- '12160744'
intvolume: ' 35'
issue: '2'
language:
- iso: eng
month: '07'
oa_version: None
page: 255 - 265
pmid: 1
publication: Neuron
publication_identifier:
issn:
- 0896-6273
publication_status: published
publisher: Elsevier
publist_id: '1925'
quality_controlled: '1'
scopus_import: '1'
status: public
title: Establishment of the telencephalon during gastrulation by local antagonism
of Wnt signaling
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 35
year: '2002'
...
---
_id: '4196'
abstract:
- lang: eng
text: During vertebrate gastrulation, large cellular rearrangements lead to the
formation of the three germ layers, ectoderm, mesoderm and endoderm. Zebrafish
offer many genetic and experimental advantages for studying vertebrate gastrulation
movements. For instance, several mutants, including silberblick, knypek and trilobite,
exhibit defects in morphogenesis during gastrulation. The identification of the
genes mutated in these lines together with the analysis of the mutant phenotypes
has provided new insights into the molecular and cellular mechanisms that underlie
vertebrate gastrulation movements.
acknowledgement: We would like to thank Miguel Concha, Will Norton, Tim Geach, Suzanne
Eaton, Kimbo Kotovic, Jenny Geiger and Steve Wilson for critical comments on this
manuscript, and Lila Solnica-Krezel for providing results prior to publication.
C.-P.H. is supported by an Emmy-Noether-Fellowship from the DFG and M.T. by an MRC
Career Development Award.
article_processing_charge: No
article_type: original
author:
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
- first_name: Masazumi
full_name: Tada, Masazumi
last_name: Tada
citation:
ama: 'Heisenberg C-PJ, Tada M. Zebrafish gastrulation movements: bridging cell and
developmental biology. Seminars in Cell & Developmental Biology. 2002;13(6):471-479.
doi:10.1016/S1084952102001003'
apa: 'Heisenberg, C.-P. J., & Tada, M. (2002). Zebrafish gastrulation movements:
bridging cell and developmental biology. Seminars in Cell & Developmental
Biology. Academic Press. https://doi.org/10.1016/S1084952102001003'
chicago: 'Heisenberg, Carl-Philipp J, and Masazumi Tada. “Zebrafish Gastrulation
Movements: Bridging Cell and Developmental Biology.” Seminars in Cell &
Developmental Biology. Academic Press, 2002. https://doi.org/10.1016/S1084952102001003.'
ieee: 'C.-P. J. Heisenberg and M. Tada, “Zebrafish gastrulation movements: bridging
cell and developmental biology,” Seminars in Cell & Developmental Biology,
vol. 13, no. 6. Academic Press, pp. 471–479, 2002.'
ista: 'Heisenberg C-PJ, Tada M. 2002. Zebrafish gastrulation movements: bridging
cell and developmental biology. Seminars in Cell & Developmental Biology.
13(6), 471–479.'
mla: 'Heisenberg, Carl-Philipp J., and Masazumi Tada. “Zebrafish Gastrulation Movements:
Bridging Cell and Developmental Biology.” Seminars in Cell & Developmental
Biology, vol. 13, no. 6, Academic Press, 2002, pp. 471–79, doi:10.1016/S1084952102001003.'
short: C.-P.J. Heisenberg, M. Tada, Seminars in Cell & Developmental Biology
13 (2002) 471–479.
date_created: 2018-12-11T12:07:31Z
date_published: 2002-12-01T00:00:00Z
date_updated: 2023-06-07T09:28:48Z
day: '01'
doi: 10.1016/S1084952102001003
extern: '1'
external_id:
pmid:
- '12468250'
intvolume: ' 13'
issue: '6'
language:
- iso: eng
month: '12'
oa_version: None
page: 471 - 479
pmid: 1
publication: Seminars in Cell & Developmental Biology
publication_identifier:
issn:
- 1084-9521
publication_status: published
publisher: Academic Press
publist_id: '1920'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Zebrafish gastrulation movements: bridging cell and developmental biology'
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 13
year: '2002'
...
---
_id: '4199'
abstract:
- lang: eng
text: Recent studies on vertebrate homologues of the van gogh/strabismus (vang/stbm)
gene, a key player in planar cell polarity signalling in Drosophila, show that
vang/stbm is involved in patterning and morphogenesis during vertebrate gastrulation
where it modulates two distinct Wnt signals.
article_processing_charge: No
article_type: original
author:
- first_name: Carl-Philipp J
full_name: Heisenberg, Carl-Philipp J
id: 39427864-F248-11E8-B48F-1D18A9856A87
last_name: Heisenberg
orcid: 0000-0002-0912-4566
- first_name: Masazumi
full_name: Tada, Masazumi
last_name: Tada
citation:
ama: 'Heisenberg C-PJ, Tada M. Wnt signalling: A moving picture emerges from van
gogh. Current Biology. 2002;12(4):R126-R128. doi:10.1016/S0960-9822(02)00704-2'
apa: 'Heisenberg, C.-P. J., & Tada, M. (2002). Wnt signalling: A moving picture
emerges from van gogh. Current Biology. Cell Press. https://doi.org/10.1016/S0960-9822(02)00704-2'
chicago: 'Heisenberg, Carl-Philipp J, and Masazumi Tada. “Wnt Signalling: A Moving
Picture Emerges from van Gogh.” Current Biology. Cell Press, 2002. https://doi.org/10.1016/S0960-9822(02)00704-2.'
ieee: 'C.-P. J. Heisenberg and M. Tada, “Wnt signalling: A moving picture emerges
from van gogh,” Current Biology, vol. 12, no. 4. Cell Press, pp. R126–R128,
2002.'
ista: 'Heisenberg C-PJ, Tada M. 2002. Wnt signalling: A moving picture emerges from
van gogh. Current Biology. 12(4), R126–R128.'
mla: 'Heisenberg, Carl-Philipp J., and Masazumi Tada. “Wnt Signalling: A Moving
Picture Emerges from van Gogh.” Current Biology, vol. 12, no. 4, Cell Press,
2002, pp. R126–28, doi:10.1016/S0960-9822(02)00704-2.'
short: C.-P.J. Heisenberg, M. Tada, Current Biology 12 (2002) R126–R128.
date_created: 2018-12-11T12:07:32Z
date_published: 2002-02-19T00:00:00Z
date_updated: 2023-06-07T08:54:35Z
day: '19'
doi: 10.1016/S0960-9822(02)00704-2
extern: '1'
external_id:
pmid:
- '11864583'
intvolume: ' 12'
issue: '4'
language:
- iso: eng
month: '02'
oa_version: None
page: R126 - R128
pmid: 1
publication: Current Biology
publication_identifier:
issn:
- 0960-9822
publication_status: published
publisher: Cell Press
publist_id: '1919'
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Wnt signalling: A moving picture emerges from van gogh'
type: journal_article
user_id: ea97e931-d5af-11eb-85d4-e6957dddbf17
volume: 12
year: '2002'
...