---
_id: '14314'
abstract:
- lang: eng
  text: The execution of cognitive functions requires coordinated circuit activity
    across different brain areas that involves the associated firing of neuronal assemblies.
    Here, we tested the circuit mechanism behind assembly interactions between the
    hippocampus and the medial prefrontal cortex (mPFC) of adult rats by recording
    neuronal populations during a rule-switching task. We identified functionally
    coupled CA1-mPFC cells that synchronized their activity beyond that expected from
    common spatial coding or oscillatory firing. When such cell pairs fired together,
    the mPFC cell strongly phase locked to CA1 theta oscillations and maintained consistent
    theta firing phases, independent of the theta timing of their CA1 counterpart.
    These functionally connected CA1-mPFC cells formed interconnected assemblies.
    While firing together with their CA1 assembly partners, mPFC cells fired along
    specific theta sequences. Our results suggest that upregulated theta oscillatory
    firing of mPFC cells can signal transient interactions with specific CA1 assemblies,
    thus enabling distributed computations.
acknowledgement: We thank A. Cumpelik, H. Chiossi, and L. Bollman for comments on
  an earlier version of this manuscript. This work was funded by EU-FP7 MC-ITN IN-SENS
  (grant 607616).
article_number: '113015'
article_processing_charge: Yes
article_type: original
author:
- first_name: Michele
  full_name: Nardin, Michele
  id: 30BD0376-F248-11E8-B48F-1D18A9856A87
  last_name: Nardin
  orcid: 0000-0001-8849-6570
- first_name: Karola
  full_name: Käfer, Karola
  id: 2DAA49AA-F248-11E8-B48F-1D18A9856A87
  last_name: Käfer
- first_name: Federico
  full_name: Stella, Federico
  id: 39AF1E74-F248-11E8-B48F-1D18A9856A87
  last_name: Stella
  orcid: 0000-0001-9439-3148
- first_name: Jozsef L
  full_name: Csicsvari, Jozsef L
  id: 3FA14672-F248-11E8-B48F-1D18A9856A87
  last_name: Csicsvari
  orcid: 0000-0002-5193-4036
citation:
  ama: Nardin M, Käfer K, Stella F, Csicsvari JL. Theta oscillations as a substrate
    for medial prefrontal-hippocampal assembly interactions. <i>Cell Reports</i>.
    2023;42(9). doi:<a href="https://doi.org/10.1016/j.celrep.2023.113015">10.1016/j.celrep.2023.113015</a>
  apa: Nardin, M., Käfer, K., Stella, F., &#38; Csicsvari, J. L. (2023). Theta oscillations
    as a substrate for medial prefrontal-hippocampal assembly interactions. <i>Cell
    Reports</i>. Elsevier. <a href="https://doi.org/10.1016/j.celrep.2023.113015">https://doi.org/10.1016/j.celrep.2023.113015</a>
  chicago: Nardin, Michele, Karola Käfer, Federico Stella, and Jozsef L Csicsvari.
    “Theta Oscillations as a Substrate for Medial Prefrontal-Hippocampal Assembly
    Interactions.” <i>Cell Reports</i>. Elsevier, 2023. <a href="https://doi.org/10.1016/j.celrep.2023.113015">https://doi.org/10.1016/j.celrep.2023.113015</a>.
  ieee: M. Nardin, K. Käfer, F. Stella, and J. L. Csicsvari, “Theta oscillations as
    a substrate for medial prefrontal-hippocampal assembly interactions,” <i>Cell
    Reports</i>, vol. 42, no. 9. Elsevier, 2023.
  ista: Nardin M, Käfer K, Stella F, Csicsvari JL. 2023. Theta oscillations as a substrate
    for medial prefrontal-hippocampal assembly interactions. Cell Reports. 42(9),
    113015.
  mla: Nardin, Michele, et al. “Theta Oscillations as a Substrate for Medial Prefrontal-Hippocampal
    Assembly Interactions.” <i>Cell Reports</i>, vol. 42, no. 9, 113015, Elsevier,
    2023, doi:<a href="https://doi.org/10.1016/j.celrep.2023.113015">10.1016/j.celrep.2023.113015</a>.
  short: M. Nardin, K. Käfer, F. Stella, J.L. Csicsvari, Cell Reports 42 (2023).
date_created: 2023-09-10T22:01:11Z
date_published: 2023-09-26T00:00:00Z
date_updated: 2023-09-15T07:14:12Z
day: '26'
ddc:
- '570'
department:
- _id: JoCs
doi: 10.1016/j.celrep.2023.113015
ec_funded: 1
external_id:
  pmid:
  - '37632747'
file:
- access_level: open_access
  checksum: ca77a304fb813c292550b8604b0fb41d
  content_type: application/pdf
  creator: dernst
  date_created: 2023-09-15T07:12:46Z
  date_updated: 2023-09-15T07:12:46Z
  file_id: '14337'
  file_name: 2023_CellPress_Nardin.pdf
  file_size: 4879455
  relation: main_file
  success: 1
file_date_updated: 2023-09-15T07:12:46Z
has_accepted_license: '1'
intvolume: '        42'
issue: '9'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 257BBB4C-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '607616'
  name: Inter-and intracellular signalling in schizophrenia
publication: Cell Reports
publication_identifier:
  eissn:
  - 2211-1247
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Theta oscillations as a substrate for medial prefrontal-hippocampal assembly
  interactions
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 42
year: '2023'
...
---
_id: '14315'
abstract:
- lang: eng
  text: During apoptosis, caspases degrade 8 out of ~30 nucleoporins to irreversibly
    demolish the nuclear pore complex. However, for poorly understood reasons, caspases
    are also activated during cell differentiation. Here, we show that sublethal activation
    of caspases during myogenesis results in the transient proteolysis of four peripheral
    Nups and one transmembrane Nup. ‘Trimmed’ NPCs become nuclear export-defective,
    and we identified in an unbiased manner several classes of cytoplasmic, plasma
    membrane, and mitochondrial proteins that rapidly accumulate in the nucleus. NPC
    trimming by non-apoptotic caspases was also observed in neurogenesis and endoplasmic
    reticulum stress. Our results suggest that caspases can reversibly modulate nuclear
    transport activity, which allows them to function as agents of cell differentiation
    and adaptation at sublethal levels.
acknowledgement: 'We thank the members of the Hetzer laboratory, Tony Hunter (Salk),
  Lorenzo Puri (Sanford Burnham Prebys), and Jongmin Kim (Massachusetts General Hospital)
  for the critical reading of the manuscript; Kenneth Diffenderfer and Aimee Pankonin
  (Stem Cell Core at the Salk Institute) for help with neurogenesis; Carol Marchetto
  and Fred Gage (Salk) for providing H9 embryonic stem cells; Lorenzo Puri, Alexandra
  Sacco, and Luca Caputo (Sanford Burnham Prebys) for helpful discussions and sharing
  mouse primary myoblasts. This work was supported by a Glenn Foundation for Medical
  Research Postdoctoral Fellowship in Aging Research (UHC), the NOMIS foundation (MWH),
  and the National Institutes of Health (R01 NS096786 to MWH and K01 AR080828 to UHC).
  This work was also supported by the Mass Spectrometry Core of the Salk Institute
  with funding from NIH-NCI CCSG: P30 014195 and the Helmsley Center for Genomic Medicine.
  We thank Jolene Diedrich and Antonio Pinto for technical support.'
article_number: RP89066
article_processing_charge: Yes
article_type: original
author:
- first_name: Ukrae H.
  full_name: Cho, Ukrae H.
  last_name: Cho
- first_name: Martin W
  full_name: Hetzer, Martin W
  id: 86c0d31b-b4eb-11ec-ac5a-eae7b2e135ed
  last_name: Hetzer
  orcid: 0000-0002-2111-992X
citation:
  ama: Cho UH, Hetzer M. Caspase-mediated nuclear pore complex trimming in cell differentiation
    and endoplasmic reticulum stress. <i>eLife</i>. 2023;12. doi:<a href="https://doi.org/10.7554/eLife.89066">10.7554/eLife.89066</a>
  apa: Cho, U. H., &#38; Hetzer, M. (2023). Caspase-mediated nuclear pore complex
    trimming in cell differentiation and endoplasmic reticulum stress. <i>ELife</i>.
    eLife Sciences Publications. <a href="https://doi.org/10.7554/eLife.89066">https://doi.org/10.7554/eLife.89066</a>
  chicago: Cho, Ukrae H., and Martin Hetzer. “Caspase-Mediated Nuclear Pore Complex
    Trimming in Cell Differentiation and Endoplasmic Reticulum Stress.” <i>ELife</i>.
    eLife Sciences Publications, 2023. <a href="https://doi.org/10.7554/eLife.89066">https://doi.org/10.7554/eLife.89066</a>.
  ieee: U. H. Cho and M. Hetzer, “Caspase-mediated nuclear pore complex trimming in
    cell differentiation and endoplasmic reticulum stress,” <i>eLife</i>, vol. 12.
    eLife Sciences Publications, 2023.
  ista: Cho UH, Hetzer M. 2023. Caspase-mediated nuclear pore complex trimming in
    cell differentiation and endoplasmic reticulum stress. eLife. 12, RP89066.
  mla: Cho, Ukrae H., and Martin Hetzer. “Caspase-Mediated Nuclear Pore Complex Trimming
    in Cell Differentiation and Endoplasmic Reticulum Stress.” <i>ELife</i>, vol.
    12, RP89066, eLife Sciences Publications, 2023, doi:<a href="https://doi.org/10.7554/eLife.89066">10.7554/eLife.89066</a>.
  short: U.H. Cho, M. Hetzer, ELife 12 (2023).
date_created: 2023-09-10T22:01:11Z
date_published: 2023-09-04T00:00:00Z
date_updated: 2023-09-15T07:07:10Z
day: '04'
ddc:
- '570'
department:
- _id: MaHe
doi: 10.7554/eLife.89066
external_id:
  pmid:
  - '37665327'
file:
- access_level: open_access
  checksum: db24bf3d595507387b48d3799c33e289
  content_type: application/pdf
  creator: dernst
  date_created: 2023-09-15T06:59:10Z
  date_updated: 2023-09-15T06:59:10Z
  file_id: '14336'
  file_name: 2023_eLife_Cho.pdf
  file_size: 3703097
  relation: main_file
  success: 1
file_date_updated: 2023-09-15T06:59:10Z
has_accepted_license: '1'
intvolume: '        12'
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
pmid: 1
publication: eLife
publication_identifier:
  eissn:
  - 2050-084X
publication_status: published
publisher: eLife Sciences Publications
quality_controlled: '1'
scopus_import: '1'
status: public
title: Caspase-mediated nuclear pore complex trimming in cell differentiation and
  endoplasmic reticulum stress
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 12
year: '2023'
...
---
_id: '14316'
abstract:
- lang: eng
  text: Clathrin-mediated vesicle trafficking plays central roles in post-Golgi transport.
    In yeast (Saccharomyces cerevisiae), the AP-1 complex and GGA adaptors are predicted
    to generate distinct transport vesicles at the trans-Golgi network (TGN), and
    the epsin-related proteins Ent3p and Ent5p (collectively Ent3p/5p) act as accessories
    for these adaptors. Recently, we showed that vesicle transport from the TGN is
    crucial for yeast Rab5 (Vps21p)-mediated endosome formation, and that Ent3p/5p
    are crucial for this process, whereas AP-1 and GGA adaptors are dispensable. However,
    these observations were incompatible with previous studies showing that these
    adaptors are required for Ent3p/5p recruitment to the TGN, and thus the overall
    mechanism responsible for regulation of Vps21p activity remains ambiguous. Here,
    we investigated the functional relationships between clathrin adaptors in post-Golgi-mediated
    Vps21p activation. We show that AP-1 disruption in the ent3Δ5Δ mutant impaired
    transport of the Vps21p guanine nucleotide exchange factor Vps9p transport to
    the Vps21p compartment and severely reduced Vps21p activity. Additionally, GGA
    adaptors, the phosphatidylinositol-4-kinase Pik1p and Rab11 GTPases Ypt31p and
    Ypt32p were found to have partially overlapping functions for recruitment of AP-1
    and Ent3p/5p to the TGN. These findings suggest a distinct role of clathrin adaptors
    for Vps21p activation in the TGN–endosome trafficking pathway.
article_number: jcs261448
article_processing_charge: No
article_type: original
author:
- first_name: Makoto
  full_name: Nagano, Makoto
  last_name: Nagano
- first_name: Kaito
  full_name: Aoshima, Kaito
  last_name: Aoshima
- first_name: Hiroki
  full_name: Shimamura, Hiroki
  last_name: Shimamura
- first_name: Daria E
  full_name: Siekhaus, Daria E
  id: 3D224B9E-F248-11E8-B48F-1D18A9856A87
  last_name: Siekhaus
  orcid: 0000-0001-8323-8353
- first_name: Junko Y.
  full_name: Toshima, Junko Y.
  last_name: Toshima
- first_name: Jiro
  full_name: Toshima, Jiro
  last_name: Toshima
citation:
  ama: Nagano M, Aoshima K, Shimamura H, Siekhaus DE, Toshima JY, Toshima J. Distinct
    role of TGN-resident clathrin adaptors for Vps21p activation in the TGN-endosome
    trafficking pathway. <i>Journal of Cell Science</i>. 2023;136(17). doi:<a href="https://doi.org/10.1242/jcs.261448">10.1242/jcs.261448</a>
  apa: Nagano, M., Aoshima, K., Shimamura, H., Siekhaus, D. E., Toshima, J. Y., &#38;
    Toshima, J. (2023). Distinct role of TGN-resident clathrin adaptors for Vps21p
    activation in the TGN-endosome trafficking pathway. <i>Journal of Cell Science</i>.
    The Company of Biologists. <a href="https://doi.org/10.1242/jcs.261448">https://doi.org/10.1242/jcs.261448</a>
  chicago: Nagano, Makoto, Kaito Aoshima, Hiroki Shimamura, Daria E Siekhaus, Junko
    Y. Toshima, and Jiro Toshima. “Distinct Role of TGN-Resident Clathrin Adaptors
    for Vps21p Activation in the TGN-Endosome Trafficking Pathway.” <i>Journal of
    Cell Science</i>. The Company of Biologists, 2023. <a href="https://doi.org/10.1242/jcs.261448">https://doi.org/10.1242/jcs.261448</a>.
  ieee: M. Nagano, K. Aoshima, H. Shimamura, D. E. Siekhaus, J. Y. Toshima, and J.
    Toshima, “Distinct role of TGN-resident clathrin adaptors for Vps21p activation
    in the TGN-endosome trafficking pathway,” <i>Journal of Cell Science</i>, vol.
    136, no. 17. The Company of Biologists, 2023.
  ista: Nagano M, Aoshima K, Shimamura H, Siekhaus DE, Toshima JY, Toshima J. 2023.
    Distinct role of TGN-resident clathrin adaptors for Vps21p activation in the TGN-endosome
    trafficking pathway. Journal of Cell Science. 136(17), jcs261448.
  mla: Nagano, Makoto, et al. “Distinct Role of TGN-Resident Clathrin Adaptors for
    Vps21p Activation in the TGN-Endosome Trafficking Pathway.” <i>Journal of Cell
    Science</i>, vol. 136, no. 17, jcs261448, The Company of Biologists, 2023, doi:<a
    href="https://doi.org/10.1242/jcs.261448">10.1242/jcs.261448</a>.
  short: M. Nagano, K. Aoshima, H. Shimamura, D.E. Siekhaus, J.Y. Toshima, J. Toshima,
    Journal of Cell Science 136 (2023).
date_created: 2023-09-10T22:01:12Z
date_published: 2023-09-01T00:00:00Z
date_updated: 2023-09-20T09:14:15Z
day: '01'
department:
- _id: DaSi
doi: 10.1242/jcs.261448
external_id:
  pmid:
  - '37539494'
intvolume: '       136'
issue: '17'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1101/2023.03.27.534325
month: '09'
oa: 1
oa_version: Preprint
pmid: 1
publication: Journal of Cell Science
publication_identifier:
  eissn:
  - 1477-9137
  issn:
  - 0021-9533
publication_status: published
publisher: The Company of Biologists
quality_controlled: '1'
scopus_import: '1'
status: public
title: Distinct role of TGN-resident clathrin adaptors for Vps21p activation in the
  TGN-endosome trafficking pathway
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 136
year: '2023'
...
---
_id: '14317'
abstract:
- lang: eng
  text: "Markov decision processes can be viewed as transformers of probability distributions.
    While this view is useful from a practical standpoint to reason about trajectories
    of distributions, basic reachability and safety problems are known to be computationally
    intractable (i.e., Skolem-hard) to solve in such models. Further, we show that
    even for simple examples of MDPs, strategies for safety objectives over distributions
    can require infinite memory and randomization.\r\nIn light of this, we present
    a novel overapproximation approach to synthesize strategies in an MDP, such that
    a safety objective over the distributions is met. More precisely, we develop a
    new framework for template-based synthesis of certificates as affine distributional
    and inductive invariants for safety objectives in MDPs. We provide two algorithms
    within this framework. One can only synthesize memoryless strategies, but has
    relative completeness guarantees, while the other can synthesize general strategies.
    The runtime complexity of both algorithms is in PSPACE. We implement these algorithms
    and show that they can solve several non-trivial examples."
acknowledgement: This work was supported in part by the ERC CoG 863818 (FoRM-SMArt)
  and the European Union’s Horizon 2020 research and innovation programme under the
  Marie Skłodowska-Curie Grant Agreement No. 665385 as well as DST/CEFIPRA/INRIA project
  EQuaVE and SERB Matrices grant MTR/2018/00074.
alternative_title:
- LNCS
article_processing_charge: Yes (in subscription journal)
author:
- first_name: S.
  full_name: Akshay, S.
  last_name: Akshay
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Tobias
  full_name: Meggendorfer, Tobias
  id: b21b0c15-30a2-11eb-80dc-f13ca25802e1
  last_name: Meggendorfer
  orcid: 0000-0002-1712-2165
- first_name: Dorde
  full_name: Zikelic, Dorde
  id: 294AA7A6-F248-11E8-B48F-1D18A9856A87
  last_name: Zikelic
  orcid: 0000-0002-4681-1699
citation:
  ama: 'Akshay S, Chatterjee K, Meggendorfer T, Zikelic D. MDPs as distribution transformers:
    Affine invariant synthesis for safety objectives. In: <i>International Conference
    on Computer Aided Verification</i>. Vol 13966. Springer Nature; 2023:86-112. doi:<a
    href="https://doi.org/10.1007/978-3-031-37709-9_5">10.1007/978-3-031-37709-9_5</a>'
  apa: 'Akshay, S., Chatterjee, K., Meggendorfer, T., &#38; Zikelic, D. (2023). MDPs
    as distribution transformers: Affine invariant synthesis for safety objectives.
    In <i>International Conference on Computer Aided Verification</i> (Vol. 13966,
    pp. 86–112). Paris, France: Springer Nature. <a href="https://doi.org/10.1007/978-3-031-37709-9_5">https://doi.org/10.1007/978-3-031-37709-9_5</a>'
  chicago: 'Akshay, S., Krishnendu Chatterjee, Tobias Meggendorfer, and Dorde Zikelic.
    “MDPs as Distribution Transformers: Affine Invariant Synthesis for Safety Objectives.”
    In <i>International Conference on Computer Aided Verification</i>, 13966:86–112.
    Springer Nature, 2023. <a href="https://doi.org/10.1007/978-3-031-37709-9_5">https://doi.org/10.1007/978-3-031-37709-9_5</a>.'
  ieee: 'S. Akshay, K. Chatterjee, T. Meggendorfer, and D. Zikelic, “MDPs as distribution
    transformers: Affine invariant synthesis for safety objectives,” in <i>International
    Conference on Computer Aided Verification</i>, Paris, France, 2023, vol. 13966,
    pp. 86–112.'
  ista: 'Akshay S, Chatterjee K, Meggendorfer T, Zikelic D. 2023. MDPs as distribution
    transformers: Affine invariant synthesis for safety objectives. International
    Conference on Computer Aided Verification. CAV: Computer Aided Verification, LNCS,
    vol. 13966, 86–112.'
  mla: 'Akshay, S., et al. “MDPs as Distribution Transformers: Affine Invariant Synthesis
    for Safety Objectives.” <i>International Conference on Computer Aided Verification</i>,
    vol. 13966, Springer Nature, 2023, pp. 86–112, doi:<a href="https://doi.org/10.1007/978-3-031-37709-9_5">10.1007/978-3-031-37709-9_5</a>.'
  short: S. Akshay, K. Chatterjee, T. Meggendorfer, D. Zikelic, in:, International
    Conference on Computer Aided Verification, Springer Nature, 2023, pp. 86–112.
conference:
  end_date: 2023-07-22
  location: Paris, France
  name: 'CAV: Computer Aided Verification'
  start_date: 2023-07-17
date_created: 2023-09-10T22:01:12Z
date_published: 2023-07-17T00:00:00Z
date_updated: 2025-07-14T09:09:56Z
day: '17'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.1007/978-3-031-37709-9_5
ec_funded: 1
file:
- access_level: open_access
  checksum: f143c8eedf609f20f2aad2eeb496d53f
  content_type: application/pdf
  creator: dernst
  date_created: 2023-09-20T08:46:43Z
  date_updated: 2023-09-20T08:46:43Z
  file_id: '14349'
  file_name: 2023_LNCS_Akshay.pdf
  file_size: 531745
  relation: main_file
  success: 1
file_date_updated: 2023-09-20T08:46:43Z
has_accepted_license: '1'
intvolume: '     13966'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: 86-112
project:
- _id: 2564DBCA-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '665385'
  name: International IST Doctoral Program
- _id: 0599E47C-7A3F-11EA-A408-12923DDC885E
  call_identifier: H2020
  grant_number: '863818'
  name: 'Formal Methods for Stochastic Models: Algorithms and Applications'
publication: International Conference on Computer Aided Verification
publication_identifier:
  eissn:
  - 1611-3349
  isbn:
  - '9783031377082'
  issn:
  - 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'MDPs as distribution transformers: Affine invariant synthesis for safety objectives'
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 13966
year: '2023'
...
---
_id: '14318'
abstract:
- lang: eng
  text: "Probabilistic recurrence relations (PRRs) are a standard formalism for describing
    the runtime of a randomized algorithm. Given a PRR and a time limit κ, we consider
    the tail probability Pr[T≥κ], i.e., the probability that the randomized runtime
    T of the PRR exceeds κ. Our focus is the formal analysis of tail bounds that aims
    at finding a tight asymptotic upper bound u≥Pr[T≥κ]. To address this problem,
    the classical and most well-known approach is the cookbook method by Karp (JACM
    1994), while other approaches are mostly limited to deriving tail bounds of specific
    PRRs via involved custom analysis.\r\nIn this work, we propose a novel approach
    for deriving the common exponentially-decreasing tail bounds for PRRs whose preprocessing
    time and random passed sizes observe discrete or (piecewise) uniform distribution
    and whose recursive call is either a single procedure call or a divide-and-conquer.
    We first establish a theoretical approach via Markov’s inequality, and then instantiate
    the theoretical approach with a template-based algorithmic approach via a refined
    treatment of exponentiation. Experimental evaluation shows that our algorithmic
    approach is capable of deriving tail bounds that are (i) asymptotically tighter
    than Karp’s method, (ii) match the best-known manually-derived asymptotic tail
    bound for QuickSelect, and (iii) is only slightly worse (with a loglogn factor)
    than the manually-proven optimal asymptotic tail bound for QuickSort. Moreover,
    our algorithmic approach handles all examples (including realistic PRRs such as
    QuickSort, QuickSelect, DiameterComputation, etc.) in less than 0.1 s, showing
    that our approach is efficient in practice."
acknowledgement: We thank Prof. Bican Xia for valuable information on the exponential
  theory of reals. The work is partially supported by the National Natural Science
  Foundation of China (NSFC) with Grant No. 62172271, ERC CoG 863818 (ForM-SMArt),
  the Hong Kong Research Grants Council ECS Project Number 26208122, the HKUST-Kaisa
  Joint Research Institute Project Grant HKJRI3A-055 and the HKUST Startup Grant R9272.
alternative_title:
- LNCS
article_processing_charge: Yes (in subscription journal)
author:
- first_name: Yican
  full_name: Sun, Yican
  last_name: Sun
- first_name: Hongfei
  full_name: Fu, Hongfei
  last_name: Fu
- first_name: Krishnendu
  full_name: Chatterjee, Krishnendu
  id: 2E5DCA20-F248-11E8-B48F-1D18A9856A87
  last_name: Chatterjee
  orcid: 0000-0002-4561-241X
- first_name: Amir Kafshdar
  full_name: Goharshady, Amir Kafshdar
  id: 391365CE-F248-11E8-B48F-1D18A9856A87
  last_name: Goharshady
  orcid: 0000-0003-1702-6584
citation:
  ama: 'Sun Y, Fu H, Chatterjee K, Goharshady AK. Automated tail bound analysis for probabilistic
    recurrence relations. In: <i>Computer Aided Verification</i>. Vol 13966. Springer
    Nature; 2023:16-39. doi:<a href="https://doi.org/10.1007/978-3-031-37709-9_2">10.1007/978-3-031-37709-9_2</a>'
  apa: 'Sun, Y., Fu, H., Chatterjee, K., &#38; Goharshady, A. K. (2023). Automated
    tail bound analysis for probabilistic recurrence relations. In <i>Computer Aided
    Verification</i> (Vol. 13966, pp. 16–39). Paris, France: Springer Nature. <a href="https://doi.org/10.1007/978-3-031-37709-9_2">https://doi.org/10.1007/978-3-031-37709-9_2</a>'
  chicago: Sun, Yican, Hongfei Fu, Krishnendu Chatterjee, and Amir Kafshdar Goharshady.
    “Automated Tail Bound Analysis for Probabilistic Recurrence Relations.” In <i>Computer
    Aided Verification</i>, 13966:16–39. Springer Nature, 2023. <a href="https://doi.org/10.1007/978-3-031-37709-9_2">https://doi.org/10.1007/978-3-031-37709-9_2</a>.
  ieee: Y. Sun, H. Fu, K. Chatterjee, and A. K. Goharshady, “Automated tail bound
    analysis for probabilistic recurrence relations,” in <i>Computer Aided Verification</i>,
    Paris, France, 2023, vol. 13966, pp. 16–39.
  ista: 'Sun Y, Fu H, Chatterjee K, Goharshady AK. 2023. Automated tail bound analysis
    for probabilistic recurrence relations. Computer Aided Verification. CAV: Computer
    Aided Verification, LNCS, vol. 13966, 16–39.'
  mla: Sun, Yican, et al. “Automated Tail Bound Analysis for Probabilistic Recurrence
    Relations.” <i>Computer Aided Verification</i>, vol. 13966, Springer Nature, 2023,
    pp. 16–39, doi:<a href="https://doi.org/10.1007/978-3-031-37709-9_2">10.1007/978-3-031-37709-9_2</a>.
  short: Y. Sun, H. Fu, K. Chatterjee, A.K. Goharshady, in:, Computer Aided Verification,
    Springer Nature, 2023, pp. 16–39.
conference:
  end_date: 2023-07-22
  location: Paris, France
  name: 'CAV: Computer Aided Verification'
  start_date: 2023-07-17
date_created: 2023-09-10T22:01:12Z
date_published: 2023-07-17T00:00:00Z
date_updated: 2025-07-14T09:09:57Z
day: '17'
ddc:
- '000'
department:
- _id: KrCh
doi: 10.1007/978-3-031-37709-9_2
ec_funded: 1
file:
- access_level: open_access
  checksum: 42917e086f8c7699f3bccf84f74fe000
  content_type: application/pdf
  creator: dernst
  date_created: 2023-09-20T08:24:47Z
  date_updated: 2023-09-20T08:24:47Z
  file_id: '14348'
  file_name: 2023_LNCS_Sun.pdf
  file_size: 624647
  relation: main_file
  success: 1
file_date_updated: 2023-09-20T08:24:47Z
has_accepted_license: '1'
intvolume: '     13966'
language:
- iso: eng
month: '07'
oa: 1
oa_version: Published Version
page: 16-39
project:
- _id: 0599E47C-7A3F-11EA-A408-12923DDC885E
  call_identifier: H2020
  grant_number: '863818'
  name: 'Formal Methods for Stochastic Models: Algorithms and Applications'
publication: Computer Aided Verification
publication_identifier:
  eissn:
  - 1611-3349
  isbn:
  - '9783031377082'
  issn:
  - 0302-9743
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
  link:
  - relation: software
    url: https://github.com/boyvolcano/PRR
scopus_import: '1'
status: public
title: Automated tail bound analysis for probabilistic recurrence relations
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 13966
year: '2023'
...
---
_id: '14319'
abstract:
- lang: eng
  text: "We study multigraphs whose edge-sets are the union of three perfect matchings,
    M1, M2, and M3. Given such a graph G and any a1; a2; a3 2 N with a1 +a2 +a3 6
    n - 2, we show there exists a matching M of G with jM \\ Mij = ai for each i 2
    f1; 2; 3g. The bound n - 2 in the theorem is best possible in general. We conjecture
    however that if G is bipartite, the same result holds with n - 2 replaced by n
    - 1. We give a construction that shows such a result would be tight. We\r\nalso
    make a conjecture generalising the Ryser-Brualdi-Stein conjecture with colour\r\nmultiplicities."
acknowledgement: Anastos has received funding from the European Union’s Horizon 2020
  research and in-novation programme under the Marie Sk lodowska-Curie grant agreement
  No 101034413.Fabian’s research is supported by the Deutsche Forschungsgemeinschaft
  (DFG, GermanResearch Foundation) Graduiertenkolleg “Facets of Complexity” (GRK 2434).
article_number: P3.10
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: Michael
  full_name: Anastos, Michael
  id: 0b2a4358-bb35-11ec-b7b9-e3279b593dbb
  last_name: Anastos
- first_name: David
  full_name: Fabian, David
  last_name: Fabian
- first_name: Alp
  full_name: Müyesser, Alp
  last_name: Müyesser
- first_name: Tibor
  full_name: Szabó, Tibor
  last_name: Szabó
citation:
  ama: Anastos M, Fabian D, Müyesser A, Szabó T. Splitting matchings and the Ryser-Brualdi-Stein
    conjecture for multisets. <i>Electronic Journal of Combinatorics</i>. 2023;30(3).
    doi:<a href="https://doi.org/10.37236/11714">10.37236/11714</a>
  apa: Anastos, M., Fabian, D., Müyesser, A., &#38; Szabó, T. (2023). Splitting matchings
    and the Ryser-Brualdi-Stein conjecture for multisets. <i>Electronic Journal of
    Combinatorics</i>. Electronic Journal of Combinatorics. <a href="https://doi.org/10.37236/11714">https://doi.org/10.37236/11714</a>
  chicago: Anastos, Michael, David Fabian, Alp Müyesser, and Tibor Szabó. “Splitting
    Matchings and the Ryser-Brualdi-Stein Conjecture for Multisets.” <i>Electronic
    Journal of Combinatorics</i>. Electronic Journal of Combinatorics, 2023. <a href="https://doi.org/10.37236/11714">https://doi.org/10.37236/11714</a>.
  ieee: M. Anastos, D. Fabian, A. Müyesser, and T. Szabó, “Splitting matchings and
    the Ryser-Brualdi-Stein conjecture for multisets,” <i>Electronic Journal of Combinatorics</i>,
    vol. 30, no. 3. Electronic Journal of Combinatorics, 2023.
  ista: Anastos M, Fabian D, Müyesser A, Szabó T. 2023. Splitting matchings and the
    Ryser-Brualdi-Stein conjecture for multisets. Electronic Journal of Combinatorics.
    30(3), P3.10.
  mla: Anastos, Michael, et al. “Splitting Matchings and the Ryser-Brualdi-Stein Conjecture
    for Multisets.” <i>Electronic Journal of Combinatorics</i>, vol. 30, no. 3, P3.10,
    Electronic Journal of Combinatorics, 2023, doi:<a href="https://doi.org/10.37236/11714">10.37236/11714</a>.
  short: M. Anastos, D. Fabian, A. Müyesser, T. Szabó, Electronic Journal of Combinatorics
    30 (2023).
date_created: 2023-09-10T22:01:12Z
date_published: 2023-07-28T00:00:00Z
date_updated: 2023-09-15T08:12:30Z
day: '28'
ddc:
- '510'
department:
- _id: MaKw
doi: 10.37236/11714
ec_funded: 1
external_id:
  arxiv:
  - '2212.03100'
file:
- access_level: open_access
  checksum: 52c46c8cb329f9aaee9ade01525f317b
  content_type: application/pdf
  creator: dernst
  date_created: 2023-09-15T08:02:09Z
  date_updated: 2023-09-15T08:02:09Z
  file_id: '14338'
  file_name: 2023_elecJournCombinatorics_Anastos.pdf
  file_size: 247917
  relation: main_file
  success: 1
file_date_updated: 2023-09-15T08:02:09Z
has_accepted_license: '1'
intvolume: '        30'
issue: '3'
language:
- iso: eng
license: https://creativecommons.org/licenses/by-nd/4.0/
month: '07'
oa: 1
oa_version: Published Version
project:
- _id: fc2ed2f7-9c52-11eb-aca3-c01059dda49c
  call_identifier: H2020
  grant_number: '101034413'
  name: 'IST-BRIDGE: International postdoctoral program'
publication: Electronic Journal of Combinatorics
publication_identifier:
  eissn:
  - 1077-8926
publication_status: published
publisher: Electronic Journal of Combinatorics
quality_controlled: '1'
scopus_import: '1'
status: public
title: Splitting matchings and the Ryser-Brualdi-Stein conjecture for multisets
tmp:
  image: /image/cc_by_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nd/4.0/legalcode
  name: Creative Commons Attribution-NoDerivatives 4.0 International (CC BY-ND 4.0)
  short: CC BY-ND (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 30
year: '2023'
...
---
_id: '14320'
abstract:
- lang: eng
  text: The development of two-dimensional materials has resulted in a diverse range
    of novel, high-quality compounds with increasing complexity. A key requirement
    for a comprehensive quantitative theory is the accurate determination of these
    materials' band structure parameters. However, this task is challenging due to
    the intricate band structures and the indirect nature of experimental probes.
    In this work, we introduce a general framework to derive band structure parameters
    from experimental data using deep neural networks. We applied our method to the
    penetration field capacitance measurement of trilayer graphene, an effective probe
    of its density of states. First, we demonstrate that a trained deep network gives
    accurate predictions for the penetration field capacitance as a function of tight-binding
    parameters. Next, we use the fast and accurate predictions from the trained network
    to automatically determine tight-binding parameters directly from experimental
    data, with extracted parameters being in a good agreement with values in the literature.
    We conclude by discussing potential applications of our method to other materials
    and experimental techniques beyond penetration field capacitance.
acknowledgement: A.F.Y. acknowledges primary support from the Department of Energy
  under award DE-SC0020043, and additional support from the Gordon and Betty Moore
  Foundation under award GBMF9471 for group operations.
article_number: '125411'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Paul M
  full_name: Henderson, Paul M
  id: 13C09E74-18D9-11E9-8878-32CFE5697425
  last_name: Henderson
  orcid: 0000-0002-5198-7445
- first_name: Areg
  full_name: Ghazaryan, Areg
  id: 4AF46FD6-F248-11E8-B48F-1D18A9856A87
  last_name: Ghazaryan
  orcid: 0000-0001-9666-3543
- first_name: Alexander A.
  full_name: Zibrov, Alexander A.
  last_name: Zibrov
- first_name: Andrea F.
  full_name: Young, Andrea F.
  last_name: Young
- first_name: Maksym
  full_name: Serbyn, Maksym
  id: 47809E7E-F248-11E8-B48F-1D18A9856A87
  last_name: Serbyn
  orcid: 0000-0002-2399-5827
citation:
  ama: 'Henderson PM, Ghazaryan A, Zibrov AA, Young AF, Serbyn M. Deep learning extraction
    of band structure parameters from density of states: A case study on trilayer
    graphene. <i>Physical Review B</i>. 2023;108(12). doi:<a href="https://doi.org/10.1103/physrevb.108.125411">10.1103/physrevb.108.125411</a>'
  apa: 'Henderson, P. M., Ghazaryan, A., Zibrov, A. A., Young, A. F., &#38; Serbyn,
    M. (2023). Deep learning extraction of band structure parameters from density
    of states: A case study on trilayer graphene. <i>Physical Review B</i>. American
    Physical Society. <a href="https://doi.org/10.1103/physrevb.108.125411">https://doi.org/10.1103/physrevb.108.125411</a>'
  chicago: 'Henderson, Paul M, Areg Ghazaryan, Alexander A. Zibrov, Andrea F. Young,
    and Maksym Serbyn. “Deep Learning Extraction of Band Structure Parameters from
    Density of States: A Case Study on Trilayer Graphene.” <i>Physical Review B</i>.
    American Physical Society, 2023. <a href="https://doi.org/10.1103/physrevb.108.125411">https://doi.org/10.1103/physrevb.108.125411</a>.'
  ieee: 'P. M. Henderson, A. Ghazaryan, A. A. Zibrov, A. F. Young, and M. Serbyn,
    “Deep learning extraction of band structure parameters from density of states:
    A case study on trilayer graphene,” <i>Physical Review B</i>, vol. 108, no. 12.
    American Physical Society, 2023.'
  ista: 'Henderson PM, Ghazaryan A, Zibrov AA, Young AF, Serbyn M. 2023. Deep learning
    extraction of band structure parameters from density of states: A case study on
    trilayer graphene. Physical Review B. 108(12), 125411.'
  mla: 'Henderson, Paul M., et al. “Deep Learning Extraction of Band Structure Parameters
    from Density of States: A Case Study on Trilayer Graphene.” <i>Physical Review
    B</i>, vol. 108, no. 12, 125411, American Physical Society, 2023, doi:<a href="https://doi.org/10.1103/physrevb.108.125411">10.1103/physrevb.108.125411</a>.'
  short: P.M. Henderson, A. Ghazaryan, A.A. Zibrov, A.F. Young, M. Serbyn, Physical
    Review B 108 (2023).
date_created: 2023-09-12T07:12:12Z
date_published: 2023-09-15T00:00:00Z
date_updated: 2023-09-20T09:38:24Z
day: '15'
department:
- _id: MaSe
- _id: ChLa
- _id: MiLe
doi: 10.1103/physrevb.108.125411
external_id:
  arxiv:
  - '2210.06310'
intvolume: '       108'
issue: '12'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2210.06310
month: '09'
oa: 1
oa_version: Preprint
publication: Physical Review B
publication_identifier:
  eissn:
  - 2469-9969
  issn:
  - 2469-9950
publication_status: published
publisher: American Physical Society
quality_controlled: '1'
scopus_import: '1'
status: public
title: 'Deep learning extraction of band structure parameters from density of states:
  A case study on trilayer graphene'
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 108
year: '2023'
...
---
_id: '14321'
abstract:
- lang: eng
  text: We demonstrate the possibility of a coupling between the magnetization direction
    of a ferromagnet and the tilting angle of adsorbed achiral molecules. To illustrate
    the mechanism of the coupling, we analyze a minimal Stoner model that includes
    Rashba spin–orbit coupling due to the electric field on the surface of the ferromagnet.
    The proposed mechanism allows us to study magnetic anisotropy of the system with
    an extended Stoner–Wohlfarth model and argue that adsorbed achiral molecules can
    change magnetocrystalline anisotropy of the substrate. Our research aims to motivate
    further experimental studies of the current-free chirality induced spin selectivity
    effect involving both enantiomers.
acknowledgement: "We thank Zhanybek Alpichshev, Mohammad Reza Safari, Binghai Yan,
  and Yossi Paltiel for enlightening discussions.\r\nM.L. acknowledges support from
  the European Research Council (ERC) Starting Grant No. 801770 (ANGULON). A. C. received
  funding from the European Union’s Horizon Europe research and innovation program
  under the Marie Skłodowska-Curie Grant Agreement No. 101062862 - NeqMolRot."
article_number: '104103'
article_processing_charge: Yes (in subscription journal)
article_type: original
arxiv: 1
author:
- first_name: Ragheed
  full_name: Al Hyder, Ragheed
  id: d1c405be-ae15-11ed-8510-ccf53278162e
  last_name: Al Hyder
- first_name: Alberto
  full_name: Cappellaro, Alberto
  id: 9d13b3cb-30a2-11eb-80dc-f772505e8660
  last_name: Cappellaro
  orcid: 0000-0001-6110-2359
- first_name: Mikhail
  full_name: Lemeshko, Mikhail
  id: 37CB05FA-F248-11E8-B48F-1D18A9856A87
  last_name: Lemeshko
  orcid: 0000-0002-6990-7802
- first_name: Artem
  full_name: Volosniev, Artem
  id: 37D278BC-F248-11E8-B48F-1D18A9856A87
  last_name: Volosniev
  orcid: 0000-0003-0393-5525
citation:
  ama: Al Hyder R, Cappellaro A, Lemeshko M, Volosniev A. Achiral dipoles on a ferromagnet
    can affect its magnetization direction. <i>The Journal of Chemical Physics</i>.
    2023;159(10). doi:<a href="https://doi.org/10.1063/5.0165806">10.1063/5.0165806</a>
  apa: Al Hyder, R., Cappellaro, A., Lemeshko, M., &#38; Volosniev, A. (2023). Achiral
    dipoles on a ferromagnet can affect its magnetization direction. <i>The Journal
    of Chemical Physics</i>. AIP Publishing. <a href="https://doi.org/10.1063/5.0165806">https://doi.org/10.1063/5.0165806</a>
  chicago: Al Hyder, Ragheed, Alberto Cappellaro, Mikhail Lemeshko, and Artem Volosniev.
    “Achiral Dipoles on a Ferromagnet Can Affect Its Magnetization Direction.” <i>The
    Journal of Chemical Physics</i>. AIP Publishing, 2023. <a href="https://doi.org/10.1063/5.0165806">https://doi.org/10.1063/5.0165806</a>.
  ieee: R. Al Hyder, A. Cappellaro, M. Lemeshko, and A. Volosniev, “Achiral dipoles
    on a ferromagnet can affect its magnetization direction,” <i>The Journal of Chemical
    Physics</i>, vol. 159, no. 10. AIP Publishing, 2023.
  ista: Al Hyder R, Cappellaro A, Lemeshko M, Volosniev A. 2023. Achiral dipoles on
    a ferromagnet can affect its magnetization direction. The Journal of Chemical
    Physics. 159(10), 104103.
  mla: Al Hyder, Ragheed, et al. “Achiral Dipoles on a Ferromagnet Can Affect Its
    Magnetization Direction.” <i>The Journal of Chemical Physics</i>, vol. 159, no.
    10, 104103, AIP Publishing, 2023, doi:<a href="https://doi.org/10.1063/5.0165806">10.1063/5.0165806</a>.
  short: R. Al Hyder, A. Cappellaro, M. Lemeshko, A. Volosniev, The Journal of Chemical
    Physics 159 (2023).
date_created: 2023-09-13T09:25:09Z
date_published: 2023-09-11T00:00:00Z
date_updated: 2023-09-20T09:48:12Z
day: '11'
ddc:
- '530'
department:
- _id: MiLe
doi: 10.1063/5.0165806
ec_funded: 1
external_id:
  arxiv:
  - '2306.17592'
  pmid:
  - '37694742'
file:
- access_level: open_access
  checksum: 507ab65ab29e2c987c94cabad7c5370b
  content_type: application/pdf
  creator: acappell
  date_created: 2023-09-13T09:34:20Z
  date_updated: 2023-09-13T09:34:20Z
  file_id: '14322'
  file_name: 104103_1_5.0165806.pdf
  file_size: 5749653
  relation: main_file
  success: 1
file_date_updated: 2023-09-13T09:34:20Z
has_accepted_license: '1'
intvolume: '       159'
issue: '10'
keyword:
- Physical and Theoretical Chemistry
- General Physics and Astronomy
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: bd7b5202-d553-11ed-ba76-9b1c1b258338
  grant_number: '101062862'
  name: Non-equilibrium Field Theory of Molecular Rotations
- _id: 2688CF98-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '801770'
  name: 'Angulon: physics and applications of a new quasiparticle'
publication: The Journal of Chemical Physics
publication_identifier:
  eissn:
  - 1089-7690
  issn:
  - 0021-9606
publication_status: published
publisher: AIP Publishing
quality_controlled: '1'
scopus_import: '1'
status: public
title: Achiral dipoles on a ferromagnet can affect its magnetization direction
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 159
year: '2023'
...
---
_id: '14323'
abstract:
- lang: eng
  text: Morphogens are signaling molecules that are known for their prominent role
    in pattern formation within developing tissues. In addition to patterning, morphogens
    also control tissue growth. However, the underlying mechanisms are poorly understood.
    We studied the role of morphogens in regulating tissue growth in the developing
    vertebrate neural tube. In this system, opposing morphogen gradients of Shh and
    BMP establish the dorsoventral pattern of neural progenitor domains. Perturbations
    in these morphogen pathways result in alterations in tissue growth and cell cycle
    progression, however, it has been unclear what cellular process is affected. To
    address this, we analysed the rates of cell proliferation and cell death in mouse
    mutants in which signaling is perturbed, as well as in chick neural plate explants
    exposed to defined concentrations of signaling activators or inhibitors. Our results
    indicated that the rate of cell proliferation was not altered in these assays.
    By contrast, both the Shh and BMP signaling pathways had profound effects on neural
    progenitor survival. Our results indicate that these pathways synergise to promote
    cell survival within neural progenitors. Consistent with this, we found that progenitors
    within the intermediate region of the neural tube, where the combined levels of
    Shh and BMP are the lowest, are most prone to cell death when signaling activity
    is inhibited. In addition, we found that downregulation of Shh results in increased
    apoptosis within the roof plate, which is the dorsal source of BMP ligand production.
    This revealed a cross-interaction between the Shh and BMP morphogen signaling
    pathways that may be relevant for understanding how gradients scale in neural
    tubes with different overall sizes. We further studied the mechanism acting downstream
    of Shh in cell survival regulation using genetic and genomic approaches. We propose
    that Shh transcriptionally regulates a non-canonical apoptotic pathway. Altogether,
    our study points to a novel role of opposing morphogen gradients in tissue size
    regulation and provides new insights into complex interactions between Shh and
    BMP signaling gradients in the neural tube.
acknowledged_ssus:
- _id: Bio
- _id: PreCl
alternative_title:
- ISTA Thesis
article_processing_charge: No
author:
- first_name: Katarzyna
  full_name: Kuzmicz-Kowalska, Katarzyna
  id: 4CED352A-F248-11E8-B48F-1D18A9856A87
  last_name: Kuzmicz-Kowalska
citation:
  ama: Kuzmicz-Kowalska K. Regulation of neural progenitor survival by Shh and BMP
    in the developing spinal cord. 2023. doi:<a href="https://doi.org/10.15479/at:ista:14323">10.15479/at:ista:14323</a>
  apa: Kuzmicz-Kowalska, K. (2023). <i>Regulation of neural progenitor survival by
    Shh and BMP in the developing spinal cord</i>. Institute of Science and Technology
    Austria. <a href="https://doi.org/10.15479/at:ista:14323">https://doi.org/10.15479/at:ista:14323</a>
  chicago: Kuzmicz-Kowalska, Katarzyna. “Regulation of Neural Progenitor Survival
    by Shh and BMP in the Developing Spinal Cord.” Institute of Science and Technology
    Austria, 2023. <a href="https://doi.org/10.15479/at:ista:14323">https://doi.org/10.15479/at:ista:14323</a>.
  ieee: K. Kuzmicz-Kowalska, “Regulation of neural progenitor survival by Shh and
    BMP in the developing spinal cord,” Institute of Science and Technology Austria,
    2023.
  ista: Kuzmicz-Kowalska K. 2023. Regulation of neural progenitor survival by Shh
    and BMP in the developing spinal cord. Institute of Science and Technology Austria.
  mla: Kuzmicz-Kowalska, Katarzyna. <i>Regulation of Neural Progenitor Survival by
    Shh and BMP in the Developing Spinal Cord</i>. Institute of Science and Technology
    Austria, 2023, doi:<a href="https://doi.org/10.15479/at:ista:14323">10.15479/at:ista:14323</a>.
  short: K. Kuzmicz-Kowalska, Regulation of Neural Progenitor Survival by Shh and
    BMP in the Developing Spinal Cord, Institute of Science and Technology Austria,
    2023.
date_created: 2023-09-13T10:07:18Z
date_published: 2023-09-13T00:00:00Z
date_updated: 2024-03-07T15:02:59Z
day: '13'
ddc:
- '570'
degree_awarded: PhD
department:
- _id: GradSch
- _id: AnKi
doi: 10.15479/at:ista:14323
file:
- access_level: closed
  checksum: bd83596869c814b24aeff7077d031c0e
  content_type: application/pdf
  creator: kkuzmicz
  date_created: 2023-09-13T09:52:52Z
  date_updated: 2023-09-13T10:08:25Z
  embargo: 2025-03-13
  embargo_to: open_access
  file_id: '14324'
  file_name: PhDThesis_KK_final_pdfA.pdf
  file_size: 10147911
  relation: main_file
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  checksum: aa2757ae4c3478041fd7e62c587d3e4d
  content_type: application/vnd.openxmlformats-officedocument.wordprocessingml.document
  creator: kkuzmicz
  date_created: 2023-09-13T09:53:29Z
  date_updated: 2023-09-13T09:53:29Z
  file_id: '14325'
  file_name: thesis_KK_final_corrections_092023.docx
  file_size: 103980668
  relation: source_file
file_date_updated: 2023-09-13T10:08:25Z
has_accepted_license: '1'
language:
- iso: eng
month: '09'
oa_version: Published Version
page: '151'
project:
- _id: 267AF0E4-B435-11E9-9278-68D0E5697425
  name: The role of morphogens in the regulation of neural tube growth
publication_identifier:
  issn:
  - 2663 - 337X
publication_status: published
publisher: Institute of Science and Technology Austria
related_material:
  record:
  - id: '7883'
    relation: part_of_dissertation
    status: public
status: public
supervisor:
- first_name: Anna
  full_name: Kicheva, Anna
  id: 3959A2A0-F248-11E8-B48F-1D18A9856A87
  last_name: Kicheva
  orcid: 0000-0003-4509-4998
title: Regulation of neural progenitor survival by Shh and BMP in the developing spinal
  cord
tmp:
  image: /images/cc_by_nc_nd.png
  legal_code_url: https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode
  name: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
    (CC BY-NC-ND 4.0)
  short: CC BY-NC-ND (4.0)
type: dissertation
user_id: 8b945eb4-e2f2-11eb-945a-df72226e66a9
year: '2023'
...
---
_id: '14333'
abstract:
- lang: eng
  text: "As causal ground truth is incredibly rare, causal discovery algorithms are\r\ncommonly
    only evaluated on simulated data. This is concerning, given that\r\nsimulations
    reflect common preconceptions about generating processes regarding\r\nnoise distributions,
    model classes, and more. In this work, we propose a novel\r\nmethod for falsifying
    the output of a causal discovery algorithm in the absence\r\nof ground truth.
    Our key insight is that while statistical learning seeks\r\nstability across subsets
    of data points, causal learning should seek stability\r\nacross subsets of variables.
    Motivated by this insight, our method relies on a\r\nnotion of compatibility between
    causal graphs learned on different subsets of\r\nvariables. We prove that detecting
    incompatibilities can falsify wrongly\r\ninferred causal relations due to violation
    of assumptions or errors from finite\r\nsample effects. Although passing such
    compatibility tests is only a necessary\r\ncriterion for good performance, we
    argue that it provides strong evidence for\r\nthe causal models whenever compatibility
    entails strong implications for the\r\njoint distribution. We also demonstrate
    experimentally that detection of\r\nincompatibilities can aid in causal model
    selection."
article_number: '2307.09552'
article_processing_charge: No
arxiv: 1
author:
- first_name: Philipp M.
  full_name: Faller, Philipp M.
  last_name: Faller
- first_name: Leena Chennuru
  full_name: Vankadara, Leena Chennuru
  last_name: Vankadara
- first_name: Atalanti A.
  full_name: Mastakouri, Atalanti A.
  last_name: Mastakouri
- first_name: Francesco
  full_name: Locatello, Francesco
  id: 26cfd52f-2483-11ee-8040-88983bcc06d4
  last_name: Locatello
  orcid: 0000-0002-4850-0683
- first_name: Dominik
  full_name: Janzing, Dominik
  last_name: Janzing
citation:
  ama: 'Faller PM, Vankadara LC, Mastakouri AA, Locatello F, Janzing D. Self-compatibility:
    Evaluating causal discovery without ground truth. <i>arXiv</i>. doi:<a href="https://doi.org/10.48550/arXiv.2307.09552">10.48550/arXiv.2307.09552</a>'
  apa: 'Faller, P. M., Vankadara, L. C., Mastakouri, A. A., Locatello, F., &#38; Janzing,
    D. (n.d.). Self-compatibility: Evaluating causal discovery without ground truth.
    <i>arXiv</i>. <a href="https://doi.org/10.48550/arXiv.2307.09552">https://doi.org/10.48550/arXiv.2307.09552</a>'
  chicago: 'Faller, Philipp M., Leena Chennuru Vankadara, Atalanti A. Mastakouri,
    Francesco Locatello, and Dominik Janzing. “Self-Compatibility: Evaluating Causal
    Discovery without Ground Truth.” <i>ArXiv</i>, n.d. <a href="https://doi.org/10.48550/arXiv.2307.09552">https://doi.org/10.48550/arXiv.2307.09552</a>.'
  ieee: 'P. M. Faller, L. C. Vankadara, A. A. Mastakouri, F. Locatello, and D. Janzing,
    “Self-compatibility: Evaluating causal discovery without ground truth,” <i>arXiv</i>.
    .'
  ista: 'Faller PM, Vankadara LC, Mastakouri AA, Locatello F, Janzing D. Self-compatibility:
    Evaluating causal discovery without ground truth. arXiv, 2307.09552.'
  mla: 'Faller, Philipp M., et al. “Self-Compatibility: Evaluating Causal Discovery
    without Ground Truth.” <i>ArXiv</i>, 2307.09552, doi:<a href="https://doi.org/10.48550/arXiv.2307.09552">10.48550/arXiv.2307.09552</a>.'
  short: P.M. Faller, L.C. Vankadara, A.A. Mastakouri, F. Locatello, D. Janzing, ArXiv
    (n.d.).
date_created: 2023-09-13T12:44:59Z
date_published: 2023-07-18T00:00:00Z
date_updated: 2023-09-13T12:47:53Z
day: '18'
department:
- _id: FrLo
doi: 10.48550/arXiv.2307.09552
extern: '1'
external_id:
  arxiv:
  - '2307.09552'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2307.09552
month: '07'
oa: 1
oa_version: Preprint
publication: arXiv
publication_status: submitted
status: public
title: 'Self-compatibility: Evaluating causal discovery without ground truth'
type: preprint
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2023'
...
---
_id: '14334'
abstract:
- lang: eng
  text: Quantum kinetically constrained models have recently attracted significant
    attention due to their anomalous dynamics and thermalization. In this work, we
    introduce a hitherto unexplored family of kinetically constrained models featuring
    conserved particle number and strong inversion-symmetry breaking due to facilitated
    hopping. We demonstrate that these models provide a generic example of so-called
    quantum Hilbert space fragmentation, that is manifested in disconnected sectors
    in the Hilbert space that are not apparent in the computational basis. Quantum
    Hilbert space fragmentation leads to an exponential in system size number of eigenstates
    with exactly zero entanglement entropy across several bipartite cuts. These eigenstates
    can be probed dynamically using quenches from simple initial product states. In
    addition, we study the particle spreading under unitary dynamics launched from
    the domain wall state, and find faster than diffusive dynamics at high particle
    densities, that crosses over into logarithmically slow relaxation at smaller densities.
    Using a classically simulable cellular automaton, we reproduce the logarithmic
    dynamics observed in the quantum case. Our work suggests that particle conserving
    constrained models with inversion symmetry breaking realize so far unexplored
    dynamical behavior and invite their further theoretical and experimental studies.
acknowledgement: "We would like to thank Raimel A. Medina, Hansveer Singh, and Dmitry
  Abanin for useful\r\ndiscussions.The authors acknowledge support by the European
  Research Council\r\n(ERC) under the European Union’s Horizon 2020 research and innovation
  program (Grant\r\nAgreement No. 850899). We acknowledge support by the Erwin Schrödinger
  International\r\nInstitute for Mathematics and Physics (ESI)."
article_number: '093'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Pietro
  full_name: Brighi, Pietro
  id: 4115AF5C-F248-11E8-B48F-1D18A9856A87
  last_name: Brighi
  orcid: 0000-0002-7969-2729
- first_name: Marko
  full_name: Ljubotina, Marko
  id: F75EE9BE-5C90-11EA-905D-16643DDC885E
  last_name: Ljubotina
  orcid: 0000-0003-0038-7068
- first_name: Maksym
  full_name: Serbyn, Maksym
  id: 47809E7E-F248-11E8-B48F-1D18A9856A87
  last_name: Serbyn
  orcid: 0000-0002-2399-5827
citation:
  ama: Brighi P, Ljubotina M, Serbyn M. Hilbert space fragmentation and slow dynamics
    in particle-conserving quantum East models. <i>SciPost Physics</i>. 2023;15(3).
    doi:<a href="https://doi.org/10.21468/scipostphys.15.3.093">10.21468/scipostphys.15.3.093</a>
  apa: Brighi, P., Ljubotina, M., &#38; Serbyn, M. (2023). Hilbert space fragmentation
    and slow dynamics in particle-conserving quantum East models. <i>SciPost Physics</i>.
    SciPost Foundation. <a href="https://doi.org/10.21468/scipostphys.15.3.093">https://doi.org/10.21468/scipostphys.15.3.093</a>
  chicago: Brighi, Pietro, Marko Ljubotina, and Maksym Serbyn. “Hilbert Space Fragmentation
    and Slow Dynamics in Particle-Conserving Quantum East Models.” <i>SciPost Physics</i>.
    SciPost Foundation, 2023. <a href="https://doi.org/10.21468/scipostphys.15.3.093">https://doi.org/10.21468/scipostphys.15.3.093</a>.
  ieee: P. Brighi, M. Ljubotina, and M. Serbyn, “Hilbert space fragmentation and slow
    dynamics in particle-conserving quantum East models,” <i>SciPost Physics</i>,
    vol. 15, no. 3. SciPost Foundation, 2023.
  ista: Brighi P, Ljubotina M, Serbyn M. 2023. Hilbert space fragmentation and slow
    dynamics in particle-conserving quantum East models. SciPost Physics. 15(3), 093.
  mla: Brighi, Pietro, et al. “Hilbert Space Fragmentation and Slow Dynamics in Particle-Conserving
    Quantum East Models.” <i>SciPost Physics</i>, vol. 15, no. 3, 093, SciPost Foundation,
    2023, doi:<a href="https://doi.org/10.21468/scipostphys.15.3.093">10.21468/scipostphys.15.3.093</a>.
  short: P. Brighi, M. Ljubotina, M. Serbyn, SciPost Physics 15 (2023).
date_created: 2023-09-14T13:08:23Z
date_published: 2023-09-13T00:00:00Z
date_updated: 2023-09-20T10:46:29Z
day: '13'
ddc:
- '530'
department:
- _id: MaSe
doi: 10.21468/scipostphys.15.3.093
ec_funded: 1
external_id:
  arxiv:
  - '2210.15607'
file:
- access_level: open_access
  checksum: 4cef6a8021f6b6c47ab2f2f2b1387ac2
  content_type: application/pdf
  creator: dernst
  date_created: 2023-09-20T10:46:10Z
  date_updated: 2023-09-20T10:46:10Z
  file_id: '14350'
  file_name: 2023_SciPostPhysics_Brighi.pdf
  file_size: 4866506
  relation: main_file
  success: 1
file_date_updated: 2023-09-20T10:46:10Z
has_accepted_license: '1'
intvolume: '        15'
issue: '3'
keyword:
- General Physics and Astronomy
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
project:
- _id: 23841C26-32DE-11EA-91FC-C7463DDC885E
  call_identifier: H2020
  grant_number: '850899'
  name: 'Non-Ergodic Quantum Matter: Universality, Dynamics and Control'
publication: SciPost Physics
publication_identifier:
  issn:
  - 2542-4653
publication_status: published
publisher: SciPost Foundation
quality_controlled: '1'
related_material:
  record:
  - id: '12750'
    relation: earlier_version
    status: public
status: public
title: Hilbert space fragmentation and slow dynamics in particle-conserving quantum
  East models
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 15
year: '2023'
...
---
_id: '14339'
abstract:
- lang: eng
  text: Lateral roots are typically maintained at non-vertical angles with respect
    to gravity. These gravitropic setpoint angles are intriguing because their maintenance
    requires that roots are able to effect growth response both with and against the
    gravity vector, a phenomenon previously attributed to gravitropism acting against
    an antigravitropic offset mechanism. Here we show how the components mediating
    gravitropism in the vertical primary root—PINs and phosphatases acting upon them—are
    reconfigured in their regulation such that lateral root growth at a range of angles
    can be maintained. We show that the ability of Arabidopsis lateral roots to bend
    both downward and upward requires the generation of auxin asymmetries and is driven
    by angle-dependent variation in downward gravitropic auxin flux acting against
    angle-independent upward, antigravitropic flux. Further, we demonstrate a symmetry
    in auxin distribution in lateral roots at gravitropic setpoint angle that can
    be traced back to a net, balanced polarization of PIN3 and PIN7 auxin transporters
    in the columella. These auxin fluxes are shifted by altering PIN protein phosphoregulation
    in the columella, either by introducing PIN3 phosphovariant versions or via manipulation
    of levels of the phosphatase subunit PP2A/RCN1. Finally, we show that auxin, in
    addition to driving lateral root directional growth, acts within the lateral root
    columella to induce more vertical growth by increasing RCN1 levels, causing a
    downward shift in PIN3 localization, thereby diminishing the magnitude of the
    upward, antigravitropic auxin flux.
acknowledgement: We thank D. Weijers, C. Schwechheimer and R. Offringa for generous
  sharing of published and unpublished materials and P. Masson for advice on the use
  of the ARL2 promoter. We are grateful to M. Del Bianco and O. Leyser for critical
  reading of the manuscript. This work was supported by the BBSRC (grants BB/N010124/1
  and BB/R000859/1 to S.K.), the Gatsby Charitable Foundation and the Leverhulme Trust
  (RPG-2018-137 to S.K.).
article_processing_charge: Yes (in subscription journal)
article_type: original
author:
- first_name: S
  full_name: Roychoudhry, S
  last_name: Roychoudhry
- first_name: K
  full_name: Sageman-Furnas, K
  last_name: Sageman-Furnas
- first_name: C
  full_name: Wolverton, C
  last_name: Wolverton
- first_name: Peter
  full_name: Grones, Peter
  id: 399876EC-F248-11E8-B48F-1D18A9856A87
  last_name: Grones
- first_name: Shutang
  full_name: Tan, Shutang
  id: 2DE75584-F248-11E8-B48F-1D18A9856A87
  last_name: Tan
  orcid: 0000-0002-0471-8285
- first_name: Gergely
  full_name: Molnar, Gergely
  id: 34F1AF46-F248-11E8-B48F-1D18A9856A87
  last_name: Molnar
- first_name: M
  full_name: De Angelis, M
  last_name: De Angelis
- first_name: HL
  full_name: Goodman, HL
  last_name: Goodman
- first_name: N
  full_name: Capstaff, N
  last_name: Capstaff
- first_name: Lloyd
  full_name: JPB, Lloyd
  last_name: JPB
- first_name: J
  full_name: Mullen, J
  last_name: Mullen
- first_name: R
  full_name: Hangarter, R
  last_name: Hangarter
- first_name: Jiří
  full_name: Friml, Jiří
  id: 4159519E-F248-11E8-B48F-1D18A9856A87
  last_name: Friml
  orcid: 0000-0002-8302-7596
- first_name: S
  full_name: Kepinski, S
  last_name: Kepinski
citation:
  ama: Roychoudhry S, Sageman-Furnas K, Wolverton C, et al. Antigravitropic PIN polarization
    maintains non-vertical growth in lateral roots. <i>Nature Plants</i>. 2023;9:1500-1513.
    doi:<a href="https://doi.org/10.1038/s41477-023-01478-x">10.1038/s41477-023-01478-x</a>
  apa: Roychoudhry, S., Sageman-Furnas, K., Wolverton, C., Grones, P., Tan, S., Molnar,
    G., … Kepinski, S. (2023). Antigravitropic PIN polarization maintains non-vertical
    growth in lateral roots. <i>Nature Plants</i>. Springer Nature. <a href="https://doi.org/10.1038/s41477-023-01478-x">https://doi.org/10.1038/s41477-023-01478-x</a>
  chicago: Roychoudhry, S, K Sageman-Furnas, C Wolverton, Peter Grones, Shutang Tan,
    Gergely Molnar, M De Angelis, et al. “Antigravitropic PIN Polarization Maintains
    Non-Vertical Growth in Lateral Roots.” <i>Nature Plants</i>. Springer Nature,
    2023. <a href="https://doi.org/10.1038/s41477-023-01478-x">https://doi.org/10.1038/s41477-023-01478-x</a>.
  ieee: S. Roychoudhry <i>et al.</i>, “Antigravitropic PIN polarization maintains
    non-vertical growth in lateral roots,” <i>Nature Plants</i>, vol. 9. Springer
    Nature, pp. 1500–1513, 2023.
  ista: Roychoudhry S, Sageman-Furnas K, Wolverton C, Grones P, Tan S, Molnar G, De
    Angelis M, Goodman H, Capstaff N, JPB L, Mullen J, Hangarter R, Friml J, Kepinski
    S. 2023. Antigravitropic PIN polarization maintains non-vertical growth in lateral
    roots. Nature Plants. 9, 1500–1513.
  mla: Roychoudhry, S., et al. “Antigravitropic PIN Polarization Maintains Non-Vertical
    Growth in Lateral Roots.” <i>Nature Plants</i>, vol. 9, Springer Nature, 2023,
    pp. 1500–13, doi:<a href="https://doi.org/10.1038/s41477-023-01478-x">10.1038/s41477-023-01478-x</a>.
  short: S. Roychoudhry, K. Sageman-Furnas, C. Wolverton, P. Grones, S. Tan, G. Molnar,
    M. De Angelis, H. Goodman, N. Capstaff, L. JPB, J. Mullen, R. Hangarter, J. Friml,
    S. Kepinski, Nature Plants 9 (2023) 1500–1513.
date_created: 2023-09-15T09:56:01Z
date_published: 2023-09-01T00:00:00Z
date_updated: 2023-12-13T12:23:49Z
day: '01'
ddc:
- '580'
department:
- _id: JiFr
doi: 10.1038/s41477-023-01478-x
external_id:
  isi:
  - '001069238800014'
  pmid:
  - '37666965'
file:
- access_level: open_access
  checksum: 3d6d5d5abb937c14a5f6f0afba3b8624
  content_type: application/pdf
  creator: dernst
  date_created: 2023-09-20T10:51:31Z
  date_updated: 2023-09-20T10:51:31Z
  file_id: '14351'
  file_name: 2023_NaturePlants_Roychoudhry.pdf
  file_size: 9647103
  relation: main_file
  success: 1
file_date_updated: 2023-09-20T10:51:31Z
has_accepted_license: '1'
intvolume: '         9'
isi: 1
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
page: 1500-1513
pmid: 1
publication: Nature Plants
publication_identifier:
  issn:
  - 2055-0278
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
status: public
title: Antigravitropic PIN polarization maintains non-vertical growth in lateral roots
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 9
year: '2023'
...
---
_id: '14341'
abstract:
- lang: eng
  text: Flows through pipes and channels are, in practice, almost always turbulent,
    and the multiscale eddying motion is responsible for a major part of the encountered
    friction losses and pumping costs1. Conversely, for pulsatile flows, in particular
    for aortic blood flow, turbulence levels remain low despite relatively large peak
    velocities. For aortic blood flow, high turbulence levels are intolerable as they
    would damage the shear-sensitive endothelial cell layer2,3,4,5. Here we show that
    turbulence in ordinary pipe flow is diminished if the flow is driven in a pulsatile
    mode that incorporates all the key features of the cardiac waveform. At Reynolds
    numbers comparable to those of aortic blood flow, turbulence is largely inhibited,
    whereas at much higher speeds, the turbulent drag is reduced by more than 25%.
    This specific operation mode is more efficient when compared with steady driving,
    which is the present situation for virtually all fluid transport processes ranging
    from heating circuits to water, gas and oil pipelines.
acknowledged_ssus:
- _id: M-Shop
- _id: ScienComp
acknowledgement: We acknowledge the assistance of the Miba machine shop and the team
  of the ISTA-HPC cluster. We thank M. Quadrio for the discussions. The work was supported
  by the Simons Foundation (grant no. 662960) and by the Austrian Science Fund (grant
  no. I4188-N30), within Deutsche Forschungsgemeinschaft research unit FOR 2688.
article_processing_charge: No
article_type: original
author:
- first_name: Davide
  full_name: Scarselli, Davide
  id: 40315C30-F248-11E8-B48F-1D18A9856A87
  last_name: Scarselli
  orcid: 0000-0001-5227-4271
- first_name: Jose M
  full_name: Lopez Alonso, Jose M
  id: 40770848-F248-11E8-B48F-1D18A9856A87
  last_name: Lopez Alonso
  orcid: 0000-0002-0384-2022
- first_name: Atul
  full_name: Varshney, Atul
  id: 2A2006B2-F248-11E8-B48F-1D18A9856A87
  last_name: Varshney
  orcid: 0000-0002-3072-5999
- first_name: Björn
  full_name: Hof, Björn
  id: 3A374330-F248-11E8-B48F-1D18A9856A87
  last_name: Hof
  orcid: 0000-0003-2057-2754
citation:
  ama: Scarselli D, Lopez Alonso JM, Varshney A, Hof B. Turbulence suppression by
    cardiac-cycle-inspired driving of pipe flow. <i>Nature</i>. 2023;621(7977):71-74.
    doi:<a href="https://doi.org/10.1038/s41586-023-06399-5">10.1038/s41586-023-06399-5</a>
  apa: Scarselli, D., Lopez Alonso, J. M., Varshney, A., &#38; Hof, B. (2023). Turbulence
    suppression by cardiac-cycle-inspired driving of pipe flow. <i>Nature</i>. Springer
    Nature. <a href="https://doi.org/10.1038/s41586-023-06399-5">https://doi.org/10.1038/s41586-023-06399-5</a>
  chicago: Scarselli, Davide, Jose M Lopez Alonso, Atul Varshney, and Björn Hof. “Turbulence
    Suppression by Cardiac-Cycle-Inspired Driving of Pipe Flow.” <i>Nature</i>. Springer
    Nature, 2023. <a href="https://doi.org/10.1038/s41586-023-06399-5">https://doi.org/10.1038/s41586-023-06399-5</a>.
  ieee: D. Scarselli, J. M. Lopez Alonso, A. Varshney, and B. Hof, “Turbulence suppression
    by cardiac-cycle-inspired driving of pipe flow,” <i>Nature</i>, vol. 621, no.
    7977. Springer Nature, pp. 71–74, 2023.
  ista: Scarselli D, Lopez Alonso JM, Varshney A, Hof B. 2023. Turbulence suppression
    by cardiac-cycle-inspired driving of pipe flow. Nature. 621(7977), 71–74.
  mla: Scarselli, Davide, et al. “Turbulence Suppression by Cardiac-Cycle-Inspired
    Driving of Pipe Flow.” <i>Nature</i>, vol. 621, no. 7977, Springer Nature, 2023,
    pp. 71–74, doi:<a href="https://doi.org/10.1038/s41586-023-06399-5">10.1038/s41586-023-06399-5</a>.
  short: D. Scarselli, J.M. Lopez Alonso, A. Varshney, B. Hof, Nature 621 (2023) 71–74.
date_created: 2023-09-17T22:01:09Z
date_published: 2023-09-07T00:00:00Z
date_updated: 2023-09-20T12:10:22Z
day: '07'
department:
- _id: BjHo
doi: 10.1038/s41586-023-06399-5
external_id:
  pmid:
  - '37673988'
intvolume: '       621'
issue: '7977'
language:
- iso: eng
month: '09'
oa_version: None
page: 71-74
pmid: 1
project:
- _id: 238598C6-32DE-11EA-91FC-C7463DDC885E
  grant_number: '662960'
  name: 'Revisiting the Turbulence Problem Using Statistical Mechanics: Experimental
    Studies on Transitional and Turbulent Flows'
- _id: 238B8092-32DE-11EA-91FC-C7463DDC885E
  call_identifier: FWF
  grant_number: I04188
  name: Instabilities in pulsating pipe flow of Newtonian and complex fluids
publication: Nature
publication_identifier:
  eissn:
  - 1476-4687
  issn:
  - 0028-0836
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
  link:
  - description: News on ISTA website
    relation: press_release
    url: https://www.ista.ac.at/en/news/pumping-like-the-heart/
scopus_import: '1'
status: public
title: Turbulence suppression by cardiac-cycle-inspired driving of pipe flow
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 621
year: '2023'
...
---
_id: '14342'
abstract:
- lang: eng
  text: We propose a simple method to measure nonlinear Kerr refractive index in mid-infrared
    frequency range that avoids using sophisticated infrared detectors. Our approach
    is based on using a near-infrared probe beam which interacts with a mid-IR beam
    via wavelength-non-degenerate cross-phase modulation (XPM). By carefully measuring
    XPM-induced spectral modifications in the probe beam and comparing the experimental
    data with simulation results, we extract the value for the non-degenerate Kerr
    index. Finally, in order to obtain the value of degenerate mid-IR Kerr index,
    we use the well-established two-band formalism of Sheik-Bahae et al., which is
    shown to become particularly simple in the limit of low frequencies. The proposed
    technique is complementary to the conventional techniques, such as z-scan, and
    has the advantage of not requiring any mid-infrared detectors.
acknowledgement: The work was supported by IST Austria. The authors would like to
  gratefully acknowledge the help and assistance of Professor John M. Dudley.
article_number: '091104'
article_processing_charge: Yes (in subscription journal)
article_type: original
arxiv: 1
author:
- first_name: Dusan
  full_name: Lorenc, Dusan
  id: 40D8A3E6-F248-11E8-B48F-1D18A9856A87
  last_name: Lorenc
- first_name: Zhanybek
  full_name: Alpichshev, Zhanybek
  id: 45E67A2A-F248-11E8-B48F-1D18A9856A87
  last_name: Alpichshev
  orcid: 0000-0002-7183-5203
citation:
  ama: Lorenc D, Alpichshev Z. Mid-infrared Kerr index evaluation via cross-phase
    modulation with a near-infrared probe beam. <i>Applied Physics Letters</i>. 2023;123(9).
    doi:<a href="https://doi.org/10.1063/5.0161713">10.1063/5.0161713</a>
  apa: Lorenc, D., &#38; Alpichshev, Z. (2023). Mid-infrared Kerr index evaluation
    via cross-phase modulation with a near-infrared probe beam. <i>Applied Physics
    Letters</i>. AIP Publishing. <a href="https://doi.org/10.1063/5.0161713">https://doi.org/10.1063/5.0161713</a>
  chicago: Lorenc, Dusan, and Zhanybek Alpichshev. “Mid-Infrared Kerr Index Evaluation
    via Cross-Phase Modulation with a near-Infrared Probe Beam.” <i>Applied Physics
    Letters</i>. AIP Publishing, 2023. <a href="https://doi.org/10.1063/5.0161713">https://doi.org/10.1063/5.0161713</a>.
  ieee: D. Lorenc and Z. Alpichshev, “Mid-infrared Kerr index evaluation via cross-phase
    modulation with a near-infrared probe beam,” <i>Applied Physics Letters</i>, vol.
    123, no. 9. AIP Publishing, 2023.
  ista: Lorenc D, Alpichshev Z. 2023. Mid-infrared Kerr index evaluation via cross-phase
    modulation with a near-infrared probe beam. Applied Physics Letters. 123(9), 091104.
  mla: Lorenc, Dusan, and Zhanybek Alpichshev. “Mid-Infrared Kerr Index Evaluation
    via Cross-Phase Modulation with a near-Infrared Probe Beam.” <i>Applied Physics
    Letters</i>, vol. 123, no. 9, 091104, AIP Publishing, 2023, doi:<a href="https://doi.org/10.1063/5.0161713">10.1063/5.0161713</a>.
  short: D. Lorenc, Z. Alpichshev, Applied Physics Letters 123 (2023).
date_created: 2023-09-17T22:01:09Z
date_published: 2023-08-28T00:00:00Z
date_updated: 2023-09-20T11:50:06Z
day: '28'
ddc:
- '530'
department:
- _id: ZhAl
doi: 10.1063/5.0161713
external_id:
  arxiv:
  - '2306.09043'
file:
- access_level: open_access
  checksum: 89a1b604d58b209fec66c6b6f919ac98
  content_type: application/pdf
  creator: dernst
  date_created: 2023-09-20T11:36:16Z
  date_updated: 2023-09-20T11:36:16Z
  file_id: '14353'
  file_name: 2023_ApplPhysLetter_Lorenc.pdf
  file_size: 1486715
  relation: main_file
  success: 1
file_date_updated: 2023-09-20T11:36:16Z
has_accepted_license: '1'
intvolume: '       123'
issue: '9'
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
publication: Applied Physics Letters
publication_identifier:
  issn:
  - 0003-6951
publication_status: published
publisher: AIP Publishing
quality_controlled: '1'
scopus_import: '1'
status: public
title: Mid-infrared Kerr index evaluation via cross-phase modulation with a near-infrared
  probe beam
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 123
year: '2023'
...
---
_id: '14343'
abstract:
- lang: eng
  text: The total energy of an eigenstate in a composite quantum system tends to be
    distributed equally among its constituents. We identify the quantum fluctuation
    around this equipartition principle in the simplest disordered quantum system
    consisting of linear combinations of Wigner matrices. As our main ingredient,
    we prove the Eigenstate Thermalisation Hypothesis and Gaussian fluctuation for
    general quadratic forms of the bulk eigenvectors of Wigner matrices with an arbitrary
    deformation.
acknowledgement: "G.C. and L.E. gratefully acknowledge many discussions with Dominik
  Schröder at the preliminary stage of this project, especially his essential contribution
  to identify the correct generalisation of traceless observables to the deformed
  Wigner ensembles.\r\nL.E. and J.H. acknowledges support by ERC Advanced Grant ‘RMTBeyond’
  No. 101020331."
article_number: e74
article_processing_charge: Yes
article_type: original
arxiv: 1
author:
- first_name: Giorgio
  full_name: Cipolloni, Giorgio
  id: 42198EFA-F248-11E8-B48F-1D18A9856A87
  last_name: Cipolloni
  orcid: 0000-0002-4901-7992
- first_name: László
  full_name: Erdös, László
  id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
  last_name: Erdös
  orcid: 0000-0001-5366-9603
- first_name: Sven Joscha
  full_name: Henheik, Sven Joscha
  id: 31d731d7-d235-11ea-ad11-b50331c8d7fb
  last_name: Henheik
  orcid: 0000-0003-1106-327X
- first_name: Oleksii
  full_name: Kolupaiev, Oleksii
  id: 149b70d4-896a-11ed-bdf8-8c63fd44ca61
  last_name: Kolupaiev
citation:
  ama: Cipolloni G, Erdös L, Henheik SJ, Kolupaiev O. Gaussian fluctuations in the
    equipartition principle for Wigner matrices. <i>Forum of Mathematics, Sigma</i>.
    2023;11. doi:<a href="https://doi.org/10.1017/fms.2023.70">10.1017/fms.2023.70</a>
  apa: Cipolloni, G., Erdös, L., Henheik, S. J., &#38; Kolupaiev, O. (2023). Gaussian
    fluctuations in the equipartition principle for Wigner matrices. <i>Forum of Mathematics,
    Sigma</i>. Cambridge University Press. <a href="https://doi.org/10.1017/fms.2023.70">https://doi.org/10.1017/fms.2023.70</a>
  chicago: Cipolloni, Giorgio, László Erdös, Sven Joscha Henheik, and Oleksii Kolupaiev.
    “Gaussian Fluctuations in the Equipartition Principle for Wigner Matrices.” <i>Forum
    of Mathematics, Sigma</i>. Cambridge University Press, 2023. <a href="https://doi.org/10.1017/fms.2023.70">https://doi.org/10.1017/fms.2023.70</a>.
  ieee: G. Cipolloni, L. Erdös, S. J. Henheik, and O. Kolupaiev, “Gaussian fluctuations
    in the equipartition principle for Wigner matrices,” <i>Forum of Mathematics,
    Sigma</i>, vol. 11. Cambridge University Press, 2023.
  ista: Cipolloni G, Erdös L, Henheik SJ, Kolupaiev O. 2023. Gaussian fluctuations
    in the equipartition principle for Wigner matrices. Forum of Mathematics, Sigma.
    11, e74.
  mla: Cipolloni, Giorgio, et al. “Gaussian Fluctuations in the Equipartition Principle
    for Wigner Matrices.” <i>Forum of Mathematics, Sigma</i>, vol. 11, e74, Cambridge
    University Press, 2023, doi:<a href="https://doi.org/10.1017/fms.2023.70">10.1017/fms.2023.70</a>.
  short: G. Cipolloni, L. Erdös, S.J. Henheik, O. Kolupaiev, Forum of Mathematics,
    Sigma 11 (2023).
date_created: 2023-09-17T22:01:09Z
date_published: 2023-08-23T00:00:00Z
date_updated: 2023-12-13T12:24:23Z
day: '23'
ddc:
- '510'
department:
- _id: LaEr
- _id: GradSch
doi: 10.1017/fms.2023.70
ec_funded: 1
external_id:
  arxiv:
  - '2301.05181'
  isi:
  - '001051980200001'
file:
- access_level: open_access
  checksum: eb747420e6a88a7796fa934151957676
  content_type: application/pdf
  creator: dernst
  date_created: 2023-09-20T11:09:35Z
  date_updated: 2023-09-20T11:09:35Z
  file_id: '14352'
  file_name: 2023_ForumMathematics_Cipolloni.pdf
  file_size: 852652
  relation: main_file
  success: 1
file_date_updated: 2023-09-20T11:09:35Z
has_accepted_license: '1'
intvolume: '        11'
isi: 1
language:
- iso: eng
month: '08'
oa: 1
oa_version: Published Version
project:
- _id: 62796744-2b32-11ec-9570-940b20777f1d
  call_identifier: H2020
  grant_number: '101020331'
  name: Random matrices beyond Wigner-Dyson-Mehta
publication: Forum of Mathematics, Sigma
publication_identifier:
  eissn:
  - 2050-5094
publication_status: published
publisher: Cambridge University Press
quality_controlled: '1'
scopus_import: '1'
status: public
title: Gaussian fluctuations in the equipartition principle for Wigner matrices
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 11
year: '2023'
...
---
_id: '14344'
abstract:
- lang: eng
  text: We study the Hamilton cycle problem with input a random graph G ~ G(n,p) in
    two different settings. In the first one, G is given to us in the form of randomly
    ordered adjacency lists while in the second one, we are given the adjacency matrix
    of G. In each of the two settings we derive a deterministic algorithm that w.h.p.
    either finds a Hamilton cycle or returns a certificate that such a cycle does
    not exist for p = p(n) ≥ 0. The running times of our algorithms are O(n) and  respectively,
    each being best possible in its own setting.
article_processing_charge: No
arxiv: 1
author:
- first_name: Michael
  full_name: Anastos, Michael
  id: 0b2a4358-bb35-11ec-b7b9-e3279b593dbb
  last_name: Anastos
citation:
  ama: 'Anastos M. Fast algorithms for solving the Hamilton cycle problem with high
    probability. In: <i>Proceedings of the Annual ACM-SIAM Symposium on Discrete Algorithms</i>.
    Vol 2023. Society for Industrial and Applied Mathematics; 2023:2286-2323. doi:<a
    href="https://doi.org/10.1137/1.9781611977554.ch88">10.1137/1.9781611977554.ch88</a>'
  apa: 'Anastos, M. (2023). Fast algorithms for solving the Hamilton cycle problem
    with high probability. In <i>Proceedings of the Annual ACM-SIAM Symposium on Discrete
    Algorithms</i> (Vol. 2023, pp. 2286–2323). Florence, Italy: Society for Industrial
    and Applied Mathematics. <a href="https://doi.org/10.1137/1.9781611977554.ch88">https://doi.org/10.1137/1.9781611977554.ch88</a>'
  chicago: Anastos, Michael. “Fast Algorithms for Solving the Hamilton Cycle Problem
    with High Probability.” In <i>Proceedings of the Annual ACM-SIAM Symposium on
    Discrete Algorithms</i>, 2023:2286–2323. Society for Industrial and Applied Mathematics,
    2023. <a href="https://doi.org/10.1137/1.9781611977554.ch88">https://doi.org/10.1137/1.9781611977554.ch88</a>.
  ieee: M. Anastos, “Fast algorithms for solving the Hamilton cycle problem with high
    probability,” in <i>Proceedings of the Annual ACM-SIAM Symposium on Discrete Algorithms</i>,
    Florence, Italy, 2023, vol. 2023, pp. 2286–2323.
  ista: 'Anastos M. 2023. Fast algorithms for solving the Hamilton cycle problem with
    high probability. Proceedings of the Annual ACM-SIAM Symposium on Discrete Algorithms.
    SODA: Symposium on Discrete Algorithms vol. 2023, 2286–2323.'
  mla: Anastos, Michael. “Fast Algorithms for Solving the Hamilton Cycle Problem with
    High Probability.” <i>Proceedings of the Annual ACM-SIAM Symposium on Discrete
    Algorithms</i>, vol. 2023, Society for Industrial and Applied Mathematics, 2023,
    pp. 2286–323, doi:<a href="https://doi.org/10.1137/1.9781611977554.ch88">10.1137/1.9781611977554.ch88</a>.
  short: M. Anastos, in:, Proceedings of the Annual ACM-SIAM Symposium on Discrete
    Algorithms, Society for Industrial and Applied Mathematics, 2023, pp. 2286–2323.
conference:
  end_date: 2023-01-25
  location: Florence, Italy
  name: 'SODA: Symposium on Discrete Algorithms'
  start_date: 2023-01-22
date_created: 2023-09-17T22:01:10Z
date_published: 2023-01-01T00:00:00Z
date_updated: 2023-09-25T09:13:41Z
day: '01'
department:
- _id: MaKw
doi: 10.1137/1.9781611977554.ch88
external_id:
  arxiv:
  - '2111.14759'
intvolume: '      2023'
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.48550/arXiv.2111.14759
month: '01'
oa: 1
oa_version: Preprint
page: 2286-2323
publication: Proceedings of the Annual ACM-SIAM Symposium on Discrete Algorithms
publication_identifier:
  isbn:
  - '9781611977554'
publication_status: published
publisher: Society for Industrial and Applied Mathematics
quality_controlled: '1'
scopus_import: '1'
status: public
title: Fast algorithms for solving the Hamilton cycle problem with high probability
type: conference
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 2023
year: '2023'
...
---
_id: '14345'
abstract:
- lang: eng
  text: For a locally finite set in R2, the order-k Brillouin tessellations form an
    infinite sequence of convex face-to-face tilings of the plane. If the set is coarsely
    dense and generic, then the corresponding infinite sequences of minimum and maximum
    angles are both monotonic in k. As an example, a stationary Poisson point process
    in R2  is locally finite, coarsely dense, and generic with probability one. For
    such a set, the distributions of angles in the Voronoi tessellations, Delaunay
    mosaics, and Brillouin tessellations are independent of the order and can be derived
    from the formula for angles in order-1 Delaunay mosaics given by Miles (Math.
    Biosci. 6, 85–127 (1970)).
acknowledgement: Work by all authors but A. Garber is supported by the European Research
  Council (ERC), Grant No. 788183, by the Wittgenstein Prize, Austrian Science Fund
  (FWF), Grant No. Z 342-N31, and by the DFG Collaborative Research Center TRR 109,
  Austrian Science Fund (FWF), Grant No. I 02979-N35. Work by A. Garber is partially
  supported by the Alexander von Humboldt Foundation.
article_processing_charge: Yes (via OA deal)
article_type: original
arxiv: 1
author:
- first_name: Herbert
  full_name: Edelsbrunner, Herbert
  id: 3FB178DA-F248-11E8-B48F-1D18A9856A87
  last_name: Edelsbrunner
  orcid: 0000-0002-9823-6833
- first_name: Alexey
  full_name: Garber, Alexey
  last_name: Garber
- first_name: Mohadese
  full_name: Ghafari, Mohadese
  last_name: Ghafari
- first_name: Teresa
  full_name: Heiss, Teresa
  id: 4879BB4E-F248-11E8-B48F-1D18A9856A87
  last_name: Heiss
  orcid: 0000-0002-1780-2689
- first_name: Morteza
  full_name: Saghafian, Morteza
  id: f86f7148-b140-11ec-9577-95435b8df824
  last_name: Saghafian
citation:
  ama: Edelsbrunner H, Garber A, Ghafari M, Heiss T, Saghafian M. On angles in higher
    order Brillouin tessellations and related tilings in the plane. <i>Discrete and
    Computational Geometry</i>. 2023. doi:<a href="https://doi.org/10.1007/s00454-023-00566-1">10.1007/s00454-023-00566-1</a>
  apa: Edelsbrunner, H., Garber, A., Ghafari, M., Heiss, T., &#38; Saghafian, M. (2023).
    On angles in higher order Brillouin tessellations and related tilings in the plane.
    <i>Discrete and Computational Geometry</i>. Springer Nature. <a href="https://doi.org/10.1007/s00454-023-00566-1">https://doi.org/10.1007/s00454-023-00566-1</a>
  chicago: Edelsbrunner, Herbert, Alexey Garber, Mohadese Ghafari, Teresa Heiss, and
    Morteza Saghafian. “On Angles in Higher Order Brillouin Tessellations and Related
    Tilings in the Plane.” <i>Discrete and Computational Geometry</i>. Springer Nature,
    2023. <a href="https://doi.org/10.1007/s00454-023-00566-1">https://doi.org/10.1007/s00454-023-00566-1</a>.
  ieee: H. Edelsbrunner, A. Garber, M. Ghafari, T. Heiss, and M. Saghafian, “On angles
    in higher order Brillouin tessellations and related tilings in the plane,” <i>Discrete
    and Computational Geometry</i>. Springer Nature, 2023.
  ista: Edelsbrunner H, Garber A, Ghafari M, Heiss T, Saghafian M. 2023. On angles
    in higher order Brillouin tessellations and related tilings in the plane. Discrete
    and Computational Geometry.
  mla: Edelsbrunner, Herbert, et al. “On Angles in Higher Order Brillouin Tessellations
    and Related Tilings in the Plane.” <i>Discrete and Computational Geometry</i>,
    Springer Nature, 2023, doi:<a href="https://doi.org/10.1007/s00454-023-00566-1">10.1007/s00454-023-00566-1</a>.
  short: H. Edelsbrunner, A. Garber, M. Ghafari, T. Heiss, M. Saghafian, Discrete
    and Computational Geometry (2023).
date_created: 2023-09-17T22:01:10Z
date_published: 2023-09-07T00:00:00Z
date_updated: 2023-12-13T12:25:06Z
day: '07'
department:
- _id: HeEd
doi: 10.1007/s00454-023-00566-1
ec_funded: 1
external_id:
  arxiv:
  - '2204.01076'
  isi:
  - '001060727600004'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: https://doi.org/10.1007/s00454-023-00566-1
month: '09'
oa: 1
oa_version: Published Version
project:
- _id: 266A2E9E-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '788183'
  name: Alpha Shape Theory Extended
- _id: 268116B8-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: Z00342
  name: The Wittgenstein Prize
- _id: 2561EBF4-B435-11E9-9278-68D0E5697425
  call_identifier: FWF
  grant_number: I02979-N35
  name: Persistence and stability of geometric complexes
publication: Discrete and Computational Geometry
publication_identifier:
  eissn:
  - 1432-0444
  issn:
  - 0179-5376
publication_status: epub_ahead
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: On angles in higher order Brillouin tessellations and related tilings in the
  plane
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
year: '2023'
...
---
_id: '14360'
abstract:
- lang: eng
  text: To navigate through diverse tissues, migrating cells must balance persistent
    self-propelled motion with adaptive behaviors to circumvent obstacles. We identify
    a curvature-sensing mechanism underlying obstacle evasion in immune-like cells.
    Specifically, we propose that actin polymerization at the advancing edge of migrating
    cells is inhibited by the curvature-sensitive BAR domain protein Snx33 in regions
    with inward plasma membrane curvature. The genetic perturbation of this machinery
    reduces the cells’ capacity to evade obstructions combined with faster and more
    persistent cell migration in obstacle-free environments. Our results show how
    cells can read out their surface topography and utilize actin and plasma membrane
    biophysics to interpret their environment, allowing them to adaptively decide
    if they should move ahead or turn away. On the basis of our findings, we propose
    that the natural diversity of BAR domain proteins may allow cells to tune their
    curvature sensing machinery to match the shape characteristics in their environment.
acknowledgement: "We thank Jan Ellenberg, Leanne Strauss, Anusha Gopalan, and Jia
  Hui Li for critical feedback on the manuscript and the Life Science Editors for
  editing assistance. The plasmid with hSnx33 was a kind gift from Duanqing Pei. Cell
  line with GFP-tagged IRSp53 was a kind gift from Orion Weiner. We thank Brian Graziano
  for providing protocols, reagents, and key advice to generate CRISPR knockout HL-60
  cells. We thank the EMBL flow cytometry core facility, the EMBL advanced light microscopy
  facility, the EMBL proteomics facility, and the EMBL genomics core facility for
  support and advice. We thank Anusha Gopalan and Martin Bergert for their support
  during mechanical measurements by AFM. We thank Estela Sosa Osorio for technical
  assistance for the co-immunoprecipitation. We thank the EMBL genome biology computational
  support (and specially Charles Girardot and Jelle Scholtalbers) for critical assistance
  during RNAseq analysis. We thank Hans Kristian Hannibal‐Bach for his technical assistance
  during the lipidomic analysis of plasma membrane isolates. We thank Steffen Burgold
  for their support with LLS7 microscope in the ZEISS Microscopy Customer Center Europe.
  We acknowledge the financial support of the European Molecular Biology Laboratory
  (EMBL) to A.D.-M., Y.S., A.K., and A.E., the EMBL Interdisciplinary Postdocs (EIPOD)
  program under Marie Sklodowska-Curie COFUND actions MSCA-COFUND-FP to M.S.B. and
  M. S. (grant agreement number: 847543), the BEST program funding by FCT (SFRH/BEST/150300/2019)
  to S.D.A. and the Joachim Herz Stiftung Add-on Fellowship for Interdisciplinary
  Science to E.S.\r\nOpen Access funding enabled and organized by Projekt DEAL."
article_number: '5644'
article_processing_charge: Yes (via OA deal)
article_type: original
author:
- first_name: Ewa
  full_name: Sitarska, Ewa
  last_name: Sitarska
- first_name: Silvia Dias
  full_name: Almeida, Silvia Dias
  last_name: Almeida
- first_name: Marianne Sandvold
  full_name: Beckwith, Marianne Sandvold
  last_name: Beckwith
- first_name: Julian A
  full_name: Stopp, Julian A
  id: 489E3F00-F248-11E8-B48F-1D18A9856A87
  last_name: Stopp
- first_name: Jakub
  full_name: Czuchnowski, Jakub
  last_name: Czuchnowski
- first_name: Marc
  full_name: Siggel, Marc
  last_name: Siggel
- first_name: Rita
  full_name: Roessner, Rita
  last_name: Roessner
- first_name: Aline
  full_name: Tschanz, Aline
  last_name: Tschanz
- first_name: Christer
  full_name: Ejsing, Christer
  last_name: Ejsing
- first_name: Yannick
  full_name: Schwab, Yannick
  last_name: Schwab
- first_name: Jan
  full_name: Kosinski, Jan
  last_name: Kosinski
- first_name: Michael K
  full_name: Sixt, Michael K
  id: 41E9FBEA-F248-11E8-B48F-1D18A9856A87
  last_name: Sixt
  orcid: 0000-0002-6620-9179
- first_name: Anna
  full_name: Kreshuk, Anna
  last_name: Kreshuk
- first_name: Anna
  full_name: Erzberger, Anna
  last_name: Erzberger
- first_name: Alba
  full_name: Diz-Muñoz, Alba
  last_name: Diz-Muñoz
citation:
  ama: Sitarska E, Almeida SD, Beckwith MS, et al. Sensing their plasma membrane curvature
    allows migrating cells to circumvent obstacles. <i>Nature Communications</i>.
    2023;14. doi:<a href="https://doi.org/10.1038/s41467-023-41173-1">10.1038/s41467-023-41173-1</a>
  apa: Sitarska, E., Almeida, S. D., Beckwith, M. S., Stopp, J. A., Czuchnowski, J.,
    Siggel, M., … Diz-Muñoz, A. (2023). Sensing their plasma membrane curvature allows
    migrating cells to circumvent obstacles. <i>Nature Communications</i>. Springer
    Nature. <a href="https://doi.org/10.1038/s41467-023-41173-1">https://doi.org/10.1038/s41467-023-41173-1</a>
  chicago: Sitarska, Ewa, Silvia Dias Almeida, Marianne Sandvold Beckwith, Julian
    A Stopp, Jakub Czuchnowski, Marc Siggel, Rita Roessner, et al. “Sensing Their
    Plasma Membrane Curvature Allows Migrating Cells to Circumvent Obstacles.” <i>Nature
    Communications</i>. Springer Nature, 2023. <a href="https://doi.org/10.1038/s41467-023-41173-1">https://doi.org/10.1038/s41467-023-41173-1</a>.
  ieee: E. Sitarska <i>et al.</i>, “Sensing their plasma membrane curvature allows
    migrating cells to circumvent obstacles,” <i>Nature Communications</i>, vol. 14.
    Springer Nature, 2023.
  ista: Sitarska E, Almeida SD, Beckwith MS, Stopp JA, Czuchnowski J, Siggel M, Roessner
    R, Tschanz A, Ejsing C, Schwab Y, Kosinski J, Sixt MK, Kreshuk A, Erzberger A,
    Diz-Muñoz A. 2023. Sensing their plasma membrane curvature allows migrating cells
    to circumvent obstacles. Nature Communications. 14, 5644.
  mla: Sitarska, Ewa, et al. “Sensing Their Plasma Membrane Curvature Allows Migrating
    Cells to Circumvent Obstacles.” <i>Nature Communications</i>, vol. 14, 5644, Springer
    Nature, 2023, doi:<a href="https://doi.org/10.1038/s41467-023-41173-1">10.1038/s41467-023-41173-1</a>.
  short: E. Sitarska, S.D. Almeida, M.S. Beckwith, J.A. Stopp, J. Czuchnowski, M.
    Siggel, R. Roessner, A. Tschanz, C. Ejsing, Y. Schwab, J. Kosinski, M.K. Sixt,
    A. Kreshuk, A. Erzberger, A. Diz-Muñoz, Nature Communications 14 (2023).
date_created: 2023-09-24T22:01:10Z
date_published: 2023-09-13T00:00:00Z
date_updated: 2023-12-21T14:30:01Z
day: '13'
ddc:
- '570'
department:
- _id: MiSi
doi: 10.1038/s41467-023-41173-1
external_id:
  isi:
  - '001087583700008'
  pmid:
  - '37704612'
file:
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intvolume: '        14'
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language:
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month: '09'
oa: 1
oa_version: Published Version
pmid: 1
publication: Nature Communications
publication_identifier:
  eissn:
  - 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
related_material:
  record:
  - id: '14697'
    relation: dissertation_contains
    status: public
scopus_import: '1'
status: public
title: Sensing their plasma membrane curvature allows migrating cells to circumvent
  obstacles
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 14
year: '2023'
...
---
_id: '14361'
abstract:
- lang: eng
  text: Whether one considers swarming insects, flocking birds, or bacterial colonies,
    collective motion arises from the coordination of individuals and entails the
    adjustment of their respective velocities. In particular, in close confinements,
    such as those encountered by dense cell populations during development or regeneration,
    collective migration can only arise coordinately. Yet, how individuals unify their
    velocities is often not understood. Focusing on a finite number of cells in circular
    confinements, we identify waves of polymerizing actin that function as a pacemaker
    governing the speed of individual cells. We show that the onset of collective
    motion coincides with the synchronization of the wave nucleation frequencies across
    the population. Employing a simpler and more readily accessible mechanical model
    system of active spheres, we identify the synchronization of the individuals’
    internal oscillators as one of the essential requirements to reach the corresponding
    collective state. The mechanical ‘toy’ experiment illustrates that the global
    synchronous state is achieved by nearest neighbor coupling. We suggest by analogy
    that local coupling and the synchronization of actin waves are essential for the
    emergent, self-organized motion of cell collectives.
acknowledged_ssus:
- _id: Bio
- _id: LifeSc
- _id: M-Shop
acknowledgement: We thank K. O’Keeffe, E. Hannezo, P. Devreotes, C. Dessalles, and
  E. Martens for discussion and/or critical reading of the manuscript; the Bioimaging
  Facility of ISTA for excellent support, as well as the Life Science Facility and
  the Miba Machine Shop of ISTA. This work was supported by the European Research
  Council (ERC StG 281556 and CoG 724373) to M.S.
article_number: '5633'
article_processing_charge: Yes
article_type: original
author:
- first_name: Michael
  full_name: Riedl, Michael
  id: 3BE60946-F248-11E8-B48F-1D18A9856A87
  last_name: Riedl
  orcid: 0000-0003-4844-6311
- first_name: Isabelle D
  full_name: Mayer, Isabelle D
  id: 61763940-15b2-11ec-abd3-cfaddfbc66b4
  last_name: Mayer
- first_name: Jack
  full_name: Merrin, Jack
  id: 4515C308-F248-11E8-B48F-1D18A9856A87
  last_name: Merrin
  orcid: 0000-0001-5145-4609
- first_name: Michael K
  full_name: Sixt, Michael K
  id: 41E9FBEA-F248-11E8-B48F-1D18A9856A87
  last_name: Sixt
  orcid: 0000-0002-6620-9179
- first_name: Björn
  full_name: Hof, Björn
  id: 3A374330-F248-11E8-B48F-1D18A9856A87
  last_name: Hof
  orcid: 0000-0003-2057-2754
citation:
  ama: Riedl M, Mayer ID, Merrin J, Sixt MK, Hof B. Synchronization in collectively
    moving inanimate and living active matter. <i>Nature Communications</i>. 2023;14.
    doi:<a href="https://doi.org/10.1038/s41467-023-41432-1">10.1038/s41467-023-41432-1</a>
  apa: Riedl, M., Mayer, I. D., Merrin, J., Sixt, M. K., &#38; Hof, B. (2023). Synchronization
    in collectively moving inanimate and living active matter. <i>Nature Communications</i>.
    Springer Nature. <a href="https://doi.org/10.1038/s41467-023-41432-1">https://doi.org/10.1038/s41467-023-41432-1</a>
  chicago: Riedl, Michael, Isabelle D Mayer, Jack Merrin, Michael K Sixt, and Björn
    Hof. “Synchronization in Collectively Moving Inanimate and Living Active Matter.”
    <i>Nature Communications</i>. Springer Nature, 2023. <a href="https://doi.org/10.1038/s41467-023-41432-1">https://doi.org/10.1038/s41467-023-41432-1</a>.
  ieee: M. Riedl, I. D. Mayer, J. Merrin, M. K. Sixt, and B. Hof, “Synchronization
    in collectively moving inanimate and living active matter,” <i>Nature Communications</i>,
    vol. 14. Springer Nature, 2023.
  ista: Riedl M, Mayer ID, Merrin J, Sixt MK, Hof B. 2023. Synchronization in collectively
    moving inanimate and living active matter. Nature Communications. 14, 5633.
  mla: Riedl, Michael, et al. “Synchronization in Collectively Moving Inanimate and
    Living Active Matter.” <i>Nature Communications</i>, vol. 14, 5633, Springer Nature,
    2023, doi:<a href="https://doi.org/10.1038/s41467-023-41432-1">10.1038/s41467-023-41432-1</a>.
  short: M. Riedl, I.D. Mayer, J. Merrin, M.K. Sixt, B. Hof, Nature Communications
    14 (2023).
date_created: 2023-09-24T22:01:10Z
date_published: 2023-09-13T00:00:00Z
date_updated: 2023-12-13T12:29:41Z
day: '13'
ddc:
- '530'
- '570'
department:
- _id: MiSi
- _id: NanoFab
- _id: BjHo
doi: 10.1038/s41467-023-41432-1
ec_funded: 1
external_id:
  isi:
  - '001087583700030'
  pmid:
  - '37704595'
file:
- access_level: open_access
  checksum: 82d2d4ad736cc8493db8ce45cd313f7b
  content_type: application/pdf
  creator: dernst
  date_created: 2023-09-25T08:32:37Z
  date_updated: 2023-09-25T08:32:37Z
  file_id: '14366'
  file_name: 2023_NatureComm_Riedl.pdf
  file_size: 2317272
  relation: main_file
  success: 1
file_date_updated: 2023-09-25T08:32:37Z
has_accepted_license: '1'
intvolume: '        14'
isi: 1
language:
- iso: eng
month: '09'
oa: 1
oa_version: Published Version
pmid: 1
project:
- _id: 25A603A2-B435-11E9-9278-68D0E5697425
  call_identifier: FP7
  grant_number: '281556'
  name: Cytoskeletal force generation and force transduction of migrating leukocytes
- _id: 25FE9508-B435-11E9-9278-68D0E5697425
  call_identifier: H2020
  grant_number: '724373'
  name: Cellular navigation along spatial gradients
publication: Nature Communications
publication_identifier:
  eissn:
  - 2041-1723
publication_status: published
publisher: Springer Nature
quality_controlled: '1'
scopus_import: '1'
status: public
title: Synchronization in collectively moving inanimate and living active matter
tmp:
  image: /images/cc_by.png
  legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
  name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
  short: CC BY (4.0)
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 14
year: '2023'
...
---
_id: '14362'
abstract:
- lang: eng
  text: "Motivated by recent applications to entropy theory in dynamical systems,
    we generalise notions introduced by Matthews and define weakly weighted and componentwise
    weakly weighted (generalised) quasi-metrics. We then systematise and extend to
    full generality the correspondences between these objects and other structures
    arising in theoretical computer science and dynamics. In particular, we study
    the correspondences with weak partial metrics and, if the underlying space is
    a semilattice, with invariant (generalised) quasi-metrics satisfying the descending
    path condition, and with strictly monotone semi(-co-)valuations.\r\nWe conclude
    discussing, for endomorphisms of generalised quasi-metric semilattices, a generalisation
    of both the known intrinsic semilattice entropy and the semigroup entropy."
article_number: '114129'
article_processing_charge: No
article_type: original
arxiv: 1
author:
- first_name: Ilaria
  full_name: Castellano, Ilaria
  last_name: Castellano
- first_name: Anna
  full_name: Giordano Bruno, Anna
  last_name: Giordano Bruno
- first_name: Nicolò
  full_name: Zava, Nicolò
  id: c8b3499c-7a77-11eb-b046-aa368cbbf2ad
  last_name: Zava
  orcid: 0000-0001-8686-1888
citation:
  ama: Castellano I, Giordano Bruno A, Zava N. Weakly weighted generalised quasi-metric
    spaces and semilattices. <i>Theoretical Computer Science</i>. 2023;977. doi:<a
    href="https://doi.org/10.1016/j.tcs.2023.114129">10.1016/j.tcs.2023.114129</a>
  apa: Castellano, I., Giordano Bruno, A., &#38; Zava, N. (2023). Weakly weighted
    generalised quasi-metric spaces and semilattices. <i>Theoretical Computer Science</i>.
    Elsevier. <a href="https://doi.org/10.1016/j.tcs.2023.114129">https://doi.org/10.1016/j.tcs.2023.114129</a>
  chicago: Castellano, Ilaria, Anna Giordano Bruno, and Nicolò Zava. “Weakly Weighted
    Generalised Quasi-Metric Spaces and Semilattices.” <i>Theoretical Computer Science</i>.
    Elsevier, 2023. <a href="https://doi.org/10.1016/j.tcs.2023.114129">https://doi.org/10.1016/j.tcs.2023.114129</a>.
  ieee: I. Castellano, A. Giordano Bruno, and N. Zava, “Weakly weighted generalised
    quasi-metric spaces and semilattices,” <i>Theoretical Computer Science</i>, vol.
    977. Elsevier, 2023.
  ista: Castellano I, Giordano Bruno A, Zava N. 2023. Weakly weighted generalised
    quasi-metric spaces and semilattices. Theoretical Computer Science. 977, 114129.
  mla: Castellano, Ilaria, et al. “Weakly Weighted Generalised Quasi-Metric Spaces
    and Semilattices.” <i>Theoretical Computer Science</i>, vol. 977, 114129, Elsevier,
    2023, doi:<a href="https://doi.org/10.1016/j.tcs.2023.114129">10.1016/j.tcs.2023.114129</a>.
  short: I. Castellano, A. Giordano Bruno, N. Zava, Theoretical Computer Science 977
    (2023).
date_created: 2023-09-24T22:01:11Z
date_published: 2023-10-25T00:00:00Z
date_updated: 2024-01-30T13:22:04Z
day: '25'
department:
- _id: HeEd
doi: 10.1016/j.tcs.2023.114129
external_id:
  arxiv:
  - '2212.08424'
  isi:
  - '001076934000001'
intvolume: '       977'
isi: 1
language:
- iso: eng
main_file_link:
- open_access: '1'
  url: 'https://doi.org/10.48550/arXiv.2212.08424 '
month: '10'
oa: 1
oa_version: Preprint
publication: Theoretical Computer Science
publication_identifier:
  issn:
  - 0304-3975
publication_status: published
publisher: Elsevier
quality_controlled: '1'
scopus_import: '1'
status: public
title: Weakly weighted generalised quasi-metric spaces and semilattices
type: journal_article
user_id: 2DF688A6-F248-11E8-B48F-1D18A9856A87
volume: 977
year: '2023'
...
