---
_id: '2461'
author:
- first_name: Michael
full_name: Sauer, Michael
last_name: Sauer
- first_name: Jirí
full_name: Friml, Jirí
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
citation:
ama: Sauer M, Friml J. The Matryoshka dolls of plant polarity. Development.
2004;131(23):5774-5775. doi:10.1242/dev.01463
apa: Sauer, M., & Friml, J. (2004). The Matryoshka dolls of plant polarity.
Development. Company of Biologists. https://doi.org/10.1242/dev.01463
chicago: Sauer, Michael, and Jiří Friml. “The Matryoshka Dolls of Plant Polarity.”
Development. Company of Biologists, 2004. https://doi.org/10.1242/dev.01463.
ieee: M. Sauer and J. Friml, “The Matryoshka dolls of plant polarity,” Development,
vol. 131, no. 23. Company of Biologists, pp. 5774–5775, 2004.
ista: Sauer M, Friml J. 2004. The Matryoshka dolls of plant polarity. Development.
131(23), 5774–5775.
mla: Sauer, Michael, and Jiří Friml. “The Matryoshka Dolls of Plant Polarity.” Development,
vol. 131, no. 23, Company of Biologists, 2004, pp. 5774–75, doi:10.1242/dev.01463.
short: M. Sauer, J. Friml, Development 131 (2004) 5774–5775.
date_created: 2018-12-11T11:57:48Z
date_published: 2004-12-01T00:00:00Z
date_updated: 2021-01-12T06:57:37Z
day: '01'
doi: 10.1242/dev.01463
extern: '1'
intvolume: ' 131'
issue: '23'
language:
- iso: eng
month: '12'
oa_version: None
page: 5774 - 5775
publication: Development
publication_status: published
publisher: Company of Biologists
publist_id: '4442'
quality_controlled: '1'
status: public
title: The Matryoshka dolls of plant polarity
type: review
user_id: 3E5EF7F0-F248-11E8-B48F-1D18A9856A87
volume: 131
year: '2004'
...
---
_id: '2636'
author:
- first_name: Akiko
full_name: Momiyama, Akiko
last_name: Momiyama
- first_name: Ryuichi
full_name: Ryuichi Shigemoto
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
citation:
ama: Momiyama A, Shigemoto R. Function and distribution of glutamate receptors in
the central synapses. Tanpakushitsu kakusan koso Protein nucleic acid enzyme.
2004;49(3 Suppl):287-294.
apa: Momiyama, A., & Shigemoto, R. (2004). Function and distribution of glutamate
receptors in the central synapses. Tanpakushitsu Kakusan Koso Protein Nucleic
Acid Enzyme. Kyoritsu Shuppan.
chicago: Momiyama, Akiko, and Ryuichi Shigemoto. “Function and Distribution of Glutamate
Receptors in the Central Synapses.” Tanpakushitsu Kakusan Koso Protein Nucleic
Acid Enzyme. Kyoritsu Shuppan, 2004.
ieee: A. Momiyama and R. Shigemoto, “Function and distribution of glutamate receptors
in the central synapses,” Tanpakushitsu kakusan koso Protein nucleic acid enzyme,
vol. 49, no. 3 Suppl. Kyoritsu Shuppan, pp. 287–294, 2004.
ista: Momiyama A, Shigemoto R. 2004. Function and distribution of glutamate receptors
in the central synapses. Tanpakushitsu kakusan koso Protein nucleic acid enzyme.
49(3 Suppl), 287–294.
mla: Momiyama, Akiko, and Ryuichi Shigemoto. “Function and Distribution of Glutamate
Receptors in the Central Synapses.” Tanpakushitsu Kakusan Koso Protein Nucleic
Acid Enzyme, vol. 49, no. 3 Suppl, Kyoritsu Shuppan, 2004, pp. 287–94.
short: A. Momiyama, R. Shigemoto, Tanpakushitsu Kakusan Koso Protein Nucleic Acid
Enzyme 49 (2004) 287–294.
date_created: 2018-12-11T11:58:48Z
date_published: 2004-02-01T00:00:00Z
date_updated: 2020-07-14T12:45:44Z
day: '01'
extern: 1
intvolume: ' 49'
issue: 3 Suppl
month: '02'
page: 287 - 294
publication: Tanpakushitsu kakusan koso Protein nucleic acid enzyme
publication_status: published
publisher: Kyoritsu Shuppan
publist_id: '4261'
quality_controlled: 0
status: public
title: Function and distribution of glutamate receptors in the central synapses
type: review
volume: 49
year: '2004'
...
---
_id: '2638'
abstract:
- lang: eng
text: Among various types of low- and high-threshold calcium channels, the high
voltage-activated P/Q-type channel is the most abundant in the cerebellum. These
P/Q-type channels are involved in the regulation of neurotransmitter release and
in the integration of dendritic inputs. We used an antibody specific for the α1A
subunit of the P/Q-type channel in quantitative pre-embedding immunogold labelling
combined with three-dimensional reconstruction to reveal the subcellular distribution
of pre- and postsynaptic P/Q-type channels in the rat cerebellum. At the light
microscopic level, immunoreactivity for the α1A protein was prevalent in the molecular
layer, whereas immunostaining was moderate in the somata of Purkinje cells and
weak in the granule cell layer. At the electron microscopic level, the most intense
Immunoreactivity for the α1A subunit was found in the presynaptic active zone
of parallel fibre varicosities. The dendritic spines of Purkinje cells were also
strongly labelled with the highest density of immunoparticles detected within
180 nm from the edge of the asymmetrical parallel fibre-Purkinje cell synapses.
By contrast, the immunolabelling was sparse in climbing fibre varicosities and
axon terminals of GABAergic cells, and weak and diffuse in dendritic shafts of
Purkinje cells. The association of the α1A subunit with the glutamatergic parallel
fibre-Purkinje cell synapses suggests that presynaptic channels have a major role
in the mediation of excitatory neurotransmission, whereas postsynaptic channels
are likely to be involved in depolarization-induced generation of local calcium
transients in Purkinje cells.
author:
- first_name: Ákos
full_name: Kulik, Ákos
last_name: Kulik
- first_name: Kazuhiko
full_name: Nakadate, Kazuhiko
last_name: Nakadate
- first_name: Akari
full_name: Hagiwara, Akari
last_name: Hagiwara
- first_name: Yugo
full_name: Fukazawa, Yugo
last_name: Fukazawa
- first_name: Rafael
full_name: Luján, Rafael
last_name: Luján
- first_name: Hiromitsu
full_name: Saito, Hiromitsu
last_name: Saito
- first_name: Noboru
full_name: Suzuki, Noboru
last_name: Suzuki
- first_name: Akira
full_name: Futatsugi, Akira
last_name: Futatsugi
- first_name: Katsuhiko
full_name: Mikoshiba, Katsuhiko
last_name: Mikoshiba
- first_name: Michael
full_name: Frotscher, Michael
last_name: Frotscher
- first_name: Ryuichi
full_name: Ryuichi Shigemoto
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
citation:
ama: Kulik Á, Nakadate K, Hagiwara A, et al. Immunocytochemical localization of
the α1A subunit of the P/Q-type calcium channel in the rat cerebellum. European
Journal of Neuroscience. 2004;19(8):2169-2178. doi:10.1111/j.0953-816X.2004.03319.x
apa: Kulik, Á., Nakadate, K., Hagiwara, A., Fukazawa, Y., Luján, R., Saito, H.,
… Shigemoto, R. (2004). Immunocytochemical localization of the α1A subunit of
the P/Q-type calcium channel in the rat cerebellum. European Journal of Neuroscience.
Wiley-Blackwell. https://doi.org/10.1111/j.0953-816X.2004.03319.x
chicago: Kulik, Ákos, Kazuhiko Nakadate, Akari Hagiwara, Yugo Fukazawa, Rafael Luján,
Hiromitsu Saito, Noboru Suzuki, et al. “Immunocytochemical Localization of the
Α1A Subunit of the P/Q-Type Calcium Channel in the Rat Cerebellum.” European
Journal of Neuroscience. Wiley-Blackwell, 2004. https://doi.org/10.1111/j.0953-816X.2004.03319.x.
ieee: Á. Kulik et al., “Immunocytochemical localization of the α1A subunit
of the P/Q-type calcium channel in the rat cerebellum,” European Journal of
Neuroscience, vol. 19, no. 8. Wiley-Blackwell, pp. 2169–2178, 2004.
ista: Kulik Á, Nakadate K, Hagiwara A, Fukazawa Y, Luján R, Saito H, Suzuki N, Futatsugi
A, Mikoshiba K, Frotscher M, Shigemoto R. 2004. Immunocytochemical localization
of the α1A subunit of the P/Q-type calcium channel in the rat cerebellum. European
Journal of Neuroscience. 19(8), 2169–2178.
mla: Kulik, Ákos, et al. “Immunocytochemical Localization of the Α1A Subunit of
the P/Q-Type Calcium Channel in the Rat Cerebellum.” European Journal of Neuroscience,
vol. 19, no. 8, Wiley-Blackwell, 2004, pp. 2169–78, doi:10.1111/j.0953-816X.2004.03319.x.
short: Á. Kulik, K. Nakadate, A. Hagiwara, Y. Fukazawa, R. Luján, H. Saito, N. Suzuki,
A. Futatsugi, K. Mikoshiba, M. Frotscher, R. Shigemoto, European Journal of Neuroscience
19 (2004) 2169–2178.
date_created: 2018-12-11T11:58:48Z
date_published: 2004-04-01T00:00:00Z
date_updated: 2021-01-12T06:58:44Z
day: '01'
doi: 10.1111/j.0953-816X.2004.03319.x
extern: 1
intvolume: ' 19'
issue: '8'
month: '04'
page: 2169 - 2178
publication: European Journal of Neuroscience
publication_status: published
publisher: Wiley-Blackwell
publist_id: '4259'
quality_controlled: 0
status: public
title: Immunocytochemical localization of the α1A subunit of the P/Q-type calcium
channel in the rat cerebellum
type: journal_article
volume: 19
year: '2004'
...
---
_id: '2639'
abstract:
- lang: eng
text: Vesicular glutamate transporter type 3 (VGLUT3) containing neuronal elements
were characterized using antibodies to VGLUT3 and molecular cell markers. All
VGLUT3-positive somata were immunoreactive for CCK, and very rarely, also for
calbindin; none was positive for parvalbumin, calretinin, VIP or somatostatin.
In the CA1 area, 26.8 ± 0.7% of CCK-positive interneuron somata were VGLUT3-positive,
a nonoverlapping 22.8 ± 1.9% were calbindin-positive, 10.7 ± 2.5% VIP-positive
and the rest were only CCK-positive. The patterns of coexpression were similar
in the CA3 area, the dentate gyrus and the isocortex. Immunoreactivity for VGLUT3
was undetectable in pyramidal and dentate granule cells. Boutons colabelled for
VGLUT3, CCK and GAD were most abundant in the cellular layers of the hippocampus
and in layers II-III of the isocortex. Large VGLUT3-labelled boutons at the border
of strata radiatum and lacunosum-moleculare in the CA1 area were negative for
GAD, but were labelled for vesicular monoamine transporter type 2, plasmalemmal
serotonin transporter or serotonin. No colocalization was found in terminals between
VGLUT3 and parvalbumin, vesicular acetylcholine transporter and group III (mGluR7a,b;
mGluR8a,b) metabotropic glutamate receptors. In stratum radiatum and the isocortex,
VGLUT3-positive but GAD-negative boutons heavily innervated the soma and proximal
dendrites of some VGLUT3- or calbindin-positive interneurons. The results suggest
that boutons coexpressing VGLUT3, CCK and GAD originate from CCK-positive basket
cells, which are VIP-immunonegative. Other VGLUT3-positive boutons immunopositive
for serotonergic markers but negative for GAD probably originate from the median
raphe nucleus and innervate select interneurons. The presumed amino acid substrate
of VGLUT3 may act on presynaptic kainate or group II metabotropic glutamate receptors.
author:
- first_name: Jozsef
full_name: Somogyi, Jozsef
last_name: Somogyi
- first_name: Agnès
full_name: Baude, Agnès
last_name: Baude
- first_name: Yuko
full_name: Omori, Yuko
last_name: Omori
- first_name: Hidemi
full_name: Shimizu, Hidemi
last_name: Shimizu
- first_name: Salah
full_name: El-Mestikawy, Salah
last_name: El Mestikawy
- first_name: Masahiro
full_name: Fukaya, Masahiro
last_name: Fukaya
- first_name: Ryuichi
full_name: Ryuichi Shigemoto
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Masahiko
full_name: Watanabe, Masahiko
last_name: Watanabe
- first_name: Péter
full_name: Somogyi, Péter
last_name: Somogyi
citation:
ama: Somogyi J, Baude A, Omori Y, et al. GABAergic basket cells expressing cholecystokinin
contain vesicular glutamate transporter type 3 (VGLUT3) in their synaptic terminals
in hippocampus and isocortex of the rat. European Journal of Neuroscience.
2004;19(3):552-569. doi:10.1111/j.0953-816X.2003.03091.x
apa: Somogyi, J., Baude, A., Omori, Y., Shimizu, H., El Mestikawy, S., Fukaya, M.,
… Somogyi, P. (2004). GABAergic basket cells expressing cholecystokinin contain
vesicular glutamate transporter type 3 (VGLUT3) in their synaptic terminals in
hippocampus and isocortex of the rat. European Journal of Neuroscience.
Wiley-Blackwell. https://doi.org/10.1111/j.0953-816X.2003.03091.x
chicago: Somogyi, Jozsef, Agnès Baude, Yuko Omori, Hidemi Shimizu, Salah El Mestikawy,
Masahiro Fukaya, Ryuichi Shigemoto, Masahiko Watanabe, and Péter Somogyi. “GABAergic
Basket Cells Expressing Cholecystokinin Contain Vesicular Glutamate Transporter
Type 3 (VGLUT3) in Their Synaptic Terminals in Hippocampus and Isocortex of the
Rat.” European Journal of Neuroscience. Wiley-Blackwell, 2004. https://doi.org/10.1111/j.0953-816X.2003.03091.x.
ieee: J. Somogyi et al., “GABAergic basket cells expressing cholecystokinin
contain vesicular glutamate transporter type 3 (VGLUT3) in their synaptic terminals
in hippocampus and isocortex of the rat,” European Journal of Neuroscience,
vol. 19, no. 3. Wiley-Blackwell, pp. 552–569, 2004.
ista: Somogyi J, Baude A, Omori Y, Shimizu H, El Mestikawy S, Fukaya M, Shigemoto
R, Watanabe M, Somogyi P. 2004. GABAergic basket cells expressing cholecystokinin
contain vesicular glutamate transporter type 3 (VGLUT3) in their synaptic terminals
in hippocampus and isocortex of the rat. European Journal of Neuroscience. 19(3),
552–569.
mla: Somogyi, Jozsef, et al. “GABAergic Basket Cells Expressing Cholecystokinin
Contain Vesicular Glutamate Transporter Type 3 (VGLUT3) in Their Synaptic Terminals
in Hippocampus and Isocortex of the Rat.” European Journal of Neuroscience,
vol. 19, no. 3, Wiley-Blackwell, 2004, pp. 552–69, doi:10.1111/j.0953-816X.2003.03091.x.
short: J. Somogyi, A. Baude, Y. Omori, H. Shimizu, S. El Mestikawy, M. Fukaya, R.
Shigemoto, M. Watanabe, P. Somogyi, European Journal of Neuroscience 19 (2004)
552–569.
date_created: 2018-12-11T11:58:49Z
date_published: 2004-02-01T00:00:00Z
date_updated: 2021-01-12T06:58:44Z
day: '01'
doi: 10.1111/j.0953-816X.2003.03091.x
extern: 1
intvolume: ' 19'
issue: '3'
month: '02'
page: 552 - 569
publication: European Journal of Neuroscience
publication_status: published
publisher: Wiley-Blackwell
publist_id: '4260'
quality_controlled: 0
status: public
title: GABAergic basket cells expressing cholecystokinin contain vesicular glutamate
transporter type 3 (VGLUT3) in their synaptic terminals in hippocampus and isocortex
of the rat
type: journal_article
volume: 19
year: '2004'
...
---
_id: '2640'
abstract:
- lang: eng
text: Hyperpolarization-activated cation currents (Ih) contribute to various physiological
properties and functions in the brain, including neuronal pacemaker activity,
setting of resting membrane potential, and dendritic integration of synaptic input.
Four subunits of the Hyperpolarization-activated and Cyclic-Nucleotide-gated nonselective
cation channels (HCN1-4), which generate Ih, have been cloned recently. To better
understand the functional diversity of Ih in the brain, we examined precise immunohistochemical
localization of four HCNs in the rat brain. Immunoreactivity for HCN1 showed predominantly
cortical distribution, being intense in the neocortex, hippocampus, superior colliculus,
and cerebellum, whereas those for HCN3 and HCN4 exhibited subcortical distribution
mainly concentrated in the hypothalamus and thalamus, respectively. Immunoreactivity
for HCN2 had a widespread distribution throughout the brain. Double immunofluorescence
revealed colocalization of immunoreactivity for HCN1 and HCN2 in distal dendrites
of pyramidal cells in the hippocampus and neocortex. At the electron microscopic
level, immunogold particles for HCN1 and HCN2 had similar distribution patterns
along plasma membrane of dendritic shafts in layer I of the neocortex and stratum
lacunosum moleculare of the hippocampal CA1 area, suggesting that these subunits
could form heteromeric channels. Our results further indicate that HCNs are localized
not only in somato-dendritic compartments but also in axonal compartments of neurons.
Immunoreactivity for HCNs often occurred in preterminal rather than terminal portions
of axons and in specific populations of myelinated axons. We also found HCN2-immunopositive
oligodendrocytes including perineuronal oligodendrocytes throughout the brain.
These results support previous electrophysiological findings and further suggest
unexpected roles of Ih channels in the brain.
author:
- first_name: Takuya
full_name: Notomi, Takuya
last_name: Notomi
- first_name: Ryuichi
full_name: Ryuichi Shigemoto
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
citation:
ama: Notomi T, Shigemoto R. Immunohistochemical localization of Ih channel subunits,
HCN1-4, in the rat brain. Journal of Comparative Neurology. 2004;471(3):241-276.
doi:10.1002/cne.11039
apa: Notomi, T., & Shigemoto, R. (2004). Immunohistochemical localization of
Ih channel subunits, HCN1-4, in the rat brain. Journal of Comparative Neurology.
Wiley-Blackwell. https://doi.org/10.1002/cne.11039
chicago: Notomi, Takuya, and Ryuichi Shigemoto. “Immunohistochemical Localization
of Ih Channel Subunits, HCN1-4, in the Rat Brain.” Journal of Comparative Neurology.
Wiley-Blackwell, 2004. https://doi.org/10.1002/cne.11039.
ieee: T. Notomi and R. Shigemoto, “Immunohistochemical localization of Ih channel
subunits, HCN1-4, in the rat brain,” Journal of Comparative Neurology,
vol. 471, no. 3. Wiley-Blackwell, pp. 241–276, 2004.
ista: Notomi T, Shigemoto R. 2004. Immunohistochemical localization of Ih channel
subunits, HCN1-4, in the rat brain. Journal of Comparative Neurology. 471(3),
241–276.
mla: Notomi, Takuya, and Ryuichi Shigemoto. “Immunohistochemical Localization of
Ih Channel Subunits, HCN1-4, in the Rat Brain.” Journal of Comparative Neurology,
vol. 471, no. 3, Wiley-Blackwell, 2004, pp. 241–76, doi:10.1002/cne.11039.
short: T. Notomi, R. Shigemoto, Journal of Comparative Neurology 471 (2004) 241–276.
date_created: 2018-12-11T11:58:49Z
date_published: 2004-04-05T00:00:00Z
date_updated: 2021-01-12T06:58:45Z
day: '05'
doi: 10.1002/cne.11039
extern: 1
intvolume: ' 471'
issue: '3'
month: '04'
page: 241 - 276
publication: Journal of Comparative Neurology
publication_status: published
publisher: Wiley-Blackwell
publist_id: '4258'
quality_controlled: 0
status: public
title: Immunohistochemical localization of Ih channel subunits, HCN1-4, in the rat
brain
type: journal_article
volume: 471
year: '2004'
...
---
_id: '2641'
abstract:
- lang: eng
text: The Na+-K+ pump current (Ip) and the h-current (Ih) flowing through hyperpolarization-activated
channels (h-channels) participate in generating the resting potential. These two
currents are thought to be produced independently. We show here bidirectional
interactions between Na+-K+ pumps and h-channels in mesencephalic trigeminal neurons.
Activation of Ih leads to the generation of two types of ouabain-sensitive Ip
with temporal profiles similar to those of instantaneous and slow components of
I h, presumably reflecting Na+ transients in a restricted cellular space. Moreover,
the Ip activated by instantaneous I h can facilitate the subsequent activation
of slow Ih. Such counteractive and cooperative interactions were also disclosed
by replacing extracellular Na+ with Li+, which is permeant through h-channels
but does not stimulate the Na+-K+ pump as strongly as Na+ ions. These observations
indicate that the interactions are bidirectional and mediated by Na+ ions. Also
after substitution of extracellular Na+ with Li+, the tail Ih was reduced markedly
despite an enhancement of Ih itself, attributable to a negative shift of the reversal
potential for I h presumably caused by intracellular accumulation of Li+ ions.
This suggests the presence of a microdomain where the interactions can take place.
Thus, the bidirectional interactions between Na+-K + pumps and h-channels are
likely to be mediated by Na+ microdomain. Consistent with these findings, hyperpolarization-activated
and cyclic nucleotide-modulated subunits (HCN1/2) and the Na+-K + pump α3 isoform
were colocalized in plasma membrane of mesencephalic trigeminal neurons having
numerous spines.
author:
- first_name: Youngnam
full_name: Kang, Youngnam
last_name: Kang
- first_name: Takuya
full_name: Notomi, Takuya
last_name: Notomi
- first_name: Mitsuru
full_name: Saito, Mitsuru
last_name: Saito
- first_name: Wei
full_name: Zhang, Wei
last_name: Zhang
- first_name: Ryuichi
full_name: Ryuichi Shigemoto
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
citation:
ama: Kang Y, Notomi T, Saito M, Zhang W, Shigemoto R. Bidirectional interactions
between H-channels and Na+-K + pumps in mesencephalic trigeminal neurons. Journal
of Neuroscience. 2004;24(14):3694-3702. doi:10.1523/JNEUROSCI.5641-03.2004
apa: Kang, Y., Notomi, T., Saito, M., Zhang, W., & Shigemoto, R. (2004). Bidirectional
interactions between H-channels and Na+-K + pumps in mesencephalic trigeminal
neurons. Journal of Neuroscience. Society for Neuroscience. https://doi.org/10.1523/JNEUROSCI.5641-03.2004
chicago: Kang, Youngnam, Takuya Notomi, Mitsuru Saito, Wei Zhang, and Ryuichi Shigemoto.
“Bidirectional Interactions between H-Channels and Na+-K + Pumps in Mesencephalic
Trigeminal Neurons.” Journal of Neuroscience. Society for Neuroscience,
2004. https://doi.org/10.1523/JNEUROSCI.5641-03.2004.
ieee: Y. Kang, T. Notomi, M. Saito, W. Zhang, and R. Shigemoto, “Bidirectional interactions
between H-channels and Na+-K + pumps in mesencephalic trigeminal neurons,” Journal
of Neuroscience, vol. 24, no. 14. Society for Neuroscience, pp. 3694–3702,
2004.
ista: Kang Y, Notomi T, Saito M, Zhang W, Shigemoto R. 2004. Bidirectional interactions
between H-channels and Na+-K + pumps in mesencephalic trigeminal neurons. Journal
of Neuroscience. 24(14), 3694–3702.
mla: Kang, Youngnam, et al. “Bidirectional Interactions between H-Channels and Na+-K
+ Pumps in Mesencephalic Trigeminal Neurons.” Journal of Neuroscience,
vol. 24, no. 14, Society for Neuroscience, 2004, pp. 3694–702, doi:10.1523/JNEUROSCI.5641-03.2004.
short: Y. Kang, T. Notomi, M. Saito, W. Zhang, R. Shigemoto, Journal of Neuroscience
24 (2004) 3694–3702.
date_created: 2018-12-11T11:58:49Z
date_published: 2004-04-07T00:00:00Z
date_updated: 2021-01-12T06:58:45Z
day: '07'
doi: 10.1523/JNEUROSCI.5641-03.2004
extern: 1
intvolume: ' 24'
issue: '14'
month: '04'
page: 3694 - 3702
publication: Journal of Neuroscience
publication_status: published
publisher: Society for Neuroscience
publist_id: '4257'
quality_controlled: 0
status: public
title: Bidirectional interactions between H-channels and Na+-K + pumps in mesencephalic
trigeminal neurons
type: journal_article
volume: 24
year: '2004'
...
---
_id: '2642'
abstract:
- lang: eng
text: In the hippocampal CA1 region, metabotropic glutamate subtype 1 (mGluR1) receptors
have been implicated in a variety of physiological responses to glutamate, which
include modulation of synaptic transmission and plasticity, as well as neuronal
excitability and synchronization. The mGluR1α isoform is characteristically expressed
only by nonprincipal cells, and it is particularly enriched in somatostatin (SS
-containing interneurons in stratum oriens-alveus. Anatomical and physiological
data have indicated the presence of mGluR1α in several distinct classes of interneurons
with their somata located also in strata pyramidale, radiatum, and lacunosum moleculare.
Each different interneuron subtype, as defined by functionally relevant criteria,
including input/output characteristics and expression of selective molecular markers,
subserves distinct functions in local hippocampal circuits. We have investigated
which of the different CA1 interneuron classes express mGluR1α by immunofluorescent
labeling, combining antibodies to mGluR1α, calcium-binding proteins, and neuropeptides,
and by intracellular labeling in vitro. Several types of interneuron that are
immunopositive for mGluR1α each targeted different domains of pyramidal cells
and included (1) O-LM interneurons, found to coexpress both SS and parvalbumin
(PV); (2) interneurons with target selectivity for other interneurons, expressing
vasoactive intestinal polypeptide (VIP) and/or the calcium-binding protein calretinin;
(3) procholecystokinin-immunopositive interneurons probably non-basket and dendrite-targeting;
and (4) an as-yet unidentified SS-immunoreactive but PV-immunonegative interneuron
class, possibly corresponding to oriensbistratified cells. Estimation of the relative
proportion of mGluR1α-positive interneurons showed 43%, 46%, and 30% co-labeling
with SS, VIP, or PV, respectively. The identification of the specific subclasses
of CA1 interneurons expressing mGluR1α provides the network basis for assessing
the contribution of this receptor to the excitability of the hippocampus.
author:
- first_name: Francesco
full_name: Ferraguti, Francesco
last_name: Ferraguti
- first_name: Philip
full_name: Cobden, Philip M
last_name: Cobden
- first_name: Marie
full_name: Pollard, Marie
last_name: Pollard
- first_name: David
full_name: Cope, David W
last_name: Cope
- first_name: Ryuichi
full_name: Ryuichi Shigemoto
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Masahiko
full_name: Watanabe, Masahiko
last_name: Watanabe
- first_name: Péter
full_name: Somogyi, Péter
last_name: Somogyi
citation:
ama: Ferraguti F, Cobden P, Pollard M, et al. Immunolocalization of metabotropic
glutamate receptor 1α (mGluR1α) in distinct classes of interneuron in the CA1
region of the rat hippocampus. Hippocampus. 2004;14(2):193-215. doi:10.1002/hipo.10163
apa: Ferraguti, F., Cobden, P., Pollard, M., Cope, D., Shigemoto, R., Watanabe,
M., & Somogyi, P. (2004). Immunolocalization of metabotropic glutamate receptor
1α (mGluR1α) in distinct classes of interneuron in the CA1 region of the rat hippocampus.
Hippocampus. Wiley-Blackwell. https://doi.org/10.1002/hipo.10163
chicago: Ferraguti, Francesco, Philip Cobden, Marie Pollard, David Cope, Ryuichi
Shigemoto, Masahiko Watanabe, and Péter Somogyi. “Immunolocalization of Metabotropic
Glutamate Receptor 1α (MGluR1α) in Distinct Classes of Interneuron in the CA1
Region of the Rat Hippocampus.” Hippocampus. Wiley-Blackwell, 2004. https://doi.org/10.1002/hipo.10163.
ieee: F. Ferraguti et al., “Immunolocalization of metabotropic glutamate
receptor 1α (mGluR1α) in distinct classes of interneuron in the CA1 region of
the rat hippocampus,” Hippocampus, vol. 14, no. 2. Wiley-Blackwell, pp.
193–215, 2004.
ista: Ferraguti F, Cobden P, Pollard M, Cope D, Shigemoto R, Watanabe M, Somogyi
P. 2004. Immunolocalization of metabotropic glutamate receptor 1α (mGluR1α) in
distinct classes of interneuron in the CA1 region of the rat hippocampus. Hippocampus.
14(2), 193–215.
mla: Ferraguti, Francesco, et al. “Immunolocalization of Metabotropic Glutamate
Receptor 1α (MGluR1α) in Distinct Classes of Interneuron in the CA1 Region of
the Rat Hippocampus.” Hippocampus, vol. 14, no. 2, Wiley-Blackwell, 2004,
pp. 193–215, doi:10.1002/hipo.10163.
short: F. Ferraguti, P. Cobden, M. Pollard, D. Cope, R. Shigemoto, M. Watanabe,
P. Somogyi, Hippocampus 14 (2004) 193–215.
date_created: 2018-12-11T11:58:50Z
date_published: 2004-01-01T00:00:00Z
date_updated: 2021-01-12T06:58:46Z
day: '01'
doi: 10.1002/hipo.10163
extern: 1
intvolume: ' 14'
issue: '2'
month: '01'
page: 193 - 215
publication: Hippocampus
publication_status: published
publisher: Wiley-Blackwell
publist_id: '4256'
quality_controlled: 0
status: public
title: Immunolocalization of metabotropic glutamate receptor 1α (mGluR1α) in distinct
classes of interneuron in the CA1 region of the rat hippocampus
type: journal_article
volume: 14
year: '2004'
...
---
_id: '2643'
abstract:
- lang: eng
text: Metabotropic γ-aminobutyric acid receptors (GABAB) are involved in pre- and
postsynaptic inhibitory effects upon auditory neurons and have been implicated
in different aspects of acoustic information processing. To understand better
the mechanisms by which GABAB receptors mediate their inhibitory effects, we used
pre-embedding immunocytochemical techniques combined with quantification of immunogold
particles to reveal the precise subcellular distribution of the GABAB1 subunit
in the rat dorsal cochlear nucleus. At the light microscopic level, GABAB1 was
detected in all divisions of the cochlear complex. The most intense immunoreactivity
for GABAB1 was found in the dorsal cochlear nucleus, whereas immunoreactivity
in the anteroventral and posteroventral cochlear nuclei was very low. In the dorsal
cochlear nucleus, a punctate labeling was observed in the superficial (molecular
and fusiform cell) layers. At the electron microscopic level, GABAB1 was found
at both post- and presynaptic locations. Postsynaptically, GABAB1 was localized
mainly in the dendritic spines of presumed fusiform cells. Quantitative immunogold
immunocytochemistry revealed that the highest concentration of GABA B1 in the
plasma membrane was in dendritic spines, followed by dendritic shafts and somata.
Thus, the most intense immunoreactivity for GABAB1 was observed in dendritic spines
with a high density of immunogold particles at extrasynaptic sites, peaking around
300 nm from glutamatergic synapses. This is in contrast to GABAergic synapses,
in which GABAB1 was only occasionally found. Presynaptically, receptor immunoreactivity
was detected primarily in axospinous endings, probably from granule cells, in
both the active zone and extrasynaptic sites. The localization of GABAB1 relative
to synaptic sites in the DCN suggests a role for the receptor in the regulation
of dendritic excitability and excitatory inputs.
author:
- first_name: Rafael
full_name: Luján, Rafael
last_name: Luján
- first_name: Ryuichi
full_name: Ryuichi Shigemoto
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Ákos
full_name: Kulik, Ákos
last_name: Kulik
- first_name: José
full_name: Juíz, José M
last_name: Juíz
citation:
ama: Luján R, Shigemoto R, Kulik Á, Juíz J. Localization of the GABAB receptor 1a/b
subunit relative to glutamatergic synapses in the dorsal cochlear nucleus of the
rat. Journal of Comparative Neurology. 2004;475(1):36-46. doi:10.1002/cne.20160
apa: Luján, R., Shigemoto, R., Kulik, Á., & Juíz, J. (2004). Localization of
the GABAB receptor 1a/b subunit relative to glutamatergic synapses in the dorsal
cochlear nucleus of the rat. Journal of Comparative Neurology. Wiley-Blackwell.
https://doi.org/10.1002/cne.20160
chicago: Luján, Rafael, Ryuichi Shigemoto, Ákos Kulik, and José Juíz. “Localization
of the GABAB Receptor 1a/b Subunit Relative to Glutamatergic Synapses in the Dorsal
Cochlear Nucleus of the Rat.” Journal of Comparative Neurology. Wiley-Blackwell,
2004. https://doi.org/10.1002/cne.20160.
ieee: R. Luján, R. Shigemoto, Á. Kulik, and J. Juíz, “Localization of the GABAB
receptor 1a/b subunit relative to glutamatergic synapses in the dorsal cochlear
nucleus of the rat,” Journal of Comparative Neurology, vol. 475, no. 1.
Wiley-Blackwell, pp. 36–46, 2004.
ista: Luján R, Shigemoto R, Kulik Á, Juíz J. 2004. Localization of the GABAB receptor
1a/b subunit relative to glutamatergic synapses in the dorsal cochlear nucleus
of the rat. Journal of Comparative Neurology. 475(1), 36–46.
mla: Luján, Rafael, et al. “Localization of the GABAB Receptor 1a/b Subunit Relative
to Glutamatergic Synapses in the Dorsal Cochlear Nucleus of the Rat.” Journal
of Comparative Neurology, vol. 475, no. 1, Wiley-Blackwell, 2004, pp. 36–46,
doi:10.1002/cne.20160.
short: R. Luján, R. Shigemoto, Á. Kulik, J. Juíz, Journal of Comparative Neurology
475 (2004) 36–46.
date_created: 2018-12-11T11:58:50Z
date_published: 2004-07-12T00:00:00Z
date_updated: 2021-01-12T06:58:46Z
day: '12'
doi: 10.1002/cne.20160
extern: 1
intvolume: ' 475'
issue: '1'
month: '07'
page: 36 - 46
publication: Journal of Comparative Neurology
publication_status: published
publisher: Wiley-Blackwell
publist_id: '4254'
quality_controlled: 0
status: public
title: Localization of the GABAB receptor 1a/b subunit relative to glutamatergic synapses
in the dorsal cochlear nucleus of the rat
type: journal_article
volume: 475
year: '2004'
...
---
_id: '2644'
abstract:
- lang: eng
text: The release of GABA in synapses is modulated by presynaptic metabotropic glutamate
receptors (mGluRs). We tested whether GABA release to identified hippocampal neurons
is influenced by group III mGluR activation using the agonist L-(+)-2-amino-4-phosphonobutyric
acid (L-AP4) on inhibitory postsynaptic currents (IPSCs) evoked in CA1 interneurons
and pyramidal cells. In interneurons, characterized with biocytin and immunolabelling
for somatostatin, evoked IPSCs were depressed by 50 μM L-AP4 (activating mGluR4
and 8) to 68±6% of control, but they were rarely depressed in pyramidal cells
(96±4% of control). At 300-500 μM concentration (activating mGluR4, 7 and 8),
L-AP4 depressed IPSCs in both interneurons (to 70±6%) and pyramidal cells (to
67±4%). The change in trial-to-trial variability and in paired-pulse depression
indicated a presynaptic action. In interneurons, the degree of IPSC depression
was variable (to 9-87%), and a third of IPSCs were not affected by L-AP4. The
L-AP4-evoked IPSC depression was blocked by LY341495. The depression of IPSCs
was similar in O-LM cells and other interneurons. The lack of cell-type selectivity
and the similar efficacy of different concentrations of L-AP4 suggest that several
group III mGluRs are involved in the depression of IPSCs. Electron microscopic
immunocytochemistry confirmed that mGluR4, mGluR7a and mGluR8a occur in the presynaptic
active zone of GABAergic terminals on interneurons, but not on those innervating
pyramidal cells. The high variability of L-AP4-evoked IPSC suppression is in line
with the selective expression of presynaptic mGluRs by several distinct types
of GABAergic neuron innervating each interneuron type.
author:
- first_name: Naoki
full_name: Kogo, Naoki
last_name: Kogo
- first_name: Yannis
full_name: Dalezios, Yannis
last_name: Dalezios
- first_name: Marco
full_name: Capogna,Marco
last_name: Capogna
- first_name: Francesco
full_name: Ferraguti, Francesco
last_name: Ferraguti
- first_name: Ryuichi
full_name: Ryuichi Shigemoto
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Péter
full_name: Somogyi, Péter
last_name: Somogyi
citation:
ama: Kogo N, Dalezios Y, Capogna M, Ferraguti F, Shigemoto R, Somogyi P. Depression
of GABAergic input to identified hippocampal neurons by group III metabotropic
glutamate receptors in the rat. European Journal of Neuroscience. 2004;19(10):2727-2740.
doi:10.1111/j.0953-816X.2004.03394.x
apa: Kogo, N., Dalezios, Y., Capogna, M., Ferraguti, F., Shigemoto, R., & Somogyi,
P. (2004). Depression of GABAergic input to identified hippocampal neurons by
group III metabotropic glutamate receptors in the rat. European Journal of
Neuroscience. Wiley-Blackwell. https://doi.org/10.1111/j.0953-816X.2004.03394.x
chicago: Kogo, Naoki, Yannis Dalezios, Marco Capogna, Francesco Ferraguti, Ryuichi
Shigemoto, and Péter Somogyi. “Depression of GABAergic Input to Identified Hippocampal
Neurons by Group III Metabotropic Glutamate Receptors in the Rat.” European
Journal of Neuroscience. Wiley-Blackwell, 2004. https://doi.org/10.1111/j.0953-816X.2004.03394.x.
ieee: N. Kogo, Y. Dalezios, M. Capogna, F. Ferraguti, R. Shigemoto, and P. Somogyi,
“Depression of GABAergic input to identified hippocampal neurons by group III
metabotropic glutamate receptors in the rat,” European Journal of Neuroscience,
vol. 19, no. 10. Wiley-Blackwell, pp. 2727–2740, 2004.
ista: Kogo N, Dalezios Y, Capogna M, Ferraguti F, Shigemoto R, Somogyi P. 2004.
Depression of GABAergic input to identified hippocampal neurons by group III metabotropic
glutamate receptors in the rat. European Journal of Neuroscience. 19(10), 2727–2740.
mla: Kogo, Naoki, et al. “Depression of GABAergic Input to Identified Hippocampal
Neurons by Group III Metabotropic Glutamate Receptors in the Rat.” European
Journal of Neuroscience, vol. 19, no. 10, Wiley-Blackwell, 2004, pp. 2727–40,
doi:10.1111/j.0953-816X.2004.03394.x.
short: N. Kogo, Y. Dalezios, M. Capogna, F. Ferraguti, R. Shigemoto, P. Somogyi,
European Journal of Neuroscience 19 (2004) 2727–2740.
date_created: 2018-12-11T11:58:50Z
date_published: 2004-05-01T00:00:00Z
date_updated: 2021-01-12T06:58:46Z
day: '01'
doi: 10.1111/j.0953-816X.2004.03394.x
extern: 1
intvolume: ' 19'
issue: '10'
month: '05'
page: 2727 - 2740
publication: European Journal of Neuroscience
publication_status: published
publisher: Wiley-Blackwell
publist_id: '4255'
quality_controlled: 0
status: public
title: Depression of GABAergic input to identified hippocampal neurons by group III
metabotropic glutamate receptors in the rat
type: journal_article
volume: 19
year: '2004'
...
---
_id: '2645'
abstract:
- lang: eng
text: 'The globus pallidus (GP) is a critical component of the basal ganglia circuitry
controlling motor behavior. Dysregulation of GP activity has been implicated in
a number of psychomotor disorders, including Parkinson''s disease (PD), in which
a cardinal feature of the pathophysiology is an alteration in the pattern and
synchrony of discharge in GP neurons. Yet the determinants of this activity in
GP neurons are poorly understood. To help fill this gap, electrophysiological,
molecular, and computational approaches were used to identify and characterize
GABAergic GP neurons in tissue slices from rodents. In vitro, GABAergic GP neurons
generate a regular, autonomous, single-spike pacemaker activity. Hyperpolarization-activated,
cyclic nucleotide-gated cation (HCN) channels make an important contribution to
this process: their blockade with ZD7288 significantly slowed discharge rate and
decreased its regularity. HCN currents evoked by somatic voltage clamp had fast
and slow components. Single-cell RT-PCR and immunohistochemical approaches revealed
robust expression of HCN2 subunits as well as significant levels of HCN1 subunits
in GABAergic GP neurons. Transient activation of striatal GABAergic input to GP
neurons led to a resetting of rhythmic discharge that was dependent on HCN currents.
Simulations suggested that the ability of transient striatal GABAergic input to
reset pacemaking was dependent on dendritic HCN2/HCN1 channels. Together, these
studies show that HCN channels in GABAergic GP neurons are key determinants of
the regularity and rate of pacemaking as well as striatal resetting of this activity,
implicating HCN channels in the emergence of synchrony in PD.'
author:
- first_name: Savio
full_name: Chan, Savio
last_name: Chan
- first_name: Ryuichi
full_name: Ryuichi Shigemoto
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Jeff
full_name: Mercer, Jeff N
last_name: Mercer
- first_name: James
full_name: Surmeier, James D
last_name: Surmeier
citation:
ama: Chan S, Shigemoto R, Mercer J, Surmeier J. HCN2 and HCN1 channels govern the
regularity of autonomous pacemaking and synaptic resetting in globus pallidus
neurons. Journal of Neuroscience. 2004;24(44):9921-9932. doi:10.1523/JNEUROSCI.2162-04.2004
apa: Chan, S., Shigemoto, R., Mercer, J., & Surmeier, J. (2004). HCN2 and HCN1
channels govern the regularity of autonomous pacemaking and synaptic resetting
in globus pallidus neurons. Journal of Neuroscience. Society for Neuroscience.
https://doi.org/10.1523/JNEUROSCI.2162-04.2004
chicago: Chan, Savio, Ryuichi Shigemoto, Jeff Mercer, and James Surmeier. “HCN2
and HCN1 Channels Govern the Regularity of Autonomous Pacemaking and Synaptic
Resetting in Globus Pallidus Neurons.” Journal of Neuroscience. Society
for Neuroscience, 2004. https://doi.org/10.1523/JNEUROSCI.2162-04.2004.
ieee: S. Chan, R. Shigemoto, J. Mercer, and J. Surmeier, “HCN2 and HCN1 channels
govern the regularity of autonomous pacemaking and synaptic resetting in globus
pallidus neurons,” Journal of Neuroscience, vol. 24, no. 44. Society for
Neuroscience, pp. 9921–9932, 2004.
ista: Chan S, Shigemoto R, Mercer J, Surmeier J. 2004. HCN2 and HCN1 channels govern
the regularity of autonomous pacemaking and synaptic resetting in globus pallidus
neurons. Journal of Neuroscience. 24(44), 9921–9932.
mla: Chan, Savio, et al. “HCN2 and HCN1 Channels Govern the Regularity of Autonomous
Pacemaking and Synaptic Resetting in Globus Pallidus Neurons.” Journal of Neuroscience,
vol. 24, no. 44, Society for Neuroscience, 2004, pp. 9921–32, doi:10.1523/JNEUROSCI.2162-04.2004.
short: S. Chan, R. Shigemoto, J. Mercer, J. Surmeier, Journal of Neuroscience 24
(2004) 9921–9932.
date_created: 2018-12-11T11:58:51Z
date_published: 2004-11-03T00:00:00Z
date_updated: 2021-01-12T06:58:47Z
day: '03'
doi: 10.1523/JNEUROSCI.2162-04.2004
extern: 1
intvolume: ' 24'
issue: '44'
month: '11'
page: 9921 - 9932
publication: Journal of Neuroscience
publication_status: published
publisher: Society for Neuroscience
publist_id: '4252'
quality_controlled: 0
status: public
title: HCN2 and HCN1 channels govern the regularity of autonomous pacemaking and synaptic
resetting in globus pallidus neurons
type: journal_article
volume: 24
year: '2004'
...
---
_id: '2646'
abstract:
- lang: eng
text: Metabotropic γ-aminobutyric acid receptors (GABAB) play modulatory roles in
central synaptic transmission and are involved in controlling neuronal migration
during development. We used immunohistochemical methods to elucidate the expression
pattern as well as the cellular and the precise subcellular localization of the
GABAB1a/b and GABAB2 subunits in the rat hippocampus during prenatal and postnatal
development. At the light microscopic level, both GABABB1a/b and GABAB2 were expressed
in the hippocampal primordium from embryonic day E14. During postnatal development,
immunoreactivity for GABAB1a/b and GABAB2 was distributed mainly in pyramidal
cells, with discrete GABABB1a/b-immunopositive cell bodies of interneurons present
throughout the hippocampus. Using double immunofluorescence, we demonstrated that
during the second week of postnatal development, GABAB1a/b but not GABAB2 was
expressed in glial cells throughout the hippocampal formation. At the electron
microscopic level, GABAB1a/b and GABAB2 showed a similar distribution pattern
during postnatal development. Thus, at all ages the two receptor subunits were
located postsynaptically in dendritic spines and shafts at extrasynaptic and perisynaptic
sites in both pyramidal and nonpyramidal cells. We further demonstrated that the
two subunits were localized presynaptically along the extrasynaptic plasma membrane
of axon terminals and along the presynaptic active zone in both asymmetrical and,
to a lesser extent, symmetrical synapses. These results suggest that GABAB receptors
are widely expressed in the hippocampus throughout development and that GABABB1a/b
and GABAB2 form both pre- and postsynaptic receptors.
author:
- first_name: Guillermina
full_name: López-Bendito, Guillermina
last_name: López Bendito
- first_name: Ryuichi
full_name: Ryuichi Shigemoto
id: 499F3ABC-F248-11E8-B48F-1D18A9856A87
last_name: Shigemoto
orcid: 0000-0001-8761-9444
- first_name: Ákos
full_name: Kulik, Ákos
last_name: Kulik
- first_name: Imre
full_name: Vida, Imre
last_name: Vida
- first_name: Alfonso
full_name: Fairén, Alfonso
last_name: Fairén
- first_name: Rafael
full_name: Luján, Rafael
last_name: Luján
citation:
ama: López Bendito G, Shigemoto R, Kulik Á, Vida I, Fairén A, Luján R. Distribution
of metabotropic GABA receptor subunits GABAB1a/b and GABAB2 in the rat hippocampus
during prenatal and postnatal development. Hippocampus. 2004;14(7):836-848.
doi:10.1002/hipo.10221
apa: López Bendito, G., Shigemoto, R., Kulik, Á., Vida, I., Fairén, A., & Luján,
R. (2004). Distribution of metabotropic GABA receptor subunits GABAB1a/b and
GABAB2 in the rat hippocampus during prenatal and postnatal development. Hippocampus.
Wiley-Blackwell. https://doi.org/10.1002/hipo.10221
chicago: López Bendito, Guillermina, Ryuichi Shigemoto, Ákos Kulik, Imre Vida, Alfonso
Fairén, and Rafael Luján. “ Distribution of Metabotropic GABA Receptor Subunits
GABAB1a/b and GABAB2 in the Rat Hippocampus during Prenatal and Postnatal Development.”
Hippocampus. Wiley-Blackwell, 2004. https://doi.org/10.1002/hipo.10221.
ieee: G. López Bendito, R. Shigemoto, Á. Kulik, I. Vida, A. Fairén, and R. Luján,
“ Distribution of metabotropic GABA receptor subunits GABAB1a/b and GABAB2 in
the rat hippocampus during prenatal and postnatal development,” Hippocampus,
vol. 14, no. 7. Wiley-Blackwell, pp. 836–848, 2004.
ista: López Bendito G, Shigemoto R, Kulik Á, Vida I, Fairén A, Luján R. 2004. Distribution
of metabotropic GABA receptor subunits GABAB1a/b and GABAB2 in the rat hippocampus
during prenatal and postnatal development. Hippocampus. 14(7), 836–848.
mla: López Bendito, Guillermina, et al. “ Distribution of Metabotropic GABA Receptor
Subunits GABAB1a/b and GABAB2 in the Rat Hippocampus during Prenatal and Postnatal
Development.” Hippocampus, vol. 14, no. 7, Wiley-Blackwell, 2004, pp. 836–48,
doi:10.1002/hipo.10221.
short: G. López Bendito, R. Shigemoto, Á. Kulik, I. Vida, A. Fairén, R. Luján, Hippocampus
14 (2004) 836–848.
date_created: 2018-12-11T11:58:51Z
date_published: 2004-01-01T00:00:00Z
date_updated: 2021-01-12T06:58:47Z
day: '01'
doi: 10.1002/hipo.10221
extern: 1
intvolume: ' 14'
issue: '7'
month: '01'
page: 836 - 848
publication: Hippocampus
publication_status: published
publisher: Wiley-Blackwell
publist_id: '4251'
quality_controlled: 0
status: public
title: ' Distribution of metabotropic GABA receptor subunits GABAB1a/b and GABAB2
in the rat hippocampus during prenatal and postnatal development'
type: journal_article
volume: 14
year: '2004'
...
---
_id: '2706'
abstract:
- lang: eng
text: The Pauli operator describes the energy of a nonrelativistic quantum particle
with spin in a magnetic field and an external potential. Bounds on the sum of
the negative eigenvalues are called magnetic Lieb-Thirring (MLT) inequalities.
The purpose of this paper is twofold. First, we prove a new MLT inequality in
a simple way. Second, we give a short summary of our recent proof of a more refined
MLT inequality(8) and we explain the differences between the two results and methods.
The main feature of both estimates, compared to earlier results, is that in the
large field regime they grow with the optimal (first) power of the strength of
the magnetic field. As a byproduct of the method, we also obtain optimal upper
bounds on the pointwise density of zero energy eigenfunctions of the Dirac operator.
author:
- first_name: László
full_name: László Erdös
id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
last_name: Erdös
orcid: 0000-0001-5366-9603
- first_name: Jan
full_name: Solovej, Jan P
last_name: Solovej
citation:
ama: Erdös L, Solovej J. Magnetic Lieb-Thirring inequalities with optimal dependence
on the field strength. Journal of Statistical Physics. 2004;116(1-4):475-506.
doi:10.1023/B:JOSS.0000037216.45270.1d
apa: Erdös, L., & Solovej, J. (2004). Magnetic Lieb-Thirring inequalities with
optimal dependence on the field strength. Journal of Statistical Physics.
Springer. https://doi.org/10.1023/B:JOSS.0000037216.45270.1d
chicago: Erdös, László, and Jan Solovej. “Magnetic Lieb-Thirring Inequalities with
Optimal Dependence on the Field Strength.” Journal of Statistical Physics.
Springer, 2004. https://doi.org/10.1023/B:JOSS.0000037216.45270.1d.
ieee: L. Erdös and J. Solovej, “Magnetic Lieb-Thirring inequalities with optimal
dependence on the field strength,” Journal of Statistical Physics, vol.
116, no. 1–4. Springer, pp. 475–506, 2004.
ista: Erdös L, Solovej J. 2004. Magnetic Lieb-Thirring inequalities with optimal
dependence on the field strength. Journal of Statistical Physics. 116(1–4), 475–506.
mla: Erdös, László, and Jan Solovej. “Magnetic Lieb-Thirring Inequalities with Optimal
Dependence on the Field Strength.” Journal of Statistical Physics, vol.
116, no. 1–4, Springer, 2004, pp. 475–506, doi:10.1023/B:JOSS.0000037216.45270.1d.
short: L. Erdös, J. Solovej, Journal of Statistical Physics 116 (2004) 475–506.
date_created: 2018-12-11T11:59:10Z
date_published: 2004-08-01T00:00:00Z
date_updated: 2021-01-12T06:59:10Z
day: '01'
doi: 10.1023/B:JOSS.0000037216.45270.1d
extern: 1
intvolume: ' 116'
issue: 1-4
month: '08'
page: 475 - 506
publication: Journal of Statistical Physics
publication_status: published
publisher: Springer
publist_id: '4190'
quality_controlled: 0
status: public
title: Magnetic Lieb-Thirring inequalities with optimal dependence on the field strength
type: journal_article
volume: 116
year: '2004'
...
---
_id: '2707'
abstract:
- lang: eng
text: We give a nonrigorous derivation of the nonlinear Boltzmann equation from
the Schrödinger evolution of interacting fermions. The argument is based mainly
on the assumption that a quasifree initial state satisfies a property called restricted
quasifreeness in the weak coupling limit at any later time. By definition, a state
is called restricted quasifree if the four-point and the eight-point functions
of the state factorize in the same manner as in a quasifree state.
author:
- first_name: László
full_name: László Erdös
id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
last_name: Erdös
orcid: 0000-0001-5366-9603
- first_name: Manfred
full_name: Salmhofer, Manfred
last_name: Salmhofer
- first_name: Horng
full_name: Yau, Horng-Tzer
last_name: Yau
citation:
ama: Erdös L, Salmhofer M, Yau H. On the quantum Boltzmann equation. Journal
of Statistical Physics. 2004;116(1-4):367-380. doi:10.1023/B:JOSS.0000037224.56191.ed
apa: Erdös, L., Salmhofer, M., & Yau, H. (2004). On the quantum Boltzmann equation.
Journal of Statistical Physics. Springer. https://doi.org/10.1023/B:JOSS.0000037224.56191.ed
chicago: Erdös, László, Manfred Salmhofer, and Horng Yau. “On the Quantum Boltzmann
Equation.” Journal of Statistical Physics. Springer, 2004. https://doi.org/10.1023/B:JOSS.0000037224.56191.ed.
ieee: L. Erdös, M. Salmhofer, and H. Yau, “On the quantum Boltzmann equation,” Journal
of Statistical Physics, vol. 116, no. 1–4. Springer, pp. 367–380, 2004.
ista: Erdös L, Salmhofer M, Yau H. 2004. On the quantum Boltzmann equation. Journal
of Statistical Physics. 116(1–4), 367–380.
mla: Erdös, László, et al. “On the Quantum Boltzmann Equation.” Journal of Statistical
Physics, vol. 116, no. 1–4, Springer, 2004, pp. 367–80, doi:10.1023/B:JOSS.0000037224.56191.ed.
short: L. Erdös, M. Salmhofer, H. Yau, Journal of Statistical Physics 116 (2004)
367–380.
date_created: 2018-12-11T11:59:11Z
date_published: 2004-08-01T00:00:00Z
date_updated: 2021-01-12T06:59:11Z
day: '01'
doi: 10.1023/B:JOSS.0000037224.56191.ed
extern: 1
intvolume: ' 116'
issue: 1-4
month: '08'
page: 367 - 380
publication: Journal of Statistical Physics
publication_status: published
publisher: Springer
publist_id: '4189'
quality_controlled: 0
status: public
title: On the quantum Boltzmann equation
type: journal_article
volume: 116
year: '2004'
...
---
_id: '2741'
abstract:
- lang: eng
text: 'The Pauli operator describes the energy of a nonrelativistic quantum particle
with spin 1/2 in a magnetic field and an external potential. A new Lieb-Thirring
type inequality on the sum of the negative eigenvalues is presented. The main
feature compared to earlier results is that in the large field regime the present
estimate grows with the optimal (first) power of the strength of the magnetic
field. As a byproduct of the method, we also obtain an optimal upper bound on
the pointwise density of zero energy eigenfunctions of the Dirac operator. The
main technical tools are: (i) a new localization scheme for the square of the
resolvent of a general class of second order elliptic operators; (ii) a geometric
construction of a Dirac operator with a constant magnetic field that approximates
the original Dirac operator in a tubular neighborhood of a fixed field line. The
errors may depend on the regularity of the magnetic field but they are uniform
in the field strength.'
author:
- first_name: László
full_name: László Erdös
id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
last_name: Erdös
orcid: 0000-0001-5366-9603
- first_name: Jan
full_name: Solovej, Jan P
last_name: Solovej
citation:
ama: Erdös L, Solovej J. Uniform Lieb-Thirring inequality for the three-dimensional
Pauli operator with a strong non-homogeneous magnetic field. Annales Henri
Poincare. 2004;5(4):671-741. doi:10.1007/s00023-004-0180-x
apa: Erdös, L., & Solovej, J. (2004). Uniform Lieb-Thirring inequality for the
three-dimensional Pauli operator with a strong non-homogeneous magnetic field.
Annales Henri Poincare. Birkhäuser. https://doi.org/10.1007/s00023-004-0180-x
chicago: Erdös, László, and Jan Solovej. “Uniform Lieb-Thirring Inequality for the
Three-Dimensional Pauli Operator with a Strong Non-Homogeneous Magnetic Field.”
Annales Henri Poincare. Birkhäuser, 2004. https://doi.org/10.1007/s00023-004-0180-x.
ieee: L. Erdös and J. Solovej, “Uniform Lieb-Thirring inequality for the three-dimensional
Pauli operator with a strong non-homogeneous magnetic field,” Annales Henri
Poincare, vol. 5, no. 4. Birkhäuser, pp. 671–741, 2004.
ista: Erdös L, Solovej J. 2004. Uniform Lieb-Thirring inequality for the three-dimensional
Pauli operator with a strong non-homogeneous magnetic field. Annales Henri Poincare.
5(4), 671–741.
mla: Erdös, László, and Jan Solovej. “Uniform Lieb-Thirring Inequality for the Three-Dimensional
Pauli Operator with a Strong Non-Homogeneous Magnetic Field.” Annales Henri
Poincare, vol. 5, no. 4, Birkhäuser, 2004, pp. 671–741, doi:10.1007/s00023-004-0180-x.
short: L. Erdös, J. Solovej, Annales Henri Poincare 5 (2004) 671–741.
date_created: 2018-12-11T11:59:21Z
date_published: 2004-08-01T00:00:00Z
date_updated: 2021-01-12T06:59:24Z
day: '01'
doi: 10.1007/s00023-004-0180-x
extern: 1
intvolume: ' 5'
issue: '4'
month: '08'
page: 671 - 741
publication: Annales Henri Poincare
publication_status: published
publisher: Birkhäuser
publist_id: '4151'
quality_controlled: 0
status: public
title: Uniform Lieb-Thirring inequality for the three-dimensional Pauli operator with
a strong non-homogeneous magnetic field
type: journal_article
volume: 5
year: '2004'
...
---
_id: '2742'
abstract:
- lang: eng
text: We consider a system of N weakly interacting fermions with a real analytic
pair interaction. We prove that for a general class of initial data there exists
a fixed time T such that the difference between the one particle density matrix
of this system and the solution of the nonlinear Hartree equation is of order
N−1 for any time t⩽T.
author:
- first_name: Alexander
full_name: Elgart, Alexander
last_name: Elgart
- first_name: László
full_name: László Erdös
id: 4DBD5372-F248-11E8-B48F-1D18A9856A87
last_name: Erdös
orcid: 0000-0001-5366-9603
- first_name: Benjamin
full_name: Schlein, Benjamin
last_name: Schlein
- first_name: Horng
full_name: Yau, Horng-Tzer
last_name: Yau
citation:
ama: Elgart A, Erdös L, Schlein B, Yau H. Nonlinear Hartree equation as the mean
field limit of weakly coupled fermions. Journal de Mathématiques Pures et Appliquées.
2004;83(10):1241-1273. doi:10.1016/j.matpur.2004.03.006
apa: Elgart, A., Erdös, L., Schlein, B., & Yau, H. (2004). Nonlinear Hartree
equation as the mean field limit of weakly coupled fermions. Journal de Mathématiques
Pures et Appliquées. Elsevier. https://doi.org/10.1016/j.matpur.2004.03.006
chicago: Elgart, Alexander, László Erdös, Benjamin Schlein, and Horng Yau. “Nonlinear
Hartree Equation as the Mean Field Limit of Weakly Coupled Fermions.” Journal
de Mathématiques Pures et Appliquées. Elsevier, 2004. https://doi.org/10.1016/j.matpur.2004.03.006.
ieee: A. Elgart, L. Erdös, B. Schlein, and H. Yau, “Nonlinear Hartree equation as
the mean field limit of weakly coupled fermions,” Journal de Mathématiques
Pures et Appliquées, vol. 83, no. 10. Elsevier, pp. 1241–1273, 2004.
ista: Elgart A, Erdös L, Schlein B, Yau H. 2004. Nonlinear Hartree equation as the
mean field limit of weakly coupled fermions. Journal de Mathématiques Pures et
Appliquées. 83(10), 1241–1273.
mla: Elgart, Alexander, et al. “Nonlinear Hartree Equation as the Mean Field Limit
of Weakly Coupled Fermions.” Journal de Mathématiques Pures et Appliquées,
vol. 83, no. 10, Elsevier, 2004, pp. 1241–73, doi:10.1016/j.matpur.2004.03.006.
short: A. Elgart, L. Erdös, B. Schlein, H. Yau, Journal de Mathématiques Pures et
Appliquées 83 (2004) 1241–1273.
date_created: 2018-12-11T11:59:22Z
date_published: 2004-10-01T00:00:00Z
date_updated: 2021-01-12T06:59:24Z
day: '01'
doi: 10.1016/j.matpur.2004.03.006
extern: 1
intvolume: ' 83'
issue: '10'
month: '10'
page: 1241 - 1273
publication: Journal de Mathématiques Pures et Appliquées
publication_status: published
publisher: Elsevier
publist_id: '4150'
quality_controlled: 0
status: public
title: Nonlinear Hartree equation as the mean field limit of weakly coupled fermions
type: journal_article
volume: 83
year: '2004'
...
---
_id: '2786'
abstract:
- lang: eng
text: Transition to turbulence in pipe flow is one of the most fundamental and longest-
standing problems in fluid dynamics. Stability theory suggests that the flow remains
laminar for all flow rates, but in practice pipe flow becomes turbulent even at
moderate speeds. This transition drastically affects the transport efficiency
of mass, momentum, and heat. On the basis of the recent discovery of unstable
traveling waves in computational studies of the Navier-Stokes equations and ideas
from dynamical systems theory, a model for the transition process has been suggested.
We report experimental observation of these traveling waves in pipe flow, confirming
the proposed transition scenario and suggesting that the dynamics associated with
these unstable states may indeed capture the nature of fluid turbulence.
author:
- first_name: Björn
full_name: Björn Hof
id: 3A374330-F248-11E8-B48F-1D18A9856A87
last_name: Hof
orcid: 0000-0003-2057-2754
- first_name: Casimir
full_name: van Doorne, Casimir W
last_name: Van Doorne
- first_name: Jerry
full_name: Westerweel, Jerry
last_name: Westerweel
- first_name: Frans
full_name: Nieuwstadt, Frans T
last_name: Nieuwstadt
- first_name: Holger
full_name: Faisst, Holger
last_name: Faisst
- first_name: Bruno
full_name: Eckhardt, Bruno
last_name: Eckhardt
- first_name: Håkan
full_name: Wedin, Håkan
last_name: Wedin
- first_name: Richard
full_name: Kersweli, Richard R
last_name: Kersweli
- first_name: Fabian
full_name: Waleffe, Fabian
last_name: Waleffe
citation:
ama: Hof B, Van Doorne C, Westerweel J, et al. Experimental observation of nonlinear
traveling waves in turbulent pipe flow. Science. 2004;305(5690):1594-1598.
doi:10.1126/science.1100393
apa: Hof, B., Van Doorne, C., Westerweel, J., Nieuwstadt, F., Faisst, H., Eckhardt,
B., … Waleffe, F. (2004). Experimental observation of nonlinear traveling waves
in turbulent pipe flow. Science. American Association for the Advancement
of Science. https://doi.org/10.1126/science.1100393
chicago: Hof, Björn, Casimir Van Doorne, Jerry Westerweel, Frans Nieuwstadt, Holger
Faisst, Bruno Eckhardt, Håkan Wedin, Richard Kersweli, and Fabian Waleffe. “Experimental
Observation of Nonlinear Traveling Waves in Turbulent Pipe Flow.” Science.
American Association for the Advancement of Science, 2004. https://doi.org/10.1126/science.1100393.
ieee: B. Hof et al., “Experimental observation of nonlinear traveling waves
in turbulent pipe flow,” Science, vol. 305, no. 5690. American Association
for the Advancement of Science, pp. 1594–1598, 2004.
ista: Hof B, Van Doorne C, Westerweel J, Nieuwstadt F, Faisst H, Eckhardt B, Wedin
H, Kersweli R, Waleffe F. 2004. Experimental observation of nonlinear traveling
waves in turbulent pipe flow. Science. 305(5690), 1594–1598.
mla: Hof, Björn, et al. “Experimental Observation of Nonlinear Traveling Waves in
Turbulent Pipe Flow.” Science, vol. 305, no. 5690, American Association
for the Advancement of Science, 2004, pp. 1594–98, doi:10.1126/science.1100393.
short: B. Hof, C. Van Doorne, J. Westerweel, F. Nieuwstadt, H. Faisst, B. Eckhardt,
H. Wedin, R. Kersweli, F. Waleffe, Science 305 (2004) 1594–1598.
date_created: 2018-12-11T11:59:35Z
date_published: 2004-09-10T00:00:00Z
date_updated: 2021-01-12T06:59:42Z
day: '10'
doi: 10.1126/science.1100393
extern: 1
intvolume: ' 305'
issue: '5690'
month: '09'
page: 1594 - 1598
publication: Science
publication_status: published
publisher: American Association for the Advancement of Science
publist_id: '4103'
quality_controlled: 0
status: public
title: Experimental observation of nonlinear traveling waves in turbulent pipe flow
type: journal_article
volume: 305
year: '2004'
...
---
_id: '2787'
abstract:
- lang: eng
text: The results of experimental and numerical investigations of the onset of oscillatory
convection in a sidewall heated rectangular cavity of molten gallium are reported.
Detailed comparisons are made between experimental observations and calculations
from numerical simulations of a three-dimensional Boussinesq model. The onset
of time-dependence takes place through supercritical Hopf bifurcations and the
loci of critical points in the (Gr, Pr)-plane are qualitatively similar with excellent
agreement between the frequencies of the oscillatory motion. This provides a severe
test of the control of the experiment since the mode of oscillation is extremely
sensitive to imperfections. Detailed numerical investigations reveal that there
are a pair of Hopf bifurcations which exist on two asymmetric states which themselves
arise at a subcritical pitchfork from the symmetric state. There is no evidence
for this in the experiment and this qualitative difference is attributed to non-Boussinesq
perturbations which increase with Gr. However, the antisymmetric spatial structure
of the oscillatory state is robust and is present in both the experiment and the
numerical model. Moreover, the detailed analysis of the numerical results reveals
the origins of the oscillatory instability.
author:
- first_name: Björn
full_name: Björn Hof
id: 3A374330-F248-11E8-B48F-1D18A9856A87
last_name: Hof
orcid: 0000-0003-2057-2754
- first_name: Anne
full_name: Juel, Anne
last_name: Juel
- first_name: Li
full_name: Zhao, Li
last_name: Zhao
- first_name: Daniel
full_name: 'Henry, Daniel '
last_name: Henry
- first_name: Hamda
full_name: Ben Hadid, Hamda
last_name: Ben Hadid
- first_name: Tom
full_name: Mullin, Tom P
last_name: Mullin
citation:
ama: Hof B, Juel A, Zhao L, Henry D, Ben Hadid H, Mullin T. On the onset of oscillatory
convection in molten gallium. Journal of Fluid Mechanics. 2004;515:391-413.
doi:10.1017/S0022112004000527
apa: Hof, B., Juel, A., Zhao, L., Henry, D., Ben Hadid, H., & Mullin, T. (2004).
On the onset of oscillatory convection in molten gallium. Journal of Fluid
Mechanics. Cambridge University Press. https://doi.org/10.1017/S0022112004000527
chicago: Hof, Björn, Anne Juel, Li Zhao, Daniel Henry, Hamda Ben Hadid, and Tom
Mullin. “On the Onset of Oscillatory Convection in Molten Gallium.” Journal
of Fluid Mechanics. Cambridge University Press, 2004. https://doi.org/10.1017/S0022112004000527.
ieee: B. Hof, A. Juel, L. Zhao, D. Henry, H. Ben Hadid, and T. Mullin, “On the onset
of oscillatory convection in molten gallium,” Journal of Fluid Mechanics,
vol. 515. Cambridge University Press, pp. 391–413, 2004.
ista: Hof B, Juel A, Zhao L, Henry D, Ben Hadid H, Mullin T. 2004. On the onset
of oscillatory convection in molten gallium. Journal of Fluid Mechanics. 515,
391–413.
mla: Hof, Björn, et al. “On the Onset of Oscillatory Convection in Molten Gallium.”
Journal of Fluid Mechanics, vol. 515, Cambridge University Press, 2004,
pp. 391–413, doi:10.1017/S0022112004000527.
short: B. Hof, A. Juel, L. Zhao, D. Henry, H. Ben Hadid, T. Mullin, Journal of Fluid
Mechanics 515 (2004) 391–413.
date_created: 2018-12-11T11:59:36Z
date_published: 2004-09-25T00:00:00Z
date_updated: 2021-01-12T06:59:43Z
day: '25'
doi: 10.1017/S0022112004000527
extern: 1
intvolume: ' 515'
month: '09'
page: 391 - 413
publication: Journal of Fluid Mechanics
publication_status: published
publisher: Cambridge University Press
publist_id: '4102'
quality_controlled: 0
status: public
title: On the onset of oscillatory convection in molten gallium
type: journal_article
volume: 515
year: '2004'
...
---
_id: '2997'
abstract:
- lang: eng
text: Polar transport-dependent local accumulation of auxin provides positional
cues for multiple plant patterning processes. This directional auxin flow depends
on the polar subcellular localization of the PIN auxin efflux regulators. Overexpression
of the PINOID protein kinase induces a basal-to-apical shift in PIN localization,
resulting in the loss of auxin gradients and strong defects in embryo and seedling
roots. Conversely, pid loss of function induces an apical-to-basal shift in PIN1
polar targeting at the inflorescence apex, accompanied by defective organogenesis.
Our results show that a PINOID-dependent binary switch controls PIN polarity and
mediates changes in auxin flow to create local gradients for patterning processes.
author:
- first_name: Jirí
full_name: Jirí Friml
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Xiong
full_name: Yang, Xiong
last_name: Yang
- first_name: Marta
full_name: Michniewicz, Marta
last_name: Michniewicz
- first_name: Dolf
full_name: Weijers, Dolf
last_name: Weijers
- first_name: Ab
full_name: Quint, Ab
last_name: Quint
- first_name: Olaf
full_name: Tietz, Olaf
last_name: Tietz
- first_name: René
full_name: Benjamins, René
last_name: Benjamins
- first_name: Pieter
full_name: Ouwerkerk, Pieter B
last_name: Ouwerkerk
- first_name: Karin
full_name: Ljung, Karin
last_name: Ljung
- first_name: Göran
full_name: Sandberg, Göran
last_name: Sandberg
- first_name: Paul
full_name: Hooykaas, Paul J
last_name: Hooykaas
- first_name: Klaus
full_name: Palme, Klaus
last_name: Palme
- first_name: Remko
full_name: Offringa, Remko
last_name: Offringa
citation:
ama: Friml J, Yang X, Michniewicz M, et al. A PINOID-dependent binary switch in
apical-basal PIN polar targeting directs auxin efflux. Science. 2004;306(5697):862-865.
doi:10.1126/science.1100618
apa: Friml, J., Yang, X., Michniewicz, M., Weijers, D., Quint, A., Tietz, O., …
Offringa, R. (2004). A PINOID-dependent binary switch in apical-basal PIN polar
targeting directs auxin efflux. Science. American Association for the Advancement
of Science. https://doi.org/10.1126/science.1100618
chicago: Friml, Jiří, Xiong Yang, Marta Michniewicz, Dolf Weijers, Ab Quint, Olaf
Tietz, René Benjamins, et al. “A PINOID-Dependent Binary Switch in Apical-Basal
PIN Polar Targeting Directs Auxin Efflux.” Science. American Association
for the Advancement of Science, 2004. https://doi.org/10.1126/science.1100618.
ieee: J. Friml et al., “A PINOID-dependent binary switch in apical-basal
PIN polar targeting directs auxin efflux,” Science, vol. 306, no. 5697.
American Association for the Advancement of Science, pp. 862–865, 2004.
ista: Friml J, Yang X, Michniewicz M, Weijers D, Quint A, Tietz O, Benjamins R,
Ouwerkerk P, Ljung K, Sandberg G, Hooykaas P, Palme K, Offringa R. 2004. A PINOID-dependent
binary switch in apical-basal PIN polar targeting directs auxin efflux. Science.
306(5697), 862–865.
mla: Friml, Jiří, et al. “A PINOID-Dependent Binary Switch in Apical-Basal PIN Polar
Targeting Directs Auxin Efflux.” Science, vol. 306, no. 5697, American
Association for the Advancement of Science, 2004, pp. 862–65, doi:10.1126/science.1100618.
short: J. Friml, X. Yang, M. Michniewicz, D. Weijers, A. Quint, O. Tietz, R. Benjamins,
P. Ouwerkerk, K. Ljung, G. Sandberg, P. Hooykaas, K. Palme, R. Offringa, Science
306 (2004) 862–865.
date_created: 2018-12-11T12:00:46Z
date_published: 2004-10-29T00:00:00Z
date_updated: 2021-01-12T07:40:20Z
day: '29'
doi: 10.1126/science.1100618
extern: 1
intvolume: ' 306'
issue: '5697'
month: '10'
page: 862 - 865
publication: Science
publication_status: published
publisher: American Association for the Advancement of Science
publist_id: '3705'
quality_controlled: 0
status: public
title: A PINOID-dependent binary switch in apical-basal PIN polar targeting directs
auxin efflux
type: journal_article
volume: 306
year: '2004'
...
---
_id: '2998'
abstract:
- lang: eng
text: The packaging of the genomic DNA into chromatin in the cell nucleus requires
machineries that facilitate DNA-dependent processes such as transcription in the
presence of repressive chromatin structures. Using co-immunoprecipitation we have
identified in Arabidopsis thaliana cells the FAcilitates Chromatin Transcription
(FACT) complex, consisting of the 120-kDa Spt16 and the 71-kDa SSRP1 proteins.
Indirect immunofluorecence analyses revealed that both FACT subunits co-localize
to nuclei of the majority of cell types in embryos, shoots and roots, whereas
FACT is not present in terminally differentiated cells such as mature trichoblasts
or cells of the root cap. In the nucleus, Spt16 and SSRP1 are found in the cytologically
defined euchromatin of interphase cells independent of the status of DNA replication,
but the proteins are not associated with heterochromatic chromocentres and condensed
mitotic chromosomes. FACT can be detected by chromatin immunoprecipitation over
the entire transcribed region (5′-UTR, coding sequence, 3′-UTR) of actively transcribed
genes, whereas it does not occur at transcriptionally inactive heterochromatic
regions and intergenic regions. FACT localizes to inducible genes only after induction
of transcription, and the association of the complex with the genes correlates
with the level of transcription. Collectively, these results indicate that FACT
assists transcription elongation through plant chromatin.
author:
- first_name: Meg
full_name: Duroux, Meg
last_name: Duroux
- first_name: Andreas
full_name: Houben, Andreas
last_name: Houben
- first_name: Kamil
full_name: Růžička, Kamil
last_name: Růžička
- first_name: Jirí
full_name: Jirí Friml
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
- first_name: Klaus
full_name: Grasser, Klaus D
last_name: Grasser
citation:
ama: Duroux M, Houben A, Růžička K, Friml J, Grasser K. The chromatin remodelling
complex FACT associates with actively transcribed regions of the Arabidopsis genome.
Plant Journal. 2004;40(5):660-671. doi:10.1111/j.1365-313X.2004.02242.x
apa: Duroux, M., Houben, A., Růžička, K., Friml, J., & Grasser, K. (2004). The
chromatin remodelling complex FACT associates with actively transcribed regions
of the Arabidopsis genome. Plant Journal. Wiley-Blackwell. https://doi.org/10.1111/j.1365-313X.2004.02242.x
chicago: Duroux, Meg, Andreas Houben, Kamil Růžička, Jiří Friml, and Klaus Grasser.
“The Chromatin Remodelling Complex FACT Associates with Actively Transcribed Regions
of the Arabidopsis Genome.” Plant Journal. Wiley-Blackwell, 2004. https://doi.org/10.1111/j.1365-313X.2004.02242.x.
ieee: M. Duroux, A. Houben, K. Růžička, J. Friml, and K. Grasser, “The chromatin
remodelling complex FACT associates with actively transcribed regions of the Arabidopsis
genome,” Plant Journal, vol. 40, no. 5. Wiley-Blackwell, pp. 660–671, 2004.
ista: Duroux M, Houben A, Růžička K, Friml J, Grasser K. 2004. The chromatin remodelling
complex FACT associates with actively transcribed regions of the Arabidopsis genome.
Plant Journal. 40(5), 660–671.
mla: Duroux, Meg, et al. “The Chromatin Remodelling Complex FACT Associates with
Actively Transcribed Regions of the Arabidopsis Genome.” Plant Journal,
vol. 40, no. 5, Wiley-Blackwell, 2004, pp. 660–71, doi:10.1111/j.1365-313X.2004.02242.x.
short: M. Duroux, A. Houben, K. Růžička, J. Friml, K. Grasser, Plant Journal 40
(2004) 660–671.
date_created: 2018-12-11T12:00:47Z
date_published: 2004-12-01T00:00:00Z
date_updated: 2021-01-12T07:40:20Z
day: '01'
doi: 10.1111/j.1365-313X.2004.02242.x
extern: 1
intvolume: ' 40'
issue: '5'
month: '12'
page: 660 - 671
publication: Plant Journal
publication_status: published
publisher: Wiley-Blackwell
publist_id: '3703'
quality_controlled: 0
status: public
title: The chromatin remodelling complex FACT associates with actively transcribed
regions of the Arabidopsis genome
type: journal_article
volume: 40
year: '2004'
...
---
_id: '2999'
abstract:
- lang: eng
text: Embryogenesis of flowering plants establishes a basic body plan with apical-basal,
radial and bilateral patterns from the single-celled zygote. Arabidopsis embryogenesis
exhibits a nearly invariant cell division pattern and therefore is an ideal system
for studies of early plant development. However, plant embryos are difficult to
access for experimental manipulation, as they develop deeply inside maternal tissues.
Here we present a method for the culture of zygotic Arabidopsis embryos in vitro.
The technique omits excision of the embryo by culturing the entire ovule, thus
greatly facilitating the time and effort involved. It enables external manipulation
of embryo development and culture from the earliest developmental stages up to
maturity. Administration of various chemical treatments as well as the use of
different molecular markers is demonstrated together with standard techniques
for visualizing gene expression and protein localization in in vitro cultivated
embryos. The presented set of techniques allows for so far unavailable molecular
physiology approaches in the study of early plant development.
author:
- first_name: Michael
full_name: Sauer, Michael
last_name: Sauer
- first_name: Jirí
full_name: Jirí Friml
id: 4159519E-F248-11E8-B48F-1D18A9856A87
last_name: Friml
orcid: 0000-0002-8302-7596
citation:
ama: Sauer M, Friml J. In vitro culture of Arabidopsis embryos within their ovules.
Plant Journal. 2004;40(5):835-843. doi:10.1111/j.1365-313X.2004.02248.x
apa: Sauer, M., & Friml, J. (2004). In vitro culture of Arabidopsis embryos
within their ovules. Plant Journal. Wiley-Blackwell. https://doi.org/10.1111/j.1365-313X.2004.02248.x
chicago: Sauer, Michael, and Jiří Friml. “In Vitro Culture of Arabidopsis Embryos
within Their Ovules.” Plant Journal. Wiley-Blackwell, 2004. https://doi.org/10.1111/j.1365-313X.2004.02248.x.
ieee: M. Sauer and J. Friml, “In vitro culture of Arabidopsis embryos within their
ovules,” Plant Journal, vol. 40, no. 5. Wiley-Blackwell, pp. 835–843, 2004.
ista: Sauer M, Friml J. 2004. In vitro culture of Arabidopsis embryos within their
ovules. Plant Journal. 40(5), 835–843.
mla: Sauer, Michael, and Jiří Friml. “In Vitro Culture of Arabidopsis Embryos within
Their Ovules.” Plant Journal, vol. 40, no. 5, Wiley-Blackwell, 2004, pp.
835–43, doi:10.1111/j.1365-313X.2004.02248.x.
short: M. Sauer, J. Friml, Plant Journal 40 (2004) 835–843.
date_created: 2018-12-11T12:00:47Z
date_published: 2004-12-01T00:00:00Z
date_updated: 2021-01-12T07:40:20Z
day: '01'
doi: 10.1111/j.1365-313X.2004.02248.x
extern: 1
intvolume: ' 40'
issue: '5'
month: '12'
page: 835 - 843
publication: Plant Journal
publication_status: published
publisher: Wiley-Blackwell
publist_id: '3704'
quality_controlled: 0
status: public
title: In vitro culture of Arabidopsis embryos within their ovules
type: journal_article
volume: 40
year: '2004'
...